GenomeNet

Database: Pfam
Entry: DUF6365
LinkDB: DUF6365
Original site: DUF6365 
#=GF ID   DUF6365
#=GF AC   PF19892.2
#=GF DE   Family of unknown function (DUF6365)
#=GF AU   Williams LS;0000-0001-5551-8526
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Fragoso S;0000-0001-7018-3891
#=GF SE   Manual
#=GF GA   32.50 32.50;
#=GF TC   42.80 35.30;
#=GF NC   29.90 29.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   30830740
#=GF RT   Bioactivity-HiTES Unveils Cryptic Antibiotics Encoded in
#=GF RT   Actinomycete Bacteria.
#=GF RA   Moon K, Xu F, Zhang C, Seyedsayamdost MR;
#=GF RL   ACS Chem Biol. 2019;14:767-774.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a member of a biosynthetic gene cluster
#=GF CC   (BGC). This BGC (BGC0001960) is described by MIBiG as an example
#=GF CC   of the following biosynthetic class, polyketide, in particular
#=GF CC   the hiroshidine biosynthetic gene cluster from Streptomyces 
#=GF CC   hiroshimensis [1].
#=GF SQ   21
#=GS A0A1H9ZTE7_9FIRM/22-406   AC A0A1H9ZTE7.1
#=GS W7JB98_9PSEU/22-423       AC W7JB98.1
#=GS A0A1H9ZT31_9FIRM/23-424   AC A0A1H9ZT31.1
#=GS A0A265Q9J6_9FIRM/23-423   AC A0A265Q9J6.1
#=GS A0A1K1TGD4_9BACL/22-440   AC A0A1K1TGD4.1
#=GS A0A495W2K2_9PSEU/22-426   AC A0A495W2K2.1
#=GS A0A1B9EVX5_9ACTN/22-400   AC A0A1B9EVX5.1
#=GS A0A0S9DNP7_9MICO/26-423   AC A0A0S9DNP7.1
#=GS A0A4U7JHC3_9FIRM/23-417   AC A0A4U7JHC3.1
#=GS A0A265QA56_9FIRM/22-401   AC A0A265QA56.1
#=GS A0A4U7JLG0_9FIRM/22-412   AC A0A4U7JLG0.1
#=GS A0A2N5XHU0_9ACTN/22-415   AC A0A2N5XHU0.1
#=GS W4VBM9_9FIRM/1-292        AC W4VBM9.1
#=GS A0A326TZF3_9CHLR/22-438   AC A0A326TZF3.1
#=GS A0A495XSR6_9PSEU/22-419   AC A0A495XSR6.1
#=GS A0A5M6CIC3_9BACT/173-388  AC A0A5M6CIC3.1
#=GS W4V273_9FIRM/24-415       AC W4V273.1
#=GS A0A1Q4Y5P9_9PSEU/22-419   AC A0A1Q4Y5P9.1
#=GS A0A6B2V197_9ACTN/22-421   AC A0A6B2V197.1
#=GS A0A3P3W435_9MICO/24-426   AC A0A3P3W435.1
#=GS A0A4R2JSX0_9PSEU/22-419   AC A0A4R2JSX0.1
A0A1H9ZTE7_9FIRM/22-406              ..FAEELKNLQNRVLFIIPPTHKKNVEAKG.FK.YVTWIPK...SRKFNQIILAEVEHSFCPEVVILSD.....FLNYSFA.DKHYGILREDLD-----IFGGKLATFDIYNWSLERKCMD...............TYGFVSPIPNKVDIKDYGAKILPCPLINPE.......NKENELGYRYSVVH..KLLDTSQK...NKEELRKKYGF.HVNEKIILVSYAKWQESHIQN.......-.--EKVGHFIDFSGRLFDELIIQLSFYYTIICIGKETEGFRD---.--YSNIHC..YDSMPAKQFDEYAMTADLYIGKNMTSTSMIRLALSEIMCVNIINSIV.FPHKIEE....----KSFG.NFNYAAEL-....---EDIHMYKYMMLPVGWYEFLKPVFQNNPYADIVCMREQFKMNETMEVIHELLF.NE....QERARITERVAALKCSLE.KLKSPIQIVNHIIN---e..................................
