#=GF ID   DdMyo7_FERM
#=GF AC   PF22406.2
#=GF DE   DdMyo7 FERM domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   ECOD:EF24789
#=GF GA   27.00 27.00;
#=GF TC   27.00 28.10;
#=GF NC   26.90 26.60;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 90746521 --cpu 8 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0632
#=GF RC   Paper describing PDB structure 5ejr
#=GF RN   [1]
#=GF RM   27166421
#=GF RT   Myosin MyTH4-FERM structures highlight important principles of
#=GF RT   convergent evolution.
#=GF RA   Planelles-Herrero VJ, Blanc F, Sirigu S, Sirkia H, Clause J,
#=GF RA   Sourigues Y, Johnsrud DO, Amigues B, Cecchini M, Gilbert SP,
#=GF RA   Houdusse A, Titus MA;
#=GF RL   Proc Natl Acad Sci U S A. 2016;113:E2906-E2915.
#=GF DR   INTERPRO; IPR055159;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents the C-terminal FERM domain found in Myo7
#=GF CC   from Dictyostelium discoideum [1], a protein that is essential
#=GF CC   for the extension of filopodia, plasma membrane protrusions
#=GF CC   filled with parallel bundles of F-actin similarly as metazoan
#=GF CC   Myo10, which suggests a high degree of functional conservation
#=GF CC   throughout evolution.
#=GF SQ   6
#=GS D3BST1_HETP5/2193-2303      AC D3BST1.1
#=GS F4PGT3_CACFS/2229-2339      AC F4PGT3.1
#=GS MYOI_DICDI/2154-2264        AC Q9U1M8.1
#=GS A0A152A126_TIELA/2065-2175  AC A0A152A126.1
#=GS F0Z7K7_DICPU/2096-2206      AC F0Z7K7.1
#=GS A0A8J4Q311_9MYCE/2080-2190  AC A0A8J4Q311.1
D3BST1_HETP5/2193-2303                 .VKILDQEHLWTTDETAFELTFLQIREEWMRGMYW-ISERDISYAASILIQLAYPNQSKLQIsNKDLLKQVIPDVLF..QGQNIKFWSSNIETHIFELVSHTQEYLKLLFLQQMG...................
F4PGT3_CACFS/2229-2339                 .TRIVDQEHLWTNDETSFDLTYTQLREEWIRGVYT-LSDKDASAASAILVQLAHPNQSRLQLgTKEALRPFMPESIM..SSQNTKYWASEIESLLFEMVSHTPEYLKLLFIQTLG...................
MYOI_DICDI/2154-2264                   .NKILDQEHLWTDDDICFELTYCQIRDEWMKGLYTNVNEKDSSIIAAILIQLLYPNQSKLVL.TKEVVRQVLPDQIL..NSQNIKVWISMIESQIFELVSQTPEYLKLMFINLIG...................
A0A152A126_TIELA/2065-2175             .TKIMTQENLWTDDEVSFELTFRQIREEWMKAHYLTVNEKDISLLAAILIQLDHPNQSKLQF.NKELLKQMIPDQLF..NTQNIKFWTSQIESQIFELVSHTPEYLKLLFIQAIG...................
F0Z7K7_DICPU/2096-2206                 .NKILEQEHLWTDDDISFELTFVQIRDEWMRGLHSTLNEKDSAVAAAILIQLLYPNQSKLIF.TKEIIRQALPDNII..AQQNIKFWISTVESQIFELVSQTPEYLKLMFIHLVG...................
A0A8J4Q311_9MYCE/2080-2190             s-KILNQEHLWTDDEVCFDLTYLQVRDEWTKGLYSSLSEKDVATGAALLIQLSHPNQSKLQF.NKELLRQCMPEANF..SSQNIKFWTALIESQIFELVSHTAEYLKLLFIQLIG...................
#=GC seq_cons                          .sKIL-QEHLWTDDEluFELTahQIR-EWM+GlYoslsEKDsShuAAILIQLsaPNQSKLQh.sKElLRQslPDslh..soQNIKFWsSpIESQIFELVSHTPEYLKLLFIQhlG...................
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