GenomeNet

Database: Pfam
Entry: PBP1_TM
LinkDB: PBP1_TM
Original site: PBP1_TM 
#=GF ID   PBP1_TM
#=GF AC   PF14812.9
#=GF DE   Transmembrane domain of transglycosylase PBP1 at N-terminal
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   CATH:3fwl_A_01, Pfam-B_367 (release 26.0)
#=GF GA   27.80 27.80;
#=GF TC   27.80 27.80;
#=GF NC   27.70 27.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   19458048
#=GF RT   Crystal structure of the membrane-bound bifunctional
#=GF RT   transglycosylase PBP1b from  Escherichia coli.
#=GF RA   Sung MT, Lai YT, Huang CY, Chou LY, Shih HW, Cheng WC, Wong CH,
#=GF RA   Ma C;
#=GF RL   Proc Natl Acad Sci U S A. 2009;106:8824-8829.
#=GF DR   INTERPRO; IPR032730;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is the N-terminal, transmembrane, domain of the
#=GF CC   transglycosylases ()penicillin-binding proteins), the
#=GF CC   multi-domain membrane proteins essential for cell wall synthesis
#=GF CC   that are targeted by penicillin antibiotics. The TM domain is a
#=GF CC   single helix, several of whose residues lie in close proximity
#=GF CC   to hydrophobic residues in the TGT domain. The TM helix seems to
#=GF CC   be necessary for stabilizing the protein-membrane interaction,
#=GF CC   and the resulting orientation limits the interaction between
#=GF CC   PBPb1 and lipid II in the membrane in a 2D lateral diffusion
#=GF CC   fashion [1].
#=GF SQ   128
#=GS A0A1H8XUY3_9PSEU/107-169  AC A0A1H8XUY3.1
#=GS A0A089Q2B0_9ENTR/1-83     AC A0A089Q2B0.1
#=GS Q8ZRQ3_SALTY/1-74         AC Q8ZRQ3.1
#=GS A0A2X4TLC6_SALER/1-52     AC A0A2X4TLC6.1
#=GS A0A4S2DRU8_9CLOT/292-360  AC A0A4S2DRU8.1
#=GS C5BH79_EDWI9/1-87         AC C5BH79.1
#=GS B2VCM2_ERWT9/4-82         AC B2VCM2.1
#=GS A8ALE0_CITK8/1-78         AC A8ALE0.1
#=GS A0A378C0Q6_KLEPO/1-32     AC A0A378C0Q6.1
#=GS A0A0H3GIH5_KLEPH/1-79     AC A0A0H3GIH5.1
#=GS A0A151UKV6_9GAMM/1-64     AC A0A151UKV6.1
#=GS A0A1B7JMM2_9GAMM/1-93     AC A0A1B7JMM2.1
#=GS A0A3L7LR98_9GAMM/1-82     AC A0A3L7LR98.1
#=GS A6T4V3_KLEP7/1-79         AC A6T4V3.1
#=GS H2IQ93_RAHAC/1-95         AC H2IQ93.1
#=GS A0A3R8Z2R4_9GAMM/1-76     AC A0A3R8Z2R4.1
#=GS J2XC22_KLEPN/1-79         AC J2XC22.1
#=GS A0A6M8U5G6_9GAMM/1-81     AC A0A6M8U5G6.1
#=GS D8MNB6_ERWBE/1-80         AC D8MNB6.1
#=GS A0A2T0BJT0_9CLOT/294-359  AC A0A2T0BJT0.1
#=GS A0A0Q4MV86_9GAMM/1-78     AC A0A0Q4MV86.1
#=GS A0A2I8Q8F4_9ENTR/1-78     AC A0A2I8Q8F4.1
#=GS A0A2I5T5M1_SERS3/1-86     AC A0A2I5T5M1.1
#=GS A0A4R1NHN5_9GAMM/1-79     AC A0A4R1NHN5.1
#=GS A0A0B7GFW7_KLEVA/1-79     AC A0A0B7GFW7.1
#=GS D2U404_9GAMM/1-81         AC D2U404.1
#=GS A0A4R6ELG8_9ENTR/1-77     AC A0A4R6ELG8.1
#=GS A0A090UZ74_PSEVU/1-79     AC A0A090UZ74.1
#=GS A0A6B2FQE1_9ENTR/1-78     AC A0A6B2FQE1.1
#=GS A0A0J5LVU0_PLUGE/1-79     AC A0A0J5LVU0.1
#=GS A0A0L7SZB5_9GAMM/1-82     AC A0A0L7SZB5.1
#=GS A0A6L2ZMW4_9ENTR/1-71     AC A0A6L2ZMW4.1
#=GS A0A6L6IE98_9ESCH/1-78     AC A0A6L6IE98.1
#=GS A0A085GJ62_9ENTR/10-90    AC A0A085GJ62.1
#=GS A0A2Y9CKA9_9GAMM/1-82     AC A0A2Y9CKA9.1
#=GS A0A0J8YWE8_9GAMM/1-78     AC A0A0J8YWE8.1
#=GS A0A0J8VNI1_9ENTR/1-81     AC A0A0J8VNI1.1
#=GS W0HML6_9GAMM/1-74         AC W0HML6.1
#=GS Q8X903_ECO57/1-79         AC Q8X903.1
#=GS E3G929_ENTLS/1-78         AC E3G929.1
#=GS D4E1W8_SEROD/1-86         AC D4E1W8.1
#=GS A0A1X0WKI7_9GAMM/1-99     AC A0A1X0WKI7.1
#=GS A0A6L6HCS0_9GAMM/1-78     AC A0A6L6HCS0.1
#=GS E0SBK6_DICD3/1-81         AC E0SBK6.1
#=GS L0MAA6_ENTBF/1-79         AC L0MAA6.1
#=GS A0A249WEU6_9ENTR/1-80     AC A0A249WEU6.1
#=GS T0QJE5_PHOTE/1-83         AC T0QJE5.1
#=GS A0A381H8Y6_CITKO/1-37     AC A0A381H8Y6.1
#=GS A0A2N5EKD4_9GAMM/1-88     AC A0A2N5EKD4.1
#=GS A0A5J5FRE0_9GAMM/1-82     AC A0A5J5FRE0.1
#=GS A0A2V1HAJ6_9GAMM/1-93     AC A0A2V1HAJ6.1
#=GS A0A421DMJ5_9GAMM/1-87     AC A0A421DMJ5.1
#=GS A0A0G4JX91_9GAMM/1-82     AC A0A0G4JX91.1
#=GS A0A1H4EB36_9GAMM/1-76     AC A0A1H4EB36.1
#=GS A0A240CCL5_SERFI/1-82     AC A0A240CCL5.1
#=GS U3TMS9_9ENTR/1-80         AC U3TMS9.1
#=GS A0A5R9LF42_9ENTR/1-80     AC A0A5R9LF42.1
#=GS A0A2S6VPU4_9GAMM/1-82     AC A0A2S6VPU4.1
