#=GF ID   PylD_N
#=GF AC   PF21455.4
#=GF DE   Pyrrolysine biosynthesis protein PylD, N-terminal domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE   ECOD:EF20292
#=GF GA   27.00 27.00;
#=GF TC   27.20 61.50;
#=GF NC   26.90 21.40;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 8 -Z 90746521 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0014
#=GF RC   Paper describing PDB structure 4j43
#=GF RN   [1]
#=GF RM   23720358
#=GF RT   Structure and reaction mechanism of pyrrolysine synthase (PylD).
#=GF RA   Quitterer F, Beck P, Bacher A, Groll M;
#=GF RL   Angew Chem Int Ed Engl. 2013;52:7033-7037.
#=GF RC   Paper describing PDB structure 4q39
#=GF RN   [2]
#=GF RM   24916332
#=GF RT   The formation of pyrroline and tetrahydropyridine rings in amino
#=GF RT   acids catalyzed  by pyrrolysine synthase (PylD).
#=GF RA   Quitterer F, Beck P, Bacher A, Groll M;
#=GF RL   Angew Chem Int Ed Engl. 2014;53:8150-8153.
#=GF DR   INTERPRO; IPR048757;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found at the N-terminal end of Pyrrolysine
#=GF CC   biosynthesis protein PylD from Methanosarcina acetivorans, a
#=GF CC   dehydrogenase that catalyses the final step in the biosynthesis
#=GF CC   of the amino acid pyrrolysine [1,2].
#=GF SQ   69
#=GS A0A0E3WZ19_METMT/8-119   AC A0A0E3WZ19.1
#=GS A0A4Z0QP51_9FIRM/8-124   AC A0A4Z0QP51.1
#=GS A0A415DY88_9FIRM/9-126   AC A0A415DY88.1
#=GS A0A086YMW5_9FIRM/8-126   AC A0A086YMW5.1
#=GS A0A8J8B3Y9_9FIRM/9-126   AC A0A8J8B3Y9.1
#=GS A0A0B7MR06_9FIRM/8-126   AC A0A0B7MR06.1
#=GS A0AA51UEG2_9EURY/8-119   AC A0AA51UEG2.1
#=GS A0A4Z0QXI5_9FIRM/8-124   AC A0A4Z0QXI5.1
#=GS A0A1M6F4J1_9FIRM/10-126  AC A0A1M6F4J1.1
#=GS A0A562GKG4_9FIRM/8-125   AC A0A562GKG4.1
#=GS A0A845QFF7_9FIRM/9-126   AC A0A845QFF7.1
#=GS M9SDR3_METAX/1-117       AC M9SDR3.1
#=GS A0AA43ZX36_UNCTM/10-124  AC A0AA43ZX36.1
#=GS A0A1Q9JIY2_9FIRM/10-126  AC A0A1Q9JIY2.1
#=GS A0A1W2CQ32_9BACT/8-126   AC A0A1W2CQ32.1
#=GS A0A1M6IHU4_9FIRM/8-121   AC A0A1M6IHU4.1
#=GS A0A0U1L1K6_9FIRM/9-126   AC A0A0U1L1K6.1
#=GS M4YLM0_THEXX/8-124       AC M4YLM0.1
#=GS R4KJ12_9FIRM/11-126      AC R4KJ12.1
#=GS A0A4Z0R3W4_9FIRM/8-120   AC A0A4Z0R3W4.1
#=GS E5Y2Y5_BILW3/8-125       AC E5Y2Y5.1
#=GS A0A4E0Q9S1_9EURY/8-119   AC A0A4E0Q9S1.1
#=GS L0KSD7_METHD/8-119       AC L0KSD7.1
