#=GF ID   DUF8049
#=GF AC   PF26223.1
#=GF DE   Domain of unknown function (DUF8049)
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   UniProtKB:A0A384KZE9
#=GF GA   27.00 27.00;
#=GF TC   32.20 36.10;
#=GF NC   25.80 22.30;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 90746521 -E 1000 --cpu 8 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents a family of uncharacterised integral
#=GF CC   membrane proteins found in halobacteria. These proteins contain
#=GF CC   three predicted transmembrane helices.
#=GF SQ   37
#=GS A0A1H3WDK4_9EURY/1-86    AC A0A1H3WDK4.1
#=GS A0A8T4GBY8_9EURY/1-85    AC A0A8T4GBY8.1
#=GS B9LUS9_HALLT/1-85        AC B9LUS9.1
#=GS V4Y2S1_9ARCH/1-66        AC V4Y2S1.1
#=GS A0A1H5YVF6_9EURY/17-100  AC A0A1H5YVF6.1
#=GS F7XL85_METZD/1-81        AC F7XL85.1
#=GS A0A081EY03_9EURY/1-85    AC A0A081EY03.1
#=GS A0A2I8VJ65_9EURY/1-85    AC A0A2I8VJ65.1
#=GS A0A256H4B3_9EURY/1-85    AC A0A256H4B3.1
#=GS A0A1H6RGR2_9EURY/1-84    AC A0A1H6RGR2.1
#=GS D4GZ65_HALVD/6-88        AC D4GZ65.1
#=GS A0A238UR87_HALVU/1-85    AC A0A238UR87.1
#=GS V4XSX1_9ARCH/1-85        AC V4XSX1.1
#=GS M0DQV1_9EURY/1-85        AC M0DQV1.1
#=GS O27174_METTH/1-86        AC O27174.1
#=GS A0A1M5RKM6_9EURY/1-85    AC A0A1M5RKM6.1
#=GS E4NL01_HALBP/4-91        AC E4NL01.1
#=GS A0A7D5GGP6_9EURY/1-85    AC A0A7D5GGP6.1
#=GS A0A1I6IQG1_9EURY/3-89    AC A0A1I6IQG1.1
#=GS A0A4U7FCI4_9EURY/1-85    AC A0A4U7FCI4.1
#=GS A0A1H6IB27_9EURY/1-85    AC A0A1H6IB27.1
#=GS A0A3A6PMW3_9EURY/1-84    AC A0A3A6PMW3.1
#=GS A0A6G2FY28_9EURY/3-89    AC A0A6G2FY28.1
#=GS A0A4D7HC55_9EURY/1-82    AC A0A4D7HC55.1
#=GS A0A6A9T357_9EURY/1-85    AC A0A6A9T357.1
#=GS A0A343TKH9_9EURY/1-84    AC A0A343TKH9.1
#=GS A0A521E4G3_9EURY/1-85    AC A0A521E4G3.1
#=GS A0A6G2HEI1_9EURY/1-85    AC A0A6G2HEI1.1
#=GS A0A1I2UUA6_9EURY/5-91    AC A0A1I2UUA6.1
#=GS A0A7D5QGR0_9EURY/1-85    AC A0A7D5QGR0.1
#=GS A0A133UL64_9EURY/1-80    AC A0A133UL64.1
#=GS A0A498GBG1_9EURY/8-94    AC A0A498GBG1.1
#=GS A0A8J8P8C0_9EURY/1-84    AC A0A8J8P8C0.1
#=GS F4BWX6_METSG/1-85        AC F4BWX6.1
#=GS A0AAE3FXD5_9EURY/1-85    AC A0AAE3FXD5.1
#=GS A0A1G9WBU1_9EURY/1-90    AC A0A1G9WBU1.1
#=GS B8GH59_METPE/9-93        AC B8GH59.1
A0A1H3WDK4_9EURY/1-86               ........MNISaDVAA..DLRVAAVAAGCTVALSLVLRYG.LGIAASPLLRLSPIAVYFGYLFLGKG.STG.....sAFE...NPRLWMVLTAVVTVATGAYLA-t.
A0A8T4GBY8_9EURY/1-85               ........MGIE.RARG..DLLVAASAGGSTIVLAVVSSVI.GAVTIGTAPTLVPLGVYLAYLFSRKGgPYG......GMD...TSRNWAVAAVLAGFIVLAIE--ag
B9LUS9_HALLT/1-85                   ........MEIE.RARD..DLVVAASAGSATIVIALLSGVA.GVLNVSTLPTLAPLVVYAGYLFSRKGgPYG......SLD...RPRNWATAAVLVGVLVVAAAS-v.
