GenomeNet

Database: Pfam
Entry: Mce4_CUP1
LinkDB: Mce4_CUP1
Original site: Mce4_CUP1 
#=GF ID   Mce4_CUP1
#=GF AC   PF11887.11
#=GF DE   Cholesterol uptake porter CUP1 of Mce4, putative
#=GF PI   DUF3407;
#=GF AU   Assefa S;0000-0003-2178-533X
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   PFAM-B_3559 (release 23.0)
#=GF GA   32.60 32.60;
#=GF TC   32.60 32.60;
#=GF NC   32.50 32.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   18955493
#=GF RT   The actinobacterial mce4 locus encodes a steroid transporter.
#=GF RA   Mohn WW, van der Geize R, Stewart GR, Okamoto S, Liu J,
#=GF RA   Dijkhuizen L, Eltis LD;
#=GF RL   J Biol Chem. 2008;283:35368-35374.
#=GF DR   INTERPRO; IPR024516;
#=GF DR   TC; 3.A.1;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Mce4_CUP1 is a family of putative Mce4 transporters of
#=GF CC   cholesterol.  The domain is found associated with Pfam:PF02470.
#=GF CC   The full TCDB classification for this family in conjunction with
#=GF CC   PF02470 is TC:3.A.1.27.4.
#=GF SQ   8090
#=GS A0A541BSE3_9NOCA/116-379  AC A0A541BSE3.1
#=GS A0A6I3L5W8_9NOCA/132-278  AC A0A6I3L5W8.1
#=GS A0A419HSY3_9PSEU/111-318  AC A0A419HSY3.1
#=GS A0A6H9YY23_9ACTN/118-341  AC A0A6H9YY23.1
#=GS A0A3A5H6P3_9ACTN/115-316  AC A0A3A5H6P3.1
#=GS A0A2T5W5V8_9ACTN/118-336  AC A0A2T5W5V8.1
#=GS A0A0N0AY35_9ACTN/122-333  AC A0A0N0AY35.1
#=GS A0A316TG16_9ACTN/116-332  AC A0A316TG16.1
#=GS X8B864_MYCAV/114-313      AC X8B864.1
#=GS A0A4R4NTZ9_9ACTN/116-319  AC A0A4R4NTZ9.1
#=GS A0A1D8T7P2_9NOCA/122-343  AC A0A1D8T7P2.1
#=GS B2HQG9_MYCMM/112-310      AC B2HQG9.1
#=GS K5BC26_MYCHD/113-330      AC K5BC26.1
#=GS A0A3N6E9J3_9ACTN/138-351  AC A0A3N6E9J3.1
#=GS A0A5R9MB94_9ACTN/120-320  AC A0A5R9MB94.1
#=GS A0A5S9Q0S8_MYCVN/115-344  AC A0A5S9Q0S8.1
#=GS A0A0M8TLY6_9ACTN/123-340  AC A0A0M8TLY6.1
#=GS A0A4R2QTD0_9PSEU/128-347  AC A0A4R2QTD0.1
#=GS A0A6G9YDX5_9NOCA/116-304  AC A0A6G9YDX5.1
#=GS A0A2A7N0U5_MYCAG/116-325  AC A0A2A7N0U5.1
#=GS A0A5B1LFJ5_9ACTN/120-336  AC A0A5B1LFJ5.1
#=GS A0A231H1L0_9NOCA/114-267  AC A0A231H1L0.1
#=GS A0A3B7D678_9ACTN/157-327  AC A0A3B7D678.1
#=GS A0A4R4L9W9_9ACTN/117-316  AC A0A4R4L9W9.1
#=GS A0A5S9PM12_MYCVN/124-315  AC A0A5S9PM12.1
#=GS A0A1N7CSI1_9NOCA/156-330  AC A0A1N7CSI1.1
#=GS A0A2A7N695_MYCAG/126-295  AC A0A2A7N695.1
#=GS A0A0Q5QF13_9NOCA/115-332  AC A0A0Q5QF13.1
