#=GF ID KH_1
#=GF AC PF00013.33
#=GF DE KH domain
#=GF PI KH-domain; KH;
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Eddy SR;0000-0001-6676-4706
#=GF AU Finn RD;0000-0001-8626-2148
#=GF SE Published_alignment
#=GF GA 21.50 21.50;
#=GF TC 21.50 21.50;
#=GF NC 21.40 21.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF WK KH_domain
#=GF CL CL0007
#=GF RN [1]
#=GF RM 8036511
#=GF RT Conserved structures and diversity of functions of RNA-binding
#=GF RT proteins.
#=GF RA Burd CG, Dreyfuss G;
#=GF RL Science 1994;265:615-621.
#=GF RN [2]
#=GF RM 8612276
#=GF RT Three-dimensional structure and stability of the KH domain:
#=GF RT molecular insights into the fragile X syndrome.
#=GF RA Musco G, Stier G, Joseph C, Castiglione Morelli MA, Nilges M,
#=GF RA Gibson TJ, Pastore A;
#=GF RL Cell 1996;85:237-245.
#=GF DR INTERPRO; IPR004088;
#=GF DR SCOP; 1vig; fa;
#=GF DR MIM; 309550;
#=GF DC syndrome, contains KH motifs.
#=GF DR HOMSTRAD; KH;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC KH motifs bind RNA in vitro. Autoantibodies to Nova, a KH domain
#=GF CC protein, cause paraneoplastic opsoclonus ataxia.
#=GF SQ 155962
#=GS A0A260ZV22_9PELO/147-212 AC A0A260ZV22.1
#=GS A0A444UYU7_ACIRT/59-122 AC A0A444UYU7.1
#=GS A0A0R3UFY6_MESCO/86-149 AC A0A0R3UFY6.1
#=GS A0A1S3R6K0_SALSA/355-422 AC A0A1S3R6K0.1
#=GS A0A4S4ESA8_CAMSI/391-445 AC A0A4S4ESA8.1
#=GS A0A4U1FRC8_MONMO/99-163 AC A0A4U1FRC8.1
#=GS A0A2Y9M518_DELLE/220-280 AC A0A2Y9M518.1
#=GS A0A663F3W7_AQUCH/97-161 AC A0A663F3W7.1
#=GS A0A7K8PSE3_COCCO/32-99 AC A0A7K8PSE3.1
#=GS A0A674CNW3_SALTR/366-426 AC A0A674CNW3.1
#=GS A0A674MPJ6_TAKRU/44-105 AC A0A674MPJ6.1
#=GS A0A8J7THZ6_ATRSP/168-234 AC A0A8J7THZ6.1
#=GS A0A2K5INE7_COLAP/278-345 AC A0A2K5INE7.1
#=GS A0A6P5JD84_PHACI/15-77 AC A0A6P5JD84.1
#=GS A0A4W4FMC7_ELEEL/551-610 AC A0A4W4FMC7.1
#=GS A0A5N6TIC7_9EURO/130-195 AC A0A5N6TIC7.1
#=GS A0A6P6Q2Y4_CARAU/147-212 AC A0A6P6Q2Y4.1
#=GS A0A663MY53_ATHCN/41-102 AC A0A663MY53.1
