GenomeNet

Database: Pfam
Entry: LPD29
LinkDB: LPD29
Original site: LPD29 
#=GF ID   LPD29
#=GF AC   PF18847.4
#=GF DE   Large polyvalent protein associated domain 29
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Burroughs AM;0000-0002-2229-8771
#=GF SE   Iyer LM
#=GF GA   27.00 27.00;
#=GF TC   28.50 28.90;
#=GF NC   26.70 26.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   28559295
#=GF RT   Polyvalent Proteins, a Pervasive Theme in the Intergenomic
#=GF RT   Biological Conflicts of Bacteriophages and Conjugative Elements.
#=GF RA   Iyer LM, Burroughs AM, Anand S, de Souza RF, Aravind L;
#=GF RL   J Bacteriol. 2017; [Epub ahead of print]
#=GF DR   INTERPRO; IPR041311;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is an alpha and beta fold domain with conserved polar
#=GF CC   residues that is found in polyvalent proteins of conjugative
#=GF CC   elements [1].
#=GF SQ   88
#=GS C5AP01_BURGB/32-128       AC C5AP01.1
#=GS A0A2T5ISE2_9GAMM/147-241  AC A0A2T5ISE2.1
#=GS A0A415DSW7_9BACT/92-179   AC A0A415DSW7.1
#=GS H1CZK9_9FIRM/4-69         AC H1CZK9.1
#=GS A0A231QZR5_9BACL/4-94     AC A0A231QZR5.1
#=GS A0A396MSZ0_9BACT/93-181   AC A0A396MSZ0.1
#=GS R7ETR8_9BACE/92-179       AC R7ETR8.1
#=GS A0A0U2X666_9ACTN/4-103    AC A0A0U2X666.1
#=GS A6L0Q7_BACV8/92-179       AC A6L0Q7.1
#=GS V8CVB7_9NOCA/4-104        AC V8CVB7.1
#=GS Q9PBQ4_XYLFA/6-99         AC Q9PBQ4.1
#=GS C5A9B2_BURGB/4-106        AC C5A9B2.1
#=GS A0A502G2W7_9PROT/153-239  AC A0A502G2W7.1
#=GS R7JNZ6_9BACT/92-179       AC R7JNZ6.1
#=GS A0A4V6QHF0_9MICO/5-105    AC A0A4V6QHF0.1
#=GS G2GF06_9ACTN/96-186       AC G2GF06.1
#=GS A0A0H3UZM4_9CAUD/6-103    AC A0A0H3UZM4.1
#=GS E7NS15_TREPH/84-190       AC E7NS15.1
#=GS D4M158_9FIRM/88-189       AC D4M158.1
#=GS V8CTV1_9NOCA/4-104        AC V8CTV1.1
#=GS A0A069D685_9BACE/332-419  AC A0A069D685.1
#=GS A0A4Q4Z8K3_9ACTN/32-126   AC A0A4Q4Z8K3.1
#=GS A0A268EC40_9BACI/107-199  AC A0A268EC40.1
#=GS M0QMC1_9ACTN/4-104        AC M0QMC1.1
#=GS W4HDW9_9RHOB/25-117       AC W4HDW9.1
#=GS A0A1B0V057_9CAUD/3-114    AC A0A1B0V057.1
#=GS R0C123_9FIRM/89-203       AC R0C123.1
#=GS S5WIU5_9CAUD/10-102       AC S5WIU5.1
#=GS A0A559IDB9_9BACL/6-95     AC A0A559IDB9.1
#=GS A0A3N2KSG6_9BACT/93-180   AC A0A3N2KSG6.1
#=GS T0IXT1_9SPHN/131-219      AC T0IXT1.1
#=GS A0A4P8J444_9BURK/6-99     AC A0A4P8J444.1
#=GS A0A0M8STW1_9ACTN/99-189   AC A0A0M8STW1.1
#=GS A0A2H4PB09_9CAUD/5-98     AC A0A2H4PB09.1
#=GS C5ANP5_BURGB/32-128       AC C5ANP5.1
#=GS W1J6T2_9GAMM/134-220      AC W1J6T2.1
#=GS A0A254VRQ0_9BURK/139-227  AC A0A254VRQ0.1
#=GS A0A0Q5N9X1_9MICO/5-105    AC A0A0Q5N9X1.1
#=GS A0A0V7ZCI7_9CYAN/5-96     AC A0A0V7ZCI7.1
#=GS A0A1Y5JU32_9BACL/4-94     AC A0A1Y5JU32.1
#=GS A0A060R8M2_9BACT/336-427  AC A0A060R8M2.1