#=GS A0A366HZA8_9FIRM/8-125   AC A0A366HZA8.1
#=GS A0A858BW57_9FIRM/8-126   AC A0A858BW57.1
#=GS H5Y373_9FIRM/8-124       AC H5Y373.1
#=GS A0A1G9HBX3_9FIRM/8-125   AC A0A1G9HBX3.1
#=GS A0A840UMS6_9FIRM/8-126   AC A0A840UMS6.1
#=GS A0A0L6JRF8_9FIRM/8-126   AC A0A0L6JRF8.1
#=GS A0A6P1MID1_9FIRM/9-126   AC A0A6P1MID1.1
#=GS A0A099S922_9FIRM/8-119   AC A0A099S922.1
#=GS G7WEU1_DESOD/8-123       AC G7WEU1.1
#=GS F7XLV7_METZD/8-119       AC F7XLV7.1
#=GS A0A0W7TJS2_9ARCH/8-124   AC A0A0W7TJS2.1
#=GS K4LKP9_THEPS/8-126       AC K4LKP9.1
#=GS A0A0Q4BDZ6_9ARCH/8-124   AC A0A0Q4BDZ6.1
#=GS A0A1Q6DT49_METT1/8-123   AC A0A1Q6DT49.1
#=GS A0A1W2BE48_9FIRM/15-133  AC A0A1W2BE48.1
#=GS A0A0F2J7V6_9FIRM/8-124   AC A0A0F2J7V6.1
#=GS C8VVD4_DESAS/8-126       AC C8VVD4.1
#=GS A0A1Q8QIU1_9FIRM/8-124   AC A0A1Q8QIU1.1
#=GS A0A410PWR4_9FIRM/24-141  AC A0A410PWR4.1
#=GS H5XS84_9FIRM/8-123       AC H5XS84.1
#=GS A0A1C3F2W5_9FIRM/8-126   AC A0A1C3F2W5.1
#=GS D7E780_METEZ/8-119       AC D7E780.1
#=GS A0AAE4MJW0_9EURY/8-119   AC A0AAE4MJW0.1
#=GS H5XXG9_9FIRM/8-124       AC H5XXG9.1
#=GS A0A0E3L7D7_9EURY/8-119   AC A0A0E3L7D7.1
#=GS A0A099RU08_9FIRM/8-124   AC A0A099RU08.1
#=GS A0A0X8V1N8_THEX5/8-124   AC A0A0X8V1N8.1
#=GS A0A133VJ69_9EURY/43-153  AC A0A133VJ69.1
#=GS A0A1W1HAY0_9BACT/8-131   AC A0A1W1HAY0.1
#=GS A0A8T9VQ90_9EURY/10-122  AC A0A8T9VQ90.1
#=GS A0A1H0KHX4_9BACT/2-115   AC A0A1H0KHX4.1
#=GS R9T6N8_METII/1-117       AC R9T6N8.1
#=GS A0AAF0S5D8_9ARCH/9-123   AC A0AAF0S5D8.1
#=GS A0A0A7LDQ5_9ARCH/8-124   AC A0A0A7LDQ5.1
#=GS A0A562GF58_9FIRM/8-124   AC A0A562GF58.1
#=GS A0A1W1YJ27_9FIRM/8-126   AC A0A1W1YJ27.1
#=GS D5E9G1_METMS/8-119       AC D5E9G1.1
#=GS A0A348AJN7_9FIRM/8-125   AC A0A348AJN7.1
#=GS D9QUB4_ACEAZ/8-124       AC D9QUB4.1
#=GS A0A942J1L1_9FIRM/9-122   AC A0A942J1L1.1
#=GS Q24MJ7_DESHY/8-123       AC Q24MJ7.1
#=GS A0A6B9TA40_9ARCH/8-122   AC A0A6B9TA40.1
#=GS PYLD_METAC/8-119         AC Q8TUC1.1
#=GS D5X8E2_THEPJ/8-123       AC D5X8E2.1
#=GS A0A484F5W1_9EURY/8-119   AC A0A484F5W1.1
#=GS A0A1I1Z155_9FIRM/14-126  AC A0A1I1Z155.1
A0A0E3WZ19_METMT/8-119              .............................d-LEDLLNKLNANNDIIKGATGED.ISQI..CE..E..AYG.......T........KPGNQ....KVGIVPITAGNGIIGNFSASLLAITE.YFGLEGFITEHPDMTGYYEAVAGGADIILMADDHIFIAHNLSNGKI-a...........