#=GS W1DUE4_KLEPN/1-79         AC W1DUE4.1
#=GS E9CN74_9GAMM/1-75         AC E9CN74.1
#=GS A0A068YVW8_9GAMM/1-75     AC A0A068YVW8.1
#=GS A0A2G8E8T3_9GAMM/1-76     AC A0A2G8E8T3.1
#=GS I2BCM2_SHIBC/1-89         AC I2BCM2.1
#=GS W1I1F0_KLEPN/1-79         AC W1I1F0.1
#=GS W1J9U1_9GAMM/1-82         AC W1J9U1.1
#=GS W0I1G7_9GAMM/1-83         AC W0I1G7.1
#=GS A0A653BEQ3_CALMS/824-885  AC A0A653BEQ3.1
#=GS A0A097R5N0_HAFAL/1-96     AC A0A097R5N0.1
#=GS A0A2I0FVL5_9GAMM/1-78     AC A0A2I0FVL5.1
#=GS A0A4Q1B805_9GAMM/1-80     AC A0A4Q1B805.1
#=GS A0A1X1ERD6_PANCY/1-75     AC A0A1X1ERD6.1
#=GS A0A1W6B204_9GAMM/1-76     AC A0A1W6B204.1
#=GS D4GKB2_PANAM/1-78         AC D4GKB2.1
#=GS A0A0M2KDQ3_9GAMM/1-76     AC A0A0M2KDQ3.1
#=GS A0A410DW03_9CLOT/292-367  AC A0A410DW03.1
#=GS A0A366I851_9GAMM/1-81     AC A0A366I851.1
#=GS A0A4P8YH88_9ENTR/1-77     AC A0A4P8YH88.1
#=GS V9H7N6_9CLOT/292-363      AC V9H7N6.1
#=GS A0A1I4WTN8_9GAMM/1-73     AC A0A1I4WTN8.1
#=GS A0A663B7G6_9ENTR/1-79     AC A0A663B7G6.1
#=GS D2TI37_CITRI/1-78         AC D2TI37.1
#=GS PBPB_ECOLI/1-79           AC P02919.2
#=GS PBPB_ECOLI/1-79           DR PDB; 5HL9 A; 68-79;
#=GS PBPB_ECOLI/1-79           DR PDB; 5HLB A; 67-79;
#=GS PBPB_ECOLI/1-79           DR PDB; 5HLD A; 73-79;
#=GS PBPB_ECOLI/1-79           DR PDB; 5HLA A; 67-79;
#=GS PBPB_ECOLI/1-79           DR PDB; 5FGZ A; 72-79;
#=GS PBPB_ECOLI/1-79           DR PDB; 6YN0 A; 74-79;
#=GS PBPB_ECOLI/1-79           DR PDB; 3FWL A; 66-79;
#=GS PBPB_ECOLI/1-79           DR PDB; 3VMA A; 72-79;
#=GS A0A2S4MSR0_SHIFL/1-79     AC A0A2S4MSR0.1
#=GS A0A4Z0NBP8_SALET/1-74     AC A0A4Z0NBP8.1
#=GS A0A257LXW1_9BACT/11-92    AC A0A257LXW1.1
#=GS A0A085JJP5_9GAMM/1-77     AC A0A085JJP5.1
#=GS W1EQT8_KLEPN/1-79         AC W1EQT8.1
#=GS D3V553_XENBS/1-81         AC D3V553.1
#=GS A0A0J8YQU7_9GAMM/1-80     AC A0A0J8YQU7.1
#=GS A0A250B3A8_9GAMM/1-85     AC A0A250B3A8.1
#=GS Q32JV9_SHIDS/1-79         AC Q32JV9.1
#=GS D3VL04_XENNA/1-86         AC D3VL04.1
#=GS G2H157_9ENTR/1-70         AC G2H157.1
#=GS W0LAW6_9GAMM/1-86         AC W0LAW6.1
#=GS H5V4C9_ATLHE/1-76         AC H5V4C9.1
#=GS A0A6I4V7N9_9GAMM/1-78     AC A0A6I4V7N9.1
#=GS A0A0A8VEQ6_YERRU/1-90     AC A0A0A8VEQ6.1
#=GS A0A2A2GQ98_9GAMM/1-80     AC A0A2A2GQ98.1
#=GS A0A417PSE7_9CLOT/283-365  AC A0A417PSE7.1
#=GS Q7N862_PHOLL/1-79         AC Q7N862.1
#=GS A0A085ABN8_9ENTR/1-79     AC A0A085ABN8.1
#=GS A0A2P8VHI8_9ENTR/1-81     AC A0A2P8VHI8.1
#=GS A0A370QPV3_9GAMM/2-53     AC A0A370QPV3.1
#=GS A9MPL2_SALAR/1-74         AC A9MPL2.1
#=GS A0A4R3Z2N8_9GAMM/1-85     AC A0A4R3Z2N8.1
#=GS A0A0L0AFX2_9ENTR/1-77     AC A0A0L0AFX2.1
#=GS A0A2D0KKD1_9GAMM/1-85     AC A0A2D0KKD1.1
#=GS Q6D1Y4_PECAS/1-81         AC Q6D1Y4.1
#=GS A0A370QPV3_9GAMM/50-100   AC A0A370QPV3.1
#=GS H3R8Q1_PANSE/1-81         AC H3R8Q1.1
#=GS A0A5P8YCB4_YERPE/1-82     AC A0A5P8YCB4.1
#=GS A0A4U5MJL0_STECR/2-67     AC A0A4U5MJL0.1
#=GS A0A4U2UQ35_9GAMM/1-79     AC A0A4U2UQ35.1
#=GS A0A085GNS5_9GAMM/1-102    AC A0A085GNS5.1
#=GS A0A396QKW8_9FIRM/292-372  AC A0A396QKW8.1
#=GS A0A443I8W1_9GAMM/1-83     AC A0A443I8W1.1
#=GS A0A3N1ISS2_9ENTR/1-78     AC A0A3N1ISS2.1
#=GS A0A0N0Z8D3_9GAMM/1-88     AC A0A0N0Z8D3.1
#=GS A0A378EB75_KLEPR/1-76     AC A0A378EB75.1
#=GS J7SKR5_MORMO/1-94         AC J7SKR5.1
#=GS A0A3B0JCH5_9GAMM/1-80     AC A0A3B0JCH5.1
#=GS K8W302_9GAMM/1-95         AC K8W302.1
#=GS V5AS83_ENTCL/1-75         AC V5AS83.1
#=GS A0A0U5KZP4_9GAMM/1-79     AC A0A0U5KZP4.1
#=GS A0A071LWQ4_9ENTR/1-84     AC A0A071LWQ4.1
#=GS A0A095V6S1_9GAMM/1-77     AC A0A095V6S1.1
#=GS A0A014N8J2_9GAMM/1-76     AC A0A014N8J2.1
#=GS A0A084A612_9GAMM/1-99     AC A0A084A612.1
A0A1H8XUY3_9PSEU/107-169             ....ddeayeg-----.---------------..-----.------....--EY.DEy...........eD.YDGEY..E...E....DDe..aY....EEP........A.EES..PSR...............GK...K.P.RKGR..K..R..KR.....A.LGW.VAALTVLVL--la..................
A0A089Q2B0_9ENTR/1-83                ...........MAGND.REPIGRKGKPT--RP..AKEKV.SRRRLK....EEDY.DD.............-.---EY..E...D....D-....D....YED........E.EPM.pPRKgk...........gkGK...G.S.GRPS..K..K..RR.....F.FWL.LVKLAIIFFVV....................
