#=GF ID Imm70
#=GF AC PF15601.13
#=GF DE Immunity protein 70
#=GF PI Imm42; Imm42_;
#=GF AU Zhang D;0000-0001-8535-7620
#=GF AU de Souza RF;0000-0002-5284-4630
#=GF AU Anantharaman V;0000-0001-8395-0009
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Finn RD;0000-0001-8626-2148
#=GF SE [1]
#=GF GA 27.00 27.00;
#=GF TC 27.60 28.40;
#=GF NC 26.50 24.20;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 90746521 --cpu 8 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 22731697
#=GF RT Polymorphic toxin systems: comprehensive characterization of
#=GF RT trafficking modes, processing, mechanisms of action, immunity
#=GF RT and ecology using comparative genomics.
#=GF RA Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL Biol Direct. 2012;7:18.
#=GF DR INTERPRO; IPR028185;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC A predicted immunity protein with an alpha+beta fold and
#=GF CC conserved tyrosine and tryptophan residues. Proteins containing
#=GF CC this domain are present in bacterial polymorphic toxin systems
#=GF CC as an immediate gene neighbour of the toxin gene, which usually
#=GF CC contains toxin domains of the Tox-REase-10 family [1].
#=GF SQ 77
#=GS A0A0M6WKN6_9FIRM/5-135 AC A0A0M6WKN6.1
#=GS A0A2T6EAR1_9GAMM/5-135 AC A0A2T6EAR1.1
#=GS A0A023DGT8_9BACL/5-135 AC A0A023DGT8.1
#=GS A0A1D9P2Y7_9FIRM/4-134 AC A0A1D9P2Y7.1
#=GS A0A414SZ19_9FIRM/5-135 AC A0A414SZ19.1
#=GS A0A2W6MUC0_9HELI/4-134 AC A0A2W6MUC0.1
#=GS V2YA42_9FIRM/3-148 AC V2YA42.1
#=GS A0A1H0XWV2_9BACI/5-135 AC A0A1H0XWV2.1
#=GS A0A0J1FQV1_9FIRM/57-186 AC A0A0J1FQV1.1
#=GS A0A7X9M1G1_9BACI/5-135 AC A0A7X9M1G1.1
#=GS A0A3S4UZB2_9ACTO/5-135 AC A0A3S4UZB2.1
#=GS A0A2N1J182_9BACT/6-50 AC A0A2N1J182.1
#=GS A0A224X2R2_9LACT/1-53 AC A0A224X2R2.1
#=GS G0L052_ZOBGA/5-135 AC G0L052.1
#=GS A0A1W1VV51_9FIRM/7-88 AC A0A1W1VV51.1
#=GS F2NX85_TRES6/5-135 AC F2NX85.1
#=GS A0A1N6N766_9GAMM/21-151 AC A0A1N6N766.1
#=GS A0A0Q3W3B2_9BACI/5-135 AC A0A0Q3W3B2.1
#=GS D2MPW2_9FIRM/4-134 AC D2MPW2.1
#=GS A0A918UAD9_9NEIS/5-135 AC A0A918UAD9.1
#=GS A0A073JVN7_9BACI/5-134 AC A0A073JVN7.1
#=GS A0A7I9VK98_9BACT/3-135 AC A0A7I9VK98.1
#=GS A0A2N5G8F8_9BACI/5-135 AC A0A2N5G8F8.1
#=GS A0A845RGE2_9FIRM/3-148 AC A0A845RGE2.1
#=GS A0A918P5P1_9NEIS/5-135 AC A0A918P5P1.1
#=GS A0A6M8MK60_9PSED/6-93 AC A0A6M8MK60.1
#=GS A0A3A9SV65_9FIRM/5-135 AC A0A3A9SV65.1
#=GS A0A2U3CRI9_SULT2/5-135 AC A0A2U3CRI9.1
#=GS A0AA95MIM7_9BACI/5-135 AC A0AA95MIM7.1
#=GS A0A8J6PRC7_9HYPH/5-135 AC A0A8J6PRC7.1
#=GS A0A4S2DF62_9CLOT/5-135 AC A0A4S2DF62.1
#=GS A0A1H9U3C4_9LACT/5-132 AC A0A1H9U3C4.1
