GenomeNet

Database: Pfam
Entry: EGF_MSP1_1
LinkDB: EGF_MSP1_1
Original site: EGF_MSP1_1 
#=GF ID   EGF_MSP1_1
#=GF AC   PF12946.10
#=GF DE   MSP1 EGF domain 1
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Jackhmmer:P04933
#=GF GA   27.00 27.00;
#=GF TC   27.00 27.00;
#=GF NC   26.90 26.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0001
#=GF RN   [1]
#=GF RM   10339410
#=GF RT   Solution structure of an EGF module pair from the Plasmodium
#=GF RT   falciparum merozoite surface protein 1.
#=GF RA   Morgan WD, Birdsall B, Frenkiel TA, Gradwell MG, Burghaus PA,
#=GF RA   Syed SE, Uthaipibull C, Holder AA, Feeney J;
#=GF RL   J Mol Biol. 1999;289:113-122.
#=GF DR   INTERPRO; IPR024730;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This EGF-like domain is found at the C-terminus of the malaria
#=GF CC   parasite MSP1 protein. MSP1 is the merozoite surface protein 1.
#=GF CC   This domain is part of the C-terminal fragment that is
#=GF CC   proteolytically processed from the the rest of the protein and
#=GF CC   is left attached to the surface of the invading parasite.
#=GF SQ   83
#=GS A0A2G8KYQ3_STIJA/39-74      AC A0A2G8KYQ3.1
#=GS K6UX91_PLACD/363-402        AC K6UX91.1
#=GS K1QGK1_CRAGI/2467-2504      AC K1QGK1.1
#=GS H0Z6C6_TAEGU/197-232        AC H0Z6C6.2
#=GS A0A671V848_SPAAU/12-48      AC A0A671V848.1
#=GS A0A384L5M2_PLAKH/1772-1807  AC A0A384L5M2.1
#=GS A0A1J1H3N0_PLARL/1490-1526  AC A0A1J1H3N0.1
#=GS A0A6J1SQK6_FRAOC/532-569    AC A0A6J1SQK6.1
#=GS A7SBC0_NEMVE/284-319        AC A7SBC0.1
#=GS E4X8F9_OIKDI/457-494        AC E4X8F9.1
#=GS A0A6P6LK11_CARAU/284-319    AC A0A6P6LK11.1
#=GS A0A0D8Y6J0_DICVI/783-819    AC A0A0D8Y6J0.1
#=GS G3W254_SARHA/185-221        AC G3W254.2
#=GS MSP1_PLAYO/1662-1700        AC P13828.1
#=GS MSP1_PLAYO/1662-1700        DR PDB; 2MGR A; 7-45;
#=GS MSP1_PLAYO/1662-1700        DR PDB; 2MGP A; 7-45;
#=GS A0A6P8HN52_ACTTE/1558-1593  AC A0A6P8HN52.1
#=GS T1KLJ0_TETUR/640-676        AC T1KLJ0.1
#=GS A0A4X3PF03_PRIPA/304-340    AC A0A4X3PF03.1
#=GS A0A6P8ZQR1_THRPL/445-482    AC A0A6P8ZQR1.1
#=GS A0A443SBB5_9ACAR/268-306    AC A0A443SBB5.1
#=GS A0A1A8WY67_PLAMA/302-336    AC A0A1A8WY67.1
#=GS W4IYZ7_PLAFP/1547-1583      AC W4IYZ7.1
#=GS A7ST24_NEMVE/412-447        AC A7ST24.1
#=GS U3K2S4_FICAL/199-234        AC U3K2S4.1
