GenomeNet

Database: Pfam
Entry: Ntox37
LinkDB: Ntox37
Original site: Ntox37 
#=GF ID   Ntox37
#=GF AC   PF15535.8
#=GF DE   Bacterial toxin 37
#=GF PI   Toxin_57; Toxin_37;
#=GF AU   Zhang D;0000-0001-8535-7620
#=GF AU   de Souza RF;0000-0002-5284-4630
#=GF AU   Anantharaman V;0000-0001-8395-0009
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   [1]
#=GF GA   27.80 27.80;
#=GF TC   28.00 31.40;
#=GF NC   27.70 26.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF DR   INTERPRO; IPR029108;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A predicted RNase toxin found in bacterial polymorphic toxin
#=GF CC   systems.  The toxin possesses an all-beta fold and a conserved
#=GF CC   glutamate residue, and [KR] and Hx[DH] motifs. In bacterial
#=GF CC   polymorphic toxin systems, the toxin is exported by the type 2
#=GF CC   or type 7 secretion systems [1].
#=GF SQ   22
#=GS A0A125P1N9_9BURK/231-318  AC A0A125P1N9.1
#=GS A0A328YQC2_9BURK/299-385  AC A0A328YQC2.1
#=GS R5KJQ6_9CLOT/217-279      AC R5KJQ6.1
#=GS Q5YN02_NOCFA/330-413      AC Q5YN02.1
#=GS A0A323V2A5_9RHOO/93-176   AC A0A323V2A5.1
#=GS A0A323URH7_9RHOO/174-242  AC A0A323URH7.1
#=GS A0A1N2FF53_9MYCO/335-427  AC A0A1N2FF53.1
#=GS A0A1B1YRK4_9GAMM/614-677  AC A0A1B1YRK4.1
#=GS S8AQW5_DACHA/80-156       AC S8AQW5.1
#=GS D6YV35_WADCW/221-293      AC D6YV35.1
#=GS F8L2C9_PARAV/1655-1717    AC F8L2C9.1
#=GS A0A0T6UVH5_9PSED/851-912  AC A0A0T6UVH5.1
#=GS R5XUP5_9FIRM/260-323      AC R5XUP5.1
#=GS A5UT36_ROSS1/201-262      AC A5UT36.1
#=GS A0A1W2C5T1_9FIRM/520-581  AC A0A1W2C5T1.1
#=GS A0A2Z6GEA8_9PROT/268-351  AC A0A2Z6GEA8.1
#=GS A0A507ZMH7_9GAMM/686-767  AC A0A507ZMH7.1
#=GS A0A0H5DQB4_9BACT/152-221  AC A0A0H5DQB4.1
#=GS Q7NYN4_CHRVO/191-279      AC Q7NYN4.1
#=GS A0A0Q6MAP2_9BURK/245-332  AC A0A0Q6MAP2.1
#=GS A0A2H5WYS4_9BACT/171-243  AC A0A2H5WYS4.1
#=GS G1XD12_ARTOA/64-146       AC G1XD12.1
A0A125P1N9_9BURK/231-318             .............AKPPEN........AYDP.IGpKAPG....kPGAVEGFNDPKGG-EDW...VRNPNP.GR.Ggsshgwqddr......grvwcptgqggRahGGPHWDVELPNG..RQVNVPPG-q......
A0A328YQC2_9BURK/299-385             ............i-KPPAN........AYDP.NG.PKAPg...kPSEADGFKSPKGG-DNW...VPNPNP.GK.Ggsswgwqdakg....dvwcptgqggnaH..GGPHWDVQTPGG..DYRNVKP--r......
R5KJQ6_9CLOT/217-279                 .............NKAPGK........DFEW.RG.N-PD....iKKNIGNWFNKKTGESFHw.dMDHPDP.--.-...........................-..IGPHWDYFRRDI.dNEYRIFPD-n......
Q5YN02_NOCFA/330-413                 ............y-KPPAN........AYDP.NG.PKAPg...rPGDAEGFVPPKGG-DRW...VPNPN-.GRgFgwedadgnv........wvptgqggaaH..GGPHWDVEFPKG..GYKNVRPGG.......
A0A323V2A5_9RHOO/93-176              .............NKPPEN........AYDP.NG.PKAPg...kPGADEGFVDPKGG-DNW...VPNPN-.GKgWgwedskgdv........wcptgqggsaH..GGPHWDVQTPGG..GYRNVRPK-r......
A0A323URH7_9RHOO/174-242             .....skppkgsd----GK........DWEW.RG.KPPQ.....GGEKGGYVNPTNPDQSVhpdLNHPAP.--.-...........................-..VGPHWDFTDRGRtpPGWRVFPDG.......
