GenomeNet

Database: Pfam
Entry: Glyco_transf_22
LinkDB: Glyco_transf_22
Original site: Glyco_transf_22 
#=GF ID   Glyco_transf_22
#=GF AC   PF03901.19
#=GF DE   Alg9-like mannosyltransferase family
#=GF PI   PMP; 
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   DOMO:DM04662 & Pfam-B_7750 (Release 8.0)
#=GF GA   23.80 23.80;
#=GF TC   23.80 23.80;
#=GF NC   23.60 23.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0111
#=GF RN   [1]
#=GF RM   12030331
#=GF RT   A mannosyltransferase gene at 11q23 is disrupted by a
#=GF RT   translocation breakpoint that co-segregates with bipolar
#=GF RT   affective disorder in a small family. 
#=GF RA   Baysal BE, Willett-Brozick JE, Badner JA, Corona W, Ferrell RE,
#=GF RA   Nimgaonkar VL, Detera-Wadleigh SD; 
#=GF RL   Neurogenetics 2002;4:43-53.
#=GF RN   [2]
#=GF RM   12200473
#=GF RT   Common origin and evolution of glycosyltransferases using
#=GF RT   Dol-P-monosaccharides as donor substrate. 
#=GF RA   Oriol R, Martinez-Duncker I, Chantret I, Mollicone R, Codogno P; 
#=GF RL   Mol Biol Evol 2002;19:1451-1463.
#=GF RN   [3]
#=GF RM   10954751
#=GF RT   Critical roles of glycosylphosphatidylinositol for Trypanosoma
#=GF RT   brucei. 
#=GF RA   Nagamune K, Nozaki T, Maeda Y, Ohishi K, Fukuma T, Hara T,
#=GF RA   Schwarz RT, Sutterlin C, Brun R, Riezman H, Kinoshita T; 
#=GF RL   Proc Natl Acad Sci U S A 2000;97:10336-10341.
#=GF RN   [4]
#=GF RM   9576863
#=GF RT   Saccharomyces cerevisiae GPI10, the functional homologue of
#=GF RT   human PIG-B, is required for glycosylphosphatidylinositol-anchor
#=GF RT   synthesis. 
#=GF RA   Sutterlin C, Escribano MV, Gerold P, Maeda Y, Mazon MJ,
#=GF RA   Kinoshita T, Schwarz RT, Riezman H; 
#=GF RL   Biochem J 1998;332:153-159.
#=GF DR   INTERPRO; IPR005599;
#=GF DR   CAZY; GT22;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Members of this family are mannosyltransferase enzymes [1-2]. 
#=GF CC   At least some members are localised in endoplasmic reticulum and
#=GF CC   involved in GPI anchor biosynthesis [3-4].
#=GF SQ   6425
#=GS F0ZDL0_DICPU/962-1377       AC F0ZDL0.1
#=GS A0A194S6X5_RHOGW/65-555     AC A0A194S6X5.1
#=GS A0A5J9W9M5_9POAL/140-243    AC A0A5J9W9M5.1
#=GS G9NW63_HYPAI/11-415         AC G9NW63.1
