GenomeNet

Database: Pfam
Entry: PspA_IM30
LinkDB: PspA_IM30
Original site: PspA_IM30 
#=GF ID   PspA_IM30
#=GF AC   PF04012.14
#=GF DE   PspA/IM30 family
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   COG1842
#=GF GA   33.90 33.90;
#=GF TC   33.90 33.90;
#=GF NC   33.70 33.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0235
#=GF RN   [1]
#=GF RM   10629175
#=GF RT   The PspA protein of Escherichia coli is a negative regulator of
#=GF RT   sigma(54)-dependent transcription. 
#=GF RA   Dworkin J, Jovanovic G, Model P; 
#=GF RL   J Bacteriol 2000;182:311-319.
#=GF RN   [2]
#=GF RM   12079332
#=GF RT   Mechanism of Action of the Escherichia coli Phage Shock Protein
#=GF RT   PspA in Repression of the AAA Family Transcription Factor PspF. 
#=GF RA   Elderkin S, Jones S, Schumacher J, Studholme D, Buck M; 
#=GF RL   J Mol Biol 2002;320:23-37.
#=GF DR   INTERPRO; IPR007157;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family includes PspA a protein that suppresses
#=GF CC   sigma54-dependent transcription. The PspA protein, a negative
#=GF CC   regulator of the Escherichia coli phage shock psp operon, is
#=GF CC   produced when virulence factors are exported through secretins
#=GF CC   in many Gram-negative pathogenic bacteria and its homologue in
#=GF CC   plants, VIPP1, plays a critical role in thylakoid biogenesis,
#=GF CC   essential for photosynthesis. Activation of transcription by the
#=GF CC   enhancer-dependent bacterial sigma(54) containing RNA polymerase
#=GF CC   occurs through ATP hydrolysis-driven protein conformational
#=GF CC   changes enabled by activator proteins that belong to the large
#=GF CC   AAA(+) mechanochemical protein family. It has been shown that
#=GF CC   PspA directly and specifically acts upon and binds to the AAA(+)
#=GF CC   domain of the PspF transcription activator [2].
#=GF SQ   5305
#=GS T0GQX5_9SPHN/2-219        AC T0GQX5.1
#=GS A0A3L7E3J9_9GAMM/2-221    AC A0A3L7E3J9.1
#=GS A0A5C8WQR7_9RHIZ/1-222    AC A0A5C8WQR7.1
#=GS U9W5G8_9CYAN/2-223        AC U9W5G8.1
#=GS A0A1C6NRP2_9ACTN/1-229    AC A0A1C6NRP2.1
#=GS R4T2F4_9PSEU/3-244        AC R4T2F4.1
