#=GF ID   DUF531
#=GF AC   PF04407.19
#=GF DE   Protein of unknown function (DUF531)
#=GF AU   Waterfield DI;0000-0003-2885-5126
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   COG1772
#=GF GA   102.40 102.40;
#=GF TC   177.00 176.80;
#=GF NC   27.90 22.60;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 8 -Z 90746521 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0098
#=GF DR   INTERPRO; IPR007501;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Family of hypothetical archaeal proteins.
#=GF SQ   39
#=GS A0A4E0Q882_9EURY/2-168   AC A0A4E0Q882.1
#=GS F2KRN4_ARCVS/2-160       AC F2KRN4.1
#=GS Q8U3Y6_PYRFU/2-170       AC Q8U3Y6.1
#=GS Q8TZ83_METKA/8-178       AC Q8TZ83.1
#=GS D2RD77_ARCPA/2-162       AC D2RD77.1
#=GS A0A120MHW7_THEX5/12-181  AC A0A120MHW7.1
#=GS W0I9P4_9EURY/2-169       AC W0I9P4.1
#=GS M9SFE7_METAX/12-181      AC M9SFE7.1
#=GS A0A6B9T8I7_9ARCH/6-174   AC A0A6B9T8I7.1
#=GS A0A8J7XBK2_9EURY/1-157   AC A0A8J7XBK2.1
#=GS A0AA51UFF7_9EURY/2-168   AC A0AA51UFF7.1
#=GS H8IAZ2_METCZ/11-178      AC H8IAZ2.1
#=GS A0A0E3P2B0_9EURY/2-168   AC A0A0E3P2B0.1
#=GS F6BCG0_METIK/53-209      AC F6BCG0.1
#=GS A0A0Q4BDY8_9ARCH/7-176   AC A0A0Q4BDY8.1
#=GS A0A0E3SS61_METMT/2-168   AC A0A0E3SS61.1
#=GS D5E7U5_METMS/2-168       AC D5E7U5.1
#=GS A0A0A7LG44_9ARCH/5-175   AC A0A0A7LG44.1
#=GS C5A2V4_THEGJ/2-168       AC C5A2V4.1
#=GS D3RWY3_FERPA/2-160       AC D3RWY3.1
#=GS A0A401HPA9_9EURY/19-175  AC A0A401HPA9.1
#=GS F7XQQ3_METZD/2-168       AC F7XQQ3.1
#=GS D7DT04_METV3/29-199      AC D7DT04.1
#=GS L0L0B7_METHD/2-168       AC L0L0B7.1
#=GS N0BBA2_9EURY/2-160       AC N0BBA2.1
#=GS C6A3N9_THESM/13-181      AC C6A3N9.1
#=GS Q0W266_METAR/2-169       AC Q0W266.1
#=GS Y224_METJA/7-163         AC Q57677.1
#=GS A0A484F729_9EURY/2-168   AC A0A484F729.1
#=GS M4YMY4_THEXX/12-181      AC M4YMY4.1
#=GS Q8TU36_METAC/6-172       AC Q8TU36.1
#=GS A0AA43ZWM5_UNCTM/6-174   AC A0AA43ZWM5.1
#=GS A0A0Q4B210_9ARCH/6-175   AC A0A0Q4B210.1
#=GS A0AAF0MLT0_9ARCH/6-174   AC A0AAF0MLT0.1
#=GS Q5JDR7_THEKO/4-170       AC Q5JDR7.1
#=GS O29840_ARCFU/2-160       AC O29840.1
#=GS A0AAE4MJL1_9EURY/2-168   AC A0AAE4MJL1.1
#=GS R9T929_METII/10-179      AC R9T929.1
#=GS A0A0F7IFD9_9EURY/2-159   AC A0A0F7IFD9.1
A0A4E0Q882_9EURY/2-168              .LTLGIVNTYDKIKVLDAHYRAIARAAPICHAFGFSLALFDFPFK........MTPDELVEYVA.DKTTIGESGKFLRLLHEKKKLFVFDLPKKGFQPQLGSVVVTSSKPEERRSVMPEALASDILHNKSFLLLVGLGHKGLPKNLFEMAPYHLDIT.GNGTSLETCTAIGCIPAYL-m.
