#=GF ID   Imm43
#=GF AC   PF15570.12
#=GF DE   Immunity protein 43
#=GF PI   Imm24;
#=GF AU   Zhang D;0000-0001-8535-7620
#=GF AU   de Souza RF;0000-0002-5284-4630
#=GF AU   Anantharaman V;0000-0001-8395-0009
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   [1]
#=GF GA   25.00 25.00;
#=GF TC   25.10 25.10;
#=GF NC   24.00 24.70;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 90746521 --cpu 8 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0767
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF DR   INTERPRO; IPR029079;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A predicted immunity protein with an alpha+beta fold with
#=GF CC   conserved tryptophan, proline, aspartate, serine and arginine
#=GF CC   residues.  Proteins containing this domain are present in
#=GF CC   bacterial polymorphic toxin systems as an immediate gene
#=GF CC   neighbour of the toxin gene, usually containing a domain of the
#=GF CC   Tox-AHH family of HNH/Endonuclease VII fold nucleases [1]. The
#=GF CC   gene for this toxin is also found in heterogeneous poly-immunity
#=GF CC   loci.
#=GF SQ   46
#=GS I9B755_BACFG/13-223      AC I9B755.1
#=GS A0A1Y4HXN3_9BACT/14-227  AC A0A1Y4HXN3.1
#=GS Q7N9J9_PHOLL/22-223      AC Q7N9J9.1
#=GS R9HWU8_BACUN/17-220      AC R9HWU8.1
#=GS A0A1W1XYS9_9NEIS/9-205   AC A0A1W1XYS9.1
#=GS A0A559JQE0_9BACL/1-213   AC A0A559JQE0.1
#=GS D3V9F5_XENNA/7-208       AC D3V9F5.1
#=GS E8JZH1_9STRE/26-212      AC E8JZH1.1
#=GS A0A6I2MN35_9FLAO/7-205   AC A0A6I2MN35.1
#=GS E8JZG8_9STRE/14-211      AC E8JZG8.1
#=GS A0A089HTU2_PAEDU/9-219   AC A0A089HTU2.1
#=GS G2Z5Q2_FLABF/10-222      AC G2Z5Q2.1
#=GS A0A3S3TUZ1_9FLAO/14-217  AC A0A3S3TUZ1.1
#=GS D3V9F2_XENNA/1-64        AC D3V9F2.1
#=GS I9U1E2_PHOVU/13-223      AC I9U1E2.1
#=GS D3V9F4_XENNA/1-70        AC D3V9F4.1
#=GS A0A3E4MLX4_9BACT/13-223  AC A0A3E4MLX4.1
#=GS A0A323V296_9RHOO/24-198  AC A0A323V296.1
#=GS A0A2S5CYG5_LYSSH/5-207   AC A0A2S5CYG5.1
#=GS A0A542D496_SERFO/15-218  AC A0A542D496.1
#=GS A0A917J4U2_9BACT/1-70    AC A0A917J4U2.1
#=GS A0A4R0NHK0_9SPHI/30-220  AC A0A4R0NHK0.1
#=GS A0A3P3VY20_9MICO/18-202  AC A0A3P3VY20.1
#=GS A0A119A800_9PSED/9-200   AC A0A119A800.1
#=GS A0A7Z2VW55_9BURK/26-207  AC A0A7Z2VW55.1
#=GS A0A1G6KPH3_NIADE/8-221   AC A0A1G6KPH3.1
#=GS A0A327QP71_9BACT/9-222   AC A0A327QP71.1
#=GS A0A3S4ST30_9FLAO/9-223   AC A0A3S4ST30.1
#=GS A0A1Y4HTX7_9BACT/14-227  AC A0A1Y4HTX7.1
#=GS A0A917IR66_9BACT/1-93    AC A0A917IR66.1
#=GS A0A2S5CYJ7_LYSSH/5-209   AC A0A2S5CYJ7.1
#=GS A0A975YM35_9VIBR/12-116  AC A0A975YM35.1
#=GS A0A2S5CYG2_LYSSH/1-203   AC A0A2S5CYG2.1
#=GS V8G9I0_9BURK/19-209      AC V8G9I0.1
#=GS A0A3E4MME6_9BACT/14-223  AC A0A3E4MME6.1
