#=GF ID Gtr1_RagA
#=GF AC PF04670.16
#=GF DE Gtr1/RagA G protein conserved region
#=GF AU Waterfield DI;0000-0003-2885-5126
#=GF AU Finn RD;0000-0001-8626-2148
#=GF SE Pfam-B_4577 (release 7.5)
#=GF GA 22.00 22.00;
#=GF TC 22.00 22.00;
#=GF NC 21.90 21.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF CL CL0023
#=GF RN [1]
#=GF RM 1620108
#=GF RT Putative GTP-binding protein, Gtr1, associated with the function
#=GF RT of the Pho84 inorganic phosphate transporter in Saccharomyces
#=GF RT cerevisiae.
#=GF RA Bun-Ya M, Harashima S, Oshima Y;
#=GF RL Mol Cell Biol 1992;12:2958-2966.
#=GF RN [2]
#=GF RM 7499430
#=GF RT Cloning of a novel family of mammalian GTP-binding proteins
#=GF RT (RagA, RagBs, RagB1) with remote similarity to the Ras-related
#=GF RT GTPases.
#=GF RA Schurmann A, Brauers A, Massmann S, Becker W, Joost HG;
#=GF RL J Biol Chem 1995;270:28982-28988.
#=GF RN [3]
#=GF RM 10388807
#=GF RT Saccharomyces cerevisiae putative G protein, Gtr1p, which forms
#=GF RT complexes with itself and a novel protein designated as Gtr2p,
#=GF RT negatively regulates the Ran/Gsp1p G protein cycle through
#=GF RT Gtr2p.
#=GF RA Nakashima N, Noguchi E, Nishimoto T;
#=GF RL Genetics 1999;152:853-867.
#=GF RN [4]
#=GF RM 11073942
#=GF RT Novel G proteins, Rag C and Rag D, interact with GTP-binding
#=GF RT proteins, Rag A and Rag B.
#=GF RA Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T;
#=GF RL J Biol Chem 2001;276:7246-7257.
#=GF DR INTERPRO; IPR006762;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC GTR1 was first identified in S. cerevisiae as a suppressor of a
#=GF CC mutation in RCC1.
#=GF CC Biochemical analysis revealed that Gtr1 is in fact a G protein
#=GF CC of the Ras family. The RagA/B proteins are the human homologues
#=GF CC of Gtr1. Included in this family is the human Rag C, a novel
#=GF CC protein that has been shown to interact with RagA/B [1,2,3,4].
#=GF SQ 5527
#=GS A0A1D3TDB8_PLAMA/342-493 AC A0A1D3TDB8.1
#=GS A0A3P8ZTN9_ESOLU/10-236 AC A0A3P8ZTN9.2