F2KRN4_ARCVS/2-160                  f-VLCLVNTYDKLKLHEIHLRSIARAAPLCYAFGLHLALLDFPFW........KERDEVVKAVR.DYTTIGEHGRYLEELDKSGKFHLIE----KIPAHFGVLVATTSKPDEGKRISTDDVPSL----TSATFLMGLGRKGLPKELMKKAKYHWDVT.GKGVSLETCAAMGVIAALV-g.
Q8U3Y6_PYRFU/2-170                  .LTIGLYNTYDTKKLHEAHIRAIARAAPVAYAYEFHLALIGFPFD.......sDDPKEVAERVA.STTTIGEGGKYLLELAKSNKFHLLDFPKRGFPPQFGEVIATTSKPSKEKVIGSREVAEMALRGKSLMLIIGLGRHGLPKEVFEISKYHLDITdGREISLETCTAIGIIPARI-k.
Q8TZ83_METKA/8-178                  .VTIGLYNSYDPRRFHEIHARTIARAAPLCVAFDFKLALFGFPLDdl....gvETPHELAEYVA.EETTIGASGREVLVLAERNLLEVYDYPVRGFPPQLGTIVGTTCRPDERKAIEPEDVVREILRPRSVTLVFGLGRRGLPAEVLEACEYHLDIT.GRRISLETATAIGAVTAVI-g.
D2RD77_ARCPA/2-162                  .IVLCLVNTYDKLKKHEIHLRSIARAIPLCYAFDFHLALYDFNFW........KNEREMVDEVV.SYTTIGEP-DYAYQMLDKNKIHLID----NFPAHFGELIATTPEPDRKKALSFEDMAR-VIRERSVTFLIGLGRRGLPKDLMERARYHFEAT.GRGVSLETCTAMGVIATTI-h.
A0A120MHW7_THEX5/12-181             .MTIGIYNAYDPKTFREPHRRVIARAGDLAMAFNMNLALFGFPIPe.....drRTPLEIANFIA.GTTSIGAHGDNFVQLAELGRFQTFPFPVKGFPPQLGKVVLTTCKPDTKKQLSTAQLAELVDNGQSILLIFGIGPHGTPKEVHGMSDIDFEVT.GGNFSLETCTALGAVCGAL-d.
W0I9P4_9EURY/2-169                  .LTLALYNSYDPKRLHEAHLRAIARAAPICYAFDFHLALVGFPFN........EKPLDLAERIS.ENTTIGEGGKYLLELAKKNKFHLLEFPKRGFPPQFGNIIATTRKPNEDKEITAIEVAKRALKGESFMLIVGLGRHGLPKEIFKLAEYHLDITdGRRISLETCTAIGAIPTKI-r.
M9SFE7_METAX/12-181                 .VTIGIYNAYDPKTFREPHRRIIARAGDLAMAFNMNLALFGFPIPe.....dkRTPKEIADFIA.GTTSIGAHGDNFVQLADLGRFQTFPFPGKGFPPQLGKVVLTTCKPDOKKMLNTSQLVEMIEGGQSVLLIFGIGPHGTPKEIHGISEYDYEVT.GGCYSLETCTALGSVCGKL-d.
A0A6B9T8I7_9ARCH/6-174              .ITIGLYNSYDQ-NFREPHRRVIARAGDLARAYDMSLALFGFPIPe.....daRTPKEIAEWVA.GTTSIGGHGKNFLEMAETGRFQCFPYPGKGFPPQLGEVILTTSKPDPKKQIPLSEAVSMVEHGQSITLLFGIGPHGVPKAVASIPKYNLDIT.PGCFSLETATALGAVCGA--fa
A0A8J7XBK2_9EURY/1-157              m-ILCLYNSYDKLRLHDIHIRSVARAAPVCCALGFHLALLDFPEP........-----MYDRVM.ASTTIGKSGYLLQQLKERSQFTELT---KTLP--LATLVITTSQPQPQKRVTCQQLVHMSSRGEVLAFIIGLGRRGLPRPLKKKALYHWDVT.DRGISLETCTAIGYIAARF-h.
A0AA51UFF7_9EURY/2-168              .LTLGIVNTYDKIKVLDAHYRAIARAAPICYAFGFSLALFDFPFK........MTADELVEYVA.DKTTIGESGKYLKMLHEKKHLFVFDLPKKGFQSQLGSVVVTTSKPEKKFSITPEAIADEIIHNKSFLILVGLGRKGLPKDLFGLAKHHLDIT.SQGISLETCTAIGCIPAHIM..
