#=GF ID   RE_CfrBI
#=GF AC   PF09516.16
#=GF DE   CfrBI restriction endonuclease
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Bateman A
#=GF GA   25.00 25.00;
#=GF TC   29.50 29.30;
#=GF NC   24.60 24.50;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 81514348 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0236
#=GF RN   [1]
#=GF RM   8335262
#=GF RT   Cloning and sequences of the genes encoding the CfrBI
#=GF RT   restriction-modification system from Citrobacter freundii. 
#=GF RA   Zakharova MV, Kravetz AN, Beletzkaja IV, Repyk AV, Solonin AS; 
#=GF RL   Gene. 1993;129:77-81.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR019042;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family includes the CfrBI (recognises and cleaves C^CWWGG)
#=GF CC   restriction endonuclease.
#=GF SQ   35
#=GS A0A1I2KAN8_9BACT/5-253    AC A0A1I2KAN8.1
#=GS E7G369_9HELI/5-252        AC E7G369.1
#=GS A0A0B7I144_9FLAO/5-250    AC A0A0B7I144.1
#=GS A0A1T5P8J2_9BACT/38-289   AC A0A1T5P8J2.1
#=GS A0A1H4F236_9BACT/24-252   AC A0A1H4F236.1
#=GS A0A6V8PEE8_9ACTN/26-252   AC A0A6V8PEE8.1
#=GS A0A930T462_9CHRO/5-245    AC A0A930T462.1
#=GS A0A1F2P9M5_9EURY/2-242    AC A0A1F2P9M5.1
#=GS A0A268TFF8_9HELI/5-249    AC A0A268TFF8.1
#=GS A0A3D9L3L4_MARFU/116-253  AC A0A3D9L3L4.1
#=GS A0A377PV82_9HELI/1-154    AC A0A377PV82.1
#=GS A0A3D9L3L4_MARFU/26-119   AC A0A3D9L3L4.1
#=GS A0A2N4S902_9BACT/5-249    AC A0A2N4S902.1
#=GS A0A1D2R8X0_9ARCH/7-256    AC A0A1D2R8X0.1
#=GS A0A0S7BS10_9CHLR/28-282   AC A0A0S7BS10.1
#=GS A0A6L9EV26_9FLAO/30-276   AC A0A6L9EV26.1
#=GS A0A930UDA5_9FLAO/6-256    AC A0A930UDA5.1
#=GS M4YLA5_THEXX/24-238       AC M4YLA5.1
#=GS A0A180FR23_9BACT/5-245    AC A0A180FR23.1
#=GS A0A916Z1Q6_9BACT/30-275   AC A0A916Z1Q6.1
#=GS A0A6S4QFD5_UNCSP/5-252    AC A0A6S4QFD5.1
#=GS A0A2W7T894_9BACT/5-246    AC A0A2W7T894.1
#=GS A0A180FHW5_9BACT/5-250    AC A0A180FHW5.1
#=GS A0A7C8LSY4_9FIRM/27-273   AC A0A7C8LSY4.1
#=GS V2QEN6_9BACT/6-252        AC V2QEN6.1
#=GS A0A8F1WK42_9BACT/5-251    AC A0A8F1WK42.1
#=GS A0A0F2IVS8_9BACT/7-253    AC A0A0F2IVS8.1
#=GS A0A2M8S3A0_9PAST/5-251    AC A0A2M8S3A0.1
#=GS A0A238HF71_9NEIS/5-252    AC A0A238HF71.1
#=GS A0A2H5XEU3_UNCXX/35-199   AC A0A2H5XEU3.1
#=GS A0A1E5IID0_ENDTX/5-254    AC A0A1E5IID0.1
#=GS B5YIR7_THEYD/2-251        AC B5YIR7.1
#=GS A0A2N3HXD0_9BACT/5-246    AC A0A2N3HXD0.1
#=GS A0A0A2EPE0_9PORP/5-250    AC A0A0A2EPE0.1
#=GS A0A3A9CDM4_UNCXX/28-160   AC A0A3A9CDM4.1
A0A1I2KAN8_9BACT/5-253               ....................eqv---TKNIISRLIKGQDYRIEVVALINAQFLQFAMD.FFEKIV..QAK..L..R..--..-..---.-N-.--.KD.VIDW...-.YKKEFLNPKL...SSeeiAINSGLNKKTITNMFN-SATKEIVI..DASNE.HYEIL.yNSILQLIE..NQSEID...LTLTIK..FRGV.--SVELNINESLIVINTLAVKRAALRGGLWSTAGKKVEKPLMQTLCMLFDVP..KENY..AI..HlkgAKA...K....Q...E....DELD......FEREIDFYLIS.N.-GQNH.KCEVKLMGKGNPESADAVIARD..S..KVFIADKLSDLN-k..........................................