W7JB98_9PSEU/22-423                  ..LTNQLRAAGVRSHYVITASSENLLRHHG.YP.HTVLDPA...GGQDVRAEVDAVVRRFRPDAIVLAD.....YLNHWGTlIRQFDTDPWFID-----DYRLPVLPIDIWEWENTAFRFD...............VCGRRHEREVSRRILDMPAHLRPVPVCHLD.......PGPAGYGHPYRVLP..PEPALTAA...RRREVRAALGV.GERHRLVMLPMAAWQHQRGDR.......PgMTEMVGRLGRRVPELLADYLRRLPSDAHLLFIGGNVP--EPFLA.LPAERVHL..LPLCAPDRYDELLASVDAVLSLTTTGLTVSRAILADTPAMLLTNRFT.VPDTAAV....DTVESELG.GMDPVVRRW....LLDT-APVEPFRMWPKGQHAFLEPLLKDNPHLDALVHRELFDGGGVVAALTALLF.DP....GTRDDLAARRAGYAAAVA.ALPPTEEVFAAAAGRA-a..................................
A0A1H9ZT31_9FIRM/23-424              fe--SNLDKEKYCSHFIVPDGKTAVMKKEKtFPtFTISREK...SRSENREFLLNLIKEQQYDLILLFDvfifeYAQGWTG.----------LNMEELMELGIPIMSLDEYEYTKAGYQLD...............YYGMFRK-KLPPLLEQCDYVIKNCPLTMTSgpetslwQGEKKNEFYYRIFN..LRERVSDK...ERQEIRKKYAKaDGKSKIVFLTTSQWELQGAYS.......-.-FAAQNRVMKWLGIMVFEYLKLLDEDITLLHVGSSVNNIPA---.-KEGKVTYvyYDGLPVNEFEKVLQSVDLYVTFNLVSITLSKAIMFGIPSLVFNNAKI.IDYMRLE....KKVQEMPE.WYQEMAKDV....-----KKVYPFTASMFGWNYFLKTVLEDNPYVETFERVEFFSIRKTVEKLRCMLF.EE....LLRDELREKNKRFISQYE.SLLSSNEILNAIFEN--k..................................
A0A265Q9J6_9FIRM/23-423              ..FAKGLNKNQYSMDFLIPEEKNVFFE-KD.CE.FRVHTISrnyGVTHNQRHIISLIKSNNYDLIILFDaftmeYAQYWTG.----------INMDVLKALDIPISSLDEYDYINAGYKLD...............YYGIFVK-KLPDLLSEVDIILKNCPLSMPKggqdlikEAEEKGQFYYQVIQ..EIRKLDKN...HIFNIRKRY-V.KDDEKIVFLTLSKWELEGAYS.......-.-FTSQSTLCRYLLPLIYNYLSELDTKICLIHVG---DSCWNESE.FKNPKIKYihYSSLPVDIFEELLQSSDLFVTYNLVSITLTKAVDFGVPSIVLNNDKI.IDFKTLE....KKCMEKPL.WYQYMAKDL....-----KKIYPFTASMFGWNHFLKGIMKDNIYMKSFERIQVFNTEQVNSTLKEILYgDL....--CEKMIDNINIFKRELS.KIPNVNEVLNNAFQYL-l..................................
A0A1K1TGD4_9BACL/22-440              ..LARQLEEQDVRAHFLTSPNHIDYVRQAG.MS.ATSLR--...KATMQTAPIQALVEEFQPNAIVIAD.....-------.YHNLDLESPLIDLDYVLQLGIPCATIDSLSWAPNSRILRnrlfdgtinkrpnanIKGE----VHLREVPEQMKIIRTCPINSP-.......KDVGDRIKAVTLYK..EPFHIDED...VKQQMRQRFGCgHKDDKLVMVSKAAWASLLVKMrml.eskL.HMQASYSYEYFIQELIGQYLGTRSLPSKVVVVGIASEK-GFLER.DPHSKLSFvsLPFMDLDEYEDLLFSCDLFITDNITSCSMAKALFGYVPTLSLINTKV.VSSPDEGvpilP--QLSSE.PIKEILERW....SRVLPQGLYPFLTFPNGWVEELAPLLEDNPFFDAIDIAEMFCVDQTGEKIWNMLY.DE....STKQHILDKQERYIEKII.HLPGAMEMLCFITEQK-v..................................
