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Database: Pfam
Entry: Peptidase_S76
LinkDB: Peptidase_S76
Original site: Peptidase_S76 
#=GF ID   Peptidase_S76
#=GF AC   PF13611.12
#=GF DE   Serine peptidase of plant viral polyprotein, P1
#=GF AU   Rawlings ND;0000-0001-5557-7665
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:Q65730
#=GF GA   27.00 27.00;
#=GF TC   29.50 32.20;
#=GF NC   24.70 21.40;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 81514348 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0124
#=GF RN   [1]
#=GF RM   11226583
#=GF RT   Potyvirus proteins: a wealth of functions.
#=GF RA   Urcuqui-Inchima S, Haenni AL, Bernardi F;
#=GF RL   Virus Res. 2001;74:157-175.
#=GF RN   [2]
#=GF RM   19649764
#=GF RT   The complete genome sequence of Triticum mosaic virus, a new
#=GF RT   wheat-infecting virus of the High Plains.
#=GF RA   Fellers JP, Seifers D, Ryba-White M, Martin TJ;
#=GF RL   Arch Virol. 2009;154:1511-1515.
#=GF RN   [3]
#=GF RM   20565672
#=GF RT   Overview and analysis of the polyprotein cleavage sites in the
#=GF RT   family Potyviridae.
#=GF RA   Adams MJ, Antoniw JF, Beaudoin F;
#=GF RL   Mol Plant Pathol. 2005;6:471-487.
#=GF RN   [4]
#=GF RM   19386713
#=GF RT   Cassava brown streak virus (Potyviridae) encodes a putative
#=GF RT   Maf/HAM1 pyrophosphatase implicated in reduction of mutations
#=GF RT   and a P1 proteinase that suppresses RNA silencing but contains
#=GF RT   no HC-Pro.
#=GF RA   Mbanzibwa DR, Tian Y, Mukasa SB, Valkonen JP;
#=GF RL   J Virol. 2009;83:6934-6940.
#=GF DR   INTERPRO; IPR025910;
#=GF DR   MEROPS; S76;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This family is the P1 protein of the Potyviridae polyproteins
#=GF CC   that is a serine peptidase at the N-terminus. The catalytic
#=GF CC   triad in Swiss:Q65730, the ssRNA positive-strand Brome streak
#=GF CC   mosaic rymovirus, is His-311, Asp-322 and Ser-355.
#=GF SQ   4
#=GS POLG_TRMVU/213-337    AC A4KZ49.3
#=GS POLG_BSTV1/239-359    AC Q65730.1
#=GS POLG_SPMMV/569-693    AC P89201.1
#=GS K4PBT6_9POTY/250-378  AC K4PBT6.1
POLG_TRMVU/213-337               ....eyavsdtyvpqqlsrkg-----.----------SVSAKLTQRRANKI..IMRtHEVENLIRETIDLCDERQIPITFVDVKH.....KRCL.PRIPLRHMQA.KPDISeivEQGDM.YNEVGQFIEQYQ-.-NLAEPFR..VIRDYEVTRGWSGVIL.
POLG_BSTV1/239-359               .....................PAIIT.TTPVLRRQCIEKRLLRHVHQANKV..IANtVEIYDLMTETSQICAEKAIPLVFVDYEK.....KKRIrPRVPLRHVLE.SNNVD...PSDDL.YADVVPFLKHYG-.-TCGRPVG..VINPRDIKPGWSGVVL.
POLG_SPMMV/569-693               .....................ESICEgEVNIVKIFDGKPTASKKKFKTMQApnVAN.IPLDDFMQELVEICLERNTPIEIIGGVK.....SFNV.--VKLRHATR.DISKS...GEDDM.YPTEREWFCHKNKlCLCGGIERekKVRSFEVRPGWSGVIL.
K4PBT6_9POTY/250-378             deisreesvtnttktwfglrr-----.---------------SVTKVTPKL..TVK.TKVNDLIKQTLLIASELNLPIEYIDNRKhilkkRGRF.YRVPLVHCYNpDI--A...MEDDIqDPILREILSSKYM.SEQVKNFDpfLLSSKLVKPGWSGVL-v
#=GC seq_cons                    .....................................p.ph.ppp+pssKl..lsp.hclpDLhpETlpICsE+slPIpalDscK.....+tpl..RVPLRHshp.c.shu....pDDh.Yspltpalppht...ppucshc..llpsh-V+PGWSGVlL.
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