H8IAZ2_METCZ/11-178                 .LTLGLYNTYDKVKVVEAHYRGIARGAPIAYAYGFNLALIGFPYE........FEEKELVEFVK.DNTTIGASGLYLQKLYDEKRLFVMDVPEKGFPSQFGSLVVTTSHPERKKNASAEEIADMMIKNRPLLILIGLGRKGLPKEYFEMAQYHLDITdGKGISLETCTAIGAIAARL-y.
A0A0E3P2B0_9EURY/2-168              .LTLGIVNTYDKIKVLDAHYRAIARAAPICHAFGFHLALFDFPFK........MTAEELVAFVM.DKTTIGESGSYLKTLYETNHLSVFDLPKKGFQAQFGEIVITTSKPDPKKQIMPVQIAEEALRNRSFLFLVGLGRKGLPKELFGRGKYHLDIT.CKGLSLETCTAIGAIPANL-s.
F6BCG0_METIK/53-209                 .MTLILYNSYDKNRWHEAHKRAIARAAPICYAFDCNLAIMEFPCK........K-----EDILS.IETTIGNSGEYLHKLIEKNRFLIID----KYLPQLGIPIVATSKPDKKKAITPMDVVNL-LTKKPCGILVGLGRHGLPKDIVKMGEYHLDIT.GKGVSLETCTAIATIPAVI-s.
A0A0Q4BDY8_9ARCH/7-176              a-TIALYNSYDPTKFREAHRRALARAGPLALAFDLNLATFGFPFPa.....elQTPQEIADWVA.TTTSIGEHGGFLQELTEKGRFQTFPYPNRGFPPQLGEAILTTRKPADGRKIDIDEVVALLRSGRSVLVIFGLGPKGAPREVFEMCRRHMDIT.PGGFSLETCTAMGAVAGVI-a.
A0A0E3SS61_METMT/2-168              .LTLGIVNTYDKIKVLDAHYRAIARAAPICYAYGFTLCLFDFPFK........MTPEELVEYVM.DKTTIGESGKYLKLLHESNRLFVFDLPKKGFQSQFGTPVITSSKPEEKYAVTPEEIADGVERNKSYLLLVGLGRKGLPKKLFSFSDHHLDIT.CEGISLETCTAIGTIPSYI-m.
D5E7U5_METMS/2-168                  q-TIGIVNTYDRIKVLDAHYRAIARAAPICRIFGFSLALFDFPFD........MEKDELVKYVV.EKTTIGESGAYLQQLNEEHHFFVQDLPKKGFPAHFGKPVATTSRIDGSKRMTVMDAAEGIIHQDSYLFLVGLGRKGLPKSIIKQAPAHLDIS.SGGTSCETCTAMGAIPAYIM..
A0A0A7LG44_9ARCH/5-175              .ITIALYNSYDPNKFREPHRRVIARTGDLAMAFGMNLALLGFPIPe.....dvKTPVEIAEWVA.GTTSIGSHGDYFVELAEKGRFNKFPYPSKGFPPQLGEPILTTSKPDEKKRASVNDVAEMVKSGKSILLVFGIGPNGVPKDVAAIPKYHMDVTnGGGFSLETCTALGAVCGAL-s.
C5A2V4_THEGJ/2-168                  .LTLALYNTYDTRKLHEAHLRAIARAGPIAYAFGFHLALVGFPLR........GRPLDVAEEVS.SHTTIGEGGTYLLELARRNRFHLLDFPRKGFPPQFGTVVATTRKPSDEKEISPLELAERALRGESFIFLVGLGRHGLPGEIFKLARHHMDIT.GKRISLETCTAIGAIPAKI-r.
D3RWY3_FERPA/2-160                  .ITLCLVNTYDKLKLHEAHLRSIARIAPICYAFDFHLALYDFPFW........KREEEVVDAVC.DYTTIGEGGKYLRELHESGKFHLIE----SFESRFGEIVATTSKPDESKKISLDDIARF----RSAIFLFGLGRKGLPKDVLKKAKYHFEAT.GKNVSLETCTAIGVVATLI-w.
A0A401HPA9_9EURY/19-175             .MTLILYNSYDKRRWHEAHKRAIARAAPVCYAFNCNLAIMDFPCT........K-----EDIKS.IETTIGESGEYLKKLIESNRFNIVD----SYQPQFGIPIATTSKPNDKKSITPEEVAQL-LFKKPCGLYIGLGRRGLPREVFEFCKYHLDIT.KRRISLETCTAIGIIPAVI-d.