#=GS A0A074K179_9RHOB/1-225    AC A0A074K179.1
#=GS A0A401I1B2_9BACL/2-229    AC A0A401I1B2.1
#=GS A0A1V0DF78_9BACT/2-241    AC A0A1V0DF78.1
#=GS A0A0U4VUH0_9GAMM/2-218    AC A0A0U4VUH0.1
#=GS U1R097_9EURY/1-174        AC U1R097.1
#=GS A0A396U1D5_9GAMM/2-218    AC A0A396U1D5.1
#=GS A0A0Q5UZ39_9CAUL/2-230    AC A0A0Q5UZ39.1
#=GS R6R5N1_9FIRM/3-226        AC R6R5N1.1
#=GS A0A501PGN1_9PROT/2-219    AC A0A501PGN1.1
#=GS A0A0J1ILD3_BACCI/3-215    AC A0A0J1ILD3.1
#=GS H8Z454_9GAMM/2-161        AC H8Z454.1
#=GS A0A2N3UJM4_9ACTN/1-230    AC A0A2N3UJM4.1
#=GS A0A2S7TML9_9FLAO/2-231    AC A0A2S7TML9.1
#=GS A0A0C4YBS8_9BURK/1-216    AC A0A0C4YBS8.1
#=GS A0A1B9S8X5_9RHIZ/1-225    AC A0A1B9S8X5.1
#=GS A0A4Z0M6X2_9GAMM/2-221    AC A0A4Z0M6X2.1
#=GS A0A1C0AAP5_9FIRM/2-225    AC A0A1C0AAP5.1
#=GS A0A150LIY2_9BACI/3-212    AC A0A150LIY2.1
#=GS A0A2P2GF92_9ACTN/5-235    AC A0A2P2GF92.1
#=GS A0A2N0IQS0_9ACTN/28-258   AC A0A2N0IQS0.1
#=GS A0A117IWW6_9ACTN/1-224    AC A0A117IWW6.1
#=GS A0A1I6W3Q9_9BACL/2-233    AC A0A1I6W3Q9.1
#=GS A0A4R2NC95_9BACL/1-217    AC A0A4R2NC95.1
#=GS A0A1C0AS05_9ACTN/3-233    AC A0A1C0AS05.1
#=GS A0A5C8JYV4_9ACTN/2-233    AC A0A5C8JYV4.1
#=GS A0A1H1TKY3_9BACL/2-240    AC A0A1H1TKY3.1
#=GS A0A0B0HXR8_9BACL/2-232    AC A0A0B0HXR8.1
#=GS A0A4P7JN45_9GAMM/2-231    AC A0A4P7JN45.1
#=GS A0A509E1C1_9RHIZ/2-218    AC A0A509E1C1.1
#=GS A0A1I3KT96_9BACL/2-232    AC A0A1I3KT96.1
#=GS A0A0X3XFL5_9ACTN/1-224    AC A0A0X3XFL5.1
#=GS A0A1N7IZR1_9GAMM/5-216    AC A0A1N7IZR1.1
#=GS A0A4R2Q0P4_9PSEU/3-244    AC A0A4R2Q0P4.1
#=GS M1NQM4_9CORY/3-240        AC M1NQM4.1
#=GS D1BD38_SANKS/6-239        AC D1BD38.1
#=GS A0A3S5IL88_9ACTN/3-234    AC A0A3S5IL88.1
#=GS A0A495XK01_9PSEU/3-244    AC A0A495XK01.1
#=GS C8VVV0_DESAS/2-224        AC C8VVV0.1
#=GS A0A6A2ZM52_HIBSY/62-166   AC A0A6A2ZM52.1
#=GS A0A2H5AXF0_9ACTN/1-230    AC A0A2H5AXF0.1
#=GS A0A5J9VL55_9POAL/58-278   AC A0A5J9VL55.1
#=GS A0A1Y5K9V8_9BACL/2-230    AC A0A1Y5K9V8.1
#=GS A0A3A1QVA8_9BACI/3-215    AC A0A3A1QVA8.1
#=GS R7BEP7_9FIRM/2-225        AC R7BEP7.1
#=GS A0A4P6Q123_9ACTN/2-233    AC A0A4P6Q123.1
#=GS A0A2N5N0Y9_9BACL/2-233    AC A0A2N5N0Y9.1