A0A4Z0QP51_9FIRM/8-124              ...........................dvv---EIASTLEEYNADLVRMTGCS.LREI..AA..H..AVG.......Kvv...sggYVQNP....KVAVIPMTCGQGIIKGFVESVASIID.YLGFDVVITNSRDAGGVAEAVQNSSEILFMADDDRFVAVNVRTGKVS............
A0A415DY88_9FIRM/9-126              ..........................veym-----IDGMDAYNQSLMQKIGVD.LAGL..AM..R..TFH.......Mtqa.dfdrARACN....KVAVVPITQGEGIIGSFSESVAAIVR.SMGFCADVMPHTDVDGIYDGYQRGCNIFFFADDIRYLALNTKTNKAS............
A0A086YMW5_9FIRM/8-126              ..........................dvly----IAESLKEYDKQLVKNVGKS.LAGI..AA..H..AIG.......Rtek.eiydLHHAT....SVAIIPVTCGEGIINGFSGSVQKIIE.HLGFTAFVTGHKDVGGLAEAVKKGAKVIFLADDDHFVAINISTGRVV............
A0A8J8B3Y9_9FIRM/9-126              ...........................lad----IEDGIKEYQQILKAKTGLN.YAAL..AA..K..ASGcsagdieR........ASLSL....KVAVVPVTSGLGMIGSFAQSVAAVVG.VMGFQTFVTSHTDVDGIYEAYQNGADMVFIADDNRFISMNLHKKKM-a...........
A0A0B7MR06_9FIRM/8-126              .............................d-VEEIHRELDLYDSELIEKTGLS.LRQM..AC..M..AAGip...ekTv.....ieRALTC....KAAVIPITVGEGIIPSFTTAVQSIIQ.HLGFQAVVTDETDVAGIAEAISHGANLLFMADDLKFIALNVQTGVA-v...........
A0AA51UEG2_9EURY/8-119              .............................d-LENLSMQLEENDEIARRVTGLD.IRGI..CE..A..LYG.......T........KPGSE....KVGIIPITAGNGVIGNFTSSLLFIAQ.YFGFEGFITEHPDVTGYYEAVSQGADIIMMADDHIFTAHNLRNEKIV............
A0A4Z0QXI5_9FIRM/8-124              ...........................dvv---KIATSLEDYNSQLVRMTGCS.LREL..AA..H..AVA.......Kgs...nedYVQKL....NVAVIPMTCGQGVIEGFVESVASIIS.YLGFNAVITKSRDAGGVAEAVQNGSDILFMADDDRFVAINVKTGKVS............
A0A1M6F4J1_9FIRM/10-126             .......................idirynm----NSLENDLKMKTNMGYVELA.AKSCgnEI..Q..GFS.......R........FVESA....SIAVIPVTTGQGVIGSFTDSVCSILS.YMGFQAFITEGTDVNGLYEAFMKGVDIVFMADDDRFIAINRKNGSVS............
A0A562GKG4_9FIRM/8-125              ...........................did---TVGEKLYEYNEHLRHILGRS.LAEI..AA..Y..SLG.......Kkpa..dfaGKHNV....PIGVIPVSCGQGVIGGFAQTVQQIIE.FLGFCSFVTSQSDVGGLAEAVRRGAQVVFLADDDHFVAIHLAGGKVV............
A0A845QFF7_9FIRM/9-126              .........................ityml------DGMEEYNRDLAAKTGMD.LAAL..MA..D..TFC.......Vskf.dlaaAQKNI....KVAVVPITQGEGIIGSFSESVAAIVR.SMGFCADVMPNTDVDGIYDATLGGYDVLFFADDIRYLALNIRSGKAS............
M9SDR3_METAX/1-117                  .............................m-ISGLSDGLSDIDRMLMRDTGMN.LLTL..GF..R..AIG.......Ada...sevDVKRF....KAASVPITSGLGIIGGFSRSVADIVR.DMGIDCFVTEHTDVWGFGEAIDRGADIILMADDEQYMAYSVAAGRY-a...........
A0AA43ZX36_UNCTM/10-124             ........................wgvpdd--------KLDLDGRLMKATGKT.VKGI..AM..E..AAG.......Leg...ddyDFSRF....SAAAVPITSGLGIIGGFAKSVDAIVT.RLGMRSRVTDATDVAGFAEATRDGADIIMMSDDPVFMAYNTRER---ayt.........
