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Database: Pfam
Entry: Nod1
LinkDB: Nod1
Original site: Nod1 
#=GF ID   Nod1
#=GF AC   PF17114.8
#=GF DE   Gef2-related medial cortical node protein Nod1
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Phmmer:Q10443
#=GF GA   28.20 28.20;
#=GF TC   28.20 28.50;
#=GF NC   28.00 27.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   23966468
#=GF RT   Cooperation between Rho-GEF Gef2 and its binding partner Nod1 in
#=GF RT   the regulation of fission yeast cytokinesis.
#=GF RA   Zhu YH, Ye Y, Wu Z, Wu JQ;
#=GF RL   Mol Biol Cell. 2013;24:3187-3204.
#=GF DR   INTERPRO; IPR032634;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a small family of fungal proteins that are involved in
#=GF CC   cytokinesis, the last stage of the cell-division cycle. Nod1
#=GF CC   co-localises with Gef2 - RhoGEF - in the contractile ring and
#=GF CC   its precursor cortical nodes. Nod1 and Gef2 interact through
#=GF CC   this C-terminal region of each, this interaction being important
#=GF CC   for their localisation [1].
#=GF SQ   25
#=GS B6JZ65_SCHJY/39-185        AC B6JZ65.1
#=GS A0A420H9J5_9PEZI/898-1038  AC A0A420H9J5.1
#=GS A0A517LBW8_9PEZI/909-1047  AC A0A517LBW8.1
#=GS R7YG42_CONA1/903-1043      AC R7YG42.1
#=GS Q0U2F2_PHANO/817-957       AC Q0U2F2.2
#=GS S9X7C9_SCHCR/824-967       AC S9X7C9.1
#=GS A0A1J9RQM0_9PEZI/913-1052  AC A0A1J9RQM0.1
#=GS A0A420I5K1_9PEZI/896-1036  AC A0A420I5K1.1
#=GS A0A178B5V5_9PLEO/759-899   AC A0A178B5V5.1
#=GS A0A164ZPY1_XYLHT/918-1057  AC A0A164ZPY1.1
#=GS L0PDK9_PNEJ8/824-965       AC L0PDK9.1
#=GS A0A4Z1PB02_9PEZI/909-1047  AC A0A4Z1PB02.1
#=GS A0A2S4Q299_9PEZI/848-988   AC A0A2S4Q299.1
#=GS A0A7C8MAN8_9PLEO/901-1040  AC A0A7C8MAN8.1
#=GS B6JWM9_SCHJY/819-962       AC B6JWM9.1
#=GS A0A1Y1YWF3_9PLEO/903-1042  AC A0A1Y1YWF3.1
#=GS S9VWV7_SCHCR/61-205        AC S9VWV7.1
#=GS A0A0B1PC60_UNCNE/896-1036  AC A0A0B1PC60.1
#=GS A0A1S8BE57_9PEZI/911-1050  AC A0A1S8BE57.1
#=GS A0A178EEH2_9PLEO/899-1039  AC A0A178EEH2.1
#=GS YDEA_SCHPO/59-203          AC Q10443.1
#=GS M7NPP7_PNEMU/871-1011      AC M7NPP7.1
#=GS A0A0W4ZQ76_PNEJ7/638-779   AC A0A0W4ZQ76.1
#=GS GEF2_SCHPO/824-967         AC Q09733.1
#=GS K2S609_MACPH/903-1042      AC K2S609.1
B6JZ65_SCHJY/39-185                   ..MMAVSEEVDKSSENvKALLQNLPVKILFGSFLFFVKDKAHAHAGHVLSEKLCNEF...LS.LPLDLNNKSLFSRNVEIIQ.TLTEELPPGVFSLLQAFFTTVQEVYQKLD-GDYQENIqfFASISAVVCPRKCVHKMYPIVEFISIATPYLWK...........
A0A420H9J5_9PEZI/898-1038             .v-NAIYNTFIENPYD.QRAASEVTIDILFAAFEKYLRMAWKEQMGDVISLQTLDEL...QL.QALRLAS----GDFSHYVR.LILSEMTPQNRRAFISIVKLLADLLDGCGNDGDRGTI..TAAFAELLVIDGNPHDYINLLDRLILDQEKIFQ...........
A0A517LBW8_9PEZI/909-1047             .v-NELYNALLEDPTN.FEIMGQSPVDVLFAAFEKFIKIAWFDKIGPIISPATWSAI..qSK.LDSVHPG--DFE---EFFR.NCFGDMSPQNQRALKACVKLLEDLLGGTNNDGDRGIM..TASFAEVLGPEGHTNEFVSVL------------drlvedvqal.
