#=GF ID   DUF6237
#=GF AC   PF19750.2
#=GF DE   Family of unknown function (DUF6237)
#=GF AU   Williams LS;0000-0001-5551-8526
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Fragoso S;0000-0001-7018-3891
#=GF SE   Manual
#=GF GA   25.00 25.00;
#=GF TC   34.10 33.70;
#=GF NC   23.80 21.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   25746634
#=GF RT   Biosynthesis of the anti-infective marformycins featuring
#=GF RT   pre-NRPS assembly line  N-formylation and O-methylation and
#=GF RT   post-assembly line C-hydroxylation chemistries.
#=GF RA   Liu J, Wang B, Li H, Xie Y, Li Q, Qin X, Zhang X, Ju J;
#=GF RL   Org Lett. 2015;17:1509-1512.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a member of a biosynthetic gene cluster
#=GF CC   (BGC). This BGC (BGC0001214) is described by MIBiG as an example
#=GF CC   of the following biosynthetic class, NRP (non-ribosomal
#=GF CC   peptide). It includes a member from the marformycin A
#=GF CC   biosynthetic gene cluster  from Streptomyces drozdowiczii [1].
#=GF SQ   6
#=GS A0A2P2GMP5_9ACTN/1-83   AC A0A2P2GMP5.1
#=GS A0A066YTY5_9ACTN/11-56  AC A0A066YTY5.1
#=GS A0A1C5C7P1_9ACTN/1-89   AC A0A1C5C7P1.1
#=GS A0A117PMF5_9ACTN/1-66   AC A0A117PMF5.1
#=GS A0A498AUX3_9ACTN/1-111  AC A0A498AUX3.1
#=GS A0A2G5II61_9ACTN/1-90   AC A0A2G5II61.1
A0A2P2GMP5_9ACTN/1-83              .....mt---------PQG...........W.DQATYR..........CGQCGA.ERTAATEAEHIKAIAAHRDAHTVWERLAPVERDGFVAVLREIFSMPELCQELIALAAAESQSET-r..
A0A066YTY5_9ACTN/11-56             ialtppa--------AEQA...........W.DTAEYT..........CARCWT.TVTASTEAEFVRLVVEHRDS---------------------------------------------cr.
A0A1C5C7P1_9ACTN/1-89              .......MTTEPATGSSSG...........W.DQAIYR..........CGRCGA.QSTVTTEEAYLQAVGVHTDAHAVWDRLNPMERDGFASILRTILSAPDLGFEFLALADRR--QH--tgd
A0A117PMF5_9ACTN/1-66              ....mtg----------QG...........W.DQAEFS..........CGRCGE.HITATTEEEYLTRVLAHRTAHDLLDA-----------------SSPELRARLLDLALAEVER---vlt
A0A498AUX3_9ACTN/1-111             .......MGGTDGAGGPGGavlpgagrpycWmSQAIAAavmpsagsspCAQCGSiEHTATTEDDYLKAVGTHRDAHAVWDRLTPIEREGFASILRTILSAPDLAVEFLALADR--QRS--gd.
A0A2G5II61_9ACTN/1-90              .......MTTEPDSPAACG...........W.DQATYR..........CGRCGA.EYTVTTEEAYLQAVGVHTDAHAVWDRLNPIERDGFASILRVILASADLGAEFLAIADRMKRLQG-g..
#=GC seq_cons                      ...............uspG...........W.DQApYp..........CGRCGu.chTATTE--YLpAVusHRDAHsVWDRLsPhER-GFsulLR.IhSuP-LshEhLALAst..ppp..s..
//