GenomeNet

Database: Pfam
Entry: DUF4763
LinkDB: DUF4763
Original site: DUF4763 
#=GF ID   DUF4763
#=GF AC   PF15960.7
#=GF DE   Domain of unknown function (DUF4763)
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   Jackhmmer:Q4V3S3
#=GF GA   30.10 30.10;
#=GF TC   30.60 32.60;
#=GF NC   28.40 30.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR031883;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins is functionally uncharacterised. This
#=GF CC   family of proteins is found in bacteria and eukaryotes. Proteins
#=GF CC   in this family are typically between 237 and 332 amino acids in
#=GF CC   length. There are two completely conserved residues (C and R)
#=GF CC   that may be functionally important.
#=GF SQ   51
#=GS A0A6I8V651_DROPS/75-299   AC A0A6I8V651.1
#=GS A0A0P8XZ18_DROAN/25-281   AC A0A0P8XZ18.1
#=GS B4LER4_DROVI/3-226        AC B4LER4.1
#=GS B4N913_DROWI/42-300       AC B4N913.1
#=GS A0A3B0KA23_DROGU/80-303   AC A0A3B0KA23.1
#=GS B4M583_DROVI/12-266       AC B4M583.1
#=GS A0A0Q9X3T0_DROWI/35-311   AC A0A0Q9X3T0.1
#=GS B4NDJ5_DROWI/27-271       AC B4NDJ5.1
#=GS A0A3B0J299_DROGU/7-233    AC A0A3B0J299.1
#=GS A0A0Q9WUF3_DROWI/1-209    AC A0A0Q9WUF3.1
#=GS B3MHP8_DROAN/8-234        AC B3MHP8.1
#=GS A0A4W6FS19_LATCA/261-411  AC A0A4W6FS19.1
#=GS B4J3Y8_DROGR/141-364      AC B4J3Y8.1
#=GS B4JMS4_DROGR/91-325       AC B4JMS4.1
#=GS Q9VI34_DROME/16-274       AC Q9VI34.1
#=GS B4KU27_DROMO/14-239       AC B4KU27.2
#=GS B4N6T2_DROWI/3-220        AC B4N6T2.1
#=GS A0A6I8USS3_DROPS/7-231    AC A0A6I8USS3.1
#=GS A0A4W6FRK8_LATCA/237-387  AC A0A4W6FRK8.1
#=GS A0A484BS62_DRONA/14-239   AC A0A484BS62.1
#=GS A0A3B0JUZ8_DROGU/39-308   AC A0A3B0JUZ8.1
#=GS B4KDF8_DROMO/14-281       AC B4KDF8.1
#=GS Q9VBH0_DROME/141-297      AC Q9VBH0.2
#=GS B4QYC6_DROSI/16-286       AC B4QYC6.1
#=GS B4HLT8_DROSE/3-237        AC B4HLT8.1
#=GS Q9VT87_DROME/3-237        AC Q9VT87.2
#=GS B4M755_DROVI/2-224        AC B4M755.1
#=GS B4M9X1_DROVI/88-322       AC B4M9X1.1
#=GS B4JUK0_DROGR/10-270       AC B4JUK0.1
#=GS B4GEQ8_DROPE/39-317       AC B4GEQ8.1
#=GS Q9VYI7_DROME/6-254        AC Q9VYI7.2
#=GS B3M0W5_DROAN/12-279       AC B3M0W5.1
#=GS B4HQQ0_DROSE/9-228        AC B4HQQ0.1
#=GS B4ICJ9_DROSE/81-317       AC B4ICJ9.1
#=GS A0A0L0CAS4_LUCCU/14-245   AC A0A0L0CAS4.1
#=GS B4GCL6_DROPE/7-231        AC B4GCL6.1
#=GS A0A0P9A0L4_DROAN/89-312   AC A0A0P9A0L4.1
#=GS Q7KVW9_DROME/44-300       AC Q7KVW9.1
#=GS B4I4H5_DROSE/16-286       AC B4I4H5.1
#=GS B3M5J4_DROAN/5-249        AC B3M5J4.1
#=GS Q4V3S3_DROME/9-228        AC Q4V3S3.1
#=GS B4MFE0_DROVI/14-237       AC B4MFE0.2
#=GS B4L553_DROMO/87-318       AC B4L553.1
#=GS B4QDV8_DROSI/9-228        AC B4QDV8.1
#=GS B4QNT5_DROSI/3-237        AC B4QNT5.1
#=GS B3M5B7_DROAN/3-224        AC B3M5B7.1
#=GS B4IGK0_DROSE/7-255        AC B4IGK0.1
#=GS A0A484AWJ2_DRONA/87-335   AC A0A484AWJ2.1
#=GS A0A484BDK9_DRONA/14-284   AC A0A484BDK9.1
#=GS B4MPX2_DROWI/7-240        AC B4MPX2.1
#=GS A0A6I8UQK9_DROPS/39-315   AC A0A6I8UQK9.1
A0A6I8V651_DROPS/75-299              .................................................CIIRRIELMQLAIRQ........................................RQNQ-----------AISEDQTAPEEE-..QQPEEEYLTKIQQLCQEIERKRKE.L.DVKVEVQ--.............-----........ELMPERPKPLELS..CQEKVEVRDLQHAHHR....LQCEISEMICRYQNLRATLRDFRLRMCSINKQLRHMSARAQEFNEWV.LQVAGELHVCLERYHYLLHQKISKIEAQ.TTAKVHIFRFFS......LNKQFLMNSRLPRDLRDLRFEIDELCIFIN.DLTEEMEERFDKVEH-s.................
