GenomeNet

Database: Pfam
Entry: DUF6097
LinkDB: DUF6097
Original site: DUF6097 
#=GF ID   DUF6097
#=GF AC   PF19592.2
#=GF DE   Family of unknown function (DUF6097)
#=GF AU   Williams LS;0000-0001-5551-8526
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Fragoso S;0000-0001-7018-3891
#=GF SE   Manual
#=GF GA   56.20 56.20;
#=GF TC   85.20 84.90;
#=GF NC   46.90 46.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   27694801
#=GF RT   Polyketide and nonribosomal peptide retro-biosynthesis and
#=GF RT   global gene cluster matching.
#=GF RA   Dejong CA, Chen GM, Li H, Johnston CW, Edwards MR, Rees PN,
#=GF RA   Skinnider MA, Webster AL, Magarvey NA;
#=GF RL   Nat Chem Biol. 2016;12:1007-1014.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a member of a biosynthetic gene cluster
#=GF CC   (BGC). This BGC (BGC0001796) is described by MIBiG as an example
#=GF CC   of the following biosynthetic class, NRP (non-ribosomal
#=GF CC   peptide). It  includes a member from the tauramamide
#=GF CC   biosynthetic gene cluster  from Brevibacillus laterosporus DSM
#=GF CC   25 and appears to be  predominantly found in bacteria [1]. 
#=GF SQ   20
#=GS A0A261UCC9_9BORD/37-195  AC A0A261UCC9.1
#=GS A0A241VWR8_9GAMM/1-151   AC A0A241VWR8.1
#=GS W0PHF8_ADVMD/1-159       AC W0PHF8.1
#=GS A0A2D1SSE3_9BACL/1-139   AC A0A2D1SSE3.1
#=GS A0A2V1K0R5_9BURK/1-153   AC A0A2V1K0R5.1
#=GS A0A1S8TKR8_9CLOT/1-139   AC A0A1S8TKR8.1
#=GS A0A1B2M1N9_9GAMM/1-152   AC A0A1B2M1N9.1
#=GS F4CB88_SPHS2/1-158       AC F4CB88.1
#=GS M1LWY1_9CLOT/1-139       AC M1LWY1.1
#=GS A0A084A1J3_9GAMM/1-152   AC A0A084A1J3.1
#=GS A0A212RLE3_9PROT/1-159   AC A0A212RLE3.1
#=GS A0A2S0U8E5_9BACL/2-157   AC A0A2S0U8E5.1
#=GS A0A3N1IVZ9_9ENTR/1-145   AC A0A3N1IVZ9.1
#=GS A0A4R6MXQ3_9BACL/1-139   AC A0A4R6MXQ3.1
#=GS S3N812_9GAMM/1-152       AC S3N812.1
#=GS E3E9M6_PAEPS/1-156       AC E3E9M6.1
#=GS A0A0G4JPJ4_9GAMM/1-109   AC A0A0G4JPJ4.1
#=GS A0A2U3MUX6_9GAMM/1-151   AC A0A2U3MUX6.1
#=GS J7U5R4_MORMO/1-152       AC J7U5R4.1
#=GS F0KGF1_ACICP/1-148       AC F0KGF1.1
A0A261UCC9_9BORD/37-195             ...v-.NFLYNLGASLQFLsfakQQLQGMHALIHAKQIPVEK.SQDFFQQATDLERALGDQSYAQSLRRYQNAKKCLVTVASLILAIAVILYALSLFGPTSGT--IKAAAGQLMSDFMLFaTTISIVAGV....LLVGLIGAHFYIRSLEKkl..igKNLSALWAKILQHWA-p...
