GenomeNet

Database: Pfam
Entry: GP120
LinkDB: GP120
Original site: GP120 
#=GF ID   GP120
#=GF AC   PF00516.20
#=GF DE   Envelope glycoprotein GP120
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Pfam-B_44 (release 1.0)
#=GF GA   19.90 18.00;
#=GF TC   283.10 129.70;
#=GF NC   18.40 17.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Envelope_glycoprotein_GP120
#=GF RN   [1]
#=GF RM   9641677
#=GF RT   Structure of an HIV gp120 envelope glycoprotein in complex with
#=GF RT   the CD4 receptor and a neutralizing human antibody. 
#=GF RA   Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, Hendrickson
#=GF RA   WA; 
#=GF RL   Nature 1998;393:648-659.
#=GF DR   INTERPRO; IPR000777;
#=GF DR   SCOP; 1gc1; fa;
#=GF DR   HOMSTRAD; GP120;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   The entry of HIV requires interaction of viral GP120 with
#=GF CC   Swiss:P01730 and a chemokine receptor on the cell surface.
#=GF SQ   45
#=GS ENV_HV1ET/33-149       AC Q75008.1
#=GS C7TQ79_9HIV1/32-509    AC C7TQ79.1
#=GS E7CWP5_SIV/24-525      AC E7CWP5.1
#=GS E7CWP5_SIV/24-525      DR PDB; 6TYB G; 44-492;
#=GS ENV_HV192/132-504      AC O12164.1
#=GS K4IV63_9PLVG/37-524    AC K4IV63.1
#=GS ENV_HV1AN/139-513      AC Q77377.1
#=GS ENV_HV1JR/33-503       AC P20871.1
#=GS ENV_HV1JR/33-503       DR PDB; 5V6L Q; 308-325;
#=GS ENV_HV1JR/33-503       DR PDB; 4R2G A; 199-491;
#=GS ENV_HV1JR/33-503       DR PDB; 1CE4 A; 1-35;
#=GS ENV_HV1JR/33-503       DR PDB; 4R2G O; 199-491;
#=GS ENV_HV1JR/33-503       DR PDB; 5V6M P; 303-317;
#=GS ENV_HV1JR/33-503       DR PDB; 4R2G E; 199-491;
#=GS ENV_HV1JR/33-503       DR PDB; 4R2G K; 199-491;
#=GS ENV_HV1JR/33-503       DR PDB; 5V6L P; 308-323;
#=GS Q9Q6V8_9HIV1/138-495   AC Q9Q6V8.1
#=GS ENV_SIVCZ/33-150       AC P17281.1
#=GS ENV_HV190/30-145       AC O70902.1
#=GS ENV_HV1EL/33-508       AC P04581.1
#=GS ENV_SIVMB/37-527       AC Q1A261.1
#=GS ENV_HV2ST/23-505       AC P20872.2
#=GS ENV_HV2ST/23-505       DR PDB; 5CAY G; 41-503;
#=GS C7TQ97_9HIV1/143-506   AC C7TQ97.1
#=GS Q9YX49_9HIV1/131-509   AC Q9YX49.1
#=GS ENV_HV1B1/34-511       AC P03375.1
#=GS ENV_HV1H2/34-511       AC P04578.2
#=GS ENV_HV1H2/34-511       DR PDB; 3DNL A; 90-124;
#=GS ENV_HV1H2/34-511       DR PDB; 3J70 U; 34-500;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNO G; 90-124;
#=GS ENV_HV1H2/34-511       DR PDB; 3J70 D; 34-500;
#=GS ENV_HV1H2/34-511       DR PDB; 1RZJ G; 195-492;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNN F; 410-492;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNO H; 198-396;
#=GS ENV_HV1H2/34-511       DR PDB; 3TYG A; 60-185;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNO D; 90-124;
#=GS ENV_HV1H2/34-511       DR PDB; 2NY7 G; 83-492;
#=GS ENV_HV1H2/34-511       DR PDB; 4JPJ C; 57-172;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNN C; 410-492;
#=GS ENV_HV1H2/34-511       DR PDB; 4JPJ B; 57-172;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNL I; 410-492;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNN A; 90-124;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNL E; 198-396;
#=GS ENV_HV1H2/34-511       DR PDB; 6NPR R; 1-10;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNN H; 198-396;
#=GS ENV_HV1H2/34-511       DR PDB; 3J70 P; 34-500;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNL C; 410-492;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNO I; 410-492;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNN I; 410-492;
#=GS ENV_HV1H2/34-511       DR PDB; 3IDY A; 83-492;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNN E; 198-396;
#=GS ENV_HV1H2/34-511       DR PDB; 5IVX P; 1-10;
#=GS ENV_HV1H2/34-511       DR PDB; 1GC1 G; 90-492;
#=GS ENV_HV1H2/34-511       DR PDB; 1G9M G; 83-492;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNO E; 198-396;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNL H; 198-396;
#=GS ENV_HV1H2/34-511       DR PDB; 3IDX G; 83-492;
#=GS ENV_HV1H2/34-511       DR PDB; 6NPR P; 1-10;
#=GS ENV_HV1H2/34-511       DR PDB; 4JPJ D; 57-172;
#=GS ENV_HV1H2/34-511       DR PDB; 6B9K A; 1-10;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNO A; 90-124;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNO F; 410-492;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNL B; 198-396;
#=GS ENV_HV1H2/34-511       DR PDB; 3IDY G; 83-492;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNO B; 198-396;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNN G; 90-124;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNL G; 90-124;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNN D; 90-124;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNL D; 90-124;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNO C; 410-492;
#=GS ENV_HV1H2/34-511       DR PDB; 4JPJ A; 57-170;
#=GS ENV_HV1H2/34-511       DR PDB; 4JPK A; 57-169;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNL F; 410-492;
#=GS ENV_HV1H2/34-511       DR PDB; 3DNN B; 198-396;
#=GS Q87113_SIVSA/21-527    AC Q87113.1
#=GS ENV_HV1YF/25-142       AC O91086.1
#=GS Q90EX0_SIV/24-525      AC Q90EX0.1
#=GS ENV_HV1VI/140-487      AC Q9QSQ7.1
#=GS ENV_SIVEK/27-139       AC Q1A243.1
#=GS B3CKG3_SIV/20-536      AC B3CKG3.1
#=GS P89909_SIVTA/26-533    AC P89909.2
#=GS Q72502_9HIV1/34-509    AC Q72502.1
#=GS ENV_HV1MA/33-513       AC P04583.1
#=GS ENV_HV1MA/33-513       DR PDB; 2X4O C; 1-9;
#=GS ENV_SIVEK/127-481      AC Q1A243.1
#=GS ENV_HV1ET/140-500      AC Q75008.1
#=GS ENV_SIVCZ/143-500      AC P17281.1
#=GS ENV_HV1VI/33-143       AC Q9QSQ7.1
#=GS ENV_HV1YF/127-488      AC O91086.1
#=GS B7UES4_SIV/21-533      AC B7UES4.1
#=GS ENV_HV190/136-500      AC O70902.1
#=GS A0A1B4WRK4_SIV/24-543  AC A0A1B4WRK4.1
#=GS ENV_HV1A2/33-509       AC P03378.1
#=GS ENV_HV2RO/21-511       AC P04577.1
#=GS Q9Q6V8_9HIV1/30-144    AC Q9Q6V8.1
#=GS C7TQ97_9HIV1/33-147    AC C7TQ97.1
#=GS ENV_HV1MV/35-523       AC Q79670.1
#=GS Q9YX49_9HIV1/33-144    AC Q9YX49.1
#=GS ENV_HV1B9/33-508       AC Q73372.2
#=GS ENV_HV1B9/33-508       DR PDB; 4R4H A; 47-488;
#=GS ENV_HV1AN/34-142       AC Q77377.1
#=GS ENV_SIVTN/23-502       AC Q8AIH5.1
#=GS ENV_HV192/33-146       AC O12164.1
#=GS ENV_HV2BE/24-510       AC P18094.1
ENV_HV1ET/33-149                  ............LWVTVYYGVPVWKDASPTLFCAsdakaydTEVHNVWGTFACVP..TDPS...PQELGLeNVTENF.N..MW..K..ND..MVEQMHQDIISLWDQGLKPCVKLTPLCVTLNCNA.IKNNT..K.VTNNSINS------.----------------..-----..---------------.-----.----------.....---...----........-...-..-.....-..-...-..-...-.-----------------------------------------------------------------------------------..-..--........--..--...--..--------------------.--------....----..-...-..-...---..----------.---------------..........--....-..----........----.............-----.-.-------------------------------............-....---....-.-..--.---......................-------------------------...--------------------.-.-----.--...--------------------------------...---.-.------and..........