E7G369_9HELI/5-252                   ....................evm---VEQIINKLLRGEDYRDEIINAINVEFLDFALF.FFKQIL..EAK..M..Q..DE..AlyLAW.YKK.HF.IS.DPDI...T.PKE-------...-A...AIYAGINEKTIRNIYG-CGTKEVIL..DVAQN.NMDYL..ENLLHAL-..GESENI...G-IHLK..ITHK.SISVELDLNESLVVINALATKKIALRGGAWSSVGKKVEKPLLLALCQKCGVS..EGFY..SA..K...TFC...-....K...D....KNLA......YDREVDFKLYNaD.KSQEY.RVEVKLMGKGNPESADAVMARE..S..HIFVADTLSD---qnk........................................
A0A0B7I144_9FLAO/5-250               .....................dq--IVKNIITRVIKSEDYRIEIVNLINAEFLQFSVD.FFKKIV..TAK..L..N..--..-..---.SED.IT.ID.W---...-.YKRYFMSEGLsseDI...AINSGLNKKTISNMYG-SATRTIVI..EASNE.HFESL..YQSIQTLVeiEKEIDL...V-LTIK..LKG-.-VSVDLNVSESLVVINTLAVKRAALRGGLWSTAGKSVEKYLMLTLCKLYQVP..ESNY..DA..K...HF-...V....K...D....KGKK......VDREIDFYLLE.R.DNKYL.-CEVKLMGKGNPESADAIIARS..T..NIFVADTLSQ---qnk........................................
A0A1T5P8J2_9BACT/38-289              ......................v-EAVKQAVFSVMMGENLRT-QTEPISRMRIAQVSG.AIIAMI..---..A..K..GY.lT..IDN.FQR.EL.SR.LAIKelaS.AKKNDNEKVW...PA...QWLIGITGKSFQNVLRGN--REALI..EYIAD.FEKAI..KDSAEHCK..QQYGDY...-KMDLHftMNGI.DNKVALDWEGITRLTTAIGSQTLTLRGSDKSIYGKLFERLILGSILTLLGFK..RVDK..NS..D...KKE...R....K...EifwlSDSS......ANRESDATVVI.T.PGHVA.RFDIGFIGPGNSEISKDKLSR-..-..-------------fdrdiev....................................
A0A1H4F236_9BACT/24-252              .....................pa--SLRMLTYHLLRGQNYRL-VTEKNTKDKLLLTYV.WLSDIV..NDA..K..N..EY..G..ENW.QTE.LV.SD.LFSI...-.-RSRTPEQKN...LL...YWLIGLTAKTSVNLGV---------..-----.STRDI..PSVMTDLL..AHVKSL...F-DQIG..RQNQ.--------IDDTWLLLMAGSATLNIRGSEKSKIGKVLEKVMIRSILSILGLV..ENVN..FW..I...NID...-....R...D....LEV-......-DREADAEI-A.T.NRGRI.RVEVGLISSGNQEVTEDKISRV..GrnGIILFDKV-----gqrtr......................................
A0A6V8PEE8_9ACTN/26-252              .....................pa--SLRELVLHLLLGRNYRV-ITEQNTKGRLLITYA.WLIELY..DRF..R..R..EY..G..RNW.REG.LL.SR.LVEL...-.-DRPSSEEKN...LM...YWLVGLTKKTAQNLDI---------..-----.PLEEL..PDFLSETI..RYCNEL...F-TADD..YAHS.--------QEQAWLLLMAGAATLNIRGSQKSKVGKAIERVFLSAALSLLGLR..SERD..FW..I...GVP...-....S...D....IEV-......-ARETDGEV-E.T.KRGRI.RIDIGLIAQGNPEVIT------..-..-----DKVNRVG-rqgvvifdkigth..............................
