GenomeNet

Database: Pfam
Entry: PRP9_N
LinkDB: PRP9_N
Original site: PRP9_N 
#=GF ID   PRP9_N
#=GF AC   PF16958.8
#=GF DE   Pre-mRNA-splicing factor PRP9 N-terminus
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   PDB:4dgw
#=GF GA   27.00 27.00;
#=GF TC   27.00 27.70;
#=GF NC   26.90 26.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   22314233
#=GF RT   Structure and assembly of the SF3a splicing factor complex of U2
#=GF RT   snRNP.
#=GF RA   Lin PC, Xu RM;
#=GF RL   EMBO J. 2012;31:1579-1590.
#=GF DR   INTERPRO; IPR031590;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is the N-terminal domain of pre-mRNA-splicing factor PRP9
#=GF CC   [1].
#=GF SQ   73
#=GS A0A1Q2YII3_9ASCO/3-146   AC A0A1Q2YII3.1
#=GS G8ZTV2_TORDC/2-155       AC G8ZTV2.1
#=GS C4Y405_CLAL4/2-137       AC C4Y405.1
#=GS Q6C2A2_YARLI/2-144       AC Q6C2A2.1
#=GS A3LZB0_PICST/6-142       AC A3LZB0.2
#=GS A0A167D3V1_9ASCO/4-166   AC A0A167D3V1.1
#=GS G3B5U3_CANTC/3-134       AC G3B5U3.1
#=GS A0A1X7RB61_9SACH/2-146   AC A0A1X7RB61.1
#=GS A0A376BAD8_9ASCO/4-167   AC A0A376BAD8.1
#=GS A0A1E4TWP2_PACTA/3-129   AC A0A1E4TWP2.1
#=GS A0A1E4T2L3_9ASCO/3-138   AC A0A1E4T2L3.1
#=GS A0A512UN29_9ASCO/1-136   AC A0A512UN29.1
#=GS A0A1V2L0J7_CYBFA/36-146  AC A0A1V2L0J7.1
#=GS A0A1E3PEN1_9ASCO/1-139   AC A0A1E3PEN1.1
#=GS C5MGT4_CANTT/8-138       AC C5MGT4.1
#=GS W6MTM8_9ASCO/29-68       AC W6MTM8.1
#=GS C5DR22_ZYGRC/2-152       AC C5DR22.1
#=GS A0A1E3QJ40_9ASCO/3-139   AC A0A1E3QJ40.1
#=GS A0A1D8PNA1_CANAL/3-137   AC A0A1D8PNA1.1
#=GS A7TQD9_VANPO/2-151       AC A7TQD9.1
#=GS A0A1G4KK06_9SACH/2-155   AC A0A1G4KK06.1
#=GS A0A1S7H9I0_9SACH/2-152   AC A0A1S7H9I0.1
#=GS I2JWH6_DEKBR/1-86        AC I2JWH6.1
#=GS A5DJE8_PICGU/3-140       AC A5DJE8.2
#=GS G0WE55_NAUDC/5-162       AC G0WE55.2
#=GS G8B9Q3_CANPC/3-138       AC G8B9Q3.1
#=GS Q6FNA1_CANGA/1-159       AC Q6FNA1.1
#=GS A0A5E8B2Z4_9ASCO/4-149   AC A0A5E8B2Z4.1
#=GS A0A421J489_9ASCO/3-140   AC A0A421J489.1
#=GS A0A1E4SQ45_9ASCO/3-142   AC A0A1E4SQ45.1
#=GS Q6BPR8_DEBHA/2-138       AC Q6BPR8.2
#=GS K0KUL5_WICCF/1-142       AC K0KUL5.1
#=GS J7S3A2_KAZNA/1-148       AC J7S3A2.1
#=GS A0A7H9AZQ2_ZYGMR/2-153   AC A0A7H9AZQ2.1
#=GS G8BMP8_TETPH/2-154       AC G8BMP8.1
#=GS A0A1E5R097_9ASCO/2-171   AC A0A1E5R097.1
#=GS G8XZ63_PICSO/2-138       AC G8XZ63.1
#=GS A0A1A0HD69_9ASCO/1-136   AC A0A1A0HD69.1
#=GS C5DEG1_LACTC/2-145       AC C5DEG1.1
#=GS A0A448YS34_BRENA/3-52    AC A0A448YS34.1
#=GS C4R555_KOMPG/44-137      AC C4R555.1
#=GS A0A1G4IU42_9SACH/2-149   AC A0A1G4IU42.1
#=GS J8Q9Q6_SACAR/2-150       AC J8Q9Q6.1
#=GS G0VCY3_NAUCC/3-148       AC G0VCY3.1
#=GS W6MTM8_9ASCO/70-162      AC W6MTM8.1
#=GS G3ANP3_SPAPN/3-143       AC G3ANP3.1
#=GS A0A1D2VES1_9ASCO/9-161   AC A0A1D2VES1.1
#=GS J8TY71_SACK1/2-99        AC J8TY71.1
#=GS A0A2P7YME5_9ASCO/2-130   AC A0A2P7YME5.1
#=GS H2ARV0_KAZAF/2-144       AC H2ARV0.1
#=GS Q6CIR1_KLULA/7-154       AC Q6CIR1.1
#=GS G8Y250_PICSO/2-138       AC G8Y250.1
#=GS A0A1G4MCZ6_LACFM/2-149   AC A0A1G4MCZ6.1
#=GS A0A4P9ZA43_9ASCO/1-132   AC A0A4P9ZA43.1
#=GS M3HGC2_CANMX/3-136       AC M3HGC2.1
#=GS A0A2U9R431_PICKU/3-136   AC A0A2U9R431.1
#=GS A0A367YHB0_9ASCO/3-139   AC A0A367YHB0.1
#=GS Q757U7_ASHGO/2-157       AC Q757U7.2
