GenomeNet

Database: Pfam
Entry: LLCFC1
LinkDB: LLCFC1
Original site: LLCFC1 
#=GF ID   LLCFC1
#=GF AC   PF15838.8
#=GF DE   LLLL and CFNLAS motif-containing protein 1
#=GF PI   DUF4717;
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:Q96L11
#=GF GA   27.00 27.00;
#=GF TC   28.70 28.40;
#=GF NC   26.00 18.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   32393636
#=GF RT   Sperm proteins SOF1, TMEM95, and SPACA6 are required for
#=GF RT   sperm-oocyte fusion in mice.
#=GF RA   Noda T, Lu Y, Fujihara Y, Oura S, Koyano T, Kobayashi S, Matzuk
#=GF RA   MM, Ikawa M;
#=GF RL   Proc Natl Acad Sci U S A. 2020;117:11493-11502.
#=GF DR   INTERPRO; IPR031684;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   LLCFC1 (also known as SOF1) and its homologues can be found in
#=GF CC   eukaryotes. They have two conserved sequence motifs: LLLL and
#=GF CC   CFNLAS. LLCFC1 is a sperm protein required for sperm-oocyte
#=GF CC   fusion in mice [1].
#=GF SQ   102
#=GS A0A1S2ZP66_ERIEU/29-105   AC A0A1S2ZP66.1
#=GS H0X9B5_OTOGA/32-103       AC H0X9B5.1
#=GS A0A2U3V5B0_TURTR/34-105   AC A0A2U3V5B0.1
#=GS A0A7N4PEP6_SARHA/33-110   AC A0A7N4PEP6.1
#=GS A0A6J2MLK3_9CHIR/38-109   AC A0A6J2MLK3.2
#=GS L9L136_TUPCH/33-104       AC L9L136.1
#=GS A0A2Y9D021_HUMAN/62-133   AC A0A2Y9D021.1
#=GS A0A643BLW6_BALPH/37-108   AC A0A643BLW6.1
#=GS A0A670JYY2_PODMU/32-96    AC A0A670JYY2.1
#=GS H2RIB5_PANTR/56-127       AC H2RIB5.1
#=GS A0A3Q7R7G5_VULVU/77-148   AC A0A3Q7R7G5.1
#=GS A0A2K5JN42_COLAP/31-102   AC A0A2K5JN42.1
#=GS A0A6J0A549_ACIJB/39-110   AC A0A6J0A549.1
#=GS A0A4U1FK29_MONMO/34-105   AC A0A4U1FK29.1
#=GS W5Q6S1_SHEEP/78-149       AC W5Q6S1.1
#=GS A0A3P4NLX4_GULGU/77-148   AC A0A3P4NLX4.1
#=GS A0A6P3F2S7_OCTDE/35-105   AC A0A6P3F2S7.1
#=GS A0A6P3R744_PTEVA/109-179  AC A0A6P3R744.1
#=GS A0A151NL33_ALLMI/15-80    AC A0A151NL33.1
#=GS G1QE25_MYOLU/34-107       AC G1QE25.1
#=GS A0A2K6MKY9_RHIBE/36-107   AC A0A2K6MKY9.1
#=GS A0A3M0K896_HIRRU/36-103   AC A0A3M0K896.1
#=GS A0A2K5UZC7_MACFA/21-92    AC A0A2K5UZC7.2
#=GS A0A7N5K786_AILME/66-137   AC A0A7N5K786.1
#=GS A0A6P3EQP2_OCTDE/37-108   AC A0A6P3EQP2.1
#=GS D4A4Y5_RAT/35-105         AC D4A4Y5.1
#=GS H2PNU6_PONAB/31-102       AC H2PNU6.1
#=GS A0A2I3MJN1_PAPAN/55-126   AC A0A2I3MJN1.1
#=GS A0A6J0ARI0_VICPA/82-153   AC A0A6J0ARI0.1
#=GS A0A2Y9HA17_NEOSC/77-148   AC A0A2Y9HA17.1
#=GS A0A7N9CFX7_MACFA/31-102   AC A0A7N9CFX7.1
#=GS A0A452G1P2_CAPHI/34-105   AC A0A452G1P2.1