C7TQ79_9HIV1/32-509               ............LWVTVYYGVPVWRDAETTLFCAsdakayeTEIHNVWATHACVP..TDPD...PQEMALpNVTENF.N..MW..K..NN..MVEQMHTDIISLWDQGLKPCVKLTPLCVTLNCTN.VN-IT..N.I-------------.--NNTN-INNQT---V..NNQTI..GDATQDMKNCSFNMT.TILTDkKEKVQALFYK.....LDI...VPIN........GngsD..S.....N..N...S..E...YrLINCNTSTIAQACPKITFEPIPIHYCAPAGFAILKCRDKNFNGTGP-CKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEVKIRS..E..NF.......tDN.tKN...II.vQFAK--SVQINCTRPGNNTR.KSIRIGPGq..aFYAT..G...E..V...TG-..DIRQAHCNIStQDWNNTLHLVVVQLE..........KH....-..----........-YPN.............KTIVF.-.KQPSGGDLEVTMHSFNCRGEFFYCNTSSLFN............S....T-Y....L.N..IT.KGNit..................mlPCRIKQIVNMWQGVGRAIYAPPIAG...KIQCVSNITGLILTRDGGNE.D.NNTET.-FrpgGGNMKDNWRSELYKYKVVKIEPLGIAPTKAKR...--R.V.VEREKR.............
E7CWP5_SIV/24-525                 ............LYVTVFYGVPAWRNATIPLFCA.......TKNRDTWGTTQCLP..DNGD...YSEVAL.NVTESF.D..AW..N..NT..VTEQAIEDVWQLFETSIKPCVKLSPLCITMRCNK.SETDRwgL.TKSITTTASTTSTT.ASAKVDMVNETSSCIA..QDNCT..GLEQEQMISCKFNMT.GLKRD.KKKEYNETWY.....SAD...LVCEq......gN...N..T.....GneS...R..C...Y.MNHCNTSVIQESCDKHYWDAIRFRYCAPPGYALLRCNDTNYSGFMPKCSKVVVSSCTRMMETQTSTWFGFNGTRAENRTYIYW..H..GR........DN..RT...II..SLNKYYNLTMKCRRPGNKTV.LPVTIMSG....LVFH..S...Q..P...IND..RPKQAWCWFG.GKWKDAIKEVKQTIV..........KH....P..RYTG........TNNT.............DKINL.T.APG-GGDPEVTFMWTNCRGEFLYCKMNWFLN............W....VED....R.N..TA.NQKpkeqh............krnyvPCHIRQIINTWHKVGKNVYLPPREG...DLTCNSTVTSLIANIDWID-.G.NQTNI.TM...SAEVAELYRLELGDYKLVEITPIGLAPTDVKR...YTT.GgTSRNKR.............
#=GR E7CWP5_SIV/24-525      SS    ............XXXXXXXXXX-EEE-----EEE.......ESS--EETTEE-EE..----...---EE-.S--EEE.E..SS..S..-H..HHHHHHHHHHHHHHHHS--SEEEEXXXXXXXXXX.XXXXXXXX.XXXXXXXXXXXXXX.XXXXXXXXXXXXXXXX..XXXXX..XXXXXXXXXXXXXXX.XXXXX.XXXXXXXXXX.....XXX...XXXXX......XX...X..X.....XXXX...X..X...X.XXXXXX-EEE----S------EEEEE--TTEEEEEE--TT--SEEEEE--EEEESB---EE----SSEEES-S---SS-EEEE..-..TT........SS..EE...EE..E--GGG--EEEEEE-XXXXX.XXXXXXXX....XXXX..X...X..X...XX-..--SEEEEEEE.S-HHHHHHHHHHHHH..........H-....T..T--S........---G.............GGEEE.E.--S-EESHHHHSEEEEETTEEEEE--HHHHH............H....HTT....-.-..-T.TS-GGG--............--SEEEEEEESEEE-SSSSEEEE------S...-EEEEEEEEEEEEEEE-SS-.S.S-EEE.EE...---TTHHHHHHHTTEEEEEE-XXXXXXXXXXX...XXX.XXXXXXXX.............
ENV_HV192/132-504                 .....nrtidyn----------------------.......--------------..----...------.------.-..--..-..--..----------------------------------.-----..-.--------------.----------------..--NRT..DNMGGEIKNCSFNMTtEVRDK.REKVHALFYR.....LDI...VPLK........N...E..S.....S..N...T..Sg.dYrLINCNTSAITQACPKVSFDPIPIHYCAPAGYAILKCNNKTFNGTGP-CNNVSTIQCTHGTKPVVSTQLLLNGSLAEEEIIIRS..K..NL.......tDN.vKT...II.vHLNE--SVEINCTRPNNNTR.KSIRIGPGq..aFYAT..G...E..I...IGD..-IRQAHCNISrTAWNKTLQEVGKKLA..........EH....-..----........-FPN.............KAIKF.A.K-HSGGDLEITTHSFNCRGEFFYCNTSSLFNsty......tpnS....TEN....I.T..GT.ENSii..................tiPCRIKQIINMWQGVGRAMYAPPIEG...ILTCRSNITGLLLTRDGGTG.M.HDTEI.-FrpeGGDMRDNWRSELYKYKVVEIKPLGIAPTKAKR...--R.V.VEREKR.............
K4IV63_9PLVG/37-524               ............LWVTVYYGVPVWKEAKTTLFCAsdakaydTEVHNVWATHACVP..TDPN...PQEMVLgNVTENF.N..MW..K..NE..MVDQMQEDVISLWDQSLKPCVKLTPLCVTLECKN.VSKHN..A.S-----------VT.NSTLSGTYNESG----..-----..----QEIKNCTFNVTtELRDK.KKKEYALFYR.....LDI...VPLDeen..ssnN...S..T.....S..N...N..SsgnYrLINCNTSAITQACPKVNFDPIPIHYCTPAGYAILKCNNKTFNGTGP-CNNVSTVQCTHGIKPVVSTQLLLNGSLAEEEIIIRS..E..NL.......tDN.vKT...II.vHLNK--PVEIECIRPNNNTR.KSIRIGPGq..tFYAT..G...E..I...IGD..-IRQAYCIINaSQWNETLYNVSKKLA..........ER....-..----........-FNN.............RTINF.-.TSSSGGDLEITTHSFNCRGEFFYCNTSRLFN............S....TYM....S.N..GT.YTYtinsn...........isnitiPCRIKQIVNMWQEVGRAMYAPPIAG...NITCKSNITGLLLVRDGGSN.E.TQPEI.-FrpgGGDMRDNWRSELYKYKVVEIKPLGLAPTTAKR...--R.V.VEREKR.............
ENV_HV1AN/139-513                 ........nenl----------------------.......--------------..----...------.------.-..--..-..--..----------------------------------.-----..-.--------------.----------------..-----..------MKKCEFNVTtVIKDK.KEKKQALFYVsdlmeLNE...TSST........N...K..T.....N..S...K..M...YtLTNCNSTTITQACPKVSFEPIPIHYCAPAGYAIFKCNSTEFNGTGT-CRNITVVTCTHGIRPTVSTQLILNGTLSKGKIRMMA..K..DIl......eGG..KN...II.vTLNS--TLNMTCERPQIDIQeMRIGPMAWy..sMGIG..G...T..A...GNS..-SRAAYCKYNaTDWGKILKQTAERYL..........EL....-..----........VNNT.............GSINM.TfNHSSGGDLEVTHLHFNCHGEFFYCNTAKMFN............Y....TFS....C.N..GT.TCSvsnvsq..........gnngtlPCKLRQVVRSWIRGQSGLYAPPIKG...NLTCMSNITGMILQMDNTWN.S.SNNNV.TFrpiGGDMKDIWRTELFNYKVVRVKPFSVAPTRIARp.vIST.R.THREKR.............
ENV_HV1JR/33-503                  ............LWVTVYYGVPVWKETTTTLFCAsdakaydTEVHNVWATHACVP..TDPN...PQEVVLeNVTEDF.N..MW..K..NN..MVEQMQEDVINLWDQSLKPCVKLTPLCVTLNCKD.VNA-T..N.T-------------.-TSSSEGMMERG----..-----..-----EIKNCSFNITkSIRDK.VQKEYALFYK.....LDV...VPID........N...K..N.....-..N...T..K...YrLISCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGKGQ-CKNVSTVQCTHGIRPVVSTQLLLNGSLAEEKVVIRS..D..NF.......tDN.aKT...II.vQLNE--SVKINCTRPSNNTR.KSIHIGPGr..aFYTT..G...E..I...IGD..-IRQAHCNISrAQWNNTLKQIVEKLR..........EQ....-..----........-FNN.............KTIVF.-.THSSGGDPEIVMHSFNCGGEFFYCNSTQLFNs..........tWn..dTEK....S.S..GT.EGNdt.................iilPCRIKQIINMWQEVGKAMYAPPIKG...QIRCSSNITGLLLTRDGGKN.E.SEIEI.-FrpgGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKR...--R.V.VQREKR.............
