GenomeNet

Database: Pfam
Entry: DUF6234
LinkDB: DUF6234
Original site: DUF6234 
#=GF ID   DUF6234
#=GF AC   PF19747.1
#=GF DE   Family of unknown function (DUF6234)
#=GF AU   Williams LS;0000-0001-5551-8526
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Fragoso S;0000-0001-7018-3891
#=GF SE   Manual
#=GF GA   27.50 27.50;
#=GF TC   28.20 27.90;
#=GF NC   27.30 26.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   19362651
#=GF RT   Enzymology of aminoglycoside biosynthesis-deduction from gene
#=GF RT   clusters.
#=GF RA   Wehmeier UF, Piepersberg W;
#=GF RL   Methods Enzymol. 2009;459:459-491.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a member of a biosynthetic gene cluster
#=GF CC   (BGC). This BGC (BGC0000709) is described by MIBiG as an example
#=GF CC   of the following biosynthetic class, saccharide. It includes a
#=GF CC   member from the neomycin biosynthetic gene cluster from
#=GF CC   Streptomyces fradiae  ATCC 10745 = DSM 40063 [1]. This family
#=GF CC   appears to be predominantly found in Actinobacteria.
#=GF SQ   111
#=GS A0A561EML4_9ACTN/14-135   AC A0A561EML4.1
#=GS A0A101NXP2_9ACTN/21-141   AC A0A101NXP2.1
#=GS A0A1C4M2F5_9ACTN/33-163   AC A0A1C4M2F5.1
#=GS A0A6B3H1R5_9ACTN/24-135   AC A0A6B3H1R5.1
#=GS K4R831_STRDJ/11-138       AC K4R831.1
#=GS A0A5C8NPU7_9ACTN/10-128   AC A0A5C8NPU7.1
#=GS A0A3L8JB20_9ACTN/1-104    AC A0A3L8JB20.1
#=GS A0A5Q4TG23_9ACTN/14-140   AC A0A5Q4TG23.1
#=GS A0A6G2UHB9_9ACTN/24-158   AC A0A6G2UHB9.1
#=GS A0A371Q1I5_9ACTN/22-120   AC A0A371Q1I5.1
#=GS A0A5S4H169_9ACTN/10-126   AC A0A5S4H169.1
#=GS A0A2U2ZKE8_9ACTN/26-144   AC A0A2U2ZKE8.1
#=GS A0A2A2YTX1_9ACTN/1-92     AC A0A2A2YTX1.1
#=GS D6KD32_9ACTN/29-144       AC D6KD32.1
#=GS A0A0M9YDV5_9ACTN/13-138   AC A0A0M9YDV5.1
#=GS A0A4P6TUX8_STRSO/1-110    AC A0A4P6TUX8.1
#=GS A0A1R1SMY6_9ACTN/1-108    AC A0A1R1SMY6.1
#=GS H2K9N3_STRHJ/21-140       AC H2K9N3.1
#=GS A0A2P6UID8_9ACTN/9-106    AC A0A2P6UID8.1
#=GS A0A0N0AFL2_9ACTN/16-131   AC A0A0N0AFL2.1
#=GS A0A1N7EMC5_9ACTN/3-119    AC A0A1N7EMC5.1
#=GS A0A0N0XXA6_9ACTN/17-132   AC A0A0N0XXA6.1
#=GS A0A2W2DMP7_9ACTN/7-138    AC A0A2W2DMP7.1
#=GS A0A1C5HD87_9ACTN/5-135    AC A0A1C5HD87.1
#=GS A0A1D8G9T8_9ACTN/22-149   AC A0A1D8G9T8.1
#=GS A0A5N8V927_9ACTN/6-122    AC A0A5N8V927.1
#=GS A0A6B2V7K7_9ACTN/21-138   AC A0A6B2V7K7.1
#=GS A0A2M8M0G6_9ACTN/25-144   AC A0A2M8M0G6.1
#=GS A0A4R4TKA0_9ACTN/20-78    AC A0A4R4TKA0.1
#=GS A0A059VYP6_STRA9/17-132   AC A0A059VYP6.1
#=GS A0A6B3HZP6_9ACTN/20-152   AC A0A6B3HZP6.1
#=GS F2RJZ1_STRVP/42-171       AC F2RJZ1.1
#=GS A0A2M9IWE4_9ACTN/19-141   AC A0A2M9IWE4.1
#=GS D6K1Q8_9ACTN/21-138       AC D6K1Q8.1
#=GS A0A1J4NBL7_9ACTN/1-115    AC A0A1J4NBL7.1
#=GS A0A516R3N1_STRST/17-142   AC A0A516R3N1.1
#=GS Q82PL0_STRAW/1-109        AC Q82PL0.1
#=GS A0A6G2BCV3_9ACTN/21-156   AC A0A6G2BCV3.1
#=GS A0A1Z2LC57_9ACTN/29-144   AC A0A1Z2LC57.1
#=GS A0A0A1DPB4_NOCSI/1-116    AC A0A0A1DPB4.1
#=GS A0A1H8LHR0_9ACTN/1-100    AC A0A1H8LHR0.1
#=GS A0A1X4GRK8_9ACTN/21-139   AC A0A1X4GRK8.1
#=GS A0A429QMA4_9ACTN/1-93     AC A0A429QMA4.1
#=GS A0A1Z1W665_9ACTN/20-149   AC A0A1Z1W665.1
#=GS S2XX58_9ACTN/1-88         AC S2XX58.1
#=GS A0A4V5MJ79_9ACTN/8-119    AC A0A4V5MJ79.1
#=GS A0A1G9MXX7_9ACTN/9-142    AC A0A1G9MXX7.1
#=GS V6JK57_STRRC/21-127       AC V6JK57.1
#=GS A0A4P7SP87_9CELL/26-149   AC A0A4P7SP87.1
#=GS A0A367HRE1_9ACTN/1-108    AC A0A367HRE1.1
#=GS A0A0F2TD49_STRR3/1-112    AC A0A0F2TD49.1
#=GS A0A250VW31_STROL/17-132   AC A0A250VW31.1
#=GS A0A6B3I0Z1_9ACTN/24-147   AC A0A6B3I0Z1.1
#=GS A0A2K8PFS6_STRLA/16-144   AC A0A2K8PFS6.1
#=GS A0A561EQ98_9ACTN/26-145   AC A0A561EQ98.1
#=GS A0A2M9J4N2_9ACTN/1-109    AC A0A2M9J4N2.1
#=GS A0A1K2FPL4_9ACTN/17-131   AC A0A1K2FPL4.1
#=GS Q7AKK7_STRCO/33-155       AC Q7AKK7.1
#=GS A0A420UV43_9ACTN/6-103    AC A0A420UV43.1
#=GS A0A1E5P070_9ACTN/8-105    AC A0A1E5P070.1
#=GS A0A4R7MLU2_9ACTN/20-133   AC A0A4R7MLU2.1
#=GS A0A1Q5JZE8_9ACTN/17-132   AC A0A1Q5JZE8.1
#=GS A0A2D3U3G8_STRC0/161-290  AC A0A2D3U3G8.1
#=GS A0A2N0JIT5_9ACTN/23-139   AC A0A2N0JIT5.1
#=GS A0A2N0JV07_9ACTN/5-124    AC A0A2N0JV07.1
#=GS V4IXK0_9ACTN/3-124        AC V4IXK0.1
#=GS A0A498AWI6_9ACTN/1-109    AC A0A498AWI6.1
#=GS A0A2M9IL57_9ACTN/1-109    AC A0A2M9IL57.1