#=GS J9P6T1_CANLF/59-130       AC J9P6T1.2
#=GS A0A672UK12_STRHB/5-78     AC A0A672UK12.1
#=GS A0A452GQR9_9SAUR/10-81    AC A0A452GQR9.1
#=GS A0A2I2YEI8_GORGO/56-127   AC A0A2I2YEI8.1
#=GS A0A1S3FMM5_DIPOR/34-105   AC A0A1S3FMM5.1
#=GS A0A212CK85_CEREH/76-147   AC A0A212CK85.1
#=GS A0A0Q3XA66_AMAAE/44-115   AC A0A0Q3XA66.1
#=GS A0A673SRE1_SURSU/39-110   AC A0A673SRE1.1
#=GS F7IH73_CALJA/56-124       AC F7IH73.3
#=GS A0A6P5L5M8_PHACI/35-113   AC A0A6P5L5M8.1
#=GS A0A6P3IFW3_BISBI/131-202  AC A0A6P3IFW3.1
#=GS A0A6P6IAE1_PUMCO/122-193  AC A0A6P6IAE1.1
#=GS A0A2K5C3N1_AOTNA/56-127   AC A0A2K5C3N1.1
#=GS A0A1A6HBB9_NEOLE/35-105   AC A0A1A6HBB9.1
#=GS A0A384CMG7_URSMA/77-148   AC A0A384CMG7.1
#=GS A0A2K5MYH1_CERAT/55-126   AC A0A2K5MYH1.1
#=GS LCFC1_MOUSE/37-107        AC Q9D9P8.1
#=GS A0A7N9CV91_MACFA/68-139   AC A0A7N9CV91.1
#=GS A0A5N3XSW7_MUNRE/34-105   AC A0A5N3XSW7.1
#=GS A0A2K5PH77_CEBIM/56-127   AC A0A2K5PH77.1
#=GS G5C2L1_HETGA/49-121       AC G5C2L1.1
#=GS A0A340Y4W3_LIPVE/34-105   AC A0A340Y4W3.1
#=GS A0A2K6C7N1_MACNE/31-102   AC A0A2K6C7N1.1
#=GS A0A2Y9K9H7_ENHLU/39-110   AC A0A2Y9K9H7.1
#=GS A0A402FAL5_9SAUR/23-92    AC A0A402FAL5.1
#=GS A0A6I9M7A8_PERMB/40-110   AC A0A6I9M7A8.1
#=GS A0A2Y9FFL8_PHYMC/34-105   AC A0A2Y9FFL8.1
#=GS G1QRE8_NOMLE/56-127       AC G1QRE8.1
#=GS A0A341CGF3_NEOAA/34-105   AC A0A341CGF3.1
#=GS A0A0D9R4U9_CHLSB/31-102   AC A0A0D9R4U9.1
#=GS A0A2F0B6W5_ESCRO/34-105   AC A0A2F0B6W5.1
#=GS G3HL24_CRIGR/13-84        AC G3HL24.1
#=GS A0A5N4DYZ6_CAMDR/38-109   AC A0A5N4DYZ6.1
#=GS A0A493TWL9_ANAPP/31-95    AC A0A493TWL9.1
#=GS M3WLM6_FELCA/39-110       AC M3WLM6.2
#=GS A0A1U7U111_CARSF/75-146   AC A0A1U7U111.2
#=GS A0A2Y9DXN3_TRIMA/35-105   AC A0A2Y9DXN3.1
#=GS A0A2I3TT59_PANTR/31-102   AC A0A2I3TT59.1
#=GS A0A2R8Z7V5_PANPA/56-127   AC A0A2R8Z7V5.1
#=GS A0A2K6T0E5_SAIBB/56-126   AC A0A2K6T0E5.1
#=GS S9WX95_CAMFR/38-109       AC S9WX95.1
#=GS G3QY88_GORGO/11-82        AC G3QY88.2
#=GS I3MBG9_ICTTR/34-105       AC I3MBG9.2
#=GS L8I921_9CETA/34-105       AC L8I921.1
#=GS A0A2Y9NIR3_DELLE/34-105   AC A0A2Y9NIR3.1
#=GS A0A485PUB3_LYNPA/34-105   AC A0A485PUB3.1
#=GS G1STB5_RABIT/76-147       AC G1STB5.2
#=GS A0A091CWD4_FUKDA/99-162   AC A0A091CWD4.1
#=GS A0A0J9YWY1_HUMAN/61-132   AC A0A0J9YWY1.1
#=GS L5LLW2_MYODS/34-107       AC L5LLW2.1
#=GS A0A2K6R467_RHIRO/31-102   AC A0A2K6R467.1
#=GS S7PCM8_MYOBR/34-107       AC S7PCM8.1
#=GS A0A2K6EZA0_PROCO/45-116   AC A0A2K6EZA0.1