Q8ZRQ3_SALTY/1-74                    ...........MAGND.REPIGRKGKPS--RP..VKQKV.SRRRQH....DDDY.DD.............-.-----..-...-....--....D....YED........E.EPM..PRK...............GK...GkG.RKPR..G..K..RG.....W.LWL.LLKLFIVFVVL....................
A0A2X4TLC6_SALER/1-52                ...........MAGND.REPIGRKGKPS--RP..VKQKV.SRRRQH....DDDY.DD.............-.-----..-...-....--....D....YED........E.EPM..PRK...............GK...G.Q.R---..-..-..--.....-.---.-----------a...................
A0A4S2DRU8_9CLOT/292-360             .....apisnv-----.---------------..---KA.NKSSTI....EDDYyDD............dE.YDEEY..D...D....ED....Y....DDF........D.EDE..KPK...............NK...K.K.N-TK..K..K..IL.....IsIGI.IVGLLLL----asi.................
C5BH79_EDWI9/1-87                    ...........MSGDD.RQPIGRKGKKRAAQP..LRGEP.TRRRRRy..dEDDY.DE............dD.QERGE..S...D....DDg..yD....DDD........E.GDV..AHK...............--...Q.V.KRS-..R..R..RR.....V.LWL.LFRLALVALVV....................
B2VCM2_ERWT9/4-82                    ..........m--SDD.REPIGRKGKQP--QP..PRNKA.GRGRRR....EPQY.DD.............-.YDDQ-..-...D....HD...lD....DEE........I.TPV..PRK...............-A...K.A.RPAR..K..K..RG.....W.LGL.FIKLFLVFVV-a...................
A8ALE0_CITK8/1-78                    ...........MAGND.REPIGRKGKPP--RP..VKQKV.SRRRLR....DEEY.DD.............D.YDD--..-...-....--....D....YED........E.EPM..PRN...............GK...GkG.RKPR..G..K..RG.....W.LWL.LLKLSIVFVVL....................
A0A378C0Q6_KLEPO/1-32                ...........-----.---------------..-----.------....----.--.............-.-----..-...-....--....-....---........-.--M..PRKa.............kGK...G.G.K-PR..R..K..RS.....W.LWL.LVKLGIVFAVL....................
A0A0H3GIH5_KLEPH/1-79                ...........MAGDD.REPIGRKGRPS--RP..TKQKV.TRRRVR....EEDY.DD.............E.Y----..D...D....-D....D....YED........E.KPV..PRKa.............kGK...G.G.K-PR..R..K..RS.....W.LWL.LVKLGIVFAVL....................
A0A151UKV6_9GAMM/1-64                ...........MSGDD.REPIGRHGRPSG---..-RKAT.PR-RRR....DDD-.--.............-.-----..-...-....--....-....--K........E.YVM.pPRK...............GR...G.V.A-PR..K..K..YL.....L.LGW.LVHLVLLFVIV....................
A0A1B7JMM2_9GAMM/1-93                ...........MSGKDnNEPIGRRSKKAA--E..KKQSS.SRRRRD....RDDY.DDedl......leddD.IDDQY..L...D....D-....E....EDE........E.EQM..AKKg............skNK...K.T.RKVK..S..K..WR.....W.FWL.LVKLMVVFAVL....................
A0A3L7LR98_9GAMM/1-82                ...........MSGDD.REPIGRYGRPSGRKA..PRKAA.PR-RRR....DDDY.DD.............-.-DDRW..P...D....DD....E....DEE........E.YLM.pPRK...............GR...G.G.A-PR..K..K..RR.....L.LGW.LIRLLLLLVVV....................
A6T4V3_KLEP7/1-79                    ...........MAGDD.REPIGRKGRPS--RP..TKQKV.TRRRVR....EEDY.DD.............E.Y----..D...D....-D....D....YED........E.KPV..PRKa.............kGK...G.G.K-PR..R..K..RS.....W.LWL.LVKLGIVFAVL....................
H2IQ93_RAHAC/1-95                    ...........MSGDD.REPIGRKGKPAGRKP..ARARP.VRRSRR....DDDY.EEy..........eeE.IDDEY..E...D....DD....D....YEE........E.RESrmSRKapp.........rkaNK...G.G.KKS-..K..K..RR.....L.FWL.LVKLFVVFLIL....................
A0A3R8Z2R4_9GAMM/1-76                ..........m--SDD.REPIGRKGKQP--NP..PRKTA.GRGRRR....DVDN.ID.............-.F---Q..D...D....DH....N....NEE........K.VPV..PRK...............GK...G.-.RPP-..R..K..RG.....W.LSL.MIKLLLVFIVL....................
J2XC22_KLEPN/1-79                    ...........MAGDD.REPIGRKGRPS--RP..TKQKV.TRRRVR....EEDY.DD.............E.Y----..D...D....-D....D....YED........E.KPV..PRKa.............kGK...G.G.K-PR..R..K..RS.....W.LWL.LVKLGIVFAVL....................
A0A6M8U5G6_9GAMM/1-81                ...........MSGND.REPIGRKGKQP--KP..PRKTA.GRGRRR....-DDY.DN.............-.YDDDQ..D...D....FD...dE....YEE........V.EPV..PRK...............GK...-.R.RPPS..K..K..RG.....W.LGL.FIKLFLIFVVL....................
D8MNB6_ERWBE/1-80                    ..........m--SDD.REPIGRKGKQP--KP..PRKVA.GKGRRR....DDEH.DD.............-.YDDFQ..D...D....DH....E....NEE........V.EPV..PRK...............GK...G.-.RPPG..K..K..RG.....W.LSL.LIKLLLVFIVV....................
A0A2T0BJT0_9CLOT/294-359             avnlpsdnipi-----.---------------..-----.--NKDL....DEDY.DD.............E.DDDYY..D...D....ED....D....DEE........K.RRK..PKK...............KK...-.K.--KS..N..K..NL.....I.IGI.IIAIVLLIA--gv..................
A0A0Q4MV86_9GAMM/1-78                ..........m--SDD.REPIGRKGKQP--KP..PRSTA.GRGRRR....EDE-.DD.............-.YD--R..-...D....DE....Q....EEE........V.TPV..PRK...............GK...G.KgSTPR..K..R..RG.....W.FWL.LVKLLVIFAVL....................
A0A2I8Q8F4_9ENTR/1-78                ...........MAGND.REPIGRKSRPS--RP..AKEKV.SRRRVR....EEEY.DE.............-.----Y..D...D....-D....D....GDE........Q.ESA..PRKg.............kGK...G.G.K-PR..G..K..RR.....W.FWL.LLKICIVGAVL....................
A0A2I5T5M1_SERS3/1-86                ...........MSRDD.REPIGRKGNTSRRKP..TRKQT.VR-RHR....DDDY.DD.............D.YDEYD..D...D....YDn.ddD....GDG........D.GDD..NGK...............N-...M.T.RKPR..K..K..RR.....W.LGL.MIKLSLIFAVV....................
A0A4R1NHN5_9GAMM/1-79                ...........MSGDD.REPIGRHGRPSDRKV..PRRQP.VRSRRD....DDDE.D-.............-.---DQ..E...D....Y-....D....DEE........E.KVM..PPH...............KG...K.S.RPPR..K..R..RR.....L.LGW.MIRIFILLIIL....................