F7XQQ3_METZD/2-168                  .LTMGLVNTYDRIKILDAHYRAIARAAPICYAFGFNLALFDFPFT........MESDEMVDYVV.DKTTIGESGKYLRMLHESRRFYLSDLPKKGFQAHLGHPVVTTSKPEEKFRTTPQQLVDEIMRKRSFLILVGLGRKGLPKNMYQLSRYHLDIT.SCGVSLETCTAIGAIAANI-e.
D7DT04_METV3/29-199                 .CTMILYNSYDKSKWHEAHKRAIARAAPICTAFDWNLAIYDFPVDkienldglDTANNEKDVIKlIETTIGGSGSYLRNLIDNNRFLITN----KYQAQFGTPIATTSKPDPKKLITPKKVLEE-LQKKPCGVFIGLGRHGLPKDVMKMGHYDLDIT.EKGLSLETCTAIASIPAVI-s.
L0L0B7_METHD/2-168                  .LTMGIINTYDKIKVLDAHYRAIARAAPICHAFGFRLALYDFPFS........MTAEELVEYVT.DKTTIGESGKYLRLLHEKGHFFVFDLPKKGFQPQFGTAVVTTSKPEKKRAINPEEIASGILRKSSYLLLVGLGRKGLPKEMFEQAPLHLDIT.SAGISLETCTAIGCIPAYIM..
N0BBA2_9EURY/2-160                  .ISLCLVNTYDKLKLHEIHYRSIARAIPICYAYSFHLALLDFGFW........NDEKELVKEIV.EYTTIGDP-KYAESMLESGKIHLID----KIPAHFGSIVATTSRPEKGLSVEE--L-KKLLKSESLTFLIGLGRKGLPKDLLKKSKYHLDIT.WKGVSLETCSAIGVIASTI-y.
C6A3N9_THESM/13-181                 .LTLSLYNSYDPKKLHEAHLRAIARAAPICYAFDFHLALVGFPFE.......tKKPLEIGSEIS.KSTTIGESGKYLLELAKTNKFHLLDFPKLGFPPQFGQIVATTRKPDENKNISSLQLAERALRGESFMLVVGLGRHGLPKEIFKLAKYHLDITdGKRISLETCTAIGSIPTKI-r.
Q0W266_METAR/2-169                  .LTLGLYNTYDRNKVVEAHYRGIARGAPIAYAFGFNLALVGFPYD........FEKQELVDFVR.DNTTIGESGAYLQKLHDEKRLYVMDIPQKGFPAQFGSLVVTSSHGDKKKAVSSREVADMMARNKPLFILIGLGRKGLPKEYFEMAPYHLDITdGKGVSFETCTAIGAIAARL-y.
Y224_METJA/7-163                    .LTLILYNSYDKTRWHEAHKRAIARAAPICYAFDCNLAIMDFPCK........-----MEDILN.IKTTIGNSGEYLEKLIEKNRFFIVD----KFLPQFGIPIASTSKPDEKKAITPLDTA-YLLKKKPIGVYVGLGRHGLPKDIMESCVYHLDVT.EKRVSLETCTAIGSIPAVI-y.
A0A484F729_9EURY/2-168              .LTMGIVNMYDKIKIVDAHYRAIARAAPICYAYGFSLALFDFPFK........MDKDELVEFVM.DKTTIGESGKYLDLLNKEHHLFVSDLPPKGFPAHFGSVVTTTSKPYPQKVLTPLDVAAGNMRKKSYMFLVGLGRKGLPKDLFERAEYHLDIT.TKGISLETCTAIGAIPTQI-n.
M4YMY4_THEXX/12-181                 .MTVGIYNAYDPNTFREPHRRAIARAGDIAMAFNMNLALFGFPLPe.....dkKTPKEVADYIA.GTTSIGNHGDNFVQLAELGRFQTFPYPVKGFPPQLGKVILTTCKPEAKKQLTTAQLADMVDQGQSVLLLFGIGPHGIPDKVRPFSDYDFEVT.GGNYSLETCTALGAVCGAL-d.