#=GS A0A917MA99_9SPHI/13-223  AC A0A917MA99.1
#=GS F0P2G1_WEEVC/31-165      AC F0P2G1.1
#=GS A0A559JQA5_9BACL/71-281  AC A0A559JQA5.1
#=GS A6EH29_9SPHI/24-222      AC A6EH29.1
#=GS A0A917J3C7_9BACT/9-150   AC A0A917J3C7.1
#=GS Q7N9I7_PHOLL/22-223      AC Q7N9I7.1
#=GS A0A2S5CYB9_LYSSH/8-202   AC A0A2S5CYB9.1
#=GS D1PUV2_9BACT/5-180       AC D1PUV2.1
#=GS A0A173MDB7_9BACT/9-222   AC A0A173MDB7.1
#=GS D3V9F1_XENNA/7-52        AC D3V9F1.1
#=GS A0A444GLV5_9FLAO/9-201   AC A0A444GLV5.1
I9B755_BACFG/13-223                 .........................................idk----LPKGLLEYGKSD..VCDTYDESKRQKFQ..N.HgQWM-WKDK-..----N..GWEENLPSVLYLVCNK.kPGILQFDFLdkCSIKLKI.VSEEFLSLLQENGFI.DK..YDVATV.......K.VVNKKN.E...T.L..TD.KKYYALRINH.fDNDSF..HFG.KGIT.Y..QSDFQKkl...gtCFTV.....................YPDMK.LK...DCS.I..K.QNFFVLDSV.E.Y.GDGIIFREKVLDKVL--NLYKPEIYKLSDYSKLWI-------dekfypy................................................................
A0A1Y4HXN3_9BACT/14-227             ...........................................a-RIEEFKLLPLYEDYW..LSDKYCPKKQVPIL..G.D.-WVMYYPPK..DGFPS.yDERFKMPEILYLHIKS..KVQPSFDWF.pQNYNLKI.VSESFLNFMISNQLY.DR..FEATEL.......R.VFGTDG.K...E.F..IE.KKYFVIRICE.fDDNKF..DFH.IENK.K..RAIGCNk.....yNNFL.....................YPDMQ.LK...NYN.G..K.QNIFFLDEF.C.Y.QNSIILTADGKDYVM-QNFNLPELYKLEDYRFVWNNRYNIE-q......................................................................
Q7N9J9_PHOLL/22-223                 ............................................MNDYNSSLMPRYLHAI..VDTE-------NQI..N.E.KWD-YEGSR..HDIPY.yLLDKECPNTLYLLCNK.nIGKLWFNYY..QHNMAHI.LSDRFFDIINEFKLS.DH..VLKKLI.......A.TSIKDG.K...T.I..-N.NSLNYLFFTD..KELFL..NEK.YSIL.E..KDKYG-.......NLIP.....................-HKLS.FH...NES.L..N.YDIFSIRTT.L.L.AGFIFISEKVANRLIKENIKRIKLIKLDEVLNHYCVDFKYDI.......................................................................
R9HWU8_BACUN/17-220                 .......................................gtpia---------PPYIDST..FTEEIKSKNPYNNPvyS.N.DWFNYSPMR..AGKPVplTDNYKLPTHFYWICSN..VKRLETDYY..SHSKGVI.LSSCLFEFLKQFKCY.DE..YDICEV.......T.PLSRKL.A...H.I..SD.KKYYFIRFKHlaYNLFI..DLE.NSNR.I..KRMNKV......iTSYL.....................YLDFQ.LK...EQT.A..Y.PDIFWMKN-.-.-.--ILVAKDSVADLINGNGFSGFRMVELKDFVDEYT-------fr.....................................................................
A0A1W1XYS9_9NEIS/9-205              .redrgcplgmlqgelhprffldakkfsygtypwyanpygrfge----------------..--------------..-.-.---------..-----..--VEKFPEGLCFITSD..-KLYNFAVR.sDSFAYHL.ISEDFLACIQRAGGSlLD..F--QRV.......D.VKSRVG.K...D.I..AE.RQYFAAKFPR..HDVSIaeDSD.LSQF.L..VKAGSS......tKRI-.....................-KKLA.IS...PKF.S..-.DTIFCIKGI.DpA.NDTIFCSEDFYLLAKDMDFKGVEFIRLEDV------------vwp....................................................................