A0A0P8XZ18_DROAN/25-281              .................................................CTAPGLPKYEIEKKYrhlecplqkav..................kknyipsprpkIVVSCEPSE----HEEIFPEDEESTKP-..VSERSMNLKDILEEVKLIKRRVNR.L.NHLLKTDVA.............ECPTI........KTCYDDLMS-QLY..E-ASPLILELQINSHK....LDIQLPQLLSARECTEMNLKMNRDALCRDKKIADALLKRLGNLDSFQ.RTMEKEQALCLERYRHVDREKLDGMEFD.RDSEKWERLTAY......QILNVANKNNYQKTKRLVFKQINHLKQSSK.ELHFILIKEMN-----iar...............
B4LER4_DROVI/3-226                   .................................................CRAAGLPG-------........................................-----TPST------TMSTFETFTEELN.iEEQSQLNLDEIYDQLEQMKQRALQ.L.RKILV---R.............EQPAA........AEYAKCLKDIELN..GSQNVALHQVQLQTAK....IVGQVLNLSLRLKSEGKHLKNLDCDLQHQKKQTQALEIKIEKLHKWP.SQQQHRAGLCLDRYSDLSIRCCSVDDYR.RFMEDLYTHYEY......RYKIIMPLKCYKADRVHVAKRLKKARQMLS.DSSQVLLQHSNELGQ-i.................
B4N913_DROWI/42-300                  .................................................CKAKGIPICEPEKEEvadvkvist.....................yfelprvkkaKLFQCPQSDSIELIEAISEESEIPA---..TLDEELQIDDIQNEVDRMKLKVSQ.I.NLLLGLNTP.............ECPSI........DPCLDVDTELKKH..L-ISPEILNLQRNNQK....LQQQISQLQLCRKASDLSMNNLTESISADRAAAGNLKKRLGELDSLK.RTLEHEQALCGQRYRYMEKDKYDGSDLH.PLFASANVNIKR......VISKLVPTREYEKQKVQEIKKIQYLNEQCR.KLFDYMLESFDKLDA-k.................
A0A3B0KA23_DROGU/80-303              .................................................CLIQRIELMQLAIRH........................................-----RPNE--DMSEKRMAEEEKQQ---..EEEYLTRFQLICKEVEG-KRKQLG.V.KIEVAEPKP.............EQP--........-------HPLELT..CQEKLEVRRLQHAYHR....LQCEISDLISSYQKLRSIPRTFRLHLCAMNKQLRLMSTRVQGFNKWT.KQVHSEIRECLERYQHLMHHKISKIEAQ.KTAKVHIYRFFA......RNKFFLMKSRMPREVRDFRGEIDDLCSFIT.DLSVEMEQRFDKFEQ-s.................
B4M583_DROVI/12-266                  .................................................CKAPGLPICELEDSSsnvevvdnl.....................sigqpepgrtLLCDC--------VKKASEEEEPSLEQS.tTVDEELQLEDIQDELEKNRALVDL.I.GQRLSLNIP.............DCPEL........DACMDMQVELNKD..G-MHPEILKLHRNNSQ....LRQQLSQLQHSCKAVDLSLKYMHNSLCRDLEAGAAMQRRLNELDSFK.RIAEHEHALCRQRYRHLEQDKFDWNDCF.AYISKHYMELQP......LLKKYVRRTEYGQLRQDASELLNQAKLEAK.ELHDYLAENMNTLSQR..................
A0A0Q9X3T0_DROWI/35-311              .rcrkieifdyeeelsfsaeeeegegltfstedatddeeralrlvqeidCLIHRIQLIQLTIKK........................................RQEEQKQKS------------EEAEVKE.vELEEELPIPSKLARCLRQREMLEE.NnNNEIETNLV.............EEP--........---KSKVNNLKLS..CQEQKEVNDLMHAHDR....LQCELDEMICRYQNLRHVFQEMRLQLSTLEKKLRQLQDHAKDHIEWT.KQVAGELNVCSQRFKYLNKVKLSKQNAA.RVIASKVAFAFN......QKMTYLQDNQYKYDLKDYNKEIAEMCCHLE.DLRSEIEYRCDKLER-n.................
