#=GF ID HEXIM
#=GF AC PF15313.12
#=GF DE Hexamethylene bis-acetamide-inducible protein
#=GF AU Eberhardt R;0000-0001-6152-1369
#=GF AU Coggill P;0000-0001-5731-1588
#=GF AU Hetherington K;
#=GF SE Jackhmmer:Q96MH2
#=GF GA 29.00 29.00;
#=GF TC 29.00 29.50;
#=GF NC 28.80 28.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 8 -Z 90746521 -E 1000 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 12581153
#=GF RT Suppression of NF-kappaB-dependent gene expression by a
#=GF RT hexamethylene bisacetamide-inducible protein HEXIM1 in human
#=GF RT vascular smooth muscle cells.
#=GF RA Ouchida R, Kusuhara M, Shimizu N, Hisada T, Makino Y, Morimoto
#=GF RA C, Handa H, Ohsuzu F, Tanaka H;
#=GF RL Genes Cells. 2003;8:95-107.
#=GF RN [2]
#=GF RM 14580347
#=GF RT Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase
#=GF RT II transcription by the coordinated actions of HEXIM1 and 7SK
#=GF RT snRNA.
#=GF RA Yik JH, Chen R, Nishimura R, Jennings JL, Link AJ, Zhou Q;
#=GF RL Mol Cell. 2003;12:971-982.
#=GF RN [3]
#=GF RM 17724342
#=GF RT Structure of the Cyclin T binding domain of Hexim1 and molecular
#=GF RT basis for its recognition of P-TEFb.
#=GF RA Dames SA, Schonichen A, Schulte A, Barboric M, Peterlin BM,
#=GF RA Grzesiek S, Geyer M;
#=GF RL Proc Natl Acad Sci U S A. 2007;104:14312-14317.
#=GF DR INTERPRO; IPR024872;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC HEXIM is a transcriptional regulator that functions as a general
#=GF CC RNA polymerase II transcription inhibitor. In cooperation with
#=GF CC 7SK snRNA it sequesters P-TEFb in a large inactive 7SK snRNP
#=GF CC complex preventing RNA polymerase II phosphorylation and
#=GF CC subsequent transcriptional elongation. HEXIM may also regulate
#=GF CC NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional
#=GF CC activity.
#=GF SQ 1102
#=GS A0A0K0FIB9_STRVS/73-214 AC A0A0K0FIB9.1
#=GS A0A9W7WEY6_TRIRA/119-264 AC A0A9W7WEY6.1
#=GS A0A087SXW8_STEMI/191-273 AC A0A087SXW8.1
#=GS A0A7K6Y6M8_9PASE/15-152 AC A0A7K6Y6M8.1
#=GS A0A6J0J3S5_9PASS/109-246 AC A0A6J0J3S5.1
#=GS A0A3N0YQD5_ANAGA/515-668 AC A0A3N0YQD5.1