R7YG42_CONA1/903-1043                 .v-NELYNSLLENPIN.HEVAAHAPVDVLFASFEKFLKVAWKEKMGAVISHNTLAVI...QS.KSDSFYP---GEFE-EYFRlTIGESLPQ-NQRALQAIIKLLADLLAGTG-NDSDRGI.lTAAFAEVLVPEGNAHDYISLLDRLVEDVDALF-a..........
Q0U2F2_PHANO/817-957                  .v-NELYNSILENPSN.LDLAAQSSVDVLFAVFEKFLNIAWKERMGPVLSHATLVSL...QM.RSDSMYP-GEFEDF---FR.TTVNEFSPQNQRALRAVIQLLAELLDGTSNDGDRGIL..TAAFAEMIVPAGNANDFISLMDRLVQDIEALF-a..........
S9X7C9_SCHCR/824-967                  .l-DILLEDILKESPE.FKRIQKLPEAQIYLLFWKYLKLFVVRKYGSLLPSMFIQRL...SN.NGYIGFSYDLKVSL-QQIQ.SCLQELPQQNLRILDVVLNIVSELLLRLPLRDQCETL..IEQMASVLSPPLYRNSAIEVIRFMTYYYDQLFK...........
A0A1J9RQM0_9PEZI/913-1052             .v-NELYNSLLEEPAN.VELASQQPVDVLFRSYEKFLQTAWKEKLGLVVPVEILNAL...QS.HPEDYPG--DFEEF---FR.KQIGELMPQNQRALRASIKLLADLLAGTANDGDRGMI..TAAFAEVLVPDGNSHDFISLLD-----------rfiedidtlfg
A0A420I5K1_9PEZI/896-1036             .v-NAVYNTFIENPED.QRIASEATIDILFAAFKKYLRIAWMEQMGDVVPQQTLDEL...QL.QALRLVS----GDFAQYVR.LILSEMTPQNRRAFISIIKLLADLLDGCFNDGDQGEI..TAAFAQLLAVEGNSHDYINLLDRLVMDHEMIFQ...........
A0A178B5V5_9PLEO/759-899              .v-NELYNSILENPSN.LDLAAQSSVDVLFAVFEKFLNIAWKERMGPVLSHATLVSL...QM.RSDSMYP-GEFEDF---FR.TTLSEFSTQNQRALRAIIQLLAELLEGTSNDGDRGTL..TAAFAEMIVPAGNANDFISLMDRLVQDIEALF-p..........
A0A164ZPY1_XYLHT/918-1057             .v-NEIYNSLLEDPTR.HQQAAEVSVDVLFSAFEKFLTVAWKERFGAVMERSTWSSL...QD.KSETLLP---KDFA-AYFK.EKLSELAPQNQRAFKLIIRLFADLLDGAGNDGDCGAL..TATFAEVLVPDGNAYEYITLL------------drlgedveily
L0PDK9_PNEJ8/824-965                  si--DLSNEIAKNPQK.DYAVLGSPLKIGYAAFKHYIKTHVSKKIGPVLPYEYIKSC...LN.IIEGFDS---IDEKIHKIH.NISLDLPYESHAVLCLVIYLTLHVLNKAY-KEKCLKI.lLLMISECLVSVYDVPAFIPVLKLMARNFSQIF-y..........
A0A4Z1PB02_9PEZI/909-1047             .v-NELYNALLENPSD.VEIMGQSPVDVLFAAFEKFIKIAWFDKIGPIISLATWNAI...QSkLDSVQPG--DFE---EFFR.HCFGEMSPQNQRALKACVKLLEDLLSGTSNDGDRGIM..TASFAEVLGPEGHTHEFVSVL------------drlvedvqal.
A0A2S4Q299_9PEZI/848-988              .v-NAVYNTFIENPDD.HRIASEVTIDILFAAFKKYLRIAWMEQMGDVVPQQTLDEL...QL.QALRLGS----GDFAQYVR.LILSEMTPQNRRAFISIVKLLADLLDGCCNDGDQGEI..TAAFAELLAVEGNSHDYINLLDRLVMDQGMIFQ...........
A0A7C8MAN8_9PLEO/901-1040             .v-NELYNALLENSSN.LELASQSPVDVLFATLEKFLNIAWREKMGPIISHTTLVSL...QT.KSDSMYP---GEFE-ESFR.TTFNEMSPQNQRSLRAIIKLLAELLDGTANDGDRGVL..TAAFAEMLVPEGSANDFISLVD-----------rfiqdidvlf.
B6JWM9_SCHJY/819-962                  .v-RKIYDAVTKTPKR.EYVVMGSRPKLIFAAFKNYLSNYLLKKAGYLLPAILFQRLsvvEN.LDLSLNS----EKAIQLVR.DLLHELTETSNALLEIVMSITSELLLRLPRKDQCDHV..LEAVAAAISPSMFGYTARQLVQFIAYNSEELFG...........