#=GS A0A3L8SB38_CHLGU/199-234    AC A0A3L8SB38.1
#=GS A0A0K0ELR8_STRER/1868-1903  AC A0A0K0ELR8.1
#=GS A0A484CB48_PERFV/1041-1077  AC A0A484CB48.1
#=GS A0A6P8Z7Z3_THRPL/516-553    AC A0A6P8Z7Z3.1
#=GS V8P6B4_OPHHA/164-199        AC V8P6B4.1
#=GS A0A1A8W1E4_PLAMA/371-410    AC A0A1A8W1E4.1
#=GS A0A679L3P5_PLAKH/1717-1753  AC A0A679L3P5.1
#=GS E9G6S4_DAPPU/632-668        AC E9G6S4.1
#=GS A0A672ZVT5_9TELE/221-256    AC A0A672ZVT5.1
#=GS A0A4W5S1K9_9TELE/204-241    AC A0A4W5S1K9.1
#=GS A0A6P8Z7Z6_THRPL/416-453    AC A0A6P8Z7Z6.1
#=GS A0A669Q6D6_PHACC/199-234    AC A0A669Q6D6.1
#=GS W7KFP9_PLAFO/1612-1648      AC W7KFP9.1
#=GS A0A7N4PTT9_SARHA/173-209    AC A0A7N4PTT9.1
#=GS A0A024VR46_PLAFA/1583-1619  AC A0A024VR46.1
#=GS A0A6P8HN52_ACTTE/1270-1306  AC A0A6P8HN52.1
#=GS A0A6P8Z7I1_THRPL/537-574    AC A0A6P8Z7I1.1
#=GS A7RF84_NEMVE/97-130         AC A7RF84.1
#=GS E4X0M8_OIKDI/324-361        AC E4X0M8.1
#=GS A5K723_PLAVS/1754-1789      AC A5K723.1
#=GS A0A0B1SAM9_OESDE/43-75      AC A0A0B1SAM9.1
#=GS D4AFN2_PLAGO/1607-1643      AC D4AFN2.1
#=GS B9QP44_TOXGV/610-647        AC B9QP44.1
#=GS A0A024WQJ1_PLAFA/1601-1637  AC A0A024WQJ1.1
#=GS A0A1Y1JCZ7_PLAGO/1917-1952  AC A0A1Y1JCZ7.1
#=GS A0A3P8ZT82_ESOLU/131-168    AC A0A3P8ZT82.2
#=GS A0A1A8YQM1_9APIC/1575-1611  AC A0A1A8YQM1.1
#=GS A0A1A8VP40_9APIC/1623-1659  AC A0A1A8VP40.1
#=GS A0A1D3JMS5_PLAMA/1699-1735  AC A0A1D3JMS5.1
#=GS W7JYM8_PLAFA/1610-1646      AC W7JYM8.1
#=GS K6UUJ2_PLACD/1692-1728      AC K6UUJ2.1
#=GS A0A0L7KDM6_PLAFX/1519-1555  AC A0A0L7KDM6.1
#=GS A0A024X9M2_PLAFC/1438-1474  AC A0A024X9M2.1
#=GS A0A1D3U8A2_9APIC/1617-1653  AC A0A1D3U8A2.1
#=GS A0A0L7LXP3_PLAF4/1589-1625  AC A0A0L7LXP3.1
#=GS A0A7R5KEZ7_9PASS/199-234    AC A0A7R5KEZ7.1
#=GS A0A6P8HN52_ACTTE/1150-1186  AC A0A6P8HN52.1
#=GS A7T8E5_NEMVE/364-401        AC A7T8E5.1
#=GS H3DI89_TETNG/985-1021       AC H3DI89.1
#=GS A0A672ZVJ5_9TELE/221-256    AC A0A672ZVJ5.1
#=GS A0A509ALB2_PLABA/1682-1719  AC A0A509ALB2.1
#=GS A7ST24_NEMVE/125-160        AC A7ST24.1
#=GS A0A669QDX8_PHACC/199-234    AC A0A669QDX8.1
#=GS A0A024W7K7_PLAFA/740-776    AC A0A024W7K7.1
#=GS Q8I0U8_PLAF7/1612-1648      AC Q8I0U8.1
#=GS A0A653HE52_9APIC/522-558    AC A0A653HE52.1
#=GS A0A3P8XXH8_ESOLU/131-168    AC A0A3P8XXH8.2
#=GS A0A3M6UYT4_POCDA/1471-1506  AC A0A3M6UYT4.1