A0A0B7GFW7_KLEVA/1-79                ...........MAGDD.REPIGRKGRPS--RP..TKQKV.TRRRVR....EEDY.DD.............E.Y----..D...D....-D....D....YED........E.KPV..PRK...............GK...G.NgGKPR..R..K..RR.....W.LWL.LVKLGIVFAVL....................
D2U404_9GAMM/1-81                    ........mfd--KDN.YEPIGRKSKKKSTG-..-KKSK.SQQNNR....LDN-.--.............-.YDYEY..E...D....ID....D....SEE........E.ELM..ANK...............DN...K.S.RPAK.nN..R..WR.....W.FWL.FVKIAIVLALL....................
A0A4R6ELG8_9ENTR/1-77                ...........MAGND.REPIGRKGKPA--RP..AKQKV.SRRRLR....DEEY.DD.............-.--DDY..-...-....--....D....DED........E.EPM..PRN...............GK...GkG.KKPR..R..K..YG.....W.FWL.LVKLGIVFAVL....................
A0A090UZ74_PSEVU/1-79                ...........MAGND.REPIGRKGRPA--RP..VKEKV.SRRRLR....DEEM.DD.............A.-----..-...-....--....Y....DED........D.APA..PRRgk..........gggNG...K.G.KGGK..R..K..RG.....W.FWL.LLKIFIVLLVL....................
A0A6B2FQE1_9ENTR/1-78                ...........MAGND.REPIGRKGRPG--RP..VNEKA.SRRRLR....EEQY.DD.............E.Y----..D...D....-D....D....YDD........E.EPM..PRK...............VK...K.G.RTPR..K..K..RS.....W.LWF.LLKLLIVLLVI....................
A0A0J5LVU0_PLUGE/1-79                ...........MAGND.REPIGRKGKKP-ARP..AKQKV.SRRRLR....DDEY.DD.............E.YEYD-..-...-....--....-....DED........D.APM..PRKg.............kGK...G.N.-RPR..G..K..RG.....W.FWL.LVKLGIVFAVL....................
A0A0L7SZB5_9GAMM/1-82                ...........MSGND.REPIGRKGKQP--K-..PPRKP.AKGRRR....EEDY.NE.............D.YDDYQ..D...D....TD....D....DHE........EtEPV..PRK...............A-...K.G.RSPR..K..K..RG.....W.LGL.IIKLLLVVIVL....................
A0A6L2ZMW4_9ENTR/1-71                ...........MSEDH.RNPTGRKKRKSVTNT..EPKKP.LH--RR....DDD-.-E.............-.-----..-...-....-N....N....AED........N.KSM..RKK...............-E...K.S.RLMR..K..K..RY.....W.FGL.FVKLFLMIAL-l...................
A0A6L6IE98_9ESCH/1-78                ...........MAGND.REPIGRKGRPS--RP..AKQKV.SRRRLK....DDEY.DD.............D.YDD--..-...-....--....D....YED........E.KPM..PRK...............GK...GkG.RKPR..G..K..RG.....W.LWL.LLKLLIVFVVL....................
A0A085GJ62_9ENTR/10-90               ...........MAGND.REPIGRKGKPS--RP..AKEKV.SRRRVR....EEEY.DA.............D.YDDD-..-...-....--....-....YDD........E.EPM.pPRK...............GKgsgN.G.RPPR..K..K..RR.....W.LWF.LVKLFVVFVVL....................
A0A2Y9CKA9_9GAMM/1-82                ..msrndrnpl----D.RDPIGRKKRKSISNP..KQKKP.SA-RRR....DDD-.EE.............N.FLEE-..-...-....--....-....GDE........E.QES..MRS...............KK...K.S.SPVR..K..K..RR.....W.LGL.SIKLFLVIVLL....................
A0A0J8YWE8_9GAMM/1-78                ...........MSGND.REPIGRKGKSTPKGK..SPPAS.PRNKKY....QDDP.DS.............-.----Y..-...-....--....D....DEE........N.TSL..PAT...............KK...R.G.KTPR..KshK..RS.....W.LGL.LLKIILVIAVI....................
A0A0J8VNI1_9ENTR/1-81                ...........MAGND.REPIGRKGRPA--RP..VKEKV.SRRRLR....EEEY.DD.............E.YEDEE..P...A....PR....T....A--........-.---..--Kgrg.........nggGG...K.G.RKPA..K..K..RR.....W.LWF.LLKLFLILVVV....................
W0HML6_9GAMM/1-74                    ...........MSGDD.REPIGRHGRPSGRKA..PRKAA.PR-RRR....DDDY.DD.............-.-----..-...-....--....D....DEE........E.YVM.pPRK...............ER...G.G.-APR..K..K..RR.....L.LGW.FIRLVLLFVVV....................
Q8X903_ECO57/1-79                    ...........MAGND.REPIGRKGKPT--RP..VKQKV.SR-RRY....EDD-.--.............-.--DDY..D...D....YD....D....YED........E.EPM..PRK...............GKgkgK.G.RKPR..G..K..RG.....W.LWL.LLKLAIVFAVL....................
E3G929_ENTLS/1-78                    ...........MAGND.REPIGRKGKPA--RP..AKQKI.SRRQLR....EEEY.DD.............E.YDE--..-...-....--....D....DEE........D.DSM..PRK...............GK...GkG.RKPR..G..K..RG.....W.FWL.LVKLGIVFAVI....................
D4E1W8_SEROD/1-86                    ...........MAGDD.REPIGRKGKQPKRS-..ASRKP.LR-RRR....DDDY.DDfe.........adD.YQDEY..E...D....ED....Y....DDQ........E.QRM..PRK...............-V...K.A.APPR..K..K..RR.....W.LGL.IVKIILVIAVL....................
A0A1X0WKI7_9GAMM/1-99                ...........MSGDD.REPIGRKGKPSPPKP..KRGRP.VR-RSR....DDEE.ET.............R.YSYQG..D...D....EQ....D....DDDvsrnaapqE.SRM.tPRKtak.........ggkAG...N.G.KKPR..K..K..RR.....W.FGL.LIKLFIIFVVL....................
A0A6L6HCS0_9GAMM/1-78                ...........MAGND.REPIGRKGKPK--RP..PEKKV.SRRRLR....DERY.DD.............-.-----..D...D....YD....D....DDD........E.APM..SRK..............vKK...K.G.RPPR..R..K..RS.....W.IWF.FIKLLIVLLVL....................
E0SBK6_DICD3/1-81                    ...........MSRDD.REPIGRKRSASRHTP..PRKQA.TR-RRR....DDDY.DD.............D.YEEEY..EedyD....DD....E....DDE........E.EVM..SKR...............--...-.-.--PR..K..K..RR.....W.LGL.LIRLFLIFVVV....................
L0MAA6_ENTBF/1-79                    ...........MAGND.REPIGRKGKPA--RP..AKQKV.SRRRLR....DEEY.DD.............D.YDDDY..-...-....--....-....-ED........D.EPM.pPRKg.............kGK...G.G.K-PR..R..K..HG.....W.FWL.LVKLAIVFAVL....................