A0A1Q9JIY2_9FIRM/10-126             sdieagmgeysaglqrkigmtlmefsrwvc-----------------------.--GL..DE..Q..AFQ.......Q........MQKRY....RVGVVPVTQGQGLIRGFSEALCAISR.NIGFDTEISQKTDVDGIYDCIHRNRKILLCADDERYIALNAEKGI--ig..........
A0A1W2CQ32_9BACT/8-126              .............................d-INTIVKNLDNYNRELIEKTGHS.LLGI..AC..H..ACG.......Rkka.eilkLIDDF....AVSVVPVTAGQGIITTFSDTVAAIMN.YLGFQVSVTTATDTAGVAEAFENKAHGIMMSDDNRFVGLNLTLQQ--va..........
A0A1M6IHU4_9FIRM/8-121              ............................di--DVIERQLQTYEELFIRQTGHT.MEAI..AR..K..AAGi.....sG........KVKRR....KAGVVPVTSGLGVISGFSRTVGAILH.HCQVETLVTEETDVAGLQQAYLSGCGMAFLADDKVCAAFGI------gqkahs......
A0A0U1L1K6_9FIRM/9-126              ........................icyvgq-------RLENYDLQLFQRTGKG.LAGI..AA..H..ALG.......Kvpe.dfaaVRQGI....SVGIVPIAYGQGIINGFSETLQDIIE.FLGFFAFVTESPNISGLGEAISRGAKLIFLADDDKFVALNIASGKVS............
M4YLM0_THEXX/8-124                  .............................m-IDGLSDELSALDKYLIGATGMD.IRTL..GF..R..AIG.......Vdp...tkvDITKY....KAASVPITSGLGVIGGFSKSVADIVR.DMGMECFVTERTDVWGFGEAIDRGADIILMADDEQYMAYSVAAGKYS............
R4KJ12_9FIRM/11-126                 ......................gletelrd-----YEDELLSKLGYSLKEIACkAAGI..KV..T..YFD.......T........LVKDH....SIAVIPITAGKGLIGGFVQSVAAIIK.YLGFEVFISEATDVAGFAEGLEQGASVLFMADDNRFLAFNKFNGHL-i...........
A0A4Z0R3W4_9FIRM/8-120              .............................d-IDLIETQLQDYEDLFIRQTGYT.MEEI..AQ..K..AVGl.....tK........NTKRI....KTAVISVTSGLGIITGFSQAVGAILR.HCRVETLIAEKTDVAGLQQAYLSKCGITFLADDCVCAA---------fgigsavh....
E5Y2Y5_BILW3/8-125                  ...........................dia---GIEAEWATYERRLEELTGDD.LLTL..TA..R..TLGid...peTa.....rsGVREL....RVGAIPISSGEGLIGGFADSLASIAG.HLGFEADVLP-ADVPGFQLAKSGGFDLFIWADDDTYLAENILTGTV-g...........
A0A4E0Q9S1_9EURY/8-119              .............................d-LENLSVQLEENDEIVRRVTGLN.IKQI..CE..E..LYG.......K........ELGFP....KIGIIPITAGNGIIGNFTSSLLFIVQ.YFGLEGFITEHPDITGYYEAVSQGADIILMADDHIFVAHNLRNEKIV............
L0KSD7_METHD/8-119                  .............................d-LDNLSAQFEESESTIERVTGTR.LTDI..CK..E..LYG.......K........DLGSE....KVGIIPITAGNGIISNFTSSLLFIAQ.RLGLEGFITQHTDVAGYYEAIRDGADILLMADDHLFIAHNLRNGKLV............
A0A366HZA8_9FIRM/8-125              .............................d-IQSIIKQYRKNEEFFIKNFKFS.LLEI..GN..K..AVN.......Naa...skeQLKNL....KVACIPITSGFGEISNFSQIVCTILTdCCGVNAFVTKQKNVAGIQEAYEQKSDIIFMADDNTFTAFHLKKN---lym.........
