GenomeNet

Database: Pfam
Entry: DUF4651
LinkDB: DUF4651
Original site: DUF4651 
#=GF ID   DUF4651
#=GF AC   PF15513.9
#=GF DE   Domain of unknown function (DUF4651)
#=GF AU   Godzik A;0000-0002-2425-852X
#=GF SE   JCSG target SP18156A 
#=GF GA   22.00 22.00;
#=GF TC   22.00 40.90;
#=GF NC   21.90 19.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR028105;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   family of short, secreted proteins specific to the Streptococcus
#=GF CC   genus, with distant homologs, not recognized by this HMM, found
#=GF CC   in other cocci. In all sequenced genomes, proteins from  this
#=GF CC   family appear in a conserved genomic context with an
#=GF CC   thioredoxin, tRNA synthase and tRNA binding protein, but the
#=GF CC   functional implication of this is unclear
#=GF SQ   36
#=GS F5X499_STRPX/61-121      AC F5X499.1
#=GS A0A2X3W1A6_9STRE/32-92   AC A0A2X3W1A6.1
#=GS A0A1G6BS27_9STRE/32-92   AC A0A1G6BS27.1
#=GS A0A5C5TAR4_9STRE/24-91   AC A0A5C5TAR4.1
#=GS A4VSM0_STRSY/59-119      AC A4VSM0.1
#=GS F9PZH9_9STRE/34-94       AC F9PZH9.1
#=GS G5KES4_9STRE/34-94       AC G5KES4.1
#=GS A0A3P1V865_9STRE/32-92   AC A0A3P1V865.1
#=GS A0A0F2CTV2_STRCR/34-94   AC A0A0F2CTV2.1
#=GS A0A0E3WEN5_9STRE/20-80   AC A0A0E3WEN5.1
#=GS B9DT12_STRU0/35-95       AC B9DT12.1
#=GS Q5M2H3_STRT2/35-95       AC Q5M2H3.1
#=GS A0A172QAA2_9STRE/54-114  AC A0A172QAA2.1
#=GS A0A2L0D7D7_9STRE/32-91   AC A0A2L0D7D7.1
#=GS G5K4M3_9STRE/32-92       AC G5K4M3.1
#=GS A0A1Q8E6H3_9STRE/32-92   AC A0A1Q8E6H3.1
#=GS A0A139NQ81_9STRE/33-93   AC A0A139NQ81.1
#=GS Q9A1S6_STRP1/32-92       AC Q9A1S6.1
#=GS A0A139NED4_9STRE/34-94   AC A0A139NED4.1
#=GS A0A239SX18_9STRE/10-78   AC A0A239SX18.1
#=GS Q8E223_STRA5/32-92       AC Q8E223.1
#=GS A0A139NHZ1_9STRE/24-82   AC A0A139NHZ1.1
#=GS A8AZF5_STRGC/34-94       AC A8AZF5.1
#=GS F9HJH9_9STRE/34-94       AC F9HJH9.1
#=GS A0A380KXS6_9STRE/34-94   AC A0A380KXS6.1
#=GS Q8CYB9_STRR6/37-97       AC Q8CYB9.1
#=GS A0A4Y9FJ31_9STRE/37-97   AC A0A4Y9FJ31.1
#=GS T1ZHM4_STRIT/34-94       AC T1ZHM4.1
#=GS A0A4R0QQZ4_9STRE/32-92   AC A0A4R0QQZ4.1
#=GS A0A3L9DRX1_9STRE/32-93   AC A0A3L9DRX1.1
#=GS E1M8M9_9STRE/22-82       AC E1M8M9.1
#=GS A0A3L8GS41_STRIN/32-92   AC A0A3L8GS41.1
#=GS A5MA37_STREE/29-89       AC A5MA37.1
#=GS Q8DS63_STRMU/34-94       AC Q8DS63.1
#=GS A3CKG6_STRSV/34-94       AC A3CKG6.1
#=GS G5JND5_STRCG/53-113      AC G5JND5.1
F5X499_STRPX/61-121                 ...........KRQEKIKQAIRDYFSRFDNISVLYVNAFESDKERTTGGLVLEDGRTFQFVYQNGEISYEEE...
A0A2X3W1A6_9STRE/32-92              ...........RQKAAILESVRSVFETLGSLQVLYINDFESSDVFMTGGVVLEDGRVFHFTYDRGQLDYQQE...
A0A1G6BS27_9STRE/32-92              ...........KRRQQILTEVRAFFDSFGTIEVLYINGFESTNTCVKGGVVFDDDVTFLFEYRDGEIDYREE...
A0A5C5TAR4_9STRE/24-91              .qkqttqqvee---KEMTDYLRQFFSQFGQIEVLYFNDYQLDDEARTGGVVMATGQSYEFSYYQGDFTYQE-v..
A4VSM0_STRSY/59-119                 ...........RKKAQALQEVRDFFADLGEIATVYVDETASTQTTLIGGVVMEAGQVFLFENTKGSIQYREE...
F9PZH9_9STRE/34-94                  ...........KTQEELTALVRDYFSEMGEIATFYVQVYESSLERLVGGVIFEDGRHYTFVYEDEDLIYEEE...
G5KES4_9STRE/34-94                  ...........KKRNKVTAQIRSFFEELGTIEVLFLNSYSSNKEMITGGVIMSNGKEYEFTFKNKAIAYRE-v..
A0A3P1V865_9STRE/32-92              ...........RQKAAALKQVRAYFAEFGSIATVFVDEHQSDKNCLIGGVVMEAGPVYLFVNQAGQISYEEE...