A0A495W2K2_9PSEU/22-426              ..LAEQLRRAGVESHFVHPPVTSGAVEHFG.FD.HTVVDYAdcpKGPSARAFVDELVASVAPDAIVLCD.....YNVFIRNvRFHFQLDPVFID-----DYGLPVLPVDLMEWEDTDFEID...............LCGA-PPLPVDRGILAYPAHLRPVPPLHLD.......RGGSTRALPYRVVApeSVDPATSA...R---IRADLGL.GGRDRLVMLPVSAWQRPPGGR.......GlWSDMMTTLTDHVPDLVVRYLGRLPEHVHFLVIGQAPP---AFDR.LPAGRLHV..RPPCAIDRYTEYLGASDAVVLLSPPSVTGARAVLMDKPVLIMQNRFP.VRDGAEL....AAVAAEV-.DLTPFVRDW....LAAT-GPIDRFRMWPKGSFRALDAVFTANDYTNALITTELLDETGTVRALHDLVA.GPddpsGAAERLAKSRARYLEAVA.ALPDAVEVIREAVGR--gp.................................
A0A1B9EVX5_9ACTN/22-400              ..LAGQLAPAGITAHFVVDTHNAPQIRAAG.VP.GTVIDTA...MGAGVRKVIEDAVRAERPDVIVLSD.....YLSYWLMmHRVYRTDPWFVE-----RLNVPVIPLDLYEWENTDFRID...............HFGL--DLEVDRRILGMPVQLRPAPWARPD.......PGPGSRALTYPFMR..PLPRPTDE...ARRAVRSALGL.REGDRLLSLSVSGWQRYAQTV.......-.ENPVTRGLARQVPERVAAMLRRLSSTTRFLVIG---PDLEGLEG.LPAERTHR..VPACAPDRYQELLDASDAVLSLHVPASALVRSVFSDLPAVHIVHSGP.DTGAAHA....--------.---------....--EGPGGLEPYSMWPLRWNSVVRPLLSDNPLAAAFRRAELLDTEGTVEMLDAVLN.DP....WTRAGLSEARGRYLAALD.ALPPVPEIFAEAVHRA-s..................................
A0A0S9DNP7_9MICO/26-423              mg--RSLEAAGMTTRFIVTEQLADYAKASG.VD.VIVRS--...MRRNRGAEVVSTIEQLSPDLVVLAD.....-------.YHLPFLEPGAAGIQNLVSPVVPTVMLDSLGFGLSGAEVTntlag....lpgaeaLRRWFTPTTSIPHVENSQALLHPVPVATP-.......DAP----GSFSLYD..SVPEVGAE...R-RATRERYGV.EPGRALVVVAQSAWAATGFTQl....grTrGRQLGRSYDDLRIDWILHCLSLVGVD--LTVVGVRRDA-AARDR.YSNVSLVH..TPFLGLDDFSELLGAADLYVTDNILSAAMARAAVMGTPCLALVHELDgVAEPTDE....--FEQNW-.--HPDM---....RALFPGYDFPYLVNPFGWISEVGAMMPGNPYLQSVPRVDVFDSRAVSGAVRTQLS.TS....------------------.-----------------adtrptdvlrdpgaaraspvdvvrralarpsdllh
A0A4U7JHC3_9FIRM/23-417              fg--SRLDKNKCQVKFLVPSKFVSYLQERG.QD.YISLNIN..dGAFINKTIVDNLINSYKPDYILLSDiytieYSRL---.-------WSGVSMQMLKQYAIPILGIDEYEYLSTKCKPD...............YYGG-NFEILPPLLDDCDYVIRNCPLNINR.......TSQDQKVKCFSLYD..RDLELSIE...RKLEVRKKLGV.SECNKMIMYSSSSWESINFHD.......-.-MPSLGMLMKWLPTILHNYLKDLNVPITLVHVG---PNKWDIDI.NQCGKVTYmnFGYLNPTEFDECLLSSDLFITTNVVSVTLSKAIFGSIPCIVFQNYKN.IDFAKLQ....KTLLKRPE.WYQKMAKDI....-----KCVFPFRAGFFGWFRLLEAVLSDNEYTDTYEVVQLFKYDEVLEKLQEYLF.NE....DKVTVLKEKQKEYISKVL.KLTTPQQIIDEIEQ---erh................................