#=GS F9YQM3_CAPCC/219-271 AC F9YQM3.1
#=GS A0A6P6H8Z5_PUMCO/66-130 AC A0A6P6H8Z5.1
#=GS A0A671R326_9TELE/853-927 AC A0A671R326.1
#=GS A0A8R7PR18_TRIUA/632-696 AC A0A8R7PR18.1
#=GS A0A6G1BGT7_CROCR/200-262 AC A0A6G1BGT7.1
#=GS A0A2U9CCR3_SCOMX/18-80 AC A0A2U9CCR3.1
#=GS A0A7J7HPT2_CAMSI/150-219 AC A0A7J7HPT2.1
#=GS A0A1V6NR47_PENDC/492-575 AC A0A1V6NR47.1
#=GS A0A669EFD4_ORENI/45-107 AC A0A669EFD4.1
#=GS A0A8C3WSE1_9CETA/15-77 AC A0A8C3WSE1.1
#=GS A0A7J8X266_GOSAI/248-320 AC A0A7J8X266.1
#=GS A0A2R6QAY9_ACTCC/121-188 AC A0A2R6QAY9.1
#=GS A0A1X7REE5_ZYMTR/180-245 AC A0A1X7REE5.1
#=GS A0A1C7P705_9HYPH/556-615 AC A0A1C7P705.1
#=GS A0A6J1Z4K2_ACIJB/126-192 AC A0A6J1Z4K2.1
#=GS A0A6J0ZJI6_9ROSI/274-332 AC A0A6J0ZJI6.1
#=GS A0A5Q4C788_9PEZI/554-607 AC A0A5Q4C788.1
#=GS A0A8J5JLT2_HOMAM/46-109 AC A0A8J5JLT2.1
#=GS A0A668U331_OREAU/438-500 AC A0A668U331.1
#=GS A0A1S3USS7_VIGRR/308-366 AC A0A1S3USS7.1
#=GS L8I0D8_9CETA/218-284 AC L8I0D8.1
#=GS A0A8B9M6H3_9AVES/728-791 AC A0A8B9M6H3.1
#=GS A0A6P5DDA6_BOSIN/495-561 AC A0A6P5DDA6.1
#=GS M7NQT3_PNEMU/124-188 AC M7NQT3.1
#=GS A0A5A9PUB6_9TELE/434-496 AC A0A5A9PUB6.1
#=GS A0A556VY72_BAGYA/880-972 AC A0A556VY72.1
#=GS A0A2G5EBU4_AQUCA/178-264 AC A0A2G5EBU4.1
#=GS B4HQ95_DROSE/96-162 AC B4HQ95.1
#=GS A0A4W2GPR4_BOBOX/386-451 AC A0A4W2GPR4.1
#=GS A0A415E4Q5_9FIRM/562-623 AC A0A415E4Q5.1
#=GS A0A074XF48_9PEZI/893-960 AC A0A074XF48.1
#=GS A0A2K6B2Q7_MACNE/283-333 AC A0A2K6B2Q7.1
#=GS A0A671R2R1_9TELE/149-211 AC A0A671R2R1.1
#=GS A0A8C0E4K4_BALMU/356-423 AC A0A8C0E4K4.1
#=GS A0A7L3D1L0_PLUSO/224-286 AC A0A7L3D1L0.1
#=GS A0A6J2I107_9PASS/197-262 AC A0A6J2I107.1
#=GS F6GXK2_VITVI/343-407 AC F6GXK2.1
#=GS W9CJF1_SCLBF/189-254 AC W9CJF1.1
#=GS A0A7K7T781_9TYRA/201-265 AC A0A7K7T781.1
#=GS H2NZA4_PONAB/34-101 AC H2NZA4.2
#=GS A0A6J0XLK3_ODOVR/273-337 AC A0A6J0XLK3.1
#=GS A0A6J2RKV7_COTGO/377-444 AC A0A6J2RKV7.1
#=GS A0A2K5E087_AOTNA/44-94 AC A0A2K5E087.1
#=GS A0A143X5F3_9FIRM/559-619 AC A0A143X5F3.1
