#=GF ID   GIY_YIG_3
#=GF AC   PF26468.1
#=GF DE   GIY-YIG domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   UniProtKB:A0A384LQI3
#=GF GA   27.00 27.00;
#=GF TC   27.50 27.40;
#=GF NC   24.50 23.70;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 90746521 -E 1000 --cpu 8 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0418
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents a domain from a family of uncharacterised
#=GF CC   proteins found predominantly in halophilic archaea, specifically
#=GF CC   within the Halobacteria class. The proteins containing this
#=GF CC   domain are typically around 230 to 240 amino acids in length.
#=GF CC   The domain is highly conserved across various species within the
#=GF CC   Stenosarchaea group, indicating a potentially important but yet
#=GF CC   unidentified function. The domain belongs to the GIY-YIG
#=GF CC   superfamily and is thus likely to act as a nuclease. In some
#=GF CC   members of the family this domain is found associated with an
#=GF CC   N-terminal copy of Pfam:PF21818.
#=GF SQ   104
#=GS A0A6A9T6U9_9EURY/1-242    AC A0A6A9T6U9.1
#=GS A0A0D6JEY1_9HYPH/177-402  AC A0A0D6JEY1.1
#=GS A0A0H1REI1_9HYPH/1-233    AC A0A0H1REI1.1
#=GS A0A6B0TDV0_9EURY/1-236    AC A0A6B0TDV0.1
#=GS A0A1T5M0V5_9FIRM/8-111    AC A0A1T5M0V5.1
#=GS A0A1I6HC64_9EURY/1-242    AC A0A1I6HC64.1
#=GS A0A292YRE3_9BACL/2-109    AC A0A292YRE3.1
#=GS A0A089JW76_9BACL/5-213    AC A0A089JW76.1
#=GS A0A316GJZ8_9RHOB/1-233    AC A0A316GJZ8.1
#=GS A0A1N6ZD04_9EURY/1-236    AC A0A1N6ZD04.1
#=GS A0A1H3Y225_9EURY/1-241    AC A0A1H3Y225.1
#=GS A0A7X8NAY3_9FLAO/3-209    AC A0A7X8NAY3.1
#=GS A0A1W6LPZ8_9BACT/13-217   AC A0A1W6LPZ8.1
#=GS U5NDT0_9BURK/5-234        AC U5NDT0.1
#=GS A0A6G2FUB3_9EURY/1-242    AC A0A6G2FUB3.1
#=GS M0CEQ6_9EURY/1-128        AC M0CEQ6.1
#=GS A0A1W2DTW5_9RHOB/8-240    AC A0A1W2DTW5.1
#=GS V4Y9T0_9ARCH/1-235        AC V4Y9T0.1
#=GS A0A1T4XUI6_9CLOT/154-345  AC A0A1T4XUI6.1
#=GS A0A1N6E3X2_9RHOB/2-234    AC A0A1N6E3X2.1
#=GS A0A098M902_9BACL/22-218   AC A0A098M902.1
#=GS C7NQW7_HALUD/1-236        AC C7NQW7.1
#=GS A0A7D5DXD7_9EURY/1-242    AC A0A7D5DXD7.1
#=GS A0A0G3V3A6_9ACTN/4-240    AC A0A0G3V3A6.1
#=GS A0A2C8FCS1_9BACT/138-369  AC A0A2C8FCS1.1
#=GS A0A1M4NEE5_9CLOT/152-348  AC A0A1M4NEE5.1
#=GS A0A327XJT2_9RHOB/2-234    AC A0A327XJT2.1
#=GS A0A343TLU9_9EURY/1-137    AC A0A343TLU9.1
#=GS A0A7W3MYG8_9ACTN/6-233    AC A0A7W3MYG8.1
#=GS A0A5B8FXY0_9RHOB/4-206    AC A0A5B8FXY0.1
#=GS A0A6B0SYR0_9EURY/1-242    AC A0A6B0SYR0.1
#=GS A0A8T4H3B8_9EURY/1-241    AC A0A8T4H3B8.1
#=GS A0A086YSC7_9FIRM/3-212    AC A0A086YSC7.1
#=GS A0A343TLU8_9EURY/1-75     AC A0A343TLU8.1
#=GS A0A0F7KSA1_9SPHN/7-231    AC A0A0F7KSA1.1
#=GS A0A1I7LTD0_9BURK/164-392  AC A0A1I7LTD0.1
#=GS A0A087S115_9ARCH/11-165   AC A0A087S115.1
#=GS A0A2I8VMF9_9EURY/1-242    AC A0A2I8VMF9.1
#=GS A0A4U7F544_9EURY/1-242    AC A0A4U7F544.1
#=GS A0A0Q5IU45_9DEIO/1-221    AC A0A0Q5IU45.1
#=GS K4LF01_THEPS/39-227       AC K4LF01.1
#=GS V4XCU0_9ARCH/1-192        AC V4XCU0.1
#=GS A0A1H3GLJ0_9EURY/1-236    AC A0A1H3GLJ0.1
#=GS A0A1M4ZHL2_9CLOT/141-353  AC A0A1M4ZHL2.1
#=GS A0A4R6KM88_9ACTN/3-229    AC A0A4R6KM88.1
#=GS A0A1I5VCJ6_9FIRM/155-352  AC A0A1I5VCJ6.1
#=GS V4GQU4_9EURY/1-236        AC V4GQU4.1
#=GS A0A838ZU95_9FLAO/1-213    AC A0A838ZU95.1
#=GS A0A7D5GLP3_9EURY/1-236    AC A0A7D5GLP3.1
#=GS A0A133UGG7_9EURY/4-233    AC A0A133UGG7.1
#=GS A0A1I2SQW1_9EURY/4-245    AC A0A1I2SQW1.1
#=GS L0F3V7_DESDL/147-263      AC L0F3V7.1
#=GS A0AA43XJN0_9CLOT/57-264   AC A0AA43XJN0.1
#=GS A0A830GJF7_9EURY/1-47     AC A0A830GJF7.1
#=GS A0A8J7SBN7_9RHOB/2-233    AC A0A8J7SBN7.1
#=GS A6P101_9FIRM/161-348      AC A6P101.1
#=GS D4GVX1_HALVD/1-236        AC D4GVX1.1
#=GS A0A830GIQ2_9EURY/1-94     AC A0A830GIQ2.1
#=GS A0A8J7YHT3_9EURY/1-233    AC A0A8J7YHT3.1
#=GS A0A9E8M1Z7_9BACI/150-346  AC A0A9E8M1Z7.1
#=GS A0A1H6C137_9EURY/1-236    AC A0A1H6C137.1
#=GS L0IAF7_HALRX/1-236        AC L0IAF7.1
#=GS A0A5E4X442_9BURK/1-242    AC A0A5E4X442.1
#=GS A0A7I9VKT1_9BACT/1-240    AC A0A7I9VKT1.1
#=GS C6A4B9_THESM/8-232        AC C6A4B9.1
#=GS S0G1J8_9BACT/3-211        AC S0G1J8.1
#=GS A0A126V695_9RHOB/1-218    AC A0A126V695.1
#=GS A0A1G9J3N1_9RHOB/1-87     AC A0A1G9J3N1.1
#=GS A0A4R4RXE1_9ACTN/3-230    AC A0A4R4RXE1.1
#=GS A0A4Q8R341_9BRAD/3-234    AC A0A4Q8R341.1
#=GS A0A6N7ILL2_9FIRM/1-227    AC A0A6N7ILL2.1
#=GS A0A830GN08_9EURY/1-236    AC A0A830GN08.1
#=GS A0A1T5KYC7_9FIRM/3-210    AC A0A1T5KYC7.1
#=GS A0A133VNH2_9EURY/1-233    AC A0A133VNH2.1
#=GS A0A1B6Z4S8_9SPHN/1-218    AC A0A1B6Z4S8.1
#=GS A0A135L110_9BACI/54-251   AC A0A135L110.1
#=GS B8EPP5_METSB/3-234        AC B8EPP5.1
#=GS S7TJK2_9BACT/172-401      AC S7TJK2.1
#=GS A0A542LV36_9BURK/353-586  AC A0A542LV36.1
#=GS A0A5N8YPT7_9CHLR/2-208    AC A0A5N8YPT7.1
#=GS A0A0F7JUI3_9DEIO/1-185    AC A0A0F7JUI3.1
#=GS A0A418X016_9BURK/2-236    AC A0A418X016.1
#=GS A0A1D9MAS9_9RHOB/2-232    AC A0A1D9MAS9.1
#=GS A0A7X0G2Y0_9ACTN/6-232    AC A0A7X0G2Y0.1
#=GS A0A8J2VND7_9RHOB/1-238    AC A0A8J2VND7.1
#=GS Q2IEP0_ANADE/1-111        AC Q2IEP0.1
#=GS A0A1W1UWI7_9DEIO/4-233    AC A0A1W1UWI7.1
#=GS A0A1D2YT16_9BACI/12-209   AC A0A1D2YT16.1
#=GS A0A1W1VNR9_9BACT/6-208    AC A0A1W1VNR9.1
#=GS A0A927MN27_9ACTN/1-85     AC A0A927MN27.1
#=GS A0A3N6LZU7_9EURY/1-236    AC A0A3N6LZU7.1
#=GS A0A5C8JZV3_9ACTN/1-210    AC A0A5C8JZV3.1
#=GS A0A6B0VTL1_9EURY/1-236    AC A0A6B0VTL1.1
#=GS A0A0X8G8D7_9FLAO/5-212    AC A0A0X8G8D7.1
#=GS A0A370HB89_9HYPH/1-199    AC A0A370HB89.1
#=GS A0A239EMX4_9ACTN/3-230    AC A0A239EMX4.1
#=GS A0A2C9CZX8_9HYPH/1-207    AC A0A2C9CZX8.1
#=GS Q2IUD9_RHOP2/141-375      AC Q2IUD9.1
#=GS A0A1J1AEC5_9EURY/4-245    AC A0A1J1AEC5.1
#=GS A0A844W1H0_9RHOB/1-216    AC A0A844W1H0.1
#=GS E3PVE8_ACESD/137-355      AC E3PVE8.1
#=GS A0A1T4X4Z0_9BACT/4-233    AC A0A1T4X4Z0.1
#=GS A0A840W305_9ACTN/3-232    AC A0A840W305.1
#=GS A0A849L6Y2_9RHOB/3-232    AC A0A849L6Y2.1
A0A6A9T6U9_9EURY/1-242               .............................................MARRADVDRLYDLLDALERRVGGARKLKDCTGYMDWP.DRGVYFFLEPGETRA......TTDQRRVTRVGTHAVSQGSSTTLWDRLKQHYGTGSas...adhPHGGNHRGSVYRKRVGEAIIEKYALH.eDYP.EWD....ARWSgierDRSAV..........REAEYVLERRVSAYIRE.Q.PFL.WVTLDDEPSADSDRAVLERSVIALLSNAGR..ESVDPRDDDWLGRY...SRSRAIRESGLWNVAHV...E.D..DYDPAALDLLESALEDTT--pp........................
