#=GF ID   PTP3_beta-sheet
#=GF AC   PF29840.1
#=GF DE   Polar tube protein 3 beta-sheet domain
#=GF AU   Morveli N;0000-0003-2496-881X
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   TED:Q8MTP3_TED05
#=GF GA   27.00 27.00;
#=GF TC   28.90 28.90;
#=GF NC   26.90 23.90;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 8 -Z 90746521 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12076771
#=GF RT   The microsporidian polar tube: evidence for a third polar tube
#=GF RT   protein (PTP3) in Encephalitozoon cuniculi.
#=GF RA   Peuvel I., Peyret P., Metenier G., Vivares C.P., Delbac F.;
#=GF RL   Mol. Biochem. Parasitol. 122:69-80(2002).
#=GF RN   [2]
#=GF RM   16691553
#=GF RT   Proteomic analysis of the eukaryotic parasite Encephalitozoon
#=GF RT   cuniculi (microsporidia): a reference map for proteins expressed
#=GF RT   in late sporogonial stages.
#=GF RA   Brosson D, Kuhn L, Delbac F, Garin J, Vivares CP, Texier C;
#=GF RL   Proteomics 2006;6:3625-3635.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents a beta-sheet domain found in polar tube
#=GF CC   proteins from microsporidia. The protein is involved in
#=GF CC   sporoblast-to-spore polar tube biogenesis and plays a role in
#=GF CC   controlling polar tube extrusion in response to ionic stimuli
#=GF CC   [1]. The protein is localised to the spore polar tube and is
#=GF CC   highly expressed during polar tube formation [1,2]. The specific
#=GF CC   function of this middle domain remains to be determined.
#=GF SQ   18
#=GS A0A4Q9LUX4_9MICR/1066-1160  AC A0A4Q9LUX4.1
#=GS A0A059F218_9MICR/836-921    AC A0A059F218.1
#=GS A0A437ANB8_9MICR/1000-1066  AC A0A437ANB8.1
#=GS R0KXX2_NOSB1/893-974        AC R0KXX2.1
#=GS R0KX08_NOSB1/893-974        AC R0KX08.1
#=GS A0A4Q9LJH3_9MICR/1066-1160  AC A0A4Q9LJH3.1
#=GS C4V6P2_VAIC1/1013-1094      AC C4V6P2.1
#=GS A0A0F9ZHF1_9MICR/1013-1094  AC A0A0F9ZHF1.1
#=GS A0A0R0M047_9MICR/955-1044   AC A0A0R0M047.1
#=GS A0A0B2UIV2_9MICR/825-906    AC A0A0B2UIV2.1
#=GS L7JVW8_TRAHO/1043-1129      AC L7JVW8.1
#=GS J9DL97_EDHAE/794-888        AC J9DL97.1
#=GS PTP3_ENCCU/853-934          AC Q8MTP3.1
#=GS A0A9P6L0E4_9MICR/951-1032   AC A0A9P6L0E4.1
#=GS L2GK27_VITCO/252-330        AC L2GK27.1
#=GS L2GT64_VAVCU/1389-1475      AC L2GT64.1
#=GS A0A437AN01_9MICR/833-921    AC A0A437AN01.1
#=GS J9D175_EDHAE/911-1010       AC J9D175.1
A0A4Q9LUX4_9MICR/1066-1160             .......vrvqr--------SADPEVN--ELRKKIAQ...LDNTTAEVITNPSGRSYVKLVPPYGVAEQVPLSDALVNITHVP..eKVVKEAGQEGVGIIqgtdtlplE-----ekeeeakk......
A0A059F218_9MICR/836-921               ..........tf--AKEGFERTKEQRD---FEEQLET...LANTKAEVITNPSGKQFVKFTPPVGVSEQIPANELASAEEVEF...NKNNDSGQDGLSML........QSKSS-ke............
A0A437ANB8_9MICR/1000-1066             .....kerskiv-------------------------...----EGEVITNPSGKQYVRLYPKLGVPEEIPLSDLMKKIKDPL...ESDENSGQDGISKF........SKPE--kkk...........
R0KXX2_NOSB1/893-974                   ...........p-NEGEKINQIKKLQKLIADEKRKDT...LDRIKVNTITNPDGEKRMIVNTPYGVQEMFEETEGMKRL----...SHIDPNKNVAIS--........ETPTD-d.............