B4NDJ5_DROWI/27-271                  .......................lisrtlkceqeifhydeklsftptds---------------........................................------------QGDGAEEEEILIPTTE.dGTDDEDHLNQTLNALDCLIQRIEQ.T.QFEVEKRKE.............KKLKE........TAAAFFSLDDPID..CEDELQISNLEHAHHN....LQCEIDRVHLYYRELSHALMDSMKMMCQLEKQIILLDDIALDYKEWAdETADLELNVCPRRHKELNNTMITKKEIK.TVTKGYEESAFK......RSYKCVKKHQVTDEISKFYLAMDEMMQLTD.DLKAEMEKRYAKLEE-l.................
A0A3B0J299_DROGU/7-233               .................................................CRAPGLQQ-------........................................----QEQSE------EILSSGTEPTASV.gEEEQQLDLEALYDELEAWKQRLWQ.L.RSKLVVSPK.............QPCE-........AQAALEDTDESFL..TIESRQLVALRRQNCV....LRCQLQSMAAHLKDSRKELKEMDAWRCLLTTRIQRLRKELDVFGEFQ.LRAIHHFGLCIERWEQHKACKVENNVYR.RRMRELIQHIDG......SRVQLVPMHCHRQTSQHLRSEIVQTRIFLH.NLYESMLAHLRFFHR-q.................
A0A0Q9WUF3_DROWI/1-209               ..........................................ddqgekg---------------........................................----------------------------..VEEKILDLQQLAQEISVMHDELDQ.I.QDRLHISVP.............RCPEIl......pVTCANEQWVQLYG..S-KQPDIKKLQLQTKH....LEYQLNELRKCSQISRFRIERLENRHYGQKKSLFDLQNTYNWIRSKY.LQMEQNHGKCLQRYRHNRTIFATWTEVH.QAADELKSIYKK......FLDQMYDKPTYCIQKKFILREINLLNSRCV.GAIQVTLMNGKEL---eqr...............
B3MHP8_DROAN/8-234                   .................................................CRAPGLPEIEP----........................................-----EEEE-----SELLSSGPEPT---..VGEEMEDLDGAYDELELIKQRLLQ.L.RDTLLPPQR.............DKCYI........QQEEQEREDTSFK..TQESLQLIELRRQNCQ....MRCKLSTAYEHLNSSRKQIKELEGWRCLLQSRIQKMSHQLTKFGEFK.IRAIHHFGLCIERWEQQKTTKVDHVTYR.NRMQSVVSHADN......SRQCLVPLHCHKATRQHIRLELMLLRVFLH.NLFEAMVNDFRFFCR-q.................
A0A4W6FS19_LATCA/261-411             ....................................dgspsgdsagqpa---------------........................................-----------------QDSQTSPA--E.gNSMLEIRLRKLVDEREKMIEQVKK.L.KAQLEQKSP.............KNGS-........ESSSSPDGEIVEN..G-NDPNIIELQRDSNRqisdYKFKLVKAEQEVTALEQNVTRLEGQVTRYKSAAENAEKVEDELKAEK.RKLQREVELC------------------.------------......------------------------------.----------------f.................
B4J3Y8_DROGR/141-364                 .................................................CSAPGVLS-------........................................------TDE-----DEILSASGSIE---..DAEEEPDLDLAYDQLEAIMQRLKH.L.RGKLLLSPA.............DPCEL.......eLGTLSEAEDTCCL..TPNQLMLQQLRHRNCM....LRCQLQRQAQHLHSSRKQLKLLESMRCQLNDRLQKMSAELNAFDQFK.MSAQHQFGLCIERNEQIKASKIDEFDFR.RHVRDVITQCHD......KMSPLVPMRCHRQIRNNFSVELLLIRVFLH.TLFSNMVEDWSYCKKR..................
B4JMS4_DROGR/91-325                  .................................................CLIRRIQQMQLIIKQ........................................RKQDQQQLDTTEVSTEQQEEEEVIKQPP.iPQLGKFLFQECMEQTLE-ETKLDI.L.KRELK----.............-----........AEMKPDSKFNSLS..CDEQLEIRDLRHAHHR....LQCEIDEMVCNACTMRELLLKIRNQVGQDKKRLLKLAAIATKHHEWS.NLIYKELPVCKQRYQYLLEKKLSKSEAH.RLIHAHMVKVIH......YNKKFLTRRELRYELREFHLEIDELEKYVN.DLRQDMVRRFSSIEN-e.................
Q9VI34_DROME/16-274                  .................................................CKAAGISKMENTKPNdkklaqskfaf..................khngpkkvfhcTMQSVLQSEDCWIAEEVLEES-------..NEKSNLELEDIYDEVFRLKRRVNR.L.NYQLGTNIP.............ECPKI........DPCLDDHIFLTNV..KEVHPEILQLKFASHK....LQHQLTQMQSVRRSSNLAKKLVRDEYCRSKKLGDQLQIEIQKLDSFK.LKFEKHQGLCLQRFRFLDQDKYTGREFY.EFIEKSNEMITT......QLKKQMLKSEYKPFRKEAARVTISLKTAAE.NLQDYLSSVINNKKC-e.................
