#=GF ID   DUF7558
#=GF AC   PF24439.1
#=GF DE   Family of unknown function (DUF7558)
#=GF AU   Pfeiffer F;0000-0003-4691-3246
#=GF AU   Andreeva A;0000-0002-0450-0091
#=GF SE   Friedhelm Pfeiffer
#=GF GA   27.00 27.00;
#=GF TC   29.60 72.70;
#=GF NC   26.70 25.90;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 8 -Z 81514348 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a small family of uncharacterised proteins
#=GF CC   found in archaea. They contain four pairs of conserved cysteines
#=GF CC   as well as several conserved histidines. It is likely that these
#=GF CC   residues are involved in metal coordination.
#=GF SQ   49
#=GS A0A1H6JRG9_9EURY/131-237  AC A0A1H6JRG9.1
#=GS A0A365T5R7_9EURY/2-108    AC A0A365T5R7.1
#=GS A0A4V6E8A5_9EURY/2-108    AC A0A4V6E8A5.1
#=GS A0A830G3J9_9EURY/13-73    AC A0A830G3J9.1
#=GS M0BZ56_9EURY/2-108        AC M0BZ56.1
#=GS A0A9E7NF87_9EURY/2-108    AC A0A9E7NF87.1
#=GS A0A1H4AAT9_9EURY/2-108    AC A0A1H4AAT9.1
#=GS A0A8J8P9U6_9EURY/2-108    AC A0A8J8P9U6.1
#=GS E4NVM8_HALBP/1-105        AC E4NVM8.1
#=GS A0A4U7F2I0_9EURY/2-108    AC A0A4U7F2I0.1
#=GS A0A1H3ZW63_9EURY/3-109    AC A0A1H3ZW63.1
#=GS Q5V7D1_HALMA/2-108        AC Q5V7D1.1
#=GS A0A1H6CC36_9EURY/3-109    AC A0A1H6CC36.1
#=GS Q9HHG0_HALSA/2-108        AC Q9HHG0.1
#=GS F8DEI3_HALXS/2-108        AC F8DEI3.1
#=GS A0A1G8ZBT2_9EURY/2-108    AC A0A1G8ZBT2.1
#=GS A0A6G2FWG5_9EURY/2-108    AC A0A6G2FWG5.1
#=GS A0A0P7GLA0_9EURY/2-79     AC A0A0P7GLA0.1
#=GS B9LVJ3_HALLT/2-108        AC B9LVJ3.1
#=GS M0FQG7_9EURY/2-108        AC M0FQG7.1
#=GS Q18KW3_HALWD/2-72         AC Q18KW3.1
#=GS A0A830F838_9EURY/2-107    AC A0A830F838.1
#=GS A0A1S8ART0_9EURY/2-108    AC A0A1S8ART0.1
#=GS A0A0F7PDC4_9EURY/2-108    AC A0A0F7PDC4.1
#=GS A0A1H3KN43_9EURY/2-108    AC A0A1H3KN43.1
#=GS A0A7D5CXH7_9EURY/2-108    AC A0A7D5CXH7.1
#=GS A0A0P7HQL2_9EURY/2-79     AC A0A0P7HQL2.1
#=GS A0A1I2WAF1_9EURY/2-108    AC A0A1I2WAF1.1
#=GS Q18KW3_HALWD/78-124       AC Q18KW3.1
#=GS M0C1C7_9EURY/2-108        AC M0C1C7.1
#=GS A0A6B9F257_9EURY/2-107    AC A0A6B9F257.1
#=GS A0A2B7GQ35_9EURY/2-108    AC A0A2B7GQ35.1
#=GS A0A1G9YCB9_9EURY/2-108    AC A0A1G9YCB9.1
#=GS A0A554MV51_9EURY/2-108    AC A0A554MV51.1
#=GS A0A2B7GQ48_9EURY/3-109    AC A0A2B7GQ48.1