#=GS A5E2D1_LODEL/3-158       AC A5E2D1.1
#=GS PRP9_YEAST/2-150         AC P19736.1
#=GS PRP9_YEAST/2-150         DR PDB; 6G90 T; 2-150;
#=GS PRP9_YEAST/2-150         DR PDB; 4DGW A; 2-150;
#=GS PRP9_YEAST/2-150         DR PDB; 5ZWO u; 2-150;
#=GS A0A1E3NDZ0_9ASCO/3-146   AC A0A1E3NDZ0.1
#=GS A0A448YS34_BRENA/43-137  AC A0A448YS34.1
#=GS A0A7H9HSM9_9SACH/2-154   AC A0A7H9HSM9.1
#=GS A0A1L0DM25_9ASCO/23-151  AC A0A1L0DM25.1
#=GS A0A1E4RT04_9ASCO/36-136  AC A0A1E4RT04.1
#=GS A0A0C7MMZ6_9SACH/2-153   AC A0A0C7MMZ6.1
#=GS A0A421JTQ0_9ASCO/3-143   AC A0A421JTQ0.1
#=GS G8JQN9_ERECY/2-157       AC G8JQN9.1
#=GS A0A1E3NV65_WICAA/1-147   AC A0A1E3NV65.1
#=GS A0A4P6XU23_9ASCO/1-136   AC A0A4P6XU23.1
#=GS A0A1E4RT04_9ASCO/3-42    AC A0A1E4RT04.1
#=GS A0A1S7HEQ3_9SACH/2-152   AC A0A1S7HEQ3.1
#=GS A0A2V1B0L7_9ASCO/2-135   AC A0A2V1B0L7.1
A0A1Q2YII3_9ASCO/3-146              ........t-SLEEKRQLLEDLELLDYAITKRIKVNPKIY------------.---......TPK....DANLDHNILF.PNKK.IAD.....--ASTILQKHEVKSFVQKYEAEKR.S.LV....N....L....L.....-....L.....D.....EE...T...SF.HDTNilkr......................payekGDFTE..FFKMCEDVLETSQSv...............gSSSVGSLCCK.......dYEIYDLFSC----nany...............................
G8ZTV2_TORDC/2-155                  ........n-TLESRRSHLEDLEVIEQSIASRFERNPGLYYGYLQKRALIDD.-IP......LSSs..iTNAYNANRIY.KAKR.SKR.....NRKQFVLQQHEIDLFLQESMRKLR.D.LG....S....L....K.....G....P.....V.....NT...H...SL.RDEE...............................ATFEI..FKQNLEEIKDKYKDl..............gsDSLFSDVNEE........ISKHAMFSALTT-d..................................
C4Y405_CLAL4/2-137                  .......nl--AETQRQTLEEIDILEVETAQRFRRNPEL-----GRAA----.---......---....-QIRQTDSVL.ES-R.RKR.....PHKETLLQQHELKYFSNQYERDCSrA.IK....N....F....E.....Sp.elL.....S.....QI...E...SL.RDPN...............................LKFES..INRALTELESRFKS.................-VPIQSATPS........RSAFLMYSSA---ped................................
Q6C2A2_YARLI/2-144                  ........t-----TRAALEEMEVIEAGIAERLAFNPLILPPSQ----ALTP.NSP......LQP....RLQKLKNVPF.TRQVgTPT.....THRQTVLRQHEIATMLDTYQKLAR.R.LK....A....EldapR.....G....K.....S.....GS...R...NL.SSKEl.............................kGVMTD..FYAKIDKIKQTLVP.................----------........-------------geqaqdmyanytlkrpa..................
A3LZB0_PICST/6-142                  ......rnv-----ARSILEELDVIELESSRRFRKDPLLYPQNE--------.---......---....--NKEKLQIV.---R.TKR.....PQKEVKLQQHELAVFQQKYKKHCN.S.LR....N....H....T.....A....-.....-.....ND...S...DI.IQSIlgtl.......................ddskATFSN..FDSALAQIQEKHNK................tNNGEIEVAES.......iRNMYTMFSSI---lfs................................
A0A167D3V1_9ASCO/4-166              ........e-ILEIERSALEELERIEQAVTDRIVHNPWILPDTL----Q---.---......LS-....-----T-SSS.LNGK.RKR.....PVRETTLSQLEVAKFLERYQEQCK.Y.MN....S....V....I.....S....G.....V.....KR...R...RQ.KKGDevdatdggalvladqhikevkalgefsgasqQLLDQ..YSKEVSSI------.................----------........-------------kefyrkypnqdvddlaatyamartlkkr.......
G3B5U3_CANTC/3-134                  ........q-FIELQRSRLEELDIIRQATSKRFRKNPSL-------------.---......IPT....-NIRERDDIL.SGNK.-ER.....PFKETMLQKHELKLFQDKYNSNTK.A.LN....S....L....D.....K....D.....L.....VEtslN...KI.NDPE...............................FKFEY..FDSLLNGLQEKEDS.................---SLFNEDL........KSLYSIYSSS---plq................................