A0A1N2FF53_9MYCO/335-427             ............y-KPPGD........AFDKtGA.KAPG....qPGTAEGFVPPKAG-DRW...VPNPSArG-.KnrfgwedadgnvwvptgpgsparpgdaH..GGPHWDVIDKNG.kKIKDAYPGG.......
A0A1B1YRK4_9GAMM/614-677             ...........pk-QCPPE........-YEW.RG.KSGAq...pGSKEGNYYNPTTKEILRp.dLSHEPP.--.-...........................-..IGPHWDYRDATG..KWYRLFPDG.......
S8AQW5_DACHA/80-156                  ........kktddAKAPGKpt...eadGYVA.SK.RGDRlvreeDGKRKGWED-KKG-DLW...IPTG-P.GRlA...........................H..GGPHWDVQKKRG..GYTNVYPN-r......
D6YV35_WADCW/221-293                 .............NKTAEElhqmfvdkGYDY.GA.RSPEl...lIRGKGNYINPKNGRQFH...IDPKNS.GR.Y...........................R..EPNHVDVSRPEK..-YNGSLPKK.......
F8L2C9_PARAV/1655-1717               .............TKCPGE........EYTW.KG.DGPP.....GSGEGAWYNGKTKESLYp.dLNHPLP.--.-...........................-..KGPHWDYRDRKT.eYEERLFLDG.......
A0A0T6UVH5_9PSED/851-912             .............TQPPGE........GWEW.RG.KGTP.....GSREGAWYNPSSGESLHd.dRTHPP-.--.-...........................G..KDPHVTYTDPTG..KRWDNYGNG.......
R5XUP5_9FIRM/260-323                 .............NKAPGK........NYEW.RG.GSID.....-ENKGGWYNPKTKETLHw.dMRHPEP.--.-...........................-..HGPHWDYINKNG..GWENG----yrifpng
A5UT36_ROSS1/201-262                 .............AQPPAP........GWMW.RG.KDPP.....GGIKGAWYNPSTKESLHp.dLQHPPP.--.-...........................-..IGPHWDYKDASG..TRWRVFPNG.......
A0A1W2C5T1_9FIRM/520-581             ............v-KVPAE........GYEW.RG.NGVP.....GSKYGNWYNPNTKEWLRp.dLNHPEP.--.-...........................-..IAPHWDYGASNG..KTYRIFPDG.......
A0A2Z6GEA8_9PROT/268-351             ............m-KPPKD........AYDPnGA.KAPG....qPGDGDGFCEPKKG-PKW...GRSPN-.GRgNgwvdndgnv........wvptglggeaH..GGPHWDVQRPGG..GYDNVYPGG.......
A0A507ZMH7_9GAMM/686-767             .....gqmnessd------........----.GA.QAPG....mPGTDDGYECPKNWDGKK...VKSPN-.GRgYgwpdkkgn..........vwvptgpgsGahGGPHWDVQRPGG..GYINVYPGG.......
A0A0H5DQB4_9BACT/152-221             nksakeldamfrk------........----.KG.FDPEgp.daLNGLGNYINRKNGRQYH...I-DPKHvGR.Y...........................A..EPNHVDVGRAKA..-YSG-----nlgkk..
Q7NYN4_CHRVO/191-279                 .nkppkdatdpng------........----.-A.KAPG....kPGRTEGFCEPKKGAPTW...GRAPN-.GRgSgwidadgnvwv....ptgpssgstgdaH..GGPHWDVQKPGG..GYDNVYPGG.......
A0A0Q6MAP2_9BURK/245-332             ............v-KPPEN........AYDS.DG.--PKap.gkPGEAEGFKDPKGG-ENW...VRNPN-.GRgYgwqaadggvwc....ptgpdsgstgdaH..GGPHWDVEYPGG..RYHNIYPGG.......
A0A2H5WYS4_9BACT/171-243             ppeigdwywkpqn--PPAP........GWVW.RG.RGEP.....GSSQGSWHNPDTGESLHp.dLGHGTP.--.-...........................-..DGPHWDYIDPQG..RKYRYYPDG.......
G1XD12_ARTOA/64-146                  .........enepAKAPGK........----.--.----.....PKKEDGFEPPKGKSDSG...MKAPSS.GG.Kkgwpdkkgniw....kpsgptngdgsrGphGGPHWDVEDPDG..NHWNVYPGG.......
#=GC seq_cons                        ..............KsPsp........sa-..pG.psss.....suptsuahsPKsGtsha...lppPss................................t..tGPHWDhpcssG..thhslaPsG.......
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