#=GS M0C1U0_9EURY/3-109        AC M0C1U0.1
#=GS Q18IB4_HALWD/2-108        AC Q18IB4.1
#=GS A0A6B9F005_9EURY/3-109    AC A0A6B9F005.1
#=GS A0A1G9YJY4_9EURY/2-108    AC A0A1G9YJY4.1
#=GS A0A1H3HDM4_9EURY/2-108    AC A0A1H3HDM4.1
#=GS A0A0U5H867_9EURY/2-108    AC A0A0U5H867.1
#=GS M0L704_HALLS/2-108        AC M0L704.1
#=GS A0A2I8VRH1_9EURY/2-80     AC A0A2I8VRH1.1
#=GS A0A830FAQ3_9EURY/2-108    AC A0A830FAQ3.1
#=GS A0A8J8TBC9_9EURY/2-108    AC A0A8J8TBC9.1
#=GS A0A1H3KNT3_9EURY/2-63     AC A0A1H3KNT3.1
#=GS A0A7D5CF06_9EURY/2-108    AC A0A7D5CF06.1
#=GS Q18I81_HALWD/9-115        AC Q18I81.1
#=GS A0A7D5CIR0_9EURY/2-108    AC A0A7D5CIR0.1
A0A1H6JRG9_9EURY/131-237             ..gy--TLSGCAFCDAPPGTKIGEAHTWGEDERVTHPICVDCAIQTEPDPDERDHYACDSCGLVVDALAALTRFRVELGHLEGPLQLCERCSPGGLATYWTHDLKEHLVA-m.............
A0A365T5R7_9EURY/2-108               ....QQTLSGCAFCDVLPGLETGDAQTGGADERVTHTICVDCAIQTRPDPDERGHHACDSCGLVVDTLAALTRFRVDLGHLEGPLQFCARCSPCGPATYWTRTLEKHLA--av............
A0A4V6E8A5_9EURY/2-108               ....QQTLVGCAFCDAPPGTETGEAHTWGQDERVTHPICVDCAIQTEPDSDERDHVACDGCGLVVDTLAALTRFRVELGHLEGPLQLCARCSPGGLATYWTRDLEEHLVA-t.............
A0A830G3J9_9EURY/13-73               ..cr--ELNGCAFCDAPPGTEAGEAHTGGQDERVTYPICVDCAIQTEPDPIS-----------------------------------------------------------aitttvtavdwss.
M0BZ56_9EURY/2-108                   ....QQTLAGCAFCDALPGTEAGEAHTWGKDKRVSHPICVDCAIQTEPDPDEFDHCTCDGCGLIVDALAALTRFRVELGHLEGALQLCARCSTGGPATYWTRDLEEHIVK-t.............
A0A9E7NF87_9EURY/2-108               ....QQTLSGCAFCEAVPGSAAGTAYTWGKDERVTHPICVDCAVQEHPDPSERDHHACDSCGLVVDTLTALTRFRVELGHLEGSLQLCAHCSPTGPATYWTRDLETHVVDE..............
A0A1H4AAT9_9EURY/2-108               ....QQTLSGCAFCDSPPGAEMGEAHTWGKDERVTHPICVDCATQTRSDPDERDHHACDGCGLVVDALAALTRFRVELGHLEGPLQLCARCSPGGLATYWTRDLTEHLVAE..............
A0A8J8P9U6_9EURY/2-108               ....QQTLAGCAFCEAPPGSETGIAYTWGKEERVSHPICVDCAIQERPDPDERDHYACDSCGLVVDALAALTQFRIELGHLEGPIQVCARCSPGGPATYWTRDLDPHIVS-d.............
E4NVM8_HALBP/1-105                   ...m---LTGCASCDAPPGTETGKAHTWWQDERVTHPICVDCAIQREPNPDERDHVACDGCGLVVDTLAALTRFRVELGHLEGPLQLCARCSPGGLATYWTRDLEEHLVA-t.............
A0A4U7F2I0_9EURY/2-108               ....QQTLAGCAFCEAPPGTETGIAYTWGKEERVSHPICVNCAIQETPDPDKRNHYACDSCGLVVDALAALTRFRIELGHLEGPIQVCARCSPGGLATYWTRDLDTHIVS-d.............