#=GS A0A7L1DRK2_OENON/1102-1165 AC A0A7L1DRK2.1
#=GS A0A7L0KYR3_9SYLV/87-153 AC A0A7L0KYR3.1
#=GS A0A2Y9SLU0_PHYMC/93-138 AC A0A2Y9SLU0.1
#=GS A0A6I8UK24_DROPS/135-198 AC A0A6I8UK24.1
#=GS A0A670KPM0_PODMU/110-176 AC A0A670KPM0.1
#=GS A0A7L3AQV3_9AVES/137-199 AC A0A7L3AQV3.1
#=GS RNY_SYNAS/211-273 AC Q2LRA0.1
#=GS A0A8C4EW81_DICLA/376-438 AC A0A8C4EW81.2
#=GS A0A3Q2CFZ8_CYPVA/222-284 AC A0A3Q2CFZ8.1
#=GS A0A7J8A0B4_MYOMY/47-109 AC A0A7J8A0B4.1
#=GS A0A075JNX2_9BACI/554-613 AC A0A075JNX2.1
#=GS A0A8C3A2Z6_CYCLU/217-279 AC A0A8C3A2Z6.1
#=GS W9R3G4_9ROSA/229-297 AC W9R3G4.1
#=GS A0A5M3YLM5_ASPTE/276-351 AC A0A5M3YLM5.1
#=GS A0A445FXV5_GLYSO/141-210 AC A0A445FXV5.1
#=GS W9IVN4_FUSOX/265-338 AC W9IVN4.1
#=GS A0A3Q2GZ80_HORSE/283-352 AC A0A3Q2GZ80.1
#=GS A0A0D3GG99_9ORYZ/504-568 AC A0A0D3GG99.1
#=GS A0A1X2GUE1_9FUNG/123-188 AC A0A1X2GUE1.1
#=GS PNP_MYXXD/555-614 AC Q1DAM1.1
#=GS A0A8B7SRB0_HIPAR/232-296 AC A0A8B7SRB0.1
#=GS A0A6J2VL90_CHACN/28-90 AC A0A6J2VL90.1
#=GS A0A671XY12_SPAAU/80-133 AC A0A671XY12.1
#=GS A0A6P5BAH0_BOSIN/655-718 AC A0A6P5BAH0.1
#=GS A0A8D2JIG6_VARKO/80-144 AC A0A8D2JIG6.1
#=GS A0A3Q2CFZ8_CYPVA/364-424 AC A0A3Q2CFZ8.1
#=GS R5STX3_9FIRM/552-611 AC R5STX3.1
#=GS A0A2J8SX44_PONAB/255-319 AC A0A2J8SX44.1
#=GS A0A3Q1G7E6_9TELE/283-352 AC A0A3Q1G7E6.1
#=GS A0A2X0P0G4_9BASI/114-178 AC A0A2X0P0G4.1
#=GS A0A6I6D9V0_9FIRM/206-261 AC A0A6I6D9V0.1
#=GS A0A2U3ZM55_ODORO/157-222 AC A0A2U3ZM55.1
#=GS D7L188_ARALL/694-754 AC D7L188.1
#=GS A0A850Z445_9PASS/216-283 AC A0A850Z445.1
#=GS A0A2N5S9Z4_9BASI/639-703 AC A0A2N5S9Z4.1
#=GS A0A8B8XD05_BALMU/54-116 AC A0A8B8XD05.1
#=GS A0A818T0Z2_9BILA/71-133 AC A0A818T0Z2.1
#=GS A0A8C4XNI6_FALTI/411-476 AC A0A8C4XNI6.1
#=GS A0A672T6R1_SINGR/147-214 AC A0A672T6R1.1
#=GS A0A6P6NL70_CARAU/231-292 AC A0A6P6NL70.1
#=GS A0A024R4E5_HUMAN/802-865 AC A0A024R4E5.1
#=GS A0A0D9RNG4_CHLSB/195-260 AC A0A0D9RNG4.1
#=GS A0A068UZW8_COFCA/53-106 AC A0A068UZW8.1
#=GS A0A667WKP6_9TELE/341-408 AC A0A667WKP6.1