#=GS A0A224X2Q4_9LACT/2-45 AC A0A224X2Q4.1
#=GS A0A4Z1BZY5_9GAMM/5-135 AC A0A4Z1BZY5.1
#=GS V1CFD5_9FIRM/1-125 AC V1CFD5.1
#=GS Q5WBC9_SHOC1/5-135 AC Q5WBC9.1
#=GS D7V0H5_LISGR/1-58 AC D7V0H5.1
#=GS B9XKD2_PEDPL/3-136 AC B9XKD2.1
#=GS G2LF64_CHLTF/6-136 AC G2LF64.1
#=GS F9ZVR4_METMM/3-136 AC F9ZVR4.1
#=GS S6A8H2_9SPIR/1-116 AC S6A8H2.1
#=GS A0A975H0C5_9BACL/5-135 AC A0A975H0C5.1
#=GS A0A7T7MBJ1_9ACTO/1-72 AC A0A7T7MBJ1.1
#=GS A0A1H9D853_9FIRM/5-135 AC A0A1H9D853.1
#=GS A0A345ZHJ8_9GAMM/1-93 AC A0A345ZHJ8.1
#=GS A0A165WQ48_9BACI/5-135 AC A0A165WQ48.1
#=GS A0A0D5NKB5_9BACL/4-134 AC A0A0D5NKB5.1
#=GS A0A8J3VJE2_9ACTN/3-139 AC A0A8J3VJE2.1
#=GS A0A1M6QFG6_9CLOT/5-135 AC A0A1M6QFG6.1
#=GS A0A4Z1B907_9GAMM/5-135 AC A0A4Z1B907.1
#=GS A0A1W1VTZ9_9FIRM/5-129 AC A0A1W1VTZ9.1
#=GS A0A7W0BV28_9BACL/5-135 AC A0A7W0BV28.1
#=GS A0A3R6N9F0_9CLOT/4-134 AC A0A3R6N9F0.1
#=GS A0A142WV81_9PLAN/3-136 AC A0A142WV81.1
#=GS H8MHD1_CORCM/5-133 AC H8MHD1.1
#=GS A0A7K3Y192_9ACTN/5-133 AC A0A7K3Y192.1
#=GS E3GHW3_9FIRM/4-134 AC E3GHW3.1
#=GS A0A372EDR5_9BURK/5-112 AC A0A372EDR5.1
#=GS A0A416NFP7_9FIRM/5-135 AC A0A416NFP7.1
#=GS W7LAF8_CYTFI/5-135 AC W7LAF8.1
#=GS A0A0A8JEU0_BACSX/5-135 AC A0A0A8JEU0.1
#=GS A0A7V9Z8I9_9BACL/5-135 AC A0A7V9Z8I9.1
#=GS A0A0A5GGS8_9BACI/5-135 AC A0A0A5GGS8.1
#=GS A0A263D6Q0_9PSEU/5-135 AC A0A263D6Q0.1
#=GS A0A4Y8IFW3_9BACI/5-135 AC A0A4Y8IFW3.1
#=GS A0A7X6S0S6_9STRE/5-135 AC A0A7X6S0S6.1
#=GS G8LVN5_ACECE/5-135 AC G8LVN5.1
#=GS A0A167TE60_9BACL/5-135 AC A0A167TE60.1
#=GS A0A075KCH8_9FIRM/5-135 AC A0A075KCH8.1
#=GS A0A3M8SVA5_9GAMM/22-153 AC A0A3M8SVA5.1
#=GS V7IE72_EIKCO/5-135 AC V7IE72.1
#=GS A0A2T5MCT3_9GAMM/5-135 AC A0A2T5MCT3.1
#=GS A0A3A8WRI0_UNCXX/5-135 AC A0A3A8WRI0.1
#=GS A0AAN0YST0_PARTM/5-135 AC A0AAN0YST0.1
#=GS A0A1M5USA4_9FIRM/5-135 AC A0A1M5USA4.1
#=GS A0A3S3Q5F2_9FLAO/4-134 AC A0A3S3Q5F2.1
#=GS I8J6M5_9BACI/5-135 AC I8J6M5.1
A0A0M6WKN6_9FIRM/5-135 ........FKVAFFYY..........QIGHGDFLHSFFSTVSYNLENG...........KWGSRFPTIMNEL.YQGTLDKDNVETAIEELKKIQLELQAFSPDKVVWDIDDLSNQPPWGKNISNDI....TNLSNYFVTSDGEDFITI.FFNALEKAKKMQIDLTI..............................................
A0A2T6EAR1_9GAMM/5-135 ........LKIGSINT..........EIGSADFLHAFFSTVSYRLESD...........GWGSRFPVIMNEL.FQGQLDAAHVDAAIVELDSIQEELKSFKPKDVIWDIYNLDAKPPWGDNISARI....TDLSNYFVTSNGSDLIEV.MRDRFNRLKLKGTFLEI..............................................
A0A023DGT8_9BACL/5-135 ........FKVKYYWY..........PIGHGDFLHSFFSTVSYHLEPN...........GWGTKYPLLLNKL.YNGKLEYKYIKDAIKEIDEIQESLKNYSPSQVIWDIEDLSKTPPWGDNISDEI....TDLSNYFVTSDGEDLITI.LKKALNKALKVKSDIEI..............................................