#=GR ENV_HV1JR/33-503       SS    ............XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..XXXX...XXXXXXXXXXXXX.X..XX..X..XX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXX-X..X.X-------------.-XXXXXXXXXXX----..-----..-----XXXXXXXXXXXXXXXX.XXXXXXXXXX.....XXX...XXXX........X...X..X.....-..X...X..X...XXXXXXXXCEEEXXXXXXXXXXXXBXXBXXTTEEEEEEXXSSXXSBSX-XSSEEEESBXXXBXXXXBSSEEESXXXXSSSXEEEX..S..XS.......SXS.SSX...EE.EEEEE--EEEEEEEESSGGXX.SSXS-STTH..HHHHH..C...H..H...HSH..-HHHTEEEEEHHHHHHHHHHHHHHHH..........HH....-..----........-TTT.............XEEEE.-.XXXSSBSHHHHTEEEEETTEEEEEXXTTTTXE..........EES..SSSS....E.E..ST.XXXSE.................EEEEEEEESEEEXSSSSSEEEXXXXSSS...XEEEEEEEEEEEEEEXXSSS.X.TSEEE.-EEEXBXXHHHHHHHHHTTEEEEEXXXXXXXXXXXXX...--X.X.XXXXXX.............
Q9Q6V8_9HIV1/138-495              ........ntss----------------------.......--------------..----...------.------.-..--..-..--..----------------------------------.-----..-.--------------.----------------..-----..-IKMMEMKNCSFNITtDLRDK.VKKEYALFYK.....LDV...VQID........N...D..S.....-..-...-..-...YrLISCNTSVVTQACPKISFEPIPIHYCAPAGFAILKCNDKKFNGTGP-CTNVSTVQCTHGIKPVVSTQLLLNGSLAEEEVVIRS..V..NF.......tDN.tKT...II.vQLKE--PVEINCTRPNNNTR.KGIHIGPGr..aFYAT..G...D..I...TGD..-IRQAHCNISiTKWNNTLKQIVIKLR..........KQ....-..----........FG-N.............KTIVF.-.NQSSGGDPEIVMHSFNCGGEFFYCNTTKLFNs..........tWn..gTEE....L.N..NT.EGDiv..................tlPCRIKQIINMWQEVGKARYAPPIAG...QIRCSSNITGLLLTRDGGNQ.S.NVTEI.-FrtgGGDMRDNWRSELYKYKVVKIEPLGVAPTRAKR...--R.V.VQREKR.............
ENV_SIVCZ/33-150                  ............LWVTVYYGVPVWHDADPVLFCAsdakahsTEAHNIWATQACVP..TDPS...PQEVFLpNVIESF.N..MW..K..NN..MVDQMHEDIISLWDQSLKPCVKLTPLCVTLQCSK.ANFSQ..-.--------------.----------------..-----..---------------.-----.----------.....---...----........-...-..-.....-..-...-..-...-.-----------------------------------------------------------------------------------..-..--........--..--...--..--------------------.--------....----..-...-..-...---..----------.---------------..........--....-..----........----.............-----.-.-------------------------------............-....---....-.-..--.---......................-------------------------...--------------------.-.-----.--...--------------------------------...---.-.------aknltnqtssppl
ENV_HV190/30-145                  ............LWVTVYYGVPVWKEAKTTLFCAsdakayeTEKHNVWATHACVP..TDPN...PQEMVMeNVTESF.N..MW..E..NN..MVEQMHTDIISLWDQSLKPCVKLTPLCVTLNCTN.VRNNT..S.NS------------.----------------..-----..---------------.-----.----------.....---...----........-...-..-.....-..-...-..-...-.-----------------------------------------------------------------------------------..-..--........--..--...--..--------------------.--------....----..-...-..-...---..----------.---------------..........--....-..----........----.............-----.-.-------------------------------............-....---....-.-..--.---......................-------------------------...--------------------.-.-----.--...--------------------------------...---.-.------tssmeagg.....
ENV_HV1EL/33-508                  ............LWVTVYYGVPVWKEATTTLFCAsdaksyeTEAHNIWATHACVP..TDPN...PQEIALeNVTENF.N..MW..K..NN..MVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCSDeLRNNG..T.MGNN----------.-----VTTEEKG----..-----..------MKNCSFNVTtVLKDK.KQQVYALFYR.....LDI...VPID........N...DssT.....N..S...T..N...YrLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCRDKKFNGTGP-CTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVIIRS..E..NL.......tNN.aKN...II.aHLNE--SVKITCARPYQNTR.QRTPIGLG....QSLY..T...T..R...SRS..IIGQAHCNISrAQWSKTLQQVARKLG..........TL....-..----........-LNK.............TIIKF.-.KPSSGGDPEITTHSFNCGGEFFYCNTSGLFNstw.....nisaWn.niTES....N.N..ST.NTNi...................tlQCRIKQIIKMVA-GRKAIYAPPIER...NILCSSNITGLLLTRDGGIN.N.STNE-.TFrpgGGDMRDNWRSELYKYKVVQIEPLGVAPTRAKR...--R.V.VEREKR.............
ENV_SIVMB/37-527                  ............MWVTVYYGVPVWREADTTLFCAsdakaqnPEVHNVWASQACVS..TNPN...PEEIELtNVTEYF.N..AW..E..NN..MVEQMHEDIVNLWDQSVKPCVKLIPLCVTLNCSL.FKCIK..E.NGNTTNCTVQISTG.NDSTANNI--------..-----..TVGTIDMYNCSFNATtELRDR.KKQVYSLFYR.....QDL...EPLE........G...N..KppegdK..N...A..L...YrLYNCNTTAMTQACSKVSLEPIPIHYCAPAGFALLKCNDKNFTGIGQ-CKNVSTVHCTHGIRPVVSTQFLLNGTLEEKVTVLDR..N..VS.......nDM..DT...II.vKLNE--TVRLNCTRTGNNTI.KGIPIGPS....QIFY..GietV..I...GD-..-TRQAFCQLNkTVWTNTFKKVRHALN..........ET....-..-YKG........YLGN.............ETITF.-.GPSTGGDLEVTNLHLICGGEFFYCNTSILFNts........iiF....NET....K.D..DN.ITI......................PCRIRQIVRLWQRVGRGIFLPPIRG...TINCISNITGILFAQQKTDR.M.NKSAM.-FtpvGGEMRNNWRSELYKYKVVRIEPLGVAPTKAKR...--R.T.VHREKR.............
ENV_HV2ST/23-505                  ............QYVTVFYGVPVWRNASIPLFCA.......TKNRDTWGTIQCLP..DNDD...YQEIAL.NVTEAF.D..AW..N..NT..VTEQAVEDVWSLFETSIKPCVKLTPLCVAMRCNS.TTAKN..T.TSTP-----T---T.TTTANTTIGENSSCIR..TDNCT..GLGEEEMVDCQFNMT.GLERD.KKKLYNETWY.....SKD...VVCE.......sN...D..T.....KkeK...T..C...Y.MNHCNTSVITESCDKHYWDTMRFRYCAPPGFALLRCNDTNYSGFEPNCSKVVAATCTRMMETQTSTWFGFNGTRAENRTYIYW..H..GR........DN..RT...II..SLNKFYNLTVHCKRPGNKTV.VPITLMSG....LVFH..S...Q..P...INR..RPRQAWCWFK.GEWKEAMKEVKLTLA..........KH....P..RYKG........TNDT.............EKIRF.I.APGERSDPEVAYMWTNCRGEFLYCNMTWFLN............W....VEN....RtN..QT.QHNy....................vPCHIKQIINTWHKVGKNVYLPPREG...QLTCNSTVTSIIANIDGGEN.-.-QTNI.TF...SAEVAELYRLELGDYKLIEVTPIGFAPTPVKR...YSS.A.PVRNKR.............