#=GS A0A3M2SVH5_9EURO/129-194 AC A0A3M2SVH5.1
#=GS A0A0S6XT72_BLOB1/819-900 AC A0A0S6XT72.1
#=GS A0A815M4F0_9BILA/124-189 AC A0A815M4F0.1
#=GS A0A7L1PFH8_ORIOR/407-472 AC A0A7L1PFH8.1
#=GS A0A8D0GMK8_SPHPU/51-96 AC A0A8D0GMK8.1
#=GS A0A7J7RMV7_PIPKU/93-138 AC A0A7J7RMV7.1
#=GS Q0U0F5_PHANO/46-110 AC Q0U0F5.2
#=GS A0A6P5XEL4_DURZI/151-219 AC A0A6P5XEL4.1
#=GS A0A093IL22_FULGA/265-329 AC A0A093IL22.1
#=GS A0A6I6MP04_9CAUL/557-616 AC A0A6I6MP04.1
#=GS A0A7K4Q7U4_MELMO/802-865 AC A0A7K4Q7U4.1
#=GS A0A166YEB6_9GAMM/557-616 AC A0A166YEB6.1
#=GS A0A6P6K7C4_CARAU/332-396 AC A0A6P6K7C4.1
#=GS A0A643C9I3_BALPH/116-180 AC A0A643C9I3.1
#=GS A0A7L1JUW8_RYNNI/365-425 AC A0A7L1JUW8.1
#=GS G3TTW8_LOXAF/153-214 AC G3TTW8.1
#=GS A0A7K7CP95_APHCE/437-499 AC A0A7K7CP95.1
#=GS A0A1S3GGL2_DIPOR/99-163 AC A0A1S3GGL2.1
#=GS A0A672NKR5_SINGR/30-95 AC A0A672NKR5.1
#=GS S3D9T2_OPHP1/43-107 AC S3D9T2.1
#=GS A0A452R8D9_URSAM/23-109 AC A0A452R8D9.1
#=GS A0A8J4Z2N9_9CHEL/116-180 AC A0A8J4Z2N9.1
#=GS G7YAK1_CLOSI/1-67 AC G7YAK1.1
#=GS A0A2U1L254_ARTAN/140-204 AC A0A2U1L254.1
#=GS A0A1L9TYH8_9EURO/217-288 AC A0A1L9TYH8.1
#=GS A0A212C0J2_CEREH/224-270 AC A0A212C0J2.1
#=GS A0A0C1DMX5_9FLAO/212-273 AC A0A0C1DMX5.1
#=GS A0A3N0XEJ1_ANAGA/154-216 AC A0A3N0XEJ1.1
#=GS A0A226N1J8_CALSU/99-163 AC A0A226N1J8.1
#=GS A0A8C5TYJ7_9PASS/35-97 AC A0A8C5TYJ7.1
#=GS A0A7T8QVZ4_CALRO/39-100 AC A0A7T8QVZ4.1
#=GS A0A3P8RX25_AMPPE/122-187 AC A0A3P8RX25.1
#=GS A0A7K4Q7U4_MELMO/437-499 AC A0A7K4Q7U4.1
#=GS A0A834N0S3_VESPE/201-268 AC A0A834N0S3.1
#=GS A0A068VA91_COFCA/177-241 AC A0A068VA91.1
#=GS A0A2K6SHK9_SAIBB/99-163 AC A0A2K6SHK9.1
#=GS A0A671K4M7_9TELE/150-217 AC A0A671K4M7.1
#=GS A0A8C6VH26_NAJNA/88-153 AC A0A8C6VH26.1
#=GS A0A8C4EZD5_DICLA/378-440 AC A0A8C4EZD5.2
#=GS H9FTN7_MACMU/437-499 AC H9FTN7.1
#=GS A0A4Z2IRG3_9TELE/163-229 AC A0A4Z2IRG3.1
#=GS A0A093C3R4_9AVES/98-162 AC A0A093C3R4.1
#=GS A0A2K6ES93_PROCO/573-637 AC A0A2K6ES93.1
#=GS A0A8J5LD06_ZINOF/336-400 AC A0A8J5LD06.1