#=GS A0A0L0CYS7_PLAFA/1567-1603  AC A0A0L0CYS7.1
#=GS A0A226DPX4_FOLCA/555-585    AC A0A226DPX4.1
#=GS A5K724_PLAVS/1646-1682      AC A5K724.1
#=GS A0A226NXS7_COLVI/85-120     AC A0A226NXS7.1
#=GS A7RF88_NEMVE/99-136         AC A7RF88.1
#=GS A7ST24_NEMVE/164-201        AC A7ST24.1
#=GS K6URU2_PLACD/1744-1779      AC K6URU2.1
#=GS A0A553PLA7_TIGCA/11-51      AC A0A553PLA7.1
#=GS A0A6P8ZCF0_THRPL/466-503    AC A0A6P8ZCF0.1
#=GS A0A384LJW0_PLAKH/371-410    AC A0A384LJW0.1
#=GS A0A3S0ZYK1_ELYCH/245-283    AC A0A3S0ZYK1.1
#=GS A0A0L1I842_PLAFA/1577-1613  AC A0A0L1I842.1
A0A2G8KYQ3_STIJA/39-74                 ........TCLD..I...K..CDENAQCTE.QD.-G...VRGCYCNPGF...E..G.DGIT..C-t...........
K6UX91_PLACD/363-402                   ........VCEH..K...K..CPLNSNCYV.ID.-G...EEVCRCLPGF...S..D.----..--vkidnvmncv..
K1QGK1_CRAGI/2467-2504                 ..ecilrt----..A...N..CPANSACVN.QN.-P...GYECRCLTGY...Q..K.VGSL..C-t...........
H0Z6C6_TAEGU/197-232                   .......l-CKG..V...T..CEANSECVV.RD.-G...TALCDCKLGY...R..K.QGST..CQ............
A0A671V848_SPAAU/12-48                 .......e-CLL.nS...T..CPEHSTCIN.TN.-G...SRLCICDGGF...S..S.VGDL..CV............
A0A384L5M2_PLAKH/1772-1807             ........NCRN..R...K..CPPNSFCFI.ET.-F...NEECLCFLNY...N..M.VGGK..CI............
A0A1J1H3N0_PLARL/1490-1526             .......i-CIN..T...V..CPINSGCIR.RL.NG...KEECRCLLNF...K..K.EGMM..CV............
A0A6J1SQK6_FRAOC/532-569               .......l-CPD.gT...D..CDQNADCVR.HT.AN...SYRCRCRVGF...A..G.DGHI..C-g...........
A7SBC0_NEMVE/284-319                   ........ECQN..N...P..CPLNSICSN.TI.-G...SYDCACQPNY...V..K.SGER..CI............
E4X8F9_OIKDI/457-494                   .......v-CAS.aS...P..CDANASCTN.NA.DG...SQSCECNFDF...K..G.DGYT..C-t...........
A0A6P6LK11_CARAU/284-319               ....lsfn----..-...P..CDTNAHCFI.ER.NG...DVTCACNVGW...V..G.NGHT..C-g...........
A0A0D8Y6J0_DICVI/783-819               ........TCGQ..H...V..CDMNAECMP.SS.SG...GTECVCKLGY...V..G.NGVT..CE............
G3W254_SARHA/185-221                   .......a-CKD..L...A..CPQNSQCVN.TD.TG...APSCKCLPGY...R..L.QGTK..CQ............
MSP1_PLAYO/1662-1700                   ........VCVD.tR...D..IPKNAGCFR.DD.NG...TEEWRCLLGY...K..KgEGNT..CV............
#=GR MSP1_PLAYO/1662-1700        SS    ........--S-.-S...S..--TTEEEEE.-T.TS...-EEEEE-TTE...E..E-SSSS..EE............
