GenomeNet

Database: Pfam
Entry: REV
LinkDB: REV
Original site: REV 
#=GF ID   REV
#=GF AC   PF00424.21
#=GF DE   REV protein (anti-repression trans-activator protein)
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Pfam-B_169 (release 1.0)
#=GF GA   22.00 22.00;
#=GF TC   22.40 22.00;
#=GF NC   21.80 20.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Rev_(HIV)
#=GF DR   INTERPRO; IPR000625;
#=GF DR   SCOP; 484d; fa;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF SQ   35
#=GS REV_HV2UC/1-89           AC Q76631.1
#=GS REV_SIVTN/1-91           AC Q8AIH7.1
#=GS REV_HV1ET/1-93           AC Q75006.1
#=GS REV_HV2BE/1-91           AC P18093.1
#=GS Q9Q6W0_9HIV1/1-93        AC Q9Q6W0.1
#=GS W8EEZ9_9PLVG/1-92        AC W8EEZ9.1
#=GS REV_HV1YB/1-96           AC Q9IDV4.2
#=GS REV_HV1EL/1-93           AC P04621.1
#=GS REV_HV193/1-92           AC O70890.1
#=GS REV_SIVMB/1-93           AC Q1A263.1
#=GS A0A1B4WRK7_SIV/5-86      AC A0A1B4WRK7.1
#=GS REV_HV1AN/1-89           AC P0C1L4.1
#=GS Q77Y21_9PLVG/1-93        AC Q77Y21.1
#=GS A0A6A5LT68_LUPAL/34-102  AC A0A6A5LT68.1
#=GS P89908_SIVTA/2-95        AC P89908.1
#=GS REV_HV1Y2/1-93           AC P35960.1
#=GS REV_HV1A2/1-92           AC P04623.1
#=GS A0A2A9PFF7_9HYPO/39-104  AC A0A2A9PFF7.1
#=GS REV_HV1MV/1-95           AC P0C1L3.1
#=GS Q87112_SIVSA/2-84        AC Q87112.1
#=GS REV_HV1H2/1-93           AC P04618.1
#=GS REV_HV1H2/1-93           DR PDB; 7JYA D; 15-24;
#=GS REV_HV1H2/1-93           DR PDB; 7JYA E; 17-24;
#=GS REV_HV1H2/1-93           DR PDB; 7JYA F; 19-24;
#=GS REV_HV1H2/1-93           DR PDB; 6HIP C; 41-49;
#=GS REV_HV1RH/1-93           AC P05870.1
#=GS REV_SIVCZ/1-96           AC P17280.1
#=GS REV_HV2RO/1-91           AC P04615.1
#=GS REV_HV1B9/1-93           AC Q73371.2
#=GS REV_SIVEK/1-93           AC Q1A245.1
#=GS REV_HV190/1-93           AC O70900.1
#=GS REV_HV192/1-93           AC O12162.1
#=GS REV_HV1MA/1-94           AC P04622.1
#=GS REV_SIVSP/1-89           AC P19502.1
#=GS REV_HV1BR/1-93           AC P04620.1
#=GS REV_HV1B1/1-93           AC P04616.1
#=GS REV_HV1B1/1-93           DR PDB; 6CF2 F; 10-66;
#=GS REV_HV1B1/1-93           DR PDB; 6BSY B; 11-65;
#=GS REV_HV1B1/1-93           DR PDB; 2X7L O; 9-65;
#=GS REV_HV1B1/1-93           DR PDB; 5DHZ M; 5-65;
#=GS REV_HV1B1/1-93           DR PDB; 5DHV N; 8-65;
#=GS REV_HV1B1/1-93           DR PDB; 5DHX M; 5-65;
#=GS REV_HV1B1/1-93           DR PDB; 2X7L N; 9-65;
#=GS REV_HV1B1/1-93           DR PDB; 5DHX C; 5-65;
#=GS REV_HV1B1/1-93           DR PDB; 5DHY C; 5-65;
#=GS REV_HV1B1/1-93           DR PDB; 2X7L M; 9-65;
#=GS REV_HV1B1/1-93           DR PDB; 5DHV M; 5-65;
#=GS REV_HV1B1/1-93           DR PDB; 5DHY M; 5-65;
#=GS REV_HV1B1/1-93           DR PDB; 2X7L R; 9-65;
#=GS REV_HV1B1/1-93           DR PDB; 2X7L P; 9-65;
#=GS REV_HV1B1/1-93           DR PDB; 2X7L Q; 9-65;
#=GS REV_HV1B1/1-93           DR PDB; 6BSY A; 8-65;
#=GS Q9YX51_9HIV1/1-94        AC Q9YX51.1
#=GS Q72501_9HIV1/1-93        AC Q72501.1
#=GS REV_HV1YF/1-93           AC O91084.2
REV_HV2UC/1-89                      mttr--------.EKDLQKGLRLLHLLHQTNPYPQ.T.PGT.ASQRRNRRRRW.....KRRGLQILALADRIRSLS..-DSPTEEPLDLAVQRL....QELTVEDLPNPPT--st................
