LinkDB: HTH_3
Original site: HTH_3
Gene (217356) KEGG GENES (217356) Protein sequence (397556) UniProt (397363) SWISS-PROT (193) 3D Structure (78) PDB (77) SCOP (1) Protein domain (4) InterPro (1) Pfam (2) NCBI-CDD (1) Literature (1) PubMed (1) All databases (614995)
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#=GF ID HTH_3 #=GF AC PF01381.25 #=GF DE Helix-turn-helix #=GF AU Bateman A;0000-0002-6982-4660 #=GF SE SCOP #=GF GA 23.00 23.00; #=GF TC 23.00 23.00; #=GF NC 22.90 22.90; #=GF BM hmmbuild HMM.ann SEED.ann #=GF SM hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq #=GF TP Domain #=GF WK Helix-turn-helix #=GF CL CL0123 #=GF RN [1] #=GF RM 20196080 #=GF RT The crystal structure of NGO0477 from Neisseria gonorrhoeae #=GF RT reveals a novel protein fold incorporating a helix-turn-helix #=GF RT motif. #=GF RA Ren J, Sainsbury S, Nettleship JE, Saunders NJ, Owens RJ; #=GF RL Proteins. 2010;78:1798-1802. #=GF DR INTERPRO; IPR001387; #=GF DR SCOP; 1r69; fa; #=GF DR HOMSTRAD; rep; #=GF DR SO; 0000417; polypeptide_domain; #=GF CC This large family of DNA binding helix-turn helix proteins #=GF CC includes Cro Swiss:P03036 and CI Swiss:P03034. Within the #=GF CC protein Swiss:Q5F9C2, the full protein fold incorporates a #=GF CC helix-turn-helix motif, but the function of this member is #=GF CC unlikely to be that of a DNA-binding regulator, the function of #=GF CC most other members, so is not necessarily characteristic of the #=GF CC whole family [1]. #=GF SQ 85562 #=GS A0A089KLW3_9BACL/10-64 AC A0A089KLW3.1 #=GS A0A3N4U2Z8_9ACTN/14-68 AC A0A3N4U2Z8.1 #=GS F4LS91_TEPAE/12-66 AC F4LS91.1 #=GS F5A3H2_9CAUD/3-57 AC F5A3H2.1 #=GS A0A0K8P453_IDESA/48-102 AC A0A0K8P453.1 #=GS A0A1H2PZ60_9BACL/13-65 AC A0A1H2PZ60.1 #=GS A0A2V4P104_9ACTN/28-66 AC A0A2V4P104.1 #=GS A0A2U1CHK9_9BURK/22-75 AC A0A2U1CHK9.1 #=GS A0A3Q9WIA6_9MICC/20-74 AC A0A3Q9WIA6.1 #=GS A0A1X1D8T7_9GAMM/14-68 AC A0A1X1D8T7.1 #=GS D6GQS3_FILAD/7-61 AC D6GQS3.2 #=GS A0A387BFW6_9LACT/7-61 AC A0A387BFW6.1 #=GS A0A1I6JQ48_9BURK/11-65 AC