#=GS H2QD86_PANTR/102-227 AC H2QD86.1
#=GS A0A1S3GF68_DIPOR/160-297 AC A0A1S3GF68.1
#=GS A0A1U8D5V0_ALLSI/147-283 AC A0A1U8D5V0.1
#=GS A0A8W8NHL7_MAGGI/10-139 AC A0A8W8NHL7.1
#=GS A0A850YUN0_9PASS/15-152 AC A0A850YUN0.1
#=GS A0A852EBX6_VIDMA/15-152 AC A0A852EBX6.1
#=GS A0A1I7VU15_LOALO/175-260 AC A0A1I7VU15.1
#=GS A0A7K9W125_9PASS/15-152 AC A0A7K9W125.1
#=GS A0A834N9R0_VESVU/128-266 AC A0A834N9R0.1
#=GS G3REM4_GORGO/164-301 AC G3REM4.1
#=GS A0A8C7DNJ4_ONCKI/190-338 AC A0A8C7DNJ4.1
#=GS A0A8B9YKM9_BOSMU/104-229 AC A0A8B9YKM9.1
#=GS B7PYF0_IXOSC/57-199 AC B7PYF0.1
#=GS A0AAD9PG70_RIDPI/119-251 AC A0AAD9PG70.1
#=GS A0A2K6SQR5_SAIBB/102-227 AC A0A2K6SQR5.1
#=GS A0A8J5JR96_HOMAM/80-185 AC A0A8J5JR96.1
#=GS A0A7K8GWQ7_ORTSP/15-160 AC A0A7K8GWQ7.1
#=GS A0A671W1X9_SPAAU/156-304 AC A0A671W1X9.1
#=GS A0A4W2E8J3_BOBOX/47-184 AC A0A4W2E8J3.1
#=GS A0A8C5QAT7_9ANUR/100-240 AC A0A8C5QAT7.1
#=GS A0A2K5S864_CEBIM/102-227 AC A0A2K5S864.1
#=GS A0A1S3R6C4_SALSA/164-312 AC A0A1S3R6C4.1
#=GS A0A8X8BN84_POLSE/76-217 AC A0A8X8BN84.1
#=GS A0A852HWQ6_9PASS/15-152 AC A0A852HWQ6.1
#=GS A0A7K6JDU2_9CORV/15-152 AC A0A7K6JDU2.1
#=GS A0A7K6RMJ6_9AVES/26-165 AC A0A7K6RMJ6.1
#=GS A0AAQ4PG00_GASAC/156-309 AC A0AAQ4PG00.1
#=GS A0A7J8G915_ROUAE/162-299 AC A0A7J8G915.1
#=GS A0A8S1EMZ8_9PELO/39-162 AC A0A8S1EMZ8.1
#=GS A0A7J7F9V6_DICBM/164-300 AC A0A7J7F9V6.1
#=GS A0A671QFJ7_9TELE/112-262 AC A0A671QFJ7.1
#=GS A0A8C8DF74_9TELE/159-307 AC A0A8C8DF74.1
#=GS A0A060XWZ5_ONCMY/150-286 AC A0A060XWZ5.1
#=GS A0A1S3AIY9_ERIEU/159-296 AC A0A1S3AIY9.1
#=GS E2BJY2_HARSA/111-248 AC E2BJY2.1
#=GS A0A6S7G7C6_PARCT/20-146 AC A0A6S7G7C6.1
#=GS A0A7K7T6W2_9TYRA/15-152 AC A0A7K7T6W2.1
#=GS A0A3S1BKH8_ELYCH/98-234 AC A0A3S1BKH8.1
#=GS A0A7K7H373_ERIRU/15-152 AC A0A7K7H373.1
#=GS A0A8C3CNX1_CAIMO/107-163 AC A0A8C3CNX1.1
#=GS A0A7L2DJR5_CATFU/15-152 AC A0A7L2DJR5.1
#=GS A0A4Z2J8U3_9TELE/153-305 AC A0A4Z2J8U3.1
#=GS A0A158NJB7_ATTCE/114-250 AC A0A158NJB7.1
#=GS A0A2K6AM55_MACNE/164-301 AC A0A2K6AM55.1
#=GS A0AAD8AIS7_DIPPU/74-211 AC A0AAD8AIS7.1
#=GS A0AAD7RVS6_9TELE/109-256 AC A0AAD7RVS6.1
#=GS A0A8D2FKE7_THEGE/164-301 AC A0A8D2FKE7.1