A0A6P8HN52_ACTTE/1558-1593             ........ECIK..D...P..CPPMSQCVN.AF.-G...TYVCQCKPGY...K..K.SNGL..CE............
T1KLJ0_TETUR/640-676                   .......m-CGD..K...F..CDPNADCLP.ST.DG...SKKCICLPGF...T..G.NGII..C-r...........
A0A4X3PF03_PRIPA/304-340               .......e-CLI.hG...I..CPAFSNCTN.TP.-G...SYECTCITGF...K..K.ENGK..CV............
A0A6P8ZQR1_THRPL/445-482               .......l-CPD.gT...D..CDQNADCVR.HT.AN...SYRCRCRVGF...A..G.DGLV..C-g...........
A0A443SBB5_9ACAR/268-306               .......a-CPD.gT...Q..CDANADCFR.HR.-Gh.sRYYCRCKVGF...S..G.DGFM..C-a...........
A0A1A8WY67_PLAMA/302-336               .......i-CEY..S...K..CGANARCYI.VD.KD...KEECRCRANY...V..Q.DT--..--sv..........
W4IYZ7_PLAFP/1547-1583                 ........QCVK..K...Q..CPENSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
A7ST24_NEMVE/412-447                   ........ECLK..G...P..CPQNAKCVN.NF.-G...SYLCICNPGY...K..K.VNGK..CE............
U3K2S4_FICAL/199-234                   .......l-CRG..V...T..CEANSECVV.RD.-G...AALCDCKLGY...T..K.QGST..CQ............
A0A3L8SB38_CHLGU/199-234               .......l-CKG..V...T..CEANSECVV.RD.-G...TALCDCKLGY...R..K.QGST..CQ............
A0A0K0ELR8_STRER/1868-1903             .....sig---S..H...S..CDKNAKCIS.KS.NG...EYTCICNPGF...-..-.----..--idkspnk.....
A0A484CB48_PERFV/1041-1077             ........ECLD.nS...T..CPEHSTCIN.NN.-G...SNLCICDAGF...S..S.VEDL..CV............
A0A6P8Z7Z3_THRPL/516-553               .......l-CPD.gT...D..CDQNADCVR.HT.AN...SYRCRCRVGF...A..G.DGLV..C-g...........
V8P6B4_OPHHA/164-199                   .....inp----..H...S..CDANAECIK.SG.PG...THECVCQPGW...T..G.NGRD..C-s...........
A0A1A8W1E4_PLAMA/371-410               ........VCEH..K...K..CPLNSNCYV.IN.-G...EETCRCLPGY...S..D.V---..--kldnemncv...
A0A679L3P5_PLAKH/1717-1753             ........KCID..T...N..VPENAACYR.YL.DG...TEEWRCLLGF...K..E.VGGK..CV............
E9G6S4_DAPPU/632-668                   .......p-CSR..V...R..CPVHSQCIE.NN.QG...HPECRCLAGY...Q..E.TESQ..CQ............
A0A672ZVT5_9TELE/221-256               ........ECTE..S...P..CDPNASCIN.RL.-G...SYECVCNSGF...L..E.EGLT..C-t...........
A0A4W5S1K9_9TELE/204-241               ........ECSS..L...L..CPQNTRCMQgSL.DG...SLRCQCLPGY...Q..T.SGDQ..CI............
A0A6P8Z7Z6_THRPL/416-453               .......l-CPD.gT...D..CDQNADCVR.HT.AN...SYRCRCRVGF...A..G.DGLV..C-g...........
A0A669Q6D6_PHACC/199-234               .......l-CRG..V...R..CEANSECVV.KD.-G...TAMCNCKLGY...R..K.SGST..CV............
W7KFP9_PLAFO/1612-1648                 ........QCVK..K...Q..CPENSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
A0A7N4PTT9_SARHA/173-209               .......a-CKD..L...A..CPQNSQCVN.TD.TG...APSCKCLPGY...R..L.QGTK..CQ............