A0A1I6JQ48.1 #=GS A0A174HN97_9FIRM/17-71 AC A0A174HN97.1 #=GS U6F3T0_LACHE/7-52 AC U6F3T0.1 #=GS A0A0A0MBZ7_9GAMM/14-69 AC A0A0A0MBZ7.1 #=GS Q9KCX6_BACHD/6-60 AC Q9KCX6.1 #=GS A0A098EH71_9BACL/8-62 AC A0A098EH71.1 #=GS A0A084A5A4_9GAMM/35-81 AC A0A084A5A4.1 #=GS A0A2U0HRL0_9FLAO/38-91 AC A0A2U0HRL0.1 #=GS A0A6G2W0H5_9ACTN/22-69 AC A0A6G2W0H5.1 #=GS A0A372EV59_9RHOB/8-62 AC A0A372EV59.1 #=GS G7Z8C4_AZOL4/11-65 AC G7Z8C4.1 #=GS A0A291M4A0_9RHOB/19-73 AC A0A291M4A0.1 #=GS A0A3E2NDJ3_9CLOT/7-61 AC A0A3E2NDJ3.1 #=GS A0A172YB05_9GAMM/12-61 AC A0A172YB05.1 #=GS A0A2Z2NZB3_9GAMM/16-70 AC A0A2Z2NZB3.1 #=GS R6E094_9FIRM/7-62 AC R6E094.1 #=GS A0A369Q8V3_9BACT/103-156 AC A0A369Q8V3.1 #=GS A0A1H6JST9_9FLAO/8-62 AC A0A1H6JST9.1 #=GS A0A2T0RH43_9RHOB/6-62 AC A0A2T0RH43.1 #=GS A0A096BJS0_9CLOT/8-62 AC A0A096BJS0.1 #=GS A0A4Q1RPL2_9ACTN/13-67 AC A0A4Q1RPL2.1 #=GS A0A327Y525_RHIET/4-50 AC A0A327Y525.1 #=GS A0A417C9A2_9FIRM/9-63 AC A0A417C9A2.1 #=GS A0A1G8ZKU7_9ACTN/14-68 AC A0A1G8ZKU7.1 #=GS A0A063Y3Y3_9GAMM/14-68 AC A0A063Y3Y3.1 #=GS A0A4R0NCZ9_9SPHI/8-62 AC A0A4R0NCZ9.1 #=GS K6W9R2_9ACTN/14-68 AC K6W9R2.1 #=GS A0A0A3IJ31_9BACI/6-60 AC A0A0A3IJ31.1 #=GS C0D412_9FIRM/24-78 AC C0D412.1 #=GS R5UYQ9_9FIRM/6-60 AC R5UYQ9.1 #=GS A0A4V5V081_9ACTN/1-38 AC A0A4V5V081.1 #=GS K9W5E6_9CYAN/20-75 AC K9W5E6.1 #=GS A0A1S1RB59_9ACTN/12-66 AC A0A1S1RB59.1 #=GS A0A1L8QS28_9ENTE/7-61 AC A0A1L8QS28.1 #=GS A0A366DMG8_9BACI/12-62 AC A0A366DMG8.1 #=GS A0A2V5LLN3_9MICC/44-97 AC A0A2V5LLN3.1 #=GS A0A126V1Y6_9RHOB/23-77 AC A0A126V1Y6.1 #=GS A0A388TJ46_9BACT/11-65 AC A0A388TJ46.1 #=GS A0A1S2QHB9_9BACI/14-68 AC A0A1S2QHB9.1 #=GS A0A1I5MDG8_9PSEU/14-68 AC A0A1I5MDG8.1 #=GS T0S5I9_LACLC/7-61 AC T0S5I9.1 #=GS J2KXK1_9RHIZ/14-68 AC J2KXK1.1 #=GS A0A1X1T2L4_9MYCO/10-64 AC A0A1X1T2L4.1 #=GS A0A2V4BQ66_9PSEU/15-69 AC A0A2V4BQ66.1 #=GS A0A1V3ND57_9GAMM/13-68 AC A0A1V3ND57.1 #=GS U2DCV8_9FIRM/21-75 AC U2DCV8.1 #=GS A0A4Y7RBG7_9FIRM/37-89 AC A0A4Y7RBG7.1 #=GS A0A061P433_9BACL/11-65 AC A0A061P433.1 #=GS E7FXA8_ERYRH/1-46 AC E7FXA8.1 #=GS D4E794_SEROD/12-66 AC