GenomeNet

Database: Pfam
Entry: Erythro-docking
LinkDB: Erythro-docking
Original site: Erythro-docking 
#=GF ID   Erythro-docking
#=GF AC   PF09277.14
#=GF DE   Erythronolide synthase, docking
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1pzq
#=GF GA   24.60 24.60;
#=GF TC   24.60 24.60;
#=GF NC   24.40 24.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12954331
#=GF RT   The structure of docking domains in modular polyketide
#=GF RT   synthases. 
#=GF RA   Broadhurst RW, Nietlispach D, Wheatcroft MP, Leadlay PF,
#=GF RA   Weissman KJ; 
#=GF RL   Chem Biol. 2003;10:723-731.
#=GF DR   INTERPRO; IPR015357;
#=GF DR   SCOP; 1pzq; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Members of this family of docking domains are found in
#=GF CC   prokaryotic erythronolide synthase. They adopt a structure
#=GF CC   consisting of a bundle of four alpha-helices, and mediate
#=GF CC   homodimerisation of the protein, stabilising the resulting
#=GF CC   complex [1].
#=GF SQ   29
#=GS H2JPR6_STRHJ/1763-1815      AC H2JPR6.1
#=GS A0A1Q5GIQ8_9ACTN/1868-1914  AC A0A1Q5GIQ8.1
#=GS M3BYW5_STRMB/1218-1277      AC M3BYW5.1
#=GS A0A0F0HIL7_9PSEU/1750-1799  AC A0A0F0HIL7.1
#=GS A0A6G2VJI4_9ACTN/112-163    AC A0A6G2VJI4.1
#=GS A0A561UQ39_9ACTN/1728-1774  AC A0A561UQ39.1
#=GS A0A0B5EP70_STRA4/3295-3349  AC A0A0B5EP70.1
#=GS A0A6F7W5K9_9ACTN/92-152     AC A0A6F7W5K9.1
#=GS A0A1V2RCB5_9ACTN/563-618    AC A0A1V2RCB5.1
#=GS A0A372P9D0_9ACTN/150-201    AC A0A372P9D0.1
#=GS A4F7P0_SACEN/3490-3547      AC A4F7P0.1
#=GS A0A2V4N3V6_9ACTN/1-59       AC A0A2V4N3V6.1
#=GS A0A0F0HH81_9PSEU/451-507    AC A0A0F0HH81.1
#=GS A0A4P6UCF9_9NOCA/3525-3581  AC A0A4P6UCF9.1
#=GS D5ZU00_STRV1/129-185        AC D5ZU00.1
#=GS A0A6H0CIY9_9ACTN/1740-1794  AC A0A6H0CIY9.1
#=GS V6L516_STRRC/93-143         AC V6L516.1
#=GS S3B9T2_9ACTN/2268-2321      AC S3B9T2.1
#=GS A0A286EAV7_9ACTN/223-281    AC A0A286EAV7.1
#=GS A0A4R4XWS4_9ACTN/3387-3438  AC A0A4R4XWS4.1
#=GS A0A117Q5E5_9ACTN/1740-1789  AC A0A117Q5E5.1
#=GS A0A5Q4SV38_9ACTN/1738-1788  AC A0A5Q4SV38.1
#=GS A0A4Q7KHF7_9PSEU/3329-3381  AC A0A4Q7KHF7.1
#=GS A0A286EAE2_9ACTN/2531-2586  AC A0A286EAE2.1
#=GS A0A504CD11_9RHIZ/1736-1785  AC A0A504CD11.1
#=GS A0A3G2JK27_9ACTN/1780-1831  AC A0A3G2JK27.1
#=GS A0A291Q3Y1_9ACTN/4591-4648  AC A0A291Q3Y1.1
#=GS A0A345I2F4_9ACTN/205-258    AC A0A345I2F4.1
#=GS G2NJK5_STREK/1736-1782      AC G2NJK5.1
H2JPR6_STRHJ/1763-1815                 .......sal---------AELDRLEAAL.H.A...L.PD.QDG....sH.AR.VTARLEALLRGWQDS..HARPTGP------aspadv......
A0A1Q5GIQ8_9ACTN/1868-1914             ......sala----------DLDRLEAAL.L.A...L.PD.RDG....sH.TR.VTARLEALLRGWYDA..R------------dthgrd......
M3BYW5_STRMB/1218-1277                 .....qgpgr------SLTDRIDDLEAAL.L.A...A.AG.GDGvpdreH.AD.VAARLDSLLRRWRDE..RGEEPRA------daht........
A0A0F0HIL7_9PSEU/1750-1799             .....rlmva----------EVDRLEAAL.T.A...L.PD.QDG....sH.AR.ITARLEALLRTWRD-..-------------thgsagaaea..
A0A6G2VJI4_9ACTN/112-163               ......sala----------EVDRLEAAL.H.A...L.PD.QDG....sH.TR.VTARLEALLRSWQDA..HGRHSE-------pesped......
A0A561UQ39_9ACTN/1728-1774             ......llva----------EVDRLETAL.A.A...V.AD.QDG....sH.AR.ITARLEALLRTWR--..-------------dahgtggta...
