GenomeNet

Database: Pfam
Entry: DisA
LinkDB: DisA
Original site: DisA 
#=GF ID   DisA
#=GF AC   PF19226.2
#=GF DE   DisA glycoprotein
#=GF AU   Karlin D;0000-0002-3033-7013
#=GF SE   David Karlin
#=GF GA   27.00 27.00;
#=GF TC   255.00 59.90;
#=GF NC   26.20 25.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   24155369
#=GF RT   Powerful sequence similarity search methods and in-depth manual
#=GF RT   analyses can identify remote homologs in many apparently
#=GF RT   "orphan" viral proteins.
#=GF RA   Kuchibhatla DB, Sherman WA, Chung BY, Cook S, Schneider G,
#=GF RA   Eisenhaber B, Karlin DG;
#=GF RL   J Virol. 2014;88:10-20.
#=GF DR   INTERPRO; IPR043638;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry corresponds to a putative viral glycoprotein [1].
#=GF SQ   8
#=GS A0A2L2P6U1_9VIRU/36-374   AC A0A2L2P6U1.1
#=GS A0A1U7EIU8_9VIRU/34-381   AC A0A1U7EIU8.1
#=GS A0A1Z2RT13_9VIRU/51-409   AC A0A1Z2RT13.1
#=GS W5VG83_9VIRU/46-418       AC W5VG83.1
#=GS A0A1L3KJW4_9VIRU/37-395   AC A0A1L3KJW4.1
#=GS A0A088D9X0_9VIRU/52-410   AC A0A088D9X0.1
#=GS A0A023Q224_9VIRU/74-403   AC A0A023Q224.1
#=GS A0A023Q224_9VIRU/378-589  AC A0A023Q224.1
A0A2L2P6U1_9VIRU/36-374              .................................................................q-VTEDRYRTFLDYYDTADVKAYDLSWASKFFKDPvCHNGWVLHLLSNSAFRDeYYLCVRTEGN....KKRLIETTQLRF.SDQQQWIFSDA---DN..QVGVIVLELDIPNKYIFYKDGDDLYMTTPMCMSNHYYLTDDKIFPPEPPIENKKNFIKY-FYTYQCR...PVRVHNTLKQ---.....LPIEVKW.....------.RVAGGQgysPEYVvfledafKSNLLRQLDQDAFVPTDNLYYSPD------YNVTIMDTPSVYAVKYLNHL..PdyeiiYFEHITSNF-----------FLDLI...EFVLDRVISLIVTILSTIFNF-----.--------------VLEK............................INQYVFSNIpyyFKSFYEFFFSLDPYVKFLIMSFVLIYIKTTKFIKTIFLVFLLTLFT-y...............
A0A1U7EIU8_9VIRU/34-381              .................................................................m-LDIELIGKLYSLQPFSDFKVYEANAWNKLIGYH.CPSGQTVYPLEHSFLKD.LYTCIPKPKV....LNSQYLVYRIKPsSHDNVTVQCKNRYYNV..----SVAFCQIESYRFLIDNKGDTWFTSDYCLSNRYMTDNDGKELFTVSHTSTDYSVTFEFPPPECP...FY--PYDVYYEKS.....LPATVCI.....DSSPEF.------...KSCVt....gaKCEVHPPYELLPVSTHSELHFKVNGTCSVAFMTFTEPTT-----------..-.....ITYHIKSALSTSFIDAVLHALLSLL...RPLIDALLELVTYIIDTLVTIFTSSE.FVAIYQKIYHLILSVLQN............................VFDYIIDVA...VPKIMDLFYESTLKTKFIILTFIYVYFKYTKFIYALSVCVVVCLFF-s...............
A0A1Z2RT13_9VIRU/51-409              ..................................................................LFTFKQFSTIYRSDIFNDFKIYHANAWNEFVGIS.CPEHHVPYYLVHHIFSA.IYVCLPVPHV....LEPLYTAYELIL.GETNFWIFCGLTG-SS..SEFAKFTPKDYTDYLILVDSNNKYHLSSKYCVGHMYQVGPDNKEIMTLNYTVNDHSVTLDLPSEHCK...ILPLPISKLDFTL.....LPIEVDV.....KSSVDV.------...LDCL.......--RVERSSNLHPEKPFFEL--ALDDTTLLTYNTSTNGSHNFAYIWFSSHQfpT.....KTFHISSAVNVNPLSWIITGLMSFF...YPLLDMLLSSILYIFESVLDIFESHT.FLDLFDRLLNVVITILTR............................IFQFFVSTI...FPRIVDLLNRIPTRYKFLFGLMFVLYLKTTKLLFSFCITVLVHFCIK................