A0A559JQE0_9BACL/1-213              ............................................MEGKSGRGVPIFMKSV..LAEEFNEKKPMPGM..D.Y.KWVKSQGT-..-----..-GKAEFPDKLYLVCKE..-RLLLFDYF..ADFQGFI.ISTEFLKLFNRYSSM.EG..YQLVPL.......E.TISWKG.K...K.I..TE.KQYYNLFPYH..KEKWV..DYQ.TSVF.Q..IKQGKTl.....eDVINkngl.............linkYEEIK.LI...ESA.M..N.KEVFTLSGA.H.L.NSFLFCSEEFKHELEKAKLVGIDFISIEEFPTYYNKKYLYF-l......................................................................
D3V9F5_XENNA/7-208                  ............................................MNDYKSSLIPRYLHAI..VDVK-------KQV..N.K.NWD-YEGSD..YSFPY.dMEQPDCPEKLFLLCNR.nIGALKFNYY..RHSRAHL.MSDYFFDFLKPFRMS.DF..ICKKLL.......A.TSIKDG.E...T.I..-R.DDLNYIYFTN..NDDFL..DFD.KSKL.E..EDRYR-.......GVIP.....................-HKLV.FS...EKV.L..S.YDIFAITGT.L.L.SGHIFLSEMVAEKFFEKKIAGLKLIKSEDAFKEYCLDYGYDI.......................................................................
E8JZH1_9STRE/26-212                 ......................................slgevg----------------..ISEVFNPKKTHPDF..D.F.SWSWFVKG-..QEIPP..-----MPEKVYVCLKK..ARSVTFDFL.pYGYNFFI.MSARFLEFIKKYGFN.YN..FGMSEA.......I.IVNTKG.E...L.L..TN.EVYYLVRIVSweIEDEI..VYP.D--L.G..RDEKG-.......--FS.....................---LE.-A...YTN.S..D.KDILLSSKY.K.Y.MEAFMVSENLKDKIL-ENFSLPFLYSLEEWKELNNLDSY---wd.....................................................................
A0A6I2MN35_9FLAO/7-205              ..........inwdynhsedmerdafhipfensdkastlflssr----------------..--------------..-.-.---------..-----..-YKDKLPDYILFRANF..NIIPEFDYP.lTDLNVPI.LSDRMISILNEIDDF.EA..IFTKVImlddtylEsIYDETG.NlksE.I.kTA.LNYKALTIVN..REDCF..DFE.NSIY.Q..PSELNPn....kpGFI-.....................-EKLV.LK...STE.Y..L.PPIFRIRET.P.-.-SKLLITESAKSALEKNDLKGCVFEEVE--------------tts....................................................................
E8JZG8_9STRE/14-211                 ..........................................md--KAEKMGLPRVSSGAvgISEKFNPKKTHPDF..D.F.PWSWFVKG-..QEIPP..-----MPEKVYVCLKK..ARGVTFDFL..PYNDFFI.MSARFLEFIKKYGFD.HD..FGMSKA.......I.IVNTKG.E...L.L..TN.EVYYLVRIVDweIQDEI..VYP.DLAL.D..EDDYSL.......E---.....................-----.-A...YTN.S..D.KDILLSSNY.N.Y.SGAFMMSENLKEKIL-ENFSLPFLYSLEEWKELNNSDFYWD-.......................................................................
A0A089HTU2_PAEDU/9-219              ............................................MEKKSGRGVPIFLNAV..LAEEYNQKNPMPDM..D.Y.EWNFSSGI-..-----..-RKVNFPDHLFLICNE..-RLLIFDYY..PHFDGFI.VSNEFLKVFRGYSSM.EG..YQLVPL.......E.TLSWKG.K...K.I..TE.KKYYYLFPYK..EEDWV..DFQ.ASKY.V..VEKGETv.....eDIIStggl.............fikkIEKII.LK...EPE.I..D.KEVFTLRGS.T.L.TNYLFCSEIFKKEIEKEKLVSIDFIPLEQFPDYYNKK-----nll....................................................................
G2Z5Q2_FLABF/10-222                 ..........................................ti--PRTPKGFPLLEDRW..LREKYYPSKNQEEM..D.Y.KWMKYNPLK..DAFPP..KGDLKLPDELFFIVQK..QKELLFDFM.nYHFNLFI.VSDVFLKLIQEYRLD.LK..YEISKL.......K.IVHKNE.K...E.L.kCD.KDYYALRVST.hDDDLF..DYV.EDGK.K..RASGAR.......DFFL.....................YPNLK.LK...PDV.Q..D.KGIYFLNEF.C.Y.HQTIVVNEELKKTII-KNFYSPELYKLEDFAQVYNNSYKLEL.......................................................................
