GenomeNet

Database: Pfam
Entry: NICE-1
LinkDB: NICE-1
Original site: NICE-1 
#=GF ID   NICE-1
#=GF AC   PF15845.8
#=GF DE   Cysteine-rich C-terminal 1 family
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:Q9UGL9
#=GF GA   27.00 27.00;
#=GF TC   35.00 31.50;
#=GF NC   25.50 25.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Disordered
#=GF DR   INTERPRO; IPR031698;
#=GF DR   SO; 0100003; intrinsically_unstructured_polypeptide_region;
#=GF CC   NICE-1 is family of proteins found in primates. Proteins in this
#=GF CC   family are typically between 51 and 105 amino acids in length.
#=GF SQ   45
#=GS A0A286XD84_CAVPO/8-108   AC A0A286XD84.1
#=GS A0A2U3Z2E5_LEPWE/9-100   AC A0A2U3Z2E5.1
#=GS A0A5F8A077_MACMU/9-103   AC A0A5F8A077.1
#=GS A0A2R8ZB96_PANPA/9-103   AC A0A2R8ZB96.1
#=GS A0A1U7TPC8_CARSF/9-112   AC A0A1U7TPC8.1
#=GS A0A1S3F3V2_DIPOR/5-97    AC A0A1S3F3V2.1
#=GS A0A4U1EQH8_MONMO/74-154  AC A0A4U1EQH8.1
#=GS A0A2K6EPV7_PROCO/9-101   AC A0A2K6EPV7.1
#=GS A0A6I9LF84_PERMB/5-97    AC A0A6I9LF84.1
#=GS A0A096N7J6_PAPAN/9-103   AC A0A096N7J6.1
#=GS A0A3P4S2N5_GULGU/9-51    AC A0A3P4S2N5.1
#=GS G1QBD5_MYOLU/6-52        AC G1QBD5.1
#=GS A0A5E4CTF2_MARMO/44-133  AC A0A5E4CTF2.1
#=GS A0A5J5MZH8_MUNRE/44-104  AC A0A5J5MZH8.1
#=GS A0A3Q7MZZ2_CALUR/9-88    AC A0A3Q7MZZ2.1
#=GS A0A2K6AZU0_MACNE/9-103   AC A0A2K6AZU0.1
#=GS A0A2K5KVI5_CERAT/9-103   AC A0A2K5KVI5.1
#=GS A0A484GHH6_SOUCH/6-87    AC A0A484GHH6.1
#=GS A0A2I3G7A0_NOMLE/9-96    AC A0A2I3G7A0.1
#=GS CRCT1_HUMAN/9-98         AC Q9UGL9.1
#=GS A0A6J1Y8V3_ACIJB/9-104   AC A0A6J1Y8V3.1
#=GS G1QBD5_MYOLU/45-106      AC G1QBD5.1
#=GS A0A6J2KYG6_9CHIR/9-107   AC A0A6J2KYG6.1
#=GS A0A6J3HB91_SAPAP/63-148  AC A0A6J3HB91.1
#=GS A0A2Y9S7E9_PHYMC/6-86    AC A0A2Y9S7E9.1
#=GS A0A3Q7QY42_VULVU/9-93    AC A0A3Q7QY42.1
#=GS A0A6J0XXS6_ODOVR/6-99    AC A0A6J0XXS6.1
#=GS A0A2K5H7H4_COLAP/9-103   AC A0A2K5H7H4.1
#=GS Q6PAI5_MOUSE/5-100       AC Q6PAI5.1
#=GS A0A3Q7VI30_URSAR/9-96    AC A0A3Q7VI30.1
#=GS A0A2R8MNJ9_CALJA/9-104   AC A0A2R8MNJ9.1
#=GS H2Q006_PANTR/9-103       AC H2Q006.1
#=GS J9P9R8_CANLF/9-93        AC J9P9R8.1
#=GS A0A5J5MZH8_MUNRE/6-52    AC A0A5J5MZH8.1
#=GS Q0II20_BOVIN/6-113       AC Q0II20.1