#=GS A0A2P5Y4C8_GOSBA/154-246    AC A0A2P5Y4C8.1
#=GS E9DUF2_METAQ/1-424          AC E9DUF2.1
#=GS A0A195FWD3_9HYME/8-401      AC A0A195FWD3.1
#=GS A0A398A8X7_BRACM/43-454     AC A0A398A8X7.1
#=GS A0A6A7L945_9BACT/121-481    AC A0A6A7L945.1
#=GS A0A397J804_9GLOM/27-491     AC A0A397J804.1
#=GS A0A061DVS4_THECC/13-398     AC A0A061DVS4.1
#=GS A0A319CH76_9EURO/37-463     AC A0A319CH76.1
#=GS A0A4E0RTL1_FASHE/23-154     AC A0A4E0RTL1.1
#=GS A0A1L9UPE3_ASPBC/38-464     AC A0A1L9UPE3.1
#=GS B9SBK6_RICCO/46-450         AC B9SBK6.1
#=GS A0A3Q7RKB5_VULVU/2-406      AC A0A3Q7RKB5.1
#=GS A0A0K6G9G7_9AGAM/1-218      AC A0A0K6G9G7.1
#=GS A0A437AVV4_CHISP/21-499     AC A0A437AVV4.1
#=GS A0A2H3IKP3_9EURO/4-395      AC A0A2H3IKP3.1
#=GS A0A4U5V546_COLLU/62-484     AC A0A4U5V546.1
#=GS A0A1X0SAJ8_RHIZD/6-396      AC A0A1X0SAJ8.1
#=GS M3CY86_SPHMS/1-450          AC M3CY86.1
#=GS M7TMT7_EUTLA/4-214          AC M7TMT7.1
#=GS A0A392NXE1_9FABA/1-52       AC A0A392NXE1.1
#=GS A0A3P9NRR8_POERE/11-252     AC A0A3P9NRR8.1
#=GS A0A090N3J8_OSTTA/22-418     AC A0A090N3J8.1
#=GS J3M024_ORYBR/20-408         AC J3M024.1
#=GS V5G140_BYSSN/37-463         AC V5G140.1
#=GS A0A5A8CMH6_CAFRO/15-491     AC A0A5A8CMH6.1
#=GS F4WHA6_ACREC/43-468         AC F4WHA6.1
#=GS A0A0V1CP06_TRIBR/6-399      AC A0A0V1CP06.1
#=GS A0A090N2X0_OSTTA/7-430      AC A0A090N2X0.1
#=GS A0A179IUK4_CORDF/12-477     AC A0A179IUK4.1
#=GS A0A1S3WX34_ERIEU/65-487     AC A0A1S3WX34.1
#=GS A0A091UHM5_PHORB/1-381      AC A0A091UHM5.1
#=GS Q4WQI0_ASPFU/6-426          AC Q4WQI0.1
#=GS A0A2P4SYJ6_BAMTH/164-307    AC A0A2P4SYJ6.1
#=GS A0A455C821_PHYMC/52-435     AC A0A455C821.1
#=GS K9DHB6_9BURK/262-394        AC K9DHB6.1
#=GS A0A1X6MMT2_9APHY/4-422      AC A0A1X6MMT2.1
#=GS A0A178AXG8_9PLEO/4-398      AC A0A178AXG8.1
#=GS A0A4U0VB70_9PEZI/4-395      AC A0A4U0VB70.1
#=GS A0A6A3BT69_HIBSY/32-439     AC A0A6A3BT69.1
#=GS A0A1X7R1S3_9SACH/6-393      AC A0A1X7R1S3.1
#=GS A0A367KTW7_RHIST/4-401      AC A0A367KTW7.1
#=GS C3XS04_BRAFL/443-620        AC C3XS04.1
#=GS A0A453CKC3_AEGTS/4-129      AC A0A453CKC3.1
#=GS K5VWP2_AGABU/7-430          AC K5VWP2.1
#=GS A0A2K3QAI4_9HYPO/22-488     AC A0A2K3QAI4.1
#=GS H6BNX1_EXODN/52-584         AC H6BNX1.1
#=GS C4R5V3_KOMPG/5-383          AC C4R5V3.1