REV_SIVTN/1-91                      ....MAGREE--.DANLLYTVRIIKILYDSNPYPS.G.AGS.RTARRNRRRRW.....RQRQHQVDALASRILQYR..LGGP-QEPPHLDIPDL....SKLHLDPLDQPA---ste...............
REV_HV1ET/1-93                      ....MAGRSGDS.DEELLKAVRIIKILYQSNPYPT.P.EGT.RQARRNRRRRW.....RARQRQIHTLSERILSNF..LGRP-AEPVPLQLPPL....ERLNLDCSEDSGT--sg................
REV_HV2BE/1-91                      ....MSERAD--.EEGLQGKLRLLRLLHQTNPYPQ.G.PGT.ASQRRNRRRRR.....RRQWLRLVALANKLCAVP..-DPPTDSPLDRAIQHL....QRLTIQELPDPPTDL..................
Q9Q6W0_9HIV1/1-93                   ....MAGRSGDS.DEELLKTIRLIKFLYQSNPPPS.P.EGT.RQARRNRRRRW.....RERQRHIHSISEQILSTY..LGRP-EEPVLLHLPPL....ERLTLDCSEDCGT--sg................
W8EEZ9_9PLVG/1-92                   ....MAGRSGGT.DEDLLRAVRIIKILYQ-NPPPS.S.EGT.RQARKNRRRRW.....RARQRQIRALSDRILIPF..LGGS-TEPVPLQLPPL....ERLTLDCSXDCGT--sg................
REV_HV1YB/1-96                      ....MAGRSGVN.DEDLLKAVKIIKILYQSNPYPD.SsQGT.RQARRNRRRRW.....RARQRQIRAISERILGAY..LGGP-QEPVDLPLPPL....GRLTLDHKEDSG---dpgte.............
REV_HV1EL/1-93                      ....MAGRSGDS.DEDLLKAVRLIKFLYQSNPPPS.P.EGT.RQARRNRRRRW.....RARQRQIREIAERILGTY..LGRP-AEPVPLQLPPL....ERLNLNCSEDCRT--sg................
REV_HV193/1-92                      ....MAGRSGDS.DQELLKAVRYIKILYQSNPYPK.P.EGT.RQARRNRRRRW.....RARQRQIREISDRILSSC..LGRP-AEPVPLQLPPL....ERLHINCSEDCG---qg................
REV_SIVMB/1-93                      ....MAGGSGNS.DEELLRAVRIIKILYQSNPYPS.P.EGS.RQARRNRRRRW.....RARQRQINSLSERILSTC..LERP-TGPVSLPLPPI....ERLTLDSAEDIGT--gg................
A0A1B4WRK7_SIV/5-86                 peer--------.--------RLLRLLQWLNQTSK.V.EGT.ARQRRRRRRRW.....REIQDQIRHLAERIWNTR..QEDQLVQGIDQLVINA....QHLAIQSLPDPPN--qa................