A0A930T462_9CHRO/5-245               ......................d-QVIKNIIKRLIKGQDYRIEVIALINAEFLQFAIE.FFKQIV..DAK..L..K..NK..D..LT-.-QD.WY.KNyFLDT...-.--KLTSKE--...-I...AINSGLNTKTITNMYN-SASKQIVI..NASNE.HYDVL..YESISNLI..ENENEI...D-LTLT..IKFR.GVSVDLNINESLIVINTLAVKRAALRGGLWSTAGKKVEKYLMASLCYLFDVP..LVHF..DQ..T...NIP...-....-...-....ESM-......--REVDFYLIN.N.EN-YY.RCEVKLMGKGNPESADAIFARE..T..NIFVADKLSDLN-k..........................................
A0A1F2P9M5_9EURY/2-242               .......................KKLISKIVHSILTGEDYRTYVLATINKRFIDKVQE.LTTEIF..EYK..R..K..--..-..---.GDV.WL.EK.LLDD...T.YEKKGKENKF...KL...LWFGGLNDKTVKNMTGGTSKKEVCL..DLGKK.NIEAF..RLLLSEI-..ESSENL...YQIRII..IKKD.TEQVELDEIESIIFVNTISAMKLTIQGGAWSEVGKQTEKSLLFTIFQLLKIP..EEDY..VL..I...FDE...M....K...K....KDLV......GNREIDAIIFN.R.DKEPL.TVELKLLGIGNPEIGDEALARK..V..DLFL---------...........................................
A0A268TFF8_9HELI/5-249               ......................n-QVIKNIVKRVIKGQDYRIEVVNLINTDFLQFVID.FFKKII..KVK..L..E..--..-..---.-NK.DV.VN.WYKK...E.FLKNTLPPD-...EI...ALHAGLNMKTIHNMYG-SSAKEIVI..DAAYE.HYDSL..YEAISGFI..DNNEDL...T-LMLT..LKFN.GVCVDLTINETLLVINTLAVKRAALRGGAWSAVGKTAEKILMKTICELYKIP..TNNY..EE..K...FVR...D....S...A....KKV-......-SREVDFYLKD.N.EGKKY.LCEVKLMGRGNPESADVIFARK..S..HIFIADTLSQ---qnk........................................
A0A3D9L3L4_MARFU/116-253             ....kndyveivretighfnelf-----------------------------------.------..---..-..-..--..-..---.---.--.--.----...-.----------...--...-------------------------..-----.-----..--------..------...------..----.-DRIDIDFKNDAWLLLMAGSATLSIRGSQKSKVGKQVERIFLKAILTILGFE..LDNN..FW..M...NVE...-....R...D....LEV-......-EREADAEV-Q.S.RRGRI.RIEVGLIAQGNQEVVEDKIARVgrH..GIILFDKL-----gnksr......................................
A0A377PV82_9HELI/1-154               .....................ma-----------------------------------.------..---..-..-..--..-..---.---.--.--.----...-.----------...--...-------------------------..---NA.NIDYL..ESLLVSLG..EANESI...G-ISIK..ISYK.EISVELNLNESLLVINALATKKIALRGGAWSSIGKRVEKPLMLALCKKCRVK..K-DY..IN..S...EIF...K....K...N....GELD......FDREVDFRLYNfD.KSKEY.RIEVKLMGKGNPESADAVIARD..T..NIFIADTLS----lqnk.......................................
A0A3D9L3L4_MARFU/26-119              .....................pq--ALRDMVYHILMGRNYRL-LTEPNTKGRLFATFF.WLSKVQ..ESA..I..D..NY..G..DDW.IER.LT.ED.LVST...-.-DKKPEELKN...LL...LWILGLTNKTSVNL-----------..-----.-----..--------..------...------..----.----------------------------------------------------..----..--..-...---...-....-...-....----......-----------.-.-----.----------------------..-..-------------gldkndy....................................