A0A241VWR8_9GAMM/1-151              ....M.SNFQILSESLDNA....ELLKKLHHAIDEYRLPITS.KDDLNSQIVEIEKYLGGNEFSNLNAKTKFANLGTGLLGLPVLIYCLFLFGSRYANSFGFNIDAAAFNHSLFMLVINY.LWILIIYAL....LFIGLVAYFYKLNKQVK......AKIYSIVNKLF-----tiln
W0PHF8_ADVMD/1-159                  ....M.NLLHTFGASVQAMlfskQQLESMHRLIDSRNIPVEK.TEDFYQQAISLEQAAGYSDFTRRYQRFSTAQKIMNGIAYVVTGFALLVFLLSKF------GPLKEPIHALFSLLMSDfMLFAVLMSViagiILLILIGLYFYTRTLYNkl..lgSELVKLWKRTIEHWSP....
A0A2D1SSE3_9BACL/1-139              ....M.NVGRAVLRSLEFS....HELDLLHKHITHSQLPVRK.SDSFDNQCILLEQYLGEDTFQSTYKKMKRVNILSGLFALPVLLIVAAAFVYGRWIDRDYD---------IFGFFVEH.-PVLYIVPA....VLIVVTLVLAAFHSLLR......---RKLYGRIYPELK-y...
A0A2V1K0R5_9BURK/1-153              ....MlGNIKSLGTVLDNA....EVLKEVHRRIEQQRVPVAS.RDDIGPQLVELDRYMGTAAFTGLHARANKANLWSGVVALPILFYGLLLAFDSIVRKLGVGVDSAALLQAVNLWLINN.LLLVGAWAI....LVAGVIFYFKWLNGKVE......EAKLALVDAFFEKTEP....
A0A1S8TKR8_9CLOT/1-139              ....M.NFGRILHETLEFS....NELDILHKHITKNNLQVQK.SDSFDKQCFLLERSIGEERFKSTHKKMSIVNIMSGIIAFPVLLVILAAYIYAKWINKNFD---------VFRFILNN.-PEIYIIAA....VLLGITLILAMYHSILH......---KKLYYKIYPELK-r...
A0A1B2M1N9_9GAMM/1-152              ....M.SILSTLSKTVDNA....QKLKELHQYIEQRDLPIQS.RDEYPAQIIEIEAYLGTQQYRDFLKKKNTVNYLSGILALPALIFALFLFADRILSKWAIDLKVAEVSQKLLNFAIEN.SALMIIYAL....IFIATIIYFYALNRKTE......QYEEQVITAFLARTQ-r...
F4CB88_SPHS2/1-158                  ....M.GFLHSLGSSLQQVahlkEQLLYCHQWIDQHQIPVKKiEDNLDEQLVELEKWSHTNSYSAVLKKGKLWKSITVSIALLIGLVIGGIYLTNLL------FPEYFIQKQVFSWMFSHiLPVTIILAI....VLLFLLVSVQIGNSYMRstrgggKAYQQAWNEFRQHLKN....
M1LWY1_9CLOT/1-139                  ....M.GLGKILHEALEFS....NELDILHKHITKNNLQVQK.SDSFEKQCFLLERYMGEEHFQSIHKKMNIVNIMSGVFAFPVLLIILMVYVYAKWIDKKFD---------VFGFFLNN.-PALYIVPA....VLIAVTIIFAIYHSILR......---NNLYYKIYPKLK-e...
A0A084A1J3_9GAMM/1-152              ....M.GNINILMESTSNG....QLLKEIHYILEDNRLPIAS.KDELDSQVIELEKYLHGSEYSAINAKKNKVNIWTGVLALPILISSILLYLTKYTNFFGVDLLSAIEPSLTFSNFMTY.LPVIIIYAL....IFFGLILYFYFLNKKEK......NMMMAVIDQFVNKIN-k...
A0A212RLE3_9PROT/1-159              ....M.NFLYTFGSNVLFNnfamRQIEAFHAFIDSNKVPVNK.IDDLYKQTIALDRLAGTGGFERCFRRYSITRKILIILAIVIIIPALSIFLISKI------QSLEAITNSLKEFMISNfMEVAYTLGIggalLLAFLIGGYFYAQSQLDrl..vgPELGQVWHSIIEKWA-p...