A0A858BW57_9FIRM/8-126              ...........................wie---HMLDGMDDYNRQLQDKIGLN.LAEL..TC..K..TWHlteaefeK........ARNNH....RIAIVPVTQGEGIISAFSQSVAAIVY.SMGFQAFVTGCSDVDGIWEGTKQGCDIFFLADDTRYLALNIKSGKAS............
H5Y373_9FIRM/8-124                  .............................d-VNQITAALGDYNEELVRTTGCS.LNEI..AA..L..ASG.......Kei...dcpDKQNP....LVAVIPMTCGQGIIEGFVESVAGIIA.YLGFQAVVTKNSDAGGVAEAVKKGADILFMADDDQFVAINIRTGKVS............
A0A1G9HBX3_9FIRM/8-125              ............................di--AEIPKIIDQYDRELEAKIGLN.LFDL..AV..R..AAG.......Rnpd..evtKTDKK....RAAVIPVTAGRGEIAGFCEAIKAVLS.RLGLEAFIPEKTDVAGLKSALEKNCDMAFMADDNSFLALDLQKGR--wm..........
A0A840UMS6_9FIRM/8-126              ..........................difh----ISEQLTKYDSDLRRIIDMG.LNEL..GA..A..AAGanltelqK........YIKGE....CVGIVPITSGEGIINSFSQTIKSIID.FTGLTSFITNATDVAGIAEAVERKATMLFIADDAT------------ckllhlkksiia
A0A0L6JRF8_9FIRM/8-126              ...........................dic---EVSKNLMSYNKELITKTGTD.LAGI..AL..H..ATGi....yeKyy....nsYKVNS....HIAVVPVSCGDGVINGFCETIKDIIN.ILGFSSYVTSEKDISGIEEAYQRMADVIFIADDEKFIALNTLSRKV-v...........
A0A6P1MID1_9FIRM/9-126              ..........................ieym-----LDGMEEYNKQLKIKTGMD.LADF..IK..D..TFN.......Mqea.vfqqARDTK....KIAVVPITQGEGIISSFSESVAAIIK.SIGFNALVTEHTDIDGIYEGTEKGCDIFFFADDARYLALNIKSGNV-c...........
A0A099S922_9FIRM/8-119              .............................d-IDLIETQLQNYENLFIRQTGCT.MEEI..AQ..K..AVGl.....rE........NTKRI....KTAVISVTSGLGIIAGFSQAVGAILR.HHRVETLITEKTDVAGLQQAYLSKCGIAFLADDCVCAA---------lgigsav.....
G7WEU1_DESOD/8-123                  .............................d-VAEISRQMSDYNSTLIQKTGCS.LREL..AA..W..AAG.......V........HLDRElpqpKVAIIPMTCGQGIIEGFSQSVAGIVQ.FLGFSPVITESRDAGGVAEAIEGGAEIIFMADDDRFVAVNVKSGKVS............
F7XLV7_METZD/8-119                  .............................d-LENLLDKLEYNEKVIKKVTGFE.IKQI..CE..E..TYG.......T........FPDSE....VVGIVPVTSGNGIIDNFTASLAAIVN.HFGLKGFVTEHTDISGYNEAVSRRADIIMMADDHIFIAHNLKNGKIS............
A0A0W7TJS2_9ARCH/8-124              .............................m-ISGLSGELSDIDKMLIRDTGMD.LRTL..GF..R..AIG.......Vdp...akvDVTKY....RAAAVPITSGLGIISKFSRSVADIVS.AMGIECTVTEHTDVWGFGDALDLGADIILMADDEQYMAYSVAAGKY-a...........
K4LKP9_THEPS/8-126                  ...........................dve---RIAEEIGGYDEELLGKTGLT.LRQI..AC..R..AAGiseklleQ........AAGRL....PVAVIPVTAGQGVIPFFTQAVQAVVR.HLGFAAAIPGGSDVVGLAEAVAEGARIIFLADDRKFIALNILSGVM-a...........