A0A0D6JEY1_9HYPH/177-402             ............................................s-RRVEAMRELYQAIDKRR-RTGGMFTLSEL-GMKKLP.VRGVYIFIDKSERNF......LGRRGRIVRIGTHAVSEGSKSTLRNRLRNHAGLR-........DGTGNHRGSIFRLHVGRAVLERENAS.aALP.SWG....EGQD....APIHV..........RAHEVSMEQLVSDYLKK.L.EVL.VLDIDDTPSKHSLRAIVERQLIALCSESL-..IPIDRPSKAWLGLS...SPMRLIAESGLWNLRDV...G.R..AYDPQGQGSVRDLI------sld.......................
A0A0H1REI1_9HYPH/1-233               .............................................MSHLADLQAFYSILAELGRRTGEARPLRSEGERRRWP.RRGVYFFFEPHETRT.....tSGTGPRIVRVGTHALKVGGSATLSVRLNQHRGAIR........TGGGNHRGSIFRLLVGLALSQRDASI..AVA.TWG....DKKI....ERKVA..........APKEMQLEREVSQYIGA.M.PVL.ALEVPDEPGPDSLRGYIERNAIALLSGFNS..SEADKPSNHWLGYH...CPRDRVRRSGLWNNNHV...D.E..TYDSQFLGIMEQLMLQQ---asf.......................
A0A6B0TDV0_9EURY/1-236               .............................................MSRQDDMDRLYDLFEILEERVGGMQRLRECTGHMDWP.DRGVYFFFAADETRE......STDQLRLTRVGTHAVSSGSGTSLWNRLRTHRGAKSg.....tyEGGGNHRGSVFRKRVGEAMIERHDIH.nEYP.NWG....EGSS....AGRER..........RLAELELERQVSDYIRD.L.PFL.WISVDDEPGPESDRAYLERNTIALVSNYSK..ELIDSRDDEWLGNE...SPCEEIRQSGLWNVNHV...E.E..QYDSAYLDRLEAAVEETS--sp........................
A0A1T5M0V5_9FIRM/8-111               .................................rattssnivfsv-------------------------------------.---------------......-KVRRRIVRVGTH----TGHDNLKTRLYSHFRGK-........----NQRSSIFRRNIGRVYLNKDNKN..YLP.IWN....SSRN....NKSST..........-----------------.-.---.------------------------------..--------------...-----------------...-.-..--------------------lryiqellghrssktteiythlevla
A0A1I6HC64_9EURY/1-242               .............................................MDRSADLDRLYALFGRLEERVGGARRLADCTGYMDWP.DRGLYVFFAPGESRA......SSGQRRVTRVGTHAVSAGSSTTLWDRLKQHYGTGPgs...sahPHGGNHRGSVYRRRVGEAFVERYGLH.eRYP.DWG....ATSVpddrDRSEV..........RDEEYPLERRVSAFLRD.Q.PFL.WVDLDDEPGPDSDRAYVERNLVALVSNYDR..RPRDPRRSDWLGGY...ARSAKIRASGLWNVEHA...D.E..SYDPAFLDTLAAAVERTT--pp........................
A0A292YRE3_9BACL/2-109               .............................hnsanernyghlineg-------------------------------------.---------------......-----------------------------------........--------------------------..---.---....----....-----..........--LENELEAKISRYLRD.NiTFV.CFPVDEE----SQRLRLEEGIIATLNRH--..-PSFGPSSNWLGLN...SPLSEISSSGLWNRQGL...Q.-..--------------------gqplsdeelelvkwlar.........
A0A089JW76_9BACL/5-213               .........................ccnlheivnkmtrhhfpfed---------------------------------NVIP.RNGVYLLFETGEYGH......GAD--RIVRVGTH----TGPNQLRSRLKQHFVQE-........----NKDRSIFRKNIGRCLLNRDKDP..YTS.VWE....LDFT....TREAKlnng..hlvdPAYQSNIESRVSDYIQKhF.SFC.VLAIEDKP----ERLSLESRLISTLSLCD-..--ECAPSVQWLGMS...SPHEKIRRSGLWQVNEL..yK.E..PLNNQDFDRIEV--------lasesr....................
A0A316GJZ8_9RHOB/1-233               .............................................MPRQSDLDTFYWLLDDLEARVGGRRRLAECHGRLHWP.RRGVYFFFEPGEHRD.....aASTDYRVVRVGTHALTSKSRTTLWKRLGQHRGTTS........PPGGNHRGSIFRLLVGEALLNRDASL..SVD.SWG....QGSS....ASGEL..........RAKEREHEMKVSEYLGG.M.TLL.FVDVPDDPGRESGRGILERNSIALLSSYVE..PTSDQPSSHWLGHR...SGRERVRRSGLWNNNHV...D.E..AYDPGFLDVFEEMIAHTQ--vg........................
A0A1N6ZD04_9EURY/1-236               .............................................MGRRDDLDRFYQLMGNLEEQVGGTQKLKDCTGYMDWP.DRGVYFFFAPDETRA......SSDQLRVTRVGTHAVSEGSSTSLWNRLRTHRGAMSg.....tyEGGGNHRGSVFRKRVGEAIIDRDEYQ.eEYP.EWG....DGSS....AGREL..........RLEELEMERKVSEYNRD.L.PFL.WLNVDDEPSAKSQRSYIERNAIALLSNYQK..TAIDARSDGWLGKH...SRSEKICQSGLWNVNHV...E.E..NYDPNFLDQLERKIEETD--si........................
A0A1H3Y225_9EURY/1-241               .............................................MARAADLDRLYELLADLERRVGGTRKLKNCTGYMDWP.DRGVYVFLEPGETRA......SGQ-RRVTRVGTHAVSAGSSTSLWDRLKQHYGTGNrs...adhPHGGNHRGSVYRKRVGEAIIEKYGLH.dDYP.DWG....ERWStidrDRTEV..........RDEEYPLERRVSTYIRE.Q.PFL.WVALDDEPSPDSDRAFVERNAIALLSNVDS..ATLDPRPDDWLGHH...SRSRQIRASGLWNVAHT...E.D..AYDPRFLDRLERAVAET---gtr.......................
A0A7X8NAY3_9FLAO/3-209               .........................eicneihgifnelkeysfpf-------------------------------NEKEIP.KNGIYILFEKGEKFN......NL--KRIVRIGTH----TGDNQLQSRLKQHFVKE-........----NKDRSIFRKNIGRALLNAENDS..FLK.QWE....LDLT....TRANKkkys..eqidFKKQQTIEKKVSEYIQN.NfSFA.VFEVLEKE----QRLRIESRIISTVSNCT-..--NCKPSENWLGLS...SPKQKIKDSGLWLVNEL..wK.Q..SLSENELTELK---------rim.......................
A0A1W6LPZ8_9BACT/13-217              ............................clhdffnklprfrfpfd--------------------------------KQSLP.LNGIYVLFEKGERGH......CLD--RIVRVGSH----TGQNNLRERMREHFIRE-........----NKDRSIFRKNIGRALLNTRNDP..YLS.QWN....YDLT....SKKNRvrye..heidWKFQQSVESEVSEIIKD.TfSFS.VIHIDNRE----ARMKYEKKMIATIGKCS-..--KCEASDNWFGKN...SPENRIRQSGLWLKQGL...R.Q..A--PFSLDEFSQFIQK----vkv.......................
U5NDT0_9BURK/5-234                   ............................................e-QRLQNMRDFYHILEELQQKVGGRRVLANCNGRMHWP.QRGVYFFFEPGEYRS.....hSGDGDRIVRVGTHALNPNSRTTLWNRLMQHRGTVH........PLGGNHRGSIFRLLVGQSLIQRNGYQ..DYP.HWG....MGNN....APSEI..........RESERPLEREVSQAIGA.M.PFL.WLAVEDAPGPQSLRGCIERNAIAMLSNFHK..DAIDPPSENWLGKD...CDRETVRLSGLWNSNHV...Q.D..GYDPRFLEVMHNAVEQ----m.........................