A0A1D9P2Y7_9FIRM/4-134 ........FTVKYYWY..........QVGTGDFLHSFFSTIAHNIENG...........VWGTRFPVIMKEL.YSGKVSVEHLDEALQEVRTITEELRKCSVDKAIWDIDDLSIPMPWGDNISPDI....TDLSNYFVTSDGEDLITI.LSHAIEKAMELKTDLRI..............................................
A0A414SZ19_9FIRM/5-135 ........FKVGYYWF..........QVGTSDFLHSFFSTICIRLEHG...........KWGRVYPKLMGEL.YQGCLKNQDLNEGLEELRKVRKELKNFSPSDVIWDAEDLSLTPPWGNNISSDI....TDLSNYFVTSDGRDLISV.LSEAMNEAKEMQCDIEI..............................................
A0A2W6MUC0_9HELI/4-134 ........FSINDFWY..........EIGSGDFLHAFFSNVAYHLEKG...........NRGSRFPILMNEV.YQGKLNFSKASLALNELENIQKEFKNFTPKQIIWDIENLSLMPPWGDNISSDI....TDLSNYFVTSNGNDFIEL.FKKVLQLADNEKANLTI..............................................
V2YA42_9FIRM/3-148 .......l-YLCIFDEagdd..icgvEVGLYQYFGDFRATVDQYTNKGlislfvkpgrkIFSSPMSTLLNHSdCDGSWSVQDCKLLKTELEEIKQVFLEEPPSAKIIA---------SKQDIFRLFgitpKNLFECFVDSDCEFLIDR.LIELCDLAMEKNRPIMF..............................................
A0A1H0XWV2_9BACI/5-135 .......i-NVGDFYY..........EIGSGDFFHSFFSTISYHLEPE...........GWGTKYPFLMNEF.YQGSLKWDLSTKVIEELKDAHRRLQNYKPSQVVWDIEDTSLQPPWGDNISSDI....TSLANYFVTSDGEDLIEV.LYNAFQTSYNEKENIEI..............................................
A0A0J1FQV1_9FIRM/57-186 ........FKIDFLSY..........QAKHRDLFHSFCSTISYYLEPR...........GWGTEFPYLLIHF.YNGKLDWVDVPKLIGELKDIRERLKYIETTDIILDIEDLSERGSLRKRECSNY....SNLANCFLVNDGRNLFDV.LLKTLENSLIE------tdkei.........................................
A0A7X9M1G1_9BACI/5-135 ......il--VDCFYY..........ELSQSDFVHSFFSTISYHLEKE...........GWGTKYPLLMNEL.YNDKLNWNEVSVVKANLIEIEQELSKYLPEQVIWDIDDLSKNPPWGDKISSKV....TNLANYFATNDGKTFFEV.LRTAIDVAEEDKCYLKI..............................................
A0A3S4UZB2_9ACTO/5-135 .......l-NTDGYWF..........TIGSGDFFNSFFSTVVVNLESG...........RWGSRFPMIMNGL.YRGKVEANDVEPTLVELAQIREEFRALPPTSVVWDFEDRSKQPPWGDDVADNI....TDLSNYFVTSNGEDLFEV.IEEGLQKAKQYGWPIEV..............................................
A0A2N1J182_9BACT/6-50 ........FKIYSDWI..........EFGYSETLYSFFSTICYRLENS...........KWGSRFPILMN--.-----------------------------------------------------....------------------.-----------------cyii..........................................
A0A224X2R2_9LACT/1-53 ........--------..........----------------------...........---------MNEL.YSGSLSLDKLKDAKNELEEIKQEFSKLSPDKIVWDAEDLGKTLPWGGEI----....------------------.-----------------..............................................
G0L052_ZOBGA/5-135 .......l-RTGSFSY..........EVGRSDFLASFFDTIEIRLTKG...........LFGKKYPTVLNEF.YNGNLKYENLERAEKELIDIQKRLKKHKPSKVVWDKFDLNKMPPWGGNISSHI....TDLSNYFVTSDGKDLFKV.IFQAIETAKSEKSGITI..............................................
A0A1W1VV51_9FIRM/7-88 vhaagisv--------..........VLGTYAYCDAFREVICGRSEDG...........TRRSSFPRL-EKF.FSGECSARDAEGLLQELEVIKAEFQSVMH------------------------....------------------.-----------------pvalycakdge...................................
F2NX85_TRES6/5-135 ........LKVKFNWY..........QIGESELLYSFFSTIAYNLENN...........IWGSKFPTIMIDL.YQGKVDVDKLQFVEQELQTIRNELSLLPVNKLIWNIDDLSKMPPWGTNISKDI....RNLSDYYVTSDGNNLLDV.LFKAINKAKELKSYLEI..............................................