A0A0Q4BDZ6_9ARCH/8-124              .............................m-IHDVPYAMSDRDHALWGSLGRD.LRGL..AY..E..AVG.......Lda...nehVMEGL....TIACVPVTAGQSTISGFSESVCAVAE.HLGSRSYVTKRTDVAGFLDAIEAGADIVFMADDEEFVAFNVKAGRA-v...........
A0A1Q6DT49_METT1/8-123              .............................t-VKKVSQKLKKIDSQIRDFSGSS.FNEI..CRgsD..YFD.......Nq......vDPSKK....KTAAVPVTEELGEISGFSETVSEILN.YLGFNSAHVDESDVLGFSKAIKKKPDLVFMADNDQFISYNTKTNSF-v...........
A0A1W2BE48_9FIRM/15-133             ..........................dich----VDEMLSEYDQRLCKRVGQG.LAGI..AA..H..SLG.......Rsae.efagLRQHV....SIGVIPIAYGQGIIHGFSRSVQKIIE.FLGFNAFVTDQNNIAGLAEAAAKGAKIIFLADDDKFVAINVASGKVS............
A0A0F2J7V6_9FIRM/8-124              ........................dvepia------TTLVGYNEDLLRMTGCS.LREL..AA..Q..ASG.......Kei...dylVNRNP....LVAVIPMTCGEGIIEGFVESVASIIS.YLGSRTVITKISDAGGVAEAIQLGAEILFMADDDRFVAINIRTGKVS............
C8VVD4_DESAS/8-126                  ...........................dis---HIPLNLNEYNKKLLKDTGKS.LGGI..AA..Y..AAG.......Ttke.iiynLRQDI....PAAVIPITCGEGIINGFSISVQRIID.FLGFSAFVTDQKDVGGLAEAVEKGAKIIFLADDNRFVAINILTGKVV............
A0A1Q8QIU1_9FIRM/8-124              .............................d-VNEIATSMVDYDTELVRRTGSS.LKGI..AA..N..AVG.......Rel...salYNQQP....QVAVIPMTCGQGIINGFVESVASIIS.YLGFNTVVTESRDAGGVAEAVQNGADILFMADDDRFVALNIKTGKVS............
A0A410PWR4_9FIRM/24-141             .........................ieyml------EGMDEYNRQLKARTDMN.LAEL..IK..T..TFH.......Mkde.afeqAKAVN....KIAVIPITQGEGIIGSFSESVAAILE.SMGFEALVMEHTDIDGIYEASERGCDLLFFADDVRYLALNIKSGKVS............
H5XS84_9FIRM/8-123                  .............................d-IDLIAQQIKEYNEELVRKTGHT.LSEI..AA..H..AIG.......Mhy....tdVPNPG....PVAVLPMTCGQGVIGGFSETVAGILS.FLGMSTFVPAFPDVKGFAETLERKAEIVFMADDDRFIAAHLKTGYCS............
A0A1C3F2W5_9FIRM/8-126              ...........................dil---DMAENLKEYNKQLLNNVGKA.LWEI..AA..H..ANG.......Hrqa.eindLVQFG....PVAVIPVSSGQGIINGFSGSVQKIIE.FLGFPAFVTGGHDVGGLAEAIEKGGKVIFLADDDHFVAINLAKGKVV............
D7E780_METEZ/8-119                  ............................dl--YNVSRQFEKNNDIIKRATGQG.IRDI..CE..S..VYN.......T........RLGNE....KIGIIPITAGNGIIDNFAESLFTITN.YLKLDGFITNHTDVAGYYEAVNQNADILLMADDYVFIAHNLRNGKI-a...........
A0AAE4MJW0_9EURY/8-119              .............................d-LQNMTDALVENDNLVCTLTGLS.LDRL..CA..D..IYK.......T........EKKNE....KIAIIPVTAGCGIIGRFSESLLFTVQ.HFGMDGFITKNTDIAGFYEAVTSGADIILMADDLAFVAYNLKSQKI-a...........
H5XXG9_9FIRM/8-124                  ........................dvaala------AGLEEYNAELVGMTGCS.LREI..AA..H..AAG.......Kgd...redGARKF....SVAVIPMTCGQGIIESFAESVAGIVN.YLGFKTVITENRDVGGVAEAVQNGSEILFMADDDCFIALNLRTGKVS............