A0A1H3ZW63_9EURY/3-109               ....QQTLAGCAFCEAPPGTETGIAYTWGKEEQVSHPICVDCAIQETANPDERDHYACDSCGLVVDALAALTRFRIELGHLEGPIQVCARCSPGGPATYWTRDLDTHIVS-d.............
Q5V7D1_HALMA/2-108                   ....QQTLAGCAFCEAPSGIETGIAYTWGKEERVNHPICVDCAIQETPDPDDRDHYACDSCGLVVNALAALTRFRIELGHLEGPIQVCARCSPGGPATYWTRDLEAHIVS-d.............
A0A1H6CC36_9EURY/3-109               ....QQTLVGCAFCAAPPGTDTGTAYTWGKDERVSHPICVDCATQVTPDPEQRDHYACDGCGLVVDALAALTRFRVELGHLEGPLQFCAHCCPDGPATYWTRDLADHCVE-s.............
Q9HHG0_HALSA/2-108                   ....QQTLVGCAFCDAPPGTETGEAHTWGQDERVTHPICVDCAIQERPDSNDLDHHAYDGCGRIVDTLPALTSFHVELGHLDGTVHLCVRCSPGGPATYWTRDLEEHLVA-d.............
F8DEI3_HALXS/2-108                   ....QQTLVGCAFCDAPPGTETGEAHTWGQDKRVTHPICVDCAIQTEPDPDERDHVACDSCGLVVDTLAALTRFRVEVGHLEGPLQLCARCNPGGLATYWTRDLEDHLVA-t.............
A0A1G8ZBT2_9EURY/2-108               ....QQTLVGCAFCDAPPGTETGEAHTRGQDERVSHPICVDCAIQMEPNPDERDHVACDGCGLVVDTLTALTRFRVELGHLEGPLQLCALCSPGGLATYWTRTLEEHLVA-t.............
A0A6G2FWG5_9EURY/2-108               ....QQTLTGCAFCDAPPGTETGEAHTWGQDERVTHPICVDCAIQTEPDPDERDHVACDGCGLVVDTLAALTRFRVELGHLEGPIQLCARCSPGGLATYWTRDLEEHLVA-t.............
A0A0P7GLA0_9EURY/2-79                ....QQTLVGCAFCDAPPGAETGEAHTWGQDERVTHPICVDCAIQTEPDPDERNHVACDSCGLVVDTLAASPAH-------------------------------------ragfqrdl......
B9LVJ3_HALLT/2-108                   ....QQTLTGCAFCDAPPGTESGEAHTWGEDERVTHPICVDCAIQTELDPDERNHYACDGCGLVVDALAALTRFRVELGHLEGPLQLCERCSPGGLATYWTRDLEEHLVA-d.............
M0FQG7_9EURY/2-108                   ....QQTLVGCAFCDAPSGTEPGEAHTWGQDERVTHPICVDCAIQTEPDPDERDHVACDGCGLVVDTLAALTRFRVELGHLEGPIQLCARCNPGGLATYWTRDLEEHLVEQ..............
Q18KW3_HALWD/2-72                    ....QQTLSGCAFCDSPPGSEMGEAHSWGKDERVTPPICVDCAVQERPDPEERDHHTCDGCGLVVDALAA-----------------------------------------spalp.........
A0A830F838_9EURY/2-107               ....QQTLTGCAFCDAPPSTETGEAHTWGEDERVTHPICVDCAIQMEPDPNERDRYACDGCGLVVDALAALTRFRVELGHLEGPLQLCARCSPGGPATYWTHDLDEHLVE-..............
A0A1S8ART0_9EURY/2-108               ....QQTLIGCAFCDALPGTETGEAHTWGQDERVTHPICVDYAIQTEPDPDECDHVACDGCGLAVDTLAALTRFRVELGHLEGPLQLCARCSPGGLATYWTRDLEEHLVA-t.............