A0A6G2FUB3_9EURY/1-242               .............................................MERSADLDRLYALFDRLEARVGGAKRLADCTGYADWP.KRGVYFFFAPGETRA......ESGQRRLTRVGTHAVSAGSSTALWDRLKQHYGTGArs...ddhPHGGNHRGSVYRRRVGEAFVERYGLH.dHYP.DWG....TPSVpdgrDRAAV..........RDEEYPLERRVSAFLRD.Q.PFL.WVALDDEPGPDSDRAFVERNTIALASNFDR..RPADPRRSDWLGGY...ARSAKIRAGGLWNVAHA...A.E..SHNPAFLDVLERAVERTD--pv........................
M0CEQ6_9EURY/1-128                   ............................................m-------------------------------------.---------------......-----------------------------------........-------------------RERDDLH.dVYP.EWG....EGSS....AEREI..........RLKETGLERRVTEYIGD.L.PFL.WLDVDDEPSPESDRAYIERNALALVSNYRT..DPIDQRAGDWLGMH...SPVPAIRRSGLWNINHV...D.E..SYDPVFLDRFEERIAETA--sv........................
A0A1W2DTW5_9RHOB/8-240               ............................................k-TRISDQKRFYDLLDSLEKRLGGARVLSDCHGRMDWP.QRGVYFFREPGENRN.....nTDLGPRIVRVGTHALKAGARTKLWNRLSQHRGSAQ........SGGGNHRGSIFRLLVGNALIERDKQC..-HS.NWG....EGSF....ATREI..........RQSELPLEQAVSKVIGA.M.PFL.WLPINDEPGPDSLRGYIERNSIALLSNHNRinDRLDPASDNWLGWL...CDRDRVKDSGLWNQNHV...N.E..KYDVVFLDTLETLIHE----lwg.......................
V4Y9T0_9ARCH/1-235                   .............................................MTRQDDLDSVYSLLDDLEATVGGKRKLGDCDGRMNWP.NRGIYFFFDPEETRS......EPDQLRLTRIGTHAVSEGSSTSLWNRLRTHRGPQRg.....tyEDGGNHRGSVFRKRIGEAIIEKDNLE.kEYS.EWG....VGSS....AGREL..........RMEELDMERRVSEYIRD.L.PFL.WVDVDDEPSPESDRAYIERNMIALVSNIDT..ESIDPRREDWLGHH...SPVMEIKQSGLWNINHL...T.E..DYQPEFLETFEGYIDRM---pg........................
A0A1T4XUI6_9CLOT/154-345             ...............................lprldwsiinsipy-------------------------------------.KNGIYIMFEKGENYH......GMD--RIVRVGTH----RGQDRLLQRLRDHFVKE-........----DADGSIFRKNIGRAFLKMASDP..YLQ.VWE....IDMH....NSENErnyg..hlinEGLETELEAKISRYLRD.NiTFV.CFPVDKEA----ERLRLEEGIIASLNRHS-..--SFGPSSNWLGLH...SPVPEIANSGLWNRQG-...-.-..--------------------llgqplsdeelervv...........
A0A1N6E3X2_9RHOB/2-234               ............................................d-NRLADLQRFYELMAELDSYIEGKHLLRDCHGRMNWP.MRGVYFFFEDGEVRG.....qSGNGPRVVRVGTHALKSGSRTSLWKRLSQHKGVAL........SGGGNHRGSIFRLIVGTALLERDGLT..-SE.SWD....NRKS...tAPREV..........RLAEQHIEQLVSGVIGA.M.PFL.WLDVGDDPGAESERGIIERGSIALLSNWRK..EPIDPPSSSWLGKY...CNRERIRSSGLWNSNHV...D.E..AYDPNFLDVLESRVEQI---rrr.......................
A0A098M902_9BACL/22-218              ...................................rhrfpfeddc-----------------------------------IP.RNGIYFLLEKGEYGH......D--ADRIVRVGTH----TGPNQLRSRLKQHFVQE-........----NKDRSIFRKNIGRCLLNRDKDP..YAS.VWE....LDFT....T-REAklnn.ghlinPAYQLTIESRVSDYFQKhF.SFC.VLGIEDKT----ERLSLESRLISTLSLCD-..--ECAPSVQWLGMS...SPHEKIRRSGLWQVNEL..yK.E..PLNNQDFDRIEV--------lasesr....................
C7NQW7_HALUD/1-236                   .............................................MSRRDDLDRFYELMDRLDDRVNGMQRLQDCTGYMDWP.ERGVYFFFADDERRA......ETDHRRLTRVGTHAVSAGSGTSLWNRLRTHRGATSg.....tyEGGGNHRGSVFRERVGEALIEREGLS.eEYP.HWG....DGST....AGRER..........RLDELDHERSVSEYIRN.L.PFL.WIKVNDEPGRDSDRATIERNAIALVSNFDR..QSIDPRDEDWLGHS...CPSPEIRRSGLWNVNHV...E.E..DYDPSFLDRLEAAIVETE--pp........................
A0A7D5DXD7_9EURY/1-242               .............................................MARQDDLDRFYGLLDDLEQRVGGTWKLKNCTGYMDWP.DRGVYFFLEPGETRT......STDQLRVTRVGTHAVSAGSSTSLWDRLKQHYGTGSgs...snhPHGGAHRGSVYRKRVGEAIIEKHDLH.dDYP.DWD....KRWSsidrERSEV..........RDEEYILERRVSTYIRE.Q.PFL.WVNLDDEPSADSDRAYLEQNVIALLSNFDE..QPIDPRGGGWLGRH...SQSQAIRESGLWNVNHV...D.E..RYDSGFLDLLENAINGTT--ps........................
A0A0G3V3A6_9ACTN/4-240               ............................................n-ERRTSVNLFYELIDKLSDRIGGARYLATSSGQDEWP.QRGVYFFFEHGELRE......GGEAPRVVRVGTHALAANSRTLLWSRLSQHRGTVGg.....snPGGGSHRGSVFRRHIGMAILGADSTMvkGRS.TWG....RGSN....ASASV..........RDGESKLEIAVSTVIRK.M.PFV.WLPVLDNAGPLSGRGAIEVGAISLLSNFKR..TPIDPPSESWLGRT...SDREKIRDSGLWNIRHV...E.D..QPSPGFIEALSSAIDQI---asp.......................
A0A2C8FCS1_9BACT/138-369             ............................................s-HRIDHLKRLYELLDILETRVGGKFLLHDSDGRMGWP.KQGLYLFFENGEERS.....eSGKGPRIVRVGTHAVSDGSKTTLWNRISQHKGIVK........SGGGNHRGSIFRLIVGEAIQQKDPTE..IVH.SWG....KGSS....APKDI..........RDNELPLECAVSDIIRS.M.PFL.FIDVPGISAKDNDRSLLEQNLIGLLSNYDR..ETLDPPSPNWLGRS...CPRNLIQCSGLWNSQHV...E.K..GYTPDFLDLLEKYILNT---ti........................
A0A1M4NEE5_9CLOT/152-348             .............................nglprldwtminripy-------------------------------------.QNGIYIMFAKGEYYH......GMD--RIVRVGTH----RGQDRLLQRLRDHFVKE-........----DADGSIFRKNIGRAFLKMASDP..YLQ.VWE....IDMH....NSENErnyg..hlinEGLETELEAKISRYLRD.NiTFV.CFPVDKEA----ERLRLEEGIIASLNRRS-..--SFGPSSNWLGLH...SPVPEIASSGLWNRQG-...-.-..--------------------llgqplsdeelervkwla........
A0A327XJT2_9RHOB/2-234               ............................................t-SRLADLHRFYELMAELDARTRGKRLLQDCHGRMDWP.QRGVYFFFEDGEMRA.....hSSGESRVVRIGTHALKAGSRTTLWKRLSQHKGVAR........SGGGNHRGSIFRLIVGTALLDRDELQ..-SE.SWD....NRQS...tAPREI..........RLAEQPIEQVVSGVIGA.M.PFL.WLDVGDDAGAESERGVIERGSIALLSNWRN..EPIDPPSDSWLGNY...CNRERVRKSGLWNSNHV...D.E..AYDPRFLDVLERRVEQM---gtr.......................
A0A343TLU9_9EURY/1-137               .............................................-------------------------------------.---------------......-----------------------------------........---------MFRKRVGEAMIERDGLH.dEYP.HWG....DGSS....AGRER..........RLAELEHERRVSEYIRD.L.PFL.WVDVDDEPSPESDRAYIERNAIALVSNYRK..DSLDPRDDGWLGRD...SPRNEISGSGLWNINHV...G.E..QYDTAFLNRLADGVEETS--el........................
A0A7W3MYG8_9ACTN/6-233               ............................................a-DRRRDTDRFYALLDELAERVGGPRRLKDCTEASGWP.QYGVEFFLEDGQVRA......GGGGLRVVRVGSHALRTTSKATFWTRLAQHRGPVSg.....anAGVGNHRGSVFRQHVGSALLETGDWP.aEVA.QTW....GQKD....VSPVQ..........RAAERPLERAVSDHIGA.M.PLL.WLDVPDLE----QRKSIRANAIALLSQRT-..GGIHPTTPGWLGLH...AKNDNVRTSGLWNSDFV...D.D..PYDPSFLDAMEACVKA----m.........................