D4E794.1 #=GS A0A4D6HF24_9EURY/102-155 AC A0A4D6HF24.1 #=GS A0A366WPY5_9ALTE/13-67 AC A0A366WPY5.1 #=GS A0A1I5ZGQ8_9RHOB/12-64 AC A0A1I5ZGQ8.1 #=GS A0A1H2PRU1_9BURK/17-62 AC A0A1H2PRU1.1 #=GS A0A1S5S7W3_9CAUD/14-68 AC A0A1S5S7W3.1 #=GS A0A1G6IDK2_9BACT/7-61 AC A0A1G6IDK2.1 #=GS A0A417NGB5_9FIRM/8-62 AC A0A417NGB5.1 #=GS V2YGN7_9FIRM/10-64 AC V2YGN7.1 #=GS A0A2P7P8B8_9GAMM/9-63 AC A0A2P7P8B8.1 #=GS A0A3S2TLX0_9BURK/19-73 AC A0A3S2TLX0.1 #=GS A0A1C0BXD1_9FIRM/7-61 AC A0A1C0BXD1.1 #=GS A0A2N1DFZ0_9ALTE/6-60 AC A0A2N1DFZ0.1 #=GS A0A172JIF5_9CAUD/76-118 AC A0A172JIF5.1 #=GS A0A498B5D2_9ACTN/26-99 AC A0A498B5D2.1 #=GS A0A0P8YTA0_9RHOB/11-65 AC A0A0P8YTA0.1 #=GS A0A2K8PPY0_STRLA/24-78 AC A0A2K8PPY0.1 #=GS Q2GFI4_EHRCR/6-61 AC Q2GFI4.1 #=GS A0A2I7SCH9_9CAUD/5-59 AC A0A2I7SCH9.1 #=GS B0JR11_MICAN/33-85 AC B0JR11.1 #=GS H8FUS3_MAGML/7-56 AC H8FUS3.1 #=GS K2LSH9_9RHIZ/36-88 AC K2LSH9.1 #=GS K9X7H7_9NOST/8-63 AC K9X7H7.1 #=GS A0A0M2UYY2_9BACT/13-67 AC A0A0M2UYY2.1 #=GS D9RUX7_PREMB/10-63 AC D9RUX7.1 #=GS A0A1H3II00_9RHOB/50-104 AC A0A1H3II00.1 #=GS R5L7P6_9FIRM/18-77 AC R5L7P6.1 #=GS A0A0F4NYP4_PSEO7/9-67 AC A0A0F4NYP4.1 #=GS A0A3A8YV88_9BACT/7-61 AC A0A3A8YV88.1 #=GS A0A3A5FC45_9DELT/14-67 AC A0A3A5FC45.1 #=GS D1PM01_9FIRM/5-59 AC D1PM01.1 #=GS F5YYT7_MYCSD/1-46 AC F5YYT7.1 #=GS A0A1M6JHC5_9FIRM/7-61 AC A0A1M6JHC5.1 #=GS A0A3S3RDP9_9RHIZ/14-68 AC A0A3S3RDP9.1 #=GS A0A0Q8B005_9RHIZ/14-69 AC A0A0Q8B005.1 #=GS A0A494YZY8_9BACI/6-61 AC A0A494YZY8.1 #=GS A0A066WXI2_COLSU/86-142 AC A0A066WXI2.1 #=GS A0A1S1NX49_9GAMM/19-71 AC A0A1S1NX49.1 #=GS A0A1I1MYE8_9FIRM/9-63 AC A0A1I1MYE8.1 #=GS A0A239ALH0_9FIRM/8-63 AC A0A239ALH0.1 #=GS A0A3T0N2L3_9RHOB/10-65 AC A0A3T0N2L3.1 #=GS A0A3P1VNW8_9MICO/5-59 AC A0A3P1VNW8.1 #=GS A0A3S1D198_9BACT/8-62 AC A0A3S1D198.1 #=GS A0A1I6D4T9_9FIRM/6-60 AC A0A1I6D4T9.1 #=GS A0A0F7K278_9GAMM/16-69 AC A0A0F7K278.1 #=GS A0A1N6S1H5_9BACI/7-62 AC A0A1N6S1H5.1 #=GS A0A069RI30_PEPLI/10-64 AC A0A069RI30.1 #=GS C6RI39_9PROT/24-81 AC C6RI39.1 #=GS A5N4A3_CLOK5/5-59 AC A5N4A3.1 #=GS A0A3A9CYU0_9BACT/6-60 AC