#=GS A0A4V2XLB8_9ACTN/120-330  AC A0A4V2XLB8.1
#=GS A0A1Q5LRJ5_9ACTN/118-335  AC A0A1Q5LRJ5.1
#=GS A0A5C8NIR6_9ACTN/120-329  AC A0A5C8NIR6.1
#=GS A0A5A7WLI0_9MYCO/124-344  AC A0A5A7WLI0.1
#=GS A0A2U3P641_9MYCO/118-330  AC A0A2U3P641.1
#=GS A0A132T6H0_9MYCO/116-330  AC A0A132T6H0.1
#=GS A0A238WPS2_9PSEU/109-324  AC A0A238WPS2.1
#=GS D1A3I8_THECD/131-313      AC D1A3I8.1
#=GS A0A2U3P2Z3_9MYCO/116-328  AC A0A2U3P2Z3.1
#=GS A0A3M2KZZ8_9NOCA/117-331  AC A0A3M2KZZ8.1
#=GS A0A495XH61_9PSEU/112-314  AC A0A495XH61.1
#=GS A0A1X0HHM1_9MYCO/120-310  AC A0A1X0HHM1.1
#=GS A0A0I9Z0A2_9MYCO/118-396  AC A0A0I9Z0A2.1
#=GS A1U940_MYCSK/126-295      AC A1U940.1
#=GS W5TQP8_9NOCA/128-349      AC W5TQP8.1
#=GS V4I9U9_9ACTN/128-334      AC V4I9U9.1
#=GS A0A1E3RYF7_9MYCO/119-335  AC A0A1E3RYF7.1
#=GS A1UM36_MYCSK/118-330      AC A1UM36.1
#=GS H0QV80_9ACTN/124-341      AC H0QV80.1
#=GS A0A419HB84_9PSEU/128-368  AC A0A419HB84.1
#=GS A0A1Y5XF48_KIBAR/115-322  AC A0A1Y5XF48.1
#=GS A0A4Q7V228_9PSEU/115-319  AC A0A4Q7V228.1
#=GS A0A177YMF8_9NOCA/119-319  AC A0A177YMF8.1
#=GS A0A429G868_9ACTN/124-342  AC A0A429G868.1
#=GS A0A2U3PAA4_9MYCO/127-301  AC A0A2U3PAA4.1
#=GS A0A1I5QZG7_9PSEU/119-303  AC A0A1I5QZG7.1
#=GS R4SXH9_9PSEU/120-331      AC R4SXH9.1
#=GS A0A4R8R8A1_9MYCO/119-319  AC A0A4R8R8A1.1
#=GS A0A0U3TCX3_9ACTN/127-322  AC A0A0U3TCX3.1
#=GS A0A6G6W861_9ACTN/119-335  AC A0A6G6W861.1
#=GS A0A6I4M735_9ACTN/119-302  AC A0A6I4M735.1
#=GS A0A1H5Y0Z8_9ACTN/128-328  AC A0A1H5Y0Z8.1
#=GS A0A5B8EK82_9ACTN/122-302  AC A0A5B8EK82.1
#=GS A0A6H0CVW8_9ACTN/122-344  AC A0A6H0CVW8.1
#=GS A0A543AZJ3_9ACTN/114-332  AC A0A543AZJ3.1
#=GS A0A5B1MBU9_9ACTN/127-346  AC A0A5B1MBU9.1
#=GS A0A4T0VCJ2_9ACTN/116-311  AC A0A4T0VCJ2.1
#=GS A0A3A4KUX4_9NOCA/114-331  AC A0A3A4KUX4.1
#=GS A0A1X0H7K4_9MYCO/128-346  AC A0A1X0H7K4.1
#=GS A0A4R4P4W0_9ACTN/111-303  AC A0A4R4P4W0.1
#=GS A0A5D0NXC3_9ACTN/117-324  AC A0A5D0NXC3.1
#=GS A0A557XM81_9MYCO/115-305  AC A0A557XM81.1
#=GS A0A2R5HCT3_9MYCO/126-304  AC A0A2R5HCT3.1
#=GS A0A3S4VL78_MYCCI/126-346  AC A0A3S4VL78.1
#=GS A0A514JLG5_9ACTN/121-335  AC A0A514JLG5.1
#=GS A0A1A1XCQ8_9MYCO/115-327  AC A0A1A1XCQ8.1
#=GS A0A6B3HV47_9ACTN/121-333  AC A0A6B3HV47.1
#=GS G7CDL4_MYCT3/130-319      AC G7CDL4.1
#=GS V5XAY2_MYCNE/125-326      AC V5XAY2.1
#=GS L7LCT5_9ACTN/121-338      AC L7LCT5.1
#=GS A0A0B8NJT9_9NOCA/125-313  AC A0A0B8NJT9.1