A0A265QA56_9FIRM/22-401              ..FADELIKSGEKICFIAPPTHKNTILKKG.YI.CISLVPK...SRQLNRILFNEVKYSFKPDLVILSD.....FLNYNFA.DRHYG-----ITKEDLNIFDTTLCTFDNFYWNYPRKCMD...............TYGFKSDIPKKIVLEDYGARIVPCPIVNPD.......SVEGENVYTYSLIS..DFVDISNL...KKRKNRIKYGFdNDEDKIILVSYAKWQNEHIED.......-.--RGVSEFVKLSNNFFNKLISKLAEEFHIICVG-------SKEK.IQGDNIHH..YSSVHTETFDELVSISNIYISRNMTSTSMVRIALSGVRCVNIINSIS.DIGTIEK....---IAAKD.EFNMTIKP-....--------YRYFMFPVGWYSFLKPIFDNNPYAELIIQIEQFEIERGIETIKDILYgDN....SDHTILTNK---LRRKLS.ELMTPKEIVRSILSYD-l..................................
A0A4U7JLG0_9FIRM/22-412              ..FAKRIKKFGYNPYFFIPPSHKNILQQEN.IN.YCVLIPN...IGSINRILFQDYENRCHPEYVILSD.....FLNYNFC.EKDYGLSV-----KDLEIFSGRIGTFDNFDWTIKLRKMD...............TYGFAASIASKVDINKYGFKLVPCPITNVN.......EQNEDDKFYYSLID..EYLEYDEE...KKIKMREELNL.PQKKPIILVTSATWQDTYKSY.......-.--PQIIKCVEIFNNVYARLIDKMSEKVTIVHVGKNSS---IKFK.NENKNIIY..LDNLSPKLFDKYCIACDVFLSRNITSTTLAKVACSGIPAMVLTNSLH.IKNGVVL....SSNSEITN.EMKKELEK-....----IDDLYPYRMFPVGWYSFLEPIHKNNPYFELVIEEEVFDFDKVLKSIDKMTN.DA....GYRAEIKEKAMQYRLTLE.NLKKPEEILS-------llnnrd.............................
A0A2N5XHU0_9ACTN/22-415              ..LADQLVPAGVKSHFVVDAGNEAMLRSSR.HA.YTTVTSA...LGRRVEDVVAGVVRDFAPDAIVLCD.....YTAHWMThVVSYDTDPWYVE-----RFGVPVIPIDLYDLTRTGREVE...............ILGR--TMRVSDRILHMEAHLWPVPGVRPH.......AAPDGPAFPYRADP..TVRPLSAA...ARQEVRDGLSV.HARHRLLTVPTLPWQHLMQTR.......-.AGPLTRELARRVPHLVAGYLAKLPDDTRFLFLG---PWFDGFDR.LPRERVRH..RPSCTAGEYTRLIGASDAVLALFLPSFALERAILADVPGLFTVNSHR.L-DPADA....---AGLPD.GLTPDVRSW....LSAFPGTVPPFHMWPLQWNRVVGPLLEDNPFTATAVRTELFDEEAVVSGLEAVLH.DT....ATRDALAAGRAGFRRAVD.LLPDTPDVFFAAARRV-g..................................
W4VBM9_9FIRM/1-292                   ..----------------------------.--.-------...-------------------------.....-------.-------------------------------------MD...............TYGFNAKTVSKVDITKFGFRLTPCPIANPL.......MKNENNKYYYPLLD..EFLPYNQD...IKIKHRKELNL.PQNKRIILITSAVWQETYKAY.......-.--PHVTNFVNAANKIYRNILTRIAQNNIVLYVG--PKG-FFEEG.NIPSNIHF..LGQLSPDVFEKYATASDLFITRNITSTTLAKLALSGIPSVMLKNSLF.FTPKTKD....-KFKCPF-.KPTEQVEEI....LNNL-EMCYPYRMYPVGWYTFLEPVIKDNPYINVVNEVELFDEERAVDTIWDILE.NR....ETVDRITENVARYRGMLD.KLCTPSNILEQI-----gyde...............................