#=GS A0A2S4Y648_9ACTN/1-111    AC A0A2S4Y648.1
#=GS A0A176KT76_9ACTN/21-137   AC A0A176KT76.1
#=GS A0A1D7VL53_9ACTN/17-132   AC A0A1D7VL53.1
#=GS A0A2M9CNH0_9MICO/152-276  AC A0A2M9CNH0.1
#=GS A0A4V3EZB7_9ACTN/34-157   AC A0A4V3EZB7.1
#=GS A0A0X3XMH2_9ACTN/21-138   AC A0A0X3XMH2.1
#=GS S4A7M1_9ACTN/20-147       AC S4A7M1.1
#=GS A0A1Q9TQE9_9ACTN/6-104    AC A0A1Q9TQE9.1
#=GS A0A1C5BE11_9ACTN/39-168   AC A0A1C5BE11.1
#=GS A0A223S7V8_9ACTN/1-121    AC A0A223S7V8.1
#=GS A0A2G7F010_9ACTN/17-132   AC A0A2G7F010.1
#=GS F4H5W1_CELFA/166-290      AC F4H5W1.1
#=GS A0A1V9K2F9_9ACTN/17-136   AC A0A1V9K2F9.1
#=GS A0A1H7YDE0_STRJI/19-143   AC A0A1H7YDE0.1
#=GS A0A1C5C2Y3_9ACTN/38-162   AC A0A1C5C2Y3.1
#=GS A0A2X0IUP6_9ACTN/1-120    AC A0A2X0IUP6.1
#=GS A0A4R7H2R3_9ACTN/21-136   AC A0A4R7H2R3.1
#=GS A0A1C5G8A4_9ACTN/8-137    AC A0A1C5G8A4.1
#=GS A0A1Q5L3S2_9ACTN/7-116    AC A0A1Q5L3S2.1
#=GS A0A1C5K448_9ACTN/1-120    AC A0A1C5K448.1
#=GS A0A0G3UZ55_9ACTN/21-144   AC A0A0G3UZ55.1
#=GS A0A1H7TQM6_STRJI/19-142   AC A0A1H7TQM6.1
#=GS E4N0S3_KITSK/20-141       AC E4N0S3.1
#=GS A0A101J5V5_9ACTN/29-141   AC A0A101J5V5.1
#=GS D5UHU4_CELFN/24-147       AC D5UHU4.1
#=GS A0A1C4ZUE5_MICEC/7-137    AC A0A1C4ZUE5.1
#=GS A0A0C2AHI4_9ACTN/21-146   AC A0A0C2AHI4.1
#=GS V6KMD2_STRNV/1-61         AC V6KMD2.1
#=GS A0A327WD05_9ACTN/8-106    AC A0A327WD05.1
#=GS S5UUP6_STRC3/21-79        AC S5UUP6.1
#=GS A0A197SVB0_9ACTN/21-136   AC A0A197SVB0.1
#=GS A0A1Q4WH14_9ACTN/1-110    AC A0A1Q4WH14.1
#=GS A0A2S0WM33_9ACTN/14-134   AC A0A2S0WM33.1
#=GS A0A1K2FW02_9ACTN/21-137   AC A0A1K2FW02.1
#=GS A0A1B6AJB3_9ACTN/18-113   AC A0A1B6AJB3.1
#=GS A0A0Q5C8Z9_9MICO/13-135   AC A0A0Q5C8Z9.1
#=GS A0A561UAG8_9ACTN/23-137   AC A0A561UAG8.1
#=GS A0A4R3D6I8_9ACTN/18-115   AC A0A4R3D6I8.1
#=GS A0A0Q8Q263_9ACTN/8-130    AC A0A0Q8Q263.1
#=GS A0A2N5WUE7_9ACTN/9-100    AC A0A2N5WUE7.1
#=GS A0A2I0SY91_9ACTN/21-137   AC A0A2I0SY91.1
#=GS A0A0M9ZNA7_9ACTN/21-143   AC A0A0M9ZNA7.1
#=GS A0A0F0HYB5_9PSEU/1-122    AC A0A0F0HYB5.1
A0A561EML4_9ACTN/14-135              ................ra--PWFLDLLGACAVLALETA.F...L.A.....AV-G......FSALMAGWASH......DESSAST......PSM.GSHALA.LG.VLAVV.A.G..I...AAVG..L.FRARAPITA..ASQV.LAA.A.V..L.AFSAL......AIGFGAY.V..-.-..---..-......---.----.....---..-..--------radshrpsggvtwqmntsskrg
A0A101NXP2_9ACTN/21-141              ..................RADTGADIGAGCGLAFLELA.V...L.V.....VDFGl....wFLSGVSLDTA-......-EPAQTD......-SL.WGYLTA.AA.GVAAF.A.F..A...AALV..A.ARARAVVTV..VSQV.VTA.V.L..V.TLVISa...gaLAQAHED.-..-.-..---..-......---.----.....---..-..--------gsagrdghschavparprc...
A0A1C4M2F5_9ACTN/33-163              .............avngc-----LDVVLGLLLVFLEAL.I...C.G.....VAAL......QLALSRADPGG......PAPTGPP......TTD.WTPVLV.FG.GITAA.A.C..L...FAVV..L.IRADWPWAG..AIQV.LAA.L.V..L.CVVTL......RAGHEDY.G..R.P..QPV..P......APA.PSYDpgrtgHQC..L..SGGDSREC......................
A0A6B3H1R5_9ACTN/24-135              ............gplaqf--------GVALGLVVLETA.S...A.A.....AVLLf....wFGAALHLDTG-......--TPAPE......VSP.TPYLLA.LA.AIGLC.A.G..A...AAFA..S.GRRREWGVA..VTQG.LMA.AsL..I.GAALVg....aTLETRGA.A..R.D..QPP..P......AAP.----.....---..-..--------gv....................
K4R831_STRDJ/11-138                  ..................RPHPAADVFLALALLVADGV.A...A.L.....VACL......----FGLDAAGyt..llGPDAGTS......-VS.FTPFAIgLG.VVGGL.V.V..G...TAWL..A.HRNRAPVTA..ALQL.LAG.L.V..L.LLIAG......LGQLQQY.D..E.D..HPP.aP......EPG.YSGP....qSQC..L..SGGDNSEC......................
A0A5C8NPU7_9ACTN/10-128              ...............arg---------AGIGLLVLEPL.V...I.L.....LLWW.....qFLDVYLSFFGD......TREAEPG......-DG.RRYLVT.AS.ICLAC.P.L..VagaAAVL..V.RSRRLFWWS..VAG-.LVL.A.V..V.AGVLF......AVPDDRF.T..R.D..EPT..Y......-PI.DPGY.....TPC..Y..SGS--NDC......................
A0A3L8JB20_9ACTN/1-104               .................m----------------LELL.A...L.G.....VIVAl....wWMSGWTFDPA-......-GSYAPD......-PV.WGYLVA.IG.VLGLL.A.L..G...AAWR..A.SSRGAGATA..WVQG.LVF.A.V..S.LLLIAa....gAVIQH--.R..Q.D..NPP..P......-P-.----.....SPC..R..DSPSAAWC......................
A0A5Q4TG23_9ACTN/14-140              ................pv--HLFADCLLALVLFALEAA.V...L.L.....LFA-......VASAFSLTQRT......PGEIRQG......ETR.MTLVLW.AA.AA--V.L.A..V...IGYV..L.NRSGFVISG..MLHA.LSA.V.A..C.VVFAF......AVMTGGD.E..G.A..GPP..P......SSP.VSDHrg.pgGQC..R..SGGDSDEC......................