#=GR ENV_HV2ST/23-505       SS    ............XXXXXXXXXXXXXXXXX--EEE.......--------------..--S-...--EEEE.S--EEE.E..SS..S..-H..HHHHHHHHHHHHHHHHB--SEEE-XXXXXXXXXX.XXXXX..X.XXXX-----X---X.XXXXXXXXXXXXXXXX..XXXXX..XXXXXXXXXXXXXXX.XXXXX.XXXXXXXXXX.....XXX...XXXX.......XX...X..X.....XXXX...X..X...X.XXXXSS-EEE----S-B----EEEEE--TTEEEEEE--TT--SEEEEE-SEEEESB---EE----SSEEES-S--BSS-EEEE..-..SS........S-..EE...EE..E-BTTS--EEEEEE---XXX.XXXXXXXX....XXXX..X...X..X...XX-..-TTEEEEE--.S-HHHHHHHHHHHHH..........TS....S..---S........---S.............SSEEE.E.---TTS-HHHHTEEEEETTEEEEE--HHHHH............T....TT-....---..--.--SE....................EEEEEESEEE-SSSS-EEE-----SS...-EEEEEEEEEEEEEEE----.-.--EEE.EE...----HHHHHHHHTTEEEEE--XXXXXXXXXXX...XXX.X.XXXXXX.............
C7TQ97_9HIV1/143-506              ........tdin----------------------.......--------------..----...------.------.-..--..-..--..----------------------------------.-----..-.--------------.----------------..-----..----REMRNCSFNMTtVLRDK.QEKVHALFYR.....LDI...VLMN.......gN...D..Sk...nS..S...G..E...YrLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCRDKDFNGTGL-CTNVSTVQCTHGIKPVVSTQLLLNGSLAEGGVKVRS..E..NF.......tNN.aKN...II.vQFDK--AVVINCSRPNNNTR.KSIHLGPGq..sFYAT..G...D..I...IGD..-IRQAACNISrKDWDKALSKVAKQLS..........DH....-..----........-FPN.............KSIAF.-.NQSSGGDLEITMHSFNCRGEFFYCNTSGLFNrtw.....kdgnW....TTQ....E.N..GT.NENi...................tlPCRIKQIVRMWQEVGQAMYAPPVAG...MIQCISNITGLILTRDGGKD.K.NDTEI.-FrpgGGNMKDNWRSELYKYKVVQIEPLGLAPTKARR...--R.V.VEREKR.............
Q9YX49_9HIV1/131-509              .......inatt----------------------.......--------------..----...------.------.-..--..-..--..----------------------------------.-----..-.--------------.---------------T..NSTNG..TVIKEGIKNCSFDITtEIRDK.KKKEYALFYR.....IDI...VPINarvpingsN...R..N....nS..T...E..E...YmLINCNASTIKQACPKVSFEPIPIHYCAPAGFAILKCNEKNFTGLGP-CTNVSSVRCTHGIKPVVSTQLLLNGSLATEEVVIRS..K..NI.......tDN.tKN...II.vQLAK--AVKINCTRPGNNTR.KSVHIGPG....LTWYatG...E..I...IGD..-IRQAHCNISgNDWNDTLKVISEELK..........RL....-..----........-FPN.............KTIKF.-.APPVGGDLEITTHSFNCKGEFFYCNTTPLFNsthmq.ngtnitS....TDS....T.N..ST.ITL......................QCRLKQFVRMWQEVGQAMYASPIAG...SINCSSDITGIILTRDGGTN.N.TEI--.-FrpgGGDMRDNWRSELYKYKVVKIEPIGVAPNKARR...--R.V.VQREK-.............
ENV_HV1B1/34-511                  ............LWVTVYYGVPVWKEATTTLFCAsdakaydTEVHNVWATHACVP..TDPN...PQEVVLvNVTENF.N..MW..K..ND..MVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTD.LKNDT..N.T-------------.NSSSGRMIMEKG----..-----..-----EIKNCSFNIStSIRGK.VQKEYAFFYK.....LDI...IPID........N...D..T.....-..-...T..S...YtLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGP-CTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRS..A..NF.......tDN.aKT...II.vQLNQ--SVEINCTRPNNNTR.KSIRIQRGpgraFVTI..G...K..I...GNM..--RQAHCNISrAKWNNTLKQIDSKLR..........EQ....-..----........FGNN.............KTIIF.-.KQSSGGDPEIVTHSFNCGGEFFYCNSTQLFNstw.....fnstW...sTKG....S.N..NT.EGSdt.................itlPCRIKQIINMWQEVGKAMYAPPISG...QIRCSSNITGLLLTRDGGNS.N.NESEI.-FrpgGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKR...--R.V.VQREKR.............
ENV_HV1H2/34-511                  ............LWVTVYYGVPVWKEATTTLFCAsdakaydTEVHNVWATHACVP..TDPN...PQEVVLvNVTENF.N..MW..K..ND..MVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTD.LKNDT..N.T-------------.NSSSGRMIMEKG----..-----..-----EIKNCSFNIStSIRGK.VQKEYAFFYK.....LDI...IPID........N...D..T.....-..-...T..S...YkLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGP-CTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRS..V..NF.......tDN.aKT...II.vQLNT--SVEINCTRPNNNTR.KRIRIQRGpgraFVTI..G...K..I...GNM..--RQAHCNISrAKWNNTLKQIASKLR..........EQ....-..----........FGNN.............KTIIF.-.KQSSGGDPEIVTHSFNCGGEFFYCNSTQLFNstw.....fnstW...sTEG....S.N..NT.EGSdt.................itlPCRIKQIINMWQKVGKAMYAPPISG...QIRCSSNITGLLLTRDGGNS.N.NESEI.-FrpgGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKR...--R.V.VQREKR.............
#=GR ENV_HV1H2/34-511       SS    ............SSXXXXEEEXXEEEXXXXXEEEXXXXTTXXXHHHHHHHHSXBX..XXSS...XXXEEESSEEEEE.E..TS..S..TS..SHHHHHHHHHHHHHHHSXXSEEEEEBSSSEEEEE.XTTXX..E.E-------------.EEEETTTTEEEE----..-----..-----EEEXSSSXXXSSEEEE.EEEEEXTTSX.....EEE...EEEX........X...S..S.....-..-...X..X...XTTXSXBEEEEEEE--SEEEEE--BEEB--SSEEEEEE--TT--SSEE-ESSEEEESB---BSSSEBSSEEESS---SSS-EEEE..S..-S.......SST.TS-...EE.EEEEE--EEEEEEEXXBSXSS.SXBXXTTTTTBTTBXX..X...X..X...SXT..--TEEEEEEEHHHHHHHHHHHHHHHH..........HT....-..----........STST.............SEEEE.-.-----CSHHHHTEEEEETTEEEEEETTTTS-EEE.....SSHHH...HHHH....H.H..HH.HHXSE.................EEEEEEEESEEEGSSSSEEEEEEXXTBS...TBEEEEEEEEEEEEEESSTT.T.SSEEE.-EEESXSSTHHHHHHHHTTEEEEEEXSXEEEXXXXXX...--X.X.XXXXXX.............
Q87113_SIVSA/21-527               ............QYVTVFYGIPVWKNSSVQAFCK.......TPNTNLWASTNCIP..DDEPegtIAEVPIpNITEKF.D..AW..K..NRnpLVGQAESNIHLLFESTLKPCVKLSPMCIKMNCYR.LEGGA..A.T--TTSPSTSTARP.EVVSVG--FNDS-VIE..QE---..-MEKEQAMNCSFAMA.GYRRD.VKKNYSTVWD.....DQE...VVCEegr..eksN...A..T....hT..V...G..C...Y.MIHCNTSVIKEACDKTYWDTFRLRYCAPAGYALLRCADTDYSGHKA-CRNVTVSACTRLINTTVSTGIGINGSYVANRTEI-W..QknGN........SN.dSV...II..RLNRYFNLTIRCRRPGNKTV.LPVTIMAG....LVFH..S...Q..K...YNT..RLKQAWCWFG.GNWRGAWKEVKETIV..........RL....PpkKYSG........TNDT.............NKIFL.-.-QRQWGDPESEFFFFNCQGEFFYCKMDWFLNylnn....ksvdP....--D....H.N..NC.AKNntkpc...........wqrtyvPCHIRQVVNDWYTLSKKTYAPPREG...HLECNSTATALYVELNY-NS.K.NRTNV.TL...SPQIESIWANELGDYKLVEIKPIGFAPTKVRR...YT-.G.PERQKR.............
ENV_HV1YF/25-142                  ...........h-WVTVYYGVPVWREAETTLFCAsdakahsTEAHNIWATQACVP..TDPN...PQEVLLpNVTEKF.N..MW..E..NK..MADQMQEDIISLWEQSLKPCVKLTPLCVTMLCND.SYGEE..R.N-------------.----------------..-----..---------------.-----.----------.....---...----........-...-..-.....-..-...-..-...-.-----------------------------------------------------------------------------------..-..--........--..--...--..--------------------.--------....----..-...-..-...---..----------.---------------..........--....-..----........----.............-----.-.-------------------------------............-....---....-.-..--.---......................-------------------------...--------------------.-.-----.--...--------------------------------...---.-.------ntnmttrepdi..
