GenomeNet

Database: Pfam
Entry: K-cyclin_vir_C
LinkDB: K-cyclin_vir_C
Original site: K-cyclin_vir_C 
#=GF ID   K-cyclin_vir_C
#=GF AC   PF09080.12
#=GF DE   K cyclin, C terminal
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1g3n
#=GF GA   25.30 25.30;
#=GF TC   25.60 25.80;
#=GF NC   24.90 25.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Cyclin
#=GF CL   CL0065
#=GF RN   [1]
#=GF RM   11124804
#=GF RT   Structural basis of inhibition of CDK-cyclin complexes by INK4
#=GF RT   inhibitors. 
#=GF RA   Jeffrey PD, Tong L, Pavletich NP; 
#=GF RL   Genes Dev. 2000;14:3115-3125.
#=GF DR   INTERPRO; IPR015164;
#=GF DR   SCOP; 1g3n; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Members of this family adopt a secondary structure consisting of
#=GF CC   a five alpha-helix cyclin fold. Interaction with cyclin
#=GF CC   dependent kinases (CDKs) at a PSTAIRE sequence motif within the
#=GF CC   catalytic cleft of CDK results in the regulation of CDK activity
#=GF CC   [1].
#=GF SQ   6
#=GS U5NJ04_9GAMA/147-252      AC U5NJ04.1
#=GS Q9J2H1_9GAMA/148-246      AC Q9J2H1.1
#=GS Q53CR8_9GAMA/148-246      AC Q53CR8.1
#=GS A0A0B5CYI2_9GAMA/148-246  AC A0A0B5CYI2.1
#=GS F5HC81_HHV8/148-253       AC F5HC81.1
#=GS VCYCL_HHV8P/148-253       AC Q77Q36.1
U5NJ04_9GAMA/147-252                 AIVATDVTACLLYRLDPVPDQYSAWHRATNSLIDRALVDPRAGTLRASVLSAACCALAASTLETPSGLTSDEILQRLAAILSREVVELKGARELVTSIL-----.--atvtldi
Q9J2H1_9GAMA/148-246                 AVLPTDAIGPTLFKSGFTKEQLFALHSQVVESVHKAIVNPATGGLPPSLVAAA-CALFSLGAAAPPPA-------RLAEAVGVSAATLAAAAESVATTLREFDEdRI.......
Q53CR8_9GAMA/148-246                 AVLPTDAIGPALFKSGFTKEQLFALHSRVVESVHKAIVNPVTGGLSPSLVAAA-CALFSLGAAAPPLD-------KLAEAIGVSAATLTAAAESVATTLRELDEdRI.......
A0A0B5CYI2_9GAMA/148-246             AVLPTDAIGPALFKSGFTKEQVFALHSQVVESVHKAIVNPATGELSPSLVAAA-CALFSLGAAAPPPA-------SLAKAIGVSAEALTAAAESVSATLLEFDEdRI.......
F5HC81_HHV8/148-253                  AVLATDVTSFLLLKLLGGSQHLDFWHHEVNTLITKALVDPKTGSLPASIISAAGCALLVPANVIPQDTHSGGVVPQLASILGCDVSVLQAAVEQILTSVSDFDL.RI.......
VCYCL_HHV8P/148-253                  AVLATDVTSFLLLKLLGGSQHLDFWHHEVNTLITKALVDPKTGSLPASIISAAGCALLVPANVIPQDTHSGGVVPQLASILGCDVSVLQAAVEQILTSVSDFDL.RI.......
#=GC seq_cons                        AVLsTDshushLaK.shsp-QL.AhHppVsp.lcKAlVsPtTGuLssSlluAA.CALhu.usssPsss.......pLAphlGsssusLpAAsEpVsToLp-FD..RI.......
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