#=GF ID   DUF4903
#=GF AC   PF16246.12
#=GF DE   Domain of unknown function (DUF4903)
#=GF AU   Chang Y;0000-0002-2418-3433
#=GF SE   Jackhmmer JCSG target GS14093A
#=GF GA   27.00 27.00;
#=GF TC   71.50 71.00;
#=GF NC   25.10 19.20;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 8 -E 1000 -Z 90746521 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0116
#=GF DR   INTERPRO; IPR032597;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A small family of uncharacterized proteins around 210 residues
#=GF CC   in length and found in various Bacteroides and Prevotella
#=GF CC   species. The function of this family is unknown.
#=GF SQ   31
#=GS E0NRL4_9BACT/24-151      AC E0NRL4.1
#=GS E6SP54_BACT6/23-212      AC E6SP54.1
#=GS A0A378RP88_MYROD/20-211  AC A0A378RP88.1
#=GS D3ICN4_9BACT/24-211      AC D3ICN4.1
#=GS A0A096ADY8_9BACT/23-217  AC A0A096ADY8.1
#=GS K9EMZ6_9BACE/27-221      AC K9EMZ6.1
#=GS F0IBX5_9FLAO/30-220      AC F0IBX5.1
#=GS E0NRL3_9BACT/1-55        AC E0NRL3.1
#=GS A0A7K1GPR6_9FLAO/20-209  AC A0A7K1GPR6.1
#=GS G1W863_9BACT/25-213      AC G1W863.1
#=GS E6K414_9BACT/23-209      AC E6K414.1
#=GS A0A5C8GLH5_9BACT/23-223  AC A0A5C8GLH5.1
#=GS A0AA40ZU24_9BACT/21-208  AC A0AA40ZU24.1
#=GS I4ZC62_9BACT/24-211      AC I4ZC62.1
#=GS A0A5C8GG23_9BACT/32-226  AC A0A5C8GG23.1
#=GS A0A4Y8VD80_9BACT/8-196   AC A0A4Y8VD80.1
#=GS G6AFR6_9BACT/11-197      AC G6AFR6.1
#=GS U2P4Q4_9BACT/21-207      AC U2P4Q4.1
#=GS A0A099BUL3_9BACT/24-207  AC A0A099BUL3.1
#=GS G5GAY9_9BACT/18-205      AC G5GAY9.1
#=GS I9VG70_BACFG/26-213      AC I9VG70.1
#=GS D3ID34_9BACT/11-197      AC D3ID34.2
#=GS E6MS85_9BACT/30-217      AC E6MS85.1
#=GS D8E004_9BACT/26-214      AC D8E004.1
#=GS D1VY46_9BACT/23-217      AC D1VY46.1
#=GS D1PW39_9BACT/23-223      AC D1PW39.1
#=GS A0A264Y3L7_9BACT/24-212  AC A0A264Y3L7.1
#=GS A0A4R7EMX5_9FLAO/20-209  AC A0A4R7EMX5.1
#=GS D7NCK4_9BACT/25-213      AC D7NCK4.1
#=GS F8NAH8_9BACT/19-206      AC F8NAH8.1
#=GS A0A133YWX3_9BACT/23-217  AC A0A133YWX3.1
E0NRL4_9BACT/24-151                 .......CSSDNENTKKALPEADI.AKAKGLL..NGDIVLSTKAYLKGVDNTLLPTGCPTKFNFTWKEN-...-DIMVLSLPNFKVGKMPFSVTFRCETKFLQLGTWEKDEH.KG.SGWVKF.....EGTD.....GNVSTSA..sDTETKKQ------..-----------------------------------------------------------vaep.............
E6SP54_BACT6/23-212                 .......CSSDEKITKAGASDELV.ASAKSYL..NGEIVLSTQATMNGVNKTLLETGCPTKFKFEWSNTD...TQTFTVALLNFTVGKMGMIINFKCDVKTMQLNTWEKDEY.KG.DSWIKF.....YGEN.....GSCWGVD...TTDGTASTAQGSS..VKGYYNVATHEINFIVDYNMMNVRSECFLQTIDKSRLDNYEAEKAQYEKDLAAYKKEHG.................