#=GS A0A6I9MN45_PERMB/35-105   AC A0A6I9MN45.1
#=GS A0A384ACC6_BALAS/34-105   AC A0A384ACC6.1
#=GS A0A2U3WYB4_ODORO/77-148   AC A0A2U3WYB4.1
#=GS A0A3Q7MTU9_CALUR/134-205  AC A0A3Q7MTU9.1
#=GS A0A1D5QCN8_MACMU/31-102   AC A0A1D5QCN8.2
#=GS A0A287A9B6_PIG/39-109     AC A0A287A9B6.1
#=GS A0A3Q0D7U4_MESAU/85-156   AC A0A3Q0D7U4.1
#=GS A0A2U3YJ44_LEPWE/39-110   AC A0A2U3YJ44.2
#=GS H0WDR1_CAVPO/39-110       AC H0WDR1.2
#=GS A0A674ILE3_TERCA/53-112   AC A0A674ILE3.1
#=GS LCFC1_HUMAN/31-102        AC Q96L11.1
#=GS A0A6J3F664_SAPAP/74-145   AC A0A6J3F664.1
#=GS A0A6I9JEY0_CHRAS/35-105   AC A0A6I9JEY0.1
#=GS A0A151NL17_ALLMI/23-94    AC A0A151NL17.1
#=GS A0A6J0XCN6_ODOVR/83-154   AC A0A6J0XCN6.1
#=GS G5ALH7_HETGA/84-156       AC G5ALH7.1
#=GS A0A3Q7WCV7_URSAR/77-148   AC A0A3Q7WCV7.1
A0A1S2ZP66_ERIEU/29-105              .................qnedqd-SEGEAQKDNLPS.IDQDQEQLEEHFLASSVGEMWQVVDMAQ.QEDQEMS......QAREIHNH.LFDLAFCFNLASILVF......................
H0X9B5_OTOGA/32-103                  ......................s-PGSEEREEETPS.PDQNQEQFEEHFMISSVGEMWQVMDMAQ.QEEDKTS......ETAALHDH.LFYLAFCFNLASIMIF......................
A0A2U3V5B0_TURTR/34-105              .....................gl--DERSQKEKTPS.TDQDGEQFAEHFVASSVGELWQAVDMTQ.QEDEQMS......EAVASRGH.LFHLAFCLNLAGTVVF......................
A0A7N4PEP6_SARHA/33-110              ...................dpng--NGRSQKEEGAS.--PGEEQLEEQFVASSIGEILQLLTMGP.SEEEEAEveveaeENTAVRDH.LFDLAFCFNLASILL-s.....................
A0A6J2MLK3_9CHIR/38-109              ......................g-PNERSQEEKIPS.ADQNQEQYEEYFVASSVGESWQKVDMAQ.QEDDKTV......EDAAVCEH.LFDLALCLNLASAMVF......................
L9L136_TUPCH/33-104                  .......................GPDERSQNEKTPS.TDQDQEQFEEHFMASSVGEMWQVMDMVQ.QEEDTTS......KAATVHDH.LLDLAFCLNLASIVVF......................
A0A2Y9D021_HUMAN/62-133              ......................g-PKDGSQTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDQSS......KTAAVHKH.SFHLSFCFSLASVMVF......................
A0A643BLW6_BALPH/37-108              .....................gl--DESSQKEKTPS.TDQDREQFEEHFVASSVGELWQAVDMTQ.QEDDQTS......EAVAICDH.LFDLAFCFNLASIVVF......................
A0A670JYY2_PODMU/32-96               ...........gshensmqicgg-------------.------KMEETFVASSTGEGMEVIDMAE.SEDSQLL......GNAAVKDM.LLDLAVSLNTASVMLF......................
H2RIB5_PANTR/56-127                  ......................g-PKDGSQTEKMPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDQSS......KTAAVHKH.SFHLSFCFSLASVMVF......................