#=GS A0A6L7HNT5_BACAN/4-220    AC A0A6L7HNT5.1
#=GS T0JC30_9SPHN/64-283       AC T0JC30.1
#=GS A0A1D7W7I6_9MICO/2-232    AC A0A1D7W7I6.1
#=GS A0A1A5YDS1_9BACL/2-227    AC A0A1A5YDS1.1
#=GS A0A0B4RE53_9BACL/3-211    AC A0A0B4RE53.1
#=GS A0A1Q5N1B7_9ACTN/1-229    AC A0A1Q5N1B7.1
#=GS Q5L2W4_GEOKA/2-206        AC Q5L2W4.1
#=GS L8LHH0_9CHRO/2-218        AC L8LHH0.1
#=GS A0A1T5KIV3_9MICO/5-237    AC A0A1T5KIV3.1
#=GS A0A158II46_9BURK/2-223    AC A0A158II46.1
#=GS M1VMH1_CYAM1/65-284       AC M1VMH1.1
#=GS A0A0J6CW63_9BACI/3-222    AC A0A0J6CW63.1
#=GS A0A0B8T8R3_9SPHI/2-225    AC A0A0B8T8R3.1
#=GS I0YQ10_COCSC/11-234       AC I0YQ10.1
#=GS A0A5B1BKH9_9FLAO/2-232    AC A0A5B1BKH9.1
#=GS A0A0D8D2U7_9GAMM/2-218    AC A0A0D8D2U7.1
#=GS A0A2V3VI83_9BACI/2-223    AC A0A2V3VI83.1
#=GS A0A2V3JEK3_9EURY/2-232    AC A0A2V3JEK3.1
#=GS A0A2I0SFA9_9ACTN/3-234    AC A0A2I0SFA9.1
#=GS A0A516RKS9_STRST/3-233    AC A0A516RKS9.1
#=GS A0A1Q4RII9_9CYAN/130-224  AC A0A1Q4RII9.1
#=GS A0A4Y6V021_9BACL/2-221    AC A0A4Y6V021.1
#=GS A0A1I6QPJ5_9BACL/2-221    AC A0A1I6QPJ5.1
#=GS A0A4Q9DK03_9BACL/2-221    AC A0A4Q9DK03.1
#=GS A0A1S1N0A4_9GAMM/2-217    AC A0A1S1N0A4.1
#=GS S4MK13_9ACTN/17-247       AC S4MK13.1
#=GS C6Q2Z5_9CLOT/2-216        AC C6Q2Z5.1
#=GS A0A2K1KBK5_PHYPA/104-336  AC A0A2K1KBK5.1
#=GS A0A509C5W4_9ENTR/10-102   AC A0A509C5W4.1
#=GS A0A559KGL2_9BACL/2-220    AC A0A559KGL2.1
#=GS A0A2U1K4I1_9BACI/1-214    AC A0A2U1K4I1.1
#=GS F2FAS4_SOLSS/3-208        AC F2FAS4.1
#=GS E3ECB0_PAEPS/2-215        AC E3ECB0.1
#=GS G2G164_9FIRM/2-224        AC G2G164.1
#=GS W1TQF4_9ACTO/6-237        AC W1TQF4.1
#=GS A0A1S8FCM7_9BURK/4-221    AC A0A1S8FCM7.1
#=GS A0A2H5Z877_9BACT/2-233    AC A0A2H5Z877.1
#=GS A0A1I0BGU3_9BACT/2-233    AC A0A1I0BGU3.1
#=GS A0A4P7JJ40_9GAMM/2-229    AC A0A4P7JJ40.1
#=GS A0A0A3JQP8_9BACI/3-219    AC A0A0A3JQP8.1
#=GS B5H9W5_STRE2/5-236        AC B5H9W5.1
#=GS A0A388KUB4_CHABU/206-435  AC A0A388KUB4.1
#=GS A0A344TVX7_9ACTN/5-237    AC A0A344TVX7.1
#=GS A0A1A9GEN1_9RHIZ/160-287  AC A0A1A9GEN1.1
#=GS B1VDD1_CORU7/3-243        AC B1VDD1.1
#=GS A0A1W1XTQ5_9CLOT/2-218    AC A0A1W1XTQ5.1
