#=GF ID   Erp_C
#=GF AC   PF06780.16
#=GF DE   Erp protein C-terminus
#=GF PI   Erp_C-term; 
#=GF AU   Vella Briffa B;0000-0003-4380-1783
#=GF SE   Pfam-B_4561 (release 10.0)
#=GF GA   24.30 24.30;
#=GF TC   24.40 24.30;
#=GF NC   24.10 24.20;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 90746521 --cpu 8 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12616490
#=GF RT   Immune evasion of Borrelia burgdorferi: mapping of a
#=GF RT   complement-inhibitor factor H-binding site of BbCRASP-3, a novel
#=GF RT   member of the Erp protein family. 
#=GF RA   Kraiczy P, Hellwage J, Skerka C, Kirschfink M, Brade V, Zipfel
#=GF RA   PF, Wallich R; 
#=GF RL   Eur J Immunol 2003;33:697-707.
#=GF DR   INTERPRO; IPR009618;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family represents the C-terminus of bacterial Erp proteins
#=GF CC   that seem to be specific to Borrelia burgdorferi (a causative
#=GF CC   agent of Lyme disease). Borrelia Erp proteins are particularly
#=GF CC   heterogeneous, which might enable them to interact with a wide
#=GF CC   variety of host components [1].
#=GF SQ   9
#=GS A0A316HG50_9SPHI/17-144   AC A0A316HG50.1
#=GS A0A061D9Q1_BABBI/154-277  AC A0A061D9Q1.1
#=GS A0A165WYX2_9AGAM/192-319  AC A0A165WYX2.1
#=GS Q9S035_BORBU/203-342      AC Q9S035.1
#=GS H7C7R2_BORBU/229-370      AC H7C7R2.1
#=GS H7C7M1_BORBU/221-360      AC H7C7M1.1
#=GS H7C7L6_BORBU/204-344      AC H7C7L6.1
#=GS G5IXI1_BORBU/196-330      AC G5IXI1.1
#=GS A0A166LE63_9AGAM/206-333  AC A0A166LE63.1
A0A316HG50_9SPHI/17-144              tiigaeffisgckssspkvndlftqddlal-------LDEIGETILPKTSTPGAKDAQVGKFMTVMVQDCYTP.DD...qKIFTKGLND..LNDA.SDKKFGKkFLEATPQQRTELL...TDLDKEQKDYTKNKK..-----------------------------------------------pedpnhyfrm...........
A0A061D9Q1_BABBI/154-277             ...........................cse---VTKKIDAIQRSITTAKTKHEAETKEAVVKME-AVYQRFTE.AL....RAEKEQWKQ..AEKD.AVNDINS.HIKRIRDDLDEMKkskTHVASYLRQYIDNE-..LPQLKMRVA--------------------------------------sagddiaamektiaasthddl
A0A165WYX2_9AGAM/192-319             .......dgtrasasmiitaiasnvpiald------------------------------------IQKELVD.GN....KSILETAAGteLDRE.LVEQKHK.HEKELKEIREEMM...LAMKEHDEESHRELQ..MTETKLKADVQRVQTDLLKLAATLSEVIKKLEEKLQVENL-------pdaqrd...............
Q9S035_BORBU/203-342                 ..............................IKTLIAKIDEINENIDVIKWQTTVGPQGVIDRITGPVYDDFTN.GN....NSIRETWEG..LEEEsEDEGLGK.LLKELSDARDALR...TKLNEGNKPYTGYE-..EPKLKESVNVSEIKEDLEKLKSKLEEVKKYLKDSSKFEEIKGYISDS.....................
H7C7R2_BORBU/229-370                 ..............................IRTLTGKIDEINRNIDVIKEQTSVGAQGVIDRITGPVYDDFTD.GN....KAIYKTWGD..LEDD.NDEGLGK.LLKELSDTRHNLR...TKLNEGNKAYIIDTRstEPQLKENVSVSEIKSDLDELKSKLEEVKEYLEDKDNFEEIKEYVAG-s....................
H7C7M1_BORBU/221-360                 ..............................IKTLTDKIDEINKDIDGINGKTIVGAEEVIDKITGPVYDDFTD.GN....KAIYKTWGD..LEDE.EGEELGK.LLKELSDTRHNLR...TKLNEGNKAYIVLEK..EPNLKENVNVSDIQSDLEKLKSGLEEVKKYFENEDNFEEIKGYIEDS.....................
H7C7L6_BORBU/204-344                 ..............................IKKLADKIDEISWNIDGIESQTSVKPKAVIDKITGPVYDYFTD.DN...kKAIYKTWGD..LEDE.EGEGLGK.LLKELSDTRDELR...TKLNKDNKKYYAHEN..EPPLKENVDVSEIKEDLEKVKSGLEKVKEYLKDNSKFEEIKGYISYS.....................
G5IXI1_BORBU/196-330                 .............................v-QKITQNIDNITENLNSKETPKEISGKEVEEKITHPIFDHITGsGNnpgqDSISNTWGE.gLEIG.---GDSN.FFTNLEEVRSSIR...TKIKVSD-------G..TEQTKDKVEIDEIIEDLQKLKEFLEKLKKYLKDTNNLSAIEESV---kg...................
A0A166LE63_9AGAM/206-333             ...lrhdgtrasasiiitaiagnvplaldi-------------------------------------QTELVD.AN....KSILETAAGteLNRE.LVEQKHK.HEKELKEIREEMR...VAMQEHNEESQQELQ..MTETKLKADVQPMQTDLLKLAATLSEVLKKLEEKLQAEN--------lpha.................
#=GC seq_cons                        .................................lhtpIDpIscsIsshptpptstsptVhc+hThsVaDcaT-.uN....KuIhcTWus..LEc-.tsEthuK.hlKELp-sRcplR...T+lscts+tYhtppp...sphK.pVsVpclppDL.KLtutLpcVhchLc-p.phEpl............................
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