A0A3A9CYU0.1 #=GS A0A1Y4NK50_9FIRM/19-73 AC A0A1Y4NK50.1 #=GS R6BXZ4_9CLOT/3-60 AC R6BXZ4.1 #=GS R5U3Z5_9FIRM/34-84 AC R5U3Z5.1 #=GS A0A316J5Z5_9RHIZ/34-88 AC A0A316J5Z5.1 #=GS A0A0J8VLN8_9ENTR/8-62 AC A0A0J8VLN8.1 #=GS A0A429Z1Z8_9RHIZ/16-70 AC A0A429Z1Z8.1 #=GS A0A0C1LDT5_9BACT/8-62 AC A0A0C1LDT5.1 #=GS A0A1M5SBR5_9FIRM/8-62 AC A0A1M5SBR5.1 #=GS W0EG17_9FIRM/6-60 AC W0EG17.1 #=GS A0A385Z7P3_9PSED/7-61 AC A0A385Z7P3.1 #=GS A0A6M1UM79_9BACT/8-61 AC A0A6M1UM79.1 #=GS A0A101UIH1_9ACTN/13-69 AC A0A101UIH1.1 #=GS R7FPM3_9CLOT/9-64 AC R7FPM3.1 #=GS A0A0U4FVG1_9MICO/22-74 AC A0A0U4FVG1.1 #=GS B5E8H8_GEOBB/6-59 AC B5E8H8.1 #=GS A0A2U2CEB9_9RHOB/17-71 AC A0A2U2CEB9.1 #=GS A0A514CXB9_9CAUD/15-69 AC A0A514CXB9.1 #=GS C0ECB2_9FIRM/18-74 AC C0ECB2.1 #=GS A0A1P8UWC6_9RHOB/19-73 AC A0A1P8UWC6.1 #=GS A0A1I6KMP1_9BURK/18-66 AC A0A1I6KMP1.1 #=GS A0A1I5BRE4_9FIRM/311-363 AC A0A1I5BRE4.1 #=GS A0A373N9V1_9FIRM/19-73 AC A0A373N9V1.1 #=GS C0EAV4_9FIRM/9-63 AC C0EAV4.1 #=GS A0A3P1SGV0_9ACTO/15-69 AC A0A3P1SGV0.1 #=GS R7A3T6_9FIRM/9-63 AC R7A3T6.1 #=GS A0A3E2YSJ8_9ACTN/32-86 AC A0A3E2YSJ8.1 #=GS G5IKW6_9CLOT/14-63 AC G5IKW6.1 #=GS A0A519PSZ8_9BACT/5-60 AC A0A519PSZ8.1 #=GS R5HHL3_9SPIR/14-69 AC R5HHL3.1 #=GS W9UYE8_9GAMM/51-97 AC W9UYE8.1 #=GS C4Z3T7_LACE2/35-91 AC C4Z3T7.1 #=GS A0A556M9N6_9SPHI/19-73 AC A0A556M9N6.1 #=GS A0A2G9DGG8_9ACTN/31-84 AC A0A2G9DGG8.1 #=GS A0A1Q5KY65_9ACTN/18-65 AC A0A1Q5KY65.1 #=GS A0YSH4_LYNSP/5-71 AC A0YSH4.1 #=GS A0A101K049_9BRAD/17-71 AC A0A101K049.1 #=GS W3AMI5_9FIRM/9-63 AC W3AMI5.1 #=GS A0A0G3H3N2_9CORY/10-64 AC A0A0G3H3N2.1 #=GS A0A372IBB4_9RHOB/13-67 AC A0A372IBB4.1 #=GS A0A1J4PY37_9ACTN/14-68 AC A0A1J4PY37.1 #=GS Q5CU92_CRYPI/92-145 AC Q5CU92.1 #=GS A0A1U7NXV6_9DEIO/6-60 AC A0A1U7NXV6.1 #=GS A0A089LR88_9BACL/6-61 AC A0A089LR88.1 #=GS A0A2N0IMS9_9ACTN/15-69 AC A0A2N0IMS9.1 #=GS A0A1S9B3J7_9BACT/14-68 AC A0A1S9B3J7.1 #=GS R5VLB5_9BACE/11-65 AC R5VLB5.1 #=GS I3ILV1_9BACT/13-66 AC I3ILV1.1 #=GS A0A1G9L418_9FLAO/8-62 AC A0A1G9L418.1 #=GS A0A1C9M042_9CAUD/12-64 AC A0A1C9M042.1 #=GS A0A370CGJ4_9COXI/3-59 