A0A3Q7R7G5_VULVU/77-148              ......................d-SNEKSQTEEIPS.TDQDEDHLEEHFVASSVGEMWQVVDMAQ.QEDDKTS......DTAALRDH.LFDLAFCFNLASIMVF......................
A0A2K5JN42_COLAP/31-102              ......................g-PKDGSQTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDKSS......KTSAIHKH.SFHLGFCISLASVMVF......................
A0A6J0A549_ACIJB/39-110              .......................DPNERSQNEKTPS.TDQDQENFEEHFVASSVGEMWQVVDMAQ.QEDDGTS......DTAALRDH.LFNLAFCFNLASIMVF......................
A0A4U1FK29_MONMO/34-105              .....................dl--DERSQKEKIPS.TDQDGEQFAEHFVASSVGELWQAVDMTQ.QEDEQTS......EAVASRGR.LLDLAFCFNLAGTVVF......................
W5Q6S1_SHEEP/78-149                  .....................gl--DERSQKEKTPS.TDQDREQFEEHFMASSVGETWQVVDMAQ.QEADETS......EVAAIRDH.LFDLAFCFNLASIMVF......................
A0A3P4NLX4_GULGU/77-148              .......................DPNEKSQNEEIPS.TDQDQEYFEEHFVASSVGEMWQTVDMTQ.QEDDKTS......DTAALRDH.LLDLAFCFNLASIMVF......................
A0A6P3F2S7_OCTDE/35-105              .....................gp--VQRSLVEKTPP.AEQGQEQYEEHFMASSLGERWQQ-DMTR.SQEDFTS......EKAAVQGH.LFELTLCFNLASFMVF......................
A0A6P3R744_PTEVA/109-179             ......................g-PDERSWKAKTLS.ADQEQEQFEEHFAVSSVGEMWEVVDMAQ.QE-DKTS......ENAALRDH.LADLAFCFNLASIVVF......................
A0A151NL33_ALLMI/15-80               sdsegqamvqgdkdklleegspp-------------.----------------AGEGMEVINMMQ.SDESQRL......RNSAVKDL.LLDLAISLNTGSIVLF......................
G1QE25_MYOLU/34-107                  ......................g-PNERSQKEQMPS.KDQNQEQFEEYFVASSVGEMWQEVNMAQ.QEDDKTSe....mENTAVRDH.LFDLALCFNVASVLVF......................
A0A2K6MKY9_RHIBE/36-107              ......................g-PKVGSQTEKMPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDKSS......KTSAIHKH.SFHLGLSISLASVMVF......................
A0A3M0K896_HIRRU/36-103              ....................irn---AENEQEQESS.PRAGWEEMEESFVASSTGEGMEVIDMVE.PEDSEAL......SNSALKDL.LLDPALLL--------kivf..................
A0A2K5UZC7_MACFA/21-92               ......................g-KKDGSRTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDKSS......KTSAIHKP.SSTLGFCFSLASVMIF......................
A0A7N5K786_AILME/66-137              .......................DPNEGSQNKEIPS.TEQDQEQFEEHFVASSVGEMWQVVDMAQ.QEDDKTS......DTAALRDH.LSDLAFCSSLASILVF......................
A0A6P3EQP2_OCTDE/37-108              .....................gp--VQRSLVEKTPP.AEQGQEQYEEHFMASSVGEKWQEVDMVR.QEEDFTS......ETAAVQDH.LFSLALCFNLASIMVF......................
D4A4Y5_RAT/35-105                    ......................l-DGDKSPKEKMSS.KDQGEQQYEEHFVASSVGELWQVVDMAQ.QE-DTNS......KASAIRDH.LFDLAFCFNLASIVFF......................
H2PNU6_PONAB/31-102                  ......................g-PKDGSQIQKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDQSS......KTAAVHKH.SFHLSFCFSLASIMVF......................
A0A2I3MJN1_PAPAN/55-126              ......................g-PKDGSQTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDKSS......KTSAIHKP.SFHLGFCFSLASVMIF......................
A0A6J0ARI0_VICPA/82-153              ......................a-PSERRQEEETPA.ADQDREQFEEHFVASSVGEMRQVVDMAQ.QEDDRTS......KTAALRDH.LFDFTFCFNLASIMVF......................