A0A3S3TUZ1_9FLAO/14-217             ...........dgipvffearmfeqpivgnafskensiyynwmk----------------..--------------..-.-.---------..---PG..FNEYELLPEYYLYTKC..-VDLEFDYY..KFANHYI.ISEDFLLLISKYNVA.--..YTKGRV.......Y.VFSSEDnS...E.L.aLR.KKYFFVKFDY..AEGLI..DYT.NSIY.E..VSLSDK......gEPIVhngv............kyirkYEKIE.LI...DEN.I..Y.SEVFLIKDP.I.L.GFNLFCTDQFKIDAENMKVYALMFVALPDYL-----------dfvkys.................................................................
D3V9F2_XENNA/1-64                   ..........................................mr----------------..--------------..-.-.---------..-----..----------------..---------..-------.---------------.--..------.......-.------.-...-.L..IR.DDLNYIYFIG..NDDFL..DLN.NSEL.E..EDRSG-.......SLMP.....................-HKLI.IN...NP-.S..N.IDVFTIRST.L.L.ADF---------------------------------------fdf....................................................................
I9U1E2_PHOVU/13-223                 .............................idklpkglleygksd----------------..VCDIYDESKRQKYQ..NlG.QWM-WQNN-..----D..GWRENLPPVLYLVCNK.kPGILQFDFLdkSSIELKI.VSEEFLSLLQENGFI.DK..YDIATV.......K.VVNKKN.E...S.L..TD.KKYYALRINH.fDNDSF..HFG.KGIT.Y..QSDFQKkl...gtCFTV.....................YPDMK.LK...DIS.I..K.QNFFVLNSI.E.Y.RDGIIFRERILDKVL--NLYKPEIYKLSDYSKLWID------kgfypy.................................................................
D3V9F4_XENNA/1-70                   ...........................................m----------------..--------------..-.-.---------..-----..-KELECPDSLFLLCNR.nVGALNFNYY..FHGSGHI.ASNKFIDLFNGLKTC.KI..ISKNLI.......A.TSIKDG.S...V.I..--.----------..-----..---.----.-..------.......----.....................-----.--...---.-..-.---------.-.-.------------------------------------------nlsf...................................................................
A0A3E4MLX4_9BACT/13-223             ...........................idklpkgllefgrsdvc----------------..--DTYDESKRQKFQ..N.HgQWMWKNKN-..-----..GWRENLPPVLYLVCNK.kPGILQFDFLdkYSIKLKI.VSEEFLSLLQENGFI.DK..YDIATI.......K.VVNKKN.E...S.L..TD.KKYYALRINH.yDNDSF..HFG.KGIT.Y..QSDFQKkl...gtCFTV.....................YPDMK.LK...DSS.I..K.QNFFVLDSI.E.Y.GDGIIFRERVLDKVL--HLYRPEIYKLSDYSKIWNKR-----gcyly..................................................................
A0A323V296_9RHOO/24-198             ..................nhdwtwdefdpdpdkfnitlnyeyrs----------------..--------------..-.-.---------..-----..---------------K..NPLIDFDFW..NDFR--I.GSDAFCELCDSFGT-.-Y..VRRVPL.......K.IIQSNG.K...P.T..-V.KKYNYLLWRD..WLSII..DTE.KSDY.E..ISRDPRtgeieydKYFSei.................pfYEEITrFIpnlDKI.G..K.KSVFKCVD-.-.I.HCEVVCTETFRDACIERGFLGLDFIPIEEFK-----------mi.....................................................................
A0A2S5CYG5_LYSSH/5-207              .....................................mivkdnv-------KSPIFLKGV..IHESFDETKYNEGM..G.Y.EWNKIF---..-----..FQKQEMPKDLWLITNN..--KIEFDYY..EGFNGHI.ISSDFFTLMNQVNTL.QK..YVISNL.......Q.VVSSKG.K...S.K..VK.KPYYFIKYYN..REDFV..DYE.KSEFtK..RDVPEN.......KVFDiny..............mvgkYQKIV.LQ...E--.N..D.RDVFCLNDL.K.L.ARYLFCSERFKQLCEEKQMKGIQFLELEDVPQYFS-------syd....................................................................
