GenomeNet

Database: Pfam
Entry: Imm40
LinkDB: Imm40
Original site: Imm40 
#=GF ID   Imm40
#=GF AC   PF15569.9
#=GF DE   Immunity protein 40
#=GF PI   Imm21; Imm21_;
#=GF AU   Zhang D;0000-0001-8535-7620
#=GF AU   de Souza RF;0000-0002-5284-4630
#=GF AU   Anantharaman V;0000-0001-8395-0009
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   [1]
#=GF GA   25.00 25.00;
#=GF TC   25.10 26.30;
#=GF NC   21.70 24.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF DR   INTERPRO; IPR029080;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A predicted immunity protein with an alpha+beta fold and
#=GF CC   conserved phenylalanine and tryptophan residues and a GGD motif.
#=GF CC   Proteins containing this domain are present in bacterial
#=GF CC   polymorphic toxin systems as an immediate gene neighbour of the
#=GF CC   toxin gene, usually containing a domain of the Ntox19 family
#=GF CC   [1].
#=GF SQ   43
#=GS A0A0M2VD29_9GAMM/1-82     AC A0A0M2VD29.1
#=GS A0A1G7UA32_9BACT/138-225  AC A0A1G7UA32.1
#=GS A0A1E8GK42_9LACT/21-108   AC A0A1E8GK42.1
#=GS C8PE91_9PROT/23-107       AC C8PE91.1
#=GS A0A180FVG9_9BACT/18-124   AC A0A180FVG9.1
#=GS A0A401ZWC5_9CHLR/143-231  AC A0A401ZWC5.1
#=GS A0A133Y7Z8_9BACT/20-112   AC A0A133Y7Z8.1
#=GS R5P663_9FIRM/20-109       AC R5P663.1
#=GS A0A180FVE0_9BACT/25-119   AC A0A180FVE0.1
#=GS K1M8H3_9FLAO/14-104       AC K1M8H3.1
#=GS A0A4V1AL48_9FLAO/13-102   AC A0A4V1AL48.1
#=GS A0A0F2JHJ1_9FIRM/1-55     AC A0A0F2JHJ1.1
#=GS C8PKE0_9PROT/30-114       AC C8PKE0.1
#=GS A0A3E1NJ82_9BACT/2-75     AC A0A3E1NJ82.1
#=GS R5NLP0_9FIRM/18-107       AC R5NLP0.1
#=GS A0A4Z0V4J8_9BACT/195-286  AC A0A4Z0V4J8.1
#=GS A0A3N2N5K0_9BACT/26-117   AC A0A3N2N5K0.1
#=GS A0A1I5J541_9BACT/16-114   AC A0A1I5J541.1
#=GS A0A4Y9J4B1_9LACT/16-111   AC A0A4Y9J4B1.1
#=GS A0A5C4XGJ8_9RHIZ/33-119   AC A0A5C4XGJ8.1
#=GS A0A1Z5HEK2_9GAMM/19-108   AC A0A1Z5HEK2.1
#=GS A0A3N2NFI2_9BACT/158-247  AC A0A3N2NFI2.1
#=GS A0A2K9EFQ1_9FIRM/17-106   AC A0A2K9EFQ1.1
#=GS Q7DD41_NEIMB/15-96        AC Q7DD41.1
#=GS A0A1N6LH85_9BURK/18-97    AC A0A1N6LH85.1
#=GS A0A6L6Q664_9BURK/34-125   AC A0A6L6Q664.1
#=GS A0A4Y9J057_9BACT/158-247  AC A0A4Y9J057.1
#=GS A7I3F8_CAMHC/12-101       AC A7I3F8.1
#=GS A9B0V1_HERA2/18-110       AC A9B0V1.1
#=GS A0A562L6K1_9FLAO/16-110   AC A0A562L6K1.1
#=GS A0A243SDP3_9FLAO/16-110   AC A0A243SDP3.1
#=GS A0A1X9NDF0_9GAMM/16-108   AC A0A1X9NDF0.1
#=GS R6TXD3_9FIRM/14-102       AC R6TXD3.1
#=GS A0A6B3UP30_9CAUL/18-106   AC A0A6B3UP30.1
#=GS A0A1G9PMK2_9FIRM/20-109   AC A0A1G9PMK2.1
#=GS R6T252_9CLOT/14-103       AC R6T252.1
#=GS A0A0H5DSF0_9BACT/16-108   AC A0A0H5DSF0.1
#=GS A0A3N2NBP2_9BACT/158-247  AC A0A3N2NBP2.1
#=GS A0A1H7KGX4_9FIRM/16-103   AC A0A1H7KGX4.1
#=GS A0A1M5YXE3_9DELT/16-108   AC A0A1M5YXE3.1
#=GS K1LNZ4_9FLAO/19-122       AC K1LNZ4.1
#=GS Q5F7U8_NEIG1/15-97        AC Q5F7U8.1
#=GS A0A3P1V5K3_9STRE/14-103   AC A0A3P1V5K3.1
A0A0M2VD29_9GAMM/1-82                .........m--------.----SKDQVLAVFDKFVDQR.ISVLGGD..........VYELV.DGA..PESN..YD.........NWYCERE.GGEPLD..VFALRSISQARDYVNNYN...N....PRGKETFYILV-a...........................
