GenomeNet

Database: Pfam
Entry: Frizzled
LinkDB: Frizzled
Original site: Frizzled 
#=GF ID   Frizzled
#=GF AC   PF01534.19
#=GF DE   Frizzled/Smoothened family membrane region
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_949 (release 4.0)
#=GF GA   22.30 22.30;
#=GF TC   22.30 22.30;
#=GF NC   22.20 22.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Frizzled
#=GF CL   CL0192
#=GF RN   [1]
#=GF RM   8717036
#=GF RT   A new member of the frizzled family from Drosophila functions as
#=GF RT   a Wingless receptor. 
#=GF RA   Bhanot P, Brink M, Samos CH, Hsieh JC, Wang Y, Macke JP, Andrew
#=GF RA   D, Nathans J, Nusse R; 
#=GF RL   Nature 1996;382:225-230.
#=GF RN   [2]
#=GF RM   15239825
#=GF RT   The Frizzled family: receptors for multiple signal transduction
#=GF RT   pathways. 
#=GF RA   Huang HC, Klein PS; 
#=GF RL   Genome Biol 2004;5:234.
#=GF RN   [3]
#=GF RM   9811578
#=GF RT   In vivo evidence that Patched and Smoothened constitute distinct
#=GF RT   binding and transducing components of a Hedgehog receptor
#=GF RT   complex. 
#=GF RA   Chen Y, Struhl G; 
#=GF RL   Development 1998;125:4943-4948.
#=GF RN   [4]
#=GF RM   9852758
#=GF RT   The frizzled motif: in how many different protein families does
#=GF RT   it occur?. 
#=GF RA   Rehn M, Pihlajaniemi T, Hofmann K, Bucher P; 
#=GF RL   Trends Biochem Sci 1998;23:415-417.
#=GF DR   INTERPRO; IPR000539;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family contains the membrane spanning region of frizzled
#=GF CC   and smoothened receptors.  This membrane region is predicted to
#=GF CC   contain seven transmembrane alpha helices.  Proteins related to
#=GF CC   Drosophila frizzled (Swiss:P18537) are receptors for Wnt
#=GF CC   (mediating the beta-catenin signalling pathway) [1], but also
#=GF CC   the planar cell polarity (PCP) pathway and the Wnt/calcium
#=GF CC   pathway. The predominantly alpha-helical Cys-rich ligand-binding
#=GF CC   region (CRD) of Frizzled is both necessary and sufficient for
#=GF CC   Wnt binding [2].  The smoothened receptor mediates hedgehog
#=GF CC   signalling [3].
#=GF SQ   3979
#=GS A0A2Y9HSI3_NEOSC/193-514    AC A0A2Y9HSI3.1
#=GS A0A673ZRB5_SALTR/217-537    AC A0A673ZRB5.1
#=GS A0A3P8X8B4_ESOLU/210-531    AC A0A3P8X8B4.1
#=GS A0A0D8XCF5_DICVI/137-182    AC A0A0D8XCF5.1
#=GS A0A3L8S6X3_CHLGU/220-540    AC A0A3L8S6X3.1
#=GS K7JBY1_NASVI/265-566        AC K7JBY1.1
#=GS H3D2B1_TETNG/221-539        AC H3D2B1.1
#=GS A0A0Q3MFS2_AMAAE/1-217      AC A0A0Q3MFS2.1
#=GS A0A067QI70_ZOONE/205-525    AC A0A067QI70.1
#=GS U3I631_ANAPP/131-452        AC U3I631.2
#=GS A0A3Q1JX34_ANATE/187-507    AC A0A3Q1JX34.1
#=GS L5L2J7_PTEAL/193-514        AC L5L2J7.1
#=GS A0A3Q3L3F5_9TELE/223-542    AC A0A3Q3L3F5.1
#=GS A0A3Q4GZ57_NEOBR/183-505    AC A0A3Q4GZ57.1
#=GS A0A0C2BYQ8_9BILA/125-220    AC A0A0C2BYQ8.1
#=GS A0A2K6FNR2_PROCO/189-510    AC A0A2K6FNR2.1
#=GS W2YVJ0_PHYPR/3-133          AC W2YVJ0.1
#=GS A0A2Y9PX74_DELLE/210-511    AC A0A2Y9PX74.1
#=GS A0A452QBX7_URSAM/233-553    AC A0A452QBX7.1
#=GS A0A2T7Q003_POMCA/254-584    AC A0A2T7Q003.1
#=GS L9L0V5_TUPCH/468-788        AC L9L0V5.1
#=GS A0A4W5Q2A1_9TELE/197-528    AC A0A4W5Q2A1.1
#=GS W5P216_SHEEP/212-513        AC W5P216.1
#=GS A0A158PD58_ANGCS/165-365    AC A0A158PD58.1
#=GS A0A670J6C8_PODMU/260-581    AC A0A670J6C8.1
#=GS FZD2_HUMAN/235-555          AC Q14332.1
#=GS A0A452SU46_URSAM/197-524    AC A0A452SU46.1
#=GS Q9W6E3_DANRE/218-537        AC Q9W6E3.1
#=GS L8H7H3_ACACA/196-514        AC L8H7H3.1
#=GS B0S6S2_DANRE/222-532        AC B0S6S2.1
#=GS A0A3B0J8D1_DROGU/266-565    AC A0A3B0J8D1.1
#=GS A0A0V1H0Z7_9BILA/229-521    AC A0A0V1H0Z7.1
#=GS A0A099YTL2_TINGU/101-421    AC A0A099YTL2.1
#=GS A0A3L8S406_CHLGU/47-315     AC A0A3L8S406.1
#=GS F1SSU5_PIG/226-537          AC F1SSU5.1
#=GS A0A6A5EVP2_PERFL/212-532    AC A0A6A5EVP2.1
#=GS A0A6A4K946_APOLU/249-575    AC A0A6A4K946.1
#=GS A3QK10_DANRE/217-537        AC A3QK10.1
#=GS A0A2Y9MML7_DELLE/226-537    AC A0A2Y9MML7.1
#=GS F6QL95_MACMU/193-514        AC F6QL95.1
#=GS A0A3Q0KQD7_SCHMA/509-805    AC A0A3Q0KQD7.1
#=GS A0A2I3TGC6_PANTR/244-564    AC A0A2I3TGC6.1
#=GS A0A093PNA1_9PASS/195-515    AC A0A093PNA1.1
#=GS A0A5N3UKB8_MUNRE/352-409    AC A0A5N3UKB8.1
#=GS M7BT84_CHEMY/2-326          AC M7BT84.1
#=GS FZD6_HUMAN/189-510          AC O60353.2
#=GS A0A667XVS5_9TELE/207-528    AC A0A667XVS5.1
#=GS A0A6G0HLF3_LARCR/230-541    AC A0A6G0HLF3.1
#=GS A0A5N3UJW5_MUNRE/95-299     AC A0A5N3UJW5.1
#=GS G5C1T1_HETGA/236-575        AC G5C1T1.1
#=GS A0A1U7QEK4_MESAU/271-591    AC A0A1U7QEK4.1
#=GS E2AEJ0_CAMFO/438-565        AC E2AEJ0.1
#=GS A0A0N4WGB6_HAEPC/209-518    AC A0A0N4WGB6.2
#=GS A0A0L0HTC9_SPIPD/74-278     AC A0A0L0HTC9.1
#=GS FZD6_CHICK/77-190           AC Q9PTW1.1
#=GS A0A087VY56_ECHMU/499-602    AC A0A087VY56.1
#=GS A0A0G2JYI3_RAT/91-422       AC A0A0G2JYI3.1
