#=GF ID   IHD1_N
#=GF AC   PF30331.1
#=GF DE   IHD1 N-terminal domain
#=GF AU   Morveli N;0000-0003-2496-881X
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   TED:Q5A1B3_TED01
#=GF GA   27.00 27.00;
#=GF TC   27.10 38.60;
#=GF NC   26.10 18.20;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 8 -E 1000 -Z 90746521 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   20864472
#=GF RT   Mass spectrometric quantification of the adaptations in the wall
#=GF RT   proteome of Candida albicans in response to ambient pH.
#=GF RA   Sosinska GJ, de Koning LJ, de Groot PW, Manders EM, Dekker HL,
#=GF RA   Hellingwerf KJ, de Koster CG, Klis FM;
#=GF RL   Microbiology. 2011;157:136-146.
#=GF RN   [2]
#=GF RM   23516516
#=GF RT   A core filamentation response network in Candida albicans is
#=GF RT   restricted to eight genes.
#=GF RA   Martin R, Albrecht-Eckardt D, Brunke S, Hube B, Hunniger K,
#=GF RA   Kurzai O;
#=GF RL   PLoS ONE. 2013;8:E58613.
#=GF RN   [3]
#=GF RM   12388749
#=GF RT   Transcription profiling of Candida albicans cells undergoing the
#=GF RT   yeast-to-hyphal transition.
#=GF RA   Nantel A, Dignard D, Bachewich C, Harcus D, Marcil A, Bouin AP,
#=GF RA   Sensen CW, Hogues H, van het Hoog M, Gordon P, Rigby T, Benoit
#=GF RA   F, Tessier DC, Thomas DY, Whiteway M;
#=GF RL   Mol Biol Cell. 2002;13:3452-3465.
#=GF RN   [4]
#=GF RM   12845604
#=GF RT   Genome-wide identification of fungal GPI proteins.
#=GF RA   De Groot P.W., Hellingwerf K.J., Klis F.M.;
#=GF RL   Yeast 20:781-796(2003).
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents the N-terminal domain of the IHD1 family
#=GF CC   of GPI-anchored cell wall proteins found in Candida species.
#=GF CC   Family members include IHD1 (induced during hyphae development
#=GF CC   protein 1) and several PGA (predicted GPI-anchored) proteins.
#=GF CC   IHD1 was identified in the cell wall proteome of Candida
#=GF CC   albicans [1] and is part of a core filamentation response
#=GF CC   network induced during the yeast-to-hyphal transition [2,3]. The
#=GF CC   full-length proteins contain a signal peptide, this N-terminal
#=GF CC   domain, a disordered region and a C-terminal GPI-anchor signal
#=GF CC   [4]. The specific function of this domain remains to be
#=GF CC   determined.
#=GF SQ   15
#=GS A0A8H6C217_CANAX/23-92   AC A0A8H6C217.1
#=GS PGA50_CANAL/42-111       AC Q59MD0.2
#=GS IHD1_CANAL/19-90         AC Q5A8I8.1
#=GS PGA15_CANAL/23-92        AC Q5A1E1.1
#=GS C5M8J6_CANTT/19-90       AC C5M8J6.1
#=GS A0A8H6C178_CANAX/19-90   AC A0A8H6C178.1
#=GS A0A8H6C294_CANAX/23-92   AC A0A8H6C294.1
#=GS A0A8H6F559_CANAX/23-92   AC A0A8H6F559.1
#=GS A0A367YIP4_9ASCO/22-91   AC A0A367YIP4.1
#=GS PGA42_CANAL/23-92        AC Q5A1B2.2
#=GS A0A8H6C4M8_CANAX/33-102  AC A0A8H6C4M8.1
#=GS M3K4N0_CANMX/18-90       AC M3K4N0.1
#=GS PGA41_CANAL/33-102       AC Q5A1B3.2
#=GS C5MH66_CANTT/19-90       AC C5MH66.1
#=GS A0A8H6F6S1_CANAX/33-102  AC A0A8H6F6S1.1
A0A8H6C217_CANAX/23-92              .....IDYSYYGCNLDCYIASNQENTCGAHDDDVSDQQYHACLCMNYDYFTNLMNCNC..FDSNVYY..VSSSICSMAT...
PGA50_CANAL/42-111                  .aasr------VCNDNCYSFYEGELFCGKFDSNVSETDYLNCLCLNKQYRSNFEGCNC.kSESEVNF.fDWKSSCS---dis
IHD1_CANAL/19-90                    .radq------ICNDHCSNAYQKQQSCGGTDDVSSQSATLKCLCADESYWSELASCDCssYDSNVSAqdLRAYYCNVG-v..
PGA15_CANAL/23-92                   .....KDYSYYGCNSYCDKASDQEDACGYYDDDVSYQDYYGCLCGNEIFLSNLKSCDC..FTSIIAS..VSKSVCSKAT...
C5M8J6_CANTT/19-90                  .radd------DCNDHCTAALAKQNSCGGSGDAGTQSETLKCLCKDEDYWSELAQCNCsnYEDDITAedLRSYYCGIG-v..
A0A8H6C178_CANAX/19-90              .radq------ICNDHCSNAYLKQQSCGGTDDVSSQSATLKCLCADESYWSELASCDCssYDSNVSAqeLRAYYCNVG-v..
A0A8H6C294_CANAX/23-92              .....IDYSYYGCNLNCYIASNQENTCGAHDNDVSDQQYHSCLCMNYDYFTNLMNCNC..FDSNVYY..VSSSICSMAT...
A0A8H6F559_CANAX/23-92              .....KDYSYYGCNSYCDKASDQEDACGYYDDDVSYQDYYGCLCGNETFFSNLKSCDC..FTSIIAS..VSKSVCSKAT...
A0A367YIP4_9ASCO/22-91              ...gd------NCNDHCNNALQKQSQCGGSGDAGSQSQTLQCLCNDEAYWSELAQCNCsnYDESITAqdLRSYYCGI--gg.
PGA42_CANAL/23-92                   .....IDYSYYGCNLDCYIASNQENTCGAHDDDVSDQQYHACLCMNYDYFTNLMNCNC..FDSNVYY..VSSSICSMAT...
A0A8H6C4M8_CANAX/33-102             .....KAYAYYYCNSYCTQAVNDENSCGYYDTDVSNQEYYACLCTKSSYYNNLRSCDC..FTKVVYY..YSTSICSRAN...
M3K4N0_CANMX/18-90                  kradq------NCNDHCNTALQKQNACGGSGSANTQSDTLKCLCNDESYWSELAQCNCsnYDSSVSAqdLRSYYCGI--gl.
PGA41_CANAL/33-102                  .....KAYAYYYCNSYCTQAVNDENSCGYYDTDVSNQEYYACLCTKSSYYNNLRSCDC..FTKVVYY..YSTSICSRAN...
C5MH66_CANTT/19-90                  .radd------NCNEHCNNALQKQNECGGSGEAGTQSQTLQCLCNDENYWSELAQCNCsnYDSSISAqdLRSYYCGI--gg.
A0A8H6F6S1_CANAX/33-102             .....KAYAYYYCNSYCTQAVNDENSCGYYDTDVSNQEYYACLCTKSSYYNNLRSCDC..FTKVVYY..YSTSICSRAN...
#=GC seq_cons                       ...........sCNsaCspAhscENoCGuaD-sVSpppYhsCLCsccsYaSNLtsCsC..a-SsVsh..lpoShCShu....
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