#=GS A0A914VNR4_9BILA/49-160 AC A0A914VNR4.1
#=GS A0A0K0E7S8_STRER/79-214 AC A0A0K0E7S8.1
#=GS A0A7K8MTX0_9CORV/15-152 AC A0A7K8MTX0.1
#=GS A0A060XVC8_ONCMY/150-286 AC A0A060XVC8.1
#=GS A0A7L4G3G3_9COLU/23-160 AC A0A7L4G3G3.1
#=GS A0A8C3VW34_9CETA/109-234 AC A0A8C3VW34.1
#=GS A0AA39G721_MICHY/121-260 AC A0AA39G721.1
#=GS A0A814P271_ADIRI/132-268 AC A0A814P271.1
#=GS A0A9N7UH39_PLEPL/157-307 AC A0A9N7UH39.1
#=GS A0A7K9UTQ2_ANSSE/15-157 AC A0A7K9UTQ2.1
#=GS A0A8C8WY26_PANLE/164-301 AC A0A8C8WY26.1
#=GS A0A9J7IKT7_SPOLT/49-175 AC A0A9J7IKT7.1
#=GS A0A8K1GDY4_9PASS/109-246 AC A0A8K1GDY4.1
#=GS A0A851KXQ4_VIDCH/15-152 AC A0A851KXQ4.1
#=GS A0A0J7L2V3_LASNI/69-205 AC A0A0J7L2V3.1
#=GS A0A8B6D8D1_MYTGA/79-220 AC A0A8B6D8D1.1
#=GS F7I988_CALJA/102-227 AC F7I988.2
#=GS A0AAD9QP96_ACRCE/96-239 AC A0AAD9QP96.1
#=GS HEXI1_RAT/161-298 AC Q5M9G1.1
#=GS A0A672QIA6_SINGR/114-262 AC A0A672QIA6.1
#=GS A0A818C886_9BILA/128-266 AC A0A818C886.1
#=GS A0A921ZWP2_MANSE/52-177 AC A0A921ZWP2.1
#=GS B3LW21_DROAN/75-171 AC B3LW21.1
#=GS A0A7K4YFY4_BUCAB/1-47 AC A0A7K4YFY4.1
#=GS A0AAY4CMR0_9TELE/63-201 AC A0AAY4CMR0.1
#=GS F1RR20_PIG/54-179 AC F1RR20.2
#=GS A0A7L2SMJ0_9PASS/15-152 AC A0A7L2SMJ0.1
#=GS A0A212DB93_CEREH/125-262 AC A0A212DB93.1
#=GS A0A7K4Q3C8_MELMO/15-152 AC A0A7K4Q3C8.1
#=GS A0AAE1K897_PETCI/47-172 AC A0AAE1K897.1
#=GS A0A2R8ZEF1_PANPA/164-301 AC A0A2R8ZEF1.1
#=GS A0A7K6UXN0_9PASS/15-152 AC A0A7K6UXN0.1
#=GS A0A3Q0E1B0_CARSF/173-298 AC A0A3Q0E1B0.1
#=GS A0A096P656_PAPAN/102-227 AC A0A096P656.2
#=GS A0A7M7GR05_STRPU/112-229 AC A0A7M7GR05.1
#=GS A0A7K6A881_ONYCO/23-160 AC A0A7K6A881.1
#=GS A0A5N3X3F0_MUNRE/125-262 AC A0A5N3X3F0.1
#=GS A0A667Z9R2_9TELE/163-317 AC A0A667Z9R2.1
#=GS A0AAE1DBJ1_9GAST/99-232 AC A0AAE1DBJ1.1
#=GS A0A7K7LHJ2_9AVES/23-160 AC A0A7K7LHJ2.1
#=GS A0A811XSL2_NYCPR/164-301 AC A0A811XSL2.1
#=GS A0A2G9U0U1_TELCI/44-181 AC A0A2G9U0U1.1
#=GS A0A3L8RYZ4_CHLGU/108-245 AC A0A3L8RYZ4.1
#=GS A0A7K9YVG8_9GALL/23-160 AC A0A7K9YVG8.1
#=GS B7Q0M5_IXOSC/88-216 AC B7Q0M5.1
#=GS A0A833WGA1_9HYME/127-264 AC A0A833WGA1.1
#=GS A0A443RZP4_9ACAR/118-231 AC A0A443RZP4.1