A0A5B8FXY0_9RHOB/4-206               ...........................ckllhqffdamprlspdl-------------------------------CSANIP.ANGIYAVFEVDEEAH......GGN--RIVRIGTH----TGQGNLRGRLIEHLLKP-........----NKDRSIFRKHVGRAILAERNDP..ALD.QWN....LKLT....RRKARaehg..hrvdPLKMTAVETEVSQKLRA.R.--M.SFAVLPLSGGKEDRLAWEKRMLSTIAACP-..--DCRPSPIWLGLW...HPDPRIGRNGLWNIQG-...-.-..--------------------frgevlseddvrsft...........
A0A6B0SYR0_9EURY/1-242               .............................................MSRRDDLDRFYDLLGKVAARVGGPRRLKRCTGYMDWP.DRGVYFFLEPGESRS......ESDQSRVTRVGTHAVSTGSGTSLWDRLKQHYGTGSgs...sdhPHGGNHRGSVYRKRVGEAIIAKYDLH.eEYP.AWD....DRWSsidrDRSAV..........RDEEYILERRVSTYIRE.Q.PFL.WVDVDDEPSADSDRAYIEQNAIALLSNVAE..ETVDPRADGWLGKY...SRSREIRESGLWNVNHV...E.D..EYDPAFLDVFADAVKRTT--pp........................
A0A8T4H3B8_9EURY/1-241               .............................................MARADDLDRFYDVLERLDRRVGGARRLKNCTGHMDWP.DRGVYAFLEPGQYHE......DGV-RRVTRVGTHAVSAGSSTTLWDRLKQHSGTGDgs...dahPHGGNHRGSVYRKRVGEAIIENHDLH.tEYP.DWG....ERWStvdrDRTVV..........RDEEYLLERRVSTYLRE.Q.PFL.WMDLDDEPGPKSDRAVLERSVIALVSNAGR..EPIDPRPVDWLGRH...SPSAAIRDSGLWNVAGV...E.D..DYDPAALDLLETAVDATT--pp........................
A0A086YSC7_9FIRM/3-212               ........................eicerihhmlsnferhhfpfd--------------------------------ENEIP.LNGIYLVFEDGERSH......GT--DRIVRVGTH----TGENQLRSRLKQHFVNE-........----NKDRSIFRKNIGRALLQKANDP..FLK.QWE....WDLT....SREAKegll..slldVDRQKEVEEAVSVHIRQhL.SFV.VLQVASKE----ERLELEQKIISSISWCE-..--QCGPSPDWLGLY...STKQKIRESGLWLVNGL..yK.E..QMSRKELEMLEKMI------vtg.......................
A0A343TLU8_9EURY/1-75                .............................................MSRRSDLDRLYNLLDRLEANVGSKQRFKDCTGYMDWP.ERGVYFFFAEDETRN......STDQLRLTRIGPHAVSSGSGTSL------------........--------------------------..---.---....----....-----..........-----------------.-.---.------------------------------..--------------...-----------------...-.-..--------------------..........................
A0A0F7KSA1_9SPHN/7-231               .............................................MNRLDHLRRFYDLLDDLADRQRGPRPLADAVA-ALGN.ESGVYFFFEPEEVRS.....dSGTALRVVRVGTHALKPGASSTLRGRLRQHGGTR-........AGSGNHRGSIFRLLTGDALMRCGSEA..VCS.TWE....GKP-....---AN..........KLLEAPLELAVSLRLAL.T.RVV.WLRIDDPPGPGSQRGWIERNSIALLSNHGK..TQLDPPSADWLGQH...SSRPLVRSSGLWNQRHV...E.E..RYDPAFLDDLELLIG-----dhr.......................
A0A1I7LTD0_9BURK/164-392             ............................................p-DRLSHYNRFYNLLWRLQQIPGQMIPFNDFEG-KNLP.KAGVYFFFDGRESTRf....fHHETFRVIRIGTHGVSKGSKSLLWQRLRTHRGND-........DGSGSHRSSIFRLHVGNAILASQKKE..-LT.SWG....VGDN....ASKEI..........RDGEVQLESEVSQYLRD.L.RVA.YLPVFDEASVDSDRSYIEKNSISLLTQGG-..-AIDLPSANWLGNF...SNSKNVRNSGLWNVNYV...G.D..NYDPEFLNVFEKLIAKYE--kg........................
A0A087S115_9ARCH/11-165              krnkerqkeegskfgrgikketlvanktkdkqddskrtsaqvgka-------------------------------------.---------------......-----------------------------------........--------------------------..---.---....----....----Vnls...hlrnISLEKKIETQVTDLLQN.TfSFK.YLIIQGQE-KRMGSSGIESRLIGTVSECK-..--ECQPSINWLGNN...SPKSKIRDSGLWLYQHL...S.N..--------------------ppisesdkkdlvifhkhtkew.....
A0A2I8VMF9_9EURY/1-242               .............................................MARRNDLDRFYDLLDDLAHRVGGTRKLKNSTGYMDWP.DRGVYFFLEPGETRD......STGQLRVTRVGTHGVSEGSSTSLWDRLKQHYGTGSgs...sdhPHGGNHRGSVYRKRVGEAIIEKHDLT.dDYP.DWD....ERWSsigrERSVV..........RDEEYILERRVSTYVRE.Q.PFL.WVNLDDEPSADSDRAYLERNAIALLSNFEK..RSIDSRGDGWLGRY...SRSREIRDAGLWNVNHV...G.E..RYESGFLDLLETAVDDTT--ps........................
A0A4U7F544_9EURY/1-242               .............................................MTRRDDLDRFYSLLDDLEQRVGGTRKLKTCTGYMDWP.DRGVYFFLEPGETRA......STDRARVTSVGTHAVSEGSSTSLWDRLKQHYGTGSgs...snhPHGGAHRGSVYRKRVGEAIIEKHELQ.dDYP.DWD....KRWSsinrERSVV..........RDEEYILERRVSTYIRE.Q.PFL.WVNLDDKPSADSNRATLEQNAIAHLSNFGK..RPIDQRGDEWLGRY...SQSREIRESGLWNVNHV...E.E..NYEEEFLELLEQALNNTT--pl........................
A0A0Q5IU45_9DEIO/1-221               .............................................------MRHFYTLLDDLEQRVGGRRLLQDCTS-KGWP.NRGVYFFFEPGEQRT.....vTGEGARVVRVGTHAVSAGSKTSLWNRVSQHRGKVG........DGGGNHRGSIFRSHVGSALLARDGLT..-LA.SWG....VTHK....TELAD..........KQAEHDHEQRVSRTLGQ.F.GVL.WLAVDDVPSKDSERAFVERNAIALLSAVN-..GGADPASETWLGRW...AQAPAIRQSALWNVRHV...D.D..RVDPEFLGVFERLVRA----h.........................
K4LF01_THEPS/39-227                  .....................................lprydwsf-------------------------------KRKDIP.ANGIYLFYEKGENRS......DGT-QRIVRVGTHA----ADGRLPGRLIHHYR---........---GNRYSSVFRWHLGRALLRLQNAPrqVIE.TWE....IKNG....P----..........--KMPEVEDLVSRYMSSsF.QFS.CLAVPDKD----ERLKLEAWLIFILSTCS-..--SCSPSAHWLGLW...SPEALIRNSGLWNVDHV...P.AfvGQGTKLRDRFEELIER----qlk.......................
V4XCU0_9ARCH/1-192                   .............................................MERNALLDRFYSLLDDLERQVGGKQRLKDCDGYMDWP.DRGVYFFFASDEHRG......DGDHLRLTRVGTHAVSTGSGTTLWNRLRTHRGALSg.....tyEDGGNHRGSVFRERVGEALVERHGLH.dEYP.EWG....EGSS....AGRDR..........RLAELELERRVSDYIRE.L.PFL.WVDVDDEPGPGSDRAYIERNAIALASNYGR..SR------------...-----------------...-.-..--------------------sipgatg...................
A0A1H3GLJ0_9EURY/1-236               .............................................MSRESDLHRLYRLLTDLEDRIGGKQRLGDCTGYMDWP.ERGVYFFFSHDEHID......TGDQHRLTRIGTHAVSAGSGTSLWNRLRTHRGANSg.....tyGGGGNHRGSVFRKRVGEALIERHDLH.dEYP.YWG....EGSS....ADRDR..........RLDEHEHEQRVSERIRD.L.PFL.WVDVDDEPGPDSDRAYIERNAIALVSNFEK..DALDRRDDDWLGKE...SPRHEIRGSGLWNINHV...E.E..DYDPAFLDRVAEAVENTT--pa........................
A0A1M4ZHL2_9CLOT/141-353             ...................eedhcyllhkifnsmkkysfsnvdki-----------------------------------KV.KNGIYVILDKYQYYC......GMN--RIVKVGTHI----NQGRLKNRLLDYASNK-........----NKSSSIFRKNIGRAMLNAYNDP..YIS.IWN....IDFN....IDKNKkqys..nlrdKKKEREIENYIDDYMKKyL.QIV.CFEVINKP----LRLRLEEGIISTLNKEK-..--SFKDSINWYGKY...RAIPKMNSNELWIAKE-...-.-..--------------------ligeplsyeevdfigslcdksk....
