#=GF ID   M3
#=GF AC   PF09213.16
#=GF DE   M3
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1mkf
#=GF GA   25.00 25.00;
#=GF TC   78.20 676.20;
#=GF NC   18.10 17.40;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 8 -Z 90746521 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12419245
#=GF RT   Structural basis of chemokine sequestration by a herpesvirus
#=GF RT   decoy receptor. 
#=GF RA   Alexander JM, Nelson CA, van Berkel V, Lau EK, Studts JM, Brett
#=GF RA   TJ, Speck SH, Handel TM, Virgin HW, Fremont DH; 
#=GF RL   Cell. 2002;111:343-356.
#=GF DR   INTERPRO; IPR015296;
#=GF DR   SCOP; 1mkf; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Members of this family of viral chemokine binding proteins adopt
#=GF CC   a structure consisting of two different beta-sandwich domains of
#=GF CC   partial topological similarity to immunoglobulin-like folds.
#=GF CC   They bind with the CC-chemokine MCP-1, acting as cytokine decoy
#=GF CC   receptors [1].
#=GF SQ   2
#=GS O41925_MHV68/38-404  AC O41925.1
#=GS P89653_MHV68/22-397  AC P89653.1
O41925_MHV68/38-404             SGVSTQSVDLSQIKRGDEIQAH------CLTPAETEVTECAGILKDVLSKNLHELQGLCNVKNKMGVPWVSVEELGQEIITGRLPFPSVGGTPVNDLVRVLVVAESNTPEETPEEEFYAYVELQTELYTFGLSDDNVVFTSDYMTVWMIDIPKSYVDVGMLTRATFLEQWPGAKVTVMIPYSSTFTWCGELGAISEESAPQPSLSARSPV---CKNSARYSTSK-FCEVDGCTAETGMEKMSLLTPF---GGPPQQAKMNTCPCYYKYS-VSPLPAMDHLILADLAGLDSLTSPVYVMAAYFDSTHENPVRPSSKLYHCALQMTSHD-GVWTS--TSSEQCPIRLVEGQSQNVLQVRVAPTSMPNLVGVSLMLEGQQYRLEYFG
P89653_MHV68/22-397             SVVNIETYPFPEDDTKEDMRDYLFLVQNCLLQDNFNATYCSDSFEKLDKRSHFTLPDTCNVKTTFLVNY-NRHKYGIFKFESRLPLPTMASATSGRVIKVLVLAEAG----RPWKRHWANLAMVTYSNVVRLTDFNAKFRTRFSRIWSVTLDRHEVDLDLTFAGFLFAAPESVQLTLLMDYVPTFTWCGQI-SLNDPDLPVPSFQAIRTLPVMCFPMWRYLNGQDFHHQDGCHQESKWWNPTHIIPRLNPGTESHNITLNTCVCHVKYNDLQELDTAHRIKILTISNFFGFYKPLYVLVTYFGSSDVNVEGQAPPLQYCVVFIHRGNYGFFRTRQRGDPDCPCHFSLGRDEIVLVGHYV--DVKRIVGITIFFDGQEHRISYLG
#=GC seq_cons                   SsVshpohshsp.cpt--hpsa......CLh.sphpsT.Cus.hccl.p+shapL.shCNVKsphhVsa.shcchG..hhpuRLPhPohuusssscll+VLVlAEus....pP.ccaaA.lth.T...shtLoD.NshFpoca.plW.lsls+p.VDlshhhtuhhhtt..usplTlhhsYssTFTWCGpl.uls-.shP.PShpAhpsl...Chs.hRY.sup.Fpc.DGCptEoth.p.ohlhPh...Gs.spphphNTCsCahKYs.lp.Lsshc+lhlhslush.uhhpPlYVhssYFsSoc.Ns.t.us.L.aCsl.hppts.Ghapo..pus.pCPh+hs.Gpsp.VL.s+hs..sh.plVGlolhh-GQpaRlpYhG
//