R0KX08_NOSB1/893-974                   ...........p-NEGEKINQIKKLQKLIADEKRKDT...LDRIKVNTITNPDGEKRMIVNTPYGVQEMFEETEGMKRL----...SHIDPNKNVAIS--........ETPTD-d.............
A0A4Q9LJH3_9MICR/1066-1160             .......vrvqr--------SADPEVN--ELRKKIAQ...LDNTTAEVITNPSGRSYVKLVPPYGVAEQVPLSDALVNITHVP..eKVVKEAGQEGVGIIqgtdtlplE-----ekeeeakk......
C4V6P2_VAIC1/1013-1094                 ............PNEEEKIREANIFKNALAEEKKKEK...LDSIRIFSFTNPNGDKHITTVPQYGITETFEENEGMKRL----...SNIDPDKNIAIS--........ETPTE-s.............
A0A0F9ZHF1_9MICR/1013-1094             ............PNEEEKIREANIFKNALAEEKKKEK...LDSIRIFSFTNPNGDKHITTVPQYGITETFEENEGMKRL----...SNIDPDKNIAIS--........ETPTE-s.............
A0A0R0M047_9MICR/955-1044              ...........i-KKRPYLSKADEQM----LKKAIATkelLQNTRTEVLRNPNGEDYVELTPPYGVAEKVSVEDAIVNLNSPP...KGLKDAGQDGVGLL........QGTD--ttgfa.........
A0A0B2UIV2_9MICR/825-906               ..........hl--QEAQAMEIMHRKSLIEQENKKKN...LEEIDVSVITNPDGAEYVEVVPPYGVTEILPMSQAIASL----...KSIGTQSVDAVS--........EETKR-h.............
L7JVW8_TRAHO/1043-1129                 ...........i-SKRPRMSAADEKM----LKKALETrdlLQNTKTEVLTNPNGEDYVKVTPPYGVPEQVAVADAIANLNGKP...KSKKSSGQDGVSLL........QGTD--si............
J9DL97_EDHAE/794-888                   .vkktekinrsl-------QEAAKIL--SEDKEMLKR...VRDTKKKIIVNPDGKTFIELTPAFGVTERVPIDEIQRKIPSTYlssKKGIKYGQDGIE--........------eltgetkrrk....
PTP3_ENCCU/853-934                     ...........m-AHEAEVAAASEMKSRVEEEKKAKN...LEGITTEVYTNPDGSKFVEVSSPYGVPEIMTMDQAVESL----...KSVGSSSVGAVS--........EEAKK-q.............
A0A9P6L0E4_9MICR/951-1032              ...........p-NEAEKIEEAEKMTDQLEAEKRKEA...LDSIKVNTITNPDGEKHIVVVPPYGISEMFEETEGMKRL----...SHIDPSKNVAVS--........ETPTE-d.............
L2GK27_VITCO/252-330                   gadevpeyikke-------------FE--QIESMKDG...MRDAKVNVISNPDGSVIAEIKPQYGISTKMSLGEAVNKAAAMA...--------------........------ekkslagmsennln
L2GT64_VAVCU/1389-1475                 ...........i-SKRPRMSAADEKM----LKKAAETrdmLQNTKTEVLTNPNGEGYVRITPPYGVSEQVAVADAITNLNSAP...KGVKDTGQDGVGLL........QGTD--st............
A0A437AN01_9MICR/833-921               .........gim---KQETGFEKEQKE---LENQLET...LANTKKELITNPSGSQFVKLTPPLGVSEQISVEDLLKAEKKFP...SKFSESGQDGISML........QGGEE-kekts.........
J9D175_EDHAE/911-1010                  ...........l-KANGREQIIDAVIDDDCVKQALKDadaMFNTKSEIITNPSGESYIKVTPAFGVTEQIPVSDAVYNLDRIK..qSCRVTHGQLGVSVM........QESD--lksaaeekrr....
#=GC seq_cons                          ...........h..tt.phppscchhp..t.cKphcs...Lcsh+sclITNPsGcpalclsPPYGVsEplshs-uhppL.......pslcssupsulS..........ptsp..c.............
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