#=GS A0A093H3I6_DRYPU/179-500    AC A0A093H3I6.1
#=GS A7RSX2_NEMVE/95-363         AC A7RSX2.1
#=GS F4WXL7_ACREC/187-442        AC F4WXL7.1
#=GS A0A091RCH5_9GRUI/201-521    AC A0A091RCH5.1
#=GS A0A315V8F3_GAMAF/220-540    AC A0A315V8F3.1
#=GS G1SWP7_RABIT/189-510        AC G1SWP7.2
#=GS A0A0V1AZU1_TRISP/276-607    AC A0A0V1AZU1.1
#=GS A0A2Y9GXK6_NEOSC/323-370    AC A0A2Y9GXK6.1
#=GS A0A0V0TYP0_9BILA/201-421    AC A0A0V0TYP0.1
#=GS A0A504Y2R6_FASGI/185-411    AC A0A504Y2R6.1
#=GS B7P2S7_IXOSC/224-520        AC B7P2S7.1
#=GS A0A401SQH6_CHIPU/230-551    AC A0A401SQH6.1
#=GS B0WLH4_CULQU/21-201         AC B0WLH4.1
#=GS A0A0V1D425_TRIBR/329-549    AC A0A0V1D425.1
#=GS FZD2_RAT/240-560            AC Q08464.1
#=GS A0A0R3SBC6_HYMDI/248-588    AC A0A0R3SBC6.1
#=GS A0A0C2F347_9BILA/32-165     AC A0A0C2F347.1
#=GS F0ZQZ2_DICPU/229-530        AC F0ZQZ2.1
#=GS A0A6I8RXK0_XENTR/119-450    AC A0A6I8RXK0.1
#=GS A0A6A3P3M2_9STRA/167-330    AC A0A6A3P3M2.1
#=GS A0A662YLP7_ACIRT/404-497    AC A0A662YLP7.1
#=GS I3IU79_ORENI/185-505        AC I3IU79.2
#=GS F1PWM8_CANLF/218-538        AC F1PWM8.2
#=GS A0A091SMK7_PELCR/28-348     AC A0A091SMK7.1
#=GS A0A2Y9DAH4_TRIMA/188-509    AC A0A2Y9DAH4.1
#=GS A0A226MLG2_CALSU/219-539    AC A0A226MLG2.1
#=GS A0A060Y296_ONCMY/7-266      AC A0A060Y296.1
#=GS A0A5F4BXY4_CANLF/214-515    AC A0A5F4BXY4.1
#=GS A0A4W4DMI4_ELEEL/233-543    AC A0A4W4DMI4.1
#=GS G3RNY6_GORGO/193-514        AC G3RNY6.1
#=GS A0A093DZ70_TAUER/201-521    AC A0A093DZ70.1
#=GS A0A4U5PG49_STECR/203-407    AC A0A4U5PG49.1
#=GS G1NQQ0_MELGA/121-422        AC G1NQQ0.2
#=GS A0A2U3XT46_LEPWE/244-564    AC A0A2U3XT46.1
#=GS A0A3R7H6M7_CLOSI/690-880    AC A0A3R7H6M7.1
#=GS A0A0N4VM29_ENTVE/204-533    AC A0A0N4VM29.1
#=GS A0A3B5KG25_TAKRU/228-548    AC A0A3B5KG25.2
#=GS L5K2C3_PTEAL/414-515        AC L5K2C3.1
#=GS A0A4W3HAZ5_CALMI/227-547    AC A0A4W3HAZ5.1
#=GS H2MMR4_ORYLA/205-526        AC H2MMR4.2
#=GS G4Z132_PHYSP/191-354        AC G4Z132.1
#=GS A0A315VM28_GAMAF/227-538    AC A0A315VM28.1
#=GS H2YUA8_CIOSA/186-499        AC H2YUA8.1
#=GS W4Z465_STRPU/222-527        AC W4Z465.1
#=GS A0A0R3X1U4_HYDTA/253-592    AC A0A0R3X1U4.1
#=GS L8HWH3_9CETA/185-505        AC L8HWH3.1
#=GS A3KMX5_BOVIN/218-538        AC A3KMX5.1
#=GS A0A4W6FWI7_LATCA/264-585    AC A0A4W6FWI7.1
#=GS A0A2R8MXI9_CALJA/235-555    AC A0A2R8MXI9.2
#=GS A0A060VNE3_ONCMY/226-430    AC A0A060VNE3.1
#=GS A0A4X2LW28_VOMUR/236-563    AC A0A4X2LW28.1
#=GS A0A643BWN7_BALPH/1-54       AC A0A643BWN7.1
#=GS A0A2K5C949_AOTNA/216-517    AC A0A2K5C949.1
#=GS A0A672YSS7_9TELE/200-493    AC A0A672YSS7.1
#=GS A0A673BSG3_9TELE/199-500    AC A0A673BSG3.1
#=GS U3KIN2_FICAL/176-496        AC U3KIN2.1
#=GS A0A3B0JS84_DROGU/313-625    AC A0A3B0JS84.1
#=GS A0A0V0VKV1_9BILA/240-567    AC A0A0V0VKV1.1
#=GS A0A3Q2GMS5_CYPVA/219-538    AC A0A3Q2GMS5.1
#=GS A0A2U9CCF7_SCOMX/226-544    AC A0A2U9CCF7.1
#=GS A0A2I4BMM6_9TELE/229-540    AC A0A2I4BMM6.1
#=GS G1SAN4_NOMLE/222-544        AC G1SAN4.1
#=GS FZD1_RAT/304-631            AC Q08463.1
#=GS A0A182HBQ8_AEDAL/14-185     AC A0A182HBQ8.1
#=GS A0A5F4C8L0_CANLF/193-514    AC A0A5F4C8L0.1
#=GS A0A1I7VXY0_LOALO/173-378    AC A0A1I7VXY0.1
#=GS A0A0L7LSB0_9NEOP/27-195     AC A0A0L7LSB0.1
#=GS A0A5G2RCM0_PIG/189-509      AC A0A5G2RCM0.1
#=GS A0A2K5KJX2_CERAT/244-564    AC A0A2K5KJX2.1
#=GS A0A0K0DW05_STRER/210-470    AC A0A0K0DW05.1
#=GS A0A2Y9N1H2_DELLE/244-564    AC A0A2Y9N1H2.1
#=GS A0A194RLP0_PAPMA/1074-1400  AC A0A194RLP0.1
#=GS A0A3P7JAF4_ANGCS/162-472    AC A0A3P7JAF4.1
#=GS A0A195D3P5_9HYME/225-549    AC A0A195D3P5.1
#=GS S4RMN9_PETMA/41-357         AC S4RMN9.1
#=GS A0A3Q0KT77_SCHMA/196-559    AC A0A3Q0KT77.1
#=GS J9HZD2_AEDAE/1-110          AC J9HZD2.1
#=GS A0A3P9PPB2_POERE/186-506    AC A0A3P9PPB2.1
#=GS A0A6A4VPS0_AMPAM/1-171      AC A0A6A4VPS0.1
#=GS A0A218UX76_9PASE/226-545    AC A0A218UX76.1
#=GS F4WXL7_ACREC/448-574        AC F4WXL7.1
#=GS A0A2U9BCT3_SCOMX/251-572    AC A0A2U9BCT3.1
#=GS A0A1S3SAH1_SALSA/264-585    AC A0A1S3SAH1.1
#=GS A0A060XXC0_ONCMY/114-435    AC A0A060XXC0.1
#=GS A0A195CPR7_9HYME/188-437    AC A0A195CPR7.1
#=GS A0A2K5X653_MACFA/232-555    AC A0A2K5X653.1
#=GS A0A4E0RXJ8_FASHE/336-598    AC A0A4E0RXJ8.1
#=GS T1J7J7_STRMM/218-518        AC T1J7J7.1
#=GS A0A0L7QT69_9HYME/280-581    AC A0A0L7QT69.1
#=GS W2SKD3_NECAM/141-347        AC W2SKD3.1
#=GS A0A2U3WX61_ODORO/210-511    AC A0A2U3WX61.1
#=GS E3MFM0_CAERE/327-541        AC E3MFM0.1
#=GS A0A3Q4B9V8_MOLML/190-500    AC A0A3Q4B9V8.1
#=GS A0A4W5KAJ4_9TELE/227-539    AC A0A4W5KAJ4.1
#=GS B3MUK2_DROAN/235-559        AC B3MUK2.2
#=GS B4GJP7_DROPE/240-564        AC B4GJP7.1
#=GS A0A2K6Q6X4_RHIRO/241-561    AC A0A2K6Q6X4.1
#=GS A0A0V0TL07_9BILA/211-535    AC A0A0V0TL07.1
#=GS S7N762_MYOBR/126-447        AC S7N762.1
#=GS A0A0V0RV26_9BILA/336-556    AC A0A0V0RV26.1
#=GS E2R9M9_CANLF/193-514        AC E2R9M9.1
#=GS A0A452QYK1_URSAM/210-511    AC A0A452QYK1.1