B4KU27_DROMO/14-239                  .................................................CQAAGVI--------........................................-----SPEE-----SEILSSSDFDDET-..VSAEEPDLNLPYQQLEAIKQRLKK.M.RAKLIYTPP.............DPCEQ.......eDDGVSAGEQADFL..NQKQLQLQQLRRSNCL....LRCQLQSRVQHLHRARKELLLVENMRCQLNKMLEKMVTEMNILEEFK.VSVQHHFGLCIERNEQIKMSKIDCHDFS.ELVHDKTIRRMG......HMRPLVPLRCHLQVRYNLNVELILLRVFLQ.SLFGNITEDWKLFNR-i.................
B4N6T2_DROWI/3-220                   .................................................CRAPGLFEK------........................................---VVTPTT-------------EEDVVE.eESSSSPDLETISNKLEQMKQRALL.L.RQSLVHDTV.............QKP--........---DEPNIMPEEN..LSKHLEIKQLQQQNAK....LISQVTDISERLKCQWDKLSGLESQLLNLRSTTNGMAEKINAISKWK.TTTQHMAGLCIERYNDLKISCCTSPEFG.AYYRGLSADFDH......DLKVRVPEKCYRKDQQQITQRLNNTKQMIR.TSTDLLLHHCNQLEQ-f.................
A0A6I8USS3_DROPS/7-231               .................................................CRAPGLQ--------........................................------QEE-----SEILTSGPEPACTG.gEEEEQLDLDALYDELEALKQRLLL.L.RSKLVTSPK.............DQCQ-........AQAAMEDTDESFF..TAQSRQLVALRRQNCV....LRCQLQSMAGHLNSSRKELKEMDGWRCLVATRIQRMRRELDTFEEFK.VQAIHHFGLCIERWEQHKACKVDSNVYQ.RRMRELIQHIDG......RRVQMVPMHCHHQTFQQVRMEIIQTRLFLY.NLFDSMLCYFHFFNR-q.................
A0A4W6FRK8_LATCA/237-387             ....................................dgspsgdsagqpa---------------........................................-----------------QDSQTSPA--E.gNSMLEIRLRKLVDEREKMIEQVKK.L.KAQLEQKSP.............KNGS-........ESSSSPDGEIVEN..G-NDPNIIELQRDSNRqisdYKFKLVKAEQEVTALEQNVTRLEGQVTRYKSAAENAEKVEDELKAEK.RKLQREVELC------------------.------------......------------------------------.----------------f.................
A0A484BS62_DRONA/14-239              .................................................CQAAGVI--------........................................-----SPEE-----SEILSSSGIVDET-..VSTEEPDLDLPYQQLEAIKQRLKE.M.RAKLIYTPA.............DPCEQ.......eDDGTPPGEPADFL..TQKQIQLQQLRRSNCL....LRCQLQSRVQHLHRARKELLLVENMRCQLNKMLDKMVNEMNILEEFK.VSTQHHFGLCIERSEQIKMSKIDTHDFG.ELLNEKTLRMMG......RVRPLVPLRCHLHVRYNLNVELILLRIFLQ.SLFGKFSEDWKLC---mri...............
A0A3B0JUZ8_DROGU/39-308              .................................................CRAPGLVRCVPEAHVpsaetlwkfidlplvkk......tkifhcepppepshpkrKGSEITQEE---EEEEQTSEQSSPS---..TLDEEMQLEDILAEVNRIKGRVGE.V.DRLLGTRIP.............ECPDI........DPCVNMDVELLAF..N-TNPDIVELQRNTHK....LRQQLVELQMCRVATDRNIKDIRLSICQEMEHADHLQKSLNELDSFK.RTLEREQALCRQRFRFVEQEKVDGGECN.TYFDTERNLMEC......YLDKLVTRLDYQQQKRRALKDIDYMKLKAK.RFHDHMFYAIGKLN--a.................
B4KDF8_DROMO/14-281                  .................................................CRAPGLPNCEPEDTHisvveqvsfrki................eppippktlhcdSIDRVDELEDADVEGEEEEEQEASASQS.tKPEELVELEQIEAELLEQKNAVDL.I.GEEIALDMP.............ECPSD........DSCVNMELELQRG..K-VHPHIYKLQQENHL....LRQQLSKAQLSCKAIDLSLKYLRNSLCRDLKAGAILRRRLDELNSFK.LNVEHEQVLCRQRYNHLQEVKYDWVDCK.AYLKESAEYTQR......EIKKIVRRADYTQPHLDALKLLKGAKRMAM.DLHFDLTNRMTRLGQR..................