#=GS A0A2K5DDZ2_AOTNA/60-489     AC A0A2K5DDZ2.1
#=GS A0A1J7J3P4_9PEZI/7-409      AC A0A1J7J3P4.1
#=GS A0A0V1CC76_TRIBR/310-699    AC A0A0V1CC76.1
#=GS A0A3D8QSQ7_9HELO/40-530     AC A0A3D8QSQ7.1
#=GS A0A341C5B2_NEOAA/60-334     AC A0A341C5B2.1
#=GS A0A1S3RNQ6_SALSA/76-498     AC A0A1S3RNQ6.1
#=GS A0A1D6E4B8_MAIZE/1-146      AC A0A1D6E4B8.1
#=GS A0A3M2S1Q2_9HYPO/22-488     AC A0A3M2S1Q2.1
#=GS A0A1E3NKB9_9ASCO/26-408     AC A0A1E3NKB9.1
#=GS A0A1J9RIY9_9PEZI/20-447     AC A0A1J9RIY9.1
#=GS A0A4T0FE73_9BASI/1021-1457  AC A0A4T0FE73.1
#=GS A0A2I2F0H1_9EURO/36-462     AC A0A2I2F0H1.1
#=GS A0A098VQH3_9MICR/5-400      AC A0A098VQH3.1
#=GS A0A2K3Q4P0_9HYPO/34-467     AC A0A2K3Q4P0.1
#=GS A0A2P6VBG0_9CHLO/10-384     AC A0A2P6VBG0.1
#=GS A0A2T0FJT6_9ASCO/14-390     AC A0A2T0FJT6.1
#=GS H2V3V8_TAKRU/62-484         AC H2V3V8.1
#=GS A0A369SID3_9METZ/39-82      AC A0A369SID3.1
#=GS A0A0L7QSA1_9HYME/25-468     AC A0A0L7QSA1.1
#=GS A0A437B735_CHISP/33-413     AC A0A437B735.1
#=GS K1RH37_CRAGI/42-196         AC K1RH37.1
#=GS A0A0D9YAW7_9ORYZ/184-488    AC A0A0D9YAW7.1
#=GS A0A0Q3EBY4_BRADI/21-408     AC A0A0Q3EBY4.1
#=GS A0A2X0MKB0_9BASI/36-480     AC A0A2X0MKB0.1
#=GS A0A226NHK1_CALSU/69-143     AC A0A226NHK1.1
#=GS A0A0V0ZM19_9BILA/6-399      AC A0A0V0ZM19.1
#=GS G3QBN1_GASAC/62-484         AC G3QBN1.1
#=GS A0A430QPY0_SCHBO/274-724    AC A0A430QPY0.1
#=GS A0A1Q2YH00_9ASCO/1-215      AC A0A1Q2YH00.1
#=GS A0A4R8RNS9_COLTR/134-324    AC A0A4R8RNS9.1
#=GS A0A093LDG6_FULGA/12-408     AC A0A093LDG6.1
#=GS A0A0L6VSM2_9BASI/9-202      AC A0A0L6VSM2.1
#=GS A0A4Q4XSM7_9PEZI/11-390     AC A0A4Q4XSM7.1
#=GS A0A1I7K8J7_9BACT/41-434     AC A0A1I7K8J7.1
#=GS A0A446PJM9_TRITD/50-429     AC A0A446PJM9.1
#=GS A0A421JI16_9ASCO/9-382      AC A0A421JI16.1
#=GS C7YYQ1_NECH7/23-484         AC C7YYQ1.1
#=GS A0A2K6V197_SAIBB/15-406     AC A0A2K6V197.1
#=GS A0A316ZHN4_9BASI/29-522     AC A0A316ZHN4.1
#=GS F9XD49_ZYMTI/2-431          AC F9XD49.1
#=GS A0A1G4MGC9_LACFM/6-395      AC A0A1G4MGC9.1
#=GS A0A3M6V1C1_9CNID/8-457      AC A0A3M6V1C1.1
#=GS A0A553I3K3_9PEZI/210-460    AC A0A553I3K3.1
#=GS A0A094H5Z2_9PEZI/47-407     AC A0A094H5Z2.1
#=GS A0A225A939_9EURO/36-528     AC A0A225A939.1
#=GS A0A2K3MRM1_TRIPR/19-213     AC A0A2K3MRM1.1
#=GS A0A2S4L2M5_9HYPO/11-414     AC A0A2S4L2M5.1