#=GS A0A498SPG4_ACAVI/210-542    AC A0A498SPG4.1
#=GS FZD5_HUMAN/226-537          AC Q13467.2
#=GS A0A151NM52_ALLMI/159-436    AC A0A151NM52.1
#=GS A0A444UJD5_ACIRT/195-517    AC A0A444UJD5.1
#=GS A0A5N5JTH1_PANHP/209-529    AC A0A5N5JTH1.1
#=GS A0A1V4JVL3_PATFA/190-509    AC A0A1V4JVL3.1
#=GS C3YX49_BRAFL/183-481        AC C3YX49.1
#=GS A0A3Q4AB92_MOLML/229-550    AC A0A3Q4AB92.1
#=GS A0A3P8TJE3_AMPPE/201-502    AC A0A3P8TJE3.1
#=GS A0A3Q3EAZ4_9LABR/211-531    AC A0A3Q3EAZ4.1
#=GS A0A0V0WIA0_9BILA/327-547    AC A0A0V0WIA0.1
#=GS A0A3Q2VWN5_HAPBU/221-540    AC A0A3Q2VWN5.1
#=GS A0A3Q0KQD7_SCHMA/397-497    AC A0A3Q0KQD7.1
#=GS A0A2Y9GXB6_NEOSC/180-501    AC A0A2Y9GXB6.1
#=GS A0A444UHE5_ACIRT/194-471    AC A0A444UHE5.1
#=GS C3ZTW1_BRAFL/148-395        AC C3ZTW1.1
#=GS D6WG76_TRICA/231-540        AC D6WG76.1
#=GS G3TV59_LOXAF/226-537        AC G3TV59.1
#=GS A0A556TJL1_BAGYA/229-364    AC A0A556TJL1.1
#=GS A0A2K6S5M8_SAIBB/244-564    AC A0A2K6S5M8.1
#=GS G5B526_HETGA/159-460        AC G5B526.1
#=GS A0A5C6P2Q7_9TELE/230-540    AC A0A5C6P2Q7.1
#=GS A0A093R714_PYGAD/28-348     AC A0A093R714.1
#=GS A0A3Q3BHQ9_HAPBU/212-523    AC A0A3Q3BHQ9.1
#=GS A0A183P3W7_9TREM/358-614    AC A0A183P3W7.1
#=GS A0A5N5TDS7_9CRUS/287-456    AC A0A5N5TDS7.1
#=GS V8N6J5_OPHHA/222-542        AC V8N6J5.1
#=GS A0A673VVH0_SALTR/207-528    AC A0A673VVH0.1
#=GS A0A2I0LNP7_COLLI/312-628    AC A0A2I0LNP7.1
#=GS A0A452G959_CAPHI/244-596    AC A0A452G959.1
#=GS A0A3Q2UK00_CHICK/190-511    AC A0A3Q2UK00.1
#=GS A0A3S2MCV8_ORYJA/195-496    AC A0A3S2MCV8.1
#=GS A0A3B1IYG1_ASTMX/206-537    AC A0A3B1IYG1.1
#=GS A0A402EDB5_9SAUR/193-375    AC A0A402EDB5.1
#=GS A0A674P0D6_TAKRU/196-302    AC A0A674P0D6.1
#=GS A0A6A4VNF5_AMPAM/206-542    AC A0A6A4VNF5.1
#=GS A0A3Q2CUS8_CYPVA/191-522    AC A0A3Q2CUS8.1
#=GS A0A0V0WTL2_TRIPS/44-98      AC A0A0V0WTL2.1
#=GS A0A674PKY2_TAKRU/221-506    AC A0A674PKY2.1
#=GS A0A0R3U7D6_9CEST/193-563    AC A0A0R3U7D6.1
#=GS FRIZ2_DROME/308-620         AC Q9VVX3.1
#=GS A0A674ANG1_SALTR/207-526    AC A0A674ANG1.1
#=GS A0A2A4K5Z6_HELVI/134-441    AC A0A2A4K5Z6.1
#=GS A0A026WRU5_OOCBI/233-568    AC A0A026WRU5.1
#=GS B4MWJ5_DROWI/244-568        AC B4MWJ5.1
#=GS H2P8B3_PONAB/244-564        AC H2P8B3.1
#=GS A0A3B5K6S3_TAKRU/212-532    AC A0A3B5K6S3.2
#=GS A0A5E4D1S7_MARMO/210-511    AC A0A5E4D1S7.1
#=GS A0A5E4R373_9NEOP/188-487    AC A0A5E4R373.1
#=GS A0A5N5M7B0_PANHP/236-463    AC A0A5N5M7B0.1
#=GS A0A1S4FJE8_AEDAE/196-502    AC A0A1S4FJE8.1
#=GS A0A674DGA3_SALTR/200-531    AC A0A674DGA3.1
#=GS A0A4D9DXI3_9SAUR/196-527    AC A0A4D9DXI3.1
#=GS A0A665U4F1_ECHNA/222-542    AC A0A665U4F1.1
#=GS A0A067RTB7_ZOONE/92-419     AC A0A067RTB7.1
#=GS A0A0Q3R5T4_AMAAE/175-498    AC A0A0Q3R5T4.1
#=GS A0A0L8HAJ2_OCTBM/207-512    AC A0A0L8HAJ2.1
#=GS A0A093QRK8_9PASS/2-219      AC A0A093QRK8.1
#=GS A0A1S3EVT0_DIPOR/189-510    AC A0A1S3EVT0.1
#=GS A0A225VG01_9STRA/3-256      AC A0A225VG01.1
#=GS A0A2K6UB34_SAIBB/193-514    AC A0A2K6UB34.1
#=GS A0A3Q7UHI6_URSAR/226-537    AC A0A3Q7UHI6.1
#=GS A4V438_DROME/374-559        AC A4V438.1
#=GS A0A3P7FRX4_WUCBA/57-298     AC A0A3P7FRX4.1
#=GS A0A183CUE3_9BILA/129-182    AC A0A183CUE3.1
#=GS A0A4W2HVW0_BOBOX/210-511    AC A0A4W2HVW0.1
#=GS A0A5N5T395_9CRUS/3-174      AC A0A5N5T395.1
#=GS A0A2K5WG81_MACFA/159-460    AC A0A2K5WG81.1
#=GS A0A4W4GP95_ELEEL/215-535    AC A0A4W4GP95.1
#=GS A0A3P8SLM5_AMPPE/221-541    AC A0A3P8SLM5.1
#=GS A0A183MNT9_9TREM/238-643    AC A0A183MNT9.1
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#=GS M4ATD6_XIPMA/172-493        AC M4ATD6.2
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#=GS A0A4W4DMU5_ELEEL/218-541    AC A0A4W4DMU5.1
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#=GS A0A4W5KAI4_9TELE/205-506    AC A0A4W5KAI4.1
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#=GS A0A091V370_NIPNI/174-494    AC A0A091V370.1
#=GS M4A8M0_XIPMA/196-517        AC M4A8M0.1
#=GS A0A2A3EBH9_APICC/227-562    AC A0A2A3EBH9.1
#=GS A0A3B0K8N5_DROGU/240-564    AC A0A3B0K8N5.1
#=GS A0A267GCT1_9PLAT/266-575    AC A0A267GCT1.1
#=GS A0A673A0E6_9TELE/179-510    AC A0A673A0E6.1
#=GS W5JE26_ANODA/1-169          AC W5JE26.1
#=GS E2BJ61_HARSA/314-631        AC E2BJ61.1
#=GS A0A0V1PHN0_9BILA/324-544    AC A0A0V1PHN0.1
#=GS A0A2R9ALJ4_PANPA/205-536    AC A0A2R9ALJ4.1
#=GS A0A3P6QF43_DIBLA/18-294     AC A0A3P6QF43.1
#=GS A0A2P4S8X6_BAMTH/238-557    AC A0A2P4S8X6.1
#=GS A0A091KA58_COLST/130-450    AC A0A091KA58.1
#=GS E9GI97_DAPPU/225-556        AC E9GI97.1
#=GS T1FXD5_HELRO/220-556        AC T1FXD5.1
#=GS A0A1J1HJ86_9DIPT/270-583    AC A0A1J1HJ86.1
#=GS A0A091UXV7_NIPNI/192-511    AC A0A091UXV7.1
#=GS A0A2K5KK34_CERAT/222-544    AC A0A2K5KK34.1
#=GS A0A498LYH5_LABRO/234-544    AC A0A498LYH5.1
#=GS Q6NV44_DANRE/229-549        AC Q6NV44.2
#=GS A0A1L8GTP2_XENLA/194-525    AC A0A1L8GTP2.1
#=GS A0A1L8GTP2_XENLA/194-525    DR PDB; 6D35 A; 194-525;