#=GS A0A7L0MYZ3_9PASS/15-241 AC A0A7L0MYZ3.1
#=GS A0A2U3W805_ODORO/60-286 AC A0A2U3W805.1
#=GS A0A026W5R8_OOCBI/4-230 AC A0A026W5R8.1
#=GS Q4CMM8_TRYCC/10-244 AC Q4CMM8.1
#=GS U5HFD0_USTV1/8-267 AC U5HFD0.1
#=GS T2M4N0_HYDVU/44-270 AC T2M4N0.1
#=GS G0S5C4_CHATD/70-290 AC G0S5C4.1
#=GS A0A0G4J1H7_PLABS/33-262 AC A0A0G4J1H7.1
#=GS A0A8C3KI04_9CHAR/6-232 AC A0A8C3KI04.1
#=GS M3WJR9_FELCA/42-296 AC M3WJR9.1
#=GS A0A8D0G691_SPHPU/72-298 AC A0A8D0G691.1
#=GS A0A165QPS3_9APHY/1-206 AC A0A165QPS3.1
#=GS A0A1Y2GR45_9FUNG/4-230 AC A0A1Y2GR45.1
#=GS S3DCN9_GLAL2/69-293 AC S3DCN9.1
#=GS A0A7K6RKX0_9GRUI/1-211 AC A0A7K6RKX0.1
#=GS A0A8B9VIL5_9AVES/47-273 AC A0A8B9VIL5.1
#=GS A0A7E6ETH7_OCTVU/29-255 AC A0A7E6ETH7.1
#=GS A0A8B9EY16_9PSIT/73-299 AC A0A8B9EY16.1
#=GS A0A643BLM0_BALPH/48-104 AC A0A643BLM0.1
#=GS A0A2K6NA94_RHIRO/63-289 AC A0A2K6NA94.1
#=GS A0A194XBI3_9HELO/22-251 AC A0A194XBI3.1
#=GS A0A6P6QUG9_CARAU/5-107 AC A0A6P6QUG9.1
#=GS A0A091DK46_FUKDA/278-493 AC A0A091DK46.1
#=GS A0A8B7SLU1_HIPAR/63-289 AC A0A8B7SLU1.1
#=GS A0A183KR74_9TREM/4-230 AC A0A183KR74.1
#=GS A0A427Y525_9TREE/22-271 AC A0A427Y525.1
#=GS A0A3M7PI98_BRAPC/4-137 AC A0A3M7PI98.1
#=GS A0A0V1N2R9_9BILA/4-230 AC A0A0V1N2R9.1
#=GS A0A8H6Z8U0_9AGAR/33-252 AC A0A8H6Z8U0.1
#=GS A0A0D0DLS7_9AGAM/27-249 AC A0A0D0DLS7.1
#=GS A0A8C5F388_9SAUR/72-298 AC A0A8C5F388.1
#=GS A0A8C2VUC1_CHILA/63-289 AC A0A8C2VUC1.1
#=GS J8LN50_SACAR/11-235 AC J8LN50.1
#=GS A0A851N7R6_9GALL/63-213 AC A0A851N7R6.1
#=GS A0A5B1QF43_9AGAM/19-240 AC A0A5B1QF43.1
#=GS A0A7K8R213_9PASS/9-235 AC A0A7K8R213.1
#=GS A0A6F9B4T1_9TELE/64-171 AC A0A6F9B4T1.1
#=GS M3X3N9_FELCA/60-286 AC M3X3N9.2
#=GS A0A1M2W589_TRAPU/49-244 AC A0A1M2W589.1
#=GS A0A3Q1F4T7_9TELE/1-139 AC A0A3Q1F4T7.1
#=GS A0A8C1F436_CYPCA/7-70 AC A0A8C1F436.1
#=GS A0A3P9NHJ3_POERE/45-271 AC A0A3P9NHJ3.1
#=GS G1PSZ8_MYOLU/42-296 AC G1PSZ8.1
#=GS A0A7L4GYF8_PODST/73-299 AC A0A7L4GYF8.1
#=GS A0A0R3U2G3_MESCO/432-661 AC A0A0R3U2G3.1
#=GS A0A8C5MC24_9ANUR/101-327 AC A0A8C5MC24.1