A0A1N6N766_9GAMM/21-151 ........IKVGSITD..........EIGTSEFFHAFFSTVSANLESE...........GWATRFPILLGKL.YQGDLESGLANQAISELTQIRKELSGFEPGRVVWDIENPAKQPPWGNEISSEI....TSLANYFVTSTGRDLIST.LIEALEDAAEKGKPADI..............................................
A0A0Q3W3B2_9BACI/5-135 ........FKVKYYWY..........QVGHGDFLHSFFSTINYHLERN...........GWGTEYPFLLNEL.YNGKLENENIDSAITELEVIKKKLQSYSPSQVIWDIEDLSKRPPWGDNISKDI....TNLSNYFITSEGEDLIDM.LMKALEKGLKTNSDVYI..............................................
D2MPW2_9FIRM/4-134 ........FRVGNISY..........EIGAASFLYSFFSTVAYRLEKG...........RWGSRFPMIMNEL.YQGQLSLEKILVAKQELKQIKKELSLFLPDQVVWDIDDLSKQPPWKNHISHTI....TSLENYFITCDGQDFIEV.FQNTLDTAIEIKEDVLI..............................................
A0A918UAD9_9NEIS/5-135 ........LKLGSITD..........EIGSDDFFHSFFSTISGNLESA...........GWGSRFPVLLNKL.YQGELSQEWAADALDELEAIRKMFSELPVTDVIWDLEDRKKTPPWGDVISNDI....TDLSNYFVTSTGRPLFSV.IRECLEELRDSGGVL--kv............................................
A0A073JVN7_9BACI/5-134 ........FSVDIFFY..........EAGHPDFLHSFFSTISYHTEPE...........GWGTKYPLLMQDL.YFKKLNWKDAPEALRNVEEIRGVLNKLSPSEVVWDIENVSKQPPWKDKIPNKI....TSLANYHMI-QGTIFLDL.LKHALEKSAEYKVDVII..............................................
A0A7I9VK98_9BACT/3-135 .lylcvfr-------Ddee...lfgiDVGSYDDWERFRGEA--RARDG...........RIFRRYGALRVHVsPTTHWSPRDAARLAGELAHLREALRREPPRPLPPG--------SWQAELAAERglapATLADCFFDVDGVPLFDG.LAELCRLAVETRQPIL-f.............................................
A0A2N5G8F8_9BACI/5-135 .......l-LVDCFYY..........ELGHSDFVHSFFSTISYHLEKE...........GWGTKYPLLMNEL.YNDKLNWVDVSVAKSNLIEIEQELSKYSPERVVWDIDDLSKKPPWGDKISPKV....TSLADYFATANGKTFFEV.ICNTMDVAEEDKCDIKI..............................................
A0A845RGE2_9FIRM/3-148 .......l-YLCIFDQygee..icgvEVGLYRYFQELRDTVARFTPKGpiarlihpgsgRLSSKMPTLLVHSdCNGSWSVSECRELKQELEEIKQVFIQEPVSPETVA---------LKQDIFKFYgvtpQNLFECFIDSDCEFLIDR.LLDLCDCAIEKKRPIMF..............................................
A0A918P5P1_9NEIS/5-135 .......i-KLGSIID..........EIGSDDFFHSFFSTISGNLESA...........GWGSRFPVLLNKL.YQGELSQEWAADALDELEAIRKMFSELPVTDVIWDLEDRKKTPPWGDVISNDI....TDLSNYFVTSTGRQLFSV.IRECLEELRDSGGVL--kv............................................
A0A6M8MK60_9PSED/6-93 .vlaemti-------D..........VLGPASDVDCFFKSVVFFLEDG...........QRGSKYPSVTEKL.YCRSLGKNELAELKVDLENVRAEFNGIIAD-----------------------....------------------.-----------------sfnisafgvdekntr...............................
A0A3A9SV65_9FIRM/5-135 ........FTVKFYWF..........QVGTGDFLHSFFSTIAYNLEDK...........NWGSKFPTIMNEL.YSGELKYENIHNAINELDEIRHELSRFSPDKVVWDIEDLSKQPPWEDNISDDI....TDLSNYFVTSDGEDLIEV.LKRALETGIEKKESVKI..............................................
A0A2U3CRI9_SULT2/5-135 ........FLVDCFYY..........EVGQPDFLHSFFSSVSYNLEKN...........GWGSRFPKLLKQL.YHDRLPYTDVPLAIEEVRVIQEELSKLSPDKVIWDIEDLTKLPPWGTDISPMV....TNLENYFATPGGETFTEL.LLTALSVAEVERQDLVI..............................................