W5VG83_9VIRU/46-418                  .................................................................l-LSFDFEYNIYGKYVEDDIKVYHANAWSKFIGSH.CPPNHHKVSLQHHIFSE.LYVCIHVPTV....LKNPHSVYKINK.NYNEVLVSCYLPGGDEfaIETIRVDIPDLDKFRII-EFNGKNFLTSQYCISDRYGLTSDHKEVLQVNYTVTDNTISFQFPKGECRkdsQLIWDIDSLHPGY....yLPFVINI.....TASTNM.------...HKCLtyyytpyDTELDTNVTVLPLTPTEHLIWAVDVSPIIV------DARNLTRVWSSINY.yPpp.sdTVIHIGSAITNSPFNFISSAILAIL...RPIIDILLDSLIYILSTLMEIFESSE.FLEIVNRLFDFVYLLIKN............................IFEFIVKVI...YPRLLDIVLSFSTKCKFLFVVFIITYIKTGKFFVTCIITFFVNMCMR................
A0A1L3KJW4_9VIRU/37-395              .................................................................n-VVFQHEFDILDKHLSSEVQIYSTNFYSHIVGAN.CPVGFHRQDINHYTFSD.IFACIYHGYTdiysLPVKYRAYSLRL.TSNVIDRYS-------..----TIQYINLHEFLVLKNDTG-YYLSTRFCFNEYPWKDINGTIQPHLYFENHDTFVKF-YVSNSCL...LRYLTTDAEHLTYyifsqIPSLFDLevktpNSAVDFfRVGFVK...YHWL.......---------------HHTL--SPGDLPYMDYNATHSITKHCYSVEYCVAVyyPvqrlfTTIAIQSAHANSFVHSLTHAILSIL...KPILVEILSLMSFLFGSIIDLIFSSE.FIDLYKLFFDNFIKALHQ............................ILTFIFTN-...FRLLIYYLLTNHIYFSMGLFLFLLIYIRYGMLVYSFIFVLLLSSLV-r...............
A0A088D9X0_9VIRU/52-410              .................................................................f-LTFKKFSTIYRSELFTDFKIYHANAWNKFLGVS.CAGNHVPYALTHHIFSE.IYVCLPFPPV....LEPIYTAYELVP.RERNFFIPCGMTG-EK..STFANFEPMNYKDYLVLQDPKGKFHLSSKYCVGHMYQIGLNNKEILTVNYTVTDYSVTIDYPSSYCN...VFPLPIKFLDFTL.....LPIVVRV.....KSTLDV.------...IDCL.......--RVERSSNVVAGRPMYEL--AIDDVTLLRYNTTTNGTHNFAYTYKSRHSypT.....KTFHISAAANVNPFTWVTTGLLTLL...TPILDFLLNSFLYCFESLLNIFESTP.FLNLFDRLLHFIYNIISL............................ISKFIATHI...FPKILTFIKNIPIRYKFLLVFLFVMYLKTTKFIFSCCVTALIHLCIK................
A0A023Q224_9VIRU/74-403              ..................................................................LWQLKYHSNVYDSELSKEIVVHTANAWNKFIGYH.CPPNHYKHVLQHEFFSD.VYVCVKIPQP....LKKIYTAYSLVQ.AYDIIALRCYSTPVNT..IDHFYITIVDVDQWYLLKDGGGSEYLISKYCLNYWYQIDSHGNELFDLKFTVSKGVVTFHLPKHSCS...-------------.....-PLKIDF.....SSANNIlNVQIRGgrtLECI.......KRQLFRNYNYNCNIPYKNLTFTHN--KLMLYRTNDCPSTLYESVESED--..-.....ISIHVESSSGASPFSFITTALLQVM...KPVLDFVLDSLMTIINEFVTIYESPE.FIEIFTRIFDTFAKFVRI............................ILDFITKP-...--EIMNLFVHI------------------------------------letalkiiqsvldffk
A0A023Q224_9VIRU/378-589             peimnlfvhiletalkiiqsvldffkkprlkvvflriimiiedfvvttldyifksdsvnnilskgl----------------------------------.-----------------.----------....------------.----------------..-------------------------------------------------------------------...-------------.....-------.....------.------...----.......--------------------------------------------------..-.....-----------TFIEKIIKMLTRFIkqaKGTIEEVIKLVFSLIEQIVNLIIGDEqIIKIFVKFVTLIEHTLMQiigyllksnllrdlinsvftllvhvsniIFDFISLTI...VPQVIHVFMNLSFKVKIMFAVFLICYIKSSKFFWSIVIALIFSCFI-g...............
#=GC seq_cons                        ...................................................................lshchhtslYcppl.sDhKlYcANAWsKFlGhp.CPssahhasLpHphFS-.lYlCl.hPts....LcshYpsYpLh..spsphhl.Ch....sp....hhplp.hslcpahlLh-ssGchaLoScYCluphY.lsscspElhplsaTssDtsVoapaPstpCp....h.hshshhp.t......LPhhlcl.....pSussh..........hcCl.........pl.ps.sh.s.hPhppL..uhss.shhhYpssppsopphh.l..p.t...s.....hohHIpSAhsso.hshlhpuLLsll...+PlLDhlLs.lhaIlsollsIapSsE.Flclas+lhchlhplLpp............................IhcFIsssI...aPcllclhhslsh+hKFlhhhFllhYlKooKFlaohhlshllshhh.................
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