#=GS H2N5S5_PONAB/9-103       AC H2N5S5.1
#=GS A0A4W2F879_BOBOX/6-113   AC A0A4W2F879.1
#=GS A0A384CGK5_URSMA/9-66    AC A0A384CGK5.1
#=GS A0A2K5XZ11_MANLE/9-103   AC A0A2K5XZ11.1
#=GS A0A6I9JGE7_CHRAS/6-105   AC A0A6I9JGE7.1
#=GS A0A2U3ZWI1_ODORO/9-93    AC A0A2U3ZWI1.1
#=GS A0A6P6GZD8_PUMCO/9-104   AC A0A6P6GZD8.1
#=GS D3ZGI6_RAT/5-98          AC D3ZGI6.1
#=GS A0A2Y9LDR4_ENHLU/9-101   AC A0A2Y9LDR4.1
#=GS A0A2Y9H0V3_NEOSC/9-94    AC A0A2Y9H0V3.1
A0A286XD84_CAVPO/8-108              ..SGKGFSKGSSQGP.TPC..PAPA..P..ApvP....SR.S.S.S..CCggccgs....gvgnggCCG..GGC..CG.DA..GCCGS....S..SNGCCCFPRRRRRQCGGGGC.CR--RSQRSQSSCNNQSSGCCGG....................
A0A2U3Z2E5_LEPWE/9-100              ..SAKGFSKGCAQGP.APC..PAPA..P..A..A....SS.ScC.S..CC................GSD..GGC..CG.SG..GCCGSggccG..SSGCGCFPRRRRRQRRSGCCsCCGGG---SQSSSNVQSQGCCGG....................
A0A5F8A077_MACMU/9-103              ..SAKGFSKGSSQGP.APCpaPAPT..P..A..P....AS.S.S.S..CCgg...........gccGSG..GGC..CG.DS..GCCGS....S..STSCCCFPRRRRRQRSSGCC.CCGGGSQRSQRS-NNQSSGCCSG....................
A0A2R8ZB96_PANPA/9-103              ..SAKGFSKGSSQGP.APCpaPAPT..P..A..P....AS.S.S.S..CCgg...........gccGSG..RGC..CG.DS..GCCGS....S..STSCCCFPRRRRRQRSSGCC.CCGGGSQRSQRS-NNQSSGCCSG....................
A0A1U7TPC8_CARSF/9-112              ..SSKAFSKGSSQGP.TPCpaPAPA..P..A..P....SS.S.S.S..CCsggccg....sgggccGSG..GGC..CG.SS.gGCCGS....S..SSGCCCFPIRRRRQRSRGCC.CCRGGSQRSQRSSNCQSSGCCSG....................
A0A1S3F3V2_DIPOR/5-97               .c-AKGFSKGSSQGP.TPC..PAPA..P..A..P....SS.S.S.SssCCrg............ccGSS..GGC..CG.SS.gGCCGS....S..STGCCCFPRRRR-QRR-GCC.CGGG-GSSSQRSCNNQSSGCCSG....................
A0A4U1EQH8_MONMO/74-154             ..SGKDFSKGSSQDT.K-G..SCPT..P..A..P....DT.-.S.S..CC................--G..SGC..CG.DS..GCCGS....S..SVGCCCLPLRRRLLGSPCCC.CCADSSQRSRSS----SSGCCGG....................
A0A2K6EPV7_PROCO/9-101              ..AAKGFSKGSSQGP.APC..PAPT..P..A..P....SS.S.S.S..CCdg............ccGSG..GGC..CG.SS..GCCGS....S..STGCCCFPLRRRRQRGRGCC.CCGGGSQRSQSSCNAGSR-CCSGg...................
A0A6I9LF84_PERMB/5-97               ..GAKGFSKGSSQGS.APC..SAPT..P..A..P....AP.S.S.S..CCsrg..........ccgGGG..CGC..GG.DS..GCCGS....S..STGCCCFPRRRRRQRTGGCC.-CGG-SQRSQRSCNNQSSGCCGG....................