A0AA95MIM7_9BACI/5-135 ........FQFDCFFY..........QVGHGDFLHSFFSTISYHLEPD...........GWGTKYPKLLKDL.YYKKLKYMDIPKAIKETEEIRAKLVNFSPSQVVWDIDDLTAQPPWGNRVSEQI....TNLSQYFKTSDGRDLFDL.LLISLNGAYDDKFDLEI..............................................
A0A8J6PRC7_9HYPH/5-135 ........LKIGATID..........EIGSSEFLFAFFSTISANLEKK...........GWGTRFPVLLNEL.YSGELPSQRAGTALEELRTVRSELSAIPPDRVVWNYEDRTKGPPWGHDISSDI....TNMSNYFVTSGGRDLFDV.LEEALEYQKGRG-----gvaki.........................................
A0A4S2DF62_9CLOT/5-135 ........FKIDFLWY..........QVRTPDFLHAFFSTISYNLEEN...........KWGSKYPILMNEL.YQGKLNWENASKAVEELKLIKEELKKINPEYVVWDIEDISKQPPWVKNISPDI....TDLSNYFITSDGRDLISV.ILMALNDSICEKTDVEI..............................................
A0A1H9U3C4_9LACT/5-132 ........IKVDFLWY..........SIGTGEFFNSFFSTVYVNLENK...........KWGSRFPLIMKNL.YSGTLDIDELNIAKNELSEIKQELFKLAPNKIIWDAKNLQKSPPWGSNISQDI....KTLADYFVTSDGENLFSV.LDDALNRPYTKK-----cn............................................
A0A224X2Q4_9LACT/2-45 .......g--------..........----------------------...........-------------.---------------------------------------------GRNISSDI....TNLAEYFITSDGNNLIDR.LNKAIDEGLKEQVSIEI..............................................
A0A4Z1BZY5_9GAMM/5-135 .......i-TVGPITA..........EIGTGSFVHAFFSTVSVHCEPN...........GWGTRYPRLMNHL.YQGYLSHSQAAEALEELQDAHAVLDKVSPSKVVWDVEDLSAQPPWGTNISSDI....TSLGNYFVSSTGRDLFAL.LKEILQLSIDRQKDA--tl............................................
V1CFD5_9FIRM/1-125 .......m-------Y..........EIGTSSFLHCFFSTVAYRLEND...........RWGSKFPKVMNEL.YQGKLSWKNAFVAKRELEQIREGLDELLPDKVIWDIGDLSEQPPWGNNISNTI....TSLGNYFVTSDGRDFIEV.FNSALDTAMEIKEDVLI..............................................
Q5WBC9_SHOC1/5-135 ......il--VDCFYY..........ELGHSDFVHSFFSTISYHLEKE...........GWGTKYPLIMNEL.YNDKLNWNDVSVVKANLIEIEKELSKHTPEQVIWDIDDLSQKPPWGDKISPKV....TSLANYFATADGKTFFEV.LRTAIDVAEEDKCDLKI..............................................
D7V0H5_LISGR/1-58 .......m--------..........----------------------...........-------------.-------------------------KFPPKEIIWDVEDLEKNPPCGTHISKDI....TSLAQYFVIADGKNLISV.LEEDVD-----------ieikv.........................................
B9XKD2_PEDPL/3-136 .......l-YLCVFDEdde...idglDVGAYSDFAHFRNTIAQELEEG...........RPGTRFPTLMLHSdCDGEWKPDECLKLSRELEIIASELKQRPPREFHSE---------WQKGVVKKLgltpLNLYDCFIDVDGEPILER.LARLVETAKRRQLPIL-f.............................................
G2LF64_CHLTF/6-136 ........LWVDTKRY..........EVGSPSFFHCFFSTIAYRLEND...........AWGSVYPRIMLDF.YKGRLRYTDAPEALSELDAIQLGFEMMPPEDIIWDYDDLDRQPPWAEGALENT....SCAAECFFTPTEEHLFAV.LRQAFNRSIEVRHDVRI..............................................
F9ZVR4_METMM/3-136 .......l-YLCVFDGdee...vdgvEVGPYADFNELRNYIIHELELG...........QAGIKFPTFINHSdSDGEWSVADCVKLNAELSEIVLMMKTKPPVPFVSE---------WQSSIAKSTglvpKTAYESFIDVDGELVLKR.IGHLVDVALQYGLPIL-f.............................................
S6A8H2_9SPIR/1-116 ........--------..........-------MHCFFSNIAYHLENG...........QWGDRFPYLMEHL.YNGLLEKQYVKNAIKELHTVKKEFVHIPSQKVIWDIEDLSQQPPWGNDISEDI....TDLSNYFVTSEGEDLFDV.LFEVLDVAKDDNENVE-l.............................................