Q90EX0_SIV/24-525                 ............LYVTVFYGVPVWRNATIPLFCA.......TKNRDTWGTTQCLP..DNGD...YSEMAL.NVTESF.D..AW..N..NT..VTEQAIEDVWQLFETSIKPCVKLSPLCITMRCNK.SETDRwgL.TKSITTTASTTSTT.ASARVDMVNETSSCIA..QDNCA..GLEQEQMISCKFNMT.GLNRD.KKKEYNETWY.....SAD...LVCEq......gN...N..T.....GneS...R..C...Y.MNHCNTSVIKESCDKHYWDAIRFRYCAPPGYALLRCNDTNYSGFMPKCSKVVVSSCTRMMETQTSTWFGFNGTRAENRTYIYW..H..GR........DN..RT...II..SLNKYYNLTIKCRRPGNKTV.LPVTIMSG....LVFH..S...Q..R...IND..RPRQAWCWFG.GKWKDAIKEVKQTIV..........KH....P..RYTG........TNNT.............DKINL.T.A-PRGGDPEVTFMWTNCRGEFLYCKMNWFLN............W....VED....R.N..TA.NQKpkeqh............krnyvPCHIRQIINTWHKVGKNVYLPPREG...DLTCNSTVTSLIANIDWID-.G.NQTNI.TM...SAEVAELYRLELGDYKLVEITPIGLAPTDVKR...YTT.GgTSRNKR.............
ENV_HV1VI/140-487                 ........kpga----------------------.......--------------..----...------.------.-..--..-..--..----------------------------------.-----..-.--------------.----------------..-----..------MQNCSFNMTtEVRDK.KLKLSALFYR.....LDI...VPIG........N...N..N.....S..-...S..E...YrLINCNTSTITQACPKVSWDPIPIHYCAPAGYAILKCNDKRFNGTGP-CKNVSTVQCTHGIKPVVSTQLLLNGSLAEEGIVIRS..Q..NI.......sNN.aKT...II.vHLNE--SVQINCTRPNNNTR.KGIHLGPGq..tFYAT..G...A..I...IGD..-IRKAHCNISgTQWNNTLEYVKAELK..........SH....-..----........FPNN.............TAIKF.-.NQSSGGDLEITMHSFNCRGEFFYCDTSGLFN............D....TGS....N.N..GT.ITL......................PCRIKQIVNMWQGVGRAMYTSPIAG...NITCNSNITGLLLTRDGGNE.S.NIE--.TFrpeGGNMKDNWRSELYKYKVVEIEPLGVAPTKAKR...--Q.V.VQREKR.............
ENV_SIVEK/27-139                  ............LWVTVYYGVPVWRDAETVLFCAsdakahsTEAHNIWATQACVP..TDPN...PQEVLIpNVTERF.D..MW..K..NN..MVDQMQEDIISLWEQSLKPCVKLTPLCVTLSCSS.WRSVN..N.SV------------.----------------..-----..---------------.-----.----------.....---...----........-...-..-.....-..-...-..-...-.-----------------------------------------------------------------------------------..-..--........--..--...--..--------------------.--------....----..-...-..-...---..----------.---------------..........--....-..----........----.............-----.-.-------------------------------............-....---....-.-..--.---......................-------------------------...--------------------.-.-----.--...--------------------------------...---.-.------nqtnh........
B3CKG3_SIV/20-536                 ............QYITVYYGVPQWEEAKDFMLCA.......TENRSLWVTTHCLP..HIEE...ITEQYMeGIKENF.TkkVE..E..NE..VVQQAWTGVTSMIDTLLKPCVKINPYCVKMSCTL.GDEKS..NyTEDIELTTVKTTTP.VTPPQNTTPSM--DVE..NNSTS..LNLTDTNHVCRFNVT.GLCRD.CKQEIVESFR.....GDD...VRCT........Q...H..G.....N..Gt.qT..C...Y.INHCNESVIHQDCQKAWHDEQYIRMCAPPGYVLLRCNEKL-NSSKL-CENVSAVTCTDLMTATISSFFGFNGTKYDKGELIEV..I..GNinh..kpkDG.tGA...FV.yKVPAKYNVAIECHRKGNRSL.VSVSSASG....LIYY..A...G..L...EPY.kNIRKALCKFT.GQWGHMLYGLGKELQaynsswvnytEE....C..NKKGnssafatcIKQF.............QIRNF.T.KQGADRATENL--MMICGGEMFFCNITKIAD............W....WNN....K.T..EK.RWYp...................waPCTIRSIVDDWASIGKKIYLPPVSGfnnHIRCTQRVSEVLFNWENGQV.E.FQ---.-A...PSHMQNSFVAVGQKYKLVKLKLIGVAPTDGKR...VTPpD.HHREK-r............
P89909_SIVTA/26-533               ............QYITVFYGIPVWKNSSVQAFCM.......TPNTNLWATTNCIP..DDHD...YTEVQL.NVSEKF.E..AW..KdrNP..LVAQAESNIHLLFESTLKPCVKLTPMCIKMNCTK.LTSTA..P.TSSTPTSSSTTDPC.PNTD-----ESS-CNA..TLVTN..SMDYENSSICSFAMA.GYRRD.VKKKYNSTWY.....DQE...LVCEk......eN...N..T.....T..G...TrgC...Y.MIHCNDSVIKEACEKTYWDTLRLRYCAPAGFAILKCKDTNYTGFGV-CRNVSVVSCTGLMNTTVSSAFGINGSQAENRTEI-WqkH..GV........SN.nSV...II..KLNKHYKLKIVCRRPGNKTV.LPVTIMAG....LVFH..S...Q..Q...YNT..KLRQAWCHFQ.GDWKGAWREVRKTIV..........EL....PkeKYRG........TNNT.............RQIWL.S.RQ--WGDPEAANIWLNCQGEFFYCTPDWFVN............W....LNN....E.S..NS.GRNvdvegnncttgkdkrcykrtyvPCHIRSIVNDWYTLSKKTYAPPREG...HLECTSTVTSMMVSLDY-NS.K.ERTNV.TL...TANLENIWAYELGRYKLIEIEPIGFAPTEIRR...YV-.G.PTREKR.............
Q72502_9HIV1/34-509               ............LWVTVYYGVPVWKEATTTLFCAsdakaydTEVHNVWATHACVP..TDPN...PQEVVLvNVTENF.N..MW..K..DD..MVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTD.LKNDT..N.T-------------.NSSSGRMIMEKG----..-----..-----EIKNCSFNIStSIRDK.VQKEYAFFYK.....LDI...VPID........N...T..S.....-..-...-..-...YrLISCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGP-CTNVSTVQCTHGIRPVVSTQLLLNGSLAEEDVVIRS..A..NF.......tDN.aKT...II.vQLNT--SVEINCTRPNNNTR.KSIRIQRGpgraFVTI..G...K..I...GNM..--RQAHCNISrAKWNATLKQIASKLR..........EQ....-..----........FGNN.............KTIIF.-.KQSSGGDPEIVTHSFNCGGEFFYCNSTQLFNstw.....fnstW...sTEG....S.N..NT.EGSdt.................itlPCRIKQFINMWQEVGKAMYAPPISG...QIRCSSNITGLLLTRDGGNN.N.NGSEI.-FrpgGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKR...--R.V.VQREKR.............
ENV_HV1MA/33-513                  ............LWVTVYYGVPVWKEATTTLFCAsdaksyeTEVHNIWATHACVP..TDPN...PQEIELeNVTEGF.N..MW..K..NN..MVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTN.VNGTA..V.N-------GTNAGS.NRTNAELKMEIG----..-----..-----EVKNCSFNIT.PVGSD.KRQEYATFYN.....LDL...VQID........D...S..D.....-..N...S..S...YrLINCNTSVITQACPKVTFDPIPIHYCAPAGFAILKCNDKKFNGTEI-CKNVSTVQCTHGIKPVVSTQLLLNGSLAEEEIMIRS..E..NL.......tDN.tKN...II.vQLNE--TVTINCTRPGNNTR.RGIHFGPGq..aLYTT..G...I..V...GDI..--RRAYCTINeTEWDKTLQQVAVKLG..........SL....-..----........-LNK.............TKIIF.-.NSSSGGDPEITTHSFNCRGEFFYCNTSKLFNs..........tW....QNNgarlS.N..ST.ESTgs.................itlPCRIKQIINMWQKTGKAMYAPPIAG...VINCLSNITGLILTRDGGNS.S.DNSDNeTLrpgGGDMRDNWISELYKYKVVRIEPLGVAPTKAKR...--R.V.VEREKR.............