A0A0F2CTV2_STRCR/34-94              ...........RNREEIVQIVREFFASRGPIATVYVELYESSDSRTVGGVVLEDDRHFTFVYENGQLTYEEE...
A0A0E3WEN5_9STRE/20-80              ...........RQKAVALRQVREFFADFGTIVTVFVDESQSSKEVLVGGVVMKEGPVYLFENQAGEIIYGEE...
B9DT12_STRU0/35-95                  ...........YQQEKMTADIRQFFSQKGDIELVYFDVPQPQSKERNGGLVMSDGRQYSFTYQKGAIIYQEE...
Q5M2H3_STRT2/35-95                  ...........MKKAALIQDIRQELSHLGPIAVLYTNPTDKENPGLTGGIVLEDGRVYSFVYAEDKLTYEEE...
A0A172QAA2_9STRE/54-114             ..........k-KYELAQAELRQFFGRFGEIAVLYVNELTSDKETVRGGVVMTDGTIYHFRYKDGGIRFREE...
A0A2L0D7D7_9STRE/32-91              ..........a-QKERRMADIRAYFSQFGDIQVVYINDFEDE-HGSSGGVVLTDGRQFDFTYDKGDIIVQE-v..
G5K4M3_9STRE/32-92                  ...........RKQEEIIKQIRQTLATLGEVQVLYVDAKASNHKKVCGGAVLKDGKSYGYCYEKGTVKVEED...
A0A1Q8E6H3_9STRE/32-92              ...........RKKAKALQQVRAFFAEYGEIATVFINEMESSKDRLVGGVVMEDERVYLFENEAGVIWYEEE...
A0A139NQ81_9STRE/33-93              ...........KKKERKILAIRAELLRKGEIAGFYILEEESSGDDLIGGAVLEDGRVFSYEMLGQALTIEEE...
Q9A1S6_STRP1/32-92                  ...........RQRRQMTRDLRTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEED...
A0A139NED4_9STRE/34-94              ..........q-KQEEMVAEIRQLFLDMGVIATLYVELYKSDDSLLEGGVIFEDGRHYSFVYEDGILHYEEE...
A0A239SX18_9STRE/10-78              myldeqreehl---AQVVREVRRLFASMGEIATVYIDQTASDRVQTKGGVVMADGVVYLFEYLAGEIFYQEE...
Q8E223_STRA5/32-92                  ...........YKRQQITQTLREFFSQMGDIQVFYFNEFESDIKMTSGGLVLEDGRIFEFIYRQGVLDYVE-v..
A0A139NHZ1_9STRE/24-82              ...........KQQARLLAQVRAHFPAQ-EISVVYVNPQE-TAGDFSGGLVLTDGTVWQFALGEDGLTVEEE...
A8AZF5_STRGC/34-94                  ...........KKREEIINLVRSFFASQGQIATVYVQLYESNEDKLVGGVVLEDDRHITFVYENGQLTYEEE...
F9HJH9_9STRE/34-94                  ...........KKREEIVELVRNFFASQGKIATVYVQLYESNNDRLVGGVVLEDDRHFTFVYEMGQLSYEEE...
A0A380KXS6_9STRE/34-94              .........ad--REEIVQVVRDFFADMGEIATVYVQLYESSDERLVGGVVFEDERHFTFLYENGELSYEE-a..
Q8CYB9_STRR6/37-97                  ...........KTQEELTEIVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEE...
A0A4Y9FJ31_9STRE/37-97              ..........r-SQEEMTATVRAFFSEMGRVETLYVELYHSDQDCLAGGVFLEDGRHFRFWLVGEQLDIEE-v..
T1ZHM4_STRIT/34-94                  ..........e-QRERLVAEIRESLSEWGPIATLYVQLYKSDEHRLVGGVVYEDDRHISFVYENGELIYEEE...
A0A4R0QQZ4_9STRE/32-92              ..........v-KKAQALAHVRRFFADFGTIATVFVYENDSNARQLTGGVVMEGGPVYLFDYQNGQIVYEEE...
A0A3L9DRX1_9STRE/32-93              ..........k-ERQQILMEVREFFESFGTISVVYVNDFESIRRLVTGGVVFEDGVTFYFSYDHGDINYR--lee
E1M8M9_9STRE/22-82                  ...........KTQEELTAIVRDYFSEMGEIGTLYVQVYESSLERLVGGVIFEDGRHYTFVYEDEDLIYEEE...
A0A3L8GS41_STRIN/32-92              ...........KKKERCIRDLRHFFSEMGTIDVLYFDHSGAASSHHQGGLVLSDGRCFSFTYDKGEIVYQED...
A5MA37_STREE/29-89                  ...........KTQEELTAIVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEE...
Q8DS63_STRMU/34-94                  ...........RKRERIKAELRQFFNQLGEIAVLYVNEFESDKDTIRGGLVMNDETIYLFTYENGQISYEED...
A3CKG6_STRSV/34-94                  ...........RNREEIVELVRDFFSSQGTISCLYVKLYESTDDRLVGGLVLEDDRHFAFVYENGQLSYEEE...
G5JND5_STRCG/53-113                 ...........RKQARIVAEIRAYFSKMGDIQVLYIKDYETQGASLSGGLVFEDGRVLDFIYDDGHISYSE-g..
#=GC seq_cons                       ...........+p+cclltplRpaFuphGpIuslYVp.a-SspcplsGGVVhEDGRpapFsYcsGplsYEEE...
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