#=GS A0A8C0C9Y0_BALMU/63-289 AC A0A8C0C9Y0.1
#=GS A0A218YTS8_9HELO/67-291 AC A0A218YTS8.1
#=GS K1PUC6_CRAGI/34-263 AC K1PUC6.1
#=GS A0A8I3Q9E3_CANLF/42-173 AC A0A8I3Q9E3.1
#=GS GTR2_SCHPO/5-229 AC O74544.1
#=GS A0A852FD99_PEUTA/10-236 AC A0A852FD99.1
#=GS A0A8B7Y6V4_ACAPL/4-230 AC A0A8B7Y6V4.1
#=GS C5LY76_PERM5/16-247 AC C5LY76.1
#=GS A0A2S7PFM4_9HELO/2-186 AC A0A2S7PFM4.1
#=GS A0A080WRI5_TRIRC/1-180 AC A0A080WRI5.1
#=GS A0A091LQP6_9GRUI/1-211 AC A0A091LQP6.1
#=GS F8Q847_SERL3/4-245 AC F8Q847.1
#=GS A0A512UC98_9ASCO/1-111 AC A0A512UC98.1
#=GS R0JU32_ANAPL/1-211 AC R0JU32.1
#=GS A0A7K7M6Z5_9PASS/73-299 AC A0A7K7M6Z5.1
#=GS V4CM50_LOTGI/38-264 AC V4CM50.1
#=GS A0A7L1K2V0_RYNNI/1-227 AC A0A7L1K2V0.1
#=GS M7SP03_EUTLA/1-223 AC M7SP03.1
#=GS A0A4X2K1X0_VOMUR/68-294 AC A0A4X2K1X0.1
#=GS A0A2Y9KSS8_ENHLU/60-286 AC A0A2Y9KSS8.1
#=GS A0A8C6H2B1_MUSSI/61-287 AC A0A8C6H2B1.1
#=GS M3X5P0_FELCA/42-268 AC M3X5P0.2
#=GS A0A7J5XS74_DISMA/45-271 AC A0A7J5XS74.1
#=GS A0A8B7TGF4_HIPAR/4-258 AC A0A8B7TGF4.1
#=GS A0A851K064_VIDCH/7-233 AC A0A851K064.1
#=GS A0A4Z2HQ02_9TELE/45-270 AC A0A4Z2HQ02.1
#=GS A0A2K5QPQ1_CEBIM/42-296 AC A0A2K5QPQ1.1
#=GS A0A507FJC7_9FUNG/11-141 AC A0A507FJC7.1
#=GS A0A8B7B979_ORYAF/42-296 AC A0A8B7B979.1
#=GS A0A5F8G582_MONDO/82-226 AC A0A5F8G582.1
#=GS A0A2K6PGU3_RHIRO/42-200 AC A0A2K6PGU3.1
#=GS B7QCU2_IXOSC/45-271 AC B7QCU2.1
#=GS A0A7M7JF68_VARDE/45-269 AC A0A7M7JF68.1
#=GS A0A8H6C884_9LECA/11-246 AC A0A8H6C884.1
#=GS A0A5C3L437_9AGAR/31-253 AC A0A5C3L437.1
#=GS A0A7N9CV57_MACFA/172-236 AC A0A7N9CV57.1
#=GS A0A8H5JMH2_9HYPO/29-269 AC A0A8H5JMH2.1
#=GS S9UJI5_9TRYP/1-197 AC S9UJI5.1
#=GS A0A8C9EUX9_PAVCR/120-242 AC A0A8C9EUX9.1
#=GS A0A8C0ESL7_BUBBB/32-258 AC A0A8C0ESL7.1
#=GS I2G059_USTH4/114-201 AC I2G059.1
#=GS A0A7L1Z233_9PASS/9-235 AC A0A7L1Z233.1
#=GS A0A7K5EFJ4_POLCE/54-280 AC A0A7K5EFJ4.1
#=GS A0A8J6AI92_GALPY/9-235 AC A0A8J6AI92.1
#=GS G8YMT5_PICSO/10-234 AC G8YMT5.1
#=GS A0A7D8V2Q0_9TREE/8-260 AC A0A7D8V2Q0.1
#=GS G4YJE6_PHYSP/33-268 AC G4YJE6.1