#=GS A0A1L8GTP2_XENLA/194-525    DR PDB; 6D32 A; 194-525;
#=GS A0A1S3SAF8_SALSA/264-585    AC A0A1S3SAF8.1
#=GS A0A4W4G3N4_ELEEL/191-511    AC A0A4W4G3N4.1
#=GS A0A4W2CGE1_BOBOX/244-564    AC A0A4W2CGE1.1
#=GS A0A2A4JYU1_HELVI/129-335    AC A0A2A4JYU1.1
#=GS A0A2K5C6T9_AOTNA/224-555    AC A0A2K5C6T9.1
#=GS A0A4W2D314_BOBOX/226-537    AC A0A4W2D314.1
#=GS H0XM62_OTOGA/193-514        AC H0XM62.1
#=GS H2Y559_CIOSA/167-425        AC H2Y559.1
#=GS I3MGL6_ICTTR/193-514        AC I3MGL6.2
#=GS A0A2Y9NPM0_DELLE/221-552    AC A0A2Y9NPM0.1
#=GS A0A4W5LZ10_9TELE/160-429    AC A0A4W5LZ10.1
#=GS A8JUT5_DROME/291-587        AC A8JUT5.1
#=GS A0A2Y9DHD2_TRIMA/236-556    AC A0A2Y9DHD2.1
#=GS A0A2I0MQC6_COLLI/109-382    AC A0A2I0MQC6.1
#=GS A0A3Q7RVV0_VULVU/189-510    AC A0A3Q7RVV0.1
#=GS A0A673BSR5_9TELE/203-522    AC A0A673BSR5.1
#=GS A0A668A8C9_9TELE/231-541    AC A0A668A8C9.1
#=GS A0A482VXB5_9CUCU/213-541    AC A0A482VXB5.1
#=GS A0A3Q1MCH2_BOVIN/203-500    AC A0A3Q1MCH2.1
#=GS A0A2A2J4M4_9BILA/211-427    AC A0A2A2J4M4.1
#=GS H9JH88_BOMMO/40-367         AC H9JH88.1
#=GS A0A5J5CGT0_9PERO/230-541    AC A0A5J5CGT0.1
#=GS A0A3Q4HA28_NEOBR/230-541    AC A0A3Q4HA28.1
#=GS A0A668AJ03_9TELE/199-530    AC A0A668AJ03.1
#=GS A0A6H5IXB0_9HYME/309-439    AC A0A6H5IXB0.1
#=GS A0A091PRM4_HALAL/155-475    AC A0A091PRM4.1
#=GS A0A183TKR6_SCHSO/34-120     AC A0A183TKR6.1
#=GS A0A1S3FSY8_DIPOR/193-514    AC A0A1S3FSY8.1
#=GS A0A4C1UPH5_EUMVA/13-88      AC A0A4C1UPH5.1
#=GS A0A0K0EZK3_STRVS/222-538    AC A0A0K0EZK3.1
#=GS A0A091KGI0_9GRUI/130-451    AC A0A091KGI0.1
#=GS A0A093G285_DRYPU/228-547    AC A0A093G285.1
#=GS A0A2I4CTD0_9TELE/205-522    AC A0A2I4CTD0.1
#=GS A0A667ZZR5_9TELE/213-514    AC A0A667ZZR5.1
#=GS A0A3P6ZQU1_HYMDI/97-210     AC A0A3P6ZQU1.1
#=GS A0A5N3UHR5_MUNRE/31-383     AC A0A5N3UHR5.1
#=GS A0A2K5LPQ1_CERAT/189-510    AC A0A2K5LPQ1.1
#=GS A0A3L8Q5P4_CHLGU/226-534    AC A0A3L8Q5P4.1
#=GS A0A091KDN6_9GRUI/119-420    AC A0A091KDN6.1
#=GS F6SH04_XENTR/223-543        AC F6SH04.3
#=GS I3NEG7_ICTTR/226-546        AC I3NEG7.2
#=GS H2Y9A3_CIOSA/198-514        AC H2Y9A3.1
#=GS A0A183NTJ0_9TREM/601-805    AC A0A183NTJ0.1
#=GS G1NN05_MELGA/193-513        AC G1NN05.1
#=GS A0A2K5LNM3_CERAT/263-527    AC A0A2K5LNM3.1
#=GS A0A093GAD9_DRYPU/55-386     AC A0A093GAD9.1
#=GS A0A2A2L587_9BILA/205-377    AC A0A2A2L587.1
#=GS F7A3X8_ORNAN/200-531        AC F7A3X8.2
#=GS A0A3Q1GCQ3_9TELE/201-502    AC A0A3Q1GCQ3.1
#=GS F6QFJ6_MACMU/189-510        AC F6QFJ6.3
#=GS A0A340WH02_LIPVE/210-511    AC A0A340WH02.1
#=GS A0A4W5RW13_9TELE/217-537    AC A0A4W5RW13.1
#=GS Q7PWS3_ANOGA/194-500        AC Q7PWS3.1
#=GS A0A498LI54_LABRO/217-537    AC A0A498LI54.1
#=GS A0A1U8DZ25_ALLSI/131-451    AC A0A1U8DZ25.1
#=GS A0A4W5QBB3_9TELE/199-530    AC A0A4W5QBB3.1
#=GS A0A267GN49_9PLAT/1-291      AC A0A267GN49.1
#=GS A0A2U4BN63_TURTR/226-537    AC A0A2U4BN63.1
#=GS A0A5A9MZ89_9TELE/196-497    AC A0A5A9MZ89.1
#=GS A0A340YEJ1_LIPVE/200-520    AC A0A340YEJ1.1
#=GS A0A6G0V5U8_9BILA/228-539    AC A0A6G0V5U8.1
#=GS A0A0A0AS69_CHAVO/138-441    AC A0A0A0AS69.1
#=GS A0A484H046_SOUCH/218-538    AC A0A484H046.1
#=GS A0A158PD58_ANGCS/122-167    AC A0A158PD58.1
#=GS A0A493U240_ANAPP/210-518    AC A0A493U240.1
#=GS A0A3Q3W2V3_MOLML/196-527    AC A0A3Q3W2V3.1
#=GS A0A026VTV1_OOCBI/227-553    AC A0A026VTV1.1
#=GS G5BJ01_HETGA/35-355         AC G5BJ01.1
#=GS B0WLH9_CULQU/1-145          AC B0WLH9.1
#=GS A0A5F9CMP9_RABIT/189-510    AC A0A5F9CMP9.1
#=GS A0A4W5QDV8_9TELE/213-535    AC A0A4W5QDV8.1
#=GS A0A3Q0HHK1_ALLSI/123-424    AC A0A3Q0HHK1.1
#=GS A0A2I4BY79_9TELE/243-564    AC A0A2I4BY79.1
#=GS E2B9T9_HARSA/283-607        AC E2B9T9.1
#=GS A0A663DUK9_AQUCH/253-576    AC A0A663DUK9.1
#=GS A0A670J494_PODMU/280-632    AC A0A670J494.1
#=GS A0A4W6FVT1_LATCA/219-540    AC A0A4W6FVT1.1
#=GS W5LU60_ASTMX/232-552        AC W5LU60.2
#=GS A0A672TES6_STRHB/213-534    AC A0A672TES6.1
#=GS A0A671ELE2_RHIFE/177-499    AC A0A671ELE2.1
#=GS A0A401PXQ3_SCYTO/229-544    AC A0A401PXQ3.1
#=GS A0A091FYE2_9AVES/1-319      AC A0A091FYE2.1
#=GS A0A4Z2D3M9_SCHJA/402-505    AC A0A4Z2D3M9.1
#=GS A0A3Q1CWG3_AMPOC/207-522    AC A0A3Q1CWG3.1
#=GS A0A3Q1BZH9_AMPOC/196-527    AC A0A3Q1BZH9.1
#=GS A0A6I8TEK4_AEDAE/263-552    AC A0A6I8TEK4.1
#=GS A0A1V9ZBC4_9STRA/3-246      AC A0A1V9ZBC4.1
#=GS A0A183P4C1_9TREM/163-317    AC A0A183P4C1.1
#=GS A0A1S3FPK7_DIPOR/50-370     AC A0A1S3FPK7.1
#=GS A0A099YZY5_TINGU/132-450    AC A0A099YZY5.1
#=GS A0A3P8HNB4_TRIRE/142-252    AC A0A3P8HNB4.1
#=GS A0A5J5CW08_9PERO/141-428    AC A0A5J5CW08.1
#=GS A0A672JQZ8_SALFA/231-541    AC A0A672JQZ8.1
#=GS A0A016T7M7_9BILA/185-390    AC A0A016T7M7.1
#=GS H2SHS3_TAKRU/177-498        AC H2SHS3.3
#=GS A0A060WLD8_ONCMY/222-541    AC A0A060WLD8.1
#=GS A0A5N4DL85_CAMDR/210-511    AC A0A5N4DL85.1
#=GS A0A369S4J8_9METZ/206-579    AC A0A369S4J8.1