A0A378RP88_MYROD/20-211             csttese------VELEEAKENLF.E--QKFK..NKEVIIYTRAFRSNGERTVGEKGMPVKFKFDYDKND...PNKLYFEMPEFQFGYMPLAATISGKLDI--INKYV-DAYpEK.KNWIYFgtrsnKATA.....GSYIYNE..qGERIQYDSSPSAE..VNGYYNPDSNEIFMDINFKLMSVTSISPDQTFDAHPLDQYL------------------vlldgyydthrqidkvr
D3ICN4_9BACT/24-211                 .......CQSDDNLEKKDTSEDLV.AMAHQYL..NGDIILGTHATMNGVNKTLLPQGCPTKFNFRWSETD...KNVLTIRLEDFTVGQMPFSITYYCDVKIIQLNSWEKNEY.KG.DNWIKF.....VGED.....GYLALG-...-KGGQPRPMKGSS..VKGYYNVKTHEINFIVDYNMMNVRSECFLQPIDKARINNYEAELKKYEADLAAYKKEHG.................
A0A096ADY8_9BACT/23-217             .......CSGDEKIEQTPVDAEYA.NKVKEIL..KDSIILRSRAMMATVDKTLLPEGCPLKYYFHWNEGS...DKPLNIQLKNFSVGKMPVQIWFNIDCKITHLNSWEKDEY.KG.NGWVKF.....IGEY.....GSTTYMPnknDNNHEYENGDGGSgyVKGFLNVNTKQIEFSTNFNVMLMQSYVFLQTIDYSKMDTYEKDLAKYEADLAAYKEGHG.................
K9EMZ6_9BACE/27-221                 .......CTADEELTQKPVSDEYI.SIAREIL..QDSIVVNATAMQGTVNKTLLDEGCPLKYYLKWKSET...SDMLNIQLKGFSVGKMPVTIWFSINCKFMQLNTWEKEEY.TG.DGWIKF.....QGTG.....GSTRYTGnqnDEEGSYESGDGGAgsVTGYFNAKTNEIEFVTNFNVMNMSSDVYLQKVDPTRIDRFETDFAQYEKDLAEYKKEHG.................
F0IBX5_9FLAO/30-220                 .......CKKEEQHQEIKQEDNRT.AKVIQQL..NNTVILGQDVKMAGVDKSRLPGGVPTKFRFRWKEV-...EKKMEIQIVKIQPGSMPFAIGMTANATLMELSSWEKNEY.PE.AGWIKL.....FDDK.....GEVTPYL..kDDDPAKPKPDGAV.iLVGFYNVNTQEIEISINYNMMNVVGHVFRQKIDTARLKNFDEEYDAYEEALAEWKLDHG.................
E0NRL3_9BACT/1-55                   .......-----------------.-------..------------------------------------...---------------------------------------.--.------.....----.....-------...-------------..----MNINTGEIEFAVDYNFMGARSECFLQTIDKNRIKNFEQELAKYEKDLAEWKKNHG.................
A0A7K1GPR6_9FLAO/20-209             ......c-STSESEVELEEDKENL.FE-QKFK..NKEVIIYTRAFRSNGERTVGEKGMPVKFKFNYDKND...PNKLYFEMPEFQFGNMPLAATISGKLDI--INKYV-DAYpEK.KNWIYF.....GTRSskataGSYIYNE..qGERIQYDSSPSAE..VNGYYNPDSNEIFMDINFKLMSVTSISPDQTFDEHPLDQYL------------------vlldgyydthrqidk..
G1W863_9BACT/25-213                 .......CSSDEELKRADADINLV.NEAKSFL..QGDIILNTHAFMGNVNKTLLPTGCPTKFNFTWSNTD...PQSFTISLLDFTVGKMGMIINFNCAVKTMQLNSWEKEEY.KG.DGWIKF.....YGEN.....GSVSGE-...DAKGVPSQATGSI..VKGYYNVMTHQINFIVNYNMMNVRSECFLQTIDKNRIKTYEEDFKKYEEDLKKYKEEHG.................