#=GS A0A4S2T8M8_9ACTN/5-104    AC A0A4S2T8M8.1
#=GS A0A4R8XRM5_9MICO/5-105    AC A0A4R8XRM5.1
#=GS A0A411YDS4_9ACTN/7-105    AC A0A411YDS4.1
#=GS A0A374A076_9BACT/92-179   AC A0A374A076.1
#=GS A0A2V3PYH8_9BACT/83-220   AC A0A2V3PYH8.1
#=GS A0A6N9Q0D5_9BACL/2-123    AC A0A6N9Q0D5.1
#=GS A0A1M5DDJ0_9CLOT/19-133   AC A0A1M5DDJ0.1
#=GS A0A0F5JAQ1_9BACT/92-179   AC A0A0F5JAQ1.1
#=GS A0A0N1CVM6_9MICO/1-81     AC A0A0N1CVM6.1
#=GS A0A3N2N3B5_9BACT/93-180   AC A0A3N2N3B5.1
#=GS A0A0J8YDJ7_9GAMM/113-201  AC A0A0J8YDJ7.1
#=GS A0A368VL74_9BACL/8-98     AC A0A368VL74.1
#=GS A0A328EJF5_9BACT/4-92     AC A0A328EJF5.1
#=GS A0A1E3L172_9BACL/5-104    AC A0A1E3L172.1
#=GS A0A0D6PDG7_9PROT/6-125    AC A0A0D6PDG7.1
#=GS A0A133VQE9_9EURY/15-120   AC A0A133VQE9.1
#=GS A0A0M9YF38_9ACTN/96-190   AC A0A0M9YF38.1
#=GS A0A2S3ZSD2_ARTGL/5-98     AC A0A2S3ZSD2.1
#=GS A0A4R8Y313_9MICO/5-58     AC A0A4R8Y313.1
#=GS A0A7D4ALK1_9BACT/109-208  AC A0A7D4ALK1.1
#=GS A0A0A1H587_9BURK/4-97     AC A0A0A1H587.1
#=GS F8XMH6_9PROT/1-77         AC F8XMH6.1
#=GS A0A2T4YX88_9BACL/2-164    AC A0A2T4YX88.1
#=GS G9BW63_9CAUD/1-92         AC G9BW63.1
#=GS A0A060QDZ5_9PROT/138-225  AC A0A060QDZ5.1
#=GS W0EU49_9BACT/92-179       AC W0EU49.1
#=GS A0A174Q6D3_9BACE/92-179   AC A0A174Q6D3.1
#=GS A0A126P537_9BACT/109-208  AC A0A126P537.1
#=GS C5A9B5_BURGB/44-140       AC C5A9B5.1
#=GS A0A1N7HE10_9NOCA/4-104    AC A0A1N7HE10.1
#=GS D7V1G9_LISGR/59-148       AC D7V1G9.1
#=GS G2H045_9ENTR/119-221      AC G2H045.1
#=GS A0A3M9MH14_9MICO/15-103   AC A0A3M9MH14.1
#=GS A0A2J6MNG2_9BURK/129-220  AC A0A2J6MNG2.1
#=GS A6LIN6_PARD8/92-179       AC A6LIN6.1
#=GS R6DE15_9BACE/92-179       AC R6DE15.1
#=GS A0A5J5GGS6_9BACL/4-91     AC A0A5J5GGS6.1
#=GS A0A1Y4HKS8_9BACT/92-179   AC A0A1Y4HKS8.1
#=GS A0A430AW42_9ENTE/84-202   AC A0A430AW42.1
#=GS A0A0F5JT21_9BURK/7-100    AC A0A0F5JT21.1
#=GS A0A558BJY5_9MICO/109-208  AC A0A558BJY5.1
#=GS A0A0U5BIW8_9BACL/3-91     AC A0A0U5BIW8.1
#=GS E0UN47_GLOV7/10-99        AC E0UN47.1
#=GS A0A0S3F5W8_9SPHN/153-241  AC A0A0S3F5W8.1
#=GS A0A0H4KGK3_9BACI/105-197  AC A0A0H4KGK3.1
#=GS A0A0M0GC77_SPOGL/108-200  AC A0A0M0GC77.1
#=GS A0A1C5FKN5_9ACTN/99-195   AC A0A1C5FKN5.1
C5AP01_BURGB/32-128                  ..ltl---VDTAQLVQKILTEAFP...SCAFAVSVHSTGAg.....tLLDVAWTD.GPRA.DQ......V...............GRFVHPLQA........RRLAHGGRAVAVEH.............fTLTPVGYR...........TVRLAADRISLTRAF-s..........................................................................
A0A2T5ISE2_9GAMM/147-241             ....l-ETKEGAKLLKKTLTKLFP...DTKFSVTMSRGTAy.....gSVSVSWVD.GASY.DL......V...............DVIAQHFRG........NGYDGMSDSSYNLN..............-ALNADGQ...........IVDYGLGYVSISRGYS...........................................................................