A0A2N4S902_9BACT/5-249               ....................eqv---AKNIIRKLLKGEDYRIEVVTLINAEFLQFAID.FFKKIV..EAKlqS..K..DI..T..VDWyKEA.FL.NP.NLPA...-.-KE-------...-I...AINSGLNKKTIHNMFN-SSTKEIII..DAANE.HYDVL..YESIKNLV..ETEHEL...D-LTLT..IKFK.GVSVDLSVSESLIVINTLAVKRAELRGGLWSTAGKRVEHPLMLTLCKLYSVD..ESNY..KA..I...FKK...D....K...N....KGF-......-DREVDFYLIK.D.DREYL.-CEVKLMGRGNPESADAVIARA..T..NVFVADKLS----iqnk.......................................
A0A1D2R8X0_9ARCH/7-256               .......................KEVTKNIIVKLIKGEDYRIEIVTLINTDFLQYVVD.FFKKIV..DAK..L..K..SK..D..ITV.-DW.YK.QE.FLDD...-.--RLSSEE--...-I...AIHSGLNKKTISNMYN-SARKDIVI..EASNE.HYEQL..YNAIQKL-..VDEEDE...LNITLT..IKFK.GVSVDLNVSESLIVINTLAVKRSALRGGLWSTAGKRVEGPLMITLCKLFGVD..AANY..-K..V...KLK...G....RsevK....TDTG......FEREVDFYLIG.H.SEEEY.KCEVKLMGKGNPESADAVIARD..S..KVFVADKLSD---tnk........................................
A0A0S7BS10_9CHLR/28-282              ...................veta----RQVILAVLRGENIRT-QTEPLTRRRVAIATG.AMVYLF..AKG..W..A..EI..D..-NF.TEN.LS.AF.ALEQ...MdNTPQSKKDTF..wPA...QWLIGLTGKSIQNVLRSNPELRQSYiqDFENA.VEEAA..RRCEEDFG..EISMSL...G-YVVD..GELR.QSVSALNWKDLTRLTTAIGATTLTIRGSEKSTYGKLFERLIMGSVLTILGFE..HVEN..SQ..SpkiERV...F....W...L....SDSS......DVRECDATI-R.L.RPGKLaRFDIGFIGKGNPEIMKDKLTRY..A..N------------eveqng.....................................
A0A6L9EV26_9FLAO/30-276              ......................d-EIIKDVIISVFSGGNIRS-LTEPLTRRRITLSSA.SLLITF..LRS..T..K..-N..V..EGF.PEN.MN.EL.ISKE...L.TTNISKEKKI...YL...QWMLGLTGKSIQNVLRGNDSTSLAS..YLNDL.D-NTL..KNTIDQAR..EDFGNI...K-SNFY..LEKS.DDNILLNWPSLLQLFIAIGTQTLAIRGSEKSMYGKLFEKLILGSLLRVLGFK.lIDPN..TS..T...ESN...MvfwlS...Q....RG--......SKRESDATLLL.K.PGVGA.RFDIGFIGPGNTEISLDKVSR-..-..-------------fereme.....................................
A0A930UDA5_9FLAO/6-256               .....................tv--SLKNVLNKLYEGEDYRGEVISLIQDNFIAYSLD.FLKRVMlaKIE..N..K..DI..T..VDW.YEK.EF.IQ.NEDL...-.-KKD------...EI...AINSGMNMKTISNKYK-TTKKDIVI..SASND.QYDDL..KRAIDELI..DVEKDL...D-LTLT..IKYN.KASVDLTLNETLIVINTLAVKRAAIRAGAWSSIGKNIEKPLMKSLCILYGVP..EKNYeiIY..K...KAD...Y....S...K....NEDI......YSREIDFYLVD.N.TEKSL.LCEVKLMGKGNPEVADAVIARK..T..NLFVADTLSET--nk.........................................
