#=GF ID   DUF8093
#=GF AC   PF26362.1
#=GF DE   Domain of unknown function (DUF8093)
#=GF AU   Andreeva A;0000-0002-0450-0091
#=GF SE   Andreeva A
#=GF GA   27.00 27.00;
#=GF TC   31.60 33.10;
#=GF NC   26.60 25.00;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 90746521 -E 1000 --cpu 8 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found in a group of proteins from proteobacteria,
#=GF CC   including T6SS lipase effector (Tle) proteins. The function of
#=GF CC   this domain is unknown but in Tle, it precedes the lipase
#=GF CC   domain.
#=GF SQ   26
#=GS A0A5J5FW70_9GAMM/1-138   AC A0A5J5FW70.1
#=GS L0M6B2_ENTBF/6-153       AC L0M6B2.1
#=GS A0A379AL24_ENTAG/8-45    AC A0A379AL24.1
#=GS A0A484XRI9_9ENTR/6-77    AC A0A484XRI9.1
#=GS A0A090UVB3_PSEVU/4-140   AC A0A090UVB3.1
#=GS A0A384KL32_YERPE/8-148   AC A0A384KL32.1
#=GS A0A1W6B9Y5_9GAMM/8-76    AC A0A1W6B9Y5.1
#=GS A9MS34_SALAR/8-150       AC A9MS34.1
#=GS A0A240BJH2_SERFI/1-75    AC A0A240BJH2.1
#=GS A0A7Z8Z9A1_RAOTE/22-125  AC A0A7Z8Z9A1.1
#=GS A0A1W6B3J5_9GAMM/8-149   AC A0A1W6B3J5.1
#=GS A7MQ31_CROS8/4-138       AC A7MQ31.1
#=GS A0A0J5NHR8_PLUGE/5-141   AC A0A0J5NHR8.1
#=GS A0A1W6B416_9GAMM/8-149   AC A0A1W6B416.1
#=GS A0A0H3CIY9_ENTCC/4-138   AC A0A0H3CIY9.1
#=GS A0A6M8UGV8_9GAMM/8-148   AC A0A6M8UGV8.1
#=GS H5V5P2_ATLHE/8-150       AC H5V5P2.1
#=GS A0A240C997_SERFI/1-142   AC A0A240C997.1
#=GS A0A6M8U6R4_9GAMM/8-147   AC A0A6M8U6R4.1
#=GS A0A830ZER2_9ENTR/1-131   AC A0A830ZER2.1
#=GS A0A240B422_SERFI/1-142   AC A0A240B422.1
#=GS A0A1C3ZMD4_9ENTR/1-142   AC A0A1C3ZMD4.1
#=GS A0A2N5EI89_9GAMM/6-153   AC A0A2N5EI89.1
#=GS A0A2U2GYB9_YERPE/8-77    AC A0A2U2GYB9.1
#=GS Q0WJ32_YERPE/8-148       AC Q0WJ32.1
#=GS B2VHH3_ERWT9/13-154      AC B2VHH3.1
A0A5J5FW70_9GAMM/1-138              ...............MRLVDLRCEKLSLEKYDHILSPAHARRLLSQEFVLVHAPANN...FFPV......PGYQLR---SRTGFCSHNQPSADITPLL-KLIDTGEVVVVDE-H..GSWNRSLHPFFIAGDGHLVHAGVAD...SAHFFGSTVLQHYQNELSM.....CSAK.PRPTQ....................
L0M6B2_ENTBF/6-153                  .......elndlnyy----------LLPEDYPFILNPDDALREAEKYYDME-PCNQMlggMTII......PARKFTQTFYHTPNDYNSLHHNPVYENIKRGLEIGTIIGIDVMRlgRRWSSYCNLFYVDVFGDLTLNARPTl.cYSPTSIEWIIRSYNECRRR....hNIKR.PRPT-e...................
A0A379AL24_ENTAG/8-45               ..............n-RLICLSGNNLSPESFERIISPFAAWRHAGQDYQFDD-----...----......--------------------------------------------..-------------------------...-------------------.....----.-----r...................
A0A484XRI9_9ENTR/6-77               ...........iihs------------------------------------------...----......-----------------------------HNIDIGWFIGIDE-C..EQWDYFKHPFYFDEKGDLIYDCFMS..hWHEWFEMEVRDAYRKCLDS.....HQGK.ETST-n...................