A0A1Y1YWF3_9PLEO/903-1042             .v-NEVYNSLLENPAN.LDVAAQSSVDVLFAAFEKFLKIAWKEKMGPVISQATLVSL...QM.KSDSMYP---GEFE-EFFR.TTFNEIAPQNQRSLRAIIKLLAELLDGTGNDGDRGIL..TAAFAEMIVPEGNPNDFISLID-----------rfiqdidalf.
S9VWV7_SCHCR/61-205                   ..MIKLSFLIADSPYR.PISLESVPSKILFGSFLFYVKDKIYEKAGHILDRPFCFAL...RK.LVSDNSN-LNHEFFLQQVK.SNFLSLPKIKIKMLSVFFSIVQIVLSKLR-GGSHERVqfFASIAAVILPKEQINDMYQLVEYISLNAQKIFQ...........
A0A0B1PC60_UNCNE/896-1036             .v-NAVYNTFIENPYD.QRIASEVTIDILFLAFKKYLRIAWMEQMGDVVSQQTLDEL...QL.QALRLIS----GDFAHYVR.LILSEMTPQNRRAFISIVKLLSDMLDGCSSDGDQGEI..TAAFAELLVIDGNPHDYINLLDRLVMDQENIFQ...........
A0A1S8BE57_9PEZI/911-1050             .v-NELYNSLLEEPTN.VELASQQPVDVLFRSFEKFLQTAWREKLGLVVPMDVLSAL...QS.HPEDYPG--DFEEF---FR.KQISDLMPQNQRALRASIKLLADLLEGTGNDGDRGMI..TAAFAEVLVPDGNSHDFISLLD-----------rfiedidtlfg
A0A178EEH2_9PLEO/899-1039             .v-NELYNSLLENPAN.LDLAGQSSVDVLFAVFDKFLSVAWKERMGPVLSHATLVSL...QM.RSDSMYP---GEFE-EFFR.TTVVDLTPQNQRALRAVIRLLAELLDGTSNDGDRGIL..TAAFAEILLPAGNANDFISLMDRLVQDIDALF-p..........
YDEA_SCHPO/59-203                     ..MVCLSTSIAENPYQ.SLSLESVPSKILFGSFLFYVKDRIPEKAGYIIEEQFCKRL...QQ.IDYDAYSFSPKECN-EKLK.NIFSEFSQMKLKMLSVFFSIVQILLPKLS-GDYQEHVqfFASISAVVAPRGYVFEIYHAVEHLSLEAREVFQ...........
M7NPP7_PNEMU/871-1011                 .a-IELSNEIAKNPEK.NYAILGSPLKIGYAAFKHYMKTHVNKKIGPILPQEFIKSC...LN.IIGEPDS---IDEKISKIH.DITLVLPQGNYVILYLVIYLTLHILNKTH-GEVLKVL..LSIVSEGIVPKNDVSVLIPILKFMTQNFSQVF-y..........
A0A0W4ZQ76_PNEJ7/638-779              si--DLSNEIAKNPQK.DYAVLGSPLKIGYAAFKHYIKTHVSKKIGPVLPYEYIKSC...LN.IIEGFDS---IDEKIHKIH.NISLDLPYESHAVLCLVIYLTLHVLNKAY-KEKCLKI.lLLMISECLVSVYDVPAFIPVLKLMARNFSQIF-y..........
GEF2_SCHPO/824-967                    .g-DELYDNILKETFN.EELLSHYPPNIIYATFQKYLSSFINRKFGVLLSSSFIQQLntvEN.LNLSFNS----TDAVYHLK.KILQDLPESSLKILENIFSIASDLLLRLPLKDQCDFV..TKQLAIALAPSMFGSNAVELVYYLAYHSDRIFG...........
K2S609_MACPH/903-1042                 .v-NELYNALLEEPTN.VELASQQPVDVLFRSYEKFLQVAWREKLGLVVPTDVLSAL...QS.HPESYPG--DFEEF---FR.KIIGDLQPQNQRALRASIKLLADLLEGTGNDGDRGMI..TAAFAEVLVPDGNSHDFISLLD-----------rfiedidtlfg
#=GC seq_cons                         .V.N-LYNsllENPps.hclsupsPlDlLFAuFcKaL+hAWpEKhGsVlsppslsuL...Qp.pspshsu...h-ch.phhR.shhsElsPQNpRuLpullpLLu-LLsGsssDGDpGhl..TAuFAElLlPcGssp-aIsLl-hhs.p.p.lF............
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