#=GS A0A091QUX8_MERNU/158-320    AC A0A091QUX8.1
#=GS G0PC90_CAEBE/57-279         AC G0PC90.1
#=GS G5BG73_HETGA/1-310          AC G5BG73.1
#=GS A0A4U5UUY0_COLLU/220-540    AC A0A4U5UUY0.1
#=GS H2YUA5_CIOSA/269-582        AC H2YUA5.1
#=GS A0A455CBV7_PHYMC/210-511    AC A0A455CBV7.1
#=GS A0A0V1GZB7_9BILA/201-523    AC A0A0V1GZB7.1
#=GS A0A267GF82_9PLAT/248-550    AC A0A267GF82.1
#=GS A0A3M7RVM5_BRAPC/275-610    AC A0A3M7RVM5.1
#=GS A0A1V4KD55_PATFA/1-100      AC A0A1V4KD55.1
#=GS A0A0L0SXM6_ALLM3/49-261     AC A0A0L0SXM6.1
#=GS H0Y136_OTOGA/226-537        AC H0Y136.1
#=GS A0A068S713_9FUNG/151-485    AC A0A068S713.1
#=GS A0A6A4W0L2_AMPAM/204-531    AC A0A6A4W0L2.1
#=GS A0A402FTS9_9SAUR/229-537    AC A0A402FTS9.1
#=GS A0A0L8IGT0_OCTBM/234-554    AC A0A0L8IGT0.1
#=GS A0A4W5RZX2_9TELE/227-548    AC A0A4W5RZX2.1
#=GS A0A2K6A0A6_MANLE/206-507    AC A0A2K6A0A6.1
#=GS G1MD51_AILME/189-510        AC G1MD51.1
#=GS A0A673BVN2_9TELE/203-379    AC A0A673BVN2.1
#=GS A0A2K6PSF4_RHIRO/189-467    AC A0A2K6PSF4.1
#=GS A8WZ70_CAEBR/200-407        AC A8WZ70.2
#=GS A0A3R7H6M7_CLOSI/366-460    AC A0A3R7H6M7.1
#=GS A0A340XVY7_LIPVE/2-205      AC A0A340XVY7.1
#=GS A0A226PZ20_COLVI/172-495    AC A0A226PZ20.1
#=GS H0VQV3_CAVPO/211-512        AC H0VQV3.1
#=GS A0A2K6WCW9_ONCVO/211-519    AC A0A2K6WCW9.1
#=GS A0A3Q3S1M5_9TELE/196-527    AC A0A3Q3S1M5.1
#=GS A0A1L8HQJ0_XENLA/217-537    AC A0A1L8HQJ0.1
#=GS A0A401SDI3_CHIPU/236-556    AC A0A401SDI3.1
#=GS FZD3_CHICK/1-76             AC Q9PTW3.1
#=GS L8HZV1_9CETA/165-496        AC L8HZV1.1
#=GS T1H9Y8_RHOPR/234-402        AC T1H9Y8.1
#=GS A0A672GW82_SALFA/197-528    AC A0A672GW82.1
#=GS G3NMF6_GASAC/185-508        AC G3NMF6.1
#=GS A0A091VHJ1_PHORB/130-450    AC A0A091VHJ1.1
#=GS A0A2Y9SHP0_PHYMC/218-538    AC A0A2Y9SHP0.1
#=GS A0A1S3EUS1_DIPOR/244-564    AC A0A1S3EUS1.1
#=GS A0A0J7LBZ0_LASNI/241-576    AC A0A0J7LBZ0.1
#=GS A0A498MFT8_LABRO/213-562    AC A0A498MFT8.1
#=GS A0A060WNL5_ONCMY/156-287    AC A0A060WNL5.1
#=GS A0A195E4N0_9HYME/393-694    AC A0A195E4N0.1
#=GS A0A3Q3GF20_9LABR/205-526    AC A0A3Q3GF20.1
#=GS A0A1D2MGQ9_ORCCI/244-578    AC A0A1D2MGQ9.1
#=GS A0A2K5C2S9_AOTNA/219-539    AC A0A2K5C2S9.1
#=GS W5L7T2_ASTMX/166-484        AC W5L7T2.2
#=GS A0A060W3V6_ONCMY/200-521    AC A0A060W3V6.1
#=GS A0A1D1UVD4_RAMVA/254-588    AC A0A1D1UVD4.1
#=GS A0A183JXX3_9TREM/312-440    AC A0A183JXX3.1
#=GS A0A1U8DC17_ALLSI/6-148      AC A0A1U8DC17.1
#=GS A0A090MVS3_STRRB/226-535    AC A0A090MVS3.1
#=GS A0A3Q7R9J6_VULVU/348-668    AC A0A3Q7R9J6.1
#=GS A0A0N4YI60_NIPBR/31-308     AC A0A0N4YI60.1
#=GS A0A455B9D4_PHYMC/133-464    AC A0A455B9D4.1
#=GS A0A0R3WF01_TAEAS/284-621    AC A0A0R3WF01.1
#=GS A0A195FKC0_9HYME/218-551    AC A0A195FKC0.1
#=GS A0A665WQV0_ECHNA/242-573    AC A0A665WQV0.1
#=GS A0A2P4SH90_BAMTH/64-407     AC A0A2P4SH90.1
#=GS A0A267G042_9PLAT/245-574    AC A0A267G042.1
#=GS A0A0V1PH72_9BILA/211-535    AC A0A0V1PH72.1
#=GS G3V954_RAT/240-560          AC G3V954.1
#=GS A0A2K6RBZ4_RHIRO/193-514    AC A0A2K6RBZ4.1
#=GS A0A3Q3N8C6_9LABR/188-470    AC A0A3Q3N8C6.1
#=GS A0A452RPB0_URSAM/192-514    AC A0A452RPB0.1
#=GS D2HB98_AILME/195-515        AC D2HB98.1
#=GS A0A091I2S5_CALAN/92-395     AC A0A091I2S5.1
#=GS A0A4W3HYU3_CALMI/218-535    AC A0A4W3HYU3.1
#=GS A0A674HG99_TAEGU/159-460    AC A0A674HG99.1
#=GS A0A4W5MZX9_9TELE/198-519    AC A0A4W5MZX9.1
#=GS A0A091EHX8_CORBR/1-319      AC A0A091EHX8.1
#=GS A0A5J4NJV5_9TREM/473-591    AC A0A5J4NJV5.1
#=GS A0A3P8Z683_ESOLU/200-531    AC A0A3P8Z683.1
#=GS A0A1V9X2V6_9ACAR/220-532    AC A0A1V9X2V6.1
#=GS A0A672FLG4_SALFA/218-533    AC A0A672FLG4.1
#=GS A0A2Y9ETN6_PHYMC/66-387     AC A0A2Y9ETN6.1
#=GS H2YUA7_CIOSA/196-509        AC H2YUA7.1
#=GS G1SAN5_NOMLE/218-538        AC G1SAN5.1
#=GS A0A498LCT3_LABRO/213-531    AC A0A498LCT3.1
#=GS W5QC50_SHEEP/110-421        AC W5QC50.1
#=GS A0A195CJQ9_9HYME/292-593    AC A0A195CJQ9.1
#=GS A0A3Q1GUP7_9TELE/230-551    AC A0A3Q1GUP7.1
#=GS A0A091L9N0_CATAU/117-418    AC A0A091L9N0.1
#=GS F7AS02_HORSE/206-500        AC F7AS02.2
#=GS A0A5N3UJW5_MUNRE/41-99      AC A0A5N3UJW5.1
#=GS A0A498L3F5_LABRO/222-528    AC A0A498L3F5.1
#=GS A0A0L7R8D6_9HYME/226-551    AC A0A0L7R8D6.1
#=GS H3ATE6_LATCH/132-453        AC H3ATE6.1
#=GS A0A2U9CRJ3_SCOMX/217-537    AC A0A2U9CRJ3.1
#=GS H2LH10_ORYLA/217-537        AC H2LH10.2
#=GS A0A5N4AFU8_PHOPY/246-560    AC A0A5N4AFU8.1
#=GS A0A1U8BMJ3_MESAU/240-560    AC A0A1U8BMJ3.1
#=GS A0A182H402_AEDAL/4-77       AC A0A182H402.1
#=GS A0A2K5KQZ5_CERAT/159-460    AC A0A2K5KQZ5.1
#=GS A0A673Y6X4_SALTR/205-506    AC A0A673Y6X4.1
#=GS A0A493TW05_ANAPP/261-616    AC A0A493TW05.1
#=GS B4L0E7_DROMO/243-574        AC B4L0E7.2
#=GS A0A060ZHB9_ONCMY/11-261     AC A0A060ZHB9.1
#=GS V8P4U1_OPHHA/105-363        AC V8P4U1.1
#=GS A0A397TYL1_9GLOM/222-542    AC A0A397TYL1.1
#=GS A0A4S2LV38_OPIFE/572-694    AC A0A4S2LV38.1
#=GS A0A183VRY1_TRIRE/161-443    AC A0A183VRY1.1