A0A1X7RB61_9SACH/2-146              .......tq--LDKRLGLCEDLEVIEDAISRRLERNPELYYSSLDKLQSLCRtKVH......LPS....SKQIVGNKVY.KTSK.PHR.....SSKQVQAQLHEIKIFLDDYYRKLS.E.LN....K....I....S.....K....L.....-.....PE...N...ES.S-TE...............................DKLNQ..LKLQIDQIQSNDK-.................--LVSKLDTK........IEEYAMISK----ptt................................
A0A376BAD8_9ASCO/4-167              .......dq--LEKQRLKYEELEVIEKNITERIQRNPQVFYANYQEYLKIAG.GNNirlkslIA-....KENISSNRIY.KWKR.RIR.....KRKQTLIQQHEINDFLKRVLQLCN.E.IE....D....T....A.....N....E.....T.....DL...K...KE.VQKNysie......................entdeLDLDK..FDLLLKSINSTYDK.................HDPSDNDDDF........NREYKMFPTN---hfn................................
A0A1E4TWP2_PACTA/3-129              .......rl--AENERSIFEELERIEVEISRRIKRNPEVYQSSGG-------.---......---....-----NHNIL.GG--.KKR.....SLRETLLQQHECKLFLDQYSNQCR.T.LK....R....L....M.....G....-.....-.....SD...Q...DM.KNAK...............................IDLNE..FESAYDEIKQFHYK.................-YPNNPVDDL........SNIYSMFSSNV--nt.................................
A0A1E4T2L3_9ASCO/3-138              ........t-VLEEERSLLEELEKIEYAVTKRIKRNASIYKPTT--------.---......---....-LSKDHN-IL.E--D.GKK.....PLAQTLLQQHEIKKLIDKYQTQSS.T.LL....T....F....Lq...nD....K.....D.....EI...S...QL.KEEN..............................aDSFKV..FEKLYKETTANHQK.................-TLLLGISKS.......eEDIYDMFSCNVE-kd.................................
A0A512UN29_9ASCO/1-136              .......ms--LETQRQLLEELNVLEKACTQRFRRNPAL-----RSAAKVR-.---......---....----QPDDVL.ES-K.AKR.....PHLETLSQQHELEYFSNQYQADAD.R.CR....G....A....Fvh.etL....A.....K.....EI...S...AM.SDPD...............................MTFKH..IMATIQNIDAKYRH.................-VSPGSASSM........IDSFAMYSSA---pre................................
A0A1V2L0J7_CYBFA/36-146             .....nlll-------------------------------------------.---......---....----------.--KG.KKR.....SFREILLQQHEMERFIDNYKRQKV.S.LD....T....V....R.....N....S.....T.....GQ...DdlkEL.QDKT...............................FELQK..FDQLFNKLKQKDSDgvvnglqhiyslksssgI--------NilsevgadIDLSSMFS-----gee................................
A0A1E3PEN1_9ASCO/1-139              .......ms--FEHQRSFCEELERIEVALSQRIARNPALLPSHI--------.---......-PL....--TVNSPLAG.RVAK.KRK.....SDRETIFGQHEVAKLLDRYRSICG.D.ML....D....I....S.....A....D.....-.....--...D...KL.KEKElaaldg..................tkaptldAIFAT..YDAKVDDLRAYH--.................----------........-------------rkyaiesvnsladayelk.................
C5MGT4_CANTT/8-138                  ........n-FIETQRSNIEELDIIEDSVSKKLLKNPFILPSHL--------.---......QPK....----QNFLIS.KINK.PKS.....TKRLTLQQQYELKYFNDRYNQIIK.D.LN....H....C....L.....N....S.....-.....-E...K...EL.FDKAl............................pePSFEK..FDELINNIPENEEM.................------VTDP........RVLYSSYSSLD--kek................................
W6MTM8_9ASCO/29-68                  ........t-TLEETRSALEELESIEAGIAERLQYNPDIHHSQND-------.---......---....----------.----.---.....------------------------.-.--....-....-....-.....-....-.....-.....--...-...--.----...............................-----..--------------.................----------........-------------hgvl...............................
C5DR22_ZYGRC/2-152                  ........t-TLETRRQLLEGLEIIEDAISQRFGRNPELYYSNITKQVLIDG.GIE......LPS....TTAMAVNRIY.KSKR.TKR.....SRKQLVTQQHEINLFLSQALDKQK.E.LS....G....V....N.....G....T.....V.....DV...E...DY.RDEE...............................INFDK..FREAVDQINSKYED................qEGLALDINEN........IVNHEMFSATFS-k..................................
A0A1E3QJ40_9ASCO/3-139              ........t-TIETVRSAIEEVEEIEIAILSRLQRNPKIYA-----------.---......-PE....---SRHDSVL.LRNT.KKR.....SYKETLTQQHEVSLLLSQHAKRCG.V.IK....E....L....L.....Q....D.....T.....RS...S...ML.A-VEiatf.......................kdssNDLKM..FDSCIANIKLHHER.................-YPNLQVEDL........AHLYSMGSS----gii................................
A0A1D8PNA1_CANAL/3-137              ........n-FIEVQRSNIQEIGIIEDSLSRRLLRNPYILPSNLQPRPNI--.---......---....-------LVS.KVTK.PNS.....TKRISILQQYELGYFKDRYNQIIK.G.LN....H....C....L.....T....D.....E.....KE...S...FS.RTLElit.........................epgDGFEK..FDEMINGISSNDNI.................------VEDP........RKLYSSFSSLNK-e..................................