A0A6G2UHB9_9ACTN/24-158              .............apggc-----ADPLVGVLLVVAEAA.AgalL.A.....IWLM......VRGLARSHEATggklsaPPPADPG......-TD.WTPVVV.IA.VLALL.V.A..C...VAAE..L.LRSGWYWSG..GTQV.VVA.V.A..L.GVTVL......ATAVQGS.G..R.E..APE..P......APA.PTYV....sPPC..R..SGGDSDEC......................
A0A371Q1I5_9ACTN/22-120              ...............rap----AADFGPAVGLLVLDVI.V...V.L.....VTLL.....pVMNEAGYHFF-......DTAANSD......FDS.TSTVLT.LI.ILGAV.A.G..L...SAWP..L.LRGRFFISG..WLQI.LVA.G.G..L.WGWT-......-------.-..-.-..---..-......---.----.....---..-..--------lygaaqgg..............
A0A5S4H169_9ACTN/10-126              ..............gmtl-------------------G.I...L.A.....IIWF......FGVPLCLWQSLva..glGSPAGNR......AEM.DAWVTA.AA.VIFTV.VpI..L...AAGI..C.AFTGRVVRA..WIFG.LVA.T.V..C.VGLVLa...glYRAERQA.E..S.R..RPP..P......-PL.PSGY.....CAE..F..SGG-DSDC......................
A0A2U2ZKE8_9ACTN/26-144              ..........rgdgfagg--------CISLIVLLIEVP.-...V.A.....FLLG......LTSVIRGWGRV......DEQTAAP......PMD.WVPVLW.LG.GFTLG.V.L..V...IAML..F.LYSAHPFAG..AVQL.LVA.A.I..A.LCFTI......AVWQHQY.E..R.A..HPR..P......LPT.RAGI.....S--..-..--------psghv.................
A0A2A2YTX1_9ACTN/1-92                .................m---RGRNIIAVLGLLPVNIL.A...V.G.....YGW-......LAAGMTGWAAS......YDDEPYE......---.-PPLAE.LG.TTCGV.V.A..A...VGVV..L.WLVRLRGAA..VFQV.VPL.L.I..L.AMLML......-------.-..-.-..---..-......---.----.....---..-..--------psephp................
D6KD32_9ACTN/29-144                  ..................RTRPAADLALAIPLFLLEIA.W...L.A.....VDWI......YGYGLDVWAAE......GDRAEID......AAA.LAHMGR.VR.TLLVV.V.L..V...LAVL..A.AVSRARYTV..IAHL.LVA.M.V..A.GGVLA......-ISHDEW.D..S.R..HRP..P......---.----.....SGC..V..RYS--ANC......................
A0A0M9YDV5_9ACTN/13-138              ..............dvgr----PGSGCAAFGLVLLELL.A...L.C.....GVALv....wLGESFRLDTS-......--RDEPD......VRL.DGYLGA.LA.VVFLV.A.L..V...VALV..A.GWRGARAVV..WSQL.VMM.T.L..L.LAVIVa...ggAAQRHED.E..R.D..HPA..P......GFT.GM--.....VGC..R..SGGDDSEC......................
A0A4P6TUX8_STRSO/1-110               .................m------DLALAIPLFLLEIV.W...V.V.....LDAV......YGRGLEVWAAQ......GEQARID......AAD.LAFMDR.LQ.VLQIV.V.V..V...LAVL..A.AVFRARWTA..IAHL.LVA.L.L..L.GGALA......-GEHRDG.E..K.S..HSA..P......---.----.....-GC..V..RYS--ANC......................
A0A1R1SMY6_9ACTN/1-108               .................m-------------LIVVQLA.V...V.A.....VLF-......----VGAWAEEy...fsWDPQSIP......GPV.GPYIVK.MG.VVAGI.A.A..V...AGIV..A.GARGSGAVA..YGQA.LVV.V.V..T.LVAMAvtdamgDSAHEEY.R..R.Q..KCY..D......APA.----.....---..-..--------dpgcad................
H2K9N3_STRHJ/21-140                  ..................RADRGADVGAGCGLVVLELV.A...L.V.....VIFGl....wVLSGWTFDTA-......-ETVTAD......-PL.WNYLAA.AG.AVGVL.A.L..A...AGLI..A.AWAGAVVTV..ATQA.VVA.A.L..V.CLVVFg...gaAAQSHQD.Q..V.C..RDM..P......SA-.----.....SGC..R..GAG-----rp....................
A0A2P6UID8_9ACTN/9-106               .............altwl-----TDVLFAVTFLACEAA.V...L.F.....VLW-......LRAAMVAWAAS......YNGVVEQ......-DW.DGTLVA.LG.VVAAC.A.V..L...LAVV..L.WRRRWPVAA..VTQG.LAA.A.V..V.ALLMA......-------.-..-.-..---..-......---.----.....---..-..--------gvlafeg...............
A0A0N0AFL2_9ACTN/16-131              ..................RTRLGVDLAFAIPLFLLEAG.W...L.A.....LDAV......YGYGLDVWAAQ......GEQWEID......AAS.LAYMGR.LR.TLLIT.V.L..I...LAVL..A.AVSRARWTV..IAHL.LVA.L.L..A.GGALM......-ATQHDW.D..R.S..HAP..P......---.----.....PGC..V..RYS--ANC......................
A0A1N7EMC5_9ACTN/3-119               ..............wlig-------------------A.L...V.L.....LGWI......FSIGLEGWADQhsdqgaGADALAR......KAN.VALLLL.AA.EVVAG.P.A..V...IAVV..A.RSGLLRRTA..AVYL.VIA.L.G..L.GVLAV......PVAVGAY.R..D.F..APA..P......PPP.PP-P.....TIC..QehSGG-DT--rc....................
A0A0N0XXA6_9ACTN/17-132              ..................RTRWGVDLAFAIPLFLLETA.W...L.V.....LDWM......LGFGLEVWAAQ......GDQDQID......AAG.VAHIGR.VW.VVLIA.V.L..I...MAVL..A.GVFRARWTV..ITHL.LVA.L.L..A.GGVLV......-LAQHQQ.D..S.S..HAP..P......---.----.....PGC..I..RYS--ANC......................
A0A2W2DMP7_9ACTN/7-138               ssrwapttvalltlawal------------------AM.S...L.L.....LWWW......FGIGLEGWADAhs.nqgVRSAELR.....qKGA.SATLLV.AV.VAVGG.L.I..L...IAIA..A.FTGRLVRTG..ALYL.ALA.I.V..L.GALVA......PFAAGAY.R..T.L..TPP..P......PPP.PA-P.....TVC..QehSGG-DN--rc....................
A0A1C5HD87_9ACTN/5-135               atsrwapttvalltlawv------------------VA.V...LaT.....LWWW......FGIGLAGWADQhs.gqgTRSAERE......-AA.RATLLL.AL.VAVGG.P.I..V...VAVA..A.FTGRLVRTG..AVCL.AVA.I.V..L.GALVA......PVAADAY.R..M.Q..NPP..P......PPP.PAPT....vCQE..R..SGG-DTRC......................
A0A1D8G9T8_9ACTN/22-149              ..................RARRGPDAAAGCVLVLLELT.A...L.A.....VILLa...wpFLDHFELDPQ-......-APREPF......-TL.WRYLPA.VA.VLGGL.V.L..V...AAVL..A.ARARAVVTA..VSQT.AMG.V.L..I.AAVLLg...gtALQRHED.E..R.G..RPV..P......APT.-GGF.....SGC..R..SGGDSDEC......................