A0A090UVB3_PSEVU/4-140              ...............IKFIYLYSEKVRPAMFDKIMRP-----SVAGQWIMSVPENSL...RSLF......TRYDLL---QSISGANPNQPGRNTRKIIVRDLDFGRLVAIDDST..RGWSAATEMFYINGEGELTLAPSGKeglSWSYSVSTVIERYETMVRT.....YGR-.PPAT-v...................
A0A384KL32_YERPE/8-148              ...............MYLYYLSRDNLAPEEYERIISPHAAWARICREYEFDDSHNTR...RYLI......---NMREREQRSSPDQPRPGGIREKEKLEKLVFSGDVVMLSDLY..G----PARLFYINGEGQLMSADPHA...FRFEGAAKIIKAFDDSVKCrnyqrTGGK.PRPT-k...................
A0A1W6B9Y5_9GAMM/8-76               ..............t-DLYYLQHDNLAPERYEEIISPFLAWSRIVSEYVFDDRRPLD...FRLI......---NMQ--------------------------------------..-------------------------...-------------------.....----.-----krnvygyshttpphgprerv
A9MS34_SALAR/8-150                  ...........hdlt--------RQLDPEDFQYILTPAGSLKEACIHYDLSYEANGH...SLTFgl..pkEKYSISPH-QRPYERRHRSYADPIYDEVEHELQIGWLVGVDT-S..RHWSSDRNPFYIDDNGDLIFTPTAS..sWHAWYKDEITSAYRHAIAD....rQGRK.PAPTQ....................
A0A240BJH2_SERFI/1-75               ...............------------------------------------------...----......-----------------------MKRAVFDDINQGSLLAIGNSF..GAWSSAKHVFYIDADGKLQRYPGSH..lPALYPVAHVIERYEDMVHR.....YGQR.PKPTV....................
A0A7Z8Z9A1_RAOTE/22-125             rsvpkrrggvyhrfa------------------------------------------...----......---------AQPYKRKRLTEYDGLYDEVKWNLDHGWMVGVNT-K..EKWEHFRNPFYFDDDSNLIYDCFMD..tYSEGFQQAVRQIYEYSLNE....hQGRK.PPPT-i...................
A0A1W6B3J5_9GAMM/8-149              ..............n-RLICLSRDTLAPESFERIISPLAAWRHIEQDYRFDDRWNNS...LYIV......---NIFPKSAHPLAATLPEYGRRSKEQLKALTERGEVVCLNDVS..VL---PAGLFYIDDNGMLICRDRTL...FRFDGANSIIAAFNLAVSKrdyrySGGK.PTPTS....................
A7MQ31_CROS8/4-138                  ...............IKIVSIFKEFIPPAQFERIMRP-----DIAAQWIMSVPDNAV...RSLF......TRYELF---QPSTRANPYQSGRDLRKLIADEFWHGNLVAIDESS..RPWSPTTELYYINEKGELEPTHAPR...SLMFPLGYIIVRYGSMVRV.....YRTL.PPPTV....................
A0A0J5NHR8_PLUGE/5-141              ...............IKLLYIFEDLLSPDEFPRIVNP-----DQASHRLSYIPEKDI...LSLF......VGFRGSELIRRDAGVTHNGISADLRGKVQAALRRGDIVAVETRP..GVLA-TIGPFYADGEGQLIPYSSHE...-PGYPVDRIVRRYEDVVKS.....YGGRrARPS-l...................
A0A1W6B416_9GAMM/8-149              ..............n-RLICLSRDTLAPESFERIISPLAAWKHIEQDYRFDDSWNNS...LYIV......---NIFPKFAHPLAATLPEYGRRSKEQLKALTERGEVVCLNDVS..VL---PAGLFYIDDNGMLICRDKTL...FRFDGANRIIAAFNLAVSKrdyhhSGGK.PAPTS....................
A0A0H3CIY9_ENTCC/4-138              ...............IKFVYLFSENVSPALFAKIIHP-----SVAGQWIMSVPDNSL...RSLF......TRYDLL---HSITGANPYQSGRDIRKLIVQDLDMGRVVAIDESY..RNWSSVTEIFYINADGRLQAASLDG...LGWYPVSTIVDRYETMVRT.....YGSR.PAPTV....................
A0A6M8UGV8_9GAMM/8-148              ..............t-DLWYLARDNLAPERYEEIISPCFAWWRICKEYEFDDSYTHH...LYLI......---NMRPREGRVYTHQAPPHGPREQEKLKNWLYGGQAVMLDNRF..S----SGNLFYIDDQGQLICRDPLA...FRFSGAERIIKAYNLSVSRrdythNHGR.PRPTV....................