#=GS M3CPG3_SPHMS/1-184 AC M3CPG3.1
#=GS A0A8H7ACK1_9EURO/98-376 AC A0A8H7ACK1.1
#=GS A0A0A1NLX1_RHIZD/1-223 AC A0A0A1NLX1.1
#=GS A0A4W3IHT4_CALMI/25-251 AC A0A4W3IHT4.1
#=GS A0A0K3CBD5_RHOTO/645-873 AC A0A0K3CBD5.1
#=GS A0A165JW60_XYLHT/11-240 AC A0A165JW60.1
#=GS A0A2K5QRT2_CEBIM/60-286 AC A0A2K5QRT2.1
#=GS A0A1X7TJE0_AMPQE/61-275 AC A0A1X7TJE0.1
#=GS A0A165GI94_EXIGL/23-244 AC A0A165GI94.1
#=GS F9XIP2_ZYMTI/14-248 AC F9XIP2.1
#=GS A0A0Q3USC1_AMAAE/64-290 AC A0A0Q3USC1.1
#=GS A0A6J2MIL6_9CHIR/42-296 AC A0A6J2MIL6.1
#=GS A0A0G2H4L6_9EURO/9-238 AC A0A0G2H4L6.1
#=GS A0A1X6NAM6_9APHY/4-278 AC A0A1X6NAM6.1
#=GS A0A2T3AN67_9PEZI/1-222 AC A0A2T3AN67.1
#=GS A0A5N5NDP0_PANHP/96-322 AC A0A5N5NDP0.1
#=GS A0A1B8CXH6_9PEZI/24-253 AC A0A1B8CXH6.1
#=GS A8WT67_CAEBR/6-243 AC A8WT67.1
#=GS A0A8B7SPI9_HIPAR/9-235 AC A0A8B7SPI9.1
#=GS A0A0B2V7T4_TOXCA/5-240 AC A0A0B2V7T4.1
#=GS A0A836FEA4_9HYME/229-455 AC A0A836FEA4.1
#=GS A0A507D6E5_9FUNG/32-159 AC A0A507D6E5.1
#=GS A0A084FZ95_PSEDA/34-278 AC A0A084FZ95.1
#=GS A0A4U5VIM9_COLLU/39-265 AC A0A4U5VIM9.1
#=GS A0A7L1E6T0_OENON/15-241 AC A0A7L1E6T0.1
#=GS A0A5E8BJR6_9ASCO/20-248 AC A0A5E8BJR6.1
#=GS A0A7R8H991_LEPSM/1-214 AC A0A7R8H991.1
#=GS A0A0D1XV62_EXOME/9-238 AC A0A0D1XV62.1
#=GS A0A1S3GQV7_DIPOR/42-268 AC A0A1S3GQV7.1
#=GS A0A075AVG4_ROZAC/1-225 AC A0A075AVG4.1
#=GS W7TL06_9STRA/19-84 AC W7TL06.1
#=GS A0A6P6LQ92_CARAU/43-269 AC A0A6P6LQ92.1
#=GS A0A8D2PCF5_ZOSLA/1-223 AC A0A8D2PCF5.1
#=GS B6AJ07_CRYMR/85-315 AC B6AJ07.1
#=GS A0A673ZX39_SALTR/10-236 AC A0A673ZX39.1
#=GS A0A4P9W412_9FUNG/1-96 AC A0A4P9W412.1
#=GS A0A1G4MH95_LACFM/8-239 AC A0A1G4MH95.1
#=GS A0A814AR69_9BILA/76-300 AC A0A814AR69.1
#=GS A0A7K6WJY7_STECA/15-241 AC A0A7K6WJY7.1
#=GS G1TBT4_RABIT/51-277 AC G1TBT4.2
#=GS A0A109FIG3_9BASI/46-270 AC A0A109FIG3.1
#=GS A0A8C6EWX6_MARMA/42-296 AC A0A8C6EWX6.1
#=GS A0A668V2L9_OREAU/9-237 AC A0A668V2L9.1
#=GS A0A2K6S553_SAIBB/42-296 AC A0A2K6S553.1
#=GS W4KC54_HETIT/1-215 AC W4KC54.1
#=GS A0A167RQC8_CALVF/1-266 AC A0A167RQC8.1