A0A326TZF3_9CHLR/22-438              ..VAQQLQRRGAEVLFLTPPEQQAYAEAAG.MQ.VRVLPLK...----LHQQIQEVIEDFRPDAVVLAD.....-------.YYLLDIESEILDLEALLRLPVPCATFDSFRWAPEPRTVEnrlir....pqderlFKGKFDRLARVRALPEGVQILRACPVNVP-.......TKPEGRVISLKMYE..QPFTITEA...RRREVRQRLGVrEDGEKLVMFAKASWALKAMYYrml.qsgGrAARLTYSYEDFLQELLIHYIAEVDAP--VTVVGVMPQGKGEVYR.QEQRRFVS..MPFLPMNEFTELVLSCDLFVTDNMPSSATTRAVFGRVPVIVLTNTLL.TGTQDGSpltfPEHLRLSE.EGAALIQKW....NSLLHGGIYPFTIYPNGWIDELRPLFQNNPYCTTLVQAEMYALSETAHCFAELLC.NR....KAREVLQARQQAYIEQVV.GLPPTYDLFETWIATM-k..................................
A0A495XSR6_9PSEU/22-419              ..LAAQLAGAGIRSHFVVDLFNEEQLKAAD.LP.HTLLDPS...MGPAVRDVVRGAVHDFRPDAIVLAD.....YLGHWMTfDVGYSVDPWFID-----EFDLPVIPIDLYDLENTTREVE...............VLGR--TVQVSDRILGMGRHLQPVPMSRPT.......AVPGRLGRPYRVTR..STEPLTAA...RRAEVRRSLGL.GERDRLLMVPTLPWQESMRLH.......-.AGPATRELAARVPELVVRYLRRLPADTHFLLTG---PVFAGVEG.LPPDRVHL..RPAYGAREYDELVGTSDAVWSFHLPSFALERAVFADVPGMLSVNGFD.VAGPADA....DRLAEAFG.GLSPTVARW....LADYPGAVPSFHMWPLRWNSVLAPLMVDNPFGDAVERVELFDEAAVVGGLHDLLH.DP....GTRDRLAAARARYRDLID.ALPPTPEVFLAATRE--lg.................................
A0A5M6CIC3_9BACT/173-388             aq----------------------------.--.-------...-------------------------.....-------.---------------------------------------...............------------------------------.......--------------..--------...-----------.---------TMLKWKSKPGAKtifyplsKdRFNSIEVLYPDYFKYLATIFNELAAD-NVQIVTILPRKIQE--W.QSLSNVTI..LPAMSYSEFLSMISYSDLYLTDSYISC-IVDAIQLETPALLLMNSEE.T-----L....P------S.SE---I---....-SFLKGKVFPFWVWPYGMRRVCMQLERLFELKECYEKVEILNRNAVLHSIRDLLF.NE....QKQSELIGSCSKWKNKRKeMLPAPKSVIKNIMD---nh.................................
W4V273_9FIRM/24-415                  ..FASRLPNDIYDTYFLIPEKNKSFLDDRG.IK.NKTLSIW..eDPQINKKNIDKFINEVNPDFFIISDvytmeYAQSWTG.----------LNFAALKEYRIPIICIDEYEYTNAGYTVD...............YYGSIIR-NLPPLIEQGDYILCNCPFNKKR.......EESESRIKYFSLYG..EKLMLDES...KKKQVRERFKV.EDDEKIIFTAGSRWEMLNVHR.......-.-LPALGMFLKWMPVILQNYISALNRKITVIHVS---PTPWNEFE.SDLVRYHH..FNYLPPSEFDLYLLASDLFVTLNVVSVTLSKAVYGAVPSVVFQNHKI.IDFNKLS....NRLSQMPH.WYREMAQEL....-----KIAYPFRAGVFGWHRLLKTALEDNPYTQTYIEAPFFKVSEAISALEKYLY.DQ....TAIEELKQRQLEYVDKML.ELPTPDEVMRSIMS---dt.................................
A0A1Q4Y5P9_9PSEU/22-419              ..LMTQLEAAGVRCHFVIDAFNEDQLKAAG.FP.YTLVDPV...MGAAVRTVVEDVAREFRPDAVVLAD.....YVGHWMTlEVTYGCDPWFID-----GLGLPLIPMDLYDLANTSRTVE...............ILGK--STQVSDRLLDLPCHLQPVPMNRPQ.......VTGDGPGKPYRATL..AVEPPTAE...HRRAVRRSLGL.REGDRLLMVPTLPWQQLMARH.......-.AGGPAKVLASRLPGLVTHYLRQLPGQTHFVFTG---PVFEDVGG.LPPDRVHL..FSHYTVAEYDDLLGASDAVMSFHVPSFAIERAVFVDVPGVVCLNGFD.VAGPEDL....ARLDAEFG.GLTPTVAAW....LRTNPAPVPAFHMWPLSWNGLLGPMLADNPFTEVLHRAEIFDERSVLDRLDRVLY.DT....RTALELAEARARYRGLID.DLPPTPEVFDSVARRL-g..................................