E6K414_9BACT/23-209                 .......CSSDDNLEQKDPNAEYV.DEAKKIL..NGDIVLSTKATMAEVDKTLLPNGCPTKFNFKWEKD-...--SMQLSLNGFTVGNMPLVIYFSCKCKFMQLNSWEKDEY.RG.EGWVKF.....KGKD.....GNVTGDP...KDDSGVQKGSGAG..VDGYLNVKTNQIIFIVNYNMMNVRSECFLQTIDKSRINNFEAEFAQYEKDLAAYKKEHG.................
A0A5C8GLH5_9BACT/23-223             .......CNSDEKINSTPIQDEVIlAKAKELLtkEEFIVLRARAMMGPEDKTRLPEGCPLKYYFSWNTAAgkaDRPLNIKLIKFTVGSMPLTVDFNIHCKFIPLNKWERDEY.KG.DGWIKF.....VGEK.....GDVGYIPnekDEKGIYTDGEGGLgtVVGYLNVDTKEIEFSTNFNVMLMQSFVYRQKIDYSKKLTYEQDFKQYEEDLAKYKKEHG.................
A0AA40ZU24_9BACT/21-208             .......CESDDSLTNEPPAQEYI.DKAKEIL..NGDIVLSTKATMNGVDKTLLESGCPTKFNFSWRED-...-GMMVLDLSDFTVGAMPFAITFRCATQFMNLNSWEQDEY.PD.DGWVKF.....VGTD.....GNVTTSG...DDAADNQQGSGAR..VDGFLNVNTNQMEFIVDYNMMNVRTETFLQTIDKTRIDRFEEEFSQYEKDLEEAKKEQG.................
I4ZC62_9BACT/24-211                 .......CSSDENLEQKDPIEEYF.NEAKNIL..NGEIILSTKATMSGVDKTLLPNGCPTKFSFDWVND-...-KTMKLSLEGFTVGKMPLIVYFSCQCKFMQLNSWEKDEY.KG.DGWIKF.....KGKD.....GSVTGNP...KDDSGVQQGSGAG..VEGYLNVKTNQITFIVDYNMMNVRSECFLQTIDKNRINNYEAEFAQYEKDLAAYKEEHG.................
A0A5C8GG23_9BACT/32-226             .......CSGDEENGKKPVEDNLI.LKAKDIL..KDSIVVRSKAMMGPVDKTLLPEGCPLKYYFSWDLKS...ETPLNIKLKNFSVGNMPVQVWFNIYCRLIPLNSWEKDEY.KG.DGWIKF.....TGVN.....GDVTYTPnqhDVNGEYTDGKGGAgtVIGYLNVNTKQIEFSTNFNVMLMQSFVFLQTIDYSKMDTYEEDFAKYEADLKAYKKEHG.................
A0A4Y8VD80_9BACT/8-196              .......CSSDEEITDADANTELV.KEATNYL..NGEIVLSTNATMNGVNKTLLPEGCPTKFKFEWSKTD...AQTFTISLLDFTVGNMGMIINFKCDVKTMVLNSWEQKEY.TG.DGWIKF.....KGED.....GSVWGT-...DTDGSASSAKGSS..VQGYYNAKTHEIQFIVNYNMMNVRSECFKQTIDKSRLATFDADKAKYEEDLKAYKKEHG.................
G6AFR6_9BACT/11-197                 .......CNSDDNLEQKAPAQEYL.KEAKDIL..SGDIVLSTKATMNTVDKTLLPQGCPTKFNFNWEKD-...--SLRLTLDGFTVGKMPLIVYFSCKCKFMQLNSWEKDEY.KG.DGWIKF.....KGKD.....GSVTGNP...KDDSGVQQGSGAG..VEGYLNVKTNQITFIVDYNMMNVRSECFLQTIDKNRINNYEAEFAQYEKDLAAYKKEHG.................