A0A249WEU6_9ENTR/1-80                ...........MAGDD.REPIGRKGRPS--RP..AKQKV.TRRRVR....EEDY.DD.............D.Y----..D...D....-D....D....YED........E.KPM..PRKg.............kGK...G.G.KPPR..R..K..RA.....W.LWL.LIKIGVVCAVL....................
T0QJE5_PHOTE/1-83                    ...........MSGED.RRPIGRKGKKPVS--..RREPL.SKRRHL....LDDN.-D.............N.YDDGY..E...D....DD...yD....DEE........D.QPM..TKR...............GK...N.S.RPPK..K..K..WC.....W.FWL.LFKIFIVFAVL....................
A0A381H8Y6_CITKO/1-37                ...........MAGND.REPIGRKGKPP--RP..VKQKV.SRRRLR....DEEY.DE.............-.-----..-...-....--....-....---........-.---..---...............--...-.-.----..-..-..--.....-.---.-----------rl..................
A0A2N5EKD4_9GAMM/1-88                ...........MSGDD.REPIGRKGKTPPPVR..KPLRQ.RPRNRR....DEDV.EEi..........edD.VEAGM..A...E....QD...nV....NKG........K.QRM..PRK...............VK...A.G.K-PR..K..K..RG.....W.LGL.LVKIGIVLAV-g...................
A0A5J5FRE0_9GAMM/1-82                ...........MARDD.REPIGRKGRRSGRKS..ERQPA.QR-RRG....EDDY.DD.............D.YDDDE..Y...DdyqdDD....D....PDD........E.DVM..AQK...............--...-.-.--PR..K..K..RR.....W.LGL.IVKLILVFVVL....................
A0A2V1HAJ6_9GAMM/1-93                ...........MAGDD.RKPIGRQGRQAKRH-..APRRP.MR-RRR....DDDY.DEydeye..edeyqdE.YDDDE..D...D....YD....E....EYE........E.KRM..PRK...............VK...A.H.S-SR..K..K..RR.....W.LWL.LFKLFLVVAA-l...................
A0A421DMJ5_9GAMM/1-87                ...........MSRDD.REPIGRKGKASGRKP..ARRQA.VR-RRR....DDDY.DDd..........yeD.YQDDF..D...D....DD....D....GYD........D.DGY..DGE...............GR...M.T.RKPR..K..K..RR.....W.LGL.FIKLALVFAVL....................
A0A0G4JX91_9GAMM/1-82                ...........MSRDD.REPIGRKGKTSRRKP..ARRQE.VR-RRR....DDDY.DD.............D.YEDYQ..D...D....FD....DdddgYDD........E.DAM..TNK...............--...-.-.--PR..K..K..RR.....W.LGL.FIKLALIFAVL....................
A0A1H4EB36_9GAMM/1-76                ...........MARDD.REPIGRKGKAP-RKP..TRKQV.VRRRRD....DDDY.DD.............D.YE-EY..D...D....Y-....D....DED........D.EEM..SRK...............--...-.-.--PG..K..K..RR.....W.LGL.ALKLLLVFVVV....................
A0A240CCL5_SERFI/1-82                ...........MAGDD.REPIGRKGKQPKRTA..SR-KP.PR-RRR....DDDY.DD.............Y.EEDEY..D...D....DE....Y....QEE........E.ERM..PRK...............-V...K.A.TPPR..K..K..RR.....W.LGL.MIKLILVIAVL....................
U3TMS9_9ENTR/1-80                    ...........MSGND.REPIGRKGKAP--KP..PRNVT.RRGRRRe..pEDDI.DQ.............-.-----..D...D....FD...eD....DEE........S.APV..PPK...............GK...G.K.RPAR..G..K..RR.....W.LGW.LIKLFLVFVVV....................
A0A5R9LF42_9ENTR/1-80                ...........MAGDD.REPIGRKGRPS--RP..TKQKV.TRRRVR....EENY.DD.............D.Y----..D...D....-D....D....YED........E.KPM..PRKg.............rGK...G.G.KPPR..R..K..RT.....W.LWL.LIKIGIVCAVV....................
A0A2S6VPU4_9GAMM/1-82                ...........MSGND.REPIGRKGKAP--KP..PRTTA.RRGHRK....EPDG.H-.............-.IGQ-T..D...I....DE....D....YEE........S.APV..PPKs.............kGR...G.K.GPQR..G..K..RR.....W.LGW.LIKLFLVVVVV....................
W1DUE4_KLEPN/1-79                    ...........MAGDD.REPIGRKGRPS--RP..TKQKV.TRRRVR....EEDY.DD.............E.Y----..D...D....-D....D....YED........E.KPV..PRKa.............kGK...G.G.K-PR..R..K..RS.....W.LWL.LVKLGIVFAVL....................
E9CN74_9GAMM/1-75                    ...........MAGDN.REPIGRKEKQPK---..--RTA.SR--RR....RDDY.DN.............-.-QDLY..D...D....DV....G....KQE........E.EPM..PRK...............-V...K.A.TPPH..K..K..RR.....W.LGL.MIKLLLVIAA-l...................
A0A068YVW8_9GAMM/1-75                ...........MAGDN.REPIGRKEKQPK---..--CTA.S--RRR....RDDY.DN.............-.-QDLY..D...D....DV....G....KQE........E.EPM..PRK...............-V...K.A.TPPH..K..K..RR.....W.LGL.MIKLLLVIAA-l...................
A0A2G8E8T3_9GAMM/1-76                ...........MSGND.RQPIGRKGKQP--RP..PRKRA.QHGRQT....EDEY.DD.............-.-----..I...D....DE....Q....EEE........V.TSV..PRK...............GR...G.G.P-PG..R..K..RR.....W.LGL.FIKLFLIFIVV....................
I2BCM2_SHIBC/1-89                    ...........MAGND.REPIGRKGKPT--RP..GKEKV.SRRRLR....EEDY.DD.............D.YQDDE..D...D....YD....D....DYD........E.QPV..SRKkmt.........gkrGK...N.G.RPPR..R..K..RR.....L.LWF.LVKLFIIGVVL....................
W1I1F0_KLEPN/1-79                    ...........MAGDD.REPIGRKGRPS--RP..TKQKV.TRRRVR....EEDY.DD.............E.Y----..D...D....-D....D....YED........E.KPV..PRKa.............kGK...G.G.K-PR..R..K..RS.....W.LWL.LVKLGIVFAVL....................
W1J9U1_9GAMM/1-82                    ...........MSDDD.RQPIGRKGKKSGHRR..GRQAN.KRHRRD....DYDY.DD.............-.FEDES..-...-....-N....N....DDE........N.EVM..TKK...............GN...K.S.PQVK..R..R..GK.....W.VWLlLLKIFIVLTVL....................
W0I1G7_9GAMM/1-83                    ...........MSGDD.REPIGRHGRPSGRKA..PRKAA.PR-RRR....DDDY.DD.............-.-DDRW..Q...D....DD....D....DDE........E.EYVmpPRK...............GR...G.G.A-PR..K..K..RR.....L.LGW.VIRLVLLFVVV....................