A7TQD9_VANPO/2-151                  ........s-YIENVRSLLEDIEVIEDAISKRFQRNPEVYYYYSQQLNDINGgGEEt...ktV--....VSNRSSNRIY.KSRK.HKR.....DRKQVILQQYETNEFIKDIRSKLN.E.IR....E....I....N.....V....T.....K.....ES...N...GI.K---...............................--LDR..YVELMGSIDTKYEDs..............vsDNQQLPINKT........IFQYSMFTSSNS-k..................................
A0A1G4KK06_9SACH/2-155              .......np--IEAKRIALEELEVIEKAIADRIGRNPALFYDYFDELKAIEG.EKAi....dVPV...tKAQATQNRIW.KISK.PRR.....SKKQVALQQHEIKSFLDRYNETSH.F.ID....G....T....T.....G....-.....E.....DV...S...DF.EDPH...............................GTFAA..LEGSIETLKSRFQG................tE--NSDSEQSt.....ilSRQYSMFSASTE-e..................................
A0A1S7H9I0_9SACH/2-152              ........a-TLEKRRELLEDLEIIEDAISHRFLRNPELYYSNAIKEALLDG.TMQ......LPS....TSNMAANRIY.KNKK.AKR.....SRKQIVTQQHEIDLFLSQMLAKQK.E.LN....S....L....K.....G....P.....V.....IT...E...DY.EDNE...............................NNFKQ..LKEKLAEINGKYES................aEDSPLDVNEK........IAQYRMFSASG--es.................................
I2JWH6_DEKBR/1-86                   ........m-------------------------------------------.---......---....----------.----.---.....------IQKHEIKSFINRYKSQLE.K.LA....I....L....T.....S....K.....E.....NE...Q...EL.KHELrssk.......................qgnlNDLDK..FTNNLQEILDTPED.................-XAKNRNSDE........LXLYDMYSSNT--kl.................................
A5DJE8_PICGU/3-140                  ........g-YIELQRSLLEESDIIEDAIAQRARRNVDVVPAEV--------.---......RPE....----EVKDLF.STR-.-KR.....PLKELVQQQHEVSYFLDKCKKQKK.A.FI....D....A....Rtd.paV....D.....E.....EL...K...RI.EDTS...............................TDFVE..FDKMLEKIVKHYKI.................QQKEPSAPQD.......iAELYKMYSSA---ppt................................
G0WE55_NAUDC/5-162                  ........d--LEKRRSLLEDLEIIENAISTRFQRNPELYYSNLKKVSELFP.SKQv...eeLPT....HSIMTNNKIY.KTKK.LKR.....NRKQIALQQHEISLFIKDFFSKQK.E.LE....T....L....T.....R....E.....A.....NF...K...AK.KNKEe............................ilLPVEE..FKDILSEINEADGNe..............ngNRRELEINDK........INKYSMFSNSLN-k..................................
G8B9Q3_CANPC/3-138                  ........n-SLEKQRSALESLDAIEVALSRRFLRNPDL-------------.---......LPK....TLRPKHGNIL.TEKR.RVH.....TKRLFRLQQHELKQLSDEYNLLLK.Q.AS....AsfdnV....A....pI....K.....Q.....DL...Q...NL.KEED...............................DSLVK..FDNLIAPLINDPDE.................---GRNVQDT........QSKYSLFGSADP-k..................................
Q6FNA1_CANGA/1-159                  .......me--LDTVRSLLEDIEVIEDAISSRFQRNPELYYDYRIHLEGIRD.D--......IPKl.glDDDRMVNKIY.KARK.HKR.....TLKQKRTQQYEINTFLDDIFKKNK.Y.IL....K....V....R.....N....Q.....L.....KS...D...GL.KYKDs.............................eCKFEL..LKKLLGDEPTEDEDedds........isksnSSRLLDIDET........INRYNM-------nlgn...............................
A0A5E8B2Z4_9ASCO/4-149              ........s-LLEAQRSSLEELDRIEQAISERITRNPAILPDNA----RL--.---......---....-----SASSE.LHGR.RKR.....PFKETVLQEQEVGRFVKRYREQCE.F.LE....K....S....F.....L....E.....T.....GP...N...AVaRKKElaelat...................tddarvSLLDN..FYRQANAVKEYHRR.................-YPNQEVEDL........HAQYQM-------givslrkq...........................
A0A421J489_9ASCO/3-140              ........g-YIELQRSLLEESDIIEDAIAQRVRRNVDVVPAEV--------.---......RP-....---QEVKDLF.STR-.-KR.....PLKELVQQQHEVSYFLDKCKRQKQ.A.FL....D....A....K.....N....Dpa.vdE.....EL...K...RL.EDSS...............................GDFVE..FDKMLDKIVKHYEI.................QQKEPSAPQD.......iAGLYRMYSSA---pat................................
A0A1E4SQ45_9ASCO/3-142              ........p-YIESQRSKLEEIDAIESNIAKRFKRNPYLL------------.---......-PE....-SRRPSPDILtATRA.NKR.....SQKESVLQQHEIKRFVEKYSTLRA.N.VL....G....F....K.....E....K.....N.....--...-...EL.FQEEltri.......................sdpkLTFSA..FDEALELIKQKHEQ.................DSAS------........-------------gvlllaaedinkvyapysga...............