Q9VBH0_DROME/141-297                 .......................................cpnnqplcgn---------------........................................----------------------------..------------------------.-.---------.............-----........-------------..--ELLEARSLRQAHNR....IQLQIDELICRYRKLREIIHQMRERIRCMEGNLIDLNSEAVKYVAWS.SEVSKELKLCQERYNYLVNAKMSKADAK.KLDHAHTTRFLK......QNAACLSKSRLKREIADFNGEVKDLVNLMS.ELHKELDRNMAVFES-r.................
B4QYC6_DROSI/16-286                  .................................................CKAAGISNISKAAEIskientkpkdkklaqpk......hlkfaftepgpkkvfhcMEQSVLQSEDCWSAEEVLEES-------..DEKSNLELEDIYDEVFRLKRRVNQ.L.NYELGTNIQ.............ECPNI........HPCQDDHIYLMNV..DGVHPDILQLKFASHK....LEHQLTQMQSVRRTSNLAKKLVRDDYCRSRKLGDQLQIEIQKLDSFK.LKFEKHQGLCLQRFRFLEQDKYTGREFN.KYIEKSNEMKRT......QLKKQVLKSEYKPFRKEASRVTISLKKAAE.NLQDYLTSVINNKKC-e.................
B4HLT8_DROSE/3-237                   .................................................CKAPGLLE-------........................................-----TPSESELTHCSISALDNIPIQEE..ECPSELELSKPFNKLEKMRERVLY.M.KSLLIRPVQvn.........kaECP--........SESDQMRLDIEQS..SSDNDELRVVQQDTVR....ALQQIIEVNRQLKETTDSLTGLDEKARKNIRCIRKLSKRLLEVPKWK.EELKHNTGLCLERYNDLDISRGNYLDYSdNFVRPIQTNMKF......CFASKAPLICNKHDYNDLVNALSKSRRTLL.KCHEELMKYTQKVDE-a.................
Q9VT87_DROME/3-237                   .................................................CKAPGLLE-------........................................-----TPSESELTHCSISALDNIPIQEE..ECPSELELSKTFDKLERMRERVLY.L.KSLLIHPVQvn.........kvECP--........PESDQMRLDIEQS..SSDNDELRVVQQDTVR....ALQQIIDVNRQLKETTDSLTGLDEKARKNIRCIRKLSKRLLEVPKWK.EELKHNTGLCLERYNDLDISRGNYLDYSdNFVRPIQTNMKF......CFASKAPLICNKQDYNDLVSALSKSRKTLL.KCHGELLKYTQKVDE-a.................
B4M755_DROVI/2-224                   ............................................evhsw---------------........................................------------NSSSGNSATSASNTDS.lLEPTEPEVQQIAAELELMKGYLDN.L.ELQLKTGVP.............ACPPR........LPVDCANIEPDLK..DSSDANIRQLQRNVYK....LEHQIAELFACSDMAKDMLTVLGCSFCQLQRDMRDARQQYDAVESIK.LQTDHQASLCLQRYTHLCHMFANWSDSK.ENAKEMQSVFLN......YVESMHTKAAYLAEKHIRYKQLEEAENICM.LATKQLIRQAKDVE--dy................
B4M9X1_DROVI/88-322                  .................................................CLIRRIEQMQLVIKQ........................................RKEAQMELDISDYSTEQEPETSAT---P.iPELGVFEFKQCRVKSAKIKKDSSP.D.QEKLADK--.............-----........ELPLPDAQKDPLN..CEEQLEVRNLQHAHHQ....LQCEIDELICNYRLMRGLLNKMRNQLCQENRRVRKLGSITHQYQDWS.RLVAEELPVCKQRYNQLIEIKLSKAEAN.RVISAHKAKAMR......YSNTFLTSRQLRYELREFHSEIEELKEYAS.DLRKEMIRRFSSIEH-e.................
B4JUK0_DROGR/10-270                  .................................................CRAAGLPLCEPESSTsvdevhpfr.....................kilspqpaktLLCDC--VFGDDGDDDEGGESELSLEQP.lTEGDDLQLEDIQDELDKKKAFVDL.I.GKRLSLQVP.............DCPIG........DVCVDKQLELNNF..D-THPEILELQRNNHK....LSLQIRALQHSCTATDASLKHLRMLLDRELEAAVVLQRRLDRLDSVR.RTMEHEQALCRQRYRHLQEDKYEWQDCH.AYIKRSREEASL......ELVKFVPRLEYIQPKHDAVQLLNQTKRLGK.ELHEFLVENMARLS--lr................
B4GEQ8_DROPE/39-317                  .................................................CNAPGLMRCVPKVEVppaetlwkfiappwvpktklfhceppppptptptpgrsrrKGSQISQVSQMDVEEEQSSDQSSPP---..TMVEEMQLEEILAEVKRIKERVGE.V.DRQLGTRIP.............ECPDI........DPCVDMDVELLAF..N-TSPDILELQRNSHK....LRQQLAELQLCRVATDSNVKAIRESICREMENANRLQKLLNELDSFK.RKLEREQALCRQRFRYVEQVKVDGAECN.NYFSSERKLMEY......FVGKLVTKADYQQQKRRALKEIDFLKLKAK.KFHDHLFYATDKLD--a.................