#=GS A0A1I3MUS7_9FLAO/31-186     AC A0A1I3MUS7.1
#=GS A0A4W5KKP6_9TELE/234-544    AC A0A4W5KKP6.1
#=GS A0A2G8KYK1_STIJA/1-96       AC A0A2G8KYK1.1
#=GS H3CS14_TETNG/186-506        AC H3CS14.1
#=GS F7C0H4_HORSE/189-510        AC F7C0H4.2
#=GS A0A5A9NY18_9TELE/216-536    AC A0A5A9NY18.1
#=GS A0A0F8B907_LARCR/220-540    AC A0A0F8B907.1
#=GS T1JZ26_TETUR/239-549        AC T1JZ26.1
#=GS A0A091FQA3_CORBR/1-208      AC A0A091FQA3.1
#=GS K7J481_NASVI/253-573        AC K7J481.1
#=GS Q8QFM3_DANRE/228-548        AC Q8QFM3.1
#=GS A0A368GUB0_ANCCA/207-473    AC A0A368GUB0.1
#=GS A0A226PEV9_COLVI/126-447    AC A0A226PEV9.1
#=GS B4H824_DROPE/240-329        AC B4H824.1
#=GS W5Q564_SHEEP/198-519        AC W5Q564.1
#=GS A0A3P8WQZ6_CYNSE/216-536    AC A0A3P8WQZ6.1
#=GS A0A668A7K6_9TELE/222-542    AC A0A668A7K6.1
#=GS A0A674EXP3_SALTR/202-523    AC A0A674EXP3.1
#=GS A0A091VLP2_OPIHO/1-129      AC A0A091VLP2.1
#=GS H3ERM3_PRIPA/286-515        AC H3ERM3.2
#=GS A0A183MR20_9TREM/642-765    AC A0A183MR20.1
#=GS G5EF44_CAEEL/206-442        AC G5EF44.1
#=GS H3BEE0_LATCH/222-542        AC H3BEE0.1
#=GS A0A091HWJ7_BUCRH/201-521    AC A0A091HWJ7.1
#=GS A0A3N0Z9R6_ANAGA/221-533    AC A0A3N0Z9R6.1
#=GS A0A0V1CX13_TRIBR/185-512    AC A0A0V1CX13.1
#=GS A0A4S2LBG0_OPIFE/563-664    AC A0A4S2LBG0.1
#=GS B7PAJ1_IXOSC/186-494        AC B7PAJ1.1
#=GS A0A672HN22_SALFA/215-535    AC A0A672HN22.1
#=GS A0A3Q1G241_9TELE/224-544    AC A0A3Q1G241.1
#=GS A0A672G0U6_SALFA/227-548    AC A0A672G0U6.1
#=GS M4B0Z5_XIPMA/230-540        AC M4B0Z5.2
#=GS A8WWU4_CAEBR/220-553        AC A8WWU4.1
#=GS A0A3P8ZCU7_ESOLU/241-552    AC A0A3P8ZCU7.2
#=GS S7N971_MYOBR/106-407        AC S7N971.1
#=GS A0A2K6FXU7_PROCO/217-537    AC A0A2K6FXU7.1
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#=GS U3KL27_FICAL/233-553        AC U3KL27.1
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#=GS A0A183JHR6_9TREM/1-60       AC A0A183JHR6.1
#=GS A0A4X2K7E8_VOMUR/231-542    AC A0A4X2K7E8.1
#=GS G0MFK4_CAEBE/221-554        AC G0MFK4.1
#=GS A0A671FM57_RHIFE/311-638    AC A0A671FM57.1
#=GS A0A183W3H5_TRIRE/357-617    AC A0A183W3H5.1
#=GS A0A498NEW6_LABRO/225-537    AC A0A498NEW6.1
#=GS A0A2P4SIF7_BAMTH/1-46       AC A0A2P4SIF7.1
#=GS A0A0V0TCZ9_9BILA/277-608    AC A0A0V0TCZ9.1
#=GS A0A4S2LBG0_OPIFE/734-849    AC A0A4S2LBG0.1
#=GS A0A3Q2ZA18_KRYMA/197-507    AC A0A3Q2ZA18.1
#=GS A0A3Q2CMZ5_CYPVA/228-549    AC A0A3Q2CMZ5.1
#=GS A0A5N5P4N0_PANHP/219-539    AC A0A5N5P4N0.1
#=GS A0A340WWU9_LIPVE/308-634    AC A0A340WWU9.1
#=GS A0A674MJZ3_TAKRU/212-519    AC A0A674MJZ3.1
#=GS A0A0R3T0W0_RODNA/287-623    AC A0A0R3T0W0.2
#=GS U3IFV9_ANAPP/223-546        AC U3IFV9.2
#=GS A0A3P6SR86_LITSI/205-537    AC A0A3P6SR86.1
#=GS A0A1S3IJC8_LINUN/227-556    AC A0A1S3IJC8.1
#=GS A0A484DA71_PERFV/224-543    AC A0A484DA71.1
#=GS A0A5N5Q009_PANHP/222-542    AC A0A5N5Q009.1
#=GS A0A2U3X3T3_ODORO/265-617    AC A0A2U3X3T3.1
#=GS A0A5K4F4J1_SCHMA/566-689    AC A0A5K4F4J1.1
#=GS A0A485NKT3_LYNPA/222-553    AC A0A485NKT3.1
#=GS A0A3Q7WP77_URSAR/193-514    AC A0A3Q7WP77.1
#=GS A0A0B1SCU8_OESDE/46-235     AC A0A0B1SCU8.1
#=GS A0A158NWQ8_ATTCE/86-211     AC A0A158NWQ8.1
#=GS A0A553RCC0_9TELE/195-516    AC A0A553RCC0.1
#=GS A0A3Q1FM04_9TELE/220-539    AC A0A3Q1FM04.1
#=GS A0A0V1H0B2_9BILA/229-551    AC A0A0V1H0B2.1
#=GS M3XPH4_MUSPF/193-514        AC M3XPH4.1
#=GS A0A484DIK8_PERFV/224-525    AC A0A484DIK8.1
#=GS A0A091VQQ0_NIPNI/200-520    AC A0A091VQQ0.1
#=GS A0A5C6NBZ8_9TELE/196-527    AC A0A5C6NBZ8.1
#=GS A0A067QHH7_ZOONE/204-540    AC A0A067QHH7.1
#=GS A0A0N4W4L0_HAEPC/124-289    AC A0A0N4W4L0.1
#=GS A0A6H5H4G2_9HEMI/244-570    AC A0A6H5H4G2.1
#=GS A0A267DQ53_9PLAT/251-565    AC A0A267DQ53.1
#=GS H0YT73_TAEGU/252-575        AC H0YT73.2
#=GS V9DV66_PHYPR/3-133          AC V9DV66.1
#=GS V3ZM42_LOTGI/201-533        AC V3ZM42.1
#=GS SMO_HUMAN/221-552           AC Q99835.1
#=GS SMO_HUMAN/221-552           DR PDB; 4O9R A; 221-551;
#=GS SMO_HUMAN/221-552           DR PDB; 5V56 A; 221-552;
#=GS SMO_HUMAN/221-552           DR PDB; 4N4W A; 221-552;
#=GS SMO_HUMAN/221-552           DR PDB; 4QIM A; 221-552;
#=GS SMO_HUMAN/221-552           DR PDB; 4JKV B; 221-552;
#=GS SMO_HUMAN/221-552           DR PDB; 5V57 A; 221-552;
#=GS SMO_HUMAN/221-552           DR PDB; 5L7D B; 221-551;
#=GS SMO_HUMAN/221-552           DR PDB; 5V56 B; 221-552;
#=GS SMO_HUMAN/221-552           DR PDB; 5L7D A; 221-552;
#=GS SMO_HUMAN/221-552           DR PDB; 4JKV A; 221-550;
#=GS SMO_HUMAN/221-552           DR PDB; 5L7I B; 221-552;
#=GS SMO_HUMAN/221-552           DR PDB; 5L7I A; 221-551;
#=GS SMO_HUMAN/221-552           DR PDB; 5V57 B; 221-552;
#=GS SMO_HUMAN/221-552           DR PDB; 6OT0 R; 221-552;
#=GS SMO_HUMAN/221-552           DR PDB; 4QIN A; 221-551;
#=GS K7F134_PELSI/204-524        AC K7F134.1
#=GS H2ZZD7_LATCH/198-512        AC H2ZZD7.1
#=GS A0A504YEH4_FASGI/129-175    AC A0A504YEH4.1