A0A542D496_SERFO/15-218             ............lvmsdlylvmndynerarflkgvfdvvktypv----------------..--------------..-.-.-----KESK..YDFPY.yLEDENCPDDIFLNLEE..GKDISFDY-..RKDQGHI.FSSNLWELISKFRMP.EK..YI-KNL.......S.ISCCGE.S...V.T..SD.KRYKYVFFPA..-HDFI..NYK.ESVL.L..DVTRG-.......SLVP.....................-NKII.FN...ESSlN..D.YDVFQLSSK.VvI.GLRLVINEDVKLSIENNGFTGFKIVPLEQALAEYCKDYSFD-p......................................................................
A0A917J4U2_9BACT/1-70               ...........................................m----------------..--------------..-.-.---------..-----..----------------..---------..-------.---------------.--..------.......-.------.-...-.-..--.----------..-----..---.----.-..-----K.......DFFL.....................YPNLT.LK...TPV.E..G.KGIFALFSF.C.Y.NETLVFTKEVKDEIL-ARFYAPGIYKAEDYPSVFNNQYKWDV.......................................................................
A0A4R0NHK0_9SPHI/30-220             ......................epitgyafskensiyyewmkpg----------------..--------------..-.-.---------..-----..FNDYELLPEYYLYSKC..-VDLEFDYY..KFANHYI.ISEDFLAVISKYNV-.-A..YTKGRV.......Q.VFSAED.N...SqL.vLR.KNYFFVKFDY..INDLI..DYT.KSIY.E..VSLSDK......gEPIVhngv............ryirkYEKIE.LI...DEN.I..C.SEIFLIKDS.I.L.GFNLFCTGQFKIDAENMKVYALMFVALPDYL-----------dfvkys.................................................................
A0A3P3VY20_9MICO/18-202             .............................leaegvppeasgmig----------------..ISERFDTKRTHPDF..D.F.PWAATYSP-..EPL--..---PPMPEHVTICLKR..VNAVHFDFI..PYGDFFI.LSERLLVFLEDHRFD.YA..FDRSRA.......S.IVNTKG.Q...P.L..TD.ETFFLLRR--..-----..---.----.-..------.......----.....................-----.--...---.-..-.---------.-.-.------------------------------------------ddlrigdevewvdgdsdgdgeqaitrsekrvllsdedgyesclfvdatlkatleqrfrtvhlftaaewnrl
A0A119A800_9PSED/9-200              ..............reesgcqagmlnaalcdkfyedmdsieygd----------------..--------------..-.F.PWYSEKGR-..----S..KNRTPLPEGMVLISKD..-KYYDFDIR.gVSRFFYI.VSDEFLDLCFS--LSvEV..IDSAKI.......K.VLSIKG.E...S.I..SK.KNYNVVIFNE..LDARL..DTDpTSTF.V..EDEGR-.......-PIR.....................FKKLV.I-...PHG.L..G.LDLFKYSRM.L.SgSDSLICSEQFKIKA--DNFKGVNFFSLDG-------------liws...................................................................
A0A7Z2VW55_9BURK/26-207             ...............ltpsetewelfvpnpfniniknkyilkii----------------..--------------..-.-.---------..-----..---------------DpdIENIAFD-M..DSSDQKY.VSKQFLNVCDSL--S.IS..YRAIPL.......E.ILFTDG.R...K.T..-T.KDYFFFLPGK..NIELL..DRK.KSSF.K..EEKVLGsnqtemnGVFPsc.................piYSKIE.RF...VPV.QtyT.ENLFFCIEI.F.-.--EIVCTESFRKIALQKNLIGIDFLPIDEDYQ----------ynpwn..................................................................
A0A1G6KPH3_NIADE/8-221              .................................nnynlptssas-------------NGV..LAEQYDANTPFPPM..K.Y.SWTK-----..---PR..DPDRIYPSELFYILKG..ETTFNIDYS..SFWDGYI.ISEKFKSLLDSANC-.PH..YKSVKL.......A.VINTKG.E...D.I..AKgERFFFIDMRS.aVQDII..DYA.HSSF.I..LNEDM-.......--IKirgltveavrksgdyfgniksYEQLS.LK...QEN.I..R.FDIFKLKDL.A.V.ND-LVCNEQCCAKIR-ESFNTIECINLMDMRP-YNNRF----a......................................................................