A0A0B5EP70_STRA4/3295-3349             .....deaaa-------VLADLDRLESAL.T.A...L.PA.EDG.....R.RDrIGARLRSLLTRWQD-..-------------gerggagaepaq
A0A6F7W5K9_9ACTN/92-152                ..atavtsll---------AELDGLEKSL.SgA...T.PD.DEG.....R.SR.ITARLQALLAQWNDD..RGPED--------gagvaeelesa.
A0A1V2RCB5_9ACTN/563-618               ..saakpvlg----------QLAELEAAL.G.A...LePD.EST.....R.ED.VAKRLQNLLWRWNES..ASPAPSS------gvdgd.......
A0A372P9D0_9ACTN/150-201               ......sasp-------VFAELDALETAL.E.NcdvM.GD.ESG.....-.-R.ITARLEALLRRWQDS..R------------vmggiaat....
A4F7P0_SACEN/3490-3547                 ..........AASPAVDIGDRLDELEKAL.E.A...L.SA.EDG.....H.DD.VGQRLESLLRRWNSR..RADAPSTSAISED............
A0A2V4N3V6_9ACTN/1-59                  gadpsapllg----------EVDRLDAAL.A.A...F.AP.TGG.....AaAK.ITARLEALLRKWQDL..QATDHDTDT----eadl........
A0A0F0HH81_9PSEU/451-507               ...adavvpl--------LAELDRLEAALaD.T...A.PD.DEG.....H.LR.VANRLQSLLAKWNDQ..QVPAENA------avaee.......
A0A4P6UCF9_9NOCA/3525-3581             .....stssk------GIDDRLDELDRAL.E.A...L.PE.DER.....D.ED.IANRLESMLRRWNAK..RAPGPDAPVIDDD............
D5ZU00_STRV1/129-185                   ....epdpva------PVLAELDRLERAL.G.R...L.PV.V--.....-.DE.ISTRLHTLLRRWDER..SAPAEA-------galssasad...
A0A6H0CIY9_9ACTN/1740-1794             .......sal---------AELDRLEATL.H.A...L.PD.QDG....sH.AR.VTARLEALLRDWQDThgRPAAPGT------padvgd......
V6L516_STRRC/93-143                    ........al---------AELDRLETAL.H.G...L.PD.QDG....sH.AR.VTARLEALLRSWQDThgRHPAPE-------apad........
S3B9T2_9ACTN/2268-2321                 ...aepegdg------GLEEALDRLEERL.A.A...A.PE.ETA.....H.DQ.VAARLRSLARRWEER..RGPAG--------dge.........
A0A286EAV7_9ACTN/223-281               ..aapadhgr------EVRAGLDRLEAAL.E.A...L.PR.EDG.....ArDE.AGTRLRSLLARLGGT..GADAPAA------tgst........
A0A4R4XWS4_9ACTN/3387-3438             .......pvl---------AEVDRLEAAL.S.A...A.AA.AGG....dH.TR.ITARLEALLRSWQDR..EDGGTEP------epdsg.......
A0A117Q5E5_9ACTN/1740-1789             ........al---------AELDRLEATL.H.D...L.PD.QDG....sH.AR.VTARLEALLRSWQDT..-------------hgrhsapgape.
A0A5Q4SV38_9ACTN/1738-1788             ......alad-----------VDRLEAVL.L.G...L.PD.EDG....sH.TR.VTARLEALLRGWQDA..RGGDAAP------apaqd.......
A0A4Q7KHF7_9PSEU/3329-3381             ........gd---PAQPVLAEVDRLESAL.A.A...A.TD.LNG....dH.AR.VTARLEALLRRWRDQ..-------------etqgndga....
A0A286EAE2_9ACTN/2531-2586             ....apsldt----------ELDRLESAL.S.L...LtPD.DTR.....H.AD.IGARLRALLSRWDEThsRTEAADT------gtdar.......
A0A504CD11_9RHIZ/1736-1785             .......lad-----------VDRLEAVL.L.G...L.PD.EDG....sH.TR.VTARLEALLRGWQDA..RGGDAAP------apaqd.......
A0A3G2JK27_9ACTN/1780-1831             .......tal---------AELDRLEAAL.L.T...L.PD.EGG....sH.AR.VTARLEALLRSWQDT..HGRHPAPVA----ped.........
A0A291Q3Y1_9ACTN/4591-4648             ........qg---PAVTVAAEIDRLAAAL.A.A...G.PSgPEE.....H.AE.VGARLAELLRSWQSG..GAADDDLSSATDD............
A0A345I2F4_9ACTN/205-258               ........pg---PESGVLDQLDRLESAL.R.T...L.PD.DGT.....A.TK.VDLRLRALLARWGEA..RAGAV--------dedsg.......
G2NJK5_STREK/1736-1782                 .......lad-----------VDRVEAAL.L.A...L.PD.EDG....sH.AR.VTARLEALLRGWQDA..RDAAPES------pq..........
#=GC seq_cons                          ........st.........s-LDRLEuAL.t.A...L.PD.p-G.....H.s+.VoARLEALLRpWpDp..cs.sst.......sstst.......
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