A0A024VR46_PLAFA/1583-1619             ........QCVK..K...Q..CPQNSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
A0A6P8HN52_ACTTE/1270-1306             .......s-CGG..V...K..CDPNAKCIQ.IA.QG...VRQCVCNAGW...E..K.NGNT..CI............
A0A6P8Z7I1_THRPL/537-574               .......l-CPD.gT...D..CDQNADCVR.HT.AN...SYRCRCRVGF...A..G.DGLV..C-g...........
A7RF84_NEMVE/97-130                    .....sva----..-...T..CPASADCVN.ND.-G...SYTCRCKPGY...E..L.NNNE..CE............
E4X0M8_OIKDI/324-361                   ........VCAN.aN...P..CDANAACAN.NA.DG...SQTCTCNDGY...K..G.DGSE..C-t...........
A5K723_PLAVS/1754-1789                 ........NCRN..R...K..CPLNSFCFI.QT.-I...NEECLCLLNY...S..M.VGEK..CI............
A0A0B1SAM9_OESDE/43-75                 .......i-CKG.kD...D..CPANSFCFQ.QL.--...---CRCMLGY...R..A.NGGY..CE............
D4AFN2_PLAGO/1607-1643                 ........KCID..T...V..VPENAACYR.YL.DG...REEWRCLLKF...K..L.DGGK..CV............
B9QP44_TOXGV/610-647                   .......e-CEAepE...R..IPPNATCVN.TD.-G...SFEWSCNAGY...E..H.VGSQ..CQ............
A0A024WQJ1_PLAFA/1601-1637             ........QCVK..K...Q..CPENSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
A0A1Y1JCZ7_PLAGO/1917-1952             ........NCSN..K...R..CPPNSFCFI.DE.-Y...DEECFCFLNY...T..M.IGKN..CI............
A0A3P8ZT82_ESOLU/131-168               ........ECSA..L...Q..CPENTRCIQ.STlDG...SLRCQCLPGY...Q..T.LGNQ..CI............
A0A1A8YQM1_9APIC/1575-1611             ........KCID..I...T..YPDNAGCYR.FP.DG...REEWRCLLNF...K..K.VGET..CV............
A0A1A8VP40_9APIC/1623-1659             ........KCID..I...T..YPDNAGCYR.FS.DG...REEWRCLLNF...K..K.VGET..CV............
A0A1D3JMS5_PLAMA/1699-1735             .......a-CTE..T...K..YPENAGCYR.YE.DG...KEVWRCLLNY...K..L.VDGQ..CV............
W7JYM8_PLAFA/1610-1646                 ........QCVK..K...Q..CPENSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
K6UUJ2_PLACD/1692-1728                 .......r-CID..T...N..VPENAACYR.YL.DG...TEEWRCLLYF...K..E.DAGK..CV............
A0A0L7KDM6_PLAFX/1519-1555             ........QCVK..K...Q..CPQNSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
A0A024X9M2_PLAFC/1438-1474             ........QCVK..K...Q..CPENSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
A0A1D3U8A2_9APIC/1617-1653             ........KCID..I...T..YPDNAGCYR.FS.DG...REEWRCLLNF...K..K.VGET..CV............
A0A0L7LXP3_PLAF4/1589-1625             ........QCVK..K...Q..CPENSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
A0A7R5KEZ7_9PASS/199-234               .......l-CKG..V...T..CEPNSECVV.RD.-G...TAECACKLGY...R..K.LGST..CQ............
A0A6P8HN52_ACTTE/1150-1186             .......s-CGG..V...T..CDAKARCVQ.TP.QG...TRQCVCNTGW...Q..K.NGNR..CI............
A7T8E5_NEMVE/364-401                   .ecalgva----..-...T..CPASADCVN.ND.-G...SYTCRCKRGY...T..L.VNKT..C-t...........