A0A327QP71_9BACT/9-222              ............................................NRTQLPTGYPAKDDTI..LKLSFDPKKPKLMP..G.Q.PWKQFNIHT..MPFPP..EEMYQFPSSMYLVVTRklKDPIKFDYY.dYAQGVKL.VSAGFLTFIQEAGLTeEH..YEIATL.......H.IINEAG.E...A.L..TN.DTYYALRFGQ.fNDASF..DFP.VDTK.K..RAAGLQ.......GHFL.....................YPGLQ.LN...NPT.-..S.QQVFALQNF.C.Y.LNTLIFTAQAARKAL-QQFHYPALYPAEEFPFVFNNQHNWSI.......................................................................
A0A3S4ST30_9FLAO/9-223              ............................................NRTRVPEGYPLKDDFI..LKNSFKKDKAKEIP..T.Q.QWKLFNPFK..MKFPP..VDDYKLPSEMYMVIIKvsNKKIFFDYY.gYSNNVAF.ASDKFLGFLQKNGLDdSY..YEKAKL.......R.VIDLEG.N...V.L..TS.GDYWALRFGK.fDDHLF..DFH.PEAK.K..RVAGVK.......NYFL.....................YPEMD.LV...KTI.P..S.KNVYYLSEF.C.Y.HTSIVFSKDVKEEVI-EKFYSPEIYKVSDFPYVYNNQYKWDI.......................................................................
A0A1Y4HTX7_9BACT/14-227             ...........................................a-RIEEFKLLPLYEDYW..LSDKYCPKKQVSIL..G.D.-WVMYYPPK..DGFPT.yDTRFKMPEILYLHIKS..KVQPSFDWF.pQNYNLKI.VSESFLNFMISNQLY.GR..FEATEL.......K.VFGKDG.K...E.F..ID.KKFFVIRICE.fDDNKF..DFH.IENK.K..RAIGCNk.....yNYFL.....................YPDMQ.LK...NCN.D..K.QNIFFLDEF.C.Y.QDSIILTTDGKDYVM-QNFNRPELYNLEDYRFVWNNQYNIE-q......................................................................
A0A917IR66_9BACT/1-93               ..........................................mi----------------..--------------..-.-.---------..-----..-------------TKS..LPKLVVDFD.iIDTDTWL.VSERFFNLIIEENLLaST..YESSKL.......T.LISHQG.K...P.V..SN.KQYYLLRFFK.rYDDQI..DFD.KS--.-..------.......----.....................-----.--...---.-..-.---------.-.-.------------------------------------------psikppkkaqvgmp.........................................................
A0A2S5CYJ7_LYSSH/5-209              .....................................miindkl-------TTPIFLDGV..IHEHFDETMYHEGM..G.Y.SWN--RHF-..-----..FNKDDFPKELWLITTS..--KIEFDYY..ESFLGHI.VEEQLLNLILDSKSL.NE..YVIAKL.......N.IVNTKG.K...S.KvkKN.KNYYFIKYFD..GISLV..DYE.KSEF.T..SREVPK......nKNFKsegv.............fvekYQKIV.FK...NT-.-..D.FDVYRLKDL.R.L.STFLFCSDKFMQRCIQLKLIGLKFVELNEVVAHIN-------sr.....................................................................
A0A975YM35_9VIBR/12-116             ..................ylvfkrpinndtdeikkryrfidlnk----------------..--------------..-.-.---------..-----..----------------..---------..-------.---------------.--..------.......-.------.-...-.-..--.----------..-----..---.---T.D..WQYGKR......nQIVP.....................TGNVV.LN...ENA.F..D.YDILELSEFsV.V.HSQIVISEKVKLSIEKHAVKGVKLIGLNKGIN----------ehlvdnhiei.............................................................
A0A2S5CYG2_LYSSH/1-203              ....................................mlvkdevn--------SPIFLKGV..LHEEFNETKFNEGM..D.Y.KWN-SIF--..-----..FEKADFPKTLWLITTN..--KIEFDYY..EDFSGHI.VSNKFLSLMKESNYL.QH..FVISSL.......N.IVSTKG.K...P.K..VK.EPYFFLKFYE..REDIV..DYD.KSEF.K..TREVQE......nKSFNingi.............fvekYRRIT.LK...DT-.-..D.RDLFCLNDL.K.L.INYLFCSEKFKHLCKINDIKGIRFIEINDIPQYFS-------sl.....................................................................