#=GR ENV_HV1MA/33-513       SS    ............XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..XXXX...XXXXXXXXXXXXX.X..XX..X..XX..XXXXXXXXXXXXXXXXXXXXX---SS----XXXX.XXXXX..X.X-------XXXXXX.XXXXXXXXXXXX----..-----..-----XXXXXXXXXX.XXXXX.XXXXXXXXXX.....XXX...XXXX........X...X..X.....-..X...X..X...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..X..XX.......XXX.XXX...XX.XXXXX--XXXXXXXXXXXXXX.XXXXXXXXX..XXXXX..X...X..X...XXX..--XXXXXXXXXXXXXXXXXXXXXXXX..........XX....-..----........-XXX.............XXXXX.-.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..........XX....XXXXXXXX.X..XX.XXXXX.................XXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXX.X.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...--X.X.XXXXXX.............
ENV_SIVEK/127-481                 ........wrsv----------------------.......--------------..----...------.------.-..--..-..--..----------------------------------.-----..-.--------------.----------------..NNSVN..QTNHVQMQNCSFNVTtELRDK.KKQVYSLFYM.....GDI...IPLD.......tN...N..S.....S..Gn.nS..Q...YrLINCNTTAVTQACPKISFEPIPIYYCAPPGFAIIKCNDQDFNGTGE-CNNVSTVQCTHGIKPVISTQLILNGSLATSNIVI--..-..-R........NNskDT...LL.vQLNE--SIPINCTRPGNKTR.GQVQIGPG....MTFYniE...N..I...IGD..-TRQAYCEVN.RTWEQIWNTTKQ---..........-I....-..---I........INNR.............KNITF.-.IPNPGGDLEVTNLMINCGGEFFYCNTSQLFT............-....-NQ....N.G..NT.TGNi...................tlQCRIRQIVNLWTRVGKGIYAPPIKG...PINCLSNITGIILDYT--KS.G.TEKYT.IYp.tGGDMTNLWRQELYKYKVVSIEPIGVAPGKAKR...--H.T.VTRQKR.............
ENV_HV1ET/140-500                 .......tnnsi----------------------.......--------------..----...------.------.-..--..-..--..----------------------------------.-----..-.--------------.----------------..-----..NSANDEMKNCSFNITtELRDK.KRKAYALFYK.....LDI...VPLN........N...G..S.....-..-...T..D...YrLINCNTSTITQACPKVSLDPIPIHYCAPAGYAILKCRDKTFTGTGP-CHNVSTVQCTHGIKPVVSTQLLLNGSIAEGETIIRF..E..NL.......tNN.aKI...II.vQLNE--SVEITCTRPSNNTR.ESIRIGPGq..tFYAT..G...D..I...IGD..-IRQAHCNISeEKWNKTLQKVKEKLQ..........KH....-..----........-FPN.............KTIEF.-.KPSSGGDLEITTHSFNCGGEFFYCNTSNLFNstk......lelF....NSS....-.-..-T.NLNi...................tlQCRIKQIINMWQGVGRAMYAPPIEG...IIMCRSNITGLLLTRDGAKE.P.HSTKE.IFrpeGGDMRDNWRSELYKYKVVEIKPLGVAPTKPKR...--R.V.VEREKR.............
ENV_SIVCZ/143-500                 ....nqtssppl----------------------.......--------------..----...------.------.-..--..-..--..----------------------------------.-----..-.--------------.----------------..-----..-----EMKNCSFNVTtELRDK.KKQVYSLFYV.....EDV...VNLG........N...E..N.....-..-...N..T...YrIINCNTTAITQACPKTSFEPIPIHYCAPAGFAILKCNDKDFSGKGK-CTNVSTVHCTHGIKPVVTTQLLINGSLAEGNITVRV..E..NK........SK..NTdvwIV..QLVE--AVSLNCHRPGNNTR.GEVQIGPG....MTFY..N...I..-...ENVvgDTRSAYCKINgTTWNRTVEEVKKALA..........TS....-..---S........NRTA.............ANITL.-.NRASGGDPEVTHHMFNCGGEFFYCNTSQIFT............-....---....D.N..IT.NGIi...................ilPCRIRQIVSSWMRVGRGIYAPPIRG...NITCNSNITGLLLTSDTPVT.N.NSGNL.TFrptGGNMKDIWRSELYKYKVVRIEPLSVAPTKARR...--H.T.VARQK-drqkr........
ENV_HV1VI/33-143                  ............LWVTVYYGVPVWKEATTTLFCAsdakayeREAHNVWATHACVP..TDPN...PQEVFLkNVTENF.D..MW..K..NN..MVEQMHTDIISLWDQSLKPCVKLTPLCVTLNCTN.ATNNS..Q.--------------.----------------..-----..---------------.-----.----------.....---...----........-...-..-.....-..-...-..-...-.-----------------------------------------------------------------------------------..-..--........--..--...--..--------------------.--------....----..-...-..-...---..----------.---------------..........--....-..----........----.............-----.-.-------------------------------............-....---....-.-..--.---......................-------------------------...--------------------.-.-----.--...--------------------------------...---.-.------ekpga........
ENV_HV1YF/127-488                 geernntnmttr----------------------.......--------------..----...------.------.-..--..-..--..----------------------------------.-----..-.--------------.----------------..---EP..DIGYKQMKNCSFNATtELTDK.KKQVYSLFYV.....EDV...VPIN........A...Y..N.....-..K...T..-...YrLINCNTTAVTQACPKTSFEPIPIHYCAPPGFAIMKCNEGNFSGNGS-CTNVSTVQCTHGIKPVISTQLILNGSLNTDGIVIRN..D..S-........HS..NL...LV..QWNE--TVPINCTRPGNNTG.GQVQIGPAm..tFYNI..E...K..I...VGD..-IRQAYCNVSkELWEPMWNRTREEIK..........KI....-..----........LGK-.............NNITFrA.RERNEGDLEVTHLMFNCRGEFFYCNTSKLFN............E....-EL....L.N..ET.GEPi...................tlPCRIRQIVNLWTRVGKGIYAPPIRG...VLNCTSNITGLVLEYSGGPD.T.KETIV.-Yp.sGGNMVNLWRQELYKYKVVSIEPIGVAPGKAKR...--R.T.VSREKR.............
B7UES4_SIV/21-533                 ............QYVTVFYGTPKWRDSNDTLMCV.......TANKSLWVTTACLPsfDEDE...IEQPIP.GVEEVFyN..VS..D..NE..VVRQAWFGIASLLDAVLKPCVKLTPFCVKMQCED.PSANF..T.EPITPISTAAPTTV.TSSTGGQTTTIGLGVD..NSTVK..-PETEKLKQCRYNIT.GLCRD.CKIEMNQTFD.....LED...VACT........N...N..T.....-..-...-..C...Y.MSHCNTSVITQDCQYAVSDQQMVKLCAPPGRVLIKCNNRTE---NP-CRNISAVTCTPPLSATVSSFFGFNGTRHKASRLIPI..T..GDlnhkpregTG..VY...VM..AIADKYKLEIECIRKGNRSI.VSVNSASG....LVYY..A...G..LepyGNI..--DKGLCRFK.GQWGWMLYALGKGLE..........KEnntwA..NYTG........VNITgigrnsttfakaiKRFKF.DeKLKRGGDDAAENMMMMCGGYMWFCNITKILK...........tW....NNA....S.DpkWY.PWS......................QCRLRQNVDDWMKVGRRIYLPPQPGfnnRIRCTQRVTEMFLEIQKVEN.G.TQVSL.LP...PSDNVNQFVSVASDYKLVELELIGFAPTETQR...YQP.R.------nkrg.........
ENV_HV190/136-500                 .....nstssme----------------------.......--------------..----...------.------.-..--..-..--..----------------------------------.-----..-.--------------.----------------..-----..--AGGELTNCSFNVTtVLRDK.QQKVHALFYR.....LDV...VPID........N...N..S.....-..-...T..Q...YrLINCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGL-CTNVSTVQCTHGIRPVVSTQLLLNGSLAEEQIIIRT..K..NI.......sDN.tKN...II.vQLKT--PVNITCTRPNNNTR.TSIHLGPGr..aFYAT..G...D..I...IGD..-IRQAHCNISrTDWNKTLHQVVTQLG..........IH....-..----........-LNN.............RTISF.-.KPNSGGDMEVRTHSFNCRGEFFYCNTSGLFNs..........sWemhtNYT....S.N..DT.KGNen.................itlPCRIKQIVNMWQRVGRAMYAPPIQG...NIMCVSNITGLILTIDEGNA.S.AE-NY.TFrpgGGDMRDNWRSELYKYKVVKIEPLGIAPTKTRR...--R.V.VEREKR.............