#=GS A0A8J2PV77_9HEXA/162-297 AC A0A8J2PV77.1
#=GS A0A1D1UT48_RAMVA/144-262 AC A0A1D1UT48.1
#=GS A0A553NVE9_TIGCA/159-275 AC A0A553NVE9.1
#=GS A0A7L1ZM39_LEILU/15-152 AC A0A7L1ZM39.1
#=GS A0A8C5YPH5_MARMA/161-298 AC A0A8C5YPH5.1
#=GS A0A7J8CYM6_MOLMO/85-211 AC A0A7J8CYM6.1
#=GS Q9U2K4_CAEEL/38-190 AC Q9U2K4.1
#=GS A0A8X6LH87_TRICU/74-210 AC A0A8X6LH87.1
#=GS A0A7K9R9N5_IRECY/15-152 AC A0A7K9R9N5.1
#=GS A0A1L8EL14_XENLA/84-228 AC A0A1L8EL14.1
#=GS A0A813Z6M4_ADIRI/125-261 AC A0A813Z6M4.1
#=GS A0A7L0NLQ2_9PASS/23-160 AC A0A7L0NLQ2.1
#=GS A0A9Q1J3I9_SYNKA/107-253 AC A0A9Q1J3I9.1
#=GS A0A7L2J4N1_CINMU/15-152 AC A0A7L2J4N1.1
#=GS A0A9P0JQL5_ACAOB/47-179 AC A0A9P0JQL5.1
#=GS A0A091D4V1_FUKDA/312-387 AC A0A091D4V1.1
#=GS A0A8C0K9T1_CANLU/164-301 AC A0A8C0K9T1.1
#=GS A0A7K5KQL7_VIRAL/15-152 AC A0A7K5KQL7.1
#=GS A0A4U5N2T7_STECR/28-118 AC A0A4U5N2T7.1
#=GS A0A2K5KTE5_CERAT/164-301 AC A0A2K5KTE5.1
#=GS A0A669Q055_PHACC/94-231 AC A0A669Q055.1
#=GS A0A852INB8_9PICI/15-152 AC A0A852INB8.1
#=GS A0A1I7VU57_LOALO/8-82 AC A0A1I7VU57.1
#=GS A0A7J7IYF8_BUGNE/243-352 AC A0A7J7IYF8.1
#=GS A0A8C9HMA3_9PRIM/164-301 AC A0A8C9HMA3.1
#=GS A0A9B0GW95_ODORO/119-191 AC A0A9B0GW95.1
#=GS A0A016SYP4_9BILA/1-108 AC A0A016SYP4.1
#=GS A0A5G2RFM4_PIG/152-289 AC A0A5G2RFM4.1
#=GS A0A556TIQ7_BAGYA/542-693 AC A0A556TIQ7.1
#=GS A0A2K6EM81_PROCO/102-227 AC A0A2K6EM81.1
#=GS A0A368GYM5_ANCCA/43-180 AC A0A368GYM5.1
#=GS A0A6I9IS67_VICPA/165-302 AC A0A6I9IS67.1
#=GS A0A9P0NLI1_9DIPT/100-219 AC A0A9P0NLI1.1
#=GS A0A9P0NHQ1_APHGO/87-219 AC A0A9P0NHQ1.1
#=GS A0A2J8UYU4_PONAB/164-301 AC A0A2J8UYU4.1
#=GS A0A2A3EQY8_APICC/129-266 AC A0A2A3EQY8.1
#=GS A0A3Q7NB86_CALUR/214-336 AC A0A3Q7NB86.1
#=GS A0A0V0SMM1_9BILA/94-248 AC A0A0V0SMM1.1
#=GS A0A7L1F528_SYLBO/15-139 AC A0A7L1F528.1
#=GS A0AA36D130_9BILA/40-168 AC A0AA36D130.1
#=GS A0A6P9A5C8_THRPL/90-193 AC A0A6P9A5C8.1
#=GS A0A2A2LE49_9BILA/56-203 AC A0A2A2LE49.1
#=GS W5NLV7_LEPOC/119-265 AC W5NLV7.1
#=GS A0A9W3GBN3_CAMBA/96-221 AC A0A9W3GBN3.1
#=GS A0A7K7CLH6_APHCE/15-152 AC A0A7K7CLH6.1
#=GS A0A8C8AX08_9STRI/61-198 AC A0A8C8AX08.1