A0A2Y9HA17_NEOSC/77-148              .......................DPNERSQNEKIPS.TDQDQEHFEEHFVASSVGEMWQIVDMAQ.QEDDKTS......NTAALRDH.LLDLAFCFNLASIMVF......................
A0A7N9CFX7_MACFA/31-102              ......................g-PKDGSQTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDKSS......KTSAIHKP.SFHLGFCFSLASVMIF......................
A0A452G1P2_CAPHI/34-105              .....................gl--DERSQKEKTPS.TDQDREQFEEHFMASSVGETWQVVDMAQ.QEDDKTS......EVAAIRDH.LFDLAFCFNLASIMVF......................
J9P6T1_CANLF/59-130                  ......................d-SNEKSQTEEIPS.TDQDEDHLEEHFVASSVGEMWQVVDMAQ.QEDDKTS......DTAALRDH.LFDLVFCFNLASIMVF......................
A0A672UK12_STRHB/5-78                .............kqvkgekfrp-------------.-GKDWEQMEETFVASSTGEGTEVIDMVQ.HKDSQRL......RNSAVKDL.----------------heiiamvidnnlniylcfmiss
A0A452GQR9_9SAUR/10-81               ............plkrqrgelms-----------PS.WVTGWEQMEETFVASSTGEGMELIDMVQ.NEDAQRL......RNSVVKDL.LLDLAISLNTGSIMLF......................
A0A2I2YEI8_GORGO/56-127              ......................g-PKDGSQTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDQSS......KTAAVHKH.SFHLSFCFSLASVMVF......................
A0A1S3FMM5_DIPOR/34-105              .......................DPDDRSQKENMPS.AEQDQEQFEEHFVASSVGELWQMIDMAQ.QEEDTIS......KTAAVRDH.LFNLAFCFNLASIMVF......................
A0A212CK85_CEREH/76-147              .....................gl--DERSQKEKTPS.TDQDREQFEERFMASSVGEMWHVVDMAQ.QEDDKTS......EVAAIRDH.LFDLAFCFNLASIMVF......................
A0A0Q3XA66_AMAAE/44-115              ....................iat---NEQQEQNSPS.AGEDWEHMEETFVASSTGEGTEVIDMVQ.HEDSEGL......RNSAVKDL.VLDLALALSAGSVVLF......................
A0A673SRE1_SURSU/39-110              .......................DPNERSQNEKIPS.TDQDQEHFEEHFVASSVGEMWQAVNMAQ.QEDDETS......DTAALRDH.LFDLAFCFNLASIMVF......................
F7IH73_CALJA/56-124                  ......................v-PKARSQTEKTTF.AEQNQEQFEEYFVASSVGEMWQAVDMAQ.QEDDETS......KTAAVHHH.SFHLNFCFSLA-----pa....................
A0A6P5L5M8_PHACI/35-113              .....................ng--NGRSQKEKKASlTGEGEEELEEHFVASSVGEMLQLLTMEHsQEEEAEVea.eveEGTAVRDR.LFDLAFCFNIASILAF......................
A0A6P3IFW3_BISBI/131-202             .....................gl--DERSQKEKTPS.TDQDREQFEEHFMASSVGEMWQVVDMAQ.QEDDKTS......EVAAIRDH.LFDLAFCFNLASIMVF......................
A0A6P6IAE1_PUMCO/122-193             .......................DPNERSQNEKTPS.TDQDQENFEEHFVASSVGEMWQVVDMAQ.QEDDGTS......DTAALRDH.LFNLAFCFNLASIMVF......................
A0A2K5C3N1_AOTNA/56-127              ......................v-PKDRSQTEKTTF.AEQNQEQFEEHFVASSVGEMWQAVDMAQ.QEDDETS......KTAAVHHH.SFHLSFCFSLASVMVF......................
A0A1A6HBB9_NEOLE/35-105              ......................l-DNEGSQREKMVS.ADQGQEQFEEHFVASSVGELWQVIDMAQ.QE-DTXA......QATTIRDH.LFDLAFCFNLASIIIF......................
A0A384CMG7_URSMA/77-148              .......................DPNEGSQNEEIPS.TDQDQEQFEEHFVASSVGEMWQVVDMAQ.QEDDKTS......DTAALRDH.LLDLAFCFNLASIMVF......................