#=GS G7CGT7_MYCT3/116-316      AC G7CGT7.1
#=GS I4BHF2_MYCCN/125-306      AC I4BHF2.1
#=GS B2HMU2_MYCMM/114-302      AC B2HMU2.1
#=GS A0A0B8NHK4_9NOCA/133-353  AC A0A0B8NHK4.1
#=GS A0A5S4FLY6_9ACTN/116-330  AC A0A5S4FLY6.1
#=GS A0A2S2C816_9NOCA/124-313  AC A0A2S2C816.1
#=GS A0A1X1TNC6_9MYCO/128-347  AC A0A1X1TNC6.1
#=GS A0A1I5J2D9_9PSEU/122-332  AC A0A1I5J2D9.1
#=GS A0A1Q9TAS1_9ACTN/114-303  AC A0A1Q9TAS1.1
#=GS A0A5B2XP68_9PSEU/118-328  AC A0A5B2XP68.1
#=GS A0A3S4RKZ2_MYCCI/127-364  AC A0A3S4RKZ2.1
#=GS A0A222VU33_9PSEU/115-334  AC A0A222VU33.1
#=GS A0A1A1YFM9_9MYCO/117-334  AC A0A1A1YFM9.1
#=GS A0A1X0DCP1_9MYCO/133-352  AC A0A1X0DCP1.1
#=GS A0A4V2RH14_9ACTN/122-341  AC A0A4V2RH14.1
#=GS A0A0M8QMG2_9ACTN/129-335  AC A0A0M8QMG2.1
#=GS A0A448IAL4_MYCCI/124-320  AC A0A448IAL4.1
#=GS A1UD52_MYCSK/129-313      AC A1UD52.1
#=GS L7L5Y6_9ACTN/110-317      AC L7L5Y6.1
#=GS A0A1E3R7X2_9MYCO/117-310  AC A0A1E3R7X2.1
#=GS G7GUZ9_9ACTN/116-360      AC G7GUZ9.1
#=GS D9UWI5_9ACTN/117-340      AC D9UWI5.1
#=GS A3TH70_9MICO/123-340      AC A3TH70.1
#=GS A0A4R9F085_9ACTN/111-318  AC A0A4R9F085.1
#=GS A0A1A3BMG2_9MYCO/130-348  AC A0A1A3BMG2.1
#=GS A0A6I3KR13_9NOCA/122-309  AC A0A6I3KR13.1
#=GS A0A1A1XBK0_9MYCO/122-232  AC A0A1A1XBK0.1
#=GS A0A4R4MNH7_9ACTN/120-303  AC A0A4R4MNH7.1
#=GS A0A6I3KR27_9NOCA/119-401  AC A0A6I3KR27.1
#=GS A0A2S2C2G7_9NOCA/121-343  AC A0A2S2C2G7.1
#=GS F5YUN6_MYCSD/102-315      AC F5YUN6.1
#=GS A0A1H9RXG5_9PSEU/116-328  AC A0A1H9RXG5.1
#=GS A0A1W0B213_9NOCA/115-258  AC A0A1W0B213.1
#=GS A0A0Q8E607_9ACTN/117-305  AC A0A0Q8E607.1
#=GS A0A0D1LMQ1_9MYCO/116-393  AC A0A0D1LMQ1.1
#=GS A0A1E3S393_9MYCO/200-318  AC A0A1E3S393.1
#=GS A0A1I6A4N3_9PSEU/114-327  AC A0A1I6A4N3.1
#=GS A1TDX8_MYCVP/121-338      AC A1TDX8.1
#=GS A0A1X1RAG1_9MYCO/125-300  AC A0A1X1RAG1.1
#=GS A0A1X0GQB4_9MYCO/118-352  AC A0A1X0GQB4.1
#=GS A0A1Q4HBP3_9MYCO/119-313  AC A0A1Q4HBP3.1
#=GS A0A1N7D3U4_9NOCA/144-367  AC A0A1N7D3U4.1
#=GS A0A1X0D3B6_9MYCO/125-284  AC A0A1X0D3B6.1
#=GS A0A542DR89_9PSEU/123-345  AC A0A542DR89.1
#=GS A0A5C8NF29_9ACTN/119-337  AC A0A5C8NF29.1
#=GS A0A4R1AG46_9ACTN/121-341  AC A0A4R1AG46.1
#=GS X8FI11_MYCUL/1-130        AC X8FI11.1
#=GS A0A1J7BBS5_9ACTN/127-326  AC A0A1J7BBS5.1
#=GS A0A117I7X4_9MYCO/124-345  AC A0A117I7X4.1
#=GS A0A2A7N639_MYCAG/128-346  AC A0A2A7N639.1
#=GS A0A2N3YHJ1_9MICO/135-346  AC A0A2N3YHJ1.1