A0A415DSW7_9BACT/92-179              ....q-HAPEIVELTRIWLKETYP...RYRFSVRRENYN-.......SIHVRLMK.ADFE.AF......-...............TRESGKVQ-........DEINHYCIESD--E..............SLTDRAKE...........VMMNICDFVMSYN---fd.........................................................................
H1CZK9_9FIRM/4-69                    ..esv---EKTAKVIAALLKEKFP...DVHFDVEAEYPNGt.....dRVVVRYTD.GPAP.AL......V...............DYYIDKFQT........--------------..............--------...........----------------mhplngnl...................................................................
A0A231QZR5_9BACL/4-94                ...es--GTETAKKIRAALRRAFP...GQTFSVRSSADS-.......-VLVNWED.GPFV.PD......V...............EDVLHAFQSy......eTRRSSGEDRREAVG.............yGWEGRRIV...........----GAQYLRTSRRL-s..........................................................................
A0A396MSZ0_9BACT/93-181              ..qrp---SEVADLFRKWVKETYP...GYKFSVRVRNYD-.......SITIQLLV.ADFA.PF......-...............TESSGITCN........CSVNHYYIERD--D..............DLTDRAKE...........VMQNVTDYIMSYN---yd.........................................................................
R7ETR8_9BACE/92-179                  ....q-HAPEIVELVRTWLKEIYP...RYKFSVRRENYN-.......SIYIKLMS.ADFE.AF......-...............TRESGKVQ-........DHINHYNIERN--P..............DLTDRAKE...........VMLNVCDFVMSYN---fd.........................................................................
A0A0U2X666_9ACTN/4-103               ....i-DTKDVAAELRNRLKSAFP...GVKFSVRKGTGTAs.....aWISVYWTD.GPCS.AD......V...............EELTRPMQG........AQFNGMEDRYESTD.............nTVTVTVKGr........kvTGKPLVDGINTHRGVS...........................................................................
A6L0Q7_BACV8/92-179                  ....q-HAPEIVALVRAWLKETYP...GYKFSVRRENCH-.......SIHIRLMK.ADFE.AF......-...............TKESGKVQGd......vNHYHIDSDK-----..............YLTDRAKD...........VMMNICDFIMSYN---fd.........................................................................
V8CVB7_9NOCA/4-104                   .....FTTKETAAELRKHLRATWP...TVKFSVRCGRGTAs.....aWLRVAWVD.GPAY.TQ......A...............QSEWVQFQS........AQFNGMTDSYDQLD.............dRLVCTDPAel.......peVRSYSCDGINGERAF-t..........................................................................
Q9PBQ4_XYLFA/6-99                    ....f-TCAETAKLVRKALKESFP...DIKFSVKSSNYSGe.....aSIRLKWID.GPNF.KQ......I...............KPISKCFKS........SYFDGSIDYKG---..............SIYHIMQG..........qIVRFGADFVLHHRDYS...........................................................................
C5A9B2_BURGB/4-106                   ....i-SRRETLSLVRKALHEAFP...QTTFTLQPSRSKGnaacgftLVWVKWID.GPSS.SQ......V...............HDVVSRFED........R-------------..............--------...........----------------iidwdrptpwsnqpkanhlldghavrfdvsffslkrtms....................................
A0A502G2W7_9PROT/153-239             ...hs--GKLAAANIRVQLRQSFP...GVRFSVRNTDHG-.......SIYVRWPG.GPEQ.KA......I...............ETVAMPFQG........GHFDGMDDSYKTAR..............SAWCEAFG...........----GAQY--------vvcrre.....................................................................
R7JNZ6_9BACT/92-179                  ....q-SAPEITELVRAWLKETYP...RYTFSVRKDGYS-.......SILIRLMK.ADFE.AF......-...............TRESGKVQ-........GDINHYNIQAS--D..............SLTDRAKE...........VMTNVRDFVMSYN---fd.........................................................................
A0A4V6QHF0_9MICO/5-105               ....i-STKDTAKLVRVALKNAFP...GVKFSVRMSTGTAs.....aWMNVSWSD.GPTD.RE......V...............SAVTSQYEG........RKFNGMTDGYDEQG..............SALVAFDGed......mprVVRYSCDGINTHRDYT...........................................................................
G2GF06_9ACTN/96-186                  ...ip--AKYAAVHLRKELRRVFP...GVKFSVRTGTGKRr.....gEITVTWTG.GPRR.TS......V...............SAVAAPLM-........ARFGPGDRRIA---..............RVDVTVGG...........----------------rrycgvpmvsaikln............................................................
A0A0H3UZM4_9CAUD/6-103               ..dvv----QVAKQIRKELKEKFP...FVKFSVRSSRYSGg.....sSVHVSWTD.FPTQ.ET......V...............EKIVNKYKQ........VRYDEYTGE-----..............--------...........----------------ilsggnlfviaqnkwsdelrnkietemknnys...........................................