A0A2K5MYH1_CERAT/55-126              ......................g-PKDGSQTEKTPF.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDKSS......KTSAIHKP.SFHLGFCFSLASVMIF......................
LCFC1_MOUSE/37-107                   ......................l-DGDKSQKDKVSS.EDQGEEEYEEHFEASSEGEQWQEIDMVQ.QE-DTIS......QAITLQDH.LLDLAFCFNLASIMFF......................
A0A7N9CV91_MACFA/68-139              ......................g-PKDGSQTEKMPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDKSS......KTSAIHKP.SSTLGFCFSLASVMIF......................
A0A5N3XSW7_MUNRE/34-105              .......................DPDERSQKEKTPS.TDQDREQFEERFMVSSVGEMWHVVDMAQ.QEDDKTS......EVAAIRDH.LFDLAFCFNLASIMVF......................
A0A2K5PH77_CEBIM/56-127              ......................g-PKDRSQTEKTTF.AEQNQEEFEEHFVASSVGEMWQAVDMAQ.QEDDETS......ETAAVHHH.PFHLGFCFSLASLTVF......................
G5C2L1_HETGA/49-121                  ......................g-PEEGALEEKTPP.AEQGQEQYEEHFMASSEGEKWQVMDMAR.QEEDFTS......DTAAAQDHrLFDLALCFNLASIMVF......................
A0A340Y4W3_LIPVE/34-105              .....................gl--DERSQKEKTPS.TDQDREQFAERFVASSVGELWQAVDMTQ.QEDEQTS......EAVASRGR.LFDLASCFNLASIVVF......................
A0A2K6C7N1_MACNE/31-102              ......................g-PKDGSQTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDKSS......KTSAIHKP.SFHLGFCFSLASVMIF......................
A0A2Y9K9H7_ENHLU/39-110              .......................DPNEKSQNEEIPS.TDQDQEYFEEHFVASSVGEMWQTVDMTQ.QEDDKTS......DTTALRDH.LLDLAFCFNLASIMVF......................
A0A402FAL5_9SAUR/23-92               ................shaflgq---------TTSK.KDKEGGKMEETFVASSTGEGMEVINMAQ.DEESQRL......GNAAVKDI.LLDLAISLNTASVMLF......................
A0A6I9M7A8_PERMB/40-110              ......................l-DEDRSQREKTVS.ADLGQEQFEEHFVASSVGELWQVMDMAQ.EE-DMIA......QATTIRDH.LFDVAFCFNLASIMIF......................
A0A2Y9FFL8_PHYMC/34-105              .....................gl--DERSHKEKTPS.TDQDQEQFEEYFVASSVGELWQAVDMTQ.QEDDQTS......EAVASRGR.LFDLAFCFNLASIVVF......................
G1QRE8_NOMLE/56-127                  ......................g-PKDGSQTEKMPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDQSP......KTAAVHKY.SFHLSFCFSLASVMVF......................
A0A341CGF3_NEOAA/34-105              .....................dl--DERSQKEKTPS.SDQDGEQFAEHFVASSVGELWQAVDMTQ.QEDEQTS......EAVASRGC.LLNLAFCFNLAGTVVF......................
A0A0D9R4U9_CHLSB/31-102              ......................g-PKDGSQTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDKLS......KTSAVHKH.SFHLGFCFGLASVMVF......................
A0A2F0B6W5_ESCRO/34-105              .....................gl--DESSQKEKTPS.TDRDREQFEEHFVASSVGELWQAVDMTQ.QEDDQTS......EAAAICDH.LFDLAFCFNLAGIVVF......................
G3HL24_CRIGR/13-84                   ......................l-DDGRSQKEKVFS.VDEGKEQFEEHFMASSVGELWQVIDMAQ.QEEDTFA......QAATFRDH.LFDLAFCFNLASIMVF......................
A0A5N4DYZ6_CAMDR/38-109              ......................a-PSERRQEEETLA.ADQDREQFEEHFVASSVGEMRQVVDMAQ.QEDDRTS......KTAALRDH.LFDFTFCFNLASIMVF......................
A0A493TWL9_ANAPP/31-95               .............nkgeklccpy-----------PS.LAAGWEQMEETFVASSTGEGMELINMVQ.QEDYQRL......RNSAVKDL.LLN-------------qceiivv...............