#=GS A0A8W8N2S7_CRAGI/121-186 AC A0A8W8N2S7.1
#=GS A0A096M8V3_POEFO/62-124 AC A0A096M8V3.1
#=GS G1XAQ2_ARTOA/50-114 AC G1XAQ2.1
#=GS A0A1S3F9C8_DIPOR/286-350 AC A0A1S3F9C8.1
#=GS A0A7J7WHG8_MYOMY/638-701 AC A0A7J7WHG8.1
#=GS A0A6P6KQQ7_CARAU/242-306 AC A0A6P6KQQ7.1
#=GS A0A3Q3MJG8_9TELE/331-395 AC A0A3Q3MJG8.2
#=GS A0A3Q0H7L3_ALLSI/99-163 AC A0A3Q0H7L3.1
#=GS A0A8C3J912_9CHAR/51-117 AC A0A8C3J912.1
#=GS A0A8B6EII7_MYTGA/21-108 AC A0A8B6EII7.1
#=GS A0A7L4ND93_9AVES/828-890 AC A0A7L4ND93.1
#=GS A0A6J3E218_AYTFU/374-441 AC A0A6J3E218.1
#=GS A0A8C8YEX4_PROSS/15-77 AC A0A8C8YEX4.1
#=GS A0A2K5YAT5_MANLE/143-209 AC A0A2K5YAT5.1
#=GS A0A059J8S9_TRIIM/416-480 AC A0A059J8S9.1
#=GS A0A7L0R6D2_SETKR/31-95 AC A0A7L0R6D2.1
#=GS A0A8C8EPC7_ONCTS/123-188 AC A0A8C8EPC7.1
#=GS A0A4Q5Z749_9ACTN/219-278 AC A0A4Q5Z749.1
#=GS A0A852PGR4_9PASS/186-247 AC A0A852PGR4.1
#=GS A0A444ZHM5_ARAHY/315-378 AC A0A444ZHM5.1
#=GS A0A8I3MPP1_CANLF/122-187 AC A0A8I3MPP1.1
#=GS A0A663FE05_AQUCH/220-281 AC A0A663FE05.1
#=GS A0A7J6N1J9_PERCH/743-796 AC A0A7J6N1J9.1
#=GS A0A2U1MDX8_ARTAN/337-406 AC A0A2U1MDX8.1
#=GS A0A0D9UYK7_9ORYZ/458-527 AC A0A0D9UYK7.1
#=GS A0A7K5R1A1_9PASE/513-579 AC A0A7K5R1A1.1
#=GS L5LHR5_MYODS/237-297 AC L5LHR5.1
#=GS A0A2Y9KDE2_ENHLU/270-334 AC A0A2Y9KDE2.1
#=GS A0A445JR52_GLYSO/142-210 AC A0A445JR52.1
#=GS A0A8C2ZQT6_CYCLU/921-984 AC A0A8C2ZQT6.1
#=GS A0A6I9WZX2_9HYME/157-209 AC A0A6I9WZX2.1
#=GS A0A1S3FCN8_DIPOR/377-444 AC A0A1S3FCN8.1
#=GS A0A656KPL9_BLUGR/199-274 AC A0A656KPL9.1
#=GS A0A8J6GGK4_MICOH/463-525 AC A0A8J6GGK4.1
#=GS A0A4W4FPB7_ELEEL/168-232 AC A0A4W4FPB7.1
#=GS A0A6J2TGX4_DROLE/291-363 AC A0A6J2TGX4.1
#=GS A0A8B9WZN2_BOSMU/78-141 AC A0A8B9WZN2.1
#=GS A0A8C5B661_GADMO/93-157 AC A0A8C5B661.1
#=GS A0A667WKN1_9TELE/243-307 AC A0A667WKN1.1
#=GS A0A4W3K0K1_CALMI/349-414 AC A0A4W3K0K1.1
#=GS A0A7L3XGZ6_9AVES/257-308 AC A0A7L3XGZ6.1
#=GS A0A2Y9Q5B7_DELLE/376-440 AC A0A2Y9Q5B7.1
#=GS A0A0E3YX45_9BACT/191-253 AC A0A0E3YX45.1