A0A0F7PDC4_9EURY/2-108               ....QQTLTGCAFCDAPPGAETGEAHTWGQDERVTHPVCVDCAIQVEPDPDERDHFACDGCGLVVDALAALTRFRVELGHLEGPLQLCEHCSPGGLATYWTRDLKEHLVA-t.............
A0A1H3KN43_9EURY/2-108               ....QQTLSGCAFCDAPPGAEMGEAHTWGKDERVTHPICVDCATQTWSDPDERDHHACDGCGLVVDALTALTRFRVELGHLEGPLQLCARCSSGGPATHWTRDLEEHLVS-y.............
A0A7D5CXH7_9EURY/2-108               ....QQTLSGCGFCDSPPGAEMGEAHTWGQNERVTHPICVDCAVQERPDPVERDHHACDGCGLVVNALAALTRFRVELGHLEGPLQLCARCSPGGLATYWTRDLTEHLVAE..............
A0A0P7HQL2_9EURY/2-79                ....QQTLVGCAFCDAAPGTETGEVHTWGQDERVTHPICVDCAIQTEPDPDERNHVACDGCGLVVDTLAASPAH-------------------------------------ragfqrdl......
A0A1I2WAF1_9EURY/2-108               ....QQTLSGCAFCETLPGSEMGEAHTWGQDERVTHPICVDCAVQEQPDPEEHDHYACDGCGLVVDTLAALTRFRVELGHLEGPLQLCEHCSPGGLATYWTRDLEEHLVAE..............
Q18KW3_HALWD/78-124                  tfgp----------------------------------------------------------------AQLTRFRVELGHLEGPLQFCERCNPGGLATYWTRDLEEHLVQE..............
M0C1C7_9EURY/2-108                   ....QQTLAGCAFCDALPGTEAGEAHTWGKDERVSHLICVDCAIQTEPDPDEFDHCTCDGCGLVVDTIAALTRFHVELGHLEGSLQLCARCSPGGPATYWTRDLEKHIVS-d.............
A0A6B9F257_9EURY/2-107               ....QQTLTGCAFCDAPPSTETGEAHTWGEDERVTHPICVDCAIQMDPDPDERDRYACDGCGLVVDALAALTRFRVELGHLEGPLQLCARCSPGGPATYWTHDLDDHLVE-..............
A0A2B7GQ35_9EURY/2-108               ....QQTLVGCAFCDAPPGTEAGEAHTWGKEERITHPICVDCAIQTRPDPDERDHHTCDGCGLVVDALAALTRFRVELGHLEGPLQICARCSPGGPATYWTRDLEEHLVA-t.............
A0A1G9YCB9_9EURY/2-108               ....QQTLVGCAFCDAPPGTETGEAHTWGTNERVTHPICVDCAIQTESDPNHCDHHACDGCGLVVDALAALTRFRVELGHLEGPLQLCEQCSPGGLATYWTRDLEEHLVSE..............
A0A554MV51_9EURY/2-108               ....QQTLVGCAFCDAPPGTETGEAHTWGEDERVTHPICVDCAIQTEPDPDVRDHVACDGCGLVVDTLAALTRFRVELGHLEGPLQLCARCSPGGLATYWTRDLEEHLVA-t.............
A0A2B7GQ48_9EURY/3-109               ....QQTLAGCSFCEASPGTETGTAYTWVKDERVSHLICVDCAIQSRPDPDKHDHSAYDGCGLIVNTLAALTRFRVQLGHLEGTIQLCARCSPGGPAMYWTRNLEEHVVA-v.............
M0C1U0_9EURY/3-109                   ....QQTLAGCSFCEGPPGTETGTAYTWGKDERVSHLICVDCAIQIRPDPDKSDHHACDGCGLVVDALAALTRFRVELGNLEGSLQLCARCSPGGPATYWTRDLEEHLIDQ..............