M4YLA5_THEXX/24-238                  .......................ADSLKKLTKHLLCGGNYRA-ITEFNTKCKIALTDL.WLSDVV..EVA..R..K..EY..G..LAW.KEK.ML.AA.LLDK...-.-KKKTTEEKY...LQ...YWLLGLTQKTFNNIDG---------..-----.NTKEL..PSLLSELE..EQLTDT...L-TSIK..REKE.--------LDNVWIMMMCGSAALTIRGSDKSKNGKWVERVLLKSMLTLLGFT..ENKN..FW..V...DLQ...-....R...D....NEV-......-ERETDAEV-E.T.KRGRI.RIELGLIASGNQEV--------..-..---IEDKINRVG-p..........................................
A0A180FR23_9BACT/5-245               .....................dq--VVKNIIKRLIKGQDYRIEVVALINVEFLQFTID.FFKKVI..EAK..L..S..NQ..DvtIDWyKQT.FL.NR.NLSS...-.------DE--...-I...AINSGLNKKTITNMYN-SASKEIVI..DASNE.HYDIL..YQSISNLI..ESQPDI...D-LTLT..IKFR.GVSVELNINESLIVINTLAVKRSALRGGLWSTAGKRVEKYLMATLCKVFHVP..FEHF..DQ..S...KIP...-....-...-....---A......SMREVDFYLIN.G.D-TYS.RCEVKLMGRGNPESADAIFARE..S..NVFVADKLSDLN-k..........................................
A0A916Z1Q6_9BACT/30-275              ......................e-EVVKNVVSSVLCGENVRS-LTESLTRRRLMLSNAaMLVTFL..KAS..N..Q.iES..L..VGK.SAK.MI.AE.ELAT...-.-KRLSKEKKL...YL...TWLAGLTEKSIQNVLRGNEQEE---..--LKQ.YLEEL..GKLLKESA..QKADSSfgnLSGTLK..LGKE.ENSISWESI--MFLFTAIGAQTLAIRGSEKSMYGKLFEKFILGSVLSILGFQriDPKE.sTK..S...DKVf.wM....S...Q....RE--......NKRESDATLLL.K.AGIGV.RFDIGFIGPGNSEISLDKVSR-..-..-------------fereme.....................................
A0A6S4QFD5_UNCSP/5-252               .....................dh--VIKDIIKKPLNSDDYRIEIINLINSEFLRFSIG.FFKEIF..AAKleN..K..DI..S..VDW.YKKtFL.NS.DLSA...-.---------Q...EI...AINAGLNKKTIHNMFN-SSKKEIVL..DVANE.HYTTL..HESIKNLV..DTQHDI...E-LTLT..IKFN.KVSVDLNISESLIVINTLAVKRSELRGGLWSTAGKRVEKPLMETICRLYNVP..AENY..DS..S...KIKrnaS....A...K....NSI-......-QREVDFYLIK.G.-DNSY.KCEVKLMGKGNPESADAAIARD..S..KIFIADKLSD---tnk........................................
A0A2W7T894_9BACT/5-246               .....................td--AKKNIIKKVISNQDYRDEVLVIIDEIFLDYCIS.FFKQVV..YAK..I..D..--..A..LGE.KSD.WY.KK.VFLN...-.----PDLPKE...QI...AINSGLNMKSITNAFN-SSKKEVVI..QASYD.NYNRL..QKTINDLV..SNGNNF...E-IKLS..IKFK.DVAVDLTVAESLIVINTIAVKRAEIRGGMWSAVGKQVEKPLMTTLCMLFNVP..FEYH..-A..Q...DGN...-....-...P....DSF-......--REVDFYVLS.K.DGKKL.RTEVKLMGKGNPESADAIFARQ..P..AIFLADKLSD---knk........................................
A0A180FHW5_9BACT/5-250               ....................dqv---TKNIVCKLLKSEDYRIEIVTLINAEFLQFAID.FFKKII..DAK..LqsK..DI..T..IDW.YKK.--.-A.FLNP...-.-KLSAKE---...-I...AINSGLNKKTIHNMFN-SSTKEIII..DASNE.HYDLL..YKSIQNL-..VDTEDE...LELTLT..IKFK.GVSVDLNVSESLIVINTLAVKRAELRGGLWSTAGKKVEKPLMKSLCKLYQVP..ENNY..DA..S...HFV..kN....K...R....KKV-......-DREIDFYLLN.N.DKQYL.-CEVKLMGKGNPESADAIIARG..T..NVFIADTLSQ---qnk........................................