A0A5N8V927_9ACTN/6-122               .................e--RRGRLVAIAVALAVVEVA.A...L.A.....LIWL......------SWAATy...wsFDPQSHG......VPP.GPYLHE.AA.FVAVA.A.L..V...ASVV..G.AVRRAHVIT..ITQI.VMV.V.V..V.CGILS......-SAKVAG.E..R.A..YET..S......YR-.----.....DAC..R..SG------lgcattp...............
A0A6B2V7K7_9ACTN/21-138              ..................RADLGADIGIGCALVFLEIL.A...L.A.....VVFGl....wFLSGFNLDPA-......-TTVRAD......-SL.WGYLAA.VG.GVGAL.A.V..V...ATAI..A.ARARAYVTV..ASQS.VVA.A.V..V.SLALFg...gyVAQSHED.A..H.C..ETA..P......NA-.----.....--C..H..E-------gpsk..................
A0A2M8M0G6_9ACTN/25-144              ..................RTRRIADASAASALVALELL.A...L.D.....AV--......----LDLWFPAr...ltLGPVAPPp....pHPL.WGYLAI.TG.ALCAL.L.V..W...TARA..A.RRRGARVTA..WTQG.LMA.V.A..T.AVLLMc...gtSESFHGY.A..T.-..--M..P......PP-.----.....DGC..G..TSPSVPRC......................
A0A4R4TKA0_9ACTN/20-78               ................vv--DRVADISGALGLLVLELM.A...M.F.....AVFVw....wVLSGWSLDPQ-......-TPADPD......-PV.WGYLAA.YA.AL---.-.-..-...----..-.---------..----.---.-.-..-.-----......-------.-..-.-..---..-......---.----.....---..-..--------ar....................
A0A059VYP6_STRA9/17-132              ..................RTRLGVDLALAIPLFLLETA.W...L.V.....VDWI......FRYGLELWAAQ......GEQARID......VAS.LAHTGR.VR.VLLIS.V.L..I...VAVL..A.AVFRARWTV..IAHL.LVA.L.L..A.YGSLT......-AAQYDW.E..R.R..HAP..P......---.----.....PGC..V..RYS--ANC......................
A0A6B3HZP6_9ACTN/20-152              ..............rpgg----CADPAVGLLLTISEAI.V...L.A.....VLLIw....lGLRGLGRSHAP......VDSGAPPasgagaETD.WVPTIA.FG.VLALV.V.V..V...LATV..L.LRDRWYWAG..GIQV.LVA.V.A..L.CTLTL......TSAFQAD.A..D.A..PPA..P......APA.WN-S.....PPC..R..SGGDSEEC......................
F2RJZ1_STRVP/42-171                  ..................RQRTVHDVLLALALLLLDVG.F...V.L.....FAV-......FTLLFRPWGSR......YDPERPGp....pPMD.WVPVLT.FG.AITAG.I.L..L...LAFA..L.WRGGWSWAP..GGQF.AAA.L.L..L.AFLTV......HGATQEW.A..R.S..HPA..P......PPA.QAPVe..grCVC..T..SGGGPCEC......................
A0A2M9IWE4_9ACTN/19-141              ..................RTSLGTDLAGGILLLMIEAA.-...L.G.....AWKL......FSDSMELWAAQ......GDRTRTD......ASG.LSGIAW.LE.HFLVV.V.L..I...LAVV..A.ALSRAPWTT..VLQL.LVA.G.A..T.AVLLA......-LAQHGY.D..Q.R..HPE..P......SPP.PDPH....yTPC..Y..SGS--GRC......................
D6K1Q8_9ACTN/21-138                  ..................RADLGADIGIGCALAFLEIA.A...L.A.....VVVGl....wFLSGFNLDPA-......-KTVRPD......-SL.WGYLAV.VG.GIGAF.A.V..V...ATAI..A.ARARAFVTV..VSQT.VVA.L.L..V.SLVLFg...ghTAQSQED.A..H.C..DTA..A......---.----.....SAC..-..--------hdgpsr................
A0A1J4NBL7_9ACTN/1-115               mavvaignlmsnwldvyl--------------------.-...-.-.....----......------VFFGE......QPQVMPS.....nVAS.YRVWAT.IM.VLALV.A.G..V...LAHL..LnRRRRLPGTV..WQAL.LLV.G.G..A.AILVL......CYIPGAV.D..L.P..EPE..P......ERE.QGGYg...aPPC..Y..SGGDNDEC......................
A0A516R3N1_STRST/17-142              ..................RADTGPDVGAAVGLLVAEVL.V...L.A.....GILAv....wVASGLTFDPA-......-ADAEFD......-RL.DGCLVA.AA.CVGGL.A.L..L...ATAV..A.IRVRAPVTA..WSQG.FMV.V.V..I.AVAVLa...gfSYQRHED.E..V.R..EPA..P......--A.WTGQ.....VGC..R..SGGGSDEC......................
Q82PL0_STRAW/1-109                   .................m------------ALVVVEMA.I...L.A.....LIGL......--SWMGSYWSW......DPQHHGD......-PP.GPYLKK.AA.VVPIA.A.L..V...AMAV..A.GIRRMRAVA..VSQA.VMF.I.V..I.CGTTLc...lkAPGERVY.E..D.S..YR-..-......---.----.....---..-..--------nachagmgcgddspt.......
A0A6G2BCV3_9ACTN/21-156              ............rgdavs------GVLVGFVLLLAEVA.-...G.A.....LVVM......VGLGLRNWTDAgghregGGPGEPP......PMD.WVPVLW.CG.GFALA.V.L..A...LAVV..F.LRAGRPGVG..AVQL.LVF.A.A..A.LTATV......LTWHGEH.E..R.A..HPD..P......PPA.SPYRddpggRPC..L..SGGDSREC......................
A0A1Z2LC57_9ACTN/29-144              ..................RTRRGVDLAFAIPLFLLETA.W...L.V.....LDWM......FGLGLEVWAAQ......GERERID......AAR.LAHLGR.VR.VLLIA.V.L..V...TAVL..A.GIFRARWTV..IAHL.LVA.L.L..A.GGVLV......-VAQHQW.D..S.G..HAP..S......---.----.....PGC..V..RYS--AHC......................
A0A0A1DPB4_NOCSI/1-116               ..........mlaslgav--------------------.-...V.V.....IVLLpl..qyLGAHLCAW---......GECAVPG......PDE.IRTFRV.LAgVLAVA.V.V..T...TLAL..A.VRRRARLAV..AGHA.VVG.V.VglV.AALVF......AMPGIDW.A..G.L..RQD..E......PPA.RNPD....yVPC..Y..SGS--DDC......................
A0A1H8LHR0_9ACTN/1-100               ........mviflswslg--------------------.-...-.-.....----......------TYGS-......WDPQHVG......PRA.GGYVTA.MG.AVAGL.A.A..V...AAVA..A.AARRARRFA..WSQA.VVF.G.V..V.AAVMAg...thTVGTREY.E..Q.R..QRE..A......CQA.GLHA.....SYC..T..--------glt...................
A0A1X4GRK8_9ACTN/21-139              ..................RADLGADIGAGCGLVFLELI.A...L.V.....VIFWl....wFLSGFNLDPG-......-RAVTAD......-SL.WGYLAA.AG.GVGVL.A.V..A...AAAI..A.ARAGAAVTV..VSQA.FMA.A.L..I.CVIVFg...gaAAQSHQD.R..L.C..RDS..P......SV-.----.....TGC..K..GG------dd....................
A0A429QMA4_9ACTN/1-93                ..................--------------------.-...-.-.....----......----MEVWAAQ......GQVERIE......AAE.LAELAW.LS.SYLVV.V.L..G...LAGA..A.ALFRARWSV..VLQL.LAA.L.A..V.AAVLA......-LAQHDW.D..R.A..HPE..P......PPR.SGPA....yVPC..H..SGS--GRC......................