Q9VYI7_DROME/6-254                   ................................ktqsmkrknelfhhdcv---------------........................................--------S--DIDGSVSDGSEELEEQS.pEQIEEIAWPQMKREIGAMNRTLDE.I.QAQLAIDFHerdg....grscwE---EeqealakgLEPEDSRWMIM-H..GSREAALRELQWNNLR....IRRQLADLVRCSELGRARISALDRLFQRQTKELVGCRQDHERVLSFH.LTKQLEAGKCLQRYRYARDLYASWRELF.KMGRHLKEAYKK......ILERTQSRLEYAEIKRQALDEMTVAHEMCL.GSTRSLLARVRDLE--l.................
B3M0W5_DROAN/12-279                  .................................................CRAAGLPSKEAPVPIivegkpkfigk..................kkevteirvknELFHC-DADGLSNLDELSGEVGDSTEW-..TTPRWFQLDEIQKELSGLKLRVSH.L.NGKFRLGVP.............KCPDI........ESCTDIGLEARNI..D-THPDILDLQRNSQK....LVQQQAQLEQVKRASDQAITLLKNSISQNMCFVNSMQGSFGKLDCFE.RNLEWDQALCLQRFCSLNHRKLS-NDFS.NLNNSVTFEMEEpcalklSLEKLITIKEYTGKKKLATQVIFQLKSGAI.NLLDCMTMRIHTLDDR..................
B4HQQ0_DROSE/9-228                   .................................................CRAPGLPKLE-----........................................-----EQEE-----RDLLSSGIDSS---..DAEEETDLDAAYDELEEMKQRLIA.L.RNKIIITNP.............DAC--........----QDLKVRELW..STEGGELQELRDQKCQ....LICQLQEVTQHLKDSQNELKELEGWRCHLQSRIHQAKRQLSQFEDFK.LKVIHQFGLCLERWENQKTCKVDYTTYR.KEMEAHILHADN......VRQSVVHQKCHKSYRRRIRVELMLIRVFLH.NLFEAMVNDFKFFSR-h.................
B4ICJ9_DROSE/81-317                  emetldrseqsddrpvkmaqdidclirqiesmqiairkrqvkkcsedis---------------........................................----------------------------..EETAENEIEAIADAQVKCKQRENQgI.DIEIKKK--.............-----........-SVAICSNNQPLC..GNELLEARSLRQGHNS....IQMQIDELICRYRKLREIIHQMRESIRCMEGNLIDLNSEAEKYVAWS.REVSKELKVCQERYNYLVSAKMSKAEGK.KQDLVQTTRFLK......YNAACLTKSRLKREIADFNGEVKDL-----.----------------vnlmmakgsmnsmsr...
A0A0L0CAS4_LUCCU/14-245              ......................................rtlccnpirek---------------........................................------ENEIEIFESEATEFEEDAEELI.vSEDEKLDIKQLMEDLDCMKRRIQL.I.QLRLKLPTD.............ECPE-........EECLDYEVLLNCS..K--NKEICTLQKNQHM....LQHQIKELVKCNKIAKEQIKVLQLNMCEKNNEILELRELVKTLMEWK.NTLDHEFGKCLERFEYLKHVKAEWRDVN.EKIEEQNKCLST......FKESFVGKACFLQEKKSFIDAINEIKEMLK.ELFQYQFERFASLEQR..................
B4GCL6_DROPE/7-231                   .................................................CRAPGLQ--------........................................------QEE-----SEILTSGPEPACTG.gEEEEQLDLDALYDELEALKQRLLL.L.RSKLVTSPK.............DQCQ-........AQAAMEDTDESFF..TAQSRQLVALRRQNCV....LRCQLQSMAGHLNSSRKELKEMDGWRCLVATRIQRMRRELDTFEEFK.VQAIHHFGLCIERWEQHKACKVDSNVYQ.RRMRELIQHIDG......RRVQMVPMHCHHQTFQQVRMEIIQTRLFLY.NLFDSMLCYFHFFNR-q.................
A0A0P9A0L4_DROAN/89-312              .................................................CLIRRIEHMQLAIKK........................................RQMEA--------STETESEEAQPE---..-----DEAEEIITKLQRRCRKLEE.R.RQDLESTIK.............---ST........AAQSKKSKVKQLS..CDEQIEARNLRHAHHR....LQCEIDEIICRYRELREILTQMRGHLCTMEHTLRKLSKQSEEFLEWT.QQVSAELNVCKERYTYLINAKISKRESS.TTGHRHAIRFAK......RNAAYLSKNRMKRELTEFKEEVNELVGFMG.ELHKELERNL------amfgy.............