A0A1G7UA32_9BACT/138-225             ....gdriai--------.----SLNDSLYMIEILRQRL.FPILGGN..........ILKYE.SNQ..FSHT..HI.........NWSCDVI.--EPYS..DFVKRSCDIARREIEEVIstyS....TNEKDGLYV---ymt.........................
A0A1E8GK42_9LACT/21-108              .........d-LEGLGIY.AYAWKFSDFKKIIAYIEKNKsCRILGGD..........VYTYE.KDT..INLS..SN.........NWYISDD.--KAID..E----SYKITEDYIDKFY...K....INGNNYLYSVV-f...........................
C8PE91_9PROT/23-107                  .......lre---ELGFY.EIAWKFDDVMEVLKITKSKD.MVILGGD..........VYRLS.GNK..PIIT..GD.........GWYTNKG.DDDAF-..-------EVAIEYITKYR...A....RNGDDFAYC---pvi.........................
A0A180FVG9_9BACT/18-124              ....lseinp-----GSD.ETALSVSDALLALNILKDNQ.LIILGGDilsedeqgklVYVIH.YWG..YEYC..YL.........DWYCNRI.NNESEN..EYKKRSYDIAKRSIAIAD...T....IAK---------klnkkclisfvi................
A0A401ZWC5_9CHLR/143-231             .........s-LNDRGFS.EVGWLYKDIFEVLSIYQQEK.YKVLGGD..........VYRYS.NRD..IFHT..YD.........SWSTDSF.----KN..DLFEKGYSYTFSYIENYY...K....LHGDSYIYTLT-v...........................
A0A133Y7Z8_9BACT/20-112              ..........SLKNLGIE.GYAFPYQEALKIVQICKLLA.IPILGGD..........VYSMN.SST..IENS..DD.........NWYYDRT.PNESYY..DYVQNSCNKAESYISTFK...N....HFCDRPLFSFVI............................
R5P663_9FIRM/20-109                  ..........SLLSLGIN.EYAWDKDNIKDIFEELSKRK.IGILGGD..........VYKIE.NET..IKMT..FD.........SWYMNKD.---SSE..EFYQKSKLRALSYIEDYE...K....NNCGEFIYTIVI............................
A0A180FVE0_9BACT/25-119              dlsdpsvvkr--------.--GLTKQEAIDVLKYSEQIE.VAILGGD..........VYFLDhNGN..IDMT..HD.........NWYSDKR.DDETTE..EYIRRSINESKKYIGKYK...N....NSYKDFII----lfefv.......................
K1M8H3_9FLAO/14-104                  ..........SLVNYGVN.NIAFNIQDIKKVLNILKRLN.IAVKGGD..........IWIMR.NGE..LHLT..YD.........NWFCDQL.ENEMYL..MYVERSIEKTQTYIDNYP...L....DDH---------ayveivi.....................
A0A4V1AL48_9FLAO/13-102              .........f-LKSFGVN.NWAFTKDEALNVLKELEDVT.TPILGGD..........VWILQ.NEQ..MNHN..YD.........NWYCERL.PNEPYS..DYVHRSICKANNYINNYP...Q....NG----------niyfell.....................
A0A0F2JHJ1_9FIRM/1-55                ......mtny--------.--------------------.-------..........-----.--E..LNST..YD.........SWYINKD.ETKTWS..EYVAESKDKAVSYLNQYH...D....RNGDEFYYSVV-f...........................
C8PKE0_9PROT/30-114                  .......lre---EYGIY.DIAWKFDDVMEVLKITRGKG.MIILGGD..........VYRLN.GNE..PIIT..YD.........NWYTEEE.DDNAF-..-------ELAIEYITKYR...A....RNGDDF------aycpti......................
A0A3E1NJ82_9BACT/2-75                ...qlmnfya--------.------------------AR.IPILGGD..........IYECT.NNV..MSSN..YD.........NWYCDKL.PGEATD..EFLNRSIMKSKNYIEAYQ...N....KDPDKIFFVLV-p...........................