A0A1Z1W665_9ACTN/20-149              ................ga--DGRADITAAVGLFLVEGA.V...L.V.....VVFGa....wLLSGVSFFPAG......GAEVEPD......-SL.GGYLVA.AG.AVGLF.A.V..L...AAAL..A.FRRRAVATA..WSQG.LMA.V.L..V.AAAVWc...gpAYPDRTG.E..R.E..RPA..P......AST.WQGQ.....VGC..R..SGGDSDEC......................
S2XX58_9ACTN/1-88                    .................m------------ALLVIDLM.V...V.A.....YLLF......FRYGMTGWADG......YDSGNPP......EAP.GEALRG.MW.LLAGG.A.V..V...SGGG..L.VVLGWRMPG..VVQL.VVL.G.T..G.AGLLA......-------.-..-.-..---..-......---.----.....---..-..--------cpaarg................
A0A4V5MJ79_9ACTN/8-119               ..............tgrr---------TAVALAVIELA.V...L.A.....FIGL......SWASTYYWSW-......-DPQHYG......DPP.GPYLKK.AA.VVPIF.A.L..V...AAVV..A.AVRRVRSVA..VGQA.VMF.V.V..I.CGVMLc...agP------.-..-.-..---..-......---.----.....---..-..--------agesayedsyrnachagvicdg
A0A1G9MXX7_9ACTN/9-142               ..........radrrggr--------VLALVLSTIGWI.V...L.A.....FGLFa...waFLANFCLDAQT......CEELRSD.....gVAE.W-P-IA.VG.ISLGA.L.A..V...LAVL..P.FALRMPKTG..AVYA.AAV.L.A..V.LILLA.....qSGAARET.A..R.DllRDD..P......PA-.GE-Ydp.gpQPClpR..SGG-DAEC......................
V6JK57_STRRC/21-127                  ..................RADTGADIGAGCGPVFLELT.V...L.V.....ADFGl....wFLSWVTLDTA-......-RTVRAD......-SP.WGCLTG.AA.AVAAF.A.L..V...AALV..A.ARARAIVTV..VSQM.VMA.V.L..I.TLVVP......AAA----.-..-.-..---..-......---.----.....---..-..--------lgqahedgsagn..........
A0A4P7SP87_9CELL/26-149              ..........rtsrgpsr--------ARPLASLCLTLG.A...I.L.....VAAV......FVQWWDVYFSI.....gVPANAPT.....eAEA.NRYVVT.AG.ACLLL.L.V..V...GTVA..A.R--RYVLTAfgMVPF.VVG.V.A..V.AALFA......-VPSDRW.E..R.-..EPP..P......PPA.DR--.....PIC..R..SGGGSDDC......................
A0A367HRE1_9ACTN/1-108               ...............mie------------------IA.-...V.G.....LGRA......LSEGMDVWAAQ......GDRTRID......ASH.LADIAW.LE.YFLGA.I.V..L...LVVI..A.ALSRAPWTV..VLQI.LAA.A.L..V.AVLLA......-LTQHDY.D..K.S..HPG..P......PPA.PNPH....yTPC..Y..SGS--GRC......................
A0A0F2TD49_STRR3/1-112               .................m-------------LFLVVLA.L...V.Y.....VGRM......FGYGMDLWAAS......GEQGAAD......RVA.RGQLSF.TW.GLLGA.A.L..G...AAGL..A.ALLRARWTA..GLQL.FGA.A.V..L.FVFAV......-QLGHAY.N..R.S..HPA..P......PPP.PKPG....yTPC..Y..SGS--GRC......................
A0A250VW31_STROL/17-132              ..................RTRLGADVALAIPLFLLETA.W...L.V.....LDWM......FGLGMEVWAAQ......GDKAQVD......AAT.LAHINR.VW.VLLVA.V.L..I...VAVL..A.GLFRAPWTA..IAHL.LVA.L.L..A.GLILG......-ATQHQW.D..T.D..HAP..S......---.----.....PGC..I..RYS--ANC......................
A0A6B3I0Z1_9ACTN/24-147              ............gplaqf--------GVALGLVVLETA.S...A.A.....AVLLf....wFGAALHLDTG-......--TPAPE......VSP.TPYLLA.LA.AIGLC.A.G..A...AAFA..S.GRRREWGVA..VTQG.LMA.VsL..I.GAALVg....aTLETRGA.A..R.D..QPP..P......AA-.-PGV.....AGC..R..SGDDSREC......................
A0A2K8PFS6_STRLA/16-144              ...............gsh---WIADIARALLLTLLEAV.A...V.T.....AGL-......YVAAIAAWDTQ......GGGDDPR......--T.VVIVLL.VG.LLLAA.V.A..T...AVVSgrA.FRRRAPVTG..CVQA.LVC.A.A..L.LAGAAg....iAYQSRDHlG..Q.Q..TPA..P......SSP.YRGT....yGQC..F..SGGDSHEC......................
A0A561EQ98_9ACTN/26-145              ..............rgpl-----VDLLLTVVLVALEGA.-...L.A.....VVGL......YALLIRAWDT-......GGSTGPK......PYD.WVPVLA.VA.GFAAG.L.L..L...VTVL..A.CRSRLPITA..TVHGmLLA.G.L..L.LLVAG......GYAYDHR.H..D.T..RPT..P......--L.PSDY.....RPC..F..SGS--NDC......................
A0A2M9J4N2_9ACTN/1-109               .................m-------------LVLLELV.A...L.A.....ICVVa...wpFIDHFELDPQ-......-APQHPY......-VF.WDYAPA.IA.VLGAV.V.V..V...VGVV..A.VKGRATITA..VSQL.LIA.L.L..V.AAVLAv...gsAAQLH-E.D..K.R..QSA..P......EPA.GR--.....---..-..--------vltgatd...............
A0A1K2FPL4_9ACTN/17-131              ..................RTRPGADLALAIPLFLLETA.W...L.V.....LDWL......YGYGLDVWAAQ......GDRAEID......AAA.LTHIGR.LR.VLLIT.A.L..V...LAVL..A.AVFRARWTV..VAHL.LVA.L.L..A.GGSLM......-AAQQEW.D..H.S..HTP..P......---.----.....-GC..V..RYS--ANC......................
Q7AKK7_STRCO/33-155                  ..................RADLGADIGAGCGLVVLELI.A...L.V.....VVLGl....wFLSGFNLDPA-......-ESAAPD......-PL.WNYVAA.VG.GVGAF.A.G..V...AAAV..A.ARAGAVVTV..VGQA.VVV.G.L..V.CAVVFg...gvALQSHQD.Q..R.C..REM..P......AA-.----.....TGC..T..GSGRGG--sp....................
A0A420UV43_9ACTN/6-103               ...............epp---TGRQAGVSLALLVIDLM.-...V.I.....AWLL......FRYGVAGWADG......YDPGNPP......DAP.GEALRG.VW.ILAGG.A.V..V...TGGG..L.LRLRWRIPG..IVQL.VVL.G.A..G.AGLLA......-------.-..-.-..---..-......---.----.....---..-..--------llpaae................
A0A1E5P070_9ACTN/8-105               ...............eps---TGQQVGVGVALLIPDLM.-...A.I.....AWLV......FGYGMAGWADG......YDQDSVP......GAP.KVAWQG.MW.ILVGG.A.V..I...TGGG..F.LALRWRVTG..IMQA.LVL.G.I..G.AGLLA......ALA----.-..-.-..---..-......---.----.....---..-..--------lsd...................