Q7KVW9_DROME/44-300                  .........artttkcqlggeqmispgyqrlgpsldrvpddeetdsqee---------------........................................-------------EMEILPCGMGEE--GitTDEETKTLITIQG-LDEILKRIDI.L.RSQLRRNQQle.........diSQP--........SVMPEDPISCSGL..NAKQSEIRCIQRAQHH....IQCQLTELLCRYDALRNMLRSLGETWTCLERRIADIRGQNRVHLAWT.EECANDLSNCQQRHRSLAAVKLTKKMAL.LVTKTNMSSGFR......YSRRYLRHALIARHINDFRYEIAELKVLSE.EIFSEIDGRL------dqikmk............
B4I4H5_DROSE/16-286                  .................................................CKAEGINNICKVAEIskientkpkdkklaqpk......hlkfaftepgpkkvfhcTEQSVLQSEDCWSAEEVLEES-------..DEKSNLELEDIYDEVFRLKRRVNQ.L.NYQLGTNIP.............ECPNI........HPCQDDHIYLMNV..EGVHPDILQLKFASHK....LEHQLTQMQSVRRTSNLAKKLVRDDYCRSRKLGDQLQIEIQKLDSFK.LKFEKHQGLCLQRFRFLEQDKYTGREFN.KYIEKSNEMIRT......QLKKQVLKSEYKPFRKEASRVTISLKKAAE.NLQDYQSSVINNKK--ce................
B3M5J4_DROAN/5-249                   .......................ktkkyqtkvakifycdedksekasgk---------------........................................-----------NVEKA--TENQDPVDPE.sWSKSSKDLDEINLELKDINRSIDQ.I.EARLCRDPRq...........iGCFET........EKCVEDDDDQWMLvyGSRDERIRQIQWNSRH....IRRQMSGLEECATIATARISALEQLFLDQTSHLSELRRLYEVVRSFH.LTKELEAMKCLQRYRYARGQFASWWDIS.RLGHFLIDSFKL......LVDRTESRRSYLERKRHVIEQISATNEFCMaQCREAL----------lsvrqld...........
Q4V3S3_DROME/9-228                   .................................................CRAPGIPKLD-----........................................-----EQEE-----SDLVSSGIDPS---..DAEEETDLDAAYDELEEMKQRLIT.L.RNKIIITNP.............DAC--........----QDLKIRDLW..TPEGGELQELRDQKCQ....LICQLQEATQHLKDSQNELKELETWRCHLQLRIHQAKRQLSQFENFK.LKVIHQFGLCIERWENQKTCKLDCTTYR.KEMAAHILHADN......SRKSVVYQKCHKSYRRRIRVELMLVRVFLH.NLFEAMVNDFRFFSR-h.................
B4MFE0_DROVI/14-237                  .................................................CRAPGLL--------........................................-----SPVE-----SEILSASDKVE---..FGEEEPDLDLAYDQLEAIKRRLKQ.L.QANLIYPPA.............DPCEL.......tGTSRTASEDNGSL..TDNQVMLQQLRRSNSK....LRCQLRLQAQHLQSSRKHLRLLEDMRCQLGNRLRQMSAQLDEFEQFK.RSAQHQAGLCIERNEQIKATKIDKQNFL.TQLSKLNIHYTN......HMRLMAPLRCHNQLRYDLSLDLILTRIFLH.ALFGNMVEDWKFCIR-r.................
B4L553_DROMO/87-318                  .................................................CLIRRIEHMQLAIKH........................................RQDYVRGSDMSYPTTELESSSATPV---..PELGVFEFKECMP--VKVKRVLSP.Y.QQQLAAN--.............-----........ELPMDEPFHIVLN..RMEELAVRNLQHAQHR....LQCEIDELLCNYRLMRTLLGKMRRQICQENRRVRKLGVITQQYKEWS.QEVVKDLPACKQNFAVMVQKKLCKHEGR.CIIRAHKAKEAE......FMRTLLSYRQLNYEIREFELEIKELQQYCN.DLNREMVMRFDILEEE..................
B4QDV8_DROSI/9-228                   .................................................CRAPGLPKLD-----........................................-----EQEE-----SDLLSSGIDSS---..DAEEETDLDAAYDELEEMKQRLIA.L.RNKIIITNP.............DAC--........----KDLKVRELW..STEGAELQELRDQKCQ....LICRLQEVTQHLKDSQNELKELEGWRCHLQSRIHQAKRQLSQFEDFK.LKVIHQFGLCLERWENQKTCKVDYTTYR.KEMEAHILHADN......VRQSVVHQKCHKSYRRRIRVELMLIRVFLH.NLFEAMVNDFKFFSR-q.................
B4QNT5_DROSI/3-237                   .................................................CKAPGLLE-------........................................-----TPSESELTHCSISVLDNIPIQEE..ECPSELELSKTFNKLEKMRERVLY.L.KSLLIRPVQvk.........kaECP--........SESDQMRLDIEQS..SSDNDELRVVQQDTVR....ALQQIIEVNRQLKETTDSLSGLDEKARKNIRCIRKLSKRLLEVPKWK.EELKHNTGLCLERYNDLDISRGNYLDYSdNFVRPIQTNMKF......CFASKAPLICNKHDYNDLVSTLSKSRRTLL.KCHEELMKYTQKVDE-a.................