V4Y2S1_9ARCH/1-66                   ........MDTD.SFRR..EVVVASAAAGATVALSLVFEFV.LAVTPSFYLQAAPLSVYFLYLFGH-GrLPD......RAD...QP--------------------ts
A0A1H5YVF6_9EURY/17-100             ...aeadl----.-PTD..DLRVAVVAAACTVGLTLLLQYG.LGREVALAWRLLPLAPYFLSLFTKRL.ELG......GLD...TPRNWSLLTVAVTLATFGYV--gf
F7XL85_METZD/1-81                   ......mk----.KLKN..EIKLALLTLGCIVIIAIFSKYY.LEEEMSFISRNAPLWMFLLYLFVS--.--D......KIQvsgMLRYYSAAIILISMIVIAIHMI..
A0A081EY03_9EURY/1-85               ........MEIE.RARD..DLVVAASAGATTITVALLSGVA.GVVDVPTLPTLAPLAIYAGYLFSRKGgPYG......SLD...RPRNWAAGAVLVGVIVVAASV-v.
A0A2I8VJ65_9EURY/1-85               ....melp---E.SVRD..DLLVALVAAGCTVALTVSLRFG.AGVQPPLLPRLSPLVPYFGYLFSK--.RSGp....lSTL...SPLDWIGATVVVTLLTFVYL--st
A0A256H4B3_9EURY/1-85               ........MEIE.RARD..DLVVAASAGATTVAVAVLSGVA.GVVEVGTLPTLAPIAVYAAYLFSRKGgPYG......PLD...EPRNWAVAAALVGVVVAVAAAV..
A0A1H6RGR2_9EURY/1-84               ........MDLE.DAWT..DTLVATGVAATTIVVTVLLVFV.FAVDTNPLLRLSPLGIYFVYLFTHRR.LPE......GVD...TPRNWIALTALVGIGVLLVAA-g.
D4GZ65_HALVD/6-88                   ...daatd----.QFRDltDVKVALVAGVCTVALTLSLEYG.AGIEVPFVYRLSPLAPYFAYVFSR--.--G......AAL...SARTWMALIAVVTLGTFGFFV-f.
A0A238UR87_HALVU/1-85               ........MKIE.RARE..DLVVAGSGAGATVVLAILSSVG.LVGEISSIAMLAPVFVYFAYLFSRKGgPYG......SWD...LARNWAILAILVALGVLVGS--lv
V4XSX1_9ARCH/1-85                   ........MTIE.RARE..DVAVAASACLASVAVAVSSSLV.SAVTVETLPALAPIVVYVAYRFSRKGgPYG......SID...TPRNWAALALVAGAVVLVVGA-w.
M0DQV1_9EURY/1-85                   ........MEIE.RARD..DLVVAASAGGATIAIALLSGVA.GVVDVPTLPTLAPLVVYAGYLFTRKGgPYG......APD...RPRNWAAAAVLVGVLVVVTT--sv
O27174_METTH/1-86                   .......m----.RLSD..QNKVSLVAGLCLVGLVIVLKNL.LLIPSDILSRDVLVYIIIYWAFTVIPgRRGek..gsKYD...HPLYWSLLIILITLVIITMYLI..
A0A1M5RKM6_9EURY/1-85               ........MDLS.DARE..DLLVAAAAALGAVGLTVVLDLL.AGVPVSTPVRVAPLAVYFAYLFTRKGgPYG......SFD...TPRNWTAFVVVVTVAAAGYAV-a.
E4NL01_HALBP/4-91                   .ndsaati----.PVSD..DLKIAAVAAGCTVAFTLVLRFGlAARNVSFLVRLLPLVPYFLYVFTRRI.DLG......SLD...TVRNWSVLTLLITIIGLGFYAI..
A0A7D5GGP6_9EURY/1-85               ........MALE.SVRD..DLLVAGVAAACAVTLTLSLELL.ANVSVSVWLHSTPLAVYFAYLFSRKGgPYG......PLD...TAQNWAVLAVAVTVVAGAYAL-f.
A0A1I6IQG1_9EURY/3-89               .ddstael----.PVPD..DLKLAAVAAACTVGLTLALEYG.LSRDVSFLVRLVPLVPYFVYLFSRPV.RSG......KLD...SVRNWSVLTVSVTLGVLVYAAV..
A0A4U7FCI4_9EURY/1-85               ........MEIE.RARD..DLVVAASAGAATIAVALLSGVV.GVVEVGTLPTLAPLAVYAVYLFSRKGgPYG......TLD...EPRNWGIAAVLAGVAVVAASA-a.