A0A4R6KM88_9ACTN/3-229               ............................................t-GRQADLDRFYRLLAQLVEASRGLRRLRECTV-TSCP.SHGVYFFFEPGENRI......NGS-SRVVRVGTHALTATSQTTLWTRLKQHRGHVGg.....vrPGGGNHRGSIFRHHVGTALLATEDWP.sSLH.ISW....RSRH....VDHSA..........RTAEYPLEKAVSDYIAA.M.PML.WCAVTDRG----VRSAVERNSIALLSCRT-..GGHDLPSAAWLGRH...ADSQKLRTSGLWNVNHV...D.E..PYDRSYLDVLEGLVEST---g.........................
A0A1I5VCJ6_9FIRM/155-352             ...............................lprldwtmidqipy-------------------------------------.SNGIYVMFEKGESYK......GMD--RIVRVGTH----RGRGRLKTRLRDHFLKE-........----DADGSILRKNIGRAFLNAARDP..YLK.VWE....IDMH....ISENVrkyg..hlvnKHFETELERKITGYLREnV.TFI.TFPVEDEA----ERLRLEEGIIATLNRSS-..--DFRPSNSWLGLS...SPVTEIAQSGLWNRQGL...D.G..--------------------kplsdeelervkwlirfg........
V4GQU4_9EURY/1-236                   .............................................MGRRDDVDRLYDLVADLTGRVGGTRTLDDCTGYMDWP.DRGVYFFFAPDERRE......AGDHPRLTRVGTHAVSAGSGTALWDRLRTHRGATRg.....syEGGGNHRGSVFRRRVGEALIEREGLG.eAYP.HWG....EGST....AGRER..........RLDELPLERRVSDYLRD.L.PFL.WLNVDDEPGPESDRAYLERNAIALVSNYRR..DAVDPRPGGWLGRN...SRSRKIRESGLWNVNHA...D.E..AYDPAFLDLLGERIEETD--pv........................
A0A838ZU95_9FLAO/1-213               ....................mtdiydyiheyfnnqkrysfpydrk------------------------------TLKDLTD.SNGLYVLFENGEKYN......GLD--RIVRIGSH----DGNDRLIKRLGNHFNSK-........----LHRGSVFRKHIGRCFLNIAEDN..YLE.HWN....RPFKs..rAEKEIhgk....yvdLEYEKKYEDKVTEHIHK.N.--L.SFAIIPKVYDREKRDRIEKGLISSLNQSD-..--KKICSVNWLGNY...HPDKRIRNAKIWNIEYL...K.H..--QPLDLKEFKELI------ek........................
A0A7D5GLP3_9EURY/1-236               .............................................MTRVDDVGHLYRLLVELEERVGGPQKLKECTGYMDWP.DRGIYIFFTPDESRA......SESQPRITRIGTHAVSEGSSTSLWDRLRTHRGAKRg.....tyEGGGNHRGSVFRKRVGEAFIERDELH.dEYL.WWG....EGSS....AAREQ..........RLAELELERRVSDYLRE.L.PFL.WVNVDDEPSADSERAYIERNMIALLSNYRR..NSIDPRSRDWLGTY...SRSEKIRESGLWNVNHV...D.E..EYDPAFLNHLSRQIAETS--av........................
A0A133UGG7_9EURY/4-233               ................................kcewlhekleklp-------------------------KIQYPFEKSSLP.KNGIYFFYEKGETWG.....hDGNKPRIVRVGTHK-----SGNFRSRISEHFLFEEerkmdfdqNDSKPSDRSIFRKNIGRALLNKDDND..YLK.VWNidfiKRKNreehASKRN..........ISKEREIERKITEILRE.NfSFR.FIAFEGGT-NIMGKEGLESNLIGTLGQCS-..--ECKPSKDWLGNS...SSKPKIRESGLWLIQHL...K.D.sPIDEADKKVISDSIKK----sgqk......................
A0A1I2SQW1_9EURY/4-245               ............................................t-TRAADLDRLYDLFDELAARVGGPRRLADCHGRMDWP.DRGVYFFFAPGETRA......SSGQRRLTRVGTHAVTEGSKTTLWDRLKQHYGTGDgs...sahPHGGNHRGSVYRLRVGEALVEHHGLA.dAYP.DWG....TSRIpadrPRAAV..........RDEEYPMERWVSSYLRH.Q.PFL.WVGVSDAPSSTSDRARIERNVIALASNYGG..PVADARSTDWLGRH...SPNAEIRAGGLWNVEHA...D.E..SHDPSALDTFAEYVADA---epl.......................
L0F3V7_DESDL/147-263                 ......................kaihqlfnmmprldyqrildisf-------------------------------------.ENGIYVMFEKGQKYG......--ELDRIVRVGTHTVD----GRLKARLVDHFIRK-........----NKDGSIFRKNVGKALLARSDDP..YLN.IWS....LDTS....KPDN-..........-----------------.-.---.------------------------------..--------------...-----------------...-.-..--------------------kplidelkqakvttk...........
A0AA43XJN0_9CLOT/57-264              ....................deissqgeelhrmfneavplhwnei---------------------------------DKLPyNNGIYIMFERGELYK......GRN--RIVRIGTHLR----PDRLIKRLKNHSINK-........----NANGSIFRKNIGRALLHKKEDP..YLK.IWD....KNTS....DKE-Ikeey.nhlidKKKEKELEEIISDYLKN.NiTFV.CFPVNTEK----ERLRLEEGMISVLNHTE-..--DFQPSTSWLGLS...SPVEEIKSSGLWNCNGL...-.-..--------------------ngalltdeemkriq............
A0A830GJF7_9EURY/1-47                ............................................m-------------------------------------.---------------......-----------------------------------........----------YRKRVGEAIIEKHNLH.dDYP.DWD....KRWSsidrDRSEV..........RDEEYILER--------.-.---.------------------------------..--------------...-----------------...-.-..--------------------v.........................
A0A8J7SBN7_9RHOB/2-233               ............................................t-DRLEDLRRFYALMDELERRVGGKRILAECHGRLSWP.ERGVYFFFEEGEDRS.....gSGRGPRVVRVGTHALKAGSGTTLWKRLSQHRGQAR........SGGGNHRGSIFRLIVGTALMARDGHV..-SP.NWD....NRHS...sASREV..........RGAELTMERAVSVVIGA.M.PFL.WLPVEDDAGPQSGRGIIERGSIALLSDWGK..EPIDPPSDRWLGHH...CNRPRVRGSGLWNSNHV...D.E..SYEVSYLDALERYIQN----aga.......................
A6P101_9FIRM/161-348                 ...................................tweeigavpf-------------------------------------.RNGIYLVFEAGETYH......--GMPRIVRVGTH----KSSDRLRQRLRDHFVRE-........----NHNGSIFRKNIGKALLNQTGDP..YLA.VWS....LDTSrppcKGMED..........PHREREVEQEVSRYLRThM.TFS.VVEVETRE----QRLRLEEGIIASLHQAE-..--DFQASSSWLGRF...SPEKEIRESGMWLKQG-...-.-..--------------------ldgvpladeelealecrls.......
D4GVX1_HALVD/1-236                   .............................................MARREDITRLYELLDELEQTVGGKQKLKDCTGYMDWP.DRGVYFFFASDEHRD......AGDQLRITRIGTHAVSERSSTSLWDRLRTHRGAKRg.....tyEGGGNHRGSVFRKRVGEAFVERDSLN.dEYP.HWG....EGSS....AKRER..........RLDELEMERRVSDYLRD.L.PFL.WLNVDDEPRAESQRAYIERNTIALLSNYQR..EAVDARSDNWLGNH...SRSKKIRESGLWNVNHV...D.E..DYDPEFLDLLRDQIEETS--pv........................
A0A830GIQ2_9EURY/1-94                ............................................m-------------------------------------.---------------......-----------------------------------........--------------------------..---.---....----....-----..........-----------STYIRE.Q.PFL.WVDVDDEPRADSDRAHIEQNAIALLSNFEG..QTVDPRDDGWLGKY...SRSRAIRESGLWNVNHV...E.E..QYDPDFLDLLEDAVEDTT--pl........................
A0A8J7YHT3_9EURY/1-233               ............................................m-IRADDIDRFYALLSELEEQVGGKQRLGECTGYMDWP.NRGIYFFFAPDEYR-......-GQQLRLTRVGTHAVSQGSQTALWDRLRTHRGAQRg.....tyEGGGNHRGSVFRKRIGEAIIERDGLH.gEHS.DWG....VGSS....AGRDQ..........RLTELELERRVSDYIRD.L.PFL.WVKVDDEPGPDSDRAYLEQNVIALLSNHQC..TPIDER-EQWLGQY...SRSEKIRDSGLWNVNHV...D.E..GYNPEFLSVLQEQIEQTS--pp........................
A0A9E8M1Z7_9BACI/150-346             ................................fnelprldwtmik----------------------------------QIPyQNGIYIMFEKGEEFH......GMD--RIVRIGTH----RGPNRLLKRLRNHFVRE-........----RSRGSIFRKNIGRVFLKMDLNR..SLQ.QQE....RDSQk..fASESKyas....ftrEKFTTELEEKISRFLRD.NiTFV.CFPVDEK----SDRLRLEEGIIASLNKH--..-PTFGPSKNWFGLN...SPIPAIVKSGLWNKQGL...Q.-..--------------------gkplsekelervkwl...........