AC A0A370CGJ4.1 #=GS A0A0C1R7I7_9CYAN/26-76 AC A0A0C1R7I7.1 #=GS A0A3G8FBI8_9CAUD/181-235 AC A0A3G8FBI8.1 #=GS G1WHM6_9ACTN/6-60 AC G1WHM6.1 #=GS A0A1M5AHK9_9BACT/5-60 AC A0A1M5AHK9.1 #=GS A0A1G7P3Y7_9SPHI/17-71 AC A0A1G7P3Y7.1 #=GS A0A2X3J3L9_9LIST/7-60 AC A0A2X3J3L9.1 #=GS A0A2U3CQI3_9BACL/7-62 AC A0A2U3CQI3.1 #=GS R7K9Y1_9FIRM/7-61 AC R7K9Y1.1 #=GS A0A2A2YQT0_9ACTN/13-69 AC A0A2A2YQT0.1 #=GS F0RD05_CELLC/12-66 AC F0RD05.1 #=GS A0A388TBU3_9BACT/14-68 AC A0A388TBU3.1 #=GS R5R2V5_9FIRM/10-64 AC R5R2V5.1 #=GS H6SMW3_PARPM/10-60 AC H6SMW3.1 #=GS A0A0H3GVF8_KLEPH/6-42 AC A0A0H3GVF8.1 #=GS A0A419XD27_9ACTN/5-59 AC A0A419XD27.1 #=GS A0A1H8MAK8_9SPHI/10-64 AC A0A1H8MAK8.1 #=GS R2QJ22_9ENTE/7-61 AC R2QJ22.1 #=GS U5RP97_9CLOT/12-66 AC U5RP97.1 #=GS A0A3A9DF63_9FIRM/9-63 AC A0A3A9DF63.1 #=GS A0A1J4QEN8_9GAMM/15-69 AC A0A1J4QEN8.1 #=GS C0AYD4_9GAMM/45-99 AC C0AYD4.1 #=GS A0A1J4QFV3_9GAMM/23-77 AC A0A1J4QFV3.1 #=GS A0A0T5NPG6_9RHOB/11-66 AC A0A0T5NPG6.1 #=GS Q6LZF5_METMP/5-59 AC Q6LZF5.1 #=GS Q4K5P6_PSEF5/13-60 AC Q4K5P6.1 #=GS A0A0H4W5L8_9BORD/25-79 AC A0A0H4W5L8.1 #=GS A0A1M7Q778_9ACTN/20-74 AC A0A1M7Q778.1 #=GS R5YDF2_9FIRM/8-62 AC R5YDF2.1 #=GS A0A084H291_METID/7-61 AC A0A084H291.1 #=GS A0A2K4ZA85_9FIRM/7-61 AC A0A2K4ZA85.1 #=GS A0A080M235_9PROT/38-80 AC A0A080M235.1 #=GS B1Y6W2_LEPCP/20-74 AC B1Y6W2.1 #=GS A0A1I7K120_9FIRM/14-76 AC A0A1I7K120.1 #=GS A0A1X7A6R8_9RHOB/33-86 AC A0A1X7A6R8.1 #=GS A0A396KTP5_9FIRM/6-60 AC A0A396KTP5.1 #=GS V7EN71_9RHOB/11-59 AC V7EN71.1 #=GS R6GTM0_9FIRM/26-82 AC R6GTM0.1 #=GS I4C8K1_DESTA/9-72 AC I4C8K1.1 #=GS A0A4Q5SRQ3_9BACT/16-70 AC A0A4Q5SRQ3.1 #=GS A0A1H3F5S2_9RHOB/10-71 AC A0A1H3F5S2.1 #=GS T0CKX4_ALIAG/9-63 AC T0CKX4.1 #=GS A0A419A2A5_9RHOB/14-69 AC A0A419A2A5.1 #=GS R5T0L2_9CLOT/20-76 AC R5T0L2.1 #=GS A0A2T6BAL7_9RHOB/31-85 AC A0A2T6BAL7.1 #=GS A0A1D6KQ79_MAIZE/26-79 AC A0A1D6KQ79.1 #=GS A0A1M7YG20_9FIRM/5-59 AC A0A1M7YG20.1 #=GS A0A1G8IQ84_9PSED/14-68 AC A0A1G8IQ84.1 #=GS A0A5C5G8N8_9RHOB/1-56 AC A0A5C5G8N8.1 #=GS 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