#=GS A0A3R7PDW1_PENVA/76-180 AC A0A3R7PDW1.1
#=GS A0A6H5HHT7_9HEMI/36-173 AC A0A6H5HHT7.1
#=GS A0A2K6BXK4_MACNE/155-280 AC A0A2K6BXK4.1
#=GS A0A7L0YHH3_9PASE/1-47 AC A0A7L0YHH3.1
#=GS A0A7K5IAL2_CROSL/15-151 AC A0A7K5IAL2.1
#=GS A0A852PDG4_9PASS/15-152 AC A0A852PDG4.1
#=GS A0A9J6BVS8_POLVA/93-206 AC A0A9J6BVS8.1
#=GS A0A8W8LMC9_MAGGI/86-233 AC A0A8W8LMC9.1
#=GS A0A7L1PW93_ORIOR/15-138 AC A0A7L1PW93.1
#=GS A0A151JS31_9HYME/114-250 AC A0A151JS31.1
#=GS A0A6J2FX99_9PASS/109-246 AC A0A6J2FX99.1
#=GS A0A5C6NSJ0_9TELE/156-308 AC A0A5C6NSJ0.1
#=GS A0A673W2U4_SALTR/164-312 AC A0A673W2U4.1
#=GS A0A9B0GW95_ODORO/182-239 AC A0A9B0GW95.1
#=GS A0A383ZYU5_BALAS/336-461 AC A0A383ZYU5.1
#=GS A0A3B1IEN4_ASTMX/240-297 AC A0A3B1IEN4.1
#=GS A0A8C3W426_9CETA/152-289 AC A0A8C3W426.1
#=GS A0A484BHA2_DRONA/93-149 AC A0A484BHA2.1
#=GS A0A218UFY8_9PASE/108-245 AC A0A218UFY8.1
#=GS A0A7L2VFI2_9AVES/15-152 AC A0A7L2VFI2.1
#=GS A0A7L2ISI1_9PICI/1-142 AC A0A7L2ISI1.1
#=GS A0A1U8D2F0_MESAU/157-294 AC A0A1U8D2F0.1
#=GS A0A8B9YIG7_BOSMU/47-184 AC A0A8B9YIG7.1
#=GS A0A8B7NT09_HYAAZ/196-318 AC A0A8B7NT09.1
#=GS A0A6P6BQC3_PTEVA/162-299 AC A0A6P6BQC3.1
#=GS A0A6J3H7R6_SAPAP/124-249 AC A0A6J3H7R6.1
#=GS A0AAJ7JFD7_9HYME/125-262 AC A0AAJ7JFD7.1
#=GS A0A5N3X3A8_MUNRE/128-243 AC A0A5N3X3A8.1
#=GS F7DSW2_HORSE/164-301 AC F7DSW2.1
#=GS A0A6P7IJY1_9TELE/146-295 AC A0A6P7IJY1.1
#=GS A0A8J6KWA8_MICOH/161-298 AC A0A8J6KWA8.1
#=GS A0A8B7PHM0_HYAAZ/54-237 AC A0A8B7PHM0.1
#=GS A0A6P7N5Y4_BETSP/165-314 AC A0A6P7N5Y4.1
#=GS A0AAJ7HM85_RHIBE/102-227 AC A0AAJ7HM85.1
#=GS H3A262_LATCH/78-138 AC H3A262.1
#=GS A0A8C7E2D4_NAJNA/115-208 AC A0A8C7E2D4.1
#=GS A6HJQ2_RAT/101-226 AC A6HJQ2.1
#=GS A0A9P9Z0V8_9MUSC/61-164 AC A0A9P9Z0V8.1
#=GS A0A7K4X3N6_REGSA/8-145 AC A0A7K4X3N6.1
#=GS A0A6I9KT15_PERMB/159-296 AC A0A6I9KT15.1
#=GS A0A0R3PQV4_ANGCS/43-166 AC A0A0R3PQV4.1
#=GS A0A5A9PU89_9TELE/119-264 AC A0A5A9PU89.1
#=GS A0A7L2BQW8_9PASS/15-152 AC A0A7L2BQW8.1
#=GS A7RUX8_NEMVE/91-221 AC A7RUX8.1
#=GS A0A6J8BA57_MYTCO/73-216 AC A0A6J8BA57.1
#=GS A0A3P8RTF9_AMPPE/158-304 AC A0A3P8RTF9.1
#=GS A0A8S3ZT42_9EUPU/98-234 AC A0A8S3ZT42.1