A0A1H6C137_9EURY/1-236               .............................................MARREDIDRLYALLDELEQTVGGKQKLKDCTGYMDWP.DRGVYFFFASDERAD......AGDQLRITRIGTHAVSEGSRTSLWDRLRTHRGANRg.....tyEGGGNHRGSVFRKRVGEAFLARDSLD.dEYP.HWG....EGSS....AKRDR..........RRRELELERRVSDYIRD.L.PFL.WLNVDDEPSAESRRAYIEQNTIALLSNYQR..EAVDARSDGWLGNH...SRSEKIRKSGLWNVNHV...D.E..EYDAAFLDDFADAVEETT--pp........................
L0IAF7_HALRX/1-236                   .............................................MGRRDDLDRLYDLLDRLDDRVGGAKTLTDCTGYMDWP.ERGLYVFFADGETRD......GTEQPRLTRVGTHAVSSGSGASLWERLRAHRGVNSg.....tfGGGGNHRMSVFRKRVGEAMIHHDGIQ.eELS.NWG....EGNS....ANRDT..........RHDEHDHEVRVSEYIRD.L.PFL.WIDVDDEPGPDSERAYLESNLIALVSNYKT..EPIDPRASDWLGGH...CPSEPIRNSGLWNVNHV...D.E..AYDSNFLTLLETRIDETE--pi........................
A0A5E4X442_9BURK/1-242               .............................................MDRLDDLQRFYAILAQIEARLGDKLKLRDCHQRIGWP.ARGVYFFFEEGEHRT.....dSGVGLRVVRVGTHALGQ-SKATLQNRLSQHRGIIR........DGSGNHRGSIFRLLVGSAIKERDGFA..EPR.SWG....IGGD....YRQAAtrvgmaseavKEAEILLECAVTSHIKA.M.PFI.FVAELDPPGPESMRGYIERNSIGLLSNYRR..DALDIPSARWLGRH...SDREKVRESGLWNNRHV...D.E..GYDPGFLNILKRLAQET---pll.......................
A0A7I9VKT1_9BACT/1-240               .............................................MSRLQDIQRLYEVLADVQHRLGGPLSLRGCHGRMTWP.TRGVYFFFEPGEERS.....tSGIGPRVVRVGTHALTSTSTRTLWNRLSQHRGVAK........SGGGNHRGSIFRLLVGEALLRRDQAH..-IE.TWG....VGGS....PRDVArarnlspgtvIEVERSTEVAVSGIIGA.M.PFL.FVRVDDPPGPESMRSVIERNAIALLSNLAK..DPVDPPSSGWLGHH...SGHERVRGSGLWNNRHV...E.G..QYEPSFLDLLARV-------gsgrs.....................
C6A4B9_THESM/8-232                   ............................lheileelplikypfrl---------------------------------ESLP.LNGIYFFYEKGEIWG.....hGGEKLRLVRIGTHK-----GNNFRNRIAEHFLINEkkm.dfgrNNPKPSDRSIFRKNIGRALLNKNKDP..YLK.VWE....IDFT....PRTNRdkys..hlrdIEKEKSIEKQITEILRK.N.FFFrFIIIEDEK-ERIGSKGLESKLIGTVSKCT-..--ICKPSMNWLGNY...SPKKEIRTSGLWIIQHL..nA.E..GITEEDMPVIEKLIRKTK--tw........................
S0G1J8_9BACT/3-211                   ........................keceklhdlmqglerhgfpfd--------------------------------ESKIP.SNGIYCLFEVGEEGH......GGK--RIVRIGTH----TGANQLRSRLRQHFFNE-........----NKDRSIFRKNIGRALLNRNNDP..FIE.TWE....INLT....TRKAKnkys..sfidFGYQKSIEAQVSRYIQN.NfSFS.VFEVTEKE----ERLQIESKMISTVSRCE-..--GCKASKEWLGNS...SPKHKIVKSGLWLVNEL..yK.T..PFDASGIDHLSKVIR-----g.........................
A0A126V695_9RHOB/1-218               .............................................-------------MDALEHGLGGKRTLAQCHGRLPWP.ERGVYFFFEAGEERA......-TSGPRVVRVGTHALKTGSKTKLWNRLSQHRGSAR........SGGGNHRGSIFRLIVGTALMERDGHA..-SA.SWD....DRQS...tAPREV..........RAAEHPFEQTVSTTIGS.M.QFL.WLPVNDEAGPKSARGIIERGSIALLSNWEK..AAIDPPSKNWLGHH...CNRDRVRTSGLWNQNHV...N.E..EYDHWFLSDLEQFVKQA---gan.......................
A0A1G9J3N1_9RHOB/1-87                .............................................-------------------------------------.---------------......-----------------------------------........--------------------------..---.---....----....-----..........-----------------.M.PFL.WLEVNDEPGPDSLRGYIERNSIALLSNSGK..APLDPPSFDWLGRS...CNRNRVRASGLWNQNHV...E.E..CYDPAFLDTLERLIHAE---tea.......................
A0A4R4RXE1_9ACTN/3-230               ............................................e-DRRLAIDRFYAILDELAERLGGPRLLKDCTRADGWP.QYGVEFFLEDGQVRS......GENRLRVVRVGSHALRATSRATFWTRLAQHRGPVSg.....skAGVGNHRGSIFRQHVGSALLQTGQWP.aEVQ.MSW....GQRK....VSPAQ..........REAEYLLERAVSDRIGA.M.PLL.WLEVPDRE----QRISIRANSIALLSRCT-..GGTHPISPGWLGLD...AGNENVRRSGLWNSEHV...D.D..PYDPAFLDVMEAHL------kmg.......................
A0A4Q8R341_9BRAD/3-234               ............................................s-QRSADLQRFYSAIERLLKSLGGPRLLGDLAGRLNWP.RRGVYFFMEDGEIRS.....dTGSGPRIVRVGTHALNPASSTKLWTRLSQHRGRVR........TGGGNHRGSIFRLIVGTAFMARDGHV..-CG.SWG....VGST....ASADI..........RAGEVPLESKVSQFIRK.M.PCI.WIEVDDDPGPDSLRGYIERNAIALLSNYRK..ECVDPPSLGWLGHC...CDREKVRKSGLWNSNHV...D.E..RYDPGFLDCLDAHVLA----mgqr......................
A0A6N7ILL2_9FIRM/1-227               ............................................m----RDLERFYAALNTIREHVGGERRLSECSGRMGWP.RRGVYFFFEPGENRC......SGAGLRVVRVGTHAVSSGSGTTLWDRLRTHRGVL-........GGGGNHRASIFRLHVGTALLARGDYP.dAVRlSWG....RGSS....APKEV..........RRAEHGLECAVSEYIGK.M.PFL.WLKVDDEPGPASMRKYIERNAVALLSAASR..LRIDLPSEGWLGHS...SRHEAVRVSGLWNVDHV...F.E..EYDPDFLDLFERL-------aggn......................
A0A830GN08_9EURY/1-236               .............................................MERREDINRLYGLLDELEQTVGGKQKLKDCTGYMDWP.DRGVYIFFAPDEYRE......SGDQLRVTRIGTHAVSEGSSTSLWNRLRTHRGAKRg.....tyEGGGNHRGSVFRKRVGESFVECDGLY.dEYP.QWG....SGST....ANREL..........RLDELEMERRVSDYLRE.L.PFL.WLNVDDEPSADSQRAYIERNTIALLSNYQR..DAVDARSDDWLGQY...SRSEKIRESGLWNVNHV...D.E..AYDPAFLDDIAAAIDDTD--sv........................
A0A1T5KYC7_9FIRM/3-210               .........................ryceilhkqlsnlqrysfpf-------------------------------DKNPIP.KNGIYILFEKGETGH......GVD--RIVRIGTH----TGDNQLVSRLKQHFIKE-........----NKDRSIFRKNIGRSILNKNKDN..YLE.RWEw..dLTSR....KNREKymh....lvdLEYQMSIEKKVSKYIRE.NfSFA.VISIENK----DSRLNIESKLISEVSNCS-..--KCISSSNWLGNY...SPKNKIRQSGLWLVNEL..yK.D..GFSKTE--------------fekflklin.................
A0A133VNH2_9EURY/1-233               .............................................MSRKEDVDRLYEILNELENAVGGKRKLENCDGRMDWP.RRGVYFFFDPREERK......STDELRVTRVGTHAVSRGSETTLWDRLKTHRGTLSg.....kyAGGGNHRGSVFRKEVGRAIIAREGGE.qKYP.DWG....EGSS....AEPEV..........RKRELDMEKEVSKHIRN.L.PFL.WIKINDKPGAGSKRAFVERNSIALLSNFGK..EPIDPREQAWLGNH...SPKRKIRESGLWNVDYV...D.E..SYKRGFLEEMRGIVR-----sl........................
A0A1B6Z4S8_9SPHN/1-218               ........................................mgppt-------------------------KFSELK-LRSLP.QRGVYFFFEEGELRS.....gNRLNKRIVRVGTHALRAGSKSTLATRLGQHRGSQ-........-RGGNHRGSIFRLLIGQALLAQSKNA..DCP.SWG....LKGQ....RRHAAtvlgktseglRALEKPIEIRASERIGG.M.SVA.ILEINDEPGKESHRGYVERNAIALLSEAKR..GGLDPPSKNWLGYS...SNRPLVQNSGLWNQNHT...T.D..PVDPQFINQFSALV------gprh......................