#=GS A0A8C9YCK6_SANLU/43-110 AC A0A8C9YCK6.1
#=GS A0A0L0CLR6_LUCCU/25-90 AC A0A0L0CLR6.1
#=GS A0A671M7A1_9TELE/292-357 AC A0A671M7A1.1
#=GS I0ZA07_COCSC/248-312 AC I0ZA07.1
#=GS A0A3Q1J7V7_ANATE/653-716 AC A0A3Q1J7V7.1
#=GS A0A7L1Q386_ORIOR/296-358 AC A0A7L1Q386.1
#=GS I1LCN2_SOYBN/253-320 AC I1LCN2.1
#=GS A0A6P8QAC0_GEOSA/329-393 AC A0A6P8QAC0.1
#=GS A0A3S2NHV0_CHISP/222-283 AC A0A3S2NHV0.1
#=GS K7DG73_PANTR/386-451 AC K7DG73.1
#=GS A0A7E5VIA9_TRINI/210-276 AC A0A7E5VIA9.1
#=GS A0A6L7GGG4_9SPHN/553-612 AC A0A6L7GGG4.1
#=GS A0A8C5U7U9_9PASS/419-484 AC A0A8C5U7U9.1
#=GS A0A2I0M426_COLLI/242-306 AC A0A2I0M426.1
#=GS A0A6J2YIG7_SITOR/133-195 AC A0A6J2YIG7.1
#=GS A0A7K6HR61_9PASS/24-86 AC A0A7K6HR61.1
#=GS A0A6A5LGS5_LUPAL/211-275 AC A0A6A5LGS5.1
#=GS A0A6J0XMJ5_ODOVR/285-349 AC A0A6J0XMJ5.1
#=GS A0A0C9MK08_9FUNG/147-211 AC A0A0C9MK08.1
#=GS R9AEF1_WALI9/1260-1317 AC R9AEF1.1
#=GS PNP_EDWI9/555-614 AC C5BFC1.1
#=GS A0A7J8JZ26_MOLMO/51-109 AC A0A7J8JZ26.1
#=GS K7FTK6_PELSI/151-213 AC K7FTK6.1
#=GS A0A673KL30_9TELE/15-77 AC A0A673KL30.1
#=GS A0A669BV48_ORENI/283-354 AC A0A669BV48.1
#=GS A0A672J8T5_SALFA/15-76 AC A0A672J8T5.1
#=GS A0A164Q2E4_9CRUS/928-990 AC A0A164Q2E4.1
#=GS A0A3Q1I9B3_ANATE/1129-1192 AC A0A3Q1I9B3.1
#=GS A0A1M7SRT8_9DELT/210-271 AC A0A1M7SRT8.1
#=GS A0A2K6BXR2_MACNE/15-77 AC A0A2K6BXR2.1
#=GS A0A3P8YX14_ESOLU/729-792 AC A0A3P8YX14.2
#=GS A0A7L3CBG7_PELUR/58-123 AC A0A7L3CBG7.1
#=GS A0A5E4BH10_MARMO/324-388 AC A0A5E4BH10.1
#=GS A0A4W6D2T6_LATCA/576-639 AC A0A4W6D2T6.1
#=GS A0A7K9P5Q5_9CORV/30-94 AC A0A7K9P5Q5.1
#=GS B4QCF3_DROSI/452-514 AC B4QCF3.1
#=GS A0A7L1X7R5_9AVES/249-299 AC A0A7L1X7R5.1
#=GS A0A7L3FNR5_9GRUI/16-78 AC A0A7L3FNR5.1
#=GS A0A8C8DG42_ONCTS/330-397 AC A0A8C8DG42.1
#=GS A0A0F7VEI0_PENBI/540-593 AC A0A0F7VEI0.1
#=GS A0A2P4T7I2_BAMTH/247-297 AC A0A2P4T7I2.1
#=GS A0A7L0LAJ3_9SYLV/355-419 AC A0A7L0LAJ3.1
#=GS A0A0P7HY55_9MOLU/216-276 AC A0A0P7HY55.1
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