#=GS K7ERG7_HUMAN/124-203 AC K7ERG7.8
#=GS A0A7J7U815_PIPKU/85-210 AC A0A7J7U815.1
#=GS A0A8B8B0A0_CRAVI/97-226 AC A0A8B8B0A0.1
#=GS A0A7L3BM70_PELUR/18-155 AC A0A7L3BM70.1
#=GS A0A3Q4I8J9_NEOBR/155-304 AC A0A3Q4I8J9.1
#=GS G3WBU7_SARHA/54-182 AC G3WBU7.2
#=GS A0A7L2G4Q3_NYCGR/15-152 AC A0A7L2G4Q3.1
#=GS M4A1U7_XIPMA/160-310 AC M4A1U7.2
#=GS A0A9Q0MIM8_BLOTA/271-432 AC A0A9Q0MIM8.1
#=GS G1KSF4_ANOCA/144-278 AC G1KSF4.3
#=GS A0A7K9NB40_9CORV/1-135 AC A0A7K9NB40.1
#=GS A0AAD9J424_9ANNE/91-232 AC A0AAD9J424.1
#=GS A0A2K5ZKW1_MANLE/102-227 AC A0A2K5ZKW1.1
#=GS A0A851J2L0_9PASS/15-152 AC A0A851J2L0.1
#=GS A0A8X6MDW3_NEPPI/75-210 AC A0A8X6MDW3.1
#=GS A0A6J0DB66_PERMB/101-226 AC A0A6J0DB66.1
#=GS A0A852FJZ5_PEUTA/15-152 AC A0A852FJZ5.1
#=GS HEXI1_MOUSE/161-298 AC Q8R409.1
#=GS A0A0V0VXG0_9BILA/94-247 AC A0A0V0VXG0.1
#=GS F7E876_MONDO/159-296 AC F7E876.2
#=GS A0A8R1WGY0_BOMMO/51-177 AC A0A8R1WGY0.1
#=GS A0A7L2P8U1_PYCJO/15-152 AC A0A7L2P8U1.1
#=GS A0A8T0EYB7_ARGBR/82-217 AC A0A8T0EYB7.1
#=GS A0A6J1YIH3_ACIJB/164-301 AC A0A6J1YIH3.1
#=GS G0N660_CAEBE/39-206 AC G0N660.1
#=GS A0AAE1NMD3_9EUCA/77-185 AC A0AAE1NMD3.1
#=GS A0A8C7C1E4_NEOVI/164-301 AC A0A8C7C1E4.1
#=GS A0A8C6IWA0_MELUD/109-246 AC A0A8C6IWA0.2
#=GS A0A7K9J791_9CORV/15-152 AC A0A7K9J791.1
#=GS A0A914BL06_PATMI/150-266 AC A0A914BL06.1
#=GS A0A803YK87_MELGA/242-379 AC A0A803YK87.1
#=GS A0A6P6XN85_DERPT/109-264 AC A0A6P6XN85.1
#=GS A0A8C9KR74_PANTA/102-227 AC A0A8C9KR74.1
#=GS A0A7K5SGZ1_9FRIN/15-152 AC A0A7K5SGZ1.1
#=GS A0A7K9HR50_9PICI/15-152 AC A0A7K9HR50.1
#=GS A0A8N5F1Y5_GEOFO/1-57 AC A0A8N5F1Y5.1
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A0AAD8CXT8_ACIOX/137-262 ........................................................WKPY...FKLSWEEKKEL.DER.E..T..A....R.A..S..R....V.REE.....M...F.........A.K..G.....LPVAPYNTTQFLMEEH.DR.E........EPD..LK...T...ELG...........................................A..RR.P..A...G.....V-S...RSE.D.....................TA.SEE.E..S...V---..----.......................--.----............--EPE....E.F...LQRDFSETYE...........KYH...AESLQSKSKQELVREYLELEKCLSRL.......................................