U2P4Q4_9BACT/21-207                 .......CSSDNNLEEKDPNVEYV.NEAKNIL..NGDIVLSTKATMNGVDKTLLPNGCPTKFSFEWEKD-...--SMQLSLKGFTVGNMPLIVYFSCKCKFMQLNSWEKDEY.KG.EGWVKF.....KGKD.....GNVTGDP...KDNSGVQKGSGAG..VDGYLNVKTKEIIFIVNYNMMNVRSECFLQTIDRNRINNYAAEFAQYEKDLAAYKKEHG.................
A0A099BUL3_9BACT/24-207             .......CNSDDNLEQKAPALEYL.KEAKDIL..SGDIVLSTKATMNTVDKTLLPQGCPTKFNFSWEKD-...--SLRLRLDGFTVGKMPLIVYFSCKCKFMQLNSWEKDTY.KG.DGWIKF.....KGKD.....GSVTGNP...KDDSGVQQGSGAG..VEGYLNVKTHEIEFIVDYNMMNVRSECFLQTIDKNRINNYEAEFAQYEKELAAYKK---.................
G5GAY9_9BACT/18-205                 .......CSSDENLEKKDAAEALV.TETKNFL..NGDFVLNTRVLMNGVNKTLLPKGCPTKVNFSWNKPN...KNIFTIRLDEFTVGQMPLVITFACDAKIMQLTSWEKNEY.KG.DGWVKF.....QGVD.....GQLLIN-...-NETKNPVSKGSS..VKGFYNVKTHEINFIIDFNMMNVSSECFLQIVDKSRTNNYEAEFKKFEEELEAYKKEHG.................
I9VG70_BACFG/26-213                 .......CDSDEKITQEPPSQTYV.KKAKEIL..AGDIVLSTRATMNGVDKTLLKSGCPTKFNFSWRED-...-GMMILNLSDFSVGAMPFAISFKCATKIMQLNSWEQDEY.PG.DGWIKF.....VGTD.....GNVTTSG...DDAEDNQEGSGAR..VDGYLNVNTNQIEFIVDYNMMNVRTETFLQTIDKTRIDRFKEEFAQYEKDLEEAKKDQG.................
D3ID34_9BACT/11-197                 .......CNSDDNLEQKAPAQEYL.KEAKDIL..SGDIVLSTKATMNTVDKTLLPQGCPTKFNFNWEKD-...--SLRLTLDGFTVGKMPLIVYFSCKCKFMQLNSWEKDEY.KG.DGWIKF.....KGKD.....GSVTGNP...KDDSGVQQGSGAG..VEGYLNVKTNQITFIVDYNMMNVRSECFLQTIDKNRINNYEAEFAQYEKDLAAYKKEHG.................
E6MS85_9BACT/30-217                 .......CSSDHNLDERPVDESSI.ETAHQIL..DGDIVLSTKATLNGDDKTLLPEGCPTKFRFAWEDA-...-KTLRLQLLNFTVGNMPLKITFTSLCKFMQLNSWEKDEY.SG.DGWLKF.....KGVD.....GVVSADD...KGTGAVSKGSGAK..VDGYLNVKTHQINFIVNYNMMNVRSECFLQTIDKNRIKTYDEDFKKYEEDLKKYKEEHG.................
D8E004_9BACT/26-214                 .......CSSDEEIINSDANSELV.KEATNYL..NGEIVLSTNATMNGVNKTLLPEGCPTKFKFEWNKTD...AQTFTISLLDFTVGNMGMIINFKCDVKTMVLNSWEQKEY.TG.DGWIKF.....KGED.....GAVWGT-...DTDGSASSAKGSS..VQGYYNAKTHEIQFIVNYNMMNVRSECFKQTIDKSRLATFEADKKKYEVDLAAYKKEHG.................
D1VY46_9BACT/23-217                 .......CSGDERIEQSSVDAEYA.AKVKEIL..KDSIVLRSKAMMATVDKTLLPEGCPLKYYFHWNEGS...DKPLNIQLKNFSVGKMPVQIWFNIDCKLTRLNSWERDEY.KG.NGWVKF.....IGEY.....GATTYMPnknDTQHEYENGDGGSgyVQGYLNVNTKQIEFSTNFNVMLMQSYVYLQTIDYSKMDTFKEDFAKFEEDLEKYKQAHG.................
