GenomeNet

Database: Pfam
Entry: DUF6426
LinkDB: DUF6426
Original site: DUF6426 
#=GF ID   DUF6426
#=GF AC   PF19990.2
#=GF DE   Family of unknown function (DUF6426)
#=GF AU   Williams LS;0000-0001-5551-8526
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Fragoso S;0000-0001-7018-3891
#=GF SE   Manual
#=GF GA   25.00 25.00;
#=GF TC   25.40 25.40;
#=GF NC   24.60 24.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   27191535
#=GF RT   A Single Gene Cluster for Chalcomycins and Aldgamycins: Genetic
#=GF RT   Basis for Bifurcation of Their Biosynthesis.
#=GF RA   Tang XL, Dai P, Gao H, Wang CX, Chen GD, Hong K, Hu D, Yao XS;
#=GF RL   Chembiochem. 2016;17:1241-1249.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a member of a biosynthetic gene cluster
#=GF CC   (BGC). This BGC (BGC0001396) is described by MIBiG as an example
#=GF CC   of the following biosynthetic class, polyketide, in particular
#=GF CC   the  aldgamycin J biosynthetic gene cluster from Streptomyces
#=GF CC   sp. A1(2016) [1].
#=GF SQ   8
#=GS A0A0N0MVU0_9ACTN/31-241   AC A0A0N0MVU0.1
#=GS A0A0M8Y516_9ACTN/39-252   AC A0A0M8Y516.1
#=GS B4VEK4_9ACTN/3-72         AC B4VEK4.1
#=GS A0A2H5BAX3_9ACTN/33-228   AC A0A2H5BAX3.1
#=GS A0A6B2XVN8_9ACTN/40-262   AC A0A6B2XVN8.1
#=GS A0A2H5AUT3_9ACTN/35-233   AC A0A2H5AUT3.1
#=GS A0A160FDI6_9BACI/123-241  AC A0A160FDI6.1
#=GS A0A2N0G3J2_9ACTN/34-235   AC A0A2N0G3J2.1
A0A0N0MVU0_9ACTN/31-241              ......................aC--DDSQSDCSDD----DSGGD..SGDSGDSG......DSGGSGGTDSgvedigstdtTIDASTGYVGETV-..LPEITVVGTAdPLPAVPADPLI----........ASG..GGGGGGDGAVVYNQ...GQTWEDRQNCYRNDSS.VTQKVTQSISYTVSTQVSTNISASALDVLTAAVGTQLNTTDTKTYTMEVTLAPGETWGLFVQ..YQTNVYAITTHDIFG.NYSTQFVNVTGPTGVATGRSC...
A0A0M8Y516_9ACTN/39-252              .......................CDHEDEEDPWPDDNPGGFPGGDpgDGGWGGGG......DGGGTGGSWG..........DIDMFNGVVGQPVDgtLPRVVVDGTA.TRPPTPMDPAMPPMS........WGW..GSGAPASGAGPIQA...GAKFERPTDCHRNADS.MPVRVNRTVKYQWSYETSANISANAAQVLSATLGAQVNTVFEESYSVDVTLQLGQSWTLFVE..YQTFTYSVTSSNIFG.YVTTEYVNVVRPTGKVTSRWC...
B4VEK4_9ACTN/3-72                    atghrtaalataraaeageraaq----------------------..--------......----------..........--------------..----------.---------------........---..--------------...----------------.---------------------------------------------------APGESWAVYVE..YQTNVYAITTSDFWG.NYSTEFVNVTQPTGVVAGRAC...
A0A2H5BAX3_9ACTN/33-228              .....................vh---CNSTICGPDEEPVFDDTGD..--------......DSQGGGG---..........---LTEEAPAEEVP..IPTVVITGQR.--PANPLAPVFPPYV........SGG..KNTVPHAGSFEVEAvtwSPRFDKHGPCFGNDVPgAVAKKFGGTSYQVSYEANAGISVDAASIISGTLGIKVNQTVTVTDNLEVTLQAGQEYAVYVT..YQTVTYKVTHHYLFS.D-SVEYVTITMPTKDTHIGAC...
A0A6B2XVN8_9ACTN/40-262              .......cgdedppinedpelpd----------PDNPSDPDNPGD..PDNPGDQGpvdaqlPTVVTNG--T..........NISLAPVEVGPDLD..VPTLNLVENA.TMPAAPEDPSIPSYS........WGSdaGGGGGQEMAIEHSQ...GKKWEEHTNCYRNASS.VAEKHTETISYNVTYQVSGNISAKAGDILSATLGTQINTQITKSYGLDVTLQPGESWSLFVE..YQTKVYAITTFDWLSlTYKTEFVNVTAPTGVLTGRSC...
A0A2H5AUT3_9ACTN/35-233              .......................CLDDGSDDSCIPP----DPGGS..GGGTGGTG......GSTGTGS---..........-LDVSDGNVGDPVP.dMPRVVITGVRvPEPFAPASPNIPSYW........---..--NGAAPGAGTYSA...GKTWDIPQNCYINHST.AVAKMTETITYAVTYQVSTNISATAAEVLTATLGTQLNSSITKTYTMEITLNPGQSWRLNVQ..YQTVVYAITTKNAFG.QLNTEYVNVTKPTGVLTGSAC...
A0A160FDI6_9BACI/123-241             .......ylknissgeacgtkii----------------------..--------......----------..........--------------..----------.---------------........---..--------------...------RQSTFAGPAT.ATLSVKEGVNASWS--SNTNVSA---EVVSTGLGFNVTKSYEVSDTYQIKVPSGKTYTIVARpyYQTYNFDVWYDPIIGsDYKAGYGNAFKPIGV------cfy
A0A2N0G3J2_9ACTN/34-235              ....................cwg---EYYSDCQWDPGAGYDPGGS..GGGDYGGG......DYGGGGG---..........---------GEV--..---VIIPGSKeSEPAEPAYPGDPSYSyesdssgaSGG..GSSGGADSAVPFRE...GEKAKLRLPCKRNDGP.APMKWNESSKYTVSYKVSGNISATAAKLLTVSVGGELNSTTEKSIGFEITLNPGQGFALDVE..YQTKEYMITTTNWLG.QTTVEFANVTAPTGAITAVPC...
#=GC seq_cons                        ......................t...p..p.s..Ds....DssGs..sss.hstG......sssGsGG................h....sGpsl...hPplslsGst.s.PssPhsPshPsh..........u...tssustsuAh.hpt...Gtpa-.+psCatNsuo.sshKhscolsYsVSYpsSsNISAsAuclLouoLGsplNoohpcohsh-lTLsPGpoWuLaVc..YQThsYuITTpshaG.shoTEaVNVTtPTGVlTupuC...
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