V8G9I0_9BURK/19-209                 ..............................kdlniplsssgdig----------------..ISEVFNSKNTHPDF..V.F.PWV--GGT-..---PI..KTVASMPKELVICLKR..VKSISFDLL..SYSNFLI.VSKALYDYMTAHGFD.YD..EDKSCA.......R.LVNPKG.D...A.L..TD.ETFYLLRCYW..WN--I..KHN.EVQL.I..RDEKNN.......DVIA.....................-----.-A...STD.S..T.KDFLMTDHR.E.Y.CYELFVNADLKQEIT-TLFRNPMLFSLKEWN-----------elnsddwg...............................................................
A0A3E4MME6_9BACT/14-223             ..........................gklpkglleygrsdicdt----------------..----YDESKRQKFQ..NlG.QWM-WQNN-..----D..GWRENLPPVLFLVCNK.kPGILQFDFLdkSSIELKI.VSEDFLSLLQENGFI.DK..YDIATV.......K.VVDKKN.E...S.L..TD.KKYYALRINH.fDNDYF..HFG.KGIT.Y..QSDFQKkl...gtCFTV.....................YPDMK.LK...DSS.I..K.QNFFVLNSI.E.Y.KDGIIFRERVLDKVL--NLYKPEIYKLSDYSKLWI-------dndfypy................................................................
A0A917MA99_9SPHI/13-223             .......................................qttft------------SDGV..LAEGYDQKNPFPPM..K.Y.SWTK-----..---PR..DLNRVYPSELNYIFKG..-GIFKLDYA..SFWDGYI.VSREFKELIDILRC-.PV..YKSVRL.......N.VLNIKG.E...R.I.sNE.GEYFFLDMRH.sVQDVV..DYP.KSLF.F..LNEDM-.......--IKmrgltieqvkstgdyfgnikaYEKIA.LK...EEK.V..D.FNIFKLKDI.A.V.HD-LVCDEECYLKIR-NSFDRVKCINLTDL-KEYNERFGW--sn.....................................................................
F0P2G1_WEEVC/31-165                 ...............................emaalgiplaasg-------------DIG..ISEVFNPKKTHPDF..V.F.PWV---GA-..--TPV..KDVAAMPEEVVICLKK..VKGVHFDLL..VYNNFFI.VSEKLYEYMVINGFN.YE..NGKSIA.......H.ILDTKG.K...K.L..TE.EKFYLLRFY-..-----..---.----.-..------.......----.....................-----.--...---.-..-.---------.-.-.------------------------------------------wweitteevgiftsedess....................................................
A0A559JQA5_9BACL/71-281             ............................................MVKKSGKGVPMSLNAV..LAEEFNDNNPMPDM..N.Y.EWTISHGT-..-----..-EKVRFPEHLFLVCKE..-KILSFDFY..ADFDGYI.VSDDFLRIFLKYMLI.DD..YQMIPL.......E.TLSWKG.T...Q.I..TD.KKYHYLVPNK..KETWI..DYN.HSKY.D..VDEGKTk.....eQVISrdga.............fvrkFEEII.LK...ESE.V..D.KEVFVLKGS.L.L.TRFLFCSEIFKNEIEKEHLVGVDFIPIEELPAYYNKKYF---l......................................................................
A6EH29_9SPHI/24-222                 ...........................qirmfeneiqgdafsre----------------..-----------NTV..Q.Y.EWM-KAGF-..-----..-NDYQLKSELSLYSKH..-EYLDFDYY..RYANDFL.VSEDFLNAIAQYNID.--..YEKSAV.......R.VFSAVG.N..lE.L.kFR.KKYYFVKFRY..AEDVV..NFE.LSTF.E..DALSDKa.....ePIIHngvr.............yvknYENIV.LH...EDR.I..P.AEVFLIKDA.K.L.GYNLLCTGSVKLSPAVDGLKGVLFVPLEDFMDFKNN------ngs....................................................................
A0A917J3C7_9BACT/9-150              ............................................NRTQLPAGYPVKDDAV..FKPSFEAKNPKAVP..E.Q.KWTMFNHHK..MSFPP..TDAYQFPKEMYLVITK.kTAPIQFDYF.dCRQYVKL.VSGRFLKFIQEKGLTeEY..YEKAVL.......H.IADAKG.S...S.L..AG.DEYYAIRFGK.fDDKLF..EFP.AEGR.K..R-----.......----.....................-----.--...---.-..-.---------.-.-.------------------------------------------g......................................................................