#=GS A0A2T7PF46_POMCA/55-281 AC A0A2T7PF46.1
#=GS A0A507R5F4_MONPU/9-238 AC A0A507R5F4.1
#=GS A0A7K5F643_PROAR/15-241 AC A0A7K5F643.1
#=GS A0A8H6M8L3_9AGAR/20-258 AC A0A8H6M8L3.1
#=GS A0A8C2XLN5_CYCLU/45-271 AC A0A8C2XLN5.1
#=GS A0A2K5CNC8_AOTNA/66-292 AC A0A2K5CNC8.1
#=GS A0A2S4UTF1_9BASI/36-282 AC A0A2S4UTF1.1
#=GS A0A7K8QN08_9PASS/15-241 AC A0A7K8QN08.1
#=GS A0A821NQL2_9NEOP/42-268 AC A0A821NQL2.1
#=GS I1BSU4_RHIO9/1-223 AC I1BSU4.1
#=GS A0A3P6TBG0_LITSI/27-252 AC A0A3P6TBG0.1
#=GS A0A4D9DTT4_9SAUR/9-235 AC A0A4D9DTT4.1
#=GS D7FZ21_ECTSI/38-242 AC D7FZ21.1
#=GS A0A8H7CIP1_9AGAR/29-249 AC A0A8H7CIP1.1
#=GS A0A2T4GKF3_FUSCU/29-269 AC A0A2T4GKF3.1
#=GS A0A0W7W2H8_9HYPO/72-297 AC A0A0W7W2H8.1
#=GS A0A427XER5_9TREE/14-265 AC A0A427XER5.1
#=GS A0A091MXN4_9PASS/10-236 AC A0A091MXN4.1
#=GS A0A5E4BRR9_MARMO/63-289 AC A0A5E4BRR9.1
#=GS A0A8J4KD08_EUDMI/15-241 AC A0A8J4KD08.1
#=GS A0A016UHA1_9BILA/30-255 AC A0A016UHA1.1
#=GS A0A8J6JXB1_ELECQ/9-235 AC A0A8J6JXB1.1
#=GS A0A0C3S1U2_PHLGI/1-215 AC A0A0C3S1U2.1
#=GS A0A7K8J1P3_9PASS/6-232 AC A0A7K8J1P3.1
#=GS A0A1Y1V0Q4_9FUNG/1-223 AC A0A1Y1V0Q4.1
#=GS W2Y9V8_PHYPR/1-232 AC W2Y9V8.1
#=GS A0A8B9Q6H6_APTOW/9-226 AC A0A8B9Q6H6.1
#=GS A0A0K1EPU5_CHOCO/109-318 AC A0A0K1EPU5.1
#=GS A0A851UFN9_9PASS/1-211 AC A0A851UFN9.1
#=GS A0A8C4FJT8_9TELE/31-257 AC A0A8C4FJT8.1
#=GS A0A1E3IZ71_9TREE/24-259 AC A0A1E3IZ71.1
#=GS A0A1V8SAU6_9PEZI/87-311 AC A0A1V8SAU6.1
#=GS A0A8H8R3B9_9HELO/28-265 AC A0A8H8R3B9.1
#=GS A0A1Y2HXH4_9FUNG/9-245 AC A0A1Y2HXH4.1
#=GS A0A4U8URF8_STECR/5-239 AC A0A4U8URF8.1
#=GS A0A0D0E7S1_9AGAM/73-306 AC A0A0D0E7S1.1
#=GS H2PYQ4_PANTR/63-289 AC H2PYQ4.2
#=GS A0A7J8EMP0_ROUAE/1-166 AC A0A7J8EMP0.1
#=GS A0A673KIU2_9TELE/44-270 AC A0A673KIU2.1
#=GS A0A6P5BQ41_BOSIN/158-386 AC A0A6P5BQ41.1
#=GS A0A2K6UBS8_SAIBB/1-223 AC A0A2K6UBS8.1
#=GS A0A0G4M3C3_9PEZI/32-290 AC A0A0G4M3C3.1
#=GS R0IGS0_SETT2/11-242 AC R0IGS0.1
#=GS A0A835G9R4_SPOEX/41-267 AC A0A835G9R4.1
#=GS V9E680_PHYPR/1-232 AC V9E680.1
#=GS W6UDU0_ECHGR/2471-2700 AC W6UDU0.1