H3DI89_TETNG/985-1021                  .....ecq--VN..S...T..CPEHSMCIN.TN.-G...SYLCVCNDGF...S..K.VGEL..CV............
A0A672ZVJ5_9TELE/221-256               ........ECTE..S...P..CDPNASCIN.RL.-G...SYECVCNSGF...L..E.EGLT..C-t...........
A0A509ALB2_PLABA/1682-1719             ........VCIN.tR...D..IPANAGCFR.YD.NG...NEEWRCLLGY...K..K.NNNT..CI............
A7ST24_NEMVE/125-160                   ........ECES..V...S..CPANADCIN.SA.-G...SYECRCRLGF...S..K.NGSE..CQ............
A0A669QDX8_PHACC/199-234               .......l-CRG..V...R..CEANSECVV.KD.-G...TAMCNCKLGY...R..K.SGST..CV............
A0A024W7K7_PLAFA/740-776               ........QCVK..K...Q..CPQNSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
Q8I0U8_PLAF7/1612-1648                 ........QCVK..K...Q..CPENSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
A0A653HE52_9APIC/522-558               .......a-CIN..T...E..VPTNAGCYR.YD.DG...REEWRCLLNY...K..K.HENQ..CI............
A0A3P8XXH8_ESOLU/131-168               ........ECSA..L...Q..CPENTRCIQ.STlDG...SLRCQCLPGY...Q..T.LGNQ..CI............
A0A3M6UYT4_POCDA/1471-1506             ........ECST..N...P..CDDNAFCLN.IK.-G...SYECTCLPGF...E..G.DGET..C-t...........
A0A0L0CYS7_PLAFA/1567-1603             ........QCVK..K...Q..CPENSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
A0A226DPX4_FOLCA/555-585               ........TCGS..R...V..CGAHADCIQ.FD.DG...NYECYCPPG-...-..-.----..--lhg.........
A5K724_PLAVS/1646-1682                 ........TCID..T...N..VPDNAACYR.YL.DG...TEEWRCLLTF...K..E.EGGK..CV............
A0A226NXS7_COLVI/85-120                .......l-CRG..V...S..CESNSECVV.KD.-G...TAMCNCKLGY...K..K.SGSI..CI............
A7RF88_NEMVE/99-136                    .ecalgva----..-...T..CPASADCVN.ND.-G...SYTCRCKRGY...T..L.NNNT..C-t...........
A7ST24_NEMVE/164-201                   ........TCGG..V...A..CDAHAQCVQ.HA.DG...RRECVCNAGW...V..Q.DAGR.aCL............
K6URU2_PLACD/1744-1779                 .......d-CRN..R...K..CPSNSFCFI.QT.-F...NENCLCFLNY...N..M.VGEK..CI............
A0A553PLA7_TIGCA/11-51                 .......p-CKD.nG...P..CPAGAQCYD.RS.DTlrpKYECICQMGM...V..M.EGNR..CI............
A0A6P8ZCF0_THRPL/466-503               .......l-CPD.gT...D..CDQNADCVR.HT.AN...SYRCRCRVGF...A..G.DGLV..C-g...........
A0A384LJW0_PLAKH/371-410               ........VCEH..K...K..CPLNSNCYV.ID.-G...EEVCRCLPGF...S..D.----..--vkidnvmncv..
A0A3S0ZYK1_ELYCH/245-283               ...ectnp--VK..Y...P..CPANSNCVE.SP.-G...SYFCQCLTGF...A..Y.DNGT..CV............
A0A0L1I842_PLAFA/1577-1613             ........QCVK..K...Q..CPENSGCFR.HL.DE...REECKCLLNY...K..Q.EGDK..CV............
#=GC SS_cons                           ........--S-.-S...S..--TTEEEEE.-T.TS...-EEEEE-TTE...E..E-SSSS..EE............
#=GC seq_cons                          .........Chs..p...p..CPtNusChp.ps..G...stcCpChhGa...p..p.sGsp..C.............
//
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