REV_HV1AN/1-89                      ....MAGRSE--.DDQLLQAIQIIKILYQSNPQPS.P.RGS.RNARKNRRRRW.....RRRQAQVDTLAARVLATV..VHGPQNN-NIVDLPPL....EQLSIRD--------pegdql............
Q77Y21_9PLVG/1-93                   ....MAGRSGDS.DEELIRTVRLIKLLYQSNPPPN.P.EGT.RQARRNRRRRW.....RERQRQIHSISERILGTY..LGRS-AEPVPLQLPPL....ERLTLDCNEDCGT--sg................
A0A6A5LT68_LUPAL/34-102             fevs--------.-------------LHSAVAKPT.P.QGI.RDRRRRRRRRWqgvrlRKHEFAIIAIQESVLSRP..----------------....---------------tpngneeefenlivlnki
P89908_SIVTA/2-95                   .slg--------.SEDLRRIIQIIRILYHSNQYPP.G.EGT.ARQRRRRRQRF.....QQQQRQVAALSERIFIAQqrRDPSGGESLAAAFDQLvldnQQLVIETLPDPPQ--e.................
REV_HV1Y2/1-93                      ....MAGRSGDS.DEDLLRTVRLIKVLYQSNPPPS.S.EGT.RQARRNRRRRW.....RERQRQIRSISGWLLSNY..LGRP-TEPVPFQLPPL....ERLTLDCNEDCGT--sg................
REV_HV1A2/1-92                      ....MAGRSGDS.DEELLRTVRLIKLLYQSNPPPS.P.EGT.RQARRNRRRRW.....RERQRQIRSISGWILSTY..LGRS-AEPVPLQLPPL....ERLTLDCSEDCGN--s.................
A0A2A9PFF7_9HYPO/39-104             .hmg--------.--------------YGSNSTSS.Q.DQA.LTHRRRRRRRR.....RRRRRRLHTIALPDYTLA..-PASSASPTPP-----....---------------fsspsmqltlpp......
REV_HV1MV/1-95                      ....MAGRSE-E.DQQLLQAIQIIKILYQSNPCPT.P.AGS.RNARKNRRRRW.....RRRQAQVDSLATRILATV..VHGSQDNNL-VDLPPL....EQLNIRD--------peadrlpgtgt.......
Q87112_SIVSA/2-84                   .slg--------.QEELLRRFRIIKFLYTTNPYPP.G.QGT.ARQRRRARQRW.....AKQRQQVIHLAERILETP..-----VSQIDHLAQEF....DQLVLDNLQQPPS--l.................
REV_HV1H2/1-93                      ....MAGRSGDS.DEELIRTVRLIKLLYQSNPPPN.P.EGT.RQARRNRRRRW.....RERQRQIHSISERILGTY..LGRS-AEPVPLQLPPL....ERLTLDCNEDCGT--sg................
#=GR REV_HV1H2/1-93           SS    ....XXXXXXXX.XXXXXXXXXXXXXXXXXXXXXX.X.XXX.XXXXXX--SST.....TTT-XXXXXXXXXXXXXX..XXXX-XXXXXXXXXXX....XXXXXXXXXXXXX--XX................
REV_HV1RH/1-93                      ....MAGRRGDS.DEDLLKAVRLIKSLYQSNPPPS.P.EGT.RQARRNRRRRW.....RERQRQIRRCSEWILDTY..LGRS-VDPVQLQLPPL....ERLTLDSSEDCGT--sg................
REV_SIVCZ/1-96                      ....MAGRSEPQdDARLLQAVKIIKILYQSNPYPS.P.EGT.RKARRNRRRRW.....RARQKQISEISGRVLATY..LGRP-PKPGDLELPEL....DKLSLQCVET-----tqdvgts...........
REV_HV2RO/1-91                      ....MNERAD--.EEGLQRKLRLIRLLHQTNPYPQ.G.PGT.ASQRRNRRRRW.....KQRWRQILALADSIYTFP..-DPPADSPLDQTIQHL....QGLTIQELPDPPTHL..................