#=GS E3LJT9_CAERE/221-529        AC E3LJT9.1
#=GS L5KQ09_PTEAL/223-554        AC L5KQ09.1
#=GS A0A087YEV9_POEFO/225-546    AC A0A087YEV9.2
#=GS A0A093ER32_GAVST/105-285    AC A0A093ER32.1
#=GS H2M7Q8_ORYLA/226-545        AC H2M7Q8.2
#=GS A0A226NPP6_COLVI/358-502    AC A0A226NPP6.1
#=GS A0A5N5TGW1_9CRUS/4-176      AC A0A5N5TGW1.1
#=GS K7FD12_PELSI/211-520        AC K7FD12.1
#=GS A0A430Q7A8_SCHBO/312-441    AC A0A430Q7A8.1
#=GS A0A5F7ZNQ5_MACMU/210-511    AC A0A5F7ZNQ5.1
#=GS A0A401PR31_SCYTO/232-540    AC A0A401PR31.1
#=GS A0A0V1CWR3_TRIBR/185-512    AC A0A0V1CWR3.1
#=GS A0A3Q4G1N3_NEOBR/225-537    AC A0A3Q4G1N3.1
#=GS A0A2T7P625_POMCA/240-338    AC A0A2T7P625.1
#=GS A0A226NAI7_CALSU/1-90       AC A0A226NAI7.1
#=GS A0A401RW53_CHIPU/201-502    AC A0A401RW53.1
#=GS A0A553MU89_9TELE/347-655    AC A0A553MU89.1
#=GS A0A3P8XZW8_ESOLU/193-514    AC A0A3P8XZW8.2
#=GS A0A3P8TCI7_AMPPE/196-517    AC A0A3P8TCI7.1
#=GS A0A369SIM8_9METZ/197-518    AC A0A369SIM8.1
#=GS D3BM93_POLPP/236-548        AC D3BM93.1
#=GS G3PRW0_GASAC/219-490        AC G3PRW0.1
#=GS A0A3Q2WBA9_HAPBU/217-537    AC A0A3Q2WBA9.1
#=GS A0A452DUD0_CAPHI/226-537    AC A0A452DUD0.1
#=GS I3KZU0_ORENI/239-559        AC I3KZU0.1
#=GS A0A2G5T829_9PELO/221-529    AC A0A2G5T829.1
#=GS A0A6H5IQC3_9HYME/720-1057   AC A0A6H5IQC3.1
#=GS A0A087YG55_POEFO/217-537    AC A0A087YG55.2
#=GS A0A091TWX5_PHORB/201-521    AC A0A091TWX5.1
#=GS A0A087VI49_BALRE/50-363     AC A0A087VI49.1
#=GS A0A2K6NDG0_RHIRO/137-404    AC A0A2K6NDG0.1
#=GS A0A226PY96_COLVI/222-542    AC A0A226PY96.1
#=GS A0A672HUP0_SALFA/222-455    AC A0A672HUP0.1
#=GS A0A4W4FWP3_ELEEL/200-531    AC A0A4W4FWP3.1
#=GS A0A662Z1A3_ACIRT/234-544    AC A0A662Z1A3.1
#=GS A0A182H9U6_AEDAL/269-581    AC A0A182H9U6.1
#=GS A0A4W5KAU2_9TELE/219-539    AC A0A4W5KAU2.1
#=GS A0A1S4ERK3_DIACI/23-182     AC A0A1S4ERK3.1
#=GS S7PG13_MYOBR/151-224        AC S7PG13.1
#=GS A0A3Q3XC87_MOLML/210-526    AC A0A3Q3XC87.1
#=GS A0A0V1PH97_9BILA/211-482    AC A0A0V1PH97.1
#=GS A0A6I8NGW6_ORNAN/256-575    AC A0A6I8NGW6.1
#=GS A0A653BH85_CALMS/151-209    AC A0A653BH85.1
#=GS A0A452GUM0_9SAUR/182-513    AC A0A452GUM0.1
#=GS A0A452IID8_9SAUR/227-540    AC A0A452IID8.1
#=GS A0A210PQV2_MIZYE/196-530    AC A0A210PQV2.1
#=GS L5JS26_PTEAL/60-180         AC L5JS26.1
#=GS A0A091XC45_OPIHO/179-500    AC A0A091XC45.1
#=GS A0A5N3X8S9_MUNRE/218-538    AC A0A5N3X8S9.1
#=GS A0A3P8YTF4_ESOLU/219-539    AC A0A3P8YTF4.2
#=GS A0A3S3NQN7_9ACAR/481-580    AC A0A3S3NQN7.1
#=GS A0A093BEZ2_CHAPE/28-348     AC A0A093BEZ2.1
#=GS J9JUF4_ACYPI/255-564        AC J9JUF4.1
#=GS A0A1X7VNE1_AMPQE/46-267     AC A0A1X7VNE1.1
#=GS A0A2Z6Q2L8_9GLOM/227-541    AC A0A2Z6Q2L8.1
#=GS A0A2I0UQK0_LIMLA/231-521    AC A0A2I0UQK0.1
#=GS A0A183JHR6_9TREM/152-304    AC A0A183JHR6.1
#=GS A0A183MEQ1_9TREM/316-456    AC A0A183MEQ1.1
#=GS A0A1D1VV00_RAMVA/196-537    AC A0A1D1VV00.1
#=GS A0A452EZH8_CAPHI/189-510    AC A0A452EZH8.1
#=GS H9GGS9_ANOCA/193-514        AC H9GGS9.1
#=GS A0A1D2ME67_ORCCI/224-311    AC A0A1D2ME67.1
#=GS A0A1D5NTJ0_CHICK/193-514    AC A0A1D5NTJ0.1
#=GS A0A093IN45_DRYPU/119-420    AC A0A093IN45.1
#=GS A0A2K5PHT8_CEBCA/223-545    AC A0A2K5PHT8.1
#=GS A0A1S3AMT0_ERIEU/197-498    AC A0A1S3AMT0.1
#=GS W5JW01_ANODA/274-621        AC W5JW01.1
#=GS A0A096N985_PAPAN/226-537    AC A0A096N985.1
#=GS A0A5E4AIN2_MARMO/222-544    AC A0A5E4AIN2.1
#=GS A0A091KIW9_9GRUI/33-352     AC A0A091KIW9.1
#=GS A0A075A636_9TREM/613-716    AC A0A075A636.1
#=GS A0A0L0BY44_LUCCU/248-546    AC A0A0L0BY44.1
#=GS A0A3Q2I4Z2_HORSE/244-564    AC A0A3Q2I4Z2.1
#=GS A0A673U1U0_SURSU/193-514    AC A0A673U1U0.1
#=GS A0A084WFW9_ANOSI/233-562    AC A0A084WFW9.1
#=GS B4MT43_DROWI/197-497        AC B4MT43.2
#=GS A0A0V1CJT4_TRIBR/276-640    AC A0A0V1CJT4.1
#=GS A0A5F8AC06_MACMU/210-511    AC A0A5F8AC06.1
#=GS A0A4W6F9R8_LATCA/205-506    AC A0A4W6F9R8.1
#=GS A0A673VKF9_SALTR/189-510    AC A0A673VKF9.1
#=GS A0A2K6P5M1_RHIRO/220-551    AC A0A2K6P5M1.1
#=GS A0A3Q3FB29_KRYMA/215-516    AC A0A3Q3FB29.1
#=GS A0A674B668_SALTR/207-526    AC A0A674B668.1
#=GS A0A4X2JLI6_VOMUR/218-538    AC A0A4X2JLI6.1
#=GS A0A0R3UC25_9CEST/233-574    AC A0A0R3UC25.1
#=GS A0A4W3HB10_CALMI/475-518    AC A0A4W3HB10.1
#=GS A0A2K5ZUC1_MANLE/218-538    AC A0A2K5ZUC1.1
#=GS A0A671F9Q3_RHIFE/193-514    AC A0A671F9Q3.1
#=GS H3BHZ5_LATCH/219-539        AC H3BHZ5.1
#=GS A0A452RKZ1_URSAM/189-510    AC A0A452RKZ1.1
#=GS A0A3P8HFN7_9TREM/153-302    AC A0A3P8HFN7.1
#=GS A0A452J099_9SAUR/225-544    AC A0A452J099.1
#=GS K7IPU4_NASVI/219-543        AC K7IPU4.1
#=GS A0A6H5IXB0_9HYME/430-570    AC A0A6H5IXB0.1
#=GS A0A3B5QBL9_XIPMA/225-546    AC A0A3B5QBL9.1
#=GS H2YUB0_CIOSA/189-493        AC H2YUB0.1
#=GS A0A3P9P3X7_POERE/225-546    AC A0A3P9P3X7.1
#=GS A0A226PAD0_COLVI/1-29       AC A0A226PAD0.1
#=GS A0A670JD90_PODMU/203-534    AC A0A670JD90.1
#=GS A0A2A2LE18_9BILA/213-420    AC A0A2A2LE18.1