Q6BPR8_DEBHA/2-138                  ........s-LLESQRSILEEIDVLEQSISQRVQRNPSLLPSSQ--------.---......KPS....-------DVT.ISSS.KKR.....PLKEELLQQHELKFLKNKYRRHCS.T.VL....G....N....K.....D....T.....-.....KR...N...HF.EEESnkl........................kdpaYEFKL..FDSMLNDIKQHHEL.................QTETNQAEDI........SKIYRMYSSA---pr.................................
K0KUL5_WICCF/1-142                  .......ms--LEQERSALEELHFLEQEISSRIQRNPELYPKFNEDLN----.---......---....-----SN---.LNNK.KKR.....SFREVLLQQHEINRFIDQYKKQKS.N.LQ....Q....S....LndaesR....N.....Q.....EI...Q...SL.KDPT...............................LELIK..FDEIYQNLKNQNDS.................-NIVKPLNSIygl.ktskINILSEFS-----sdle...............................
J7S3A2_KAZNA/1-148                  .......mg--LDERVSLIRQLEILEDAIAARFQRNPALYYNSVPMLKKLTM.QAEp...kvCPP....QDHVTKNKVY.RVEK.SAR.....KVKQVATQQHEIKLFLQDRTDILN.K.LS....R....A....Q.....E....S.....G.....PG...E...SQ.Y---...............................KNLDE..FKTAINGLTESNIP.................--KRSGLQSE........KDQYAMFSSSIE-k..................................
A0A7H9AZQ2_ZYGMR/2-153              ........e-VLESRRALLEDLEIIEDAIASRFCRNPALYYSYLEKRAAISQeTLD......KPS....ISAMQANRVY.KSKR.MKR.....SRKQLVLQQHEINLFLREAFQKLR.K.LG....S....L....E.....G....P.....L.....DM...G...GL.LDEK...............................SDFEA..FINKLGEVDGERRN................sEDSTLEVNEK........ISQYAMFSASSS-k..................................
G8BMP8_TETPH/2-154                  ........s-NIEERRSLLEDLEVIESSITKRFQRNPELYYKYQEGLKKVVDpDID......LPS....KTVRNTNKIY.KTRK.HKR.....KRKQILLQQYEINEFLDDYRRKEK.Q.L-....-....M....K.....Q....K.....L.....DI...S...EF.RDKG...............................ADFVK..FEELLESINNEYNN.................QNEETPTNLKll....dkKDKYAMFSSSI--ni.................................
A0A1E5R097_9ASCO/2-171              .......nd--IEQERLNCEKLDTIALNITRRFERNPAVFYRNQAEYYKTGF.PTT......LASsfdnSELARKNSLL.KVEK.PLR.....SKKQILAQQHEINRFCKIFKDTKL.H.MQ....E....G....K....gF....T.....R.....DL...V...QV.AKGElgn.........................qdeLDFLR..FDSIVNNIIDEHESrt.............gnSEKTHFIKSTka...dslDDEFSMFP-----hqlqi..............................
G8XZ63_PICSO/2-138                  ........p-FIELQRSYLEELDAIEVAISKRLERNPNL-------------.---......IGR....--HFTDNEGE.IIHT.KKR.....PYEEEILQKHELGYLIEKYKSQNQ.KvLA....N....V....R.....Y....R.....KellsqEA...E...EL.RDGK...............................LDMEN..FDMKLAEIKRDNES.................EER-DLVDDV........NQIFSMYSSID--pe.................................
A0A1A0HD69_9ASCO/1-136              .......ms--LEAQRQLLEELNVLEAAAAQRFRKNPAL----RAAA-----.---......---....-RILLADEVL.ES-K.PKR.....PHLENIMHQHELAFFHSQYAMDGE.R.CT....N....V....Fag.daL....A.....S.....EI...S...AF.KDPD...............................LKFQH..ILATIRNIDDKYHG.................-AAPGSAGSV........ADSYAMYLS----apka...............................
C5DEG1_LACTC/2-145                  ........k-TYEDARATLEELELIENAVTSRLRRNPEIFYRNIDEVDLVEH.SGRf...dhIPS....-SQKSANKVY.TVKK.SRR.....SRKQILAQEHEIKSFLSQYLKDCQ.S.LG....R....V....-.....-....E.....F.....DM...S...EY.RVDN...............................GSVNK..LLEHIERIKEIHPK.................------DDEF........GDQYAMFSSSTP-s..................................
A0A448YS34_BRENA/3-52               ........t-LLEEERRTLQELDLIESSISKRIKRNPDIYQ-----------.---......---....----------.----.---.....------------------------.-.--....-....-....-.....-....-.....-.....--...-...--.----...............................-----..--------------.................----------........-------------ppkdhgilgrrrslpkge.................
C4R555_KOMPG/44-137                 .......gv-------------------------------------------.---......---....----------.----.-KR.....PLKQTLLQQHEIKHFLDQYSKKSQ.Q.IN....Q....E....V.....I....K.....D.....GE...K...LF.QEIQeik........................ldlsGSFKL..FGQKIEQLKNNHKM.................-HPNQPLDEL........SQLYSMFSSQF--en.................................