A0A4R7MLU2_9ACTN/20-133              ..................RARLGLDLFASVALILLEGQ.-...V.L.....LWLA......FAAGMQAWATR......PGTPST-......AAT.PTEDHR.ID.YLLYA.A.L..V...AAAV..A.ALRRARWTA..GSQL.AVA.C.A..L.AVMAT......-SAQHDY.D..Q.Q..RQQ..Q......AA-.----.....---..-..--------grsaslta..............
A0A1Q5JZE8_9ACTN/17-132              ..................RTRLGVDLALAIPLFLLETA.W...L.V.....LDWT......YGYGLEVWAAQ......GEQARID......AAG.LAHIGR.VR.MLLIA.V.L..V...LAVL..A.ALFRARWTV..ITHL.LVA.L.L..A.GGSLT......-AAQQEW.D..D.S..HTS..P......---.----.....PGC..I..RYS--ANC......................
A0A2D3U3G8_STRC0/161-290             .................w-LHLAADIALAIGLLVVDVI.T...P.F.....ITFL......FGLDAAGYTM-......FDAAADNs....sVSL.TRPFTY.VA.VVGGI.V.L..I...SAFL..L.FLARAFVSS..GVQV.LAG.L.V..L.VLVAV......VGMNDAD.R..K.A..HPQ..P......APT.SPSIn..pgALC..R..SGGDNSEC......................
A0A2N0JIT5_9ACTN/23-139              ............qfspig------DMAWGVSCTVLEVV.L...A.L.....GGVI......---FIDLRPHS......RPYAGPG......VP-.PQVTHW.FV.ALIAV.A.L..V...IAAV..G.VRRKARWTA..GLLA.GAA.V.V..L.LVLLA......--A--MY.A..G.S..PKP..P......QPA.PPNP....gPVC..F..SGS--NTC......................
A0A2N0JV07_9ACTN/5-124               .................r-PQPVADLLLMLALVALQAL.-...A.G.....WWTL......LVLGLHGWAEP......EQAAAPS......---.-TPYRV.LG.GFALA.A.L..V...VAVL..A.GRRRLWITA..TVHGlLVA.A.L..A.VGALA......AHASDVR.D..R.E..RLR..P......HSL.PSGH.....LPC..H..SGS--GNC......................
V4IXK0_9ACTN/3-124                   .............plaqf--------GMALGLIVLEVA.L...T.A.....AALLv....wFFAALHLDTG-......--TPAPE......VSP.APYLLA.VV.AIGVG.A.G..A...AAVT..W.GGRRAWGVA..VTQG.LMA.A.L..LtCGALAg....lAYEARDA.A..P.E..QPA..P......AP-.--GV.....VGC..R..SGDHSQEC......................
A0A498AWI6_9ACTN/1-109               .................m--------------LLIEIP.-...I.A.....ILLG......LTLGIRGWGRA......EEQSGAP......TTD.WVPVLW.LG.GFTLG.V.L..V...VAAA..F.LLSAHPYAG..AVQL.LIA.T.V..A.MICTM......HAWHGEY.V..R.A..YVSslP......ACP.TRAD.....TFC..A..SS------e.....................
A0A2M9IL57_9ACTN/1-109               .................m--------------LLIEIP.-...V.A.....ILLG......LTLAIRGWGRA......DEQTGTP......TMD.WVPVLW.FG.GFTLG.V.L..V...IAVV..F.LYLAHPFAG..AVQL.LIA.A.I..A.LIFTM......SAWHEQY.E..R.A..HPS..P......LPA.CPTRa...gTPC..V..S-------pn....................
A0A2S4Y648_9ACTN/1-111               .................m------DLALAIPLFLLEAA.W...L.V.....LDWI......YGYGLEVWAAQ......GDKAGID......AAG.LAHIER.LR.VLLIA.V.L..V...LAVV..A.AVFRARWTV..IAHL.LVA.L.L..A.GGSLT......-AAQHEW.D..Q.S..HTP..P......---.----.....AGC..V..RYS--ANC......................
A0A176KT76_9ACTN/21-137              ..................RADRGADIGAGCGLVFLELI.A...L.A.....VIFGl....wFLSGFNLDPG-......-KTATTD......-SL.WNYLAA.AG.GVGVL.A.I..V...AAAI..A.ARAGAAVTV..VTQA.VMA.A.L..I.CVIVVg...gaAAQSHQD.R..L.C..RDM..P......SA-.----.....AGC..-..--------kgn...................
A0A1D7VL53_9ACTN/17-132              ..................RTRLGVDLALAIPLFLLETA.W...L.V.....LDWM......YGFGLEVWAAQ......GDRAQID......AAG.LAHMGR.VR.TLLIA.V.L..V...LAVL..A.AVCRARWTV..IAHL.LVA.L.L..A.GGVLV......-AAQQEW.D..H.S..HAP..S......---.----.....PGC..S..RYS--ANC......................
A0A2M9CNH0_9MICO/152-276             .........dsrpraagv---------VTILLLLGGAAaA...L.L.....LMLQ.....yLEVYFTIWGE-......SDRPSPG......-EE.ARYLLT.GG.TALALgV.AgtV...VAAV..R.RRTRAVITG..IAVV.LLT.V.A..L.AGVFA......-VPQGRW.T..P.-..--E..P......APVvDDGY.....VPC..F..GEG-DPNC......................
A0A4V3EZB7_9ACTN/34-157              ..................RVNLAIDIALAVTLLGAQAL.-...A.Y.....LWRM......FTLGMEEWAQ-......GPDANPD......TST.LTRIAW.TQ.GLLIA.A.L..V...LAVL..A.AALRAPFLA..LAQV.IAG.L.T..L.LALLG......-AAQHGY.D..R.T..HPK..P......APT.PSVY....yTPC..Y..SGSHGPSC......................
A0A0X3XMH2_9ACTN/21-138              ..................RADRGADVGAGCGLVLLELV.S...L.V.....VIFGl....wFLSGFHLDPA-......-DSASTD......-PL.WTYLAG.AG.AVGVL.A.V..V...AAAV..A.ARAGAVVTV..VSQA.VMA.L.L..I.CLVVFg...gvAVQSHQD.Q..R.C..RDV..P......SAT.----.....-GC..G..--------dag...................
S4A7M1_9ACTN/20-147                  ..................RADLGPDVATAVGLFLLEGA.F...L.C.....VVFGm....wFLSGFSLDPA-......-ADTEPD......-RL.GGYLVA.AG.AAGLF.A.V..L...AVVA..A.RRMRAVVTL..WTQA.LMA.A.L..V.TVAVLg...gmEYQERVD.R..R.S..EPV..P......AST.WTGP.....VGC..R..SGGGSDEC......................
A0A1Q9TQE9_9ACTN/6-104               ..................RPSRGEQVGASVALLAIDLM.V...I.A.....WLVL......IQYGMAGWADS......YDSGNPP......RAP.QEALRG.MW.ILAGG.A.V..V...TGGG..L.LALGWRIPG..LVQL.VVL.G.V..G.AGLLA......YLAA---.-..-.-..---..-......---.----.....---..-..--------rg....................
A0A1C5BE11_9ACTN/39-168              ..............vngc-----LDVLLGLLLVVLEGL.I...C.A.....AAAY......YLTFSQWDPDG......QESTEPP......PMD.WTPVLV.FG.AIAVV.I.C..L...FAVV..L.IRANRPWAG..AVQI.LAA.L.L..L.CVVTA......LAGHEDY.R..R.S..HPA..P......AST.PSYDpgrsgHQC..L..SGGDSREC......................