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A0A7K5ICY4_TOXRE/15-153 ........................................................WKPY...SKLSWEEKQQF.DER.Q..S..L....R.A..S..R....L.RAE.....M...F.........A.K..G.....QPVAPYNTTQFLMEDH.DQ.E........EPD..LK...T...GLY...........................................P..RR.-..-...-.....AAA...KS-.D.....................DT.SEE.D..F...LDDA..ADED.......................GG.SDGM...........gGGDGS....E.F...LQRDFSETYE...........RYH...VESLQNMSKQELVKEYLELEKCLSRM.......................................
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A0A7K7R443_POEAT/15-152 ........................................................WKPY...SKLSWEEKQQF.DER.Q..S..L....R.A..S..R....L.RAE.....M...F.........A.K..G.....QPVAPYNTTQFLMEDH.DQ.E........EPD..LK...T...GLY...........................................P..RR.-..-...-.....AAA...KS-.D.....................DT.SEE.D..F...LDDA..ADED.......................GG.SDGM............GGDGS....E.F...LQRDFSETYE...........RYH...VESLQNMSKQELVKEYLELEKCLSRM.......................................
A0A9N9R456_9NEOP/50-176 .......................................................m-KPF...LKVPWQDRRKY.DK-.-..P..K....R.N..N..R....F.RKI.....V...V.........A.K..T.....R--APFNNNQFLMEIH.K-.P........EPE..NN...F...HLA...........................................Q..TP.S..A...R.....TRD...SSF.S.....................ID.SED.N..Y...FFSL..PEDE.......................--.----............----E....E.Y...LTKEFSSVYE...........DAQ...TERLSNMSKNELIQEYLILEAKYDSL.......................................
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A0A7L0LFY4_9SYLV/15-152 ........................................................WKPY...SKLSWEEKQQF.DER.Q..S..L....R.A..S..R....L.RAE.....M...F.........A.K..G.....QPVAPYNTTQFLMEDH.DQ.E........EPD..LK...T...GLY...........................................P..RR.-..-...-.....AAA...KS-.D.....................DT.SEE.D..F...LDDG..ADED.......................GG.SDGM............GGDGS....E.F...LQRDFSETYE...........RYH...VESLQNMSKQELVKEYLELEKCLSRM.......................................
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A0AA88P9A4_9TELE/113-260 ........................................................WKPY...FKLTWEEKKEL.DER.E..T..A....R.A..S..R....V.RAE.....M...F.........A.K..G.....LPVAPYNTTQFLMEEH.DR.E........EPD..LN...T...ELG...........................................G..RK.-..S...-.....GAI...RSD.D.....................TA.SED.E..N...FEGE..DEDEee..................rggEG.SDGMg.........rpGHAGG....E.F...LQRDFSETYE...........RYH...VETLQNMSKQELVREYLELEKCMSRL.......................................