A0A1B4WRK4_SIV/24-543             ............LYVTVFYGVPVWKNSTVQAFCM.......TPTNRLWATTNCIP..DDHD...YTEVPL.NITEPF.E..AWadR..NP..LVAQAGSNIHLLFEQTLKPCVKLSPLCIKMSCVP.LNGSK..T.G--STTAPSTTQTTkSTQRPCKQYEKNNTLQacNDTIIerEMDEEPASNCTFAMA.GYIRD.QKKNYSVVWD.....DRE...IYCK........N...G..SdnsskV..K...E..C...Y.MIHCNDSVIKEACDKTYWDELRLRYCAPAGYALLKCNDHDYNGYKQNCSNVSVVHCTGLMNTTVSTGLLLNGSYSENRTQIWQ..K..HR.......vNN.dSV...II..LFNKFYNLTVTCKRPGNKTV.LPVTIMAG....LVFH..S...Q..K...YNM..RLRQAWCHFQ.GNWKGAWKEVREEIV..........KL....PkdRYQG........TNNT.............EQIKL.L.RQ--DGDPEAANLWFNCQGEFFYCKMDWFLN............Y....INN....A.T..TTfDGNkcgnktkkgn.apgpcvqrtyvACHIRSVVNDWYTVSKLTYAPPREG...HLQCTSTVTGMTVELNY-NN.K.NVTNV.TL...SPQIEGIWAAELGRYKLVEITPIGFAPTEVRR...YTG.G.HERQKR.............
ENV_HV1A2/33-509                  ............LWVTVYYGVPVWKEATTTLFCAsdaraydTEVHNVWATHACVP..TDPN...PQEVVLgNVTENF.N..MW..K..NN..MVEQMQEDIISLWDQSLKPCVKLTPLCVTLNCTD.LGKAT..N.T-------------.NSSNWK--EEI-----..-----..---KGEIKNCSFNITtSIRDK.IQKENALFRN.....LDV...VPID........N...A..S.....T..TtnyT..N...YrLIHCNRSVITQACPKVSFEPIPIHYCTPAGFAILKCNNKTFNGKGP-CTNVSTVQCTHGIRPIVSTQLLLNGSLAEEEVVIRS..D..NF.......tNN.aKT...II.vQLNE--SVAINCTRPNNNTR.KSIYIGPGr..aFHTT..G...R..I...IGD..-IRKAHCNISrAQWNNTLEQIVKKLR..........EQ....-..----........FGNN.............KTIVF.-.NQSSGGDPEIVMHSFNCRGEFFYCNTTQLFNn..........tW...rLNH....T.E..GT.KGNdt.................iilPCRIKQIINMWQEVGKAMYAPPIGG...QISCSSNITGLLLTRDGGTN.VtNDTEV.-FrpgGGDMRDNWRSELYKYKVIKIEPLGIAPTKAKR...--R.V.VQREKR.............
ENV_HV2RO/21-511                  ............QYVTVFYGVPTWKNATIPLFCA.......TRNRDTWGTIQCLP..DNDD...YQEITL.NVTEAF.D..AW..N..NT..VTEQAIEDVWHLFETSIKPCVKLTPLCVAMKCSS.TESST..G.NNTTSKSTSTTTTT.PTDQEQEISEDTPCAR..ADNCS..GLGEEETINCQFNMT.GLERD.KKKQYNETWY.....SKD...VVCEt......nN...S..T.....N..Q...T.qC...Y.MNHCNTSVITESCDKHYWDAIRFRYCAPPGYALLRCNDTNYSGFAPNCSKVVASTCTRMMETQTSTWFGFNGTRAENRTYIYW..H..GR........DN..RT...II..SLNKYYNLSLHCKRPGNKTV.KQIMLMSG....HVFH..Sh.yQ..P...INK..RPRQAWCWFK.GKWKDAMQEVKETLA..........KH....P..RYRG........TNDT.............RNISF.A.APGKGSDPEVAYMWTNCRGEFLYCNMTWFLN............W....IEN....K.T..HR.NYA......................PCHIKQIINTWHKVGRNVYLPPREG...ELSCNSTVTSIIANIDWQN-.N.NQTNI.TF...SAEVAELYRLELGDYKLVEITPIGFAPTKEKR...YSS.A.HGRHTR.............
Q9Q6V8_9HIV1/30-144               ............LWVTVYYGVPVWKEATTTLFCAsdakaysKEVHNVWATYACVP..TDPS...PQEIPLkNVTENF.N..MG..K..NN..MVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTD.LKKEV..T.STNT----------.----------------..-----..---------------.-----.----------.....---...----........-...-..-.....-..-...-..-...-.-----------------------------------------------------------------------------------..-..--........--..--...--..--------------------.--------....----..-...-..-...---..----------.---------------..........--....-..----........----.............-----.-.-------------------------------............-....---....-.-..--.---......................-------------------------...--------------------.-.-----.--...--------------------------------...---.-.------ssikm........
C7TQ97_9HIV1/33-147               ............LWVTVYYGVPVWRDAETTLFCAsdakaydTEVHNVWATHACVP..TDPN...PQEMNLtNVTEYF.N..MW..K..NN..MVEQMHADIISLWDQSLKPCVKLTPLCVTLNCTD.ITTNR..T.SRN-----------.----------------..-----..---------------.-----.----------.....---...----........-...-..-.....-..-...-..-...-.-----------------------------------------------------------------------------------..-..--........--..--...--..--------------------.--------....----..-...-..-...---..----------.---------------..........--....-..----........----.............-----.-.-------------------------------............-....---....-.-..--.---......................-------------------------...--------------------.-.-----.--...--------------------------------...---.-.------htdinr.......
ENV_HV1MV/35-523                  ............LYATVYSGVPVWEEAAPVLFCAsdanltsTEQHNIWASQACVP..TDPN...PHEFPLgNVTDNF.D..IW..K..NY..MVDQMHEDIISLWEQSLKPCEKMTFLCVQMNCVD.LQTNK..T.G-------------.------LLNETI----..-----..----NEMRNCSFNVT.TVLTD.KKEQKQALFY.....VSDlskVNDS........N...A..V.....N..G...T..T...YmLTNCNSTIIKQACPKVSFEPIPIHYCAPTGYAIFKCNDTDFNGTGL-CHNISVVTCTHGIKPTVSTQLILNGTLSREKIRIMG..K..NIt......eSA..KN...II.vTLNT--PINMTCIREGIAEV.QDIYTGPMr.wrSMTL..K...R..S...NNTspRSRVAYCTYNkTVWENALQQTAIRYL..........NL....-..--VN........QTEN.............VTIIF.-.SRTSGGDAEVSHLHFNCHGEFFYCNTSGMFNytfinctksgcqE....IKG....S.N..ET.NKNg...................tiPCKLRQLVRSWMKGESRIYAPPIPG...NLTCHSNITGMILQLDQPWN.S.TGENT.LRp.vGGDMKDIWRTKLYNYKVVQIKPFSVAPTKMSRpiiNIH.T.PHREKR.............
Q9YX49_9HIV1/33-144               ............LWVTVYYGVPVWRDAETTLFCAseakayeKEVHNIWATHACVP..TDPN...PQEVALiNVTENF.N..MW..K..ND..MVEQMHEDIISLWNEGLKPCAKLTSLCVTFTCIN.ATTTN..S.T-------------.----------------..-----..---------------.-----.----------.....---...----........-...-..-.....-..-...-..-...-.-----------------------------------------------------------------------------------..-..--........--..--...--..--------------------.--------....----..-...-..-...---..----------.---------------..........--....-..----........----.............-----.-.-------------------------------............-....---....-.-..--.---......................-------------------------...--------------------.-.-----.--...--------------------------------...---.-.------ngtvi........