#=GS Q7Q2X0_ANOGA/5-169          AC Q7Q2X0.3
#=GS A0A672UH10_STRHB/186-517    AC A0A672UH10.1
#=GS A0A4W6FA92_LATCA/196-527    AC A0A4W6FA92.1
#=GS A0A498SBW2_ACAVI/190-259    AC A0A498SBW2.1
#=GS A0A0P7YL39_SCLFO/623-699    AC A0A0P7YL39.1
#=GS B4J3D8_DROGR/317-629        AC B4J3D8.1
#=GS A0A195ERS4_9HYME/414-738    AC A0A195ERS4.1
#=GS A0A158QQW8_HAEPC/208-525    AC A0A158QQW8.1
#=GS A0A401SSK8_CHIPU/239-552    AC A0A401SSK8.1
#=GS G3VPF7_SARHA/195-516        AC G3VPF7.1
#=GS H0X9M1_OTOGA/220-551        AC H0X9M1.1
#=GS E2RIM4_CANLF/204-523        AC E2RIM4.3
#=GS A0A074ZZP7_9TREM/752-939    AC A0A074ZZP7.1
#=GS A0A2Y9TAB6_PHYMC/193-514    AC A0A2Y9TAB6.1
#=GS A0A444UC36_ACIRT/192-514    AC A0A444UC36.1
#=GS A0A1V4K4U3_PATFA/226-546    AC A0A1V4K4U3.1
#=GS A0A091JZT2_COLST/117-418    AC A0A091JZT2.1
#=GS A0A0R3SRD9_HYMDI/193-555    AC A0A0R3SRD9.1
#=GS W4G8X1_9STRA/93-271         AC W4G8X1.1
#=GS A0A5A9P1V4_9TELE/223-543    AC A0A5A9P1V4.1
#=GS A0A0B2V5T7_TOXCA/175-483    AC A0A0B2V5T7.1
#=GS A0A674EPX9_SALTR/216-547    AC A0A674EPX9.1
#=GS A0A2I2YWP4_GORGO/218-538    AC A0A2I2YWP4.1
#=GS F6VFD0_MONDO/213-514        AC F6VFD0.3
#=GS A0A4W2GU92_BOBOX/269-614    AC A0A4W2GU92.1
#=GS Q16U84_AEDAE/198-366        AC Q16U84.2
#=GS A0A452SK38_URSAM/244-564    AC A0A452SK38.1
#=GS A0A444TL31_ARMVU/287-456    AC A0A444TL31.1
#=GS A0A5N5M7B0_PANHP/459-505    AC A0A5N5M7B0.1
#=GS U4UBT8_DENPD/1-267          AC U4UBT8.1
#=GS A0A2Y9T457_PHYMC/189-510    AC A0A2Y9T457.1
#=GS W6UX10_ECHGR/193-549        AC W6UX10.1
#=GS A0A096N7F2_PAPAN/244-564    AC A0A096N7F2.1
#=GS A0A665XG08_ECHNA/222-532    AC A0A665XG08.1
#=GS A0A091INS2_EGRGA/55-372     AC A0A091INS2.1
#=GS A0A5K4F4J1_SCHMA/783-934    AC A0A5K4F4J1.1
#=GS A0A3B3ICF1_ORYLA/231-586    AC A0A3B3ICF1.1
#=GS A0A0Q3M207_AMAAE/159-460    AC A0A0Q3M207.1
#=GS A0A3P9B3H1_9CICH/196-517    AC A0A3P9B3H1.1
#=GS A0A0R3X078_HYDTA/311-437    AC A0A0R3X078.1
#=GS W5K860_ASTMX/198-499        AC W5K860.2
#=GS A0A674BN74_SALTR/229-539    AC A0A674BN74.1
#=GS A0A5N4E028_CAMDR/151-482    AC A0A5N4E028.1
#=GS A0A5S6PS99_BRUMA/212-443    AC A0A5S6PS99.1
#=GS A0A3P7IFC0_STRVU/1-74       AC A0A3P7IFC0.1
#=GS A0A1V9WZU9_9ACAR/222-533    AC A0A1V9WZU9.1
#=GS B4M2Y5_DROVI/253-555        AC B4M2Y5.1
#=GS A0A4V5P898_MONMO/239-570    AC A0A4V5P898.1
#=GS H2Y2T1_CIOIN/217-339        AC H2Y2T1.1
#=GS A0A3S1A272_ELYCH/334-634    AC A0A3S1A272.1
#=GS M3ZGK7_XIPMA/219-532        AC M3ZGK7.2
#=GS A0A5N4BZP5_CAMDR/138-240    AC A0A5N4BZP5.1
#=GS FZD7_CHICK/238-557          AC O57329.1
#=GS FZD9_CHICK/28-348           AC Q9IA02.1
#=GS A0A668ABQ6_9TELE/188-508    AC A0A668ABQ6.1
#=GS A0A504YEH4_FASGI/202-332    AC A0A504YEH4.1
#=GS A0A2H2IMH4_CAEJA/221-554    AC A0A2H2IMH4.1
#=GS A0A0P7U393_SCLFO/327-492    AC A0A0P7U393.1
#=GS G3QL33_GORGO/220-551        AC G3QL33.2
#=GS A0A158PNB6_ANISI/157-420    AC A0A158PNB6.1
#=GS A0A1I7VIT3_LOALO/206-315    AC A0A1I7VIT3.1
#=GS FZD9_MOUSE/223-545          AC Q9R216.1
#=GS A0A182ET24_ONCOC/1-91       AC A0A182ET24.1
#=GS A0A484CUR6_PERFV/230-546    AC A0A484CUR6.1
#=GS A0A0Q3UQG6_AMAAE/229-550    AC A0A0Q3UQG6.1
#=GS A0A2G8JWU9_STIJA/211-541    AC A0A2G8JWU9.1
#=GS A0A4V3SEJ6_OPIFE/192-560    AC A0A4V3SEJ6.1
#=GS A0A1V4KBG2_PATFA/175-498    AC A0A1V4KBG2.1
#=GS A0A077Z8U6_TRITR/310-631    AC A0A077Z8U6.1
#=GS A0A2K5BYZ5_AOTNA/226-537    AC A0A2K5BYZ5.1
#=GS G3T897_LOXAF/193-514        AC G3T897.1
#=GS A0A2R9ACM7_PANPA/241-561    AC A0A2R9ACM7.1
#=GS A0A4C1ZMM3_EUMVA/294-463    AC A0A4C1ZMM3.1
#=GS A0A672GH71_SALFA/197-518    AC A0A672GH71.1
#=GS L8GTI2_ACACA/180-500        AC L8GTI2.1
#=GS A0A0L7LT04_9NEOP/190-301    AC A0A0L7LT04.1
#=GS A0A4U5UUV4_COLLU/124-426    AC A0A4U5UUV4.1
#=GS A0A452DWU7_CAPHI/218-538    AC A0A452DWU7.1
#=GS A0A3P9PG35_POERE/243-563    AC A0A3P9PG35.1
#=GS A0A093I1Q8_FULGA/117-418    AC A0A093I1Q8.1
#=GS A0A0R3X5G6_HYDTA/261-367    AC A0A0R3X5G6.2
#=GS L5M598_MYODS/158-342        AC L5M598.1
#=GS A0A0R3W8E4_TAEAS/517-602    AC A0A0R3W8E4.2
#=GS A0A3Q0D3R8_MESAU/393-529    AC A0A3Q0D3R8.1
#=GS A0A3P7JCQ2_STRVU/1-115      AC A0A3P7JCQ2.1
#=GS A0A553MSB9_9TELE/220-481    AC A0A553MSB9.1
#=GS I3LRD8_PIG/222-544          AC I3LRD8.2
#=GS A0A4U1EUT1_MONMO/244-564    AC A0A4U1EUT1.1
#=GS A0A5J4NU30_9TREM/203-278    AC A0A5J4NU30.1
#=GS A0A2K5M6D0_CERAT/220-540    AC A0A2K5M6D0.1
#=GS A0A226MR34_CALSU/175-455    AC A0A226MR34.1
#=GS A0A0V0ZZM5_9BILA/325-545    AC A0A0V0ZZM5.1
#=GS A0A0V1HGF5_9BILA/604-679    AC A0A0V1HGF5.1
#=GS A0A0V1PH61_9BILA/211-535    AC A0A0V1PH61.1
#=GS A0A060Z8Z4_ONCMY/1-191      AC A0A060Z8Z4.1
#=GS A0A6I8R8M4_XENTR/194-399    AC A0A6I8R8M4.1
#=GS A0A3N0Z5E1_ANAGA/187-507    AC A0A3N0Z5E1.1
#=GS FZD4_CHICK/198-499          AC Q9IA05.1
#=GS A0A2P4SDW4_BAMTH/175-495    AC A0A2P4SDW4.1
#=GS E2QVP7_CANLF/226-537        AC E2QVP7.1
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