A0A096N7J6_PAPAN/9-103              ..SAKGFSKGSSQGP.APCpaPAPT..P..A..P....AS.S.S.S..CCgg...........gccGSG..GGC..CG.DS..GCCGS....S..STSCCCFPRRRRRQRSSGCC.CCGGGSQRSQRS-NNQSSGCCSG....................
A0A3P4S2N5_GULGU/9-51               .f-AKGFSKGSSQGP.TPC..PAP-..-..A..P....TA.S.S.S..CC................---..-GC..CG.SSsgGCCGS....-..--------------------.-----------------------gg..................
G1QBD5_MYOLU/6-52                   ..SAKGFSKGSSQGP.APC..PAPV..P..S..R....AS.S.S.-..CC................---..-GG..CG.DS..GCCGS....G..CCGS----------------.-----------------------gs..................
A0A5E4CTF2_MARMO/44-133             ..SAKGFSKGSSQGP.APC..PAPA..P..A..P....AP.S.S.S..GG................CCG..RGC..CGsDS..GCCGS....G..STGCCCFPRRRRRQRGGGCC.CCGGGSQRSQCSSDNRGSGCCSG....................
A0A5J5MZH8_MUNRE/44-104             .g-------------.---..----..-..-..-....--.-.-.-..CC................GSSgdSGC..CG.DC..GCGGS....S..SVGCCCFPRRRRRQGRSGCG.CCGGSNQSSRYS---SSSGCCG-c...................
A0A3Q7MZZ2_CALUR/9-88               ..SSKGFSKGCAQSP.APC..--PT..P..A..P....AA.S.S.S..CC................GC-..--C..GS.DG..GCCG-....-..SSGCGCFPRRRRRQRRSGCCsCCGGG---NQSSSNVQSQGCCGG....................
A0A2K6AZU0_MACNE/9-103              ..SAKGFSKGSSQGP.APCpaPAPT..P..A..P....AS.S.S.S..CCgg...........gccGSG..GGC..CG.DS..GCCGS....S..STSCCCFPRRRRRQRSSGCC.CCGGGSQRSQRS-NNQSSGCCSG....................
A0A2K5KVI5_CERAT/9-103              ..SAKGFSKGSSQGP.APCpaPAPT..P..A..P....AS.S.S.S..CCgg...........gccGSG..GGC..CG.DS..GCCGS....S..STSCCCFPRRRRRQRSSGCC.CCGGGSQRSQRS-NNQSSGCCSG....................
A0A484GHH6_SOUCH/6-87               .t-GKDFSKGSSQDTkGPC..PT--..P..A..P....D-.T.S.S..CC................--G..SGC..CR.DS..GCCGC....S..SVGCCCLPLRRRLLGGRCCC.CCTDSSQRSRSS----SSDCCGGc...................
A0A2I3G7A0_NOMLE/9-96               ..SAKGFSKGSSQGP.VPCpaPAPT..P..A..P....AS.S.S.S..CC................--G..GGC..CG.DS..GCCGS....S..STSCCCFPRRRRRQRSSGCC.CCGGGSQRSQRS-NNQSSGCCSG....................
CRCT1_HUMAN/9-98                    ..SAKGFSKGSSQGP.APCpaPAPT..P..A..P....AS.S.S.S..CC................GSG..RGC..CG.DS..GCCGS....S..STSCCCFPRRRRRQRSSGCC.CCGGGSQRSQRS-NNRSSGCCSG....................
A0A6J1Y8V3_ACIJB/9-104              ..SAKGFSKGSAQGP.SPC..PAPVpgP..V..P....AA.S.S.S..CC................DCG..EGC..CG.SG..GCCGSg..gCcgSGGCGCFPRRRRRQRRSGCCgCCGGGSQRSQSSSNAQRQGCCGG....................
G1QBD5_MYOLU/45-106                 ..-------------.---..----..-..-..-....--.-.S.G..CCg..............sGSG..SGC..CG.DS..GCCGS....V..STGCCCFPRRRRRQGRSRCG.CCGGGSQRSQCSPNTQSPGC---....................