A0A135L110_9BACI/54-251              .............................nglprldwtminripy-------------------------------------.QNGIYIMFEKGESYH......GMD--RIVRIGTH----RGQDRLLKRLRDHFVKE-........----DADGSIFRKNIGRAFLKMTSDP..YLQ.VWE....IDMH....NSENErnyg..hlinEELETELEAKIGRYLRD.NiTFV.CFPVDEEA----ERLRLEEGIIASLNRH--..-PSFGPSSNWLGLN...SPMSEIANSGLWNRQGL...Q.-..--------------------gqplsdeelerikwlar.........
B8EPP5_METSB/3-234                   ............................................s-QRLSDLQKFYSIIARLEKGLGGARTLGSASGRLTWP.KRGVYFFMEDGEVRS.....eSGSGPRIVRVGTHALKTASGTRLWTRLSQHRGRLG........SGGGNHRGSIFRLIVGTALMARHGHE..-YP.TWG....SGQS....ASADI..........RAGEVELEREVTRFIGA.M.PFV.WIEVDDEPGADSMRGYIERNAIALLSNFGR..TPVDAPSEGWLGHD...CNRERIRKSGLWNSNHV...D.E..VYDPAFLECLERHVLAME--av........................
S7TJK2_9BACT/172-401                 ..........................................ngl---NSDLDRFYAAVADLEKGLGGRRTFGECSGRMDWP.DRGVYLIFEPGEFRS......DGVTPRVVRVGTHAVSVAAKSTLWSRLRAHRGTL-........QGSGNHRASIFRLHVGRALAQRDPSL..MVE.TWG....VGQS....APKAV..........RKGEERLERAVSEYIAR.M.CVL.WLNIDDAPGRGSDRAYLERQIIGLLSADG-..RLADPSSENWLGRG...SFNTRISDSGLWNLDYV...L.F..DHESEMLDRFEAYVAAT---vnk.......................
A0A542LV36_9BURK/353-586             ...........................................ag--RSAHRTRFGELMRRLMTGADQGLPLARLLEGGRLP.ERGVYFFLDPTTSNE......-QDQWRICRVGTHAVSLGSKSTLRARLRAHLGTR-........SGSGNHRGSIFRLHVGNALLRRDQRE..-IA.TWG....IGSV....APPALrts....evlREAEARHEQQVSNYIGQ.L.PVL.WVAVPDEASPASERSIIERNAIALLSQDA-..QRSVMPANGWLGEH...SPRREIRESRLWNLNYV...D.D..DYNPDFLAVLERSVART---las.......................
A0A5N8YPT7_9CHLR/2-208               ...........................................sy--------RNYSDIHQILEPLKDYRSFEDAE--PDLP.ENGIYFYYTKGERFKtllddnRRSSPRITRVGI----ATADGNLPERIKTHYRAY-........------GSSIFRDHIERALKKRYKIR..-LD.TQP....KRRS....A----..........----DWWQGEITKYLEQ.N.--C.WFKVVETGSA-DEANSWETSLLATLAPYS-..--YQFCSSSWLGRWwkgTKSDRISEYGMWNIQKIlqfD.E..EFDDSRLSSFNDLIRN----q.........................
A0A0F7JUI3_9DEIO/1-185               .............................................-------------------------------------.---MYFMYEPGEDRA.....vTGSGPRVVRVGTHAVSRGSRASLWTRLAQHRGSR-........AGSGNHRASILRRHVGEALIARGDFV..-VP.SWG....TPRG....T-PEG..........RTQERPLEEEVSRRVGA.M.QVL.LLPIPDPPGPDSERALIERGVIGLLSQHG-..---DPASSDWLGRH...SPTNEIVRSGLWNVRHV...H.T..TPPPDLLGILERLVSA----vpv.......................
A0A418X016_9BURK/2-236               ..........................................rnl---LSDLDQFYTLLTRLEAA-GQGEHLGSYSGRARFP.LRGVYFFHEPGEYRR.....sHPNSPRIVRVGTHAVSANAKSTLWQRLRTHCGTR-........AGGGNHRGSVFRRHIGAALIARDGLS..-LP.TWG....VGQA....APPRLres....vtnQLAEAACEREVSAYIGA.M.PIL.WVDVPDAPGPTSERAFIERNAIALLSQVG-..MSTESASRSWLGLH...SPRSEIRSSRLWNVDYT...G.Q..TYDPRFLNVLATAVERTV--kq........................
A0A1D9MAS9_9RHOB/2-232               ............................................s-SRVEDIMRFYDILKMLEGRQGTIRTLPESAS-RDCP.LRGVYFFFELGEQRS.....gSGDGARVVRVGTHALKPGSKTTLWTRLSQHRGALR........SGGGNHRGSIFRLLVGSALIARDGLS..-CP.TWD....TQRS...nASSPV..........RAAEIELERLVSRTIGA.M.PVL.WLSVDDDPGAESERGVIERGAIALLSGWGQ..TEIDPPSANWLGHA...CTRVKVRRSGLWNNNHV...D.E..AYDPAFLDVMERRVLA----tpf.......................
A0A7X0G2Y0_9ACTN/6-232               ............................................d-DRRADTDRFYGLLDELAERLGGPRLLRDCTQETGWP.QYGVEFFLENGQVRA......GGDRLRVVRVGSHALRATSQANFWTRLAQHRGPVDg.....akAGVGNHRGSIFRQHVGSALLQTGHWL.aEVA.ESW....GQKE....VSPPQ..........RVAEHHLEEAVSDHIAT.M.PLL.WLEVPDRE----QRKSIRANSIALLSQRT-..GGIHRTTPSWLGLC...AKNEKVATSGLWNSDHV...D.D..LYDPSFLDNMEACVR-----l.........................
A0A8J2VND7_9RHOB/1-238               .............................................MSRLEDLTRLYSLLGRLETA-GGKRTLNGLGTTRDWP.RRGVYFFFESGEERS.....eSGTGPRLVRIGTHALGAGAQSTLRQRLRQHGGRS-........AGGGNHRGSIFRLLVGEALLTRDACP..SCL.SWG....VKGD....IGKAAallarsrielSALEAPVEIAVSTYLRA.M.PFL.WLSVDDDPGPDSLRGVIERNSIALLSNFNR..PPLDPPSDDWLGRL...SGREKVRRSGLWNQRHV...D.E..DYDPAFLDVLEDVISR----a.........................
Q2IEP0_ANADE/1-111                   .........................................mtts-------------------------------------.---------------......-----------------------------------........--------------------------..---.---....----....PTPEM..........RASELPLEQLVSEYLAS.M.RVL.WIEADDTPGPNSMRAYIEAHAIALLSEAA-..-TAEPASSGWLGHH...AADEAIRRSGLWNVKHV...G.R..SFDPAFLDEFQRLVAHT---psv.......................
A0A1W1UWI7_9DEIO/4-233               ............................................t-EQTQAIRHFYTLLDDLEQRLGGRRLLKDCTS-KGWP.HRGVYFFFEPGEQRT.....vTGEGARVVRIGTHAVSANSKTSLWNRLSQHKGKVR........DGGGNHRGSIFRSHVGSALLARDGLT..-LA.TWG....IGSS....AGQTV..........KQAEHEHEQRVSQTLGQ.F.GVL.WLSVGDAPGKDSERAFVEQNAIALLNNVN-..AGTDPGSETWLGRQ...AQAPAIRRSALWNVRHV...D.D..RVDPEFLSVFERLVRGH---dav.......................
A0A1D2YT16_9BACI/12-209              ...............................fnnlnrfyfpfneq----------------------------------LIP.QNGIYILFEKGERCN......GLD--RIVRIGTH----TGNNQLRSRLIQHFIDE-........----NKDRSIFRKNIGRALLNMRNDD..YLK.VWE....LDLT....SKKNKqkyn..slvdKDYQNKIEIEVSKIIQD.N.-FS.FVVFEEND--KENRLFLESKIIAEISKCS-..--NCKPSSNWLGKY...STKEKIRESGLWQVNNL...Y.-..--------------------kkgfseqefiqfknrf..........
A0A1W1VNR9_9BACT/6-208               ..........................lemhqllsererfyfpfkk-------------------------------NIDRIP.NNGIYFLFEKGETYK......EFD--RVVRVGTH----NGPNRLSTRLNQHFLIP-........----KKNGSIFRKNIGRCFLNKEQNP..YLK.YWE....IDTTs..rLSRKVnen....fidNIFEKQLEERISHYIQN.NfSFC.VLQINNKD----ERLFWESRMISTLAKAK-..-DI-EASQEWLGRH...STKEKIRVSGLWQVNEL...Y.-..--------------------kdcltetefdqik.............
A0A927MN27_9ACTN/1-85                .............................................-------------------------------------.---------------......-----------------------------------........--------------------------..---.---....----....-----..........-----------------.M.PFL.WLEVDDPPGPTSDRGRIKAGAIALLSNFDR..PVCDGPSEGWLGND...G-SPTIRESGLWNVDHV...D.E..VPDPAFLDLLESHLKRQ---sp........................