#=GS A0A3F2Y6L2_DEKBR/26-417     AC A0A3F2Y6L2.1
#=GS K0KHY8_WICCF/7-410          AC K0KHY8.1
#=GS B2B3L9_PODAN/44-471         AC B2B3L9.1
#=GS A0A2Y9T9X1_PHYMC/90-437     AC A0A2Y9T9X1.1
#=GS A0A0E0JKE3_ORYPU/45-453     AC A0A0E0JKE3.1
#=GS A0A178DQE0_9PLEO/28-465     AC A0A178DQE0.1
#=GS G8ZLA5_TORDC/9-412          AC G8ZLA5.1
#=GS A0A453MTE9_AEGTS/61-473     AC A0A453MTE9.1
#=GS Q7QFX4_ANOGA/4-395          AC Q7QFX4.4
#=GS A0A428NP27_9HYPO/25-491     AC A0A428NP27.1
#=GS A0A484C734_PERFV/11-243     AC A0A484C734.1
#=GS A0A0Q8FI92_9GAMM/258-396    AC A0A0Q8FI92.1
#=GS C3ZIX8_BRAFL/332-469        AC C3ZIX8.1
#=GS B8BXY1_THAPS/13-438         AC B8BXY1.1
#=GS A0A1V8SN62_9PEZI/12-405     AC A0A1V8SN62.1
#=GS A0A0E0FID0_ORYNI/217-426    AC A0A0E0FID0.1
#=GS H6QP65_PUCGT/4-316          AC H6QP65.1
#=GS A0A2T4AA65_TRIHA/61-493     AC A0A2T4AA65.1
#=GS V5EQG4_KALBG/64-522         AC V5EQG4.1
#=GS A0A401GIY2_9APHY/4-412      AC A0A401GIY2.1
#=GS A0A444GAK7_ENSVE/106-169    AC A0A444GAK7.1
#=GS A0A368F5L5_ANCCA/75-182     AC A0A368F5L5.1
#=GS A0A1S8B7M5_9PEZI/37-222     AC A0A1S8B7M5.1
#=GS A0A0L7L9E7_9NEOP/3-149      AC A0A0L7L9E7.1
#=GS A0A485NZU1_LYNPA/38-364     AC A0A485NZU1.1
#=GS A0A482V0B0_9CUCU/372-513    AC A0A482V0B0.1
#=GS A0A077YZH7_TRITR/150-347    AC A0A077YZH7.1
#=GS S3E334_GLAL2/44-534         AC S3E334.1
#=GS A0A3P8W370_CYNSE/11-392     AC A0A3P8W370.1
#=GS T1F256_HELRO/6-448          AC T1F256.1
#=GS A0A016VDL6_9BILA/50-319     AC A0A016VDL6.1
#=GS A0A397TQQ0_9GLOM/6-408      AC A0A397TQQ0.1
#=GS A0A284QW65_ARMOS/2-427      AC A0A284QW65.1
#=GS A0A4X2LX86_VOMUR/60-482     AC A0A4X2LX86.1
#=GS A0A091PWJ0_LEPDC/1-349      AC A0A091PWJ0.1
#=GS A0A096NKU8_PAPAN/13-406     AC A0A096NKU8.2
#=GS A0A3N4KJ33_9PEZI/8-398      AC A0A3N4KJ33.1
#=GS B2AWJ9_PODAN/4-224          AC B2AWJ9.1
#=GS D0NCQ5_PHYIT/2-447          AC D0NCQ5.1
#=GS A0A1X2HXE3_9FUNG/57-532     AC A0A1X2HXE3.1
#=GS G1PDT2_MYOLU/16-290         AC G1PDT2.1
#=GS A0A0B2WDD8_METAS/10-412     AC A0A0B2WDD8.1
#=GS A0A075LW71_9EURY/249-407    AC A0A075LW71.1
#=GS A0A2R9BX87_PANPA/1-318      AC A0A2R9BX87.1
#=GS A0A1U8LQ03_GOSHI/189-574    AC A0A1U8LQ03.1
#=GS A0A1Y3BBM7_EURMA/8-438      AC A0A1Y3BBM7.1
#=GS A0A287IZ82_HORVV/2-218      AC A0A287IZ82.1