ENV_HV1B9/33-508                  ...........t-WVTIYYGVPVWREATTTLFCAsdakaydTEVHNVWATHACVP..TDPN...PQEVVLgNVTENF.N..MW..K..NN..MVDQMHEDIISLWDESLKPCVKLTPLCVTLNCTN.LNITK..N.TTN-----------.PTSSSWGMMEKG----..-----..-----EIKNCSFYITtSIRNK.VKKEYALFNR.....LDV...VPIE........N...T..N.....-..N...T..K...YrLISCNTSVITQACPKVSFQPIPIHYCVPAGFAMLKCNNKTFNGSGP-CTNVSTVQCTHGIRPVVSTQLLLNGSLAEEDIVIRS..E..NF.......tDN.aKT...II.vQLNE--SVVINCTRPNNNTR.RRLSIGPG....RAFY..A...RrnI...IG-..DIRQAHCNISrAKWNNTLQQIVIKLR..........EK....-..----........-FRN.............KTIAF.-.NQSSGGDPEIVMHSFNCGGEFFYCNTAQLFNs..........tWn..vTGG....T.N..GT.EGNdi.................itlQCRIKQIINMWQKVGKAMYAPPITG...QIRCSSNITGLLLTRDGGNStE.TETEI.-FrpgGGDMRDNWRSELYKYKVVRIEPIGVAPTRAKR...--R.T.VQREKR.............
#=GR ENV_HV1B9/33-508       SS    ...........X-XXXXXXXXXXXX------B------TT--SHHHHHHHHH---..----...S--EE-TT--EEE.E..GG..G..-H..HHHHHHHHHHHHHHHSS--SEEESXXXXXXXXXX.XXXXX..X.XXX-----------.XXXXXXXXXXXX----..-----..-----XXXXXXXXXXXXXXXX.XXXXXXXXXX.....XXX...XXXX........X...X..X.....-..X...X..X...XXXXXXSS-EEE------------B--B--TT--EEEE--SS--SEEE-ESSEEEESB---B----BSSEEES----SSS-EEE-..S..-S.......S-T.TSE...EE.EEEEE--EEEEEEEE------.--------....----..-...----...---..---EEEEEEEHHHHHHHHHHHHHHHH..........HH....-..----........-TSS.............--EEE.-.----SB-HHHHTEEEESSS-EEEE--TTTS--..........EE-..----....-.-..--.--SSE.................EEEEEEB-SEEE-SSSS-EEE-----SS...-EEEEEEEEEEEEEE---SSS-.-S-EE.-EEE----THHHHHTTSSSEE-XXXXXXXXXXXXXXX...--X.X.XXXXXX.............
ENV_HV1AN/34-142                  ............LYATVYAGVPVWEDATPVLFCAsdanltsTEKHNIWASQACVP..TDPT...PYEYPLhNVTDDF.N..IW..K..NY..MVEQMQEDIISLWDQSLKPCVQMTFLCVQMECTN.IAGTT..N.E-------------.----------------..-----..---------------.-----.----------.....---...----........-...-..-.....-..-...-..-...-.-----------------------------------------------------------------------------------..-..--........--..--...--..--------------------.--------....----..-...-..-...---..----------.---------------..........--....-..----........----.............-----.-.-------------------------------............-....---....-.-..--.---......................-------------------------...--------------------.-.-----.--...--------------------------------...---.-.------nl...........
ENV_SIVTN/23-502                  ...........y-YTTVFYGVPVWKEAQPTLFCAsdaditsRDKHNIWATHNCVP..LDPN...PYEVTLaNVSIRF.N..ME..E..NY..MVQEMKEDILSLFQQSFKPCVKLTPFCIKMTCTM.----T..N.TTNKTLNSATTTLT.PTVNLSSI--------..-----..--PNYEVYNCSFNQTtEFRDK.KKQIYSLFYR.....EDI...VKED........G...N..N.....-..N...S..Y...Y.LHNCNTSVITQECDKSTFEPIPIRYCAPAGFALLKCRDQNFTGKGQ-CSNVSVVHCTHGIYPMIATALHLNGSLEEEETKAYF..V..NT........SV..NT...PLlvKFNV--SINLTCERTGNNTR.GQVQIGPG....MTFY..N...I..-...ENVvgDTRKAYCSVNaTTWYRNLDWAMAAIN..........TT....-..-MRA........RNET.............VQQTF.-.QWQRDGDPEVTSFWFNCQGEFFYCNLTNWTN...........tW...tANR....T.N..NT.HGTl...................vaPCRLRQIVNHWGIVSKGVYLPPRRG...TVKCHSNITGLIMTAEKDNN.N.SYTPQ.-F...SAVVEDYWKVELARYKVVEIQPLSVAPRPGKR...---.-.------peikanhtrsrr.
ENV_HV192/33-146                  ............LWVTVYYGVPVWKEAKTTLFCAsdakaydAEVHNVWATHACVP..TDPN...PQEMVLeNVTENF.N..MW..E..ND..MVEQMHQDIISLWDQSLKPCVKLTPLCVTLHCSN.RTIDY..N.--------------.----------------..-----..---------------.-----.----------.....---...----........-...-..-.....-..-...-..-...-.-----------------------------------------------------------------------------------..-..--........--..--...--..--------------------.--------....----..-...-..-...---..----------.---------------..........--....-..----........----.............-----.-.-------------------------------............-....---....-.-..--.---......................-------------------------...--------------------.-.-----.--...--------------------------------...---.-.------nrtdnmgg.....
ENV_HV2BE/24-510                  ............QYVTVFYGIPAWKNASIPLFCA.......TKNRDTWGTIQCLP..DNDD...YQEIIL.NVTEAF.D..AW..N..NT..VTEQAVEDVWHLFETSIKPCVKLTPLCVAMNCSR.VQGNT..T.TPNPRTSSSTTSRP.PTSAASIINETSNCIE..NNTCA..GLGYEEMMQCEFNMK.GLEQD.KKRRYKDTWY.....LED...VVCD........N...T..T.....A..G...T..C...Y.MRHCNTSIIKESCDKHYWDAMRFRYCAPPGFALLRCNDTNYSGFEPKCTKVVAASCTRMMETQTSTWFGFNGTRAENRTYIYW..H..GR........DN..RT...II..SLNKYYNLTMRCKRPGNKTV.LPITLMSG....LVFH..S...Q..P...INT..RPRQAWCRFG.GRWREAMQEVKQTLV..........QH....P..RYKG........INDT.............GKINF.T.KPGAGSDPEVAFMWTNCRGEFLYCNMTWFLN............W....VED....K.N..QT.RRN......................YCHIKQIINTWHKVGKNVYLPPREG...ELACESTVTSIIANIDIDKN.R.THTNI.TF...SAEVAELYRLELGDYKLIEITPIGFAPTDQRR...YSS.T.PVRNKR.............
#=GC SS_cons                      ...........XSSXXXXEEEXXEEE-----EEE----TT-ESHHHHHHHHC-EE..--SS...S-EEEETSEEEEE.E..SS..S..TH..HHHHHHHHHHHHHHHHS--SEEEECCSSSEEEEE.XTTXX..E.EXX-----------.EEEETTTTEEEE----..-----..-----EEEXSSSXXXSSEEEE.EEEEEXTTSX.....EEE...EEEX........X...S..S.....-..X...X..X...XTTXSXSSCEEEEE--SEEEEE-EBEEB--TTEEEEEE--TT--SEEEEESSEEEESB---BESSEBSSEEESSS--SSS-EEEE..S..TS.......SST.TSE...EE.EEEEECCEEEEEEEESCCGSS.SSBS-TTTCTBCCCHH..C...H--H...CSC..-CTEEEEEEEHHHHHHHHHHHHHHHH..........HH....T..T--S........STST.............SEEEE.E.--STSBSHHHHTEEEEETTEEEEEETTTTCHEEE.....SSHECS..CHTC....C.C..CT.CCSSEG................EEEEEEEESEEEGSSSSEEEEEE--TSS...TEEEEEEEEEEEEEEESSSSST.SSEEE.EEEESBSSTHHHHHHHHTTEEEEEEXSXEEEXXXXXX...--X.X.XXXXXX.............
#=GC seq_cons                     .............aVTVaYGVPVW+pApssLFCA.......Tcs+slWuTpsClP..s-ss....pEh.L.NVTEsF.s..hW..c..Np..hV-QhtpDlhsLa-poLKPCVKLTPLCVphpCsp.hptpp..s.s............................................phhsCpFNhT.tlpcc.hpp.as.hah......c....lshp........N...s..s............p..p...Y.hhpCNTSsIppuCsKh.a-sI.l+YCAPsGaAlLKCNspsasGht..CpNVSsVpCT+hhcsslSTthhlNGohu-pphhIh...p..sh........ss..ps...II..pLsp..slplpCpRPsNpTh.htlplhsG....hhhh..u...p......hs.....RpAaCphs.spWppshpplttpl...........p......................ss.............ppI.F...t.spGGD.Elshh.hNCtGEFFYCNho.hhN..................tt....p.s..to.ttt....................hhsC+I+QIls.WtpVG+shYhPPhtG...plpCpSslTullhsh-hspp.t.spsph..h...uuphps.WRtELhcYKlVcIcPlGlAPTcs+R.....p.s.spRpKR.............
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