#=GS A0A1X1R453_9MYCO/118-323  AC A0A1X1R453.1
#=GS F5YVM7_MYCSD/121-301      AC F5YVM7.1
#=GS A0A1A1YAT4_9MYCO/121-305  AC A0A1A1YAT4.1
#=GS A0A0N9XUV3_MYCFO/115-311  AC A0A0N9XUV3.1
#=GS A0A1X1RID2_MYCFA/129-257  AC A0A1X1RID2.1
#=GS A0A4R5C624_9ACTN/119-339  AC A0A4R5C624.1
#=GS A0A1A3Q4R9_9MYCO/130-349  AC A0A1A3Q4R9.1
#=GS A0A1I1AJS3_9PSEU/117-311  AC A0A1I1AJS3.1
#=GS A0A3D9SI18_9ACTN/118-327  AC A0A3D9SI18.1
#=GS I4BHF4_MYCCN/116-310      AC I4BHF4.1
#=GS A0A448IDY8_MYCCI/118-332  AC A0A448IDY8.1
#=GS A0A2S2BSJ8_9NOCA/117-339  AC A0A2S2BSJ8.1
#=GS A0A660CFR4_9PSEU/119-335  AC A0A660CFR4.1
#=GS A0A0B8NAW9_9NOCA/121-312  AC A0A0B8NAW9.1
#=GS A0A4P6UCM2_9NOCA/119-337  AC A0A4P6UCM2.1
#=GS A0A1A3NEA7_MYCAS/116-312  AC A0A1A3NEA7.1
#=GS A0A132MYF4_9ACTN/119-376  AC A0A132MYF4.1
#=GS I4BM08_MYCCN/119-332      AC I4BM08.1
#=GS A0A1G8REV3_9NOCA/122-336  AC A0A1G8REV3.1
#=GS A0A5S9NH14_MYCVN/117-334  AC A0A5S9NH14.1
#=GS A0A0D5AJD8_9NOCA/117-338  AC A0A0D5AJD8.1
#=GS A0A1H0CWA4_9ACTN/124-332  AC A0A1H0CWA4.1
#=GS A0A1X0DG19_9MYCO/125-342  AC A0A1X0DG19.1
#=GS A0A4U0P3E5_9ACTN/119-333  AC A0A4U0P3E5.1
#=GS A0A6I3KV18_9NOCA/133-354  AC A0A6I3KV18.1
#=GS A0A1C5CK46_9ACTN/138-359  AC A0A1C5CK46.1
#=GS A0A3E0GWG4_9PSEU/118-327  AC A0A3E0GWG4.1
#=GS A0A5P8ZVW9_9MYCO/118-313  AC A0A5P8ZVW9.1
#=GS A0A0I9Y9S7_9MYCO/115-318  AC A0A0I9Y9S7.1
#=GS A0A1I4RT73_9PSEU/117-339  AC A0A1I4RT73.1
#=GS A0A378THD1_9MYCO/118-321  AC A0A378THD1.1
#=GS A0A1Q4HL26_9MYCO/125-308  AC A0A1Q4HL26.1
#=GS A0A1Q5BE60_9ACTN/118-347  AC A0A1Q5BE60.1
#=GS A0A059MNB2_9NOCA/121-342  AC A0A059MNB2.1
#=GS A0A1Q4HDG6_9MYCO/125-333  AC A0A1Q4HDG6.1
#=GS A0A6L7ESG0_9ACTN/115-311  AC A0A6L7ESG0.1
#=GS A0A4R4MNF2_9ACTN/129-313  AC A0A4R4MNF2.1
#=GS A0A5A7S652_9NOCA/119-346  AC A0A5A7S652.1
#=GS L7LGN5_9ACTN/131-366      AC L7LGN5.1
#=GS A0A5S9QYC9_MYCVN/112-360  AC A0A5S9QYC9.1
#=GS A0A1J4NBC3_9ACTN/113-310  AC A0A1J4NBC3.1
#=GS A0A1C4TGA7_9ACTN/137-351  AC A0A1C4TGA7.1
#=GS A0A1X0GYB7_9MYCO/118-334  AC A0A1X0GYB7.1
#=GS A0A231H746_9NOCA/117-333  AC A0A231H746.1
#=GS A0A6F8YQ59_9ACTN/114-334  AC A0A6F8YQ59.1
#=GS A0A3E0GUQ8_9PSEU/113-316  AC A0A3E0GUQ8.1
#=GS A0A2G7F8K2_9ACTN/203-409  AC A0A2G7F8K2.1
#=GS L7KFR7_9ACTN/121-322      AC L7KFR7.1
#=GS A0A1I5E7U9_9ACTN/120-282  AC A0A1I5E7U9.1
#=GS A0A1A3J701_9MYCO/125-342  AC A0A1A3J701.1