A0A6B2V197_9ACTN/22-421              ..LAEQLADAGVESHFVVNPYNEEQLRAAR.LP.HTLVEPE...LGADVRQVVHRVVKEFRADAVVLVD.....YLAHWMTfKVGYRTDPWFVE-----DLGLPVIPLDLYDLENTSRRVE...............ILGT--TMEVDDNLTRMPVQLLPVPMNRPQ.......VTASGRGLPYRANR..TLAPLTAA...ARRETRACLGL.PGGARLLMVPTLPWQQLMQVH.......-.AAPPTRELAARLPRLLAGYLGRLPRDTHFLMTG---PLFEGFAElLPADRVHH..RPACTAAEYHRLLAAGDAVFAFHLPGYALERAVLADVPGLLAVNNHP.VDGPRDA....DRLGGAFAgGTTDRVRDW....LADYPGPLPDFHMWPLRWNEVLRPLLEANPFTETLLRAEILDENALVAGLERVLY.DE....AERDRLAAARAAYRDAVH.ALPDTAHTFTEAAHRL-g..................................
A0A3P3W435_9MICO/24-426              ..LAKRL-PEGWRAEVLVSAKHLDYAQAAG.VA.TRVLP--...RGRAAAAAVREAVSDAEVSGILLAD.....-------.HHLLGLERVGFGYDDLASRTAPLVAFDSLAFGVGPTRLKlavsr....gsedpmLRRWFPPEVDLDRVPDGVPLLRPVPVAAPIse..tleTSRTARIRSLDLYG..ESGPWGDAavtEPERIRSRLGV.EPHRKLVVVAMSNWASMAMTKpg...lgG.PNRERDAYLQLRFTWLHELMRRLDEP--IALVGVSAEGFDA---.-EGADVQTiaTGFLPLAEFTELLAAADLYLTDNLTSGAMARAVLLGTPAVTLTR---.-------....---EAEWH.TEDAFVTAWlaqmRAGFPASDFDYLVNPFGWIDELQPLLANNAYLAALPRIHAHDLDGQVRACRTALD.ST....---AQLA--RAALNAARG.ALPSGSEALLAALDAA-s..................................
A0A4R2JSX0_9PSEU/22-419              ..LAEQLKPMGFEHHFVILPGMEGMFRTAG.HP.CTVLRPE...MGPAVRDVIHEAVVTHRPDAFVLTD.....YFTFWVVlEKNFGIDPWFVK-----DYGVPLLPVDTWEWRQTDFAMD...............MTPE-DIRPVSKEIIGMPAHLRPVPLTRPR.......ADHEAGEFPFRLRV..GADRPSAA...GRRAVRDELGI.RGGDRLLFLPASAWQQRPVRN.......-.KDPRVLTIAAEVPNLVTHYLRQLPESTRFLVVGDVPP---ALRS.LPPDRTHI..LPVCPPERYSQLLCASDAVLAMTFQAVTLIRAMYAGIPGMVLTNKYT.IAGTRDA....EQAGAEFG.GLTPAVRQW....LAKV-GDIYRFRLWPLSMYSLMEPVLQDNPYLAAVAHSELLDERGVVDGLAGLLN.DR....AARDRLAEGRAGYLAEVD.SLADTPEVVSAALRMA-s..................................
#=GC seq_cons                        ..hAppLtttGhcscFllsstppshlcttG.hs.hplls.t...hsths+thlpphlpphpPDhllLuD.....ahth.hs..h.hthp..hls.....phslPlhslD.a-at.sshpl-...............hhGh..ph.ssspl.chshhLpPsPlspPp.......ssspstthsYplhp..ph..hott...c+pplRpcLGl.ptpc+llhlstusWpphhhpp..........hstspphschlspllspYLpcLspshpllhVG...s...shtt...ss+l+h..hshhssscac-LLsuuDlalohslsSsslsRAlhuslPulllhNsh..lsssttt.....thttt.t.thp.hlcph.......h.sslaPFphaPhGWhphLcPlhpsNPYhpsl.csElF-hctslcslcclLa.-p....ttpscLtpppstYhstlp.tLPss.Elhpthhp...s..................................
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