A0A7I8W2D0_9ANNE/28-141 .................................rkqkggahhskkwrpylkntens----...-----------.---.-..-..-....-.-..-..-....V.EK-.....-...K.........D.N..G....fQATAPSNTTQFLIDQH.GA.T........TPD..FD...-...---...........................................-..--.-..-...-.....KSS...DEE.D.....................TS.L--.-..-...----..-EED.......................--.----............IRVNP....D.F...LTKEFSQEYR...........SYQ...VERLYSLTKEELVRECLSLESKFDK-t......................................
A0A6I9MYX0_9TELE/161-310 ........................................................WKPY...YKLNWDERKAL.EEK.E..T..A....R.A..S..R....L.REE.....M...F.........A.K..G.....LPVAPYNTTQFLMDEH.DR.E........EPD..LN...T...ETG...........................................V..RR.T..S...G.....VGT...RME.D.....................TG.SEE.D..L...FDNE..EEDEdd..................gsgGG.SDGIg.........rpGNAGG....E.F...LQRDFSETYE...........MYH...VESLQNMTKQELVQEYLELEKCMSRL.......................................
A0A6P8ELZ7_CLUHA/127-274 ........................................................WKPY...YKLSWEEKKEL.DER.E..T..I....R.A..S..R....V.REE.....M...F.........A.K..G.....LPVAPYNTTQFLMDEH.DR.E........EPD..LN...T...ELG...........................................G..RR.S..F...G.....-AN...RSE.D.....................TA.SEE.D..C...IEQD..EEEDee...................gdGG.SDGMg.........rpGQAGG....E.F...LQKDFSETYE...........RYH...VETLQNMSKQELVQEYLELEKCMSRL.......................................
A0A8X6JAG0_TRICU/77-132 ........................................................FKSY...YELTREEKEKI.DKR.N..L..R....Q.R..R..R....R.RVK.....L...R.........K.S..G.....MPLAPLNTTQFIVNDK.K-.-........---..--...-...---...........................................-..--.-..-...-.....---...---.-.....................--.---.-..-...----..----.......................--.----............-----....-.-...----------...........---...--------------------------cvdiy..................................
A0A8T0BDL3_SILME/140-291 ........................................................WKPY...FKLTWEEKKEL.DER.E..S..A....R.A..S..R....V.RAE.....M...F.........A.K..G.....LPVAPYNTTQFLMEEH.DR.E........EPD..LN...T...ERC...........................................N..RR.S..F...G.....-AN...RSE.D.....................TA.SEE.D..C...FEPD..DEEEeegd...............gaegGE.SDGMg.........raAGAGG....E.F...LQRDFSETYE...........RYH...VETLQNMSKQELVREYLELEKSMSRL.......................................
A0AAD9EUK2_DISEL/159-308 ........................................................WKPY...YKLNWDERKAL.EEK.E..T..A....R.A..S..R....L.REE.....M...F.........A.K..G.....LPVAPYNTTQFLMDEH.DR.E........EPD..LN...T...ETG...........................................V..RR.T..S...G.....VGT...RME.D.....................TG.SEE.D..L...FDNE..EEDEdd..................gsgGG.SDGIg.........rpGNAGG....E.F...LQRDFSETYE...........MYH...VESLQNMTKQELVQEYLELEKCMSRL.......................................
#=GC seq_cons ........................................................W+PY....cLoWpEKpph.DE+.p..o..h....R.A..S..R....l.RtE.....M...F.........A.K..G.....pPVAPYNTTQFLM-DH.Dp.E........EPD..Lc...s...thh...........................................s..p+..............sss...cS..s.....................ss.S--.c..h...hppt..t---.......................us.SDuh............Gtstu....E.F...LQRDFSEsYE...........+YH...sESLQsMSKQELl+EYL-LE+plSph.......................................
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