A0A1G4IU42_9SACH/2-149              .......as--YDKARDALDELEQIENAISSRFKRNPELFYRTTDSWKAMKM.PWD......FPSi..sEADKAANKVF.SVSK.PRR.....NRKQVSAQEHEINMFLEEYQKNCS.L.LT....T....L....K.....-....F.....E.....DS...E...KY.KIPD...............................GSVDK..LLRDIDDIEKRFAN.................RSLE---DGL........VDEYGMFSSSTA-e..................................
J8Q9Q6_SACAR/2-150                  ........n-YLETKRSLLEDMEIIENAIAERIQRNPELYYHYIQKASKVFS.DVE......LPR....SSLISENKVY.KLKK.VRR.....TRKQVILQQHEIDLLLRDYREKQE.L.FN....Q....S....-.....-....-.....S.....EL...E...RG.QEDD...............................EDLQS..FEKKLHELEEELKSd...............qDNFQLDINLK........RSKYALFSSSA--dp.................................
G0VCY3_NAUCC/3-148                  ........p-LLEKKRNLLEDLEVIEDAIAKRFQRNPELYYDNITKLSILTNlSID......TPA....ESNKSNNKIY.KRKK.LKR.....SRKQFVLQQQEINIFLKDFEERRR.V.LL....D....L....-.....-....-.....-.....GK...E...TV.KDDN...............................ITLET..FKTMIQDINAKKSS.................-SEVLPINQK........ITRYAMFSASIS-e..................................
W6MTM8_9ASCO/70-162                 .......gg-------------------------------------------.---......---....----------.----.-KR.....TIGQTLLQQHEVKLFLDEYSKQCD.A.VK....K....N....L.....Et..fS.....S.....DF...E...SF.DDKE...............................LNFNK..FDGLLSNIKDYYAK.................YPEA------........-------------pqdssnifamygigvddgkrrk.............
G3ANP3_SPAPN/3-143                  ........g-FIESQRAALEELDVIEEAISSRLGRDPHL-------------.---......LPP....-SLRPKKDII.SKRK.PKKt...sTLRLSLLQQSELRFFIEKYHRTHS.S.LE....F....C....-.....-....L.....A.....NE...K...LV.LQKQlanv.......................tegpKQFAK..FDQMISEISNKESD.................HPSGAIAEDP........RNLYSSFSSITR-d..................................
A0A1D2VES1_9ASCO/9-161              ........n-YLEEQRNALEELDRIQLEISNRIQRNPAVYVGST---QNIDH.G--......VL-....----------.-NQN.NKR.....PVKEVLLQQHEINSFIKRYKKNSL.Y.LS....N....Fy..lK.....N....S.....N.....DF...P...HH.IDSE...............................YEIDK..LNHQISFISDPNYS................fENFDL-----........-------------lyrniqknylfnthsqdgnhnlsllfsmgssnlsk
J8TY71_SACK1/2-99                   ........n-VLETRRSLLEDLEIIENAIAIRIQRNPELYYHYIQESCKVFP.DVK......LPK....PSLIAENKIY.KLKK.VKR.....NRKQVILQQHEIDLFLRDYHEKQK.A.FN....E....S....N.....-....-.....-.....--...-...--.----...............................-----..--------------.................----------........-------------nl.................................
A0A2P7YME5_9ASCO/2-130              ........s-LLEAQRQLLEENDALEVAVAQRFRKNPGLAGSC-----RVDQ.SHK......L--....----------.-ATK.KKR.....SHKETLLEEHELKFFEETFKSNSK.R.LK....E....Q....L.....S....SktdlvK.....EI...K...AF.KDPD...............................FRFHL..FLDAMKDLDSKRGD.................KQTS------........-------------aktvlssilpy........................
H2ARV0_KAZAF/2-144                  ........a-NLEEKRDLCEDLEVIEDAIAKRLQRNPELYYNYLEKLSSFEKhSLE......VPS....SIDIKNNRVY.KSKK.AKR.....SKKQIVAQQHEIRLFIEDYTNKQK.G.LN....M....L....M.....K....R.....K.....DT...T...QI.S---...............................SDIGD..FITSITENKSHVKS.................-----SLKDK........IDYYSMFSASTT-q..................................
Q6CIR1_KLULA/7-154                  ........l-CFEERRKILEELEVIEDAISSRLRRNPEIFYRFNEALHNLGV.EAW.....aVPK....-LDVSANRIY.RSKK.SKR.....SRKQIKAQEYEIALFLGRYRRLLK.S.LQ....K....H....K....lS....E.....E.....HL...E...YF.RDTN...............................ASFEQ..FETVTTEVLEGQVN.................---SRSLVEV........KSDYEMFSG----pqaa...............................
G8Y250_PICSO/2-138                  ........p-FIELQRSYLEELDAIEVAISKRLERNPNL-------------.---......IGK....--HFTDNDGE.RIHT.KKR.....PYEEEILQKHELGHLIEKYKSQNQ.KvLA....N....I....R.....Q....R.....K.....EL...L...LQ.EAEElr..........................dgtLDMEI..FDMKLAEIKRDNET.................EER-DLVDDV........NQIFSMYSSID--pe.................................
A0A1G4MCZ6_LACFM/2-149              .......ts--CEDQRASLERLEVIEDAISSRIRRNPEIYYRLYQKLKQINF.KEPp...ehIAS....-SKIQENKIF.NVKK.SRR.....SKKQIAFQQHEINQFLEEYERQVS.S.LM....Q....T....-.....-....E.....I.....DI...E...SL.RDDK...............................LNFEA..FDKEIELIKDIPEN.................---NLEATAS........LNEYALFSSSTS-tq.................................