M3WLM6_FELCA/39-110                  .......................DPNERSQNEKTPS.TDQDQENFEEHFVASSVGEMWQVVDMAQ.QEDDGTS......DRAALRDH.LFNLAFCFNLASIMVF......................
A0A1U7U111_CARSF/75-146              ......................g-PEERSQREKTPS.PDQNQEQFEEHFVASSVGEMWQVMDMAQ.QEEDKTS......ETAALREH.LFYLAFCFNLASIMVF......................
A0A2Y9DXN3_TRIMA/35-105              ......................d-PAENSQKDSMPS.TDQDEEQFEERFVASSVGEMWQQLDMTQ.QE-DEVA......EAAAVRDH.LFDLAFCLNLASIMVF......................
A0A2I3TT59_PANTR/31-102              ......................g-PKDGSQTEKMPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDQSS......KTAAVHKH.SFHLSFCFSLASVMVF......................
A0A2R8Z7V5_PANPA/56-127              ......................g-PKDGSQTEKMPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDQSS......KTAAVHKH.SFHLSFCFSLASVMVF......................
A0A2K6T0E5_SAIBB/56-126              ......................g-PKDRSQTEKTTF.AEQNQEEFEEHFVASSVGEMWQAVDMAQ.QE-DETS......KTAAVHHH.SFHLGFCFSLASVMVF......................
S9WX95_CAMFR/38-109                  ......................a-PSERRQEEETLA.ADQDREQFEEHFVASSVGEMCQVVDMAQ.QEDDRTS......KTAALRDH.LFDFTFCFNLASIMVF......................
G3QY88_GORGO/11-82                   ......................g-PKDGSQTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDQSS......KTAAVHKH.SFHLSFCFSLASVMVF......................
I3MBG9_ICTTR/34-105                  ......................d-MDEGKQKEKMAS.ADQNQEQFEEHFLASSVGELWQVMDMAQ.QEENTTS......KAAAVRDH.LFDLAFCFNMASIMFF......................
L8I921_9CETA/34-105                  .....................gl--DERSQKEKTPS.TDQDREQFEEHFMASSVGEMWQVVDMAQ.QEDDKTS......EVAAIRDH.LFDLAFCFNLASIMVF......................
A0A2Y9NIR3_DELLE/34-105              .....................dl--DERSQKEKTPS.TDQDGEQFAEHFVASSVGELWQAVDMTQ.QEDEQTS......EAVASRGR.LLDLAFCFNLAGTVVF......................
A0A485PUB3_LYNPA/34-105              .......................DPNERSQNEKTPS.TDQDQENFEEHFVASSVGEMWQVVDMAQ.QEDDGTS......DTAALRDH.LFNLAFCFNLASIMVF......................
G1STB5_RABIT/76-147                  .......................DPDGKNQEEQISS.EDQNQEMYEERFVASSVGELWQVVDMAQ.QEEDMTS......ESAVIRDH.LFDLAFCFNLASIMVF......................
A0A091CWD4_FUKDA/99-162              ..................gggsv-------------.REQGQEQYEEHFMASSVGEKWQVVDMVQ.QEEDFIS......EAAAVQDR.RFYFALCFNLASIMAF......................
A0A0J9YWY1_HUMAN/61-132              ......................g-PKDGSQTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDQSS......KTAAVHKH.SFHLSFCFSLASVMVF......................
L5LLW2_MYODS/34-107                  ......................g-PSERSQKAQMAS.TDQNQEQFEEYFVASSVGEMWQEVNMAQ.QEDDKTSe....mENTAVRDH.LFDLALCFNVASVLVF......................
A0A2K6R467_RHIRO/31-102              ......................g-PKVGSQTEKMPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDKSS......KTSAIHKH.SFHLGLSISLASVMVF......................
S7PCM8_MYOBR/34-107                  ......................g-PNERSQKEQMPS.KDQNQEQFEEYFVASSVGEMWQEVNMAQ.QEDEKTSe....mENTAVRDH.LFDLALCFNVASVLVF......................
A0A2K6EZA0_PROCO/45-116              .....................gl--EETSQKEETPS.PDQNQEQFEEHFVASSVGEMWQVMDMAQ.QEEDRTS......ETAAVLDH.VFHLAFCFSLASVVIF......................