A0A1H6IB27_9EURY/1-85               ........MDLE.DARE..DVIVAAVAAVSTIAVAVVGRLV.PVTDPGTVPTLAPIGVYLLYLFTRKGgPYT......ALD...TVRNWGLLAVASAFAAIGYG--il
A0A3A6PMW3_9EURY/1-84               ........MDTE.SVRT..DLGVAAAAAGSTVALAIAFAVA.LPTEPDFYLQAAPLSVYFVYVFIHRK.LPD......SVD...QPAMWSGLAVAAAVGAFGLAV-l.
A0A6G2FY28_9EURY/3-89               .ddsaatl----.AVPD..DLKVAAVAAACTVGLTLVLRFV.LARDAPYVVRLLPLVPYFAAVFTRRL.DLG......AFD...TVRNWSALTLAVTLGTILYYAV..
A0A4D7HC55_9EURY/1-82               .......m----.DVPD..DLKVAAVASACTVGLSLSLRYG.LRVDANLFVRLLPLFVYFVYLFAKDAlSET......ALG...ETTTWYVVTVAATLAAAVFYAI..
A0A6A9T357_9EURY/1-85               ........MEIE.RARD..DVLVAAAAGGTTIAIALLSGVV.GVVEVATLPTLAPLAVYAAYLFSRKGgPYG......PLD...DPRNWAVTAVLAGVVVLAAAAV..
A0A343TKH9_9EURY/1-84               ........MDLE.QARE..DLLVAGVAAGCAIGLTLGFEYV.LAASIPLQYRLIPLLVYVVYVFSRKGgPYG......RYD...TPMAWAVLAVLVTVATAVVV--a.
A0A521E4G3_9EURY/1-85               ........MEIE.RARE..DVLVAAGAGLSTVAVAVLSSLV.SAVSVGTLPSLAPLSVYVAYLFTRKGgPYG......SID...AARNWAVLAVVVGIVVLALG--tf
A0A6G2HEI1_9EURY/1-85               ........MEIE.RARE..DVVVAGTAAAATVALAVVSGLG.LIGDIGALATLSPVLVYFAYLFSRKGgPYG......SWD...TARNWALLAALVGAVVLLTT--ll
A0A1I2UUA6_9EURY/5-91               .dseaatl----.DVPD..DAYVAAVAAVSTIALTLAFEYG.VGADPPFLSRLAPLGPYFLSVFARGV.DLG......PVD...TVRVWSLLTAAVTLSVFLFYAV..
A0A7D5QGR0_9EURY/1-85               ........MDLD.SVRE..DLLVAGVAAGGAVGLTLALELL.ADVSVPFWLEAAPLGVYFAYLFTRKGgPYG......PYD...TVRNWALLAAMVALAAAAYAL-l.
A0A133UL64_9EURY/1-80               .......m----.EISD..EVKVSLVTAVCVLALAIISKNI.LQVELDFITQYGPVWLFITYIITR-G.KEK......SSG...KPLIWSATIIIVTIAILFLYS-f.
A0A498GBG1_9EURY/8-94               tdlsnagl----.-ATD..DLRVAVVAAACTIGLTLGLRYG.LGREIAFVWRLLPLGPYFLSLFTKRL.QLG......GLD...TARNWSLLTVAVTLGAFVYFG-v.
A0A8J8P8C0_9EURY/1-84               ........MDTD.RFRQ..DVIVATAAAGSTVALSLIFEFG.LEIEPSFFLQAAPLGVYFLHVFGHSF.LPD......SVD...RPRYWVGLALAVAVVAFVIAT-l.
F4BWX6_METSG/1-85                   ........MARDmRLNN..QAKVGLATVVCLLLQGYIFTYV.LFVEPHPLVSILPLFPYLAYVYAR-GkRTW......YFN...KPLYWIGLVAMVTVLDILPFAV..
A0AAE3FXD5_9EURY/1-85               ........MDLD.SARD..DLVVAAAAGVSTVLLTVVLRFV.FDASTNALIQLSPLYVYFIYLFFGDAiPGE......LFS...KPLPWVGITLSTAIGAVALTV-f.
A0A1G9WBU1_9EURY/1-90               ...mdtdt-DTElAIPD..DLWVALVAAACTIGLSLVLRFG.LGQSTSVVVRLVPIAPYFVYLFVKKS.VEG.....sPLA...AVRTWAALIVVTTLAVLGYVA-l.
B8GH59_METPE/9-93                   ...rngrf----.----..--IVTLTAALCLILLAIVLKNV.LHVPATQLSSDMILYIILYTGFIVSF.QFTdnalpiSST...QTKIWTAVSILMTLGIIAVYAI..
#=GC seq_cons                       ........Mth-.ps+-..DlhVAusAuusTluLsllhphs.hslssshlspLuPLslYhsYLFoR+u.shG......uhD...psRsWuslsllVslsshshhs.h.
//