A0A223S7V8_9ACTN/1-121               .................m--------------FLLEAG.A...V.V.....VIGYialiagLGEALNGAAGG......SGSEGLT......-RQ.DSALIA.LG.VLGLL.A.A..G...AAVL..F.FRGRWRIAG..VTQV.LVA.M.A..L.VVVVVg....gAVATHRP.E..S.-..-PA..P......GHG.DEYTg..pgGQC..R..SGGDSEEC......................
A0A2G7F010_9ACTN/17-132              ..................RTRLGVDLALAIPLFLLEAG.W...L.V.....LDWM......YGYGLEVWAAQ......GDQAQID......AAG.LAHMER.LR.VLQIV.V.L..G...LAVV..A.GGFRARWTV..IAHL.LVA.L.L..A.GGALT......-AARHEW.N..H.D..HSP..P......---.----.....PGC..V..RYS--AGC......................
F4H5W1_CELFA/166-290                 ....pwrgtavvrgveva----------GLGLGVLLVV.A...L.F.....FQF-......LDVNLSLYGDQ......PPPTAAD......--G.SRYVVT.AV.ACLSL.V.L..A...GTVA..A.GVGRHIGVL..GLGI.VLL.L.V..A.AVAAV......VLAVPGD.R..F.E..YEP..P......RQE.RPAY.....EPC..Y..SGS--GDC......................
A0A1V9K2F9_9ACTN/17-136              .........rrdgfaggc---------IGLIALLIEIP.-...I.G.....LLLG......LAVALRGWGDT......QARTAAP......TVD.WAPIVW.CG.GFTLA.V.L..L...IAGL..S.LYMGHPFAG..VLQL.LLA.A.V..A.LAITL......AVWHDQQ.A..Q.Q..HRA..S......VTT.VQP-.....---..-..--------arqvsppr..............
A0A1H7YDE0_STRJI/19-143              .................l-APVAPDIALGFALLVLDAM.-...A.Y.....LWQE......VRYDVVGWAGG......VPRATLD......ADQ.LTGIAF.ME.HLVIA.V.L..V...VAGL..A.LLLRAPWTL..ASQG.LAA.V.A..L.LLLLS......-VAQKDY.A..D.S..HPA..P......TPT.PSIV....vAPC..Y..SGSHGPTC......................
A0A1C5C2Y3_9ACTN/38-162              ............dwfegg--------CLGLLMLLLETL.-...F.A.....LMLG......VALGLRTWARPgeyansKARVATP......PMD.WVPTLW.TA.GFTLA.V.L..A...IAII..F.FRAAHPFAG..SVQL.LVA.A.L..A.LCVTV......AAWHDSY.E..R.A..HPA..P......LPP.CPTRa...gTPC..-..--------ape...................
A0A2X0IUP6_9ACTN/1-120               .................m------DIPTAVALFIVEGL.-...L.Y.....VASE......FMAVIGAAFS-......EPSAELD......AAF.RAGLDR.TW.WLLIA.A.V..A...FAVL..A.GFLRAPVVV..VSQV.LAA.V.I..L.AVLLG......-LAYRSY.D..E.A..HPP..P......-PT.PGPTt..ayEPC..Y..SGSHGPSC......................
A0A4R7H2R3_9ACTN/21-136              ..................RADRGADIGAGCGLALLELI.A...L.V.....VIFGl....wFLSGVTLDPD-......-TAVEAD......-SL.WGYLAA.AG.GVGVL.A.V..V...SAAI..A.ARVGATVTV..VSQG.VMA.A.L..I.CLLIFg...gaTAQSHED.A..T.C..RAT..P......AA-.----.....PGC..-..--------dg....................
A0A1C5G8A4_9ACTN/8-137               ............arprya-------------LVLLTAL.W...V.VaclalLWWL......FTIGMEGWADHh...snGDARAAEi...grRSA.RALLLL.TV.VAAGG.A.A..V...IALV..A.FGCRYRRTA..LVYA.FLA.V.V..I.TAALT.....pA--VADA.A..R.S..LRP..P......AAP.VPAP.....TTC..QehSGG-DSRC......................
A0A1Q5L3S2_9ACTN/7-116               .............rsgrg---------AATVLIVVELA.V...L.A.....VIWL......-SWAATYWSW-......-DPQSYG......DRP.GPYLRK.AA.FVPAA.A.L..V...LAVV..A.ALRRARTVA..ISQL.VLA.A.A..V.CGLIL......-GAKGAG.E..R.A..---..-......---.----.....---..-..--------yessyrdacragvlc.......
A0A1C5K448_9ACTN/1-120               ................ml--------------LWIGGL.L...A.A.....GWWL......FSIGMEQWAASys.ppdAASAELE.....rRAS.RAGTTL.VL.VVAGG.P.L..V...IALV..A.YGMRLVRTA..VVFL.VLT.L.L..L.GGPALv...lgAAANR--.D..R.Q..PPV..P......PPS.APGH.....CVE..L..SGG-DTRC......................
A0A0G3UZ55_9ACTN/21-144              ..................RTPLGRDIALGIVLFVVEAA.-...V.H.....FSVR......FGHGMEMWAAQ......GDETRIE......AAR.LADLAW.MQ.HFLVA.M.I..V...FVVI..A.LLFRAPWTV..LSQL.LAA.A.A..A.AALLV......-LAQHDY.D..L.S..HPR..P......APA.PSPG....ySPC..Y..SGS--GRCn.....................
A0A1H7TQM6_STRJI/19-142              ..................RAPLPVDVVASCVLLGVEVL.-...L.Y.....VWLW......LGGGLQIWAAG......DDSASVD......ATL.RTELAR.TQ.WLLFA.A.L..A...LVVV..A.AVLRAPWTF..GSQL.LAA.A.A..L.TVLLT......-LAQQGY.D..R.T..HPT..P......APA.PTGD....hQPC..Y..SGS--GTCn.....................
E4N0S3_KITSK/20-141                  ..................RMPLGADFGLFLVLFSAELV.A...F.V.....LL--......----VRAQPHD......GPFAVVS......EVT.RSFLVW.QG.VLVLA.A.A..V...LAGL..A.LYLRAPLAA..GSQV.LGV.L.V..F.AGLLL......-LSLRGY.S..H.P..YPA..PhsvplqGPA.SAGA.....TAC..R..SGS-----lc....................
A0A101J5V5_9ACTN/29-141              ...............slp---AAGDMALAVGLLVLDVV.A...V.V.....AAFL......LGIDVSGDWEP......FDPGADNs....dVTL.TLNWLY.VG.IAGGL.V.L..L...SAAP..L.YWLRAVVSA..GLQV.LVG.I.A..V.LIVAV......SGAQYDE.E..Q.-..---..-......---.----.....---..-..--------gartdasva.............
D5UHU4_CELFN/24-147                  ...............rrg---RVPRLVAGLCLTVGSLL.A...V.L.....LFFQ......YLATYFVFFGD......VEVATPD......QAT.RYVVTA.TA.CLTLL.L.A..G...TAAA..I.ARGRLGLSV..LALV.--L.T.L..A.GVVVVa...lfPVPNDRW.E..R.-..EPE..P......RPA.-NLG.....PVC..Y..SGSDC---se....................
A0A1C4ZUE5_MICEC/7-137               ................th--RRAGTVALLTVLWLLAAL.-...V.L.....LGWT......FAIGIQGWADQhg.sggADPAGAS.....rRGS.WVLLAL.YL.TAAGG.P.V..V...IAVV..A.FAGRLVRTG..AVYL.ALA.L.L..L.GAFGMp...fgE----AA.A..R.D..LVP..P......PPV.PSGP.....GGC..Q..EHSGG---dtrc..................