A0A975H0C5_9BACL/5-135 ........FKVKYYWY..........QVGHGDFLHSFFSTISYHLEQN...........GWGTEYPFLLNEL.YNGKLENKNIDSAITELEAIKKKLQKFSPSQVIWDIDDLSKRPPWGDNISNDI....TNLSNYFVTSEGEDLINM.LMKALEKGKKTNSDVYI..............................................
A0A7T7MBJ1_9ACTO/1-72 ......mg--------..........----------------------...........-------------.------------------EVDQGLAGLAASKVVWGIEGLSVPPPWGSSISPEI....TGLSSCFVASGGEDFILR.LRHALEQALAAGSDLTV..............................................
A0A1H9D853_9FIRM/5-135 .......f-VVGDEYY..........SVGSGDFLHSFFSTVAYNLENG...........DWGIKYPYIMNEL.YRGELEVESAKECLAELEIIRTELKKYLPDKVVWDIDDLSKRPPWGDNISADI....TDLSNYFVTNDGEDFIEV.LKDALEKALELNEKLLI..............................................
A0A345ZHJ8_9GAMM/1-93 ........--------..........----------------------...........---------MGNL.YQGFLPSDESRAALDELHTIDRELTALPVSRVVWDIEKPHLPPSPHYTLGANA....QNAAEFFVTINGQNLLRGgLIWSVESAVEFGHAVEI..............................................
A0A165WQ48_9BACI/5-135 ........LKVKYYWY..........PIGHGDFLHSFFSTVSYHLEPN...........GWGTKYPLLLNKL.YNGKLEYKYIKDVIKEIDEIQESLKNYSPSQVVWDIEDLSKTPPWGDNISDEI....TDLSNYFVTSDGEDLITI.LQKALNKALKIKSDIEI..............................................
A0A0D5NKB5_9BACL/4-134 .......l-SASYFWF..........PVGTGNFLHAFFSTISYNLEPN...........GWGTKYPFLMKRL.YSGNLENKFVPALLEEVKEIRNLLEAIPPSKVIWDIEDLSKQPPWGNDISPEI....TSLANYFANNRGEDLFEL.FKRAIQTAIDYDLDLKI..............................................
A0A8J3VJE2_9ACTN/3-139 ....lylc----VFTSnevddeidgiEVGSYEDFGRLRDVVAQRLEPD...........GWGSRFPVLMGHPdSDGQWTPEESVALAAELTVIAAELEQLPPIELPKG---------WQAETAAKFgvvpQTLRDCFIDVDAESLLDR.LTELARLSARERQPIWF..............................................
A0A1M6QFG6_9CLOT/5-135 ......lf--YSEIWW..........EIGSPDLLHSLFSTISYNLEQN...........GWGSKYPYLLKKL.YNSKIERGETEMALNEIMDIKEKFLSLSAQNMIWDIEETTKKVPLNYNYHLKA....QNLAECFISVGEKNIIEK.LIETLEWCTKKNFTLEI..............................................
A0A4Z1B907_9GAMM/5-135 .......i-TVGPITA..........EIGAASFVHAFFSTVSVHCEPN...........GWGTRYPHLMNHL.YQGYLSHSQAAEALEELQDAHAVLDKVSPSKVVWDVEDRSAQPPWGTNISSDI....TSLGNYFVSSTGRDLFAL.LEEILKLSIDRQKDA--tl............................................
A0A1W1VTZ9_9FIRM/5-129 ..ayvdaa----DLFV..........KIGSYGWYHSFRSTVCDKLEDG...........DWGSRFPLLQNHSdCDGDYSPEEAVELLEELRTIRKEFEGVMYPVVL--------------------....------------------.-----------------ycdgqgsvldyrekyseagifiygngfgfgvteeglvvqsedptrv
A0A7W0BV28_9BACL/5-135 ........FLVDCFFY..........EVGHPDFLHSFFSTISFHLEEE...........GWGTKYPLLMNDL.YNDKLKWHDVPKARNQLKEIEEQLSKYSPEQVVWDIDDLSKVPPWGDKISSKV....TNLANYFATSEGKTFFEV.LYNAMDVAEEDKSDIKI..............................................
A0A3R6N9F0_9CLOT/4-134 ........FKVEYNWY..........EIGSSDFLYAFFSTVAYNLENK...........KWEIRFPIIMKRL.YLGKLETTDISSAIIELKMIQQGLRKFKPDKIIWDYENPKKQPPWGKNISPDI....IDLANYFVTSDGEDFLTI.FLHAPEKAKELNSAIEI..............................................
A0A142WV81_9PLAN/3-136 ........LYLCVFDDgde...legvEVGSYADFGFFRDSVTELLEGG...........KTGDKYPTLILHSdCDGEWTLAECERLKGELEDISAKFRDLPAIQYQSD---------WQRHVAHFLglkpTCLYDSFIDVDGEPVLER.LSRLCSVAIQSGQSIVF..............................................