#=GS K5BBI0_MYCHD/122-284      AC K5BBI0.1
#=GS A0A132T7T6_9MYCO/122-340  AC A0A132T7T6.1
#=GS A0A1I1A079_9PSEU/120-342  AC A0A1I1A079.1
#=GS G7CJS1_MYCT3/117-302      AC G7CJS1.1
#=GS A0A1X0HGU2_9MYCO/105-324  AC A0A1X0HGU2.1
#=GS W5TGE7_9NOCA/127-347      AC W5TGE7.1
#=GS A0A0M8T1Q9_9ACTN/113-323  AC A0A0M8T1Q9.1
#=GS A0A4R4XKM4_9ACTN/112-300  AC A0A4R4XKM4.1
#=GS A0A5B1MB12_9ACTN/123-291  AC A0A5B1MB12.1
#=GS A0A1E3S2T3_9MYCO/113-355  AC A0A1E3S2T3.1
#=GS A0A1H8X2V8_9PSEU/117-325  AC A0A1H8X2V8.1
#=GS A0A542DWG7_9MICO/121-343  AC A0A542DWG7.1
#=GS A0A1A1YS37_9MYCO/118-310  AC A0A1A1YS37.1
#=GS A0A6I5C5N1_9ACTN/119-336  AC A0A6I5C5N1.1
#=GS A0A1Q4YSJ1_9PSEU/118-312  AC A0A1Q4YSJ1.1
#=GS A0A0Q8E8S2_9ACTN/114-303  AC A0A0Q8E8S2.1
#=GS A0A239ICR0_9ACTN/174-380  AC A0A239ICR0.1
#=GS A0A2M9J7A3_9ACTN/120-329  AC A0A2M9J7A3.1
#=GS A0A132SWT0_9MYCO/118-335  AC A0A132SWT0.1
#=GS A0A2A2Z7G1_9ACTN/121-335  AC A0A2A2Z7G1.1
#=GS A0A365HC53_9ACTN/125-336  AC A0A365HC53.1
#=GS B2HFF0_MYCMM/116-309      AC B2HFF0.1
#=GS Q5YPI8_NOCFA/117-304      AC Q5YPI8.1
#=GS A0A1Q9U690_9NOCA/119-308  AC A0A1Q9U690.1
#=GS M3VJH5_9ACTN/114-323      AC M3VJH5.1
#=GS A0A1G7GFD7_9PSEU/122-326  AC A0A1G7GFD7.1
#=GS B5HAC2_STRE2/138-338      AC B5HAC2.1
#=GS A0A1Q4HB82_9MYCO/121-306  AC A0A1Q4HB82.1
#=GS A0A1M9JTG2_9MYCO/117-260  AC A0A1M9JTG2.1
#=GS A0A1E8Q355_9MYCO/116-327  AC A0A1E8Q355.1
#=GS A0A1A3PFM3_9MYCO/128-300  AC A0A1A3PFM3.1
#=GS A0A0T1W1E1_9MYCO/133-314  AC A0A0T1W1E1.1
#=GS A0A1Q4HIA1_9MYCO/117-326  AC A0A1Q4HIA1.1
#=GS A0A370HTL9_9NOCA/116-307  AC A0A370HTL9.1
#=GS D0LA29_GORB4/133-352      AC D0LA29.1
#=GS A0A022LNZ2_9ACTN/112-315  AC A0A022LNZ2.1
#=GS A0A1S1N0F5_9MYCO/121-323  AC A0A1S1N0F5.1
#=GS A0A542CSB5_9PSEU/117-333  AC A0A542CSB5.1
#=GS A0A3N0GUJ1_9ACTN/127-310  AC A0A3N0GUJ1.1
#=GS A0A4V5MXK2_9ACTN/133-349  AC A0A4V5MXK2.1
#=GS A0A5B1L9D0_9ACTN/115-307  AC A0A5B1L9D0.1
#=GS A0A1A3Q6Y7_9MYCO/116-327  AC A0A1A3Q6Y7.1
#=GS A0A1H3LG09_9PSEU/119-326  AC A0A1H3LG09.1
#=GS D5UQ87_TSUPD/124-346      AC D5UQ87.1
#=GS A0A1G8HZ05_9ACTN/111-297  AC A0A1G8HZ05.1
#=GS K5BGP4_MYCHD/105-315      AC K5BGP4.1
#=GS A0A3N0DX25_9ACTN/137-343  AC A0A3N0DX25.1
#=GS A0A542DR34_9PSEU/129-325  AC A0A542DR34.1
#=GS A0A0D1J780_9MYCO/121-329  AC A0A0D1J780.1
#=GS A0A101JEQ3_9ACTN/121-331  AC A0A101JEQ3.1
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