A0A2S0U8E5_9BACL/2-157              ....M.NFFSLLSRSMQNNlfiqTQLNSAHTLIEEYQLPVQKlEDDFYAQFILLENYAGVNYFQRTLARYRRLNAWMLVLAVSILGAAAIIFGIEYT------MPEWKIADKLMDYLFEHfLPVIIGLTA....LFLLVIVLQFVRIHYANkl..msTAVNSSWRAILQKVE-s...
A0A3N1IVZ9_9ENTR/1-145              mgif-.----------SNT....RQLKKLHQHIEAKCIPVTS.KDELVPQVQELERYLGRTDFTALRGRKRIASILTAIVSLPVLGYGAIIGLDRYFAFEAGGFNARQVTLDIAQWLAGN.MQGLAVYGV....LFLVITFYYRWIDFCMG......RKVKNVIKQFMTQT--gg..
A0A4R6MXQ3_9BACL/1-139              ....M.NYGRALHNVLEFS....HQLDVLHKHMTESNLPVRK.SDSFDRQCFLLEQHLGEDVYQTTYKKMKKVNLLSGITALPVLLVIAVAYIYSRWIDKELD---------MFGFFIDH.-PVLYLVPA....VLIVVTLVLAVYHSILR......---KKLYYQIYPELK-s...
S3N812_9GAMM/1-152                  ....M.NNLSLLSDALDDA....QYLKELHYFIEEHKLPITS.KDDLDEQIIVIEKYLGQDQFTQLHAKRKKANLGTGILALPVLFYCIFLFMSRYLGYFDVDLNVKSISQVIFADAIQY.IWFVALYAL....AFIGLVAYFYKLNTQAK......HTIRQVTQQLVQRTQP....
E3E9M6_PAEPS/1-156                  ....M.NVLGQLGSAIQSSlfiqSELKKAHALIQKHDLPVEQvEDDFHKQIILLEQYAGTRIFQQGLARYKVINAMLLIISVIILLAAVIVATVEYL------QPERHLLQVLVNAMFDYwVPSITILSV....AFVGVIVLAIVRNVYARrl..htRVLDRSWQAIFQHVD-k...
A0A0G4JPJ4_9GAMM/1-109              ...m-.-------------....-------------------.----------IERYLGGSKYANLNKKKRSANIIAGILALPLLIFSLFLFFSRYQKYFSFGFDMENTMETLFLMIIEY.PWAVILYAV....AFAAMVFYFYRLNSQSM......AEADKIIHAFMTQ---sp..
A0A2U3MUX6_9GAMM/1-151              ....M.NNFQILSESLDNA....ELLKKLHHAIDEHHLPINS.KDDLNDQIIEIEKYLKENEFCNLLEKRKFVNLGTGVLALPVLIYCIFLFGSRYASNFGFNIDAAAVNHTLFIGIINY.LWIVIIYAL....LFVGLVVYFYKLNKQAN......EKIYSITNKLFDRL--n...
J7U5R4_MORMO/1-152                  ....M.GIITAFAKSIDNS....QLLRLLHQQIEKQDAPVAC.RDDLDDQLTDIAAYMHDEHYPALAKRRKKVNMLTGLLALPVLLFSLLLFSQKIIDALSLNIDISYLSLTLLDYSLTY.IWAVFIYAA....VLFGTIFYFYFLQKQTE......KYAGHLIDDFINRIS-h...
F0KGF1_ACICP/1-148                  ....M.GNLTILGEALESA....EILKNIQYHIKDNRLPISL.KDDLNKQVIEVEKYFGEDDFERLEVKKNKINIWTGVLAVPILIYCIALFLSRYVHNFGINIDVDVINHMLFDNIFKY.IWIVIIYAV....IFFGLIGYFYILNNHSK......KLIEKNVNKL------ls..
#=GC seq_cons                       ....M.shhphLupulpsu....ppLctlHphI-cppLPVpp.cD-hspQhltLE+YhGpspFpshhpKhppsNlhoGllALPlLlhslhlah.phh..hshshs.tth.ptlFshhlsa.h.llhlhul....lhlullhhaahhpshhc......phhpplhpplhp+hp.t...
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