R5NLP0_9FIRM/18-107                  ..........SLLSLGIN.EYAWDKDNIKEIFEELSKRK.IGILGGD..........VYKIE.NEN..IKMT..FD.........SWYMNKD.---SSE..EFYQKSKLRALRYIEDYE...K....NNCGEFIYTIVI............................
A0A4Z0V4J8_9BACT/195-286             ..........SLESIGID.GFAYSKNEALRIVEEYYHSN.EAILGGD..........VYKVK.NGK..IKLT..YD.........SWYCERN.SAETIS..EYVNRSYKIARDYISRYH...S....TTNILFGFVI--e...........................
A0A3N2N5K0_9BACT/26-117              .........s-LELLGVN.GFAYPRKEALKIANGYFNSN.KPILGGD..........VYKLV.NGR..IEST..SD.........SWYCDKK.ESESSY..DYVVRSYHIACDYIRDYP...G....KANTFFSI----vie.........................
A0A1I5J541_9BACT/16-114              .........p-LYPLGID.GYAYIKKDALLIIHFFRDNC.FPITGGN..........VYTIS.KEK..ICYTegYN.........GWSCDRL.QNEPWN..DYVRRSYKIAYKYINSYS...RfpslFNRKEFLFSI--ny..........................
A0A4Y9J4B1_9LACT/16-111              ..........SLASLGMDgEYAWLAEDIWEVCEYLERNN.RIILGGD..........VISYD.GVN..LNST..YD.........SWHVSRE.ELNTLNilDYSKYSVNKAIDYITKYI...E....KNGLDYLYLLVI............................
A0A5C4XGJ8_9RHIZ/33-119              .......ehr--------.NWALSRPEALSALAELRKRG.IGVLGGD..........LLVFQ.SGR..FEHT..YD.........NWHCDPV.EHERND..VFVNRSINAAIGYVEAYP...E....G-ESPPFFVIV-p...........................
A0A1Z5HEK2_9GAMM/19-108              .....daeng--------.EVALKKSDAIKSLILLSDTD.IGVLGGD..........VYELE.SDG.yFRPT..YN.........NWYCDKN.-TDRKV..TFSEESRKVAYEYLSNYR...E....KIDSITMYVLVI............................
A0A3N2NFI2_9BACT/158-247             ..........SLESIGVD.GIAYTKSEALRIAEEYYNSN.IPILGGD..........VYLFN.NGN..IKPT..YD.........NWYCNRN.NSETSY..EYVARSYQVACDYIKKYP...D....NANI--------ffsiv.......................
A0A2K9EFQ1_9FIRM/17-106              .........s-LEPIGIF.EMAWKSQDALKVIDFLTSKG.YAILGGD..........VYKQD.ENG..IEST..YD.........SWYINKT.---VSK..SFIEESRIKSHEYIKEYS...K....NNGDCYLYSII-f...........................
Q7DD41_NEIMB/15-96                   ..........SLIGIGIR.EAALPVPIAIDILNLFINER.ILVLGGD..........IYIKK.DNY..FYQT..YD.........NWYYEG-.------..------------------...-....------------snlfnsidkamhylsqiklenayvsfv.
A0A1N6LH85_9BURK/18-97               ..........SLEDMGLK.EAALDLSEAGQALDLFAGQK.WLLLGGD..........VYRAT.SDGrsLEPT..YD.........NWFYEG-.------..------------------...-....------------nnvdegisaardflhslrdrslf.....
A0A6L6Q664_9BURK/34-125              ..........SLERIGVR.NWALEREAALKALQQLSAIG.VAILGGD..........VYVVQ.GEN..IEPN..YD.........NWYCNRE.AEENEA..DFVARSVAKAQRYIVNYL...T....SAN-NVLFAIV-p...........................
A0A4Y9J057_9BACT/158-247             ..........SLESIGVD.GIAYTKSEALRIAKEYYNLN.IPILGGD..........VYFFN.NGN..IKPT..YD.........NWYCNQN.NSETSY..EYVARSCQVTCDYIKKYP...D....NANI--------ffsiv.......................
A7I3F8_CAMHC/12-101                  ....elffkn------LN.EIAYNYENVIKKIKVLELKG.FVILGGD..........VIKYD.GDT..VKYT..YD.........NWYFNPD.--EYSY..DILKYSAQKAIDYIEKYN...E....IDK---------dcfyslcv....................
A9B0V1_HERA2/18-110                  ..........LLSELGTQ.EYALDQQDAMNAIVIIEDLA.IPILGGD..........VYLQS.LEG..IEIS..YE.........NWSINRQ.PGESLD..NYVRRSCAYTRNYIARFP...V....QAEKLPLFVLVL............................