A0A0E3L7D7_9EURY/8-119              .............................d-LENIKKQLERADTAVSKVTRLN.VKEV..CK..D..LYG.......T........SPHYE....SVGIVPVTSGNGIIGNFSDSLKVITD.YFKFDSFVTEMPDVSGYYEAVESGAEIILMADDNTFLAHNLTNGKI-g...........
A0A099RU08_9FIRM/8-124              ...........................dvv---EIPTTLEDYDQQLIRKTGCS.LKEL..AA..R..AAGfh..sniE........VNHQA....KVAVVPMSCGQGIIEGFAESVAGIIS.YLGFKAFTTKSWDAGGIAEAIQEGAEVLFMADDERFVAVNVRTAKVS............
A0A0X8V1N8_THEX5/8-124              .............................d-VKDLSENLGALEDFLVKNTGRT.LKKL..AC..E..AVG.......Mwe...yaiDTKEY....TCAVVPVTTGEGIISNFSESVRDICK.WLGFEAFVTKKTDISGFKEALEQKPNIIFMADDVEFLAYNIEAKKAS............
A0A133VJ69_9EURY/43-153             .........................wvrnn--------INTLDTKLKNLIDLG.LEEIcnGE..D..YFG.......K.......gADKEN....KIGVIPISSSDGVIRHFSETVSFILN.YLDFNSEVASEKDVFGLKKSIEGNKDIVFIADDNRFVAIKF------dglmv.......
A0A1W1HAY0_9BACT/8-131              .............................d-IEDIETGLESYDRSLFAKTGCN.LAEI..AM..T..ANSyd...yeKnegyfngkNIKNF....NIKVVPVTAGLGIISTFSETVCAILK.HIGFKASVTKNKDSSGIAEAFEDEADAIMMSDDNRFVGINLNTRKVV............
A0A8T9VQ90_9EURY/10-122             .........................gwvrn-------NIDVIDENLRRFVGLS.FREI..CM..GggFFE.......Td......iHERDK....SVSVVPLTAGEGEIPGFSRAVCDVLG.YVGFDACVVD-GDVAGLTSSVEGDYDGVLLADDEMFVGIDLDS----rcvs........
A0A1H0KHX4_9BACT/2-115              ......................gaqladyd-------------RRLRLATGRG.ILGV..AC..H..SYGvaeekirK........RAEQQ....SCYVIPVTAGQGVISGFSKTVCAILG.FIGCNSVVADSSDTGGIFQAFEAGADIMFMADDFTFAGFNLRRGTVV............
R9T6N8_METII/1-117                  ............................mi--KHVPYASVERDRTLISSIGID.MKGL..AY..E..AVS.......Vip...dsmPLEDF....STAVVPVTSGKGVTPGFTESVCSILQ.HLGMKSFITQRTDIAGLSDALAAKADIVFMADDAEFIALNTHTST--fs..........
A0AAF0S5D8_9ARCH/9-123              ..........................iegv-----PDDKLDLDSRLMKMCGKT.VKQL..AL..E..GAG.......Vdh....dvDFSKV....RVAVVPITSGMGVISGFSKSVDAIVK.RLGMDSYVTAGTDVNGFQQGILDKVDMIMMADDAMFVAYNVHEA---rst.........
A0A0A7LDQ5_9ARCH/8-124              ..............................MVKDIIRSLDSANEMLITLTGMD.TIEL..AC..D..AIG.......Itp...dmiDLDGI....KVGVVPITAGKGTISKFSESVAEIVR.RIGMEPFVTNGTDVNGLAEALSAKADIVFMADDIKFIAVNTKDGRYS............
A0A562GF58_9FIRM/8-124              .............................d-ISKISTMLTNYDSELIRKTGCS.LREI..AA..S..AAN.......Rna...ktiFSPRP....KVAVIPMTCGEGIIPGFAESVASILN.YLSFTAFTTANCDVAGIYEAMSKGANILFTADDNQFVAINLCNGAMV............