B3M5B7_DROAN/3-224                   .................................................CRAPGLLT-------........................................-----SGSE-----LNISDLDGLENQYA.eESNNEVDLDEEYDKLEKLKQRVLH.L.RGLVAGPL-.............-----........QPHEELHGLSLDG..VSKNPELQKAQVKTMR....AKARVAKLSWRLKGDRKILRRFNAELLCHLQCSGKLLEKMGEPMKWR.PQHEHYKELCRERYSQLDISLCNYLGYS.DRMRPIQTKLFR......AFHVKIPMFYYRRDFRNISMSLGRIQSTIR.FCAKRLMAHIREVEE-d.................
B4IGK0_DROSE/7-255                   .................................tqtmkrkievfhhdcv---------------........................................----------SDIDGSVSDGSEELEEQS.pERIEEIAWPQIKREIGAMNRTLDE.M.QAQLANDFHerdggrpdweeehEAAAAk......gLEPEDSRWMIMHG..S-REAALRELQWNNLR....IRRQLGDLVRCSELGRARITALDRVFQRQTKELIACRQDHERVLSFH.LTKQLEAGKCLQRYRYARDLYASWRELF.KMGRHLKEAYKK......ILERTQSRLEYAEVKRQALVEMTVAHEMCL.STTRSLLGRVRDLE--l.................
A0A484AWJ2_DRONA/87-335              .................................................CLIRRIEHMQLAIKH........................................RQDYARGSDMSYATTEQDSSSGTPV---..PELGVIQFKKCIT--RKVKRVLSA.Y.EQQLAAN--.............-----........ELPMDEPFHIVLS..PEEELGVRNLKHAHHR....LQCEIDELLCNYRLVRTLLSKMRRQMCQENRRVRKLVDVMQQCKEWF.LKVVKDLPLCNRRCAVYEKRKVRKFDAR.RIVKSHFAYKGG......IFRTFLSCRQLNYEIREFELEVEELEQYCD.DLFHDITQRLDACEN-eegyeeevesesessesi
A0A484BDK9_DRONA/14-284              .................................................CRAPGLPICEPEDTHisvveqvpykkie.............ppvppktlycdsidRLDELEDADDEAEEGEEEEGDEASGGQS.tKSEELVLLEQIEAELLEKKQAVDR.I.GEEMALDMP.............ECPSE........DSCVNMELELQRG..K-VHPHIYKLQQENHQ....LRQQLSKAQLSCKAIDLSLKYLRNSFCRDLKAAAILQRRLDELNSFK.LNVEHEQALCRQRYRHLEESKYDWVDCK.AYLKENDAHTQR......QIKKFVMRADYTQPKIDAVKLLTRAKRKAM.YVHNALTSRMAKFGQ-w.................
B4MPX2_DROWI/7-240                   .................................................CCALGLPK-------........................................----ILENE-----SEILTVSELPANTS.fNEEEETDLDSIYDELETMKQKLLT.L.RSKLIITPM.............DKCQQkm...ekeEQEEQEDSVDEML..TPVQQQLNTLRRQNCI....LRCQLHEMAKHLYATRKDIEEYKALQCQLTQNLQKFCKELKIFDAFK.ANAIHHFGLCIERWEQHKNSKILAKTFM.DMMCKFRISSTG......MHRGHVTLNCHQQVRNDAIMELVLIRVLLC.HIYETLMDNFNFFARR..................
A0A6I8UQK9_DROPS/39-315              .................................................CNAPGLMRCVPEVEVppaetlwkfiappwvpktk..ifhceppppptptpgrsrrKGSQISQVSQMEAEEEQSSDQSSPP---..TMVEEMQLEEILAEVKRIKERVGE.V.DRQLGTRLP.............ECPDI........DPCVDMDVELLAF..N-TSPDILELQRNSHK....LRQQLAELQLCRVATDSNVKAIRESICREMENANRLQKLLNELDSFK.RKLEREQALCRQRFRYVEQVKVDGAECN.NYFSSERKLMEY......FVGKLVTKADYQQQKRRALKEIDFLKLKAK.KFHDHLFYATDKLD--a.................
#=GC seq_cons                        .................................................CpA.Gl.........................................................-.....pch.spsttst.....ppppphcLcplhsclcphKp+lpp.l.ctpLths...............-ss..........t.s.ptphphphh..s.pp.clppLpcssp+....LppQlscltpphcsscpplptlcpphCp.pcplpphppphpphcpa+.hphp+chuLChpRac.lcpsKhstt-hp.phhcphttphpp......hhpphlspppapppppchhhcltph+.hhp.pLhcphhpphphhpp...................
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