E7NS15_TREPH/84-190                  ....l-RNKDITAIIRDYIKYVHP...TYKFSVSTTDNR-.......-IDIALME.HPIE.FTnr..elV...............EGYVKSLPPd.....erCFVPSLNDKLRRCQltkkq....reefiEWTIQTSG...........--RCELGFGALHKGL-c..........................................................................
D4M158_9FIRM/88-189                  ....r-TLKEVAQIVRTYVKEKYP...TYKFSVRTSYASMc.....kELHVTLKE.SPIP.--......I...............YKTFEELTN........DDFEKIGKSLF---..............PWNWVVDErmnflnasreeKEKIIRDSTNAYKN--vl.........................................................................
V8CTV1_9NOCA/4-104                   .....FTTKETAAELRKHLRATWP...TVKFSVRCERGTGs.....aWLRVAWVD.GPAN.LQ......A...............QNEWFGFQS........AQFNGMTDSYDQLD.............dRLVCTDPAel.......peVRSYSCDGINGVRA--ft.........................................................................
A0A069D685_9BACE/332-419             ....g--QKTAANNLRSLLKHKFP...ATKFSVRKHYYD-.......SYIVEWNE.GPSE.PQ......V...............KEITRLFVD........KGFDGMTDSSFSIT..............SPFIKRYG...........----GIGHISIDRN--is.........................................................................
A0A4Q4Z8K3_9ACTN/32-126              ....l-STKDTAALLRLELKRHFP...HGRFSVRVEHEWH......gWIRVRVTN.APPS.-L......V...............EEFTRQLEL........LRYDTFDDDHW-NH..............ALTVEEAGk........pcRMTNRVRS--------ikvewad....................................................................
A0A268EC40_9BACI/107-199             ....q-DAKEIAKEIRSHVRKRFP...QCKFSVRVPYYG-.......RISFDIKS.SPYE.KGs...vyL...............DAVLGYCNN........-LLDAYKHTYSAAD..............PYTDFAGV...........--YNFTGWVEISWEY-k..........................................................................
M0QMC1_9ACTN/4-104                   .....YTTKETAAALRTQLRTTWP...GVKFSVRCATGTAy.....gWMRVAWVD.GPDD.DQ......V...............RAVCNHYES........ERFDGMTDSYQQQP.............dPLVVTTPGel.......peMVRYSCCGINTERVY-t..........................................................................
W4HDW9_9RHOB/25-117                  ...vg--LTDTAKLIRGALKAKFP...RTKFSVRTSRFSGg.....tSIDISWTD.GPTA.EL......V...............DSITGPFQS........GGFDGMIDMAFSVG..............GW------...........----------------lypdgtaafretsgtegsa........................................................
A0A1B0V057_9CAUD/3-114               .....YITTEEVAEMRARLKAAFPlkeGWKFSLTKEHHS-.......SVNFRFMA.GPHE.FMa...fdVdqyshdpetpkcraqAEAMGKFK-........AVTNGSVNHYWIAD..............HWTPESAA...........ILQKASDIIHLHH-W-d..........................................................................
R0C123_9FIRM/89-203                  .....MSTTEISKAIKIYCKEKYP...TWKFSVTSKYFSGg.....sSIDISVME.APEQiFDla..acR...............KAYAEHLENe.....kmGYYGGRGLGMDIEKmla.......ddkmHWQLHSVRer.......dkEYFTEYGFSVLYD---vfa........................................................................
S5WIU5_9CAUD/10-102                  .ltpn----ESGKAIRAELKSKFP...NIKFSVKKDGAN-.......TYGVSWTD.GPNS.KE......V...............ENSIGRFRG........KTFNFNTGMVENIE..............YIVEYNGQ...........FYRSGVGYLFLKRTL-s..........................................................................
A0A559IDB9_9BACL/6-95                ...ic--GKETKRHIVEALKLVFP...GIKFSSRSSYDS-.......-VRVSWTD.GPLE.HD......V...............EKVLNRFQS........--YTRILDIDDRHE..............ATGYEWKG...........IVYVGARHLDASR---qls........................................................................
A0A3N2KSG6_9BACT/93-180              ....q-SSREIVEIIRNWLKETYP...KYKFSVRRDGYS-.......SIHVTLMT.ADFE.AF......-...............TKESGYIH-........CSINHYRVERE--Q..............GLTDRARE...........VMTNVKDFVMSYN---yd.........................................................................
T0IXT1_9SPHN/131-219                 ...as--GKLAAQNIRAELKAAFP...GIRFGVRKAHWG-.......SVSVTWTD.GPTE.KR......V...............GEIVNKYQG........GHFNGMDDIYERAD.............sPWTSVFGG...........-----SKYVFTSREFS...........................................................................