H8MHD1_CORCM/5-133 .......l-MIDNVAT..........ELGRGDFVHAFFSTLSARLEPE...........GWGTRFPTLLNTL.YQGELPKAHAARAVEELRAARMELRAFSPAEVVWDIEDRDARPPWGADIASSI....TSLADYFVTSTGRDLFDA.MIEDLEFLRDQG-----hgp...........................................
A0A7K3Y192_9ACTN/5-133 ...tekad-----RIV..........NVGSAGNLYSLYSTAATLMGQR...........--AKKVALGLAFL.EHGSCASKDCAKTLKQLSEIKIVLEKHAPTEAVWDMEHPNILAPWNGHLSPDI....SSCADLYTTSEGELLIGE.LVSLLQFAGSSKQSVVV..............................................
E3GHW3_9FIRM/4-134 ........FKVKYYWF..........QIGSEDFLFSFFSTVAYNLENK...........KWGTKFPVIMNEL.YLGELNSSRIPEAINELEQMKQGLAKYSPNKVIWNIKNLSAQPPWGTNISDDI....TDLSNYFVTSDGEDFITI.FNHALLKAEELNCALKI..............................................
A0A372EDR5_9BURK/5-112 .......i-RVGSVTS..........EIGTPSFLNAFFSTISVRCEPD...........GWGSRFPLLMNDL.YQGRLSHKNARAALAELTAVKQLLEGFPPSAVVWDIDDLSARPPWGDEIAEEI....TSLGNFVVPS--------.-----------------ns............................................
A0A416NFP7_9FIRM/5-135 ........FKVKFYWY..........QIGRGDFLHSFFSTVAYNLENG...........NWGSRFPVIMNEL.YQGKIECDNIGKAIQELSIIRKELKKFSPDRVVWDIEDLSKQPPWGNDISKDI....TDLSNYFVTSDGNDFLIV.FEHALEKAKEVNAEMLI..............................................
W7LAF8_CYTFI/5-135 ........FKVKYYWY..........QVGHGDFLHSFFSTISYHLEQN...........GWGTEYPFLLNEL.YNGKLENKNIDSAINELEAIKKKLQKFSPSQVIWDIEDLSKRPPWGDNISKDI....TNLSNYFITSEGEDLIDM.LMKALEKGQKTNSDVYI..............................................
A0A0A8JEU0_BACSX/5-135 ........FKVKFYWY..........QVGHGDFLHSFFSTISYHLEQN...........GWGTEYPFLLNEL.YNGKLENKNIESAINELEEIRKKLQEFSPSQVIWDIEDLSKQPPWGDNISNDI....TNLSNYFVTSDGEDLIDI.LMKALEKGQKTNSDIYI..............................................
A0A7V9Z8I9_9BACL/5-135 ........LKVKYYWY..........PIGHGDFLHSFFSTVSYHLEPN...........GWGTKYPLLLNKL.YNGKLEYKYIKDVIKEIDEIQESLKNYSPSQVVWDIEDLSKTPPWGDNISDEI....TDLSNYFVTSDGEDLITI.LKKALNKALKIKSDIEI..............................................
A0A0A5GGS8_9BACI/5-135 ........FKIDFLWY..........QVGHGDFLHSFFSTISYHLEPN...........GWGSEYPYLMNEL.YQGKLSWKDVPKALTEVGEVRSKLKSFTPDKVIWDIEDTSKQPPWGQNISSTI....TSLANYFVTSDGRDMFEV.LVMALKDAEYEKVDIEI..............................................
A0A263D6Q0_9PSEU/5-135 ....lhah----DESA..........ELGSASFVHAFFSTAAVRLEYS...........RWGSRFPAVMDSL.YQGTLPADQVAQARRELRVVRAELGDFEPRHVVWDIEDRTAKPPWGDEVSPDV....TSLGDYFITSDGEDLFEV.MDDLLAHAEEHGTDVRI..............................................
A0A4Y8IFW3_9BACI/5-135 ........FQVDFNIY..........RIGHGDFLHSFFSTISYHLESD...........GWGAKYPLLLNEL.YFRGINSKDISNAIQEVEEVKEGLKTLPPSEVVWDIEDLDKVPPWGNDISQEI....TNLSNYFVTSDGRDLFDL.LLLALNDAIELESNIEI..............................................
A0A7X6S0S6_9STRE/5-135 ........FEVDCFYY..........TIGTADFLNSFFSTVFVKLECS...........RWGSRFPILMNDL.YQGVLPKESVYKAQEELATIKKELELLPPSEIVWDFDDLSLTPPWGDNISPEI....RTMADYFVTSEGENLLSV.LDEALRKAVTLNEAVTI..............................................