A0A4P9ZA43_9ASCO/1-132              .........--MEAQRQLLEELDVLECAIAQRFKRNPELIAAV--GLQEF--.---......---....------DPIF.D-SV.PKR.....PHKETLIQQHEIKFFVEQHAANRA.R.VK....R....G....F.....EsgaiQ.....A.....EA...Q...RL.KDPK...............................KSYDA..LLQAVAELQADEQG.................-NQGLRAVSL........KSQYAL-------ylcap..............................
M3HGC2_CANMX/3-136                  ........n-FIEQQRSSIEDCDILEEAVSNRFLKNPHSLPKFLRPTKD---.---......---....---ILLS---.KISK.PKT.....TRKISLLEQYELKYFLDQYNQTIK.N.LN....H....C....I.....-....-.....D.....HE...Q...SL.LDKDles........................ltesNSFTK..FDELINSIPSNNEI.................------VKDP........RFLYSSFSSLNK-e..................................
A0A2U9R431_PICKU/3-136              .......te--LEHKRQLIEDLELIEHAVIKRIRHNPQIYKPRD---TRLNH.---......---....DVLIE-----.---N.PKI.....DESITLLQQHEVQKLLDKYEAERK.V.LL....E....L....L.....N....D.....E.....DS...-...-I.LHDLkv..........................lkdPQFENgiFTRFVEECLSIEPS.................---TTEI-KD........HEIYDMFSSNS--ay.................................
A0A367YHB0_9ASCO/3-139              ......nfp---EIQRANIEELDVIEEALSKKLLKNPYILPAHLQ-------.---......-PK....----HNILIS.KINK.PKS.....TKRLSLQQQYELKYLNDQYALILK.D.LN....H....C....L....sS....E.....K.....DL...F...EK.GLPD...............................ASLEK..FDELINSIQESDEI.................------VRDP........RSLYASYSSLD--kekyphdst..........................
Q757U7_ASHGO/2-157                  ........s-SLEEKRAILEELEVIEGAISARIERNPEIYYSYLKELQLVNP.DEKvl..dnIS-....KDDINSNRIY.VNKK.ARR.....SRKQLILQQHEIARFLQRYWKQVK.R.LN....A....F....K.....-....S.....D.....DI...E...SL.RDPN...............................MNFET..FEADIKELQERQAEga.............dsESAISSLERK........RREYSMFSASS--ga.................................
A5E2D1_LODEL/3-158                  ........g-IIEVQRALLEESNALEEGISRRFQRNPKLLPKNL--------.---......IPKh..gDLLIDSNQSQ.KRKT.KKRnnrnySKRLVLLQQQELRLFLDRYKDILK.S.TS....R....I....N.....-....S.....G.....GK...Q...NL.GQVElgl........................ltekDSFDK..FDALLAKVHKPQAV.................DEEYGQDNIMal....npREAYSSFYTNDP-s..................................
PRP9_YEAST/2-150                    ........n-LLETRRSLLEEMEIIENAIAERIQRNPELYYHYIQESSKVFP.DTK......LPR....SSLIAENKIY.KFKK.VKR.....KRKQIILQQHEINIFLRDYQEKQQ.T.FN....K....I....N.....R....P.....-.....--...E...ET.QEDD...............................KDLPN..FERKLQQLEKELKNe...............dENFELDINSK........KDKYALFSSSS--dp.................................
#=GR PRP9_YEAST/2-150         SS    ........--HHHHHHHHHHHHHHHHHHHHHHHHH-THHHHHHHHHHHTTST.T--......---....HHHHHHTBSS.S-B-.---.....-HHHHHHHHHHHHHHHHHHHHHHH.H.HH....H....H....-.....-....-.....-.....--...-...--.----...............................-----..-HHHHHHHHHHTTSS...............---------SH........HHHHHHTSTT---SS.................................
A0A1E3NDZ0_9ASCO/3-146              ........t-SLEEKRQLLEDLELLDYAITKRIKVNPKIY---TPKDAKLDH.RIL......IPN....------KKIM.DA--.---.....---SVVLQKHEIKSFVQKYEAEKR.S.LV....N....L....L.....-....L.....D.....EE...S...SF.HDKNilkr......................peyekGDFAE..LFKMCEDISETSPSv..............kpHSTGSSSCKD........YEIYDMFSCN---any................................
A0A448YS34_BRENA/43-137             grrrslpkg-------------------------------------------.---......---....----------.----.---.....---ETLLQQYEIKQFIERYKSQYD.R.LS....E....L....M.....D....H.....E.....SI...A...LD.--GElkve.......................gndeDTFDK..FHELYTRSLAESRQ.................-QAIHVGVKD........ADIYDMFSSNE--ny.................................
A0A7H9HSM9_9SACH/2-154              ........e-TLESRRAQLEDLEIIEESISSRFERNPGIFYSYLENKASIDN.EP-......LNQy..iQNASKANRIY.KRNR.LRR.....NRKQIVVQQNEINIFLEESLRRLK.S.LS....D....L....T.....G....P.....V.....NI...R...SL.KDSD...............................ATFET..FRHNLDEIKEKFKEe...............mTTPRFQLRDK........RFDYAMFSAST--ar.................................