A0A653BEQ3_CALMS/824-885             .eattpsiaeg-----.---------------..-----.---RVP....DEEY.DD.............-.---DY..E...D....--....D....YED........E.EPM..PRK...............GK...GkG.RKPR..G..K..RG.....W.FWL.LLKLFIVFVVL....................
A0A097R5N0_HAFAL/1-96                ........msr--DDD.REPIGRKGKKGGTPP..SRKAV.PNRRRRyddeDDDY.RD.............D.FRDTA..D...D....HD....D....YEE........D.DDY..DDEdre.........ddvAR...K.K.VKKS..R..K..RK.....L.LGL.LIKLALIVFVL....................
A0A2I0FVL5_9GAMM/1-78                ...........MSGND.REPIGRKGKAP--TP..PRKNA.VKGRRR....DDDY.DD.............-.---EY..Q...D....DD....D....DEE........D.VVM..PRN...............GK...K.G.T-PR..K..K..RR.....W.LGL.FIKLMLVFVVL....................
A0A4Q1B805_9GAMM/1-80                .......mhdk---DN.YGPIGRRSKKKP-S-..GKKSK.SHQNNR....SDN-.--.............-.YDYEY..E...D....ID....D....NEE........E.ELM..ASK...............DN...K.S.RPPK..D..R..WR.....W.FWL.FVKITIVLALL....................
A0A1X1ERD6_PANCY/1-75                ...........MSGND.REPIGRKGKQP--KP..PRSIA.RRGRRR....ELD-.DD.............-.---T-..-...-....EQ....D....DEE........S.EPV..PRK...............GK...G.K.RPPR..A..K..RR.....W.LGW.FIKLFLVFVVV....................
A0A1W6B204_9GAMM/1-76                ...........MSGND.REPIGRKGKQP--KP..PRQSG.GPGRRR....E-EY.ND.............-.-----..E...E....HD....D....YQE........E.RPV..PRK...............GK...G.R.PPRS..K..K..RK.....W.LGW.LIKLFIVFVVV....................
D4GKB2_PANAM/1-78                    ...........MSGND.REPIGRKGKPL---P..PRSSA.RRGRRR....D--I.DD.............D.AQDDF..D...D....--....D....YEE........E.APV..PRK...............GK...G.G.KPPR..G..K..RR.....W.LGW.LIKLFLVFVVV....................
A0A0M2KDQ3_9GAMM/1-76                ..........m--SDD.REPIGRKGKKP--NP..PRSPA.GRGKRR....DDD-.-E.............D.FQ---..D...D....DH....D....NEE........R.QSV..PRN...............GK...G.R.S-PR..R..R..RG.....W.LGL.FVKPALVFIL-v...................
A0A410DW03_9CLOT/292-367             .mepvtaevik-----.---------QAALK-..NKAKA.QS-KVY....DEDE.EN.............E.DDDDY..Y...D....DD....E....DDD........E.KLT..PKQ...............-K...K.Q.R--V..I..N..RV.....L.LGL.AFVLIVVVAI-a...................
A0A366I851_9GAMM/1-81                ...........MSRDD.REPIGRKGRASGRKP..TRRQA.IR-RHR....DDDY.DD.............D.YEDDQ..D...D....FN....Dd.drYDD........E.DSM..TQK...............--...-.-.--PR..K..K..RR.....W.LGL.FIKLSLVFAVV....................
A0A4P8YH88_9ENTR/1-77                ...........MAGND.REPIGRKGKPK--RP..PKEKV.SRRRLR....DERY.DD.............-.-----..D...D....ND....D....DFD........E.APM..SRK...............VK...K.G.RPPR..R..K..RS.....W.IWF.FVKLMIVLLVL....................
V9H7N6_9CLOT/292-363                 ......tpint-----.---------------..QNQKT.NHSSKL....EDDY.DEe...........dD.YDEDE..D...F....DD...dY....DED........E.DEL..PKK...............KK...S.K.NGVK..K..A..IV.....T.IGV.IIGVIILG---sv..................
A0A1I4WTN8_9GAMM/1-73                ...........MSGND.REPIGRKGKQP--KP..PRSRV.RWGRRK....EEDY.AD.............-.-----..-...-....-D....D....DEE........V.TFV..PRK...............GK...G.G.P-RG..G..K..RR.....W.LGL.FIKLFLLLIVI....................
A0A663B7G6_9ENTR/1-79                ...........MAGDD.REPIGRKGRPS--RP..TKQKV.TRRRVR....EEDY.DD.............E.Y----..D...D....-D....D....YED........E.KPV..PRKa.............kGK...G.G.K-PR..R..K..RS.....W.LWL.LVKLGIVFAVL....................
D2TI37_CITRI/1-78                    ...........MAGND.REPIGRKGKPS--RP..VKQKV.SRRQLR....DDEY.DD.............E.YDD--..-...-....--....D....YED........E.EPM..PRK...............GK...GkG.RKPR..G..K..RG.....W.LWL.LLKIAIVFLVL....................
PBPB_ECOLI/1-79                      ...........MAGND.REPIGRKGKPT--RP..VKQKV.SR-RRY....EDD-.--.............-.--DDY..D...D....YD....D....YED........E.EPM..PRK...............GKgkgK.G.RKPR..G..K..RG.....W.LWL.LLKLAIVFAVL....................
#=GR PBPB_ECOLI/1-79           SS    ...........XXXXX.XXXXXXXXXXX--XX..XXXXX.XX-XXX....XXX-.--.............-.--XXX..X...X....XX....X....XXX........X.XXX..XXX...............XXXXXX.X.XXXX..X..X..XX.....X.XXX.THHHHHHHHHH....................
A0A2S4MSR0_SHIFL/1-79                ...........MAGND.REPIGRKGKPT--RP..VKQKV.SR-RRY....EDD-.--.............-.--DDY..D...D....YD....D....YED........E.EPM..PRK...............GKgkgK.G.RKPR..G..K..RG.....W.LWL.LLKLAIVFAVL....................
A0A4Z0NBP8_SALET/1-74                ...........MAGND.REPIGRKGKPS--RP..VKQKV.SRRRQH....DDDY.DD.............-.-----..-...-....--....D....YED........E.EPM..PRK...............GK...GkG.RKPR..G..K..RG.....W.LWL.LLKLFIVFVVL....................
A0A257LXW1_9BACT/11-92               .........cg----D.EVPIGPRGCPKCTKPpkPRKKA.QRPSWE....QDKY.LD.............D.LDLPN..E...D....FD....Y....D--........-.EFV..ARE...............--...F.G.KKPH..R..KigIK.....W.YWW.VTALVLLVLII....................
A0A085JJP5_9GAMM/1-77                ...........MSGND.REPIGRKGKTP-RQP..EKKRP.RAKSKN....SKAY.DD.............-.-----..H...E....MS....G....YEE........E.VAL..SRK...............GK...K.-.KPPM..K..K..RR.....W.LGW.LIKLFLLGAIV....................
W1EQT8_KLEPN/1-79                    ...........MAGDD.REPIGRKGRPS--RP..TKQKV.TRRRVR....EEDY.DD.............E.Y----..D...D....-D....D....YED........E.KPV..PRKa.............kGK...G.G.K-PR..R..K..RS.....W.LWL.LVKLGIVFAVL....................