A0A6J2KYG6_9CHIR/9-107              ..SAKGFSKGSSQGP.APC..PAPA..PsvT..P....AA.S.S.S..CCggc..........gdnGCC..GGCggCG.DC..GCCGT....T..STGCCCFPRRRRRQRRSGCG.CCGGGSRRSQCSSNTQSAGCCG-s...................
A0A6J3HB91_SAPAP/63-148             ..SAKGFSKGSSQGQ.APC..PAPA..P..A..P....AP.S.S.S..CC................---..RGC..CGsDG..GCCGS....S..STGCCCFPRRRRRQRSRGCC.CCGGGSQRSQRS-DNQGCGCCS-c...................
A0A2Y9S7E9_PHYMC/6-86               rg--KDFSKGSSQDT.N-T..SCPT..P..A..P....DA.S.-.S..CC................--G..LGC..CR.DS..CCCGS....S..SVGCCCLPVRRRLQGSCCCS.CCADSSLRSQSS----SSGCCGG....................
A0A3Q7QY42_VULVU/9-93               ..SAKGFSKGSSQGP.APC..PAPE..P..E..P....AA.S.S.S..CC................---..-GC..CG.DS..SGCG-....C..CSGCGCFPRRRRRQRRSGCCsCCGGRSQRSQSSSNVQSQGCCSG....................
A0A6J0XXS6_ODOVR/6-99               ..SAKGSPKGSSQGP.TPC..PAPA..P..D..T....SS.S.S.S.gCCgng.........ccgsSGD..SGC..CG.DC..GCGGS....S..SVGCCCFPRRRRRQGRRGCG.CCGG---SNQSSGYYGSSGCCG-c...................
A0A2K5H7H4_COLAP/9-103              ..SAKGFSKGSSQGP.APCpaPAPT..P..A..P....AS.S.S.S..CCgg...........gccGSG..GGC..CG.DS..DCCGS....S..STSCCCFPRRRRRQRSSGCC.CCGGGSQRSQRS-NNQSSGCCSG....................
Q6PAI5_MOUSE/5-100                  ..GAKGFSKGSSQSS.APC..PAPT..P..A..P....AS.S.SsS..CCggg..........ccrGCG..GGC..GG.DS..GCCGS....S..STGCCCFPRRRRRQRSGGCG.CCCGGSQRSQRSCNNQSSGCCSG....................
A0A3Q7VI30_URSAR/9-96               ..SAKGFSKGSAQGP.APC..PSSA..P..A..P....AP.S.S.S..CCg.............ccGSG..GGC..CG.SG..GCCS-....-..SSGCGCFPRRRRRQRRSGCCsCCGA---GSQSSSDIQSQGCCGG....................
A0A2R8MNJ9_CALJA/9-104              ..SAKGFSKGSSQGP.APCpaPAPT..P..A..P....AS.S.S.S..CCgg...........gccGSD..GGC..CGsDG..GCCGS....S..STSCCCFPRRRRRQRSRGCC.CCGGGSQRSQRS-NNQGSGCCSG....................
H2Q006_PANTR/9-103                  ..SAKGFSKGSSQGP.APCpaPAPT..P..A..P....AS.S.S.S..CCgg...........gccGSG..RGC..CG.DS..GCCGS....S..STSCCCFPRRRRRQRSSGCC.CCGGGSQRSQRS-NNQSSGCCSG....................
J9P9R8_CANLF/9-93                   ..SAKGFSKGSSQGP.APC..PAPE..P..E..P....AA.S.A.S..CC................---..-GC..CG.DS..SGCG-....C..CSGCGCFPRRRRRQRRSGCCsCCGGRSQRSQSSSNVQSQGCCGG....................
A0A5J5MZH8_MUNRE/6-52               ..SAKGSPKGSSQGP.TPC..PAPA..P..D..T....SS.C.S.S..GC................-CG..NGC..CG.N-..GCCGS....S..G-------------------.-----------------------ds..................