A0A6I9MN45_PERMB/35-105              ......................l-DEDRSQREKTVS.ADLGQEQFEEHFVASSVGELWQVMDMAQ.EE-DMIA......QATTIRDH.LFDVAFCFNLASIMIF......................
A0A384ACC6_BALAS/34-105              .....................gl--DESSQKEKTPS.TDQDREQFEEHFVASSVGELWQAVDMTQ.KEDDQTS......EAVAICDH.LFDLAFCFNLASIVVF......................
A0A2U3WYB4_ODORO/77-148              .......................DPNERSQNEKIPS.TDQDQEHFEEHFVASSVGEMWQIVDMAQ.QEDDKTS......NTAALRDH.LLDLAFCFNLASIMVF......................
A0A3Q7MTU9_CALUR/134-205             .......................DPNERSQNEKIPS.TDQDQEHFEEHFVASSVGEMWQTVDMAQ.QEDDKTS......NTAALRDH.LLDLAFCFNMASIMVF......................
A0A1D5QCN8_MACMU/31-102              ......................g-PKDGSQTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDKSS......KTSAIHKP.SFHLGFCFSLASVMIF......................
A0A287A9B6_PIG/39-109                ......................g-PDERGQKEKTPS.TDPEQEQFEEHFVASSVGEMWQMVDMAQ.QE-DKRS......ETAAIRDH.LFDLAFCLNLASIMVF......................
A0A3Q0D7U4_MESAU/85-156              ......................l-DDGGSQKEKVLS.VDQGQEQFEEHFMASSVGELLQVIDMAQ.QEEDAIA......QAATLWDH.LFDLAFCFNLASMVFF......................
A0A2U3YJ44_LEPWE/39-110              .......................DPNERSQNEKIPS.TDQDQEHFEEHFVASSVGEMWQIVDMAQ.QEDDKTS......NTAALRDH.LLDLAFCFNLASIMVF......................
H0WDR1_CAVPO/39-110                  ......................g-PGEKSLEGKMPP.AEQGQELYEEHFMASSVGEQWQEVDMAQ.QEDDITS......ETAGIQDY.LFDLAFCFNLASIMLF......................
A0A674ILE3_TERCA/53-112              ................ergeqav-------KLMSPS.RVAGWEQMEETFVASSTGEGMEVIDMVQ.NEDAQRL......RNAVVKDF.----------------safp..................
LCFC1_HUMAN/31-102                   ......................g-PKDGSQTEKTPS.ADQNQEQFEEHFVASSVGEMWQVVDMAQ.QEEDQSS......KTAAVHKH.SFHLSFCFSLASVMVF......................
A0A6J3F664_SAPAP/74-145              ......................g-PKDRSQTEKTTF.AEQNQEEFEEHFVASSVGEMWQAVDMVQ.QEDDETS......ETAAVHHH.PFHLGFCFSLASLTV-s.....................
A0A6I9JEY0_CHRAS/35-105              ......................d-PTESSQKERMPS.TEPDEEQLEEHFVASSVGEMWTLLDMAQ.QE-DEVT......ETAAVRDH.LLNLAFCMNLASIMVF......................
A0A151NL17_ALLMI/23-94               ...........vqgdkdklleeg------------S.PPAGWEEMEETFVASSTGEGMEVINMMQ.SDESQRL......RNSAVKDL.LLDLAISLNTGSIVLF......................
A0A6J0XCN6_ODOVR/83-154              .....................gl--DERSQKEKTPS.TDQDREQFEERFMASSVGEMWHVVDMAQ.QEDDKTS......EVAAIHDH.LFDFAFCFNLASIMVF......................
G5ALH7_HETGA/84-156                  ......................g-PEEGALEEKTPP.AEQGQEQYEEHFMASSEGEKWQVMDMAR.QEEDFTS......DTAAAQDHrLFDLALCFNLASIMVF......................
A0A3Q7WCV7_URSAR/77-148              .......................DPNEGSQNEEIPS.TDQDQEQFEEHFVASSVGEMWQVVDMAQ.QEDDKTS......DTAALRDH.LLDLAFCFNLASIMVF......................
#=GC seq_cons                        ......................h.sp-pSQpEKhPS.sDQsQEQFEEHFVASSVGEMWQVVDMAQ.QE-DpoS......csAAl+DH.LFcLAFCFNLASlMVF......................
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