D3V553_XENBS/1-81                    ...........MSDDD.RQPIGRKGKKPELR-..-RERP.AKKRHR....QDDY.EN.............-.--DEN..N...D....FD....N....DDE........E.QVM..TKK...............GK...K.P.RPPR..S..R..WR.....G.FWLlLLKIFIVLAVL....................
A0A0J8YQU7_9GAMM/1-80                ..........m--SDD.REPIGRKGKQP--KP..PRNKA.GRGRRR...eEEEY.DE.............-.YDDQ-..D...D....DL....D....DEE........V.TPV..PRK...............GK...G.R.S-PR..K..K..RG.....W.IGL.LIKLFLLFAVV....................
A0A250B3A8_9GAMM/1-85                ...........MAGDD.REPIGRKGKQPKRS-..TPRRP.LRGRRD...dYDDY.EE............dE.YQDEY..D...D....DE....K....DDE........E.APM..SRK...............-V...K.A.APPR..K..K..RR.....W.LGL.IIKLLLVIAVL....................
Q32JV9_SHIDS/1-79                    ...........MVGND.REPIGRKGKPT--RP..VKQKV.SR-RRY....EDD-.--.............-.--DDY..D...D....YD....D....YED........E.EPM..PRK...............GKgkdK.G.RKPR..G..K..RG.....W.LWL.LLKLAIVFAVL....................
D3VL04_XENNA/1-86                    ...........MSDDD.RQPIGRKGKKSGLR-..-RGRA.SKNRVR....QDDY.DD.............-.--YEN..D...D....FD....D....DDE........D.EVM..TKK...............GK...N.A.RSPK..S..R..SSknrgnWiLWF.LLKVFIVLAVI....................
G2H157_9ENTR/1-70                    ...........MSEDH.RNPTGRKKPKSVTNT..EPKKP.LH--RR....DDE-.--.............-.-----..-...-....-N....N....AED........N.KSM..RKK...............-E...K.S.RLIH..K..K..RY.....W.FGL.FVKLFLMIAL-l...................
W0LAW6_9GAMM/1-86                    ...........MAGDD.REPIGRKGKQAK-RN..APRKP.VR-RRR....EDDY.DDye.........ddD.YQDEY..D...D....DE....Y....DDE........E.EPV..PRK...............V-...K.A.RSPR..K..K..RR.....W.LGL.MIKLFLVVAV-a...................
H5V4C9_ATLHE/1-76                    ...........MAGND.REPIGRKGKPS--RP..VKQKV.TRRRLR....EDEY.DD.............-.-----..-...D....YE....D....DDN........E.EPM.pPRK...............GK...G.K.K-PQ..R..K..RR.....W.LWL.LLKLMLVLIVV....................
A0A6I4V7N9_9GAMM/1-78                ...........MSGND.REPIGRKGKPL---P..PRSSA.RRGRRR....D--I.EQ.............-.-NIDQ..D...D....FN....D....DEE........E.APV..PRK...............GK...G.R.KPPR..G..K..RR.....W.LGW.LIKLFLVFVVV....................
A0A0A8VEQ6_YERRU/1-90                ..........m--SDD.REPTGRKGKKPAAKA..APKRP.LRRRRD....EDDY.DEdyl.......ddnD.RDDDE..D...S....YD...dD....DDE........D.QPM..PRK...............-V...K.S.TPAR..K..K..RR.....W.LGL.LIKLFIVAVVL....................
A0A2A2GQ98_9GAMM/1-80                .......mydk---DN.YEPIGRRSKKKP-TG..KKSKS.HQ-NNR....LDN-.--.............-.YDYEY..E...D....ID....D....NEE........E.ELM..ASK...............DN...K.S.RPPK..D..R..WR.....W.FWL.FVKIAIVLALL....................
A0A417PSE7_9CLOT/283-365             ....vdeqart-----.--VVMNKGTSSKIRN..SRKVE.VPASRDe..dEDEE.DD.............E.YEDDE..D...D....ED....E....DDD........E.ELS..PAV...............EK...A.M.----..-..-..--.....-.---.-----------tvagvvlaviivlivlllv.
Q7N862_PHOLL/1-79                    ...........MSGED.RQPIGRKGKKW---V..SRRKR.SIKRRY...lLDD-.D-.............-.--NGY..E...D....ED...yD....DEE........D.QLM..TKK...............GM...Y.S.RPPK..K..K..WR.....W.FWL.LFKIFIIFAVL....................
A0A085ABN8_9ENTR/1-79                ...........MAGND.REPIGRKGRPA--RP..AKEKI.SRRRLR....EEEY.DD.............-.---EY..D...D....Y-....D....DED........E.EPM..PRK...............GR...GrG.RKPR..G..K..RG.....W.FWL.LVKICIVLAVL....................
A0A2P8VHI8_9ENTR/1-81                ...........MAGND.REPIGRKGKPA--RP..AKQKV.SRRQLR....DDER.DD.............D.YEND-..-...-....--....D....YDD........G.EPM..PRKv.............kGK...G.R.KSGK..G..K.gRK.....W.LWL.LLKLFIVFVVL....................
A0A370QPV3_9GAMM/2-53                ...........MSGDD.REPIGRKGNKRRSAP..PRRQApERRRPR....YDDD.DD.............D.YRDDF..R...D....DD....D....DD-........-.---..---...............--...-.-.----..-..-..--.....-.---.-----------r...................
A9MPL2_SALAR/1-74                    ...........MAGND.REPIGRKGKPS--RP..VKQKV.SRRRQH....DDDY.DD.............-.-----..-...-....--....D....YED........E.EPM..PRK...............GK...GkG.RKPR..G..K..RG.....W.LWL.LLKLFIVFVVL....................
A0A4R3Z2N8_9GAMM/1-85                ...........MSGDD.REPIGRHGKPPARKP..TRKPF.-FGRKR....QDDY.DR.............N.NHDFQ..D...D....DD....Y....VHE........E.KAV.vPRQ...............KG...S.A.RPPR..K..R..RR.....L.LGL.IIKVFVVLVIL....................
A0A0L0AFX2_9ENTR/1-77                ...........MAGND.REPIGRKGKPA--RP..AKQKV.TRRQQY....DDDY.DD.............-.---EE..D...D....--....V....PPP........R.KTR..SKG...............NG...G.G.RKRR..G..K..RG.....W.LWL.LLKIFIVFVVL....................
A0A2D0KKD1_9GAMM/1-85                ...........MSDDD.RQPIGRKDKKSKHR-..-RGRQ.ANKRHR....RDDY.DD............yE.YNDVE..D...E....ND....T....NDE........G.ELM..TKK...............GK...K.S.PQVK..K..G..RK.....W.IWLlLLKILIVLAVL....................
Q6D1Y4_PECAS/1-81                    ...........MSQDD.REPIGRKGKAPKRKP..ERKQA.IR-RRR....DDDY.DDd..........ydD.YQDDY..D...D....DD....D....YDG........D.DTM..TRK...............--...-.-.--SQ..R..R..RR.....W.LGL.AIKLFLIFAV-a...................
A0A370QPV3_9GAMM/50-100              ..........d-----.---------------..-----.------....DDRY.DD.............-.-DDRY..D...D....DD....D....YDD........E.EDV..ARK...............-K...P.K.K-S-..R..K..RR.....L.LCL.LAKLALIVI--avl.................