A0A4P8J444_9BURK/6-99                ....l-SCAETAKLVRQALKEAFP...GVKFGVRSSTYSGg.....aSISVRWED.GPNT.AQ......V...............EAITNRFKG........AYFDGSIDYKG---..............SVYHMMDG..........qQISFGADYIFTSRSYT...........................................................................
A0A0M8STW1_9ACTN/99-189              .lplp----RTAAHLRTLLSARFP...GVRFSVRARRGW-.......RLAVSWSG.GPLD.TE......V...............ATVAAPLL-........ADYATPGRRRAR--..............PVTVTRFGr........atH---------------gtplvdaitlnrr..............................................................
A0A2H4PB09_9CAUD/5-98                ....i-SVTDTAKIVRGELKKHFP...GVVFSVRSSSYSMg.....aSIDISWTD.GPIA.KA......V...............EAITGQFEG........SSFDSMQDM-KISR..............RGTWEGRE...........-VRWGSDYVTPTRKYS...........................................................................
C5ANP5_BURGB/32-128                  ..ltl---VDTAQLVQKILGEAFP...SCAFAVSVHSTGAg.....tLLDVAWTD.GPRA.DQ......V...............GRFVHPLQA........RRLAHGGRAVAVEH.............fTLTPVGYR...........TVRLAADRISLTRAF-s..........................................................................
W1J6T2_9GAMM/134-220                 .....YDTKEAIKNIRLDLKINFP...GIKFSVRMSKSS-.......-VYISWGSeSNIT.KE.....vV...............GNLLAKFKT........GSFDTYEDIHKNEY..............TPFNEVFG...........----SVDYIS------lrv........................................................................
A0A254VRQ0_9BURK/139-227             ...sc--GKLVAANIRKTLKKEWP...KVKFSVRKADYG-.......TVNVSWED.GPSE.DA......V...............KPFLSRHKA........GSFNSMEDYFEYQA..............TPFNQVFG...........----EARYIFAHRSI-s..........................................................................
A0A0Q5N9X1_9MICO/5-105               ....i-PTKDVAKLLRTELRAAFP...GVKFTVRCSTGTAs.....aWMNVSWAD.GPTT.GQ......V...............DEIAGRFEG........RKFNGMTDSYDHQG..............SVLIAGQGaa......mpeEVVYGCDGILTARTF-t..........................................................................
A0A0V7ZCI7_9CYAN/5-96                ....i-SAKEVAKHIRKDLKTKFP...SIKFSVRSETGT-.......-IRISYTD.GVPA.EE......I...............KEICTKYDS.......rRDYDPQYCDYRKSE..............PVEINGEM...........-LTTSVDYFFIDRNL-s..........................................................................
A0A1Y5JU32_9BACL/4-94                ...es--STETAKKIRAALRRAFP...GQTFSVRSSADS-.......-VSVSWED.GPFV.PD......V...............EDVLHAFQSy......eTRRSSGEDRREAVG.............yGWEGRRIV...........----GAQYLRTSRRL-s..........................................................................
A0A060R8M2_9BACT/336-427             .....YDQKVAANNLRVLLKRKFS...ETKFSVKKYYYD-.......SYTVSWVD.GPTV.GQ......V...............TEITRLFRN........EGFDGMTDSSYPII..............TPFNERYG...........----GIGSISAERKV-sehy.......................................................................
A0A4S2T8M8_9ACTN/5-104               ....v-ATKYVSAELRSRLKAEFP...GAKFSVRTGTGTGs.....aWISVSWTD.GPDT.EA......V...............DRIAAPLHG........AHWDGSTDSYVQTN.............nEVTVTVDGk........kvTGKPIVDGINTHRDFS...........................................................................
A0A4R8XRM5_9MICO/5-105               ....i-STKDTAKLVRVALKNAFP...GVKFSVRMSTGTAs.....aWMNVSWSD.GPTD.RE......V...............SAVTAIYEG........RKFNGMTDGYDDQG..............SALVAFDGed......mprVVRYSCDGINTHRDYT...........................................................................
A0A411YDS4_9ACTN/7-105               ..lap---TETAKLLRKHLRATFP...SAKFSVRTSKYAGg.....aSLRVSWTD.GPTD.DE......V...............RAATSLYEG........ADFDGMTDCKHYRD..............SILAHQDGt........veAVHHGADFIFTHRQLS...........................................................................
A0A374A076_9BACT/92-179              ..qmr---GEIVEIIRKWLKETYP...RYKFSVTQNGYR-.......SINIYLIK.ADFE.AF......-...............TKESGLIYKd......iNHYHIGTDR-----..............TITERARE...........VMLNVCDFTMSYN---yd.........................................................................
A0A2V3PYH8_9BACT/83-220              ....l-RTKDIAKIVREYLKEKYP...TYKFSITAPDYN-.......SLDIALLE.APQD.VI......V...............YDNLDDCQK........KYYNENTLNFDVNYyhi.......skddRLTELCRE...........ILQDAFDFAQTY----nfndsdaqidyfhtnfyngmsigkwdkpfkvvekqarikaer.................................