A0A1L0DM25_9ASCO/23-151             .......ms--LEAQRQLLEEIEVLEAACSQRFRKNPTL-ASYA----KISN.---......---....-----TDEVL.-EPS.RKR.....PHKETLLQQHELQFFAQQLQRDCN.R.AQanfkT....T....K.....L....H.....D.....EV...Q...RL.TDVK...............................MKFDQ..FEIQLEMLKETRGQ.................----------........-------------avwnaeelmdvfrly....................
A0A1E4RT04_9ASCO/36-136             .....sdts-------------------------------------------.---......---....----------.--SQ.SQR.....PSKETLLQKHELRFFFDKYKKQCS.LfLE....N....Y....E.....N....R.....K.....DIf.sN...EL.KSLNd............................psRDFQQ..FDNLLKFVNSRHEVg...............dTDEIEPAEDT........IRLYSMYSSAL--pd.................................
A0A0C7MMZ6_9SACH/2-153              .......va--YENARQNLEELELIENAISARFKRNPELFYRNVDQWKAMSL.EWE......HPDe..pQQSRSENKIY.MTKK.PKR.....SRKQIVAQEHEIALFLDAYRKNCD.E.LL....N....L....E.....-....F.....E.....DA...R...KY.QVSD...............................GSIDV..LLREIEAIGDGSDG.................-SKDHNDNGDy......sADIYAMFSNSTS-s..................................
A0A421JTQ0_9ASCO/3-143              ........g-FIESQRVALEELDVIEEAISQRLSRDPHL-------------.---......LPK....-SLRPKNDII.SKRK.SKKs...sTLRLSLLQQSELRVFIDKYHRAHS.S.LE....F....C....L.....-....-.....A.....NE...K...HV.LVKQlsni.......................aegpKQFTK..FDQLIRSISHKETD.................DRDGATAENP........RALYSCFSSITS-d..................................
G8JQN9_ERECY/2-157                  ........s-LLEEKRAILEELELIEDAISDRIARNPEVFYSYIHELSIVNS.DEKvl..snIPN....-VDITANRVY.MIKK.SKR.....SRKQILLQQHEISKFLSYYLKNVK.K.LN....G....Y....K.....N....-.....D.....NV...D...EF.KDHN...............................QNFEL..FRDQIQRIKEKYAEes.............nsEAFDASLEAR........KYQYTMFSNSNH-q..................................
A0A1E3NV65_WICAA/1-147              .......ms--IELERNTLEELHTIEKAITDRIQRNPELYDGFL--------.---......---....---EDNNRVL.-NKK.KKR.....SFREVLLQQHEISFFLKQYKKQKT.F.LE....E....S....W.....N....D.....A.....SR...N...EV.LKTIdd...........................ptYELIK..FDELYQSIKSQNDE.................----TVVKNL........GSIYAMKSSN---snilseigsgidlnlmfs.................
A0A4P6XU23_9ASCO/1-136              .......ms--METQRQLLEELNALEKASAQRFRRNPAL-----RAAAGV--.---......---....---RLADEVL.E-LK.PKR.....PHRETLSQQHELAYFRNQYELDAE.R.CR....K....TfsdnS.....L....A.....T.....QI...A...EL.KDPE...............................MSFKH..ILSIIQDIDKTHYG.................-VSAGSASST........FESFSMYL-----sapke..............................
A0A1E4RT04_9ASCO/3-42               ........r-FIEPQRFLLEEIDAIEQAVATRLRRYPHLLPNSDT-------.---......---....----------.----.---.....------------------------.-.--....-....-....-.....-....-.....-.....--...-...--.----...............................-----..--------------.................----------........-------------ssqs...............................
A0A1S7HEQ3_9SACH/2-152              ........a-TLEKRRELLEDLEIIEDAISHRFARNPELYYSNVIKEAFLDA.TMQ......LPS....TSNMAANRIY.KNKK.AKR.....SRKQIVTQQHEIDLFLSQMLAKQK.E.LN....S....L....K.....G....P.....V.....NT...E...DY.EDNE...............................NNFNH..LKEKLAEINSKYET................aGDLQLDVNEK........IAQYCTFSASG--es.................................
A0A2V1B0L7_9ASCO/2-135              ........s-LIEAQRQLLEENDALEVSVARRFRKNPVLASK-----CSVDQ.SH-......---....---------Q.LSTK.KKR.....SHKEMLLSEHELKFFEDTYKQNNS.R.LR....E....Q....L.....K....SksdllK.....DI...Q...AF.KDPD...............................MKFYS..FLDAMKDLNDKRPD.................K---------........-------------lesaknalaftlpyssvpa................
#=GC SS_cons                        ........--HHHHHHHHHHHHHHHHHHHHHHHHH-THHHHHHHHHHHTTST.T--......---....HHHHHHTBSS.S-B-.---.....-HHHHHHHHHHHHHHHHHHHHHHH.H.HH....H....H....-.....-....-.....-.....--...-...--.----...............................-----..-HHHHHHHHHHTTSS...............---------SH........HHHHHHTSTT---SS.................................
#=GC seq_cons                       ........s..lEppRshLEEL-lIEpAIopRhpRNPplh.t.....................s..........tsplh.p.p+..KR.....spKphlLQQHElphFlccYppppp.p.Lp....p....h....h.....t....p.....t.....ph...p...ph.pctp...............................hshpp..Fcphlpplpppppp.......................hpp.........hp.YsMaSu....s..................................
//
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