A0A562L6K1_9FLAO/16-110              ........pi--HEAGIN.SWAFLKKEALEILNRLEELN.VFILGGD..........VYVLS.YDF..FKPN..YD.........NWYCNRF.SNETDI..EFTKRSVKTAKDFIMNYN...I...vDTEASQIF----fafvl.......................
A0A243SDP3_9FLAO/16-110              .........p-LHEAGIY.NWAFLKKDALEVLNRFEELN.VFILGGD..........VYVLS.YDF..FQPN..YD.........NWYCNKF.SNETDI..EFTKRSVKIAKEFIMNYN...I....AYT---------easqiffafvl.................
A0A1X9NDF0_9GAMM/16-108              .........p-LNRLGEK.SWALSKYQALKALHQLKLEG.AVIIGGD..........MYQLS.DGE..LQPN..GD.........SWYFERF.CGESDE..EFSQRTVDCTFNYLVEYE...H....PNKLETYFAF--if..........................
R6TXD3_9FIRM/14-102                  .........d-LTSDGIN.NYAFDLPSAMAFICEAVSHG.FLILGGD..........IIIRE.GKH..YIES..CD.........NWYCNENnPMETAQ..----KAM----EY-----...-....------------lsayylrncdsdkkwwvsvlt.......
A0A6B3UP30_9CAUL/18-106              .........s-LEPFGVQ.GWALPQVDALAAIERLRGLG.VPVVGGD..........AFERK.SGE..LVLA..YA.........NWCCELF.PGEEIA..SYVDRSALVARRFVSEYR...G....------------rdpyfaiv....................
A0A1G9PMK2_9FIRM/20-109              .........n-LESIGIS.EIAWKSEDIIKVIDFLVDKK.YVILGGD..........VYSLN.GNI..LEST..YD.........SWYIDGS.---VNQ..SLLEDSRKKACEYINKYV...K....NNGNYYIYSVV-c...........................
R6T252_9CLOT/14-103                  ...kslfisq-------Y.ELAWKITDADDFIEDAILNQ.VIVLGGD..........ILD--.-AN..LQYT..LD.........NWYYEPD.KSISRK..VNSLQSCNCMKKYIERYI...E....RNGSDFY-AII-ic..........................
A0A0H5DSF0_9BACT/16-108              ..........SLEKFGMN.DLAWEKDAAVTLINSLMNDD.IGILGGS..........VYKID.SNN..FMPM..YD.........NWSCNPD.SKEVSK..DFNFRSKTRALEYINKYP...I....YLDERILFSLV-f...........................
A0A3N2NBP2_9BACT/158-247             ..........SLESIGVD.GIAYTKSEALRIAEEYYNSN.IPILGGD..........VYFFN.NGN..IKPT..YD.........NWYCNRN.KSETSY..EYVARSCQVTCDYIKKYP...D....NANI--------ffsiv.......................
A0A1H7KGX4_9FIRM/16-103              .........r-LKVIGFN.EYAFSYEQIKKIIELLRIKK.LSILGGD..........VYMKK.GEK..IIIT..PD.........SWYINKD.---KIN..D-YEYSYKKTINYIEIFE...S....KE-EDYIYSIVI............................
A0A1M5YXE3_9DELT/16-108              ..........SLENIGVN.NWALDNKQALEVLDEFERQG.IAVLGGD..........VYEIV.DGI..PESN..YD.........NWYCEQY.DDEPFL..DFSKRSIAKAREYINNYK...Q....SSSKSVMYTIV-a...........................
K1LNZ4_9FLAO/19-122                  ....gvnpds-------D.EVALTVSDALVAVNLLEKEK.MPILGAD..........VLLEY.EEG..LKYL..YQilgdeyiylNWYCDEL.DNENEE..EYIQRSHNIAKEYINSIA...K....IEKEYNI-----qcyvvlvl....................
Q5F7U8_NEIG1/15-97                   ..........SLIGIGIR.EAALPVPTAIDILNLFINER.ILVLGGD..........IYIKK.DNY..FYQT..YD.........NWYYEG-.------..------------------...-....------------snlfnsinkamhylsqiklenayvsfvl
A0A3P1V5K3_9STRE/14-103              .........n-LSEIGIH.NYAYSWECIGEILDEIKSSK.LIILGGD..........VYISD.DAE..LILT..LD.........NWYYNLK.--KSPL..DY-SQSLDRAREYIYNYI...E....QNDRDCYFSFVL............................
#=GC seq_cons                        ...........L.thGlp.phAashp-Alcllphhpppp.hsILGGD..........VYhhp.ssp..lp.T..YD.........NWYssct..tEs.t..-ahp+ShphAhcYIppY....p....pstt..hh................................
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