Q8TU36_METAC/6-172                  .LTLGIVNTYDKIKVLDAHYRAIARAAPICHAFGFHLALYDFPFK........MTAEELVAFVM.EKTTIGESGSYLRVLYEKNHLSVADLPKKGFPSQFGDTVITTSKPDPKRKVLPVEIAEEALRNHSFLFLVGLGHKGLPKELFGRGKYHLDIT.SKGLSLETCTAIGAIPAHL-s.
A0AA43ZWM5_UNCTM/6-174              .ITIGLYNSYDQ-NFREPHRRVIARAGDLARAYDMGLALFGFPIPe.....daRTPKEIAEWVA.GTTSIGGHGRNFMEMAETGRFQCFPYPGKGFPPQLGEVILTTSKPDPKKQMSLDELVATVERGQSVTLLFGIGPHGVPKNVMSIPKHDLDIT.PGGFSLETCTALGAVCGAL-y.
A0A0Q4B210_9ARCH/6-175              .VTIGLYNSYDPTKFREPHRRILARAGGLALAFDMNLALFGFPFPd.....diKQPKELAQWVA.GTTSIGSDGGYFVELAEKGRFLSFSYPDKGFPPQLGEAILTTSKPDPKKAVTKEEVVAMINRGSSVLLVFGIGPHGIPRSPSSIPRYNLDIT.GGGFSLETCTALGAVVGAL-s.
A0AAF0MLT0_9ARCH/6-174              .ITIGLYNSYDQ-NFREPHRRIIARAGDLAMAFDMNLALFGFPIPe.....dtRTPVEVANWIA.GTTSIGHHGDYFVDLAEKGRFQKYPYPSKGFPPQLGEPVLTTCRAEESKKVTVGQLTDMVENGQSILLVFGIGPHGVPKDVMKIPRYNLDIT.TGGFSLETCAALGSVVGAL-y.
Q5JDR7_THEKO/4-170                  .LTLALYNTYDTKRLHEAHLRAIARAAPIAYAYGFHLALVGFPLD........GKPMEIAEEVS.RHTTIGDGGKYLQELAKANKFHLLEFPKKGFPPQFGTPVATTRKPWPEKEITPLDLTREALSGRSFLLLIGLGRHGLPEEIFKIARYHMDVT.GKRTSLETCTAMGAIGARI-a.
O29840_ARCFU/2-160                  .ISICLVNTYDKLKKHEIHLRSIARAAPLCYAFNFHLALLDFPFW........RSEKEVAEEVA.NYTTIGEGGKYLLYLAESGKLHLID----KIPAHFGEVVATTSKPDPDKVVNPDTLAAF----KSATFLIGLGRRGLPREMLKSAKYHLDVT.RKGVSLETCSAIGAIAML--la
A0AAE4MJL1_9EURY/2-168              .LTLGIVNMYDKIKIVDAHYRAIARAAPICYAYDFSLALFDFPFK........MEKEELVEFVR.GETTIGESGKYLELLNNEHHLYVSDLPPKGFPAHFGSIVTTTSKPSPQKTLTPLDVADGNLKKKSYMFLVGLGRKGLPKDLFERAEYHLDIT.SKRISLETCTAIGAIPTQI-n.
R9T929_METII/10-179                 .ITLALYNSYDPRSFREAHRRALARAGPLALAFDYNLAVFGFPFPq.....elQTPTEISEWVA.TTTSIGEHGGFLKELTAKGRFQTFPYPDKGFPPQLGEIVLTTRKPDEKKKITAEEVAEMVKRGQSVMLVFGLGPKGAPKEVFKMTKYHLDIT.PGGYSLETCTAMGATAGAM-a.
A0A0F7IFD9_9EURY/2-159              m-VACLVNTYDKLKLHEIHLRTIARAAPLCYAYDFHLALLDFNFW........ESREEMVEEVA.GYTTIGEGGRYLRMLDEMNRLHLID----RIPSHFGEIIATTSKPEK-KPLTMDELRRM----RSACFLIGLGRKGLPKDLIKKARHNLDIT.FKGVSLETCSAMGAIMSLV-w.
#=GC seq_cons                       .lTluLhNoYDphKh+EAHhRuIARAAPlCaAFsFpLALhsFPa.........tpscEls-hVs.spTTIG-uGcYLppLtEps+Fplh-hP.KGFPsQhGplVsTTSKP-ccKplosp-lAchhh+scShhlLlGLGR+GLPK-lhchucYHLDIT.ucGlSLETCTAIGuIsutl.t.
//