REV_HV1B9/1-93                      ....MAGRSGDS.DEDLLKTVRLIKFLYQSNPPPS.L.EGT.RQARRNRRRRW.....RERQRQIRSISERILGTF..LGRF-EEPVPLPLPPL....EKLTLDCNEDCGT--sg................
REV_SIVEK/1-93                      ....MAGRSGVN.DEELLRAIRVIKILYQSNPYPN.D.SGT.RQARKNRRRRW.....RARQRQIRALSERILSSC..VGGL-QEPSTLPLPPL....DRLSLNPEEDLGT--se................
REV_HV190/1-93                      ....MAGRSGAS.DTELLQVCKIIKILYQSNPCPE.P.TGT.RQARRNRRRRW.....RARQRQIREISERILTSC..LGRP-PEPVTLQLPPL....ERLTLNCSEDCGT--sg................
REV_HV192/1-93                      ....MAGRSGDS.DEALLQAVRIIKILYQSNPYPK.P.EGT.RQARRNRRRRW.....RARQRQIHSISERILSTC..VGRP-AEPVPFQLPPI....ERLNINCSESGGT--sg................
REV_HV1MA/1-94                      ....MAGRSGDS.DEDLLRAIRLIKILYQSNPPPN.T.EGTtRQARRNRRRRW.....RARQRQINSIGERILSTY..LGRP-EEPVPLQLPPL....ERLTLNCNEDCGT--sg................
REV_SIVSP/1-89                      .mss-------N.EEELRRRLRLIHLLHQTNPYPD.G.PGT.ANQRRRRRRRW.....RQRWQQILALADRIYSFP..-DPPVDTPLDLAIQQL....QRLAIEELPNPPA--sa................
REV_HV1BR/1-93                      ....MAGRSGDS.DEDLLKAVRLIKFLYQSNPPPN.P.EGT.RQARRNRRRRW.....RERQRQIHSISERILSTY..LGRS-AEPVPLQLPPL....ERLTLDCNEDCGT--sg................
REV_HV1B1/1-93                      ....MAGRSGDS.DEDLLKAVRLIKFLYQSNPPPN.P.EGT.RQARRNRRRRW.....RERQRQIHSISERILSTY..LGRS-AEPVPLQLPPL....ERLTLDCNEDCGT--sg................
#=GR REV_HV1B1/1-93           SS    ....XXXXXHHH.HHHHHHHHHHHHHHHHTS-S--.S.-ST.TTHHHHHHHHH.....HHHHHHHHHHHHHHHHTT..T-XX-XXXXXXXXXXX....XXXXXXXXXXXXX--XX................
Q9YX51_9HIV1/1-94                   ....MAGRSGNI.DEDLFKAARAIKILYQSNPYPNnP.TGT.RQARRNRRRRW.....RARQKQIHSLSERILATY..LGRP-AEPVPLQLPPL....EKLTLNCSEDCGT--sg................
Q72501_9HIV1/1-93                   ....MAGRSGDS.DEELIRTVRLIKLLYQSNPPPN.P.EGT.RQARRNRRRRW.....RERQRQIHSISERILSTY..LGRS-AEPVPLQLPPL....ERLTLDCNEDCGT--sg................
REV_HV1YF/1-93                      ....MAGRSGVN.DEELLRAVRVIKILYQSNPYPN.S.KGT.RQARRNRRRRW.....RARQRQIRAISERILSSC..LGGP-PEPVDLPLPPL....DRLTLDTEEDSGT--pg................
#=GC SS_cons                        ....XXXXXHHH.HHHHHHHHHHHHHHHHTS-S--.S.-ST.TTHHHHHHCCC.....CCCHHHHHHHHHHHHHTT..T-XX-XXXXXXXXXXX....XXXXXXXXXXXXX--XX................
#=GC seq_cons                       ....MAGRSGss.DE-LL+slRlIKlLYQSNPhPs.s.-GT.RQARRNRRRRW.....RpRQRQI+ulSERILuoh..LGps.sEPVsLpLPPL....ERLoLcspEDsGT..Su................
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