#=GS A0A162VKV4_DIDRA/5-432      AC A0A162VKV4.1
#=GS D5GEE1_TUBMM/4-400          AC D5GEE1.1
#=GS A0A0Q3E7M2_BRADI/21-415     AC A0A0Q3E7M2.1
#=GS A0A673XAH6_SALTR/31-460     AC A0A673XAH6.1
#=GS A0A5A8CLY2_CAFRO/315-557    AC A0A5A8CLY2.1
#=GS F6ZPT6_MACMU/645-856        AC F6ZPT6.3
#=GS W6KG87_9TRYP/18-474         AC W6KG87.1
#=GS A0A5A7TYM1_CUCME/43-419     AC A0A5A7TYM1.1
#=GS A0A096PBU4_OSTTA/7-408      AC A0A096PBU4.1
#=GS A0A6I8USK5_DROPS/75-498     AC A0A6I8USK5.1
#=GS A0A151S9D7_CAJCA/33-439     AC A0A151S9D7.1
#=GS A0A4P9X5K3_9FUNG/58-551     AC A0A4P9X5K3.1
#=GS A0A1U8HH76_GOSHI/2-143      AC A0A1U8HH76.1
#=GS A0A5N6KI62_9HELO/8-414      AC A0A5N6KI62.1
#=GS A0A4Q4WPU6_9PEZI/926-1321   AC A0A4Q4WPU6.1
#=GS A0A1L9AUF9_9DELT/38-381     AC A0A1L9AUF9.1
#=GS A0A0E0FIC9_ORYNI/45-225     AC A0A0E0FIC9.1
#=GS A0A0T6BCR1_9SCAR/19-241     AC A0A0T6BCR1.1
#=GS A0A2Z6RSC3_9GLOM/9-458      AC A0A2Z6RSC3.1
#=GS A0A0D9VB89_9ORYZ/47-127     AC A0A0D9VB89.1
#=GS A0A4V6Y8B3_SETVI/48-453     AC A0A4V6Y8B3.1
#=GS A0A2V1CRT5_9HELO/9-417      AC A0A2V1CRT5.1
#=GS A6R052_AJECN/1-115          AC A6R052.1
#=GS A0A672ZQA5_9TELE/233-457    AC A0A672ZQA5.1
#=GS A0A1E5RQH6_HANUV/28-494     AC A0A1E5RQH6.1
#=GS A1D229_NEOFI/27-453         AC A1D229.1
#=GS A0A3N4J8S6_9PEZI/52-474     AC A0A3N4J8S6.1
#=GS E2C1W4_HARSA/9-398          AC E2C1W4.1
#=GS A0A453MT65_AEGTS/60-262     AC A0A453MT65.1
#=GS W7TF04_9STRA/8-424          AC W7TF04.1
#=GS A0A317SUP5_9PEZI/4-403      AC A0A317SUP5.1
#=GS A0A4D8Z1T0_SALSN/43-447     AC A0A4D8Z1T0.1
#=GS A0A453MTA7_AEGTS/1-180      AC A0A453MTA7.1
#=GS A0A087X7Y3_POEFO/1-355      AC A0A087X7Y3.2
#=GS A0A1L9RZV1_ASPWE/7-424      AC A0A1L9RZV1.1
#=GS A0A484GI70_SOUCH/60-482     AC A0A484GI70.1
#=GS K0KJP1_WICCF/34-419         AC K0KJP1.1
#=GS W7I1N2_9PEZI/46-327         AC W7I1N2.1
#=GS A0A369KDB4_HYPMA/7-419      AC A0A369KDB4.1
#=GS A0A0A2IF70_PENEN/31-457     AC A0A0A2IF70.1
#=GS A0A0G4P4D4_PENCA/10-435     AC A0A0G4P4D4.1
#=GS A0A0U1LZ35_TALIS/153-360    AC A0A0U1LZ35.1
#=GS A0A1B9IEX4_9TREE/19-465     AC A0A1B9IEX4.1
#=GS A0A015KU12_RHIIW/6-410      AC A0A015KU12.1
#=GS G3PTI7_GASAC/33-434         AC G3PTI7.1
#=GS A0A0D2VF49_GOSRA/53-458     AC A0A0D2VF49.1
#=GS A8Q2X2_MALGO/13-367         AC A8Q2X2.1