A0A3N6LZU7_9EURY/1-236               .............................................MSRHSDLDRLYDLLNRLETNVGGKQRLKDCTGYMDWP.DRGVYFFFAEDETRD......AADQLRLTRIGTHAVSSGSGTSLWNRLRTHRGANSg.....tyEDGGNHRGSVFRKRVGEALIERDGLR.dEYP.HWG....DGSS....ANRER..........RLAELEHERRVSEYIRD.L.PFL.WIHVDDEPSPQSDRSYIERNAIALVSNYRK..DSLDPRSGGWLGRD...SPRSEISDSGLWNINHV...G.E..EYDTAFLDRLADAVADTS--al........................
A0A5C8JZV3_9ACTN/1-210               .............................................--------------------MGGTRRLFNCSAASGWP.QRGVYFFFEDGETRT......DGNRPRVVRIGTHALTTTSHTTLWTRLAQHRGPIDg.....tnPRGGNQRGSIFRRHVGTALLATGHWP.sEIA.QSW....PKNH....VTSQQ..........RQAERPLELAVTAQIAA.M.PLL.WLDVPDRD----QRGTIEANAIALLSQRT-..GAVDPPSPGWLGLH...TANPKVRSSGLWNSNHV...D.D..RYDPSFLDDIALCLK-----shsr......................
A0A6B0VTL1_9EURY/1-236               .............................................MTRSEDINRFYGLLEDLEQNVGGKQKLKDCTGYMDWP.DRGVYFFLAPNETRD......SSDQRRITRIGTHAVSEGSKASLWNRLRTHRGAMSg.....tyEGGGNHRGSVFRKRVGEAIIDRDGYQ.eEYP.EWG....NGSS....ADREL..........RLEELEMEQQVSEYVRE.L.PFL.WVKVDDEPGPESERVYLERNAIALLSNYQK..TAIDARSESWLGKY...SRSEEIRRSGLWNINHV...E.E..NYDSDFLDLFEQKIEETN--si........................
A0A0X8G8D7_9FLAO/5-212               ........................veelhilfnkkrrftfpfesv--------------------------------ESYIP.KNGIYVLFEKGEYFK......DLD--RIVQIGSH----TGENQLVPRLKQHFLLE-........----NKNRSIFRKNIGRCLLKKSNNQ..YID.KWE....LDTT....SRIDKeknl..kklnLDFEKELEKEISEIIQKkI.SFC.VIELNDKR----KRLDFVKKMISTF---GK..SNELIPSENWLGNF...SPKEKIFRSGLWQVNNL...KgN..GFSDNEYKELKEL-------ie........................
A0A370HB89_9HYPH/1-199               .............................................---------------------------------MDWP.NRGVYFFMEDGETRS.....dSGSGPRIVRVGTHALTDSSCTKLWVRLRQHRGQGK........SGGGNHRGSIFRLIVGAALMARYGHD..-FP.TWG....QGNN....APADV..........RLGEITLEREVSKVIGA.M.PFL.CLAIEDEASPRSLRGYIERNSIALLSNFEK..GPLDPPSAGWLGHS...CNRERVRTSGLWNQNHV...D.E..VYDPAFLGRLEALVSNTEQ-a.........................
A0A239EMX4_9ACTN/3-230               ............................................d-RRAADTDRLYALLGDLAARLGGTRHLPTTT--SGLP.SHGVYFFFEPAETRA......DGS-PRVVRVGTHALTATSRATLRGRLAQHRGIIGg.....rfPGGGNHRGSIFRRHIGTALLASGNWE.pAVA.ASW....TAHR....AGAAA..........RAIEYSLERAVSARLVA.M.PLL.WLPVPTAA----DRGRVERNSIALLSHRT-..GGIDSPSPLWLGRH...AAAERVRTSGLWNVNHV...D.E..PYDPAYLDLFAQLVDST---ptl.......................
A0A2C9CZX8_9HYPH/1-207               ............................................m---------------------------GECHGRMEWP.ERGVYFFFEPGEFHT.....vDPAAHRVTRVGTHALTEKSRTTLWKRLSQHRGTAN........PRGGNHRGSILRLLVGEALINRDKAT..SLE.SWG....QKSS....APHQV..........RLAERPHEVAVSEYLGA.M.SLL.FLPVADNPGVESARGLIERNSIALLSGFGS..PSPDPPSCAWLGQF...SGRDRVRRSGLWNNRHV...D.E..NYDPDFLPLLIDQIDRV---sla.......................
Q2IUD9_RHOP2/141-375                 .........................................asla----DSFRQFYKIMHELYVAQGGGRLLADCTGRQGWP.DRGVYFFLENNEANAas..lfPRRMPRIVRVGTHAVSSGSKTTLWDRLSTHRGAL-........SGGGSHRSSIFRLHVGRTLLTSQPEF.gNLK.SWG....VGQV....ASKEI..........RTTESALEAEVSKTLGT.M.RVL.WLDIGDEPAVDSDRAFVEQSSIGLLSRFN-..VLTPQAPDEWLGRQ...SHDYRIFLSGLWNLNYT...F.R..RPHREFLTVLRRYVDI----tlqr......................
A0A1J1AEC5_9EURY/4-245               ............................................v-NRRQHLDRLYALLKVLENRLGGTRKLKDCTGYMDWP.DRGVYFFLEPGERRD......STDQLRVTRVGTHAVSAGSSTTLWNRLKQHYGTGSns...tnhPHGGNHRGSVYRKRVGEAIIEKHDLQ.eDYP.NWG....DRWSgidrDRAEV..........RDEEYPLERRVSAYIRE.Q.PFL.WIEIEDEPGPDSDRALIEQNAIALLSNFED..QTIDSRRNDWLGKH...SRSREIRESGLWNVNHV...E.Q..THDAHFLDVLAEAIDEM---prr.......................
A0A844W1H0_9RHOB/1-216               ............................................m----------------LEGRLGATRTLAKSAS-RDCP.QRGVYFFFEPGEQRS.....gSGDGARVVRVGTHALKPGSNTKLWTRLSQHRGALR........SGGGNHRGSIFRLLVGSALIARDGLS..-CP.TWD....TQRS...nAPSPV..........RAAEVEMERLVSRSIGA.M.PVL.WLSVDDDPGAESERGVIERGAIALLSGWGQ..AGIDPPSVNWLGHA...CTRDKVRRSGLWNNNHV...D.E..AYDPRFLDVMERRVLET---pc........................
E3PVE8_ACESD/137-355                 .................................nnqyaeednyck---------------EIHELFNNANRLYHYDITQ-IPfENGIYVMFERGEKYG......--YFDRIVRIGTH----KSDGRLKNRLKDHFQKE-........----NKDGSIFRKNIGLALLHKNKNP.yEYI.WSL....DESK....ADTRTkfl...dainSENKLSIEKEVTNYLHNnI.SFV.CFEVETKE----KRLRIEEGLISLLNNTN-..--DFYSSDSWLGKH...SPKLEIAQSGLWNTQGL...NaR..QLSNSEISDLKNMI------dgef......................
A0A1T4X4Z0_9BACT/4-233               ............................................n-SRVEHLVRLYGCLDELEKRIGGKLELSACHGRMNWP.NQGVYFFFEDGEERT.....gSGNGPRVVRVGTHAVSKGSKTTLWKRLYQHKGTEK........TGGGNHRVSIFRLNVGAALQQAGKIE..SIS.SWG....KSSS....ASREI..........VNTEFEAEKYVSNYIGK.M.PFL.FIRIEDESSKESDRAFLEKNLIGLLSEFEK..APIDPPSKTWLGNK...SPKPEIGSSGLWNSNYI...E.F..DYDPNFLNLLEHYICN----m.........................
A0A840W305_9ACTN/3-232               ............................................t-TRQRHIDEFYALLDDLARVVGGPRLLRDCTGRDAWP.SHGVYFFLEEGERLP......SGK-HRVVRVGTHALTPTSRTTLWKRLAQHRGNR-........SGGGDHRASIFRRHVGAALIGRDDSH.dGLL.EAW....LAPS....RSPAW..........TSHEAEVERRVSEYVGR.M.PFL.WLPVPTGADGNSDRGFVERNCIALLSGAS-..GTLKAPSRTWLGYH...AVSPKVRASGLWNVNHV...E.E..SYDPAVLDLIRDLVRRC---gdq.......................
A0A849L6Y2_9RHOB/3-232               ............................................n-KRLSDVERFYGLLEELSHRLGGPRRLSDCSGKLNWP.SRGVYFFMEDGETRS.....eSGSGQRIVRVGTHALTATSRTTLWTRLSQHRGTVR........NGGGNHRASIFRLLIGDALLGAGTHS..-CP.SWN....ARKH...dVSAAD..........IAAELPLEQAVSRNIAA.M.HVL.WLEVDDAPGGNSKRGIIERGAISLLSNHER..AWIDPPSTNWLGHN...STRPLVRDSGLWNQNHV...C.E..PDNPAFLDLFEELVER----v.........................
#=GC seq_cons                        ..........................................................h..l.t..tt...ltp.tthhshP.ppGlYFFFEsGEpps......ssst.RlVRVGTHAlp.sSpssLhsRLppHhGst..........tuGNHRGSlFRppVGcAllp+ssht...hs.pWs.....sps....sppph..........+ttEhtlEppVScalpp.h.sFL.alsVsDcsu.pSpRuhlEcssIALLSshp....shDssSssWLGpp...SsppcIRpSGLWNssHV...c.-..ta-staLshhpphltt....s.........................
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