Q18IB4_HALWD/2-108                   ....QQTLSGCAFCDSPPGSQMGEAHTWGKDERVTHPICVDCAVQERPDPEERDHHTCDGCGLVVDALAALTRFRVELGHLEGPLQFCARCNPGGLATYWTRDLEEHLVQE..............
A0A6B9F005_9EURY/3-109               ....QQTVVGCAFCAAPPGTDTGTAYTWGKDERVSHPICVDCATQVTPDPEQRDHYACDGCGLVVDALAALTRFRVDLGHLEGPLQFCADCCPDGAATYWTRDLADHRVE-s.............
A0A1G9YJY4_9EURY/2-108               ....QQTLAGCAFCDAVPGTDVGEAHTWGKDERVTHPICVDCAIQSNPDPDERDHHACDSCGLVVDALAALTRFRVELGHLEGPLQLCARCSPDGPATYWTRDLGDHLVSE..............
A0A1H3HDM4_9EURY/2-108               ....QQTLVGCAFCDAPPGTETGEAHTWGQDERVTHPICVDCAIQTEPDPDECDHVACDGCGLVVDTLAALTRFRVELGHLEGPLQLCARCSPGGLATYWTRDLEGHLVA-t.............
A0A0U5H867_9EURY/2-108               ....QQTLVGCAFCDAPPGTETGEAHTWGQDERVTHPICVDCAIQTEPDPDERDHVACDGCGLVVDTLAALTRFRVELGHLEGPVQLCARCSPGGLATYWTRELEEHLVA-t.............
M0L704_HALLS/2-108                   ....QQTLTGCAFCDAPPGTETGEAHTWGQDERVTHPICVDCAIQTEPDPDGRDHVACDGCGLVVDTLAALTRFRVELGHLEGPLQLCARCSPGGLATYWTRDLEEHLVS-t.............
A0A2I8VRH1_9EURY/2-80                ....QRTLSGCAFCDALPGSEMGEAHTWGKDERVTHPICVDCAIQARPNPDERDHHACDGCGLVVDTLI------------------------------------------lqcgskpltvghna
A0A830FAQ3_9EURY/2-108               ....QQTLVGCAFCDAPPGTETGEAHTWGQDERVTHPICIDCAIQTEPDPDERDHVACDGCGLVVDTLAALTRFRVELGHLEGPLQLCARCSPGGLATYWTRDLEEHLVA-t.............
A0A8J8TBC9_9EURY/2-108               ....QQTLSGCAFCDSPPGAEMGEAHTWGKDERVTHPICVDCATQTQSDPDERDHHACDGCGLVVDALAALTRFRVELGHLEGPLQLCARCSPGGLATYWTRDLTEHLX--xx............
A0A1H3KNT3_9EURY/2-63                ....QQTLTGCAFCDAPPGTKTGEAHTWGEDERVTHPIRVDCTIQTEPDPDERDHYVCDSVG-------------------------------------------------ssst..........
A0A7D5CF06_9EURY/2-108               ....QQTLVGCAFCDAPPGTETGEAHTWRQDERVTHPICVDCAIQTEPDPDERDHVACDGCGLVVDTLAALTRFRVELGHLEGPIQLCARCSPGGLATYWTRDLEAHLVS-d.............
Q18I81_HALWD/9-115                   ...a-AALVGCAFCDAPPGTETGEAHTWGTDERVTHPICVDCAIQTESDPDKRNRYACDGCGVVVDTLAALTRFRVELGHLEGPLQLCERCSPDGLATYWTRDLEGHLVSE..............
A0A7D5CIR0_9EURY/2-108               ....QQTLVGCAFCDAPPGTETGEAHTWGQDERITHPICVDCAIQTEPDPDERDHVACDGCGLVVDTLAALTRFRVELGHLEGPLQLCARCSPGGLATYWTRDLEEHLVA-t.............
#=GC seq_cons                        ....QQTLsGCAFCDAPPGTETGEAHTWGpDERVTHPICVDCAIQscPDPDERDHhACDGCGLVVDsLAALTRFRVELGHLEGPLQLCARCSPGG.ATYWTRDLE-HLVu.s.............
//