H3R8Q1_PANSE/1-81                    ...........MSGND.REPIGRKGKPL---P..PRNSA.RRGRRR....DIDS.DV.............-.AQ---..D...D....FD...dD....YEE........E.APV..PRKg.............kGK...G.G.KPPR..G..K..RR.....W.LGW.FIKLFLVFVVV....................
A0A5P8YCB4_YERPE/1-82                ...........MSGDD.REPIGRKGKKAQPKA..APKRP.LRRRRD....EDEY.EE.............D.YDEEQ..N...D....--....Y....DDE........E.EPM..PRK...............-V...A.S.RPPR..K..K..RR.....W.LGL.LIKLFLIGAV-a...................
A0A4U5MJL0_STECR/2-67                sktaptteplk-----.---------------..-----.-----S....QRDI.ED............gD.AEKTC..R...D....ND....E....DEE........D.AKK..TKK...............-K...K.V.KLSK..K..Q..KI.....L.VGL.FVVLFLVCLIL....................
A0A4U2UQ35_9GAMM/1-79                ...........MSGDD.REPIGRHERPSDRKS..KRRPA.ARRRRD....DDDR.DD.............-.----Y..H...D....YN....-....DEE........E.QSM.pPRK...............-G...K.P.RPPR..K..K..RR.....L.TGL.LIKIFLLFAVV....................
A0A085GNS5_9GAMM/1-102               ...........MSGDD.REPIGRKGKPAGRKP..SRSRP.VR-RRR....DDDY.EEf..........ddD.YEEDR..E...T....DD....D....YDD........E.EDT..RREsrmsrkaaprkaaksGK...G.G.KPRS..R..K..RW.....W.FWL.LFKLFIIFAIL....................
A0A396QKW8_9FIRM/292-372             ...........MSDRE.MEEI-RAGMTSSTKP..VSSKT.SRYDDY....DDDE.DE............eD.YEDDI..D...D....DE....D....DDD........D.AVS..SKL...............EK...A.-.----..-..-..--.....-.---.-----------itiggfligaviiiilivvi
A0A443I8W1_9GAMM/1-83                ...........MSGND.REPIGRKGKQS--SP..PRKPA.GRGRRR....EDDY.DE.............K.FEDYQ..D...D....PD...nD....NEE........I.EPV..PRK...............GK...G.R.S-PR..K..K..RG.....W.LGL.IIKLLLIFIV-a...................
A0A3N1ISS2_9ENTR/1-78                ...........MAGND.REPIGRKGRTT--RP..AKEKV.SRRQLR....DEEY.DD.............D.YE---..-...D....--....D....DED........E.EPM..PRK...............GK...GkG.RGPR..G..K..RG.....W.FWL.LLKIGIVFAVL....................
A0A0N0Z8D3_9GAMM/1-88                ...........MSGKD.FEPIGKRKKTR--PT..KKPAN.SRRRQR....RDDY.DE............sP.FDDEQfnE...H....TE....Y....QQE........D.ELM..AKK...............SK...K.G.RPNKqkS..K..WR.....W.FWL.LVKIALVITL-l...................
A0A378EB75_KLEPR/1-76                ...........MAGDD.REPIGRKGRPS--RP..TKQKV.TRRRVR....EEDY.DD.............E.Y----..D...D....-D....D....YED........E.KPV..PRKa.............kGK...G.G.K-PR..R..K..RS.....W.LWL.LVKLGL-----ss..................
J7SKR5_MORMO/1-94                    ...........MSDFD.REPTGRRGSKASAGK..KRGRS.DRRRRR....DEDY.DDdie.......yddE.FGDDE..P...D....DD....D....YDD........E.EDS..PRMs............kkGR...K.N.KPPK..R..R..WR.....W.FWF.LVKLGIVMAIL....................
A0A3B0JCH5_9GAMM/1-80                .......mhdk---DN.YEPIGRRSKKKP-TG..KKSKS.HQ-NNR....LDN-.--.............-.YDYEY..E...D....LD....D....NEE........E.ELM..ASK...............DN...K.S.RPPK..N..R..WR.....W.FWS.FVKIAIVLALL....................
K8W302_9GAMM/1-95                    ...........MSGKD.LEPIGRRKKPVKQK-..-KKPN.SRRRRE....RDDY.EEy..........ddElFDNDD..I...D....EQn..lD....DEE........N.ELM..AKKrqs.........nkkSN...K.N.RSPK..S..K..WR.....W.FWL.LVKIFIVFAVL....................
V5AS83_ENTCL/1-75                    ...........MAGND.REPIGRKGKPA--RP..AKEKI.SRRRVR....DEEY.DE.............-.----Y..-...-....--....D....DEE........E.NAV..PKK...............GR...GrG.KKPR..G..K..RG.....W.FWL.LLKIFIVCAVL....................
A0A0U5KZP4_9GAMM/1-79                ...........MSGDD.REPIGRKGKSS--TP..PRKPA.VKGRRR....ERE-.EE.............-.--NVQ..D...D....FD....N....DEE........EvAPM..PRK...............GK...-.G.RPPV..K..K..RR.....W.LGL.LIKLFLVFVV-a...................
A0A071LWQ4_9ENTR/1-84                ...........MAGND.REPIGRKPKSG--RP..SKPKA.SRRGHR....DDDY.DD.............D.YDD-Y..D...D....EY....E....DED........E.EPMpsKRK...............GK...K.K.SPPG..K..K..RW.....L.LWL.LVKLFIIFAVI....................
A0A095V6S1_9GAMM/1-77                ...........MSGND.REPIGRKGKTPRQTE..KARKP.A-KRNK....NSHY.DD.............-.-----..Q...D....IN....E....YAE........E.QSL..PRK...............GK...K.-.KPPV..K..K..RR.....W.LGL.FIKLFLVAAVV....................
A0A014N8J2_9GAMM/1-76                ..........m--SDD.REPIGRKGKQP--NP..PRKVA.GRRERR....DDD-.-D.............D.FQDDG..-...-....-Y....D....HEE........K.KPV..PRK...............GK...G.R.S-PR..R..K..RG.....W.LGL.FIKLLLIFIVV....................
A0A084A612_9GAMM/1-99                ...........MAGDD.RKPIGRQGRQAKRQ-..APRRP.MR-RRR....DDDY.DDyddyddydeyeenE.YQDEY..D...D....DEdgydE....EYE........E.KRM..SRK...............-V...K.A.RPSR..K..K..RR.....W.LGL.LIKLFLVVAA-l...................
#=GC SS_cons                         ...........XXXXX.XXXXXXXXXXX--XX..XXXXX.XX-XXX....XXX-.--.............-.--XXX..X...X....XX....X....XXX........X.XXX..XXX...............XXXXXX.X.XXXX..X..X..XX.....X.XXX.THHHHHHHHHH....................
#=GC seq_cons                        ...........MuGsD.REPIGRKGK.s..+P..s+p+s.sRtRpR....-DDY.DD...............h......-...D.....-....D....t--........E.csh..PRK...............uK...t.u.+.PR..+..K..Rp.....W.LhL.LlKLhlVhsVl....................
//
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