A0A0C2AHI4_9ACTN/21-146              ..................RPTRGADAFLAFVVLVGDAM.L...L.G.....IGTL......LLIFAQLDVGPr...dlPPRTVPE......-MD.WAPLLS.YG.VPVLL.I.A..L...SVWW..F.VRSRHPITV..CVQV.LVV.L.V..V.GGAML......AVTARAY.Q..H.A..HPP..P......RPP.QRHY.....VPC..Y..SGS--GDC......................
V6KMD2_STRNV/1-61                    .................m--------------------.-...I.V.....VVWP......FLDHFDLDPA-......--SDTET......VSL.WRYLPA.LG.GVAVV.A.F..V...ATVL..A.GRARATVTV..VSQA.---.-.-..-.-----......-------.-..-.-..---..-......---.----.....---..-..--------hq....................
A0A327WD05_9ACTN/8-106               ...............eps---TGEQVGVSAALLVIDLM.A...I.A.....YLLL......LRYGMTGWADA......HDRAHPP......NAP.SEALRG.MW.LLLGG.A.V..A...TGGG..L.LALGWRIPG..VLQL.IVL.G.V..G.AGLLA......-------.-..-.-..---..-......---.----.....---..-..--------cfaarg................
S5UUP6_STRC3/21-79                   ..................RADRGADIGAGCGLVVLELG.A...L.A.....VIFGr....wFLSGFALDTA-......-ESVAAD......-PV.RGYLVA.AG.AVG--.-.-..-...----..-.---------..----.---.-.-..-.-----......-------.-..-.-..---..-......---.----.....---..-..--------g.....................
A0A197SVB0_9ACTN/21-136              ..................RTDTGVDIGVSCGLVCVELL.T...L.V.....VTFGl....wFLSGLDLDPG-......-ATVESD......-SL.WGYLAA.VG.AVGVF.S.T..V...AAAF..A.ARAGAFVTV..ISQA.TVA.T.L..V.CVIVFg...gtMAQSHED.A..R.C..RDT..P......SAA.S---.....---..-..--------ced...................
A0A1Q4WH14_9ACTN/1-110               .................m------DLALAIPLFVLETA.W...L.V.....LDWM......FGLGLEVWAAQ......GRQDRVD......AAA.LAHSGR.VT.VLLVA.A.L..V...MTAL..T.GVFRARWTA..VAHL.LVA.L.L..A.GGVLM......-IGQHEW.E..R.S..HTP..P......---.----.....-GC..V..RHA--ANC......................
A0A2S0WM33_9ACTN/14-134              ..rsrlvsgfclgvgifs--------------------.T...L.A.....LVWQ......FTEVYFVFGE-......--VADPT......ASQvHRYVWT.AS.ICITA.M.V..V...SAVA..A.LVAGSRWLG..VPAT.IGV.V.L..A.VVVSFv....fAVPSDRW.-..-.-..KPD..P......-PT.YELPa..nyDPC..Y..SGSDSC--gp....................
A0A1K2FW02_9ACTN/21-137              ..................RADLGADIGVGCALLLLELI.A...L.A.....GIFWl....wFLTGFDLDPA-......--ETATA......APL.WPYLAA.VG.GVGVL.A.V..V...ATAI..A.ARAGALVTV..VTQA.VVV.V.L..T.AVVVFg...gaTAQSHQD.R..L.C..RDT..P......SA-.----.....AGC..R..--------dd....................
A0A1B6AJB3_9ACTN/18-113              ................gp--SRGTDIGVAIALLVLDIL.-...L.V.....GWLL......YGYGITGWADG.....ySPNREPE......APD.VARTA-.IW.ILLGG.S.V..V...SGGG..L.LYLRCWVAG..VTQF.LVL.G.A..G.AML--......-------.-..-.-..---..-......---.----.....---..-..--------fasmpl................
A0A0Q5C8Z9_9MICO/13-135              ...........qpighag-------IQAGLGVLGSSIM.A...A.L.....AW--......--QFFDVYFAIg...gtVPTAAPS......-DG.LRYLVT.AG.VGATV.V.A..A...SLVL..A.LLRRKGLAV.vCSLA.LSI.G.M..F.GFAYV.....lAVPQNRW.N..Q.-..DPV..H......EPL.PADY.....RPC..F..SGS--NDC......................
A0A561UAG8_9ACTN/23-137              ...............tvg---TVTDVLLGLGLLSLIGI.A...T.L.....VGV-......FCNAMALWSN-......SEDARRD......---.LGRFAWwLV.VVLAV.A.V..A...IAVL..A.ARKGARWTA..RIHF.GAS.G.V..L.ALLLL......-LAAG-P.L..T.A..PPN..V......ALA.YRPV.....TVC..P..SGG-----......................
A0A4R3D6I8_9ACTN/18-115              ................kp--PTGQQVGLGMALLLIDLL.-...I.I.....AWLL......YGYGMTGWADS......YDGVNAP......QAP.EVARHA.AW.LLGGG.A.V..V...TGGG..L.IALRWRVSG..LMQL.TVL.G.G..A.AMLF-......-------.-..-.-..---..-......---.----.....---..-..--------aglagrs...............
A0A0Q8Q263_9ACTN/8-130               .........rpagaaeas---------ASIAAILLTFA.-...-.V.....AWHG......FGVYFCLGAHC......SGP--SD......QEI.LTYRLL.AG.ALGVA.V.L..A...SLAL..A.ARRRATLAF..VWHL.AVT.A.L..A.AAVALl....fAVPQIDF.R..ElT..EPE..P......PAE.NPSY.....VPC..H..SGS--NDC......................
A0A2N5WUE7_9ACTN/9-100               ...............psa----GRQAGVAAVLLLIDLM.-...V.I.....AWLL......YGYGITGWADG......YDDADAP......EAP.RAALRA.TW.ILAGG.A.A..V...TGGA..L.LASRWRVPG..AVQL.LVL.-.-..-.-----......-------.-..-.-..---..-......---.----.....---..-..--------gggaamfal.............
A0A2I0SY91_9ACTN/21-137              ..................RADRGADIGAGCGLVLLELI.A...L.A.....VIFGl....wFLSGFDLDPG-......--RTVTS......DSL.WEYLAA.AG.GVGLL.A.I..A...AAVI..A.ARVGAVVTV..AAQA.VMA.V.L..V.CALVLg...gaAVQSHQD.R..L.C..RDM..P......SA-.----.....V--..-..--------sckgd.................
A0A0M9ZNA7_9ACTN/21-143              ..................RADAGVDIAVGCGLAFLELT.A...L.A.....VIFGl....wFLSGVTLDTA-......-KTVKAD......-PL.WGCLTA.AG.AVGAC.A.L..V...AALA..A.ARARAVVTV..AGQG.VMA.L.L..I.SAVVFa...gaKAQAHDD.AtvR.T..HEH..T......CRT.TPAT.....PGC..R..--------g.....................
A0A0F0HYB5_9PSEU/1-122               .................m--------AIALTLFAVSVI.A...A.A.....VAAGag..flWLLGNTDWMP-......DSTPRPE......-PS.RAPLWWiLA.ALVAL.V.L..L...LGVG..A.AVRRYRIAA..AVQF.VLAaV.L..V.MGGLGt....yAYEHRHD.G..E.R..KPQ..P......LPA.--NY.....RPC..Y..SGS--NTCn.....................
#=GC seq_cons                        ........................phshuhsLhllEhh.h...l.s.....lhhh......ahhuhphass........ssspss.......ss.hshlht.hu.slsss.s.l..l...sAsl..A.hhtRthhos..ssQh.lsA.s.l..h.ssllh.......htppt..p..p.t..pss..P...................ssC..h..phs...........................
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