#=GS L0EHS8_THECK/3-96         AC L0EHS8.1
#=GS A0A073AXA1_9PSEU/3-243    AC A0A073AXA1.1
#=GS D8G587_9CYAN/36-234       AC D8G587.1
#=GS A0A1Y0GW91_9BACT/1-220    AC A0A1Y0GW91.1
#=GS A0A1L3MIH7_9MICO/6-238    AC A0A1L3MIH7.1
#=GS M8AUW8_TRIUA/43-273       AC M8AUW8.1
#=GS A0A4S5E3P4_9MICC/5-239    AC A0A4S5E3P4.1
#=GS A0A1C7P3C6_9RHIZ/169-379  AC A0A1C7P3C6.1
#=GS A0A4T2A6B8_9RHOB/3-242    AC A0A4T2A6B8.1
#=GS S7TYM7_9DELT/2-219        AC S7TYM7.1
#=GS A0A3B6ASB3_WHEAT/83-313   AC A0A3B6ASB3.1
#=GS A0A4T3EZI3_9SPHN/6-222    AC A0A4T3EZI3.1
#=GS A0A5S4ZC86_9ACTN/3-244    AC A0A5S4ZC86.1
#=GS V6M2B1_9BACL/2-220        AC V6M2B1.1
#=GS I4AKI1_BERLS/3-238        AC I4AKI1.1
#=GS A0A199VPL5_ANACO/69-287   AC A0A199VPL5.1
#=GS A0A0P6WGX3_9BACI/3-215    AC A0A0P6WGX3.1
#=GS B0RAN0_CLAMS/1-207        AC B0RAN0.1
#=GS A0A061EJD7_THECC/79-301   AC A0A061EJD7.1
#=GS C1EHE7_MICCC/191-407      AC C1EHE7.1
#=GS A0A3N1JY74_9BACT/2-220    AC A0A3N1JY74.1
#=GS A0A285R0M3_9SPHN/2-219    AC A0A285R0M3.1
#=GS A0A5E4GH20_PRUDU/2-226    AC A0A5E4GH20.1
#=GS A0A1X1R3E2_9MYCO/3-243    AC A0A1X1R3E2.1
#=GS A0A166MG87_9ACTN/3-243    AC A0A166MG87.1
#=GS G2NDV0_STREK/1-229        AC G2NDV0.1
#=GS A0A0D3VET6_9BACL/2-220    AC A0A0D3VET6.1
#=GS A0A0S2K6P9_9GAMM/2-228    AC A0A0S2K6P9.1
#=GS R9N6U3_9FIRM/6-227        AC R9N6U3.1
#=GS A0A3N5DTR3_9SPHN/43-261   AC A0A3N5DTR3.1
#=GS A0A433XC34_9BACL/3-229    AC A0A433XC34.1
#=GS A0A2V4B1U2_9PSEU/3-244    AC A0A2V4B1U2.1
#=GS A0A504DAS9_9RHIZ/3-234    AC A0A504DAS9.1
#=GS A0A656HJ53_THINJ/4-221    AC A0A656HJ53.1
#=GS A0A0Q5CMY6_9MICO/5-236    AC A0A0Q5CMY6.1
#=GS A0A1R1D9R1_9BACL/2-219    AC A0A1R1D9R1.1
#=GS A0A1U7XX01_NICSY/65-286   AC A0A1U7XX01.1
#=GS A0A505CZ70_9ACTN/3-233    AC A0A505CZ70.1
#=GS A0A498QPH5_9MYCO/3-243    AC A0A498QPH5.1
#=GS A0A0Q6VID7_9ACTN/2-233    AC A0A0Q6VID7.1
#=GS A0A3G9IQD4_9ACTN/3-233    AC A0A3G9IQD4.1
#=GS A0A4Q0VTK3_9BACI/2-213    AC A0A4Q0VTK3.1
#=GS A0A511UUD3_9BACI/2-223    AC A0A511UUD3.1
#=GS K6CJD7_9BACI/2-223        AC K6CJD7.1
#=GS A0A085GAD4_9GAMM/2-221    AC A0A085GAD4.1
#=GS D7E237_NOSA0/2-218        AC D7E237.1
#=GS I4AM00_BERLS/2-232        AC I4AM00.1