A0A6N9Q0D5_9BACL/2-123               ...sd--CVQVAKQIRKELKEVFP...YTKFSVRSSKYSMg.....sSITISWNN.MPLN.KE......V...............KEVTDKYAE.......iSYCEASGEILSG--..............--------...........----------------gnmyvstsynitnefreecekeiteeydqndyhdrlkyndeleeiisnkyh........................
A0A1M5DDJ0_9CLOT/19-133              .....MTTTEIAKTIRMYCKERYP...TWKFSVTSKYFSGg.....sEILICVME.APEQiFDlk..acR...............KAYTEHLENe.....kmGYYGGRGLGMNIEKmla.......edrmRWQLHRISdn.......ykEYFTEYAFSVLSDVY-s..........................................................................
A0A0F5JAQ1_9BACT/92-179              ..qmr---GEIVEIIRKWLKETYP...RYKFSVTQNGYR-.......SINIYLVK.ADFE.AF......-...............TKESGLIYKd......iNHYHIGTDR-----..............TITERARE...........VMLNVCDFTMSYN---yd.........................................................................
A0A0N1CVM6_9MICO/1-81                .....-------------------...-MKFSVRCSTGTAs.....aWMNVAWAD.GPTT.RQ......V...............GDITGRFEG........RKFNGITDSYDHQG..............SVLVAGEGea......mpeEVVYGCDGINTARTYS...........................................................................
A0A3N2N3B5_9BACT/93-180              ....q-SSREIVQIIRDWLKETYP...RYKFSVRRYNYS-.......SIYVTLMS.ADFE.AF......-...............TKESGYIH-........CSINHYRVERE--K..............GLTDRAHE...........VMTNVKDFVMSYN---yd.........................................................................
A0A0J8YDJ7_9GAMM/113-201             ....n-TTNLAAKNIRILLKKHFP...GVKFSVRKRDYT-.......CINVSWTD.GPTR.DA......V...............EAIVDKFQE........GSFNGMEDIYEYNH..............STFNRVYG...........----GVQYLFCSRDV-s..........................................................................
A0A368VL74_9BACL/8-98                ...ip--GKEAKKHILAALKLVFP...GFKFSLTSEYDS-.......-VLVSWTD.GPLT.PD......V...............QKVLNRFES.......yT------RVLWKTD..............--------...........----------------yteptgyewkgqlylgprylstvrrlsd...............................................
A0A328EJF5_9BACT/4-92                krqtp------AMLIKKDLKKVFP...GVKFSCKYDSFSGg.....dSVRIYWKG.GPLT.RA......V...............NKIAIQYKD........GYFDSMEDIYH---..............HINDKPYG...........---MTAKYIICN----rend.......................................................................
A0A1E3L172_9BACL/5-104               stpai-----AAKIARGILKKRFP...ATKFSVRANAYAL.......TLSVSWDD.GVMK.EH......V...............TQAIEWLEK........-DFVWENQEYNNSL..............--------...........----------------yityernlsperkaiihnrlvdekidtewfg............................................
A0A0D6PDG7_9PROT/6-125               .ikpa----ATAKLVRAALKKKFP...GIKFSVRIAGGS-.......-LNVSWVD.GPLA.SL......V...............DEVVQSYSS........TRFDCSIDMEYRVD..............NWLL----...........----------------pdgsaivaedrgtlgqkgccqpahnpqpegaklvrffygysfcrrefs...........................
A0A133VQE9_9EURY/15-120              ....l-GTKEIAKRIRKQLKKEFP...DCKFSVRIKRYSGg.....sSITVSFMK.ADRK.--......V...............KMDFDKIPQ........GWFNRYLDIRSIEDlrklqnedyhqlnqHTLKQEYG...........--GHWCNGVFLTRQ--gh.........................................................................
A0A0M9YF38_9ACTN/96-190              ...lt--MRATAEYLRRLLRRTFP...GVKFSVRCGRGHGmq...ryEITVGWSG.GPSR.TA......V...............ATVTAPLL-........AQYGNPEQC-----..............--------...........----------------rpawiavtvggrrhfgepsasaihlnr................................................
A0A2S3ZSD2_ARTGL/5-98                ....v-SATDTAKLVKRTLKAQFP...DTKFSVRTLKYAGg.....aTVDVEWVH.GPTT.PA......V...............DAIVKDFEG........TAPDATGDFSD---..............PITHTKDG..........qQIHYGARHIHTRR---mit........................................................................
A0A4R8Y313_9MICO/5-58                ....i-STKDTAKLVRVALKNAFS...GVKFSVRMSTGTAs.....aWMNVSWSD.GPTD.R-......-...............---------........--------------..............--------...........----------------edmprvv....................................................................