#=GS A0A091UCZ6_PHALP/1-227 AC A0A091UCZ6.1
#=GS A0A8C6EL39_MICMU/42-268 AC A0A8C6EL39.1
#=GS A0A7J7KIR2_BUGNE/1-120 AC A0A7J7KIR2.1
#=GS A0A7K7CFP3_APHCE/73-299 AC A0A7K7CFP3.1
#=GS A0A024UNR5_9STRA/4-230 AC A0A024UNR5.1
#=GS A0A672V053_STRHB/73-299 AC A0A672V053.1
#=GS A0A672J6D6_SALFA/62-288 AC A0A672J6D6.1
#=GS A0A4W6FJT8_LATCA/10-236 AC A0A4W6FJT8.1
#=GS A0A820CMZ7_9BILA/116-296 AC A0A820CMZ7.1
#=GS F0Y9Z6_AURAN/2-241 AC F0Y9Z6.1
#=GS A0A3M7M0U2_9PLEO/778-1009 AC A0A3M7M0U2.1
#=GS A0A452FD04_CAPHI/103-329 AC A0A452FD04.1
#=GS A0A8C9H1Q8_9PRIM/172-236 AC A0A8C9H1Q8.1
#=GS A0A7L3G9X9_9AVES/1-211 AC A0A7L3G9X9.1
#=GS X0CVJ2_FUSOX/34-259 AC X0CVJ2.1
#=GS A0A850TRH7_GRUAM/15-241 AC A0A850TRH7.1
#=GS A0A8C9PMG1_SPEDA/63-289 AC A0A8C9PMG1.1
#=GS A0A1W2TNQ1_ROSNE/29-254 AC A0A1W2TNQ1.1
#=GS A0A7J7AR80_9COLE/2-206 AC A0A7J7AR80.1
#=GS A0A8C3BUE5_CAIMO/1-139 AC A0A8C3BUE5.1
#=GS A0A7K7KMN9_9AVES/15-241 AC A0A7K7KMN9.1
#=GS A0A8C9U2S2_SERCA/1-223 AC A0A8C9U2S2.1
#=GS A0A642UZI2_DIURU/15-239 AC A0A642UZI2.1
#=GS A0A820VVH4_9BILA/27-107 AC A0A820VVH4.1
#=GS A0A5C3DZP1_9BASI/7-67 AC A0A5C3DZP1.1
#=GS A0A4Q4XCP7_9PEZI/26-265 AC A0A4Q4XCP7.1
#=GS A0A8B9P8P4_APTOW/17-172 AC A0A8B9P8P4.1
#=GS A0A0D8XR27_DICVI/30-255 AC A0A0D8XR27.1
#=GS S9W8J3_9TRYP/1-85 AC S9W8J3.1
#=GS A0A7L1MTZ8_RHICY/15-241 AC A0A7L1MTZ8.1
#=GS W5PNE1_SHEEP/1-149 AC W5PNE1.1
#=GS A0A7L2XIP9_9PASS/10-236 AC A0A7L2XIP9.1
#=GS A0A4W6BTF0_LATCA/56-282 AC A0A4W6BTF0.1
#=GS A0A3Q2D838_CYPVA/43-269 AC A0A3Q2D838.1
#=GS A0A1J9Q0M6_9EURO/9-238 AC A0A1J9Q0M6.1
#=GS A0A075A850_9TREM/129-226 AC A0A075A850.1
#=GS A0A7K7R3K7_POEAT/10-236 AC A0A7K7R3K7.1
#=GS A0A7L2APA7_9GRUI/15-241 AC A0A7L2APA7.1
#=GS D8PQJ0_SCHCM/1-223 AC D8PQJ0.1
#=GS A0A8C6T0J4_9GOBI/84-208 AC A0A8C6T0J4.1
#=GS A0A819GD27_9BILA/1-223 AC A0A819GD27.1
#=GS A0A0D7BG86_9AGAR/9-230 AC A0A0D7BG86.1
#=GS A0A8C4IHH1_DICLA/2-228 AC A0A8C4IHH1.1
#=GS A0A507DUX2_9FUNG/4-230 AC A0A507DUX2.1
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