#=GS A0A2T1CQL4_9CYAN/40-237   AC A0A2T1CQL4.1
#=GS V6JTV3_STRRC/1-229        AC V6JTV3.1
#=GS A0A151TG22_CAJCA/64-284   AC A0A151TG22.1
#=GS A0A543CB67_9ACTN/3-242    AC A0A543CB67.1
#=GS A0A420XPB1_9ACTN/2-232    AC A0A420XPB1.1
#=GS A0A1I4A1D7_9ACTN/3-244    AC A0A1I4A1D7.1
#=GS A0A5C1QLN8_9SPIO/8-228    AC A0A5C1QLN8.1
#=GS A0A238YBT2_9ACTN/2-232    AC A0A238YBT2.1
#=GS A0A2N4XU18_9RHOO/2-230    AC A0A2N4XU18.1
#=GS A0A5C5W8K9_9BACT/2-224    AC A0A5C5W8K9.1
#=GS A0A329KMR1_9BACL/2-229    AC A0A329KMR1.1
#=GS H6KZ27_SAPGL/3-233        AC H6KZ27.1
#=GS A0A0D2RM13_GOSRA/76-296   AC A0A0D2RM13.1
#=GS A0A1L8P960_9LACT/2-226    AC A0A1L8P960.1
#=GS A0A1Q4YNA7_9ACTN/1-230    AC A0A1Q4YNA7.1
#=GS A0A291Q5U6_9ACTN/1-229    AC A0A291Q5U6.1
#=GS A0A0Q4FB73_9MICO/5-238    AC A0A0Q4FB73.1
#=GS A0A6C0QMT0_9BACL/2-221    AC A0A6C0QMT0.1
#=GS A0A0D2PRT2_GOSRA/80-304   AC A0A0D2PRT2.1
#=GS A0A2U3C2U4_9ACTN/3-233    AC A0A2U3C2U4.1
#=GS A0A3A9K8G6_9BACI/3-215    AC A0A3A9K8G6.1
#=GS A0A1L7CTA5_9CORY/3-243    AC A0A1L7CTA5.1
#=GS A0A1B8VYU8_9BACI/2-222    AC A0A1B8VYU8.1
#=GS A0A256KKN2_9EURY/2-232    AC A0A256KKN2.1
#=GS A0A1B8WHI9_9BACI/2-225    AC A0A1B8WHI9.1
#=GS A0A345NQJ4_9MICO/6-239    AC A0A345NQJ4.1
#=GS A0A4R4LXH1_9ACTN/1-226    AC A0A4R4LXH1.1
#=GS D9SYM9_MICAI/3-243        AC D9SYM9.1
#=GS A0A0W8EJF4_9BACT/2-232    AC A0A0W8EJF4.1
#=GS A0A3G9IU26_9BACL/2-220    AC A0A3G9IU26.1
#=GS A0A0M2PTL9_PROHO/1-60     AC A0A0M2PTL9.1
#=GS A0A2R7QS05_9MICC/5-239    AC A0A2R7QS05.1
#=GS A0A024P3L7_9BACI/3-213    AC A0A024P3L7.1
#=GS A0A0F0LWB9_9MICO/5-238    AC A0A0F0LWB9.1
#=GS A0A6B3GQK0_9ACTN/5-70     AC A0A6B3GQK0.1
#=GS A0A5N0T7S2_9GAMM/2-222    AC A0A5N0T7S2.1
#=GS A0A652KB23_9ACTN/5-235    AC A0A652KB23.1
#=GS A0A3N0BV80_9MICC/5-237    AC A0A3N0BV80.1
#=GS K2FLN2_9BACI/3-204        AC K2FLN2.1
#=GS A0A1C6UCY5_9ACTN/3-243    AC A0A1C6UCY5.1
#=GS A0A2U0H789_9MICO/5-236    AC A0A2U0H789.1
#=GS A0A160KQ67_9MICO/6-239    AC A0A160KQ67.1
#=GS A0A179SNR4_9BACI/3-214    AC A0A179SNR4.1
#=GS A0A372SUB7_9FIRM/2-224    AC A0A372SUB7.1
#=GS A0A545THX7_9GAMM/2-223    AC A0A545THX7.1
#=GS A0A552ACR7_MICAE/2-218    AC A0A552ACR7.1