A0A7D4ALK1_9BACT/109-208             .....YTTAGTAQLIREALKKAFP...TVKFSVTSSSFANg.....sSVDIAYTD.GPSS.KQ......V...............ERVYAPFSS........GHFNSQEDLYEYHQ.............ePTAINEAGq........laRVSYGAKYISDRRSY-s..........................................................................
A0A0A1H587_9BURK/4-97                ....f-STAETAAIIRKSLKEAFA...GIKFSVRSSVYSGg.....sSISVRWTD.GPSE.EQ......V...............RGVVGHLCG........GYFDGSIDYAG---..............SVYHMQEG..........kEIRLENDHLFFNRDH-s..........................................................................
F8XMH6_9PROT/1-77                    .....------------MLKRAFP...TVKFSVKKSSHS-.......TVDVSWTD.GPIT.SQ......V...............EQYTRQFEA........GRFNGMEDIYDYKR.............tPWNTLFGA...........-----IDMILVHRN--ts.........................................................................
A0A2T4YX88_9BACL/2-164               ...ak--ATEVAKKIRKVLKEQFP...GTKFSVRTDQYSMg.....aSIIIKWTN.FPTE.QT......V...............DKVVRPYEQvsrdpitgDILSGGNLHISAVN..............KWTSELRE...........----------------eiekemphhikrsdleyyryfretsekvyeryrerieaptnrgqvmkdpegavtirqkmalhratglnttewelt
G9BW63_9CAUD/1-92                    .....MNNQQIIHQAKLILRDTYR...HARFVVTVEGSD-.......-IIVSWTD.GPTE.KS......V...............MGFISYLSAni...kpnRTYTEQQ-------..............--------...........----------------eeadiweflvnnsqiwefvvnddaka.................................................
A0A060QDZ5_9PROT/138-225             ..rdg---ALAAKNIRKLLKAAFK...TTKFSVRKSEYG-.......CIYVRWSE.GPSE.DE......V...............SEITDRFKT........GTFDHYSDCARQED.............tPWSKSFGG...........-----AEYVFTSR---ae.........................................................................
W0EU49_9BACT/92-179                  ....q-SAPEITELVRTWLKETYP...RYTFSVRRDGYS-.......SILVRLMK.ADFE.AF......-...............TKESGKVQ-........GDINHYNIQAS--D..............SLTDRAKE...........VMTNVRDFVMSYN---fd.........................................................................
A0A174Q6D3_9BACE/92-179              ....q-SAPEITELVRAWLKETYP...RYTFSVRRDGYN-.......SILIRLMK.ADFE.AF......-...............TRESGKVQ-........GDINHYNIQAS--D..............SLTDRAKE...........VMTNIRDFVMSYN---fd.........................................................................
A0A126P537_9BACT/109-208             ...yt--VAGTAQLIREALKVAFP...EVKFSVTSDSFANg.....tSVRIAYTD.GPTR.KQ......V...............EQVYAAFES........GQYNSQEEIYEYRR.............ePMTIDNSGq........lfRMSYGAKYISESRSYS...........................................................................
C5A9B5_BURGB/44-140                  ..lsl---VETAQLVQSILTESFG...NTRFYVKTQQTGNh.....tRIHVEWVD.GPTE.QQ......V...............NKILLPLQSs.....tpGTFGGLTPV----Eh............fRITPTGPQ...........KLSLSADRISVKRGF-s..........................................................................
A0A1N7HE10_9NOCA/4-104               .....FTTKQTAAEIRKHLRATWP...GVKFSVRCDRGTAs.....sWIRVSWTD.GPTD.QQ......V...............RHETHQFQG........AQFNGMTDSYDDLG.............eALVCTNPAel.......peVRRYYCDGINTSRDI-s..........................................................................
D7V1G9_LISGR/59-148                  ..psi-----TAKKVKGALQSAFPdlpKKHFSVQVNRLG-.......DIDVKWVD.YPAK.KT......V...............EEITKGYQS........ATYDKELE------..............--------...........----------------tdivhgyeengqriqgagyitlsgtl.................................................
G2H045_9ENTR/119-221                 .eeel-----VICNLRIELQACFP...DVKFTVRKVLDS-.......CVTVCWED.GVPD.DQ......V...............GYIIGKYQN.......gIIFGKCQNRII---..............--------...........----------------qcpfhdvfggvsyvvhdrhysdafvqyaidrlrdkys......................................
A0A3M9MH14_9MICO/15-103              .ltpv----ETAKLIRRALRAAHP...HTRFHLVCSRGTGy.....gYMSLQWVA.GPST.AA......V...............RTTVEPFLS........EVA-----------..............--------...........----------------sdepddavrrlpvpytckgidlirleke...............................................