A0A7C8LSY4_9FIRM/27-273              ......................v-DGMKDIIRKVLIGGNVRD-ITEFITQRRLIISYA.AMIDLF..VNK..L..I..-S..K..TNK.IQD.YA.DY.VSDD...L.KLARSNDQKI...LD...LWLMGLTKKGLDNIVRD----ETNL..A-SYK.NSFAVsaTETISDIQ..ERFGDL...S-GKLN..LNGV.--EIDLNWNIISLLSIALGAQTLSIRGSAKSMNGKLFEKLILGSLLTIMGFR..YCST..PP..T...NMQ...K....T...D....KLFWlsnmdeNERETDGTM-V.Y.NGIAI.SIDIGFIGKGNPEISLDKVT--..-..-------------rfnrykqia..................................
V2QEN6_9BACT/6-252                   ....................eii---IKQTVDKLLKGEDYRSIVVSKINADFLQFAID.FFKDII..KAK..C..DstDI..S..LNWyKQN.FI.NN.DLIS...-.-----TDN--...-I...AIYAGINKKTIHNIKG-SATKEVVL..DFASE.NFEYL..SLMIKELE..DEAFSG...LDVVIK..LSYN.GVSVELSLSESLIVINALATKKIAIRGGAWSSIGKKCEKPLMLKLCELCGVP..ME-N..IN..S...DIF...-....K...K....NTL-......FDREVDFKIKS.N.SGVWN.RCEVKLMGKGNPESADAIFARE..S..KIFIADTLSKMNK...........................................
A0A8F1WK42_9BACT/5-251               ......................e-EVAKNIIKKLLKGDDYRIEIVTLINAEFLQFAID.FFKNIV..DAK..L..N..NM..D..ITV.--D.WYkRA.FLNP...-.-DLPAKE---...-I...AINSGLNKKTIHNMFN-SSTKEIVI..NASNE.HYDLL..YESIRNVV..DNEHDL...E-LTLT..IKFK.GVSVDLNVSESLIVVNTLAVKRAELRGGLWSAAGKRVEKPLMQTLCKLYGVP..EQNY..ALriK...GKE...I....E...D....DDF-......-NREIYFYLVY.G.KN-QY.KCEVKLMGRANPESADAVIARD..S..KVFVADKLSD---tnk........................................
A0A0F2IVS8_9BACT/7-253               iaingnmitvefdtavkqnevay----------------------------VVTKDGR.LKSEVV..RIK..A..N..--..T..AKL.KNQ.--.NI.TVDW...-.YKKEFLNPKL...PAkdiAINAGLNKKTIHNMFN-SSTKEIVI..DASTE.HYKAL..YDTIGKLV..DAQQDI...E-LTLT..IKFK.GVSVELNISESLIVINTLAVKRSELRGGLWSAAGKRVEKLLMLTLCKLYGVS..EKNY..AI..E...IKG...K....A...G....DHID......FTREIDFYL-I.S.GNNNY.KCEVKLMGRGNPESADAVIARD..S..KVFIADKLSEIN-k..........................................
A0A2M8S3A0_9PAST/5-251               .....................nq--VVKNIITRVIQSQDYRIEIVNLLNAEFLQFSID.FFKRIV..DAK..MsaK..TI..D..MEWyKQN.FL.AE.NLPS...-.------N---...DI...IIHSGLNKKTISNMYG-SARKSIVI..EASNE.HFDTL..YNSICHLV..ENEQEK...VDLTLT..IKFQ.GVSVDLSISESLIVINTLAVKRAELRGGLWSTAGKRVEKYLVLTLCHLFQIP..SEYY..DS..S...NFV...-....K...D....REKN......VDREVDFYFIK.E.-NKKY.LCEVKLMGKGNPESADAIFARN..T..NIFIADTLSE---qnk........................................
