#=GF ID   Endotoxin_mid
#=GF AC   PF09131.15
#=GF DE   Bacillus thuringiensis delta-Endotoxin, middle domain
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1i5p
#=GF GA   22.00 22.00;
#=GF TC   22.00 22.30;
#=GF NC   21.90 21.40;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 90746521 -E 1000 --cpu 8 HMM pfamseq
#=GF TP   Repeat
#=GF WK   Delta_endotoxin
#=GF CL   CL0568
#=GF RN   [1]
#=GF RM   11377201
#=GF RT   Structure of Cry2Aa suggests an unexpected receptor binding
#=GF RT   epitope. 
#=GF RA   Morse RJ, Yamamoto T, Stroud RM; 
#=GF RL   Structure. 2001;9:409-417.
#=GF DR   INTERPRO; IPR015214;
#=GF DR   SCOP; 1i5p; fa;
#=GF DR   SO; 0001068; polypeptide_repeat;
#=GF CC   Members of this family adopt a structure consisting of three
#=GF CC   four-stranded beta-sheets, each with a Greek key fold, with
#=GF CC   internal pseudo threefold symmetry. Thus they act as a receptor
#=GF CC   binding beta-prism, binding to insect-specific receptors of gut
#=GF CC   epithelial cells [1].
#=GF SQ   4
#=GS M9LFB4_PAEPP/325-543  AC M9LFB4.1
#=GS V9FJ10_PHYNI/5-128    AC V9FJ10.1
#=GS M9LC08_PAEPP/455-569  AC M9LC08.1
#=GS M9LC08_PAEPP/351-448  AC M9LC08.1
M9LFB4_PAEPP/325-543             ........................LYVSTSANLYNIGDNKVNEGEYSISYWPFFNTYIQTKSNYVLSGVSGYAMRWSYTN--PFFGEYIQDHLYNIIASYVGGIQGPKIGvqlsTTELDKQikqqaragipiglddlsFNC-TLRNPITVPYFASNFQELTSSGTAGTGGFIRSDVFRSEDSM-CGLGTGY.ASAwTSYPDYYITNISATVQVDGTNTNTTPLYFGEDRAISSTHGV-----NKVIAVYNRK-a.............
V9FJ10_PHYNI/5-128               vrvqfdeseremirekqfsinvhe--------------------------------------------------------------------------------------....-------.................-QLSEVFALFYNKSAVSWCNSLSSREPLAQEQNRVLGALEARLGLRVSAEHLP.GAS.NYLADLGSQGWSGTGLTRRPQDLLQHLVVLQ--------------------------qsslaesslrqyai
M9LC08_PAEPP/455-569             .............pvdftqipinc--------------------------------------------------------------------------------------....-------.................----TLRNPLEVPYYATRFNELTSLGTAGVGGFVRSDVFISNDS-VCGLGTNYsSGQ.TFYPDYYITNISATVQVNGTNTDISPLYFGENRAITSTNGV-----NKVIAIYNRK-t.............
M9LC08_PAEPP/351-448             ........................LYVSTSANLYNIGDNKVNEGEYSISYWPFFNSYIQTRANYVLSGVSGYAIRWTYNN--PIFGRYIQDRLNNITASYIGGVNGPQIG....QQ-----.................-----------------------------------------------------.---.---------------------------------------------------------lstteldqlvqq..
#=GC seq_cons                    ..............................................................................................................................................plhs.h.s..hso.hppLoS.tshu.tt.hh.ssh.up.u..suhtp...uut.s.hsDhh.pshSuTs.sptsps.hp.Lhhhp..........................t.............
//