A0A1W1YJ27_9FIRM/8-126              .............................d-IDRIIYQMDQYNQELLNKTGHT.LAEI..AA..H..AVGikgvdeaK........LRGLG....PIAVIPMTCGQGVIGGFSETVTGILA.FLGTKAFVTNSSDAKGFAEALERKAVIIFMADDERFIAANLKTGQCS............
D5E9G1_METMS/8-119                  .............................d-LEGLTKQLEYNNNTIKKATGMD.IADI..CK..Q..IYS.......T........TLDGE....KVGIVPITSGNGIISNFSSSLLTITE.YFGLDGDITEHPDVTGYYEAVSSDADIILMADDHIFIAHNMRNGKI-a...........
A0A348AJN7_9FIRM/8-125              ...........................did---TVSARLPAYNETLRRLLGKG.LAEV.aAY..S..QAG.......Spg...dfaVWQDT....PVGVIPVSCGQGVIGGFAHTVKEIIA.FLGFSSFVTARSDVGGLAEAVQRGAQVVFLADDDHFVAIHLAKGKVV............
D9QUB4_ACEAZ/8-124                  .............................q-ISHIPETIDEYNQELKDKTGCG.LVGL..AN..H..ALG.......Tey...etaFLAQK....RAAVVPVTVGEGIIQGFSKSVAAILE.YMGFEILVTNSSDVKGIKEAYQKKADILLMADDDEFIALNLEENKYV............
A0A942J1L1_9FIRM/9-122              .....................lravnlgsf------------DKEVQCKTGRT.ICQL..AA..E..VAG.......Lpe...plpTRRQR....LFAVIPVSAGQGIVKGFVEQVEAVLV.YLGLTVKKIAETDVAGLAQAALAGADIVFCADDSLFMALNLKNGTC-i...........
Q24MJ7_DESHY/8-123                  .............................d-IESILRQMNIYDAELLAKTGYR.LAHI..AA..H..AVG.......Rls....adIPDPG....LIAVVPMTCGLGVISGFAETVAGILG.FLGMRAFVPVSPDVKGFAEALERGAEIIFMADEERFIGVHLKTGQIS............
A0A6B9TA40_9ARCH/8-122              .............................m-IKDVPEDKIDLDTRLMQAAGKT.VKGI..AL..E..AAGlp...edT........DLSGF....KVAVVPITSGLGIISGFSASVDAIVK.RLGMDSHVTQGTDVNGFTEAVREGADIIMMADDNMFIAYNVRE----mre.........
PYLD_METAC/8-119                    .............................d-LENINRQLHEADSTVRRVTGLD.IKGV..CK..D..FYG.......T........TPCCE....KVGIVPVTSGNGIIGNFSESLRAITE.YFGFDSFVTTMPDVSGYYEAVRNGAQIILMADDNTFLAHNLKNGKI-a...........
D5X8E2_THEPJ/8-123                  ...........................dic---HIKASLEKYNRDLIAKTGAT.LGQI..AA..Y..AAE.......Tre....ekVCRNF....KVAVIPLTCGRGIIEGFTQTVASITG.FLGFNSFVTKNTDAGGVAEAVEKGAEILMMADDDKFVAINRVTGRVS............
A0A484F5W1_9EURY/8-119              ............................dl--ANMTDALVENDRLITELTTYS.LDGL..CR..K..IYG.......T........APAKE....KVAIIPITAGGGIIGSFSESLLFTVQ.HFGMDGFITENTDVAGWYEAVTKGADIILMADDLAYIAHNLRNGKI-a...........
A0A1I1Z155_9FIRM/14-126             ...........rgmqgldrhveaasnlslf-------------------DMLCrIMTC..NK..E..EAV.......K........RLKDN....KICVIPITQGQGIIGEFSESIRGILS.FMGANVEVSPKTDVSGMHYAIENRCNIVYFADDERYLAVDLKNF---ksa.........
#=GC seq_cons                       .............................s...tl.pplpphsppLhptTGhs.Ltpl..ut..c..uhG.......p........thpph....plAVlPlTsGpGIIsuFocSVsuIlp.alGhpuhVTppoDVuGltEAlppGA-IlFMADDspFlAhNlcsG+h.............
//