H5V5P2_ATLHE/8-150                  ...........hdlt--------RQLDPEDFQYILTPAGSLREACIHYDLSYEANGH...SLSFgl..pkQKYSISPH-QRPYERRHRSYADPIYDEVEHELQIGWLVGVDT-S..RRWSSDRNPFYIDDNGDLIFTPTAS..sWHAWYKDEITSAYQHAIAD....rQVRK.PAPTQ....................
A0A240C997_SERFI/1-142              ...............MRLIYFTSEDLEPELFARILKPTDARYELERHYLFG--GSSL...LSIS......ERHNITRNVQTGIGVSSYQENTNMKRGVFDEINRGSLLAIERGW..GSWSPAKYLFFINGDGLLQLYSGNH..lPAQYPVKRIIERYEDMVRK.....YAVR.ARPT-a...................
A0A6M8U6R4_9GAMM/8-147              ..............c-DLFYLPRDNLAPERYALITQPIIARRYICDHYEFFDENTSP...HIIA......MRHRYS----SLSTLHQPAGGKLAQERLKRMVLHGQVIMLDR--..--YSAPGRLFYIDDQGQLICRHPWL...FELSGADHIIRAYRDSVACrdyrhHGGK.PQAT-s...................
A0A830ZER2_9ENTR/1-131              ..............m------------PKDYENILAPDIAKNIIKKEYFIESSPNNL...LGSI......DGYSIKPHHGFKYGLPHDPLGHQKENYIDSLIDKGIVVVVRPNI..SSRNRFYYPFFISESAELFCVQSLS...FNAVFVRTIINGFKDSVAV.....HGR-.PAPT-r...................
A0A240B422_SERFI/1-142              ...............MKLTYLTFEHTAPESFPWILGPAEARYALERNYLFG--GAAG...MSIC......SRHHITRNTQSGIGITDYREDAAMKRQVLDDINCGRLLAIDERL..GAWSPTKNAFYVNTEGRLQRYPGSQ..lPALYPTERVIARYEDMVRR.....YGYR.AKPTV....................
A0A1C3ZMD4_9ENTR/1-142              ...............MDIYDIRKRNLLPKDFENILAPDIAKNIIKKEYFIESSPNNI...LGSI......DGYTIKRHHGFKYGLPHDPLGHQKEKHIDSLVDKGVVVVARPNV..STRSRFYYPFFIAENGDLFCVQPLS...FNAVFIRTILNGFKDSVAM.....HGR-.PAPT-r...................
A0A2N5EI89_9GAMM/6-153              ..........mkwea-------SEELNPEDIQFILSPSKAMKLAAIFYELDYAQYHQ...QHCPrmrvpeRRRGVHRYFSQPYKRKPAGHYDGLYDDIEWNIRLGWMVGIDT-S..EPWDHFSNPFYFDKDSNLIFDCFMD..yGTEMFEQEVRSIYERSLNN....hHGRK.PDPTV....................
A0A2U2GYB9_YERPE/8-77               ...............IYLYNLSRDNLRPEEYERIVSAYAAWTRVCREYEFNDGYHAN...HYII......---NMRERQVHHTQASSL--------------------------..-------------------------...-------------------.....----.-----gprekdkle...........
Q0WJ32_YERPE/8-148                  ...............MYLYYLSRDNLAPEEYERIISPHAAWARICREYEFDDSHNTS...RYLI......---NMREREQRSSPDQPRPGGIREKEKLEKLVFSGDVVMLSDMY..G----PARLFYINGEGQLMSTDPHA...FRFEGAAKIIKAFDDSVKCrnyqrTGGK.PRSTQ....................
B2VHH3_ERWT9/13-154                 ...............MKLIFFSYENTEPESFSRIISPANARSELDRSYLFG--GAAQ...MSIC......SRYNIMRKRQSGRDIPGFAEEPGVKRHVFDEINHGSLLAIDEVF..AVWSPLKHPFYIDEKGKLQRYPGSY..lPAMYPVSRIIGRYEEMVSR.....YARR.PRPT-p...................
#=GC seq_cons                       .................lh.l.p-pLsPEpappIlsP..AhtplspcY.hs...ss....h.lh.........shp...tpshthp....stthpctl.p.lptGplVslcp....t.hs.stp.FYIsspGpLhhtssht....thh.hppIlptYcp.Vpp.....hut+.PtPT.....................
//