#=GS A0A4V1DI35_9SYNE/2-218    AC A0A4V1DI35.1
#=GS A0A1H9BSC4_9FIRM/2-225    AC A0A1H9BSC4.1
#=GS A0A1W2CUQ4_9RHIZ/2-230    AC A0A1W2CUQ4.1
#=GS A0A1Q3GZY7_9BACT/2-220    AC A0A1Q3GZY7.1
#=GS A3DI31_HUNT2/2-234        AC A3DI31.1
#=GS M0MRX3_HALMO/2-232        AC M0MRX3.1
#=GS A0A127A1K1_9MICC/15-247   AC A0A127A1K1.1
#=GS A0A3S0BZ86_9BACL/2-230    AC A0A3S0BZ86.1
#=GS A0A0C2B7V2_9ACTN/1-229    AC A0A0C2B7V2.1
#=GS A0A4Q5Z096_9ACTN/3-233    AC A0A4Q5Z096.1
#=GS A0A432W6T6_9GAMM/2-218    AC A0A432W6T6.1
#=GS A0A1I0NME3_9EURY/2-231    AC A0A1I0NME3.1
#=GS D1CBK0_THET1/3-220        AC D1CBK0.1
#=GS A0A1X1DB34_9GAMM/2-219    AC A0A1X1DB34.1
#=GS B1M6D9_METRJ/2-224        AC B1M6D9.1
#=GS A0A109LNW0_9SPHN/1-194    AC A0A109LNW0.1
#=GS A0A1E8FV99_9MICC/5-237    AC A0A1E8FV99.1
#=GS B7FWP5_PHATC/57-284       AC B7FWP5.1
#=GS A0A1U7P1K3_9DEIO/2-219    AC A0A1U7P1K3.1
#=GS A0A2R8BAU3_9RHOB/6-223    AC A0A2R8BAU3.1
#=GS I7KIV3_9CORY/3-245        AC I7KIV3.1
#=GS A0A314KTA4_NICAT/72-293   AC A0A314KTA4.1
#=GS A0A2W1ZLL8_9MICO/5-237    AC A0A2W1ZLL8.1
#=GS A0A3Q9QT98_9BACI/3-213    AC A0A3Q9QT98.1
#=GS A0A1H7RCH0_9GAMM/2-219    AC A0A1H7RCH0.1
#=GS I1DWW1_9GAMM/2-218        AC I1DWW1.1
#=GS K0SI43_THAOC/52-300       AC K0SI43.1
#=GS PSPA_SHIFL/2-219          AC P0AFM8.2
#=GS A0A098EW36_9BACI/3-214    AC A0A098EW36.1
#=GS B7GJ07_ANOFW/16-221       AC B7GJ07.1
#=GS A0A1M7GZM0_9RHOB/4-224    AC A0A1M7GZM0.1
#=GS A0A268ECZ8_9BACI/2-218    AC A0A268ECZ8.1
#=GS A0A269W3P4_9BACL/3-218    AC A0A269W3P4.1
#=GS H3SCK4_9BACL/3-223        AC H3SCK4.1
#=GS A0A0A7EH24_9GAMM/2-220    AC A0A0A7EH24.1
#=GS W5WID4_9PSEU/3-243        AC W5WID4.1
#=GS A0A2N0WUW6_9GAMM/2-219    AC A0A2N0WUW6.1
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#=GS A0A1H1ATP4_9BACI/3-222    AC A0A1H1ATP4.1
#=GS Q2J755_FRACC/3-239        AC Q2J755.1
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#=GS C0B449_9GAMM/2-94         AC C0B449.1
#=GS L0JNR9_NATP1/2-232        AC L0JNR9.1
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#=GS Q97M85_CLOAB/2-217        AC Q97M85.1
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