#=GS A0A136J2Q9_9PEZI/7-385      AC A0A136J2Q9.1
#=GS A0A665WTL8_ECHNA/12-405     AC A0A665WTL8.1
#=GS G4LYS9_SCHMA/6-452          AC G4LYS9.1
#=GS H2ASU9_KAZAF/8-423          AC H2ASU9.1
#=GS A0A2G5BF87_COERN/1-389      AC A0A2G5BF87.1
#=GS A0A2I0UPH0_LIMLA/39-389     AC A0A2I0UPH0.1
#=GS E0VFI0_PEDHC/88-533         AC E0VFI0.1
#=GS A0A0H2RZD8_9AGAM/5-417      AC A0A0H2RZD8.1
#=GS H9GBK2_ANOCA/282-704        AC H9GBK2.2
#=GS A0A674CLC0_SALTR/43-425     AC A0A674CLC0.1
#=GS A0A1U7U1W6_CARSF/52-438     AC A0A1U7U1W6.1
#=GS A0A5E4R2B7_9NEOP/173-263    AC A0A5E4R2B7.1
#=GS A0A1J1ILD4_9DIPT/3-396      AC A0A1J1ILD4.1
#=GS A0A5N5NTR8_9PEZI/4-398      AC A0A5N5NTR8.1
#=GS A0A2P6V8Z9_9CHLO/37-473     AC A0A2P6V8Z9.1
#=GS A5DIB2_PICGU/6-254          AC A5DIB2.2
#=GS A0A162LRM0_CORDF/4-421      AC A0A162LRM0.1
#=GS A0A4Q9PMQ8_9APHY/7-421      AC A0A4Q9PMQ8.1
#=GS A0A5M9K4H0_MONFR/6-207      AC A0A5M9K4H0.1
#=GS I4YDR7_WALMC/6-434          AC I4YDR7.1
#=GS A0A0L7M263_PLAF4/22-624     AC A0A0L7M263.1
#=GS A0A1U7REH1_ALLSI/1-393      AC A0A1U7REH1.1
#=GS A0A0P9EP18_RHOGW/88-477     AC A0A0P9EP18.1
#=GS A0A6G1EJD7_9ORYZ/46-451     AC A0A6G1EJD7.1
#=GS K6ULE7_9APIC/23-118         AC K6ULE7.1
#=GS A0A2P5IG27_9PEZI/59-426     AC A0A2P5IG27.1
#=GS A0A6A4EKA4_9STRA/38-465     AC A0A6A4EKA4.1
#=GS A0A1S9DQ69_ASPOZ/36-461     AC A0A1S9DQ69.1
#=GS A0A0E0JKE6_ORYPU/119-418    AC A0A0E0JKE6.1
#=GS A0A2N1J742_9BASI/4-403      AC A0A2N1J742.1
#=GS A0A1E3IF05_9TREE/70-518     AC A0A1E3IF05.1
#=GS S3CRM4_OPHP1/68-601         AC S3CRM4.1
#=GS A0A5J5F428_9PEZI/4-384      AC A0A5J5F428.1
#=GS G4N3J6_MAGO7/4-398          AC G4N3J6.1
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#=GS A0A656KKJ8_BLUGR/2-429      AC A0A656KKJ8.1
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#=GS A0A287KKF9_HORVV/45-263     AC A0A287KKF9.1
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#=GS A0A0P1BHX9_9BASI/63-360     AC A0A0P1BHX9.1
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#=GS S9X1N8_CAMFR/17-232         AC S9X1N8.1
#=GS A0A165GTT7_XYLHT/4-394      AC A0A165GTT7.1
#=GS A0A5B0NHZ0_PUCGR/60-558     AC A0A5B0NHZ0.1
#=GS A0A0V1GWK6_9BILA/3-405      AC A0A0V1GWK6.1
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