D1PW39_9BACT/23-223                 .......CNSDEKINSTPIQDEVIlAKAKELLtkEEFIVLRARAMMGPEDKTRLPEGCPLKYYFSWNTAAgkaDRPLNIKLIKFTVGSMPLTVDFNIHCKFIPLNKWERDEY.KG.DGWIKF.....VGEK.....GDVGYIPnekDEKGIYTDGEGGLgtVVGYLNVDTKEIEFSTNFNVMLMQSFVYRQKIDYSKKLTYEQDFKQYEEDLAKYKKEHG.................
A0A264Y3L7_9BACT/24-212             .......CSSDEEITDADANTELV.KEATNYL..NGEIVLRTNATMNGVNKTLLPEGCPTKFKFEWSKTD...AQTFTISLLDFTVGNMGMIINFKCDVKTMVLNSWEQKEY.TG.DGWIKF.....KGED.....GSVWGT-...DTDGSASSAKGSS..VQGYYNAKTHEIQFIVNYNMMNVRSECFKQTIDKSRLATFETDKAKYEADLAAYKKEHG.................
A0A4R7EMX5_9FLAO/20-209             ......c-STSESEPELEEEKENL.FE-QKFK..NKEVIIYTRAFRANGERTVGEMGMPVKFKFDYDKNE...PNKLYFEMPEFQFGKMPLAATISGNLDII--NKYV-DAY.PEkKDWIYFgtrssKATA.....GSYVYND...KGERIQHDSSPSA.eVNGYYNPNTNEIFMDINFKLMSVTSISPDQAFDIYPLEQYLELLDSY------------ydvhrqidk........
D7NCK4_9BACT/25-213                 .......CSSDEELKRADADIKLV.NEAKSFL..QGDIVLNTHATMGGVNKTLLPTGCPTKFNFTWSKTA...PQSFTISLLNFTVGKMGMIINFNCEVKTMQLNSWEKNEY.KG.EGWIKF.....YGEN.....GSVSGT-...DNEGVPSKAMGST..VKGYYNVMTHQINFIVNYNMMNVRSECFLQTIDKNRIKTYDEDFKKYEEDLKKYKEEHG.................
F8NAH8_9BACT/19-206                 .......CSSDEEITKTPVTDSYL.SQAKSIL..KDSIVFNAKAWQGTVNKTRLESGCPVKYHFSWKGD-...--TMTLQIKAFSVGSMPLRIWFVVNCKFMQLNSWEKDEY.TG.DGWIKF.....EGSG.....GNTTYLA...-LTTEYADGTGGSgtVTGYLNVLTKEIEFETNFNVMNFSTQVYQQKIDYSRMANFDAEFAQYEKDLAEYKKEHG.................
A0A133YWX3_9BACT/23-217             .......CSGDEKIEQTPVDTEYA.SKVKEIL..KDSIILRSKAMMATVDKTLLPEGCPLKYYFHWNEGS...DKPLNIQLKNFSVGKMPVQIWFNIDCKLTHLNSWEKDEY.KG.NGWVKF.....IGEY.....GSTTYMPnknDNNHEYENGDGGSgyVIGFLNVNTKQIEFSTNFNVMLMQSFVFLQTIDYSKMDTYEKDLAQFEADLAAYKKEHG.................
#=GC seq_cons                       .......CSSDEplpppssspEhl.pcAKphL..ss-IVLsT+AhMssV-KTLLPpGCPTKFpFpWpcs.....pshplpL.sFoVGpMPlhlhFsscsKhMpLNSWEKDEY.cG.DGWIKF.....hGcs.....GsVshss...cscuthppusGuu..VpGYhNVpTppIpFhlNaNhMNVpS-sFLQTIDcsRlssYEt-aspYEcDLttYKKEHG.................
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