G8LVN5_ACECE/5-135 ........FRYSAIWR..........EFGDADLLHAFFSTISYRLESN...........NWGSIYPYLQKNF.YNDGLNSDETIKALDELKDIREKFAKLKPEDIIWDAEDLTKKPPNSFFDQLQP....SNLSECFVALNGKNIFDI.LTEVFEFCSKKGLSVKI..............................................
A0A167TE60_9BACL/5-135 ......il--VDCFFY..........ELGHSDFVHSFFSTISYHLEKE...........GWGTKYPLLMNDL.YYDKLNWENISVARTNLIEIEQELSTYSPESVIWDIDDISQKPPWGDKFSSKV....TNLANYFATTDGKTFFEV.IRTAMDVAEEDKCDMKI..............................................
A0A075KCH8_9FIRM/5-135 ........FKIDFLRY..........EIGHGDFLHSFFSTISYHLEPE...........GWGTKYPYLLNHL.YNGKLCVTDVAKAVTELEEVRSKLTHFSPNEVIWDIENLNKKPPWGTNISGDI....TNLSNYFVTSDGRDLFDV.IFVTFKDSQDLKVNIEI..............................................
A0A3M8SVA5_9GAMM/22-153 ......ir--TGSVVT..........EVGSGAILHAFFSTISSNLEQA...........GWGTRFPTTMNKL.YQGSIAPTDSSAALNELLVIEKELLKIPTSNVVWDIENPAARPSPYYKPGRGA....TNAVDYFVTVNGLNLLRAgFIESVESALEFGDEVRI..............................................
V7IE72_EIKCO/5-135 ........LKVDFFWW..........PIGDGDFFYSFFSTVCVNIEHS...........EWGSKFPVLMKDL.YQGCIVYEKLEQAIEEITKVEEELAKLPPKQVVWSFEDRAKMPPWGDNISPDI....NNLSDYFVTTDGRNLITV.LKDAFDKAGAEQVNVEV..............................................
A0A2T5MCT3_9GAMM/5-135 ........LNVDNIVT..........EVGAPSFFHAFFSTISVRLEPN...........GWGSRFPVLLKSL.YAGRLPATQIESGIVELRLARKELKKFRPEDIVWDIENRNARPPWGSSISPAV....TDPSNYFVTSHGNDLFQV.LEEVLDFAASEKKDVL-v.............................................
A0A3A8WRI0_UNCXX/5-135 ........FSVEVDWF..........QIGNGDFLYSFFSTVAYHLENE...........NWGSRFPFVMNEL.YQGRLEAENVGRAISEVVKIRSELKNYPPDQVIWDIDNLSAKPPWGDNISGEI....TDLSNYFVTSGGEDFFSV.FLEALEDAKELGVSVKI..............................................
A0AAN0YST0_PARTM/5-135 ........FKVKYYWY..........PIGHGDFLHSFFSTVSYHLEPN...........GWGTKYPLLLNKL.YNGKLEYKYIKDAIKEIDEIQESLKNYSPSQVIWDIEDLSKTPPWGDNISDEI....TDLSNYFVTSDGEDLITI.LKKALNKALKVKSDIEI..............................................
A0A1M5USA4_9FIRM/5-135 ........LRVWTIWY..........EVGTADFFYSFLSTVSYRLESD...........GWGSKYPIIMQSL.YDGKLEYEHVPAAAAELTNIQAALTKLAPSDVVWDIEDLSKQPPWGDKISKSI....TSLANYFVTSDGKDLIKV.IFNAFDRARELKTDVYI..............................................
A0A3S3Q5F2_9FLAO/4-134 ........LKVGPIFY..........KVGTGDLLHSFFSSIAYNLEDN...........KWGAKFPFIMKEL.YAKELSVEDIPQAVKEINLIRETFKDYAPNCVIWDIENLEKRPPWGDDIAAHI....TSLSNYFHTSEGQDLFET.FLKALETAAIIKKVLKI..............................................
I8J6M5_9BACI/5-135 ........FKVKHYWY..........QVGHGDFLHSFFSTISYHLEQN...........GWGTEYPFILNEL.YNGKLNYKNIDRAITELELIKKKLQKYNPSQVIWDIEDLSKRPPWGNNISKDI....SNLSDYFITSEGEDLIDT.LMKAFKKGLKTNSDVFI..............................................
#=GC seq_cons .........plt.hhh..........plGpu-FlHuFFSTluhpLEps...........sWGo+aPhLhscL.YpGcLshpphtpAlpELcpI+pcLpphsPspVlWDI-DlstpPPWGssISscI....TsLuNYFlTS-GcsLhpl.Lhcslcpuhchppsl.I..............................................
//