A0A2J6MNG2_9BURK/129-220             ....y-SGRLAAANIRIELKRAFP...GVKFSVRMTHYG-.......AVSVHWTD.GPRQ.AE......V...............EALCRRYKA........GRFNSMEDIYEHAV.............qPWHHVFGG...........----------------leylsvsreesaal.............................................................
A6LIN6_PARD8/92-179                  ....q-HAPEIVELIRAWFRETYP...GYKFSVRRENCH-.......SIHIRLMK.ADFE.AF......-...............TKESGKVQG........-DVNHHHIASD--K..............SLTDRAKD...........VMMNIYDFIMSYN---fd.........................................................................
R6DE15_9BACE/92-179                  ....q-HAPEIVELVRTWLKETYP...RYRFSVRRENYN-.......SIYIKLMS.ADFE.AF......-...............TKESGKVQ-........DTINHYNIEWN--P..............DLTDRAKE...........VMMNVCDFVMSYN---fd.........................................................................
A0A5J5GGS6_9BACL/4-91                .tqia----LTAQALRQALKEAFP...LTKFSVRSSAGC-.......AINVSWTD.LPSV.AA......V...............EAITDKYKN........VSYDHHT-------..............--------...........----------------geilsgantyvfcnveyspeftaeve.................................................
A0A1Y4HKS8_9BACT/92-179              ....q-HAPEIVGLVRTWLKETYP...KYRFSVRRSGYS-.......SINIRLMT.ADFE.AF......-...............TKESGKVQGd......iNHYHIASDM-----..............SLTDRAKE...........VMTNVRDFVMSYN---fd.........................................................................
A0A430AW42_9ENTE/84-202              ....l-GTKEIAANLRKYVKEVYP...TWKFSITCQFYSGg.....sSISVAAME.APYEiLE......R...............DKIKDNCYV........DFYDHEE-------..............--------...........----------------gedfkagginidihrmrdreempilndfgyevlndvfeqlmsyryddsdgmid......................
A0A0F5JT21_9BURK/7-100               ....l-SCADTAKLVRASLKEAFP...QCRFSVRSSTYAGg.....aSISIRWTD.GPNH.TQ......V...............EFITGKFAG........SYFDGSIDYKG---..............SIFHLLDG..........aPVHMGADSIHLSRSYS...........................................................................
A0A558BJY5_9MICO/109-208             .....YTTAGTAQLIREALKKAFP...AVKFSVTSSTFANg.....sSVDIAYTD.GPSS.KQ......V...............EQVYAPFIS........GRFNSQEDMYEYHR.............ePTAINEAGq........laRVSYGAKYISDRRSY-s..........................................................................
A0A0U5BIW8_9BACL/3-91                ..dvv----EIAKQIRTVLKKEFP...ATKFSVRSERYSLg.....aSIRVSWDG.LPST.AT......V...............STITDSFAK.......vRYCDATGEIL----..............--------...........----------------sggnmfitaqasetdevraai......................................................
E0UN47_GLOV7/10-99                   ...ve--VKEIAKEVKLELSQAFQ...GVKFSVKSTLDK-.......-ITIAWTD.GPTQ.KE......V...............LPIAKKYLG........-IKNNYADDTRLYE..............PVKFRGKM...........-VSTYLEYVFTDRK--es.........................................................................
A0A0S3F5W8_9SPHN/153-241             ...ss--GKLAAQNIRAELKAAFP...GIRFSVRKESWG-.......SIRISWTD.GPTE.SS......V...............NEIVKKYQG........GSFNGMDDIYEYAG.............sPWTTVFGG...........-----SKYVFTSRDH-s..........................................................................
A0A0H4KGK3_9BACI/105-197             ....q-EAKVIAKEIRAHIKKRFP...QCKFSVTVPYYG-.......KINFTIKS.SPFE.KGsvylnaV...............KEYCV----........NLLNAYRHCYSPSD..............PYTDYAGS...........--YNFYGYVEIDWEY-t..........................................................................
A0A0M0GC77_SPOGL/108-200             ....q-DCKEIAKEIRSHIKKRFP...QCKFSVRVPYYG-.......KINFEIKS.SPFE.KGs...lyL...............NAIKGYCES........-LLNAYKHTYSEAD..............PYTDYAGV...........--HNFYGYVEIDWEYT...........................................................................
A0A1C5FKN5_9ACTN/99-195              ....v-STRVTAIHLRRMLRAAFP...GVKFSVRCGRRDAkgl.tpfEITVTWAG.GPTR.TA......V...............ATVTSPLL-........ATYGTAEERRAR--..............RISVTTDG...........RTH-------------ngfpsvyaihlrr..............................................................
#=GC seq_cons                        .......st-sAphlRthLKcsFP...ssKFSVRssphs........plpVsWs-.GPtp.tt......V...............pphssphps........spasshpctht..t..............shh.th.t................hphl...p..............................................................................
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