Q0II20_BOVIN/6-113                  ..SAKGSPRGSSQGP.TPC..PAPC..P..A..PepdtSScS.S.G..CCgngccgngccgssgdsGCC..GDC.gCG.DC..GCGGS....S..SVGCCCFPRRRRRQGRRGCG.CCGGSSQRSQYS---SSSGCCG-c...................
H2N5S5_PONAB/9-103                  ..SAKGFSKGSSQGP.APCpaPAPT..P..A..P....AS.S.S.S..CCgg...........gccGSG..GGC..CG.DS..GCCGS....S..STSCCCFPRRRRRQRSSGCC.CCGGGSQRSQRS-NNQSSGCCSG....................
A0A4W2F879_BOBOX/6-113              ..SAKGSPRGSSQGP.TPC..PAPC..P..A..PepdtSScS.S.G..CCgngccgngccgssgdsGCC..GDC.gCG.DC..GCGGS....S..SVGCCCFPRRRRRQGRRGCG.CCGGSSQRSQYS---SSSGCCG-c...................
A0A384CGK5_URSMA/9-66               ..SAKGFSKGSAQGP.APC..PSSA..P..A..P....AP.S.S.S..CC................GCR..GPG..GS.--..-----....-..--------------------.-----------------------lpfgcdvlptepeavpappr
A0A2K5XZ11_MANLE/9-103              ..SAKGFSKGSSQGP.APCpaPAPT..P..A..P....AS.S.S.S..CCgg...........gccGSG..GGC..CG.DS..GCCGS....S..STSCCCFPRRRRRQRSSGCC.CCGGGSQRSQRS-NNQSSGCCSG....................
A0A6I9JGE7_CHRAS/6-105              ..SAKGFSKGSSQGSsVPC..PAPT..P..A..P....AS.S.S.S..CCrgcc.......sssggGCG.sGGC..CGsNG..GCCGS....S..STGCCCFPRRRRRQRR-GCS.CCGGGSQRSQCSTNNQSSGCCSG....................
A0A2U3ZWI1_ODORO/9-93               ..SSKGFSKGCAQSP.APC..PAPA..P..A..A....SS.S.CcG..CC................GSD..GGC..CG.SS..-GCG-....-..SSGCGCFPRRRRRQRRSGCCsCCGGGSQ---RSSNVQSQGCCGG....................
A0A6P6GZD8_PUMCO/9-104              ..SAKGFSKGSAQGP.SPC..PAPVpgP..V..P....AA.S.S.S..CC................DCG..EGC..CG.SG..GCCGSg..gCcgSGGCGCFPRRRRRQRRSGCCgCCGGGSQRSQSSSNAQRQGCCGG....................
D3ZGI6_RAT/5-98                     ..GAKGFSKGSSQSS.APC..SAPT..P..A..P....TS.S.S.S..CCdgg..........ccrGCG..GGC..GG.DS..GCCGS....S..STGCCCFPRRRRRQRTGGCC.CCGG-SQRSQRSCNNQSSGCCSG....................
A0A2Y9LDR4_ENHLU/9-101              ..SAKGFSKGSSQGP.APC..PAP-..-..A..P....TA.S.S.S..CCgc............cgSSG..GGC..CG.SG..GCCGSggccG..SSGCGCFPRRRRRQPRSGCCsCCGGG---SQSSSNVQSQGCCGG....................
A0A2Y9H0V3_NEOSC/9-94               ..SAKGFSKGCAQGP.APC..PAPA..P..A..A....SS.ScC.S..CC................GLD..GGC..CG.SG..GCCG-....-..SSGCGCFPRRRRRQRRSGCCsCCGGG---SQSSSNVQSQGCCGG....................
#=GC seq_cons                       ..SAKGFSKGSSQGP.APC..PAPs..P..A..P....uo.S.S.S..CC................GsG..uGC..CG.DS..GCCGS....S..SoGCCCFPRRRRRQRpuGCC.CCGGGSQRSQpS.NsQSSGCCuG....................
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