A0A238HF71_9NEIS/5-252               ....................nqv---TKNIIKRVIQSKDYRIEIVNLLNAEFLQFSID.FFKKVV..AAK..L..N..--..-..---.-SQ.YI.TI.DWYK...T.YFLADTLSKD...EI...IIHSGLNEKTIKNMYG-TTAKSAVI..DASSE.HFETL..YNSIQSLV..ENEQNE...IDLTLT..IKLK.GVSVDLSISESLIVINTLAVKRSQIRGGLWSTAGKSVEKYLMLSLCQLYQVS..EIHY..DS..S...TFV...-....K...D....KSKK......VDREIDFYLID.D.NKQKY.LCEVKLMGAGNPESADAIIARN..S..HVFVADTLSQ---qnk........................................
A0A2H5XEU3_UNCXX/35-199              ......................t-DVLRQVVFDVMCGRNLRD-ATEMLTRKHIALVNA.ALVVLF..MQG..L..K..-Y..R..SDF.VSR.LA.DI.VNDE...L.QQKHSKTERW...VL...QWLLGLTDKAAQNILR---DDLIAL..ETYKEqYMRVC..QEVVAEC-..ERNFGT...LKGALE..ISSGeWAHINWEFL--YYLLNAVGAGTLAIRGSEN----------------------..----..--..-...---...-....-...-....----......-----------.-.-----.----------------------..-..-------------qymanf.....................................
A0A1E5IID0_ENDTX/5-254               .......................KEIIDNAVSKLIKGDDYRDEVVNAINVSFLDFAVD.FFKKII..TAK..I..K..ENnvD..LAW.YKK.HF.IA.A-DN...-.---ISSDDK-...--...AIFSGINKKTITNIHG-SATKKIVL..DIASA.NFEYL..SELISSLE..KDSESG...IVLNIK..ISYK.EVSVELSLIESLLVINALATKKIAIRGGAWSSIGKKIEKPLLLKLCKLCKVP..KE-Y..IN..S...SVF...K....K...N....EALN......FDREVDFKLYD.SiKEKEY.RVEVKLMGRGNPESADVIYARG..T..DIFIADTLSE---qnr........................................
B5YIR7_THEYD/2-251                   .......................KELIGKIVHSVLTGQDYRTYVLATINKRFLDKAQK.LISEIF..EYK..R..K..--..-..---.GNN.WL.EK.LLDD...T.YKKQGKNNKF...KL...LWFGGLNDKTVKNMTGGTSAKRVCL..DLGKK.NIKAL..QLLLEEF-..ENSEDL...YQMIIN..IEKD.KEKISLDYIESLFFMNIISAMKLTIQGGAWSEVGKKTEKGLLFVIFKMINIP..DERY..IL..T...NEE...M....K...K....KGLV......KNREIDAIVLN.D.KNEAL.TVELKLLGIGNPEIGDEAFSRN..V..NLFLTDKLTEMMK...........................................
A0A2N3HXD0_9BACT/5-246               .....................td--AKKNIIKKVISNQDYRDEVLVIIDEIFLDYCIS.FFKQVV..YAK..I..D..--..A..LGE.KSD.WY.KK.VFLN...-.----PDLPKE...QI...AINSGLNMKSITNAFN-SSKKEVVI..QASYD.NYNRL..QKTINDLV..SNGNNF...E-IKLS..IKFK.DVAVDLTVAESLIVINTIAVKRAEIRGGMWSAVGKQVEKPLMTTLCMLFNVP..FEYH..V-..Q...DSN...-....-...P....DSF-......--REVDFYVLS.K.DGKKL.RTEVKLMGKGNPESADAIFARQ..P..AIFLADKLSD---knk........................................
A0A0A2EPE0_9PORP/5-250               .....................dq--IVKNIITRVIKSEDYRIEIVNLINAEFLQFSVD.FFKKIV..TAK..L..N..--..-..---.SED.IT.ID.W---...-.YKRYFMSEGLsseDI...AINSGLNKKTISNMYG-SATRTIVI..EASNE.HFESL..YQSIQTLVeiEKEIDL...V-LTIK..LKG-.-VSVDLNVSESLVVINTLAVKRAALRGGLWSTAGKSVEKYLMLTLCKLYQVP..ESNY..DA