Q7N9I7_PHOLL/22-223                 ............................................MNDYNSSLMPRYLHAI..VDTE-------NQI..N.E.KWD-YEGSR..HDIPY.yLLDKECPNTLYLLCNK.nIGKLWFNYY..QHNMAHI.LSDRFFDIINEFKLS.DH..VLKKLI.......A.TSIKDG.K...T.I..-N.NSLNYLFFTD..KELFL..NEK.YSIL.E..KDKYG-.......NLIP.....................-HKLS.FH...NES.L..N.YDIFSIRTT.L.L.AGFIFISEKVANRLIKENIKRIKLIKLDEVLNHYCVDFKYDI.......................................................................
A0A2S5CYB9_LYSSH/8-202              ..........................................fe---KEDKFCPILLEGI..LHTEFFEKNPFEAR..E.S.DAGEWRTT-..----K..NIMTDLPEELWFVSKD..-RNYSFDLR..WKRDGFF.VSIEFLNLLNKFEI-.GN..FHYTKL.......H.MVNKHK.E...S.I..TS.KEYYYVRFYN.rLEDVI..DMD.RSNI.EfyKQNGRM.......KKIW.....................--DLQ.LK...KSN.N..L.PDVFLINNS.K.L.LSILFCSEEFKKEAEKLNLNGITFVPSNEA------------dvf....................................................................
D1PUV2_9BACT/5-180                  .............................kwspnlpaneenifr----------------..--------------..-.-.---------..-----..----TMPQVLYLFINT.kRKEPTFDYL.yIQDGIWA.ISEFFLKYLREN-IG.SQ..IEAVPL.......K.VYNKNR.E...E.A..-Q.RVYYAMRVHA.fNDKLF..DFH.VESK.K..RTAGIK.......NYYL.....................YPDME.LK...ETN.E..K.QNIYTLREF.N.Y.REVLILNSVAKNWII-ENLYSPQIYKLSDFPYVLNNQYD---kka....................................................................
A0A173MDB7_9BACT/9-222              ............................................NRTQLPSGYPLKEDTV..LKSSYDAKSATKMP..D.Q.AWKTFNHHT..MSFPP..TGTHQFPEEMYLVVTK.kYPAIHFDYF.dYGYYVKL.VSGRFLSFMEEQGVTaDY..YEKALL.......H.IVDIQG.H...S.L..AN.QGYHALRFGK.fDDQLL..NWP.VETR.K..RAAGFK.......DFFL.....................YPNMQ.LK...APV.E..G.KGLFVLFEF.C.Y.NNTLVFTQQVKDVIL-TQFISPEIYKVADFPFVFNNQYKWDV.......................................................................
D3V9F1_XENNA/7-52                   ......................................vpylli----------------..--------------..-.-.---------..-----..----------------..---------..-------.---------------.--..------.......-.------.-...-.-..--.----------..-----..---.----.-..------.......----.....................-----.--...---.-..-.---------.-.-.--FLIFSESAVEKFLKMKISGVKIAPLDEAFKNYCLDYGYDI.......................................................................
A0A444GLV5_9FLAO/9-201              ....ektgkytpiglsegilhselnpkdpftplnsdsgdwrkli----------------..--------------..-.-.---------..-----..NSKVELPKELWFITRD..-KHYSFDLR..YDSGGFF.ISNHLLELFDKFNT-.GN..FTSTKL.......H.ILNKQL.Q...P.V..SD.KQYKYVKFYD..SEDMI..DYE.NSKI.D..FDKNGV......vKKI-.....................-WTLK.LK...GSE.V..K.NDIFMINSW.I.F.NRRLFCSDKFKEAALQGGVEGLQFISADDA------------gvf....................................................................
#=GC seq_cons                       ..............................................................................t....W..................p.phPpplalhhpc...thlpFDah...phphhI.lSccFLphhpphth..tt..aphstl.......p.llspcG.c...p.l..sp.cpYahl+hhp..tpshl..-ap.pu.h.t..pstht........phh......................h.cl..lp...ppt....p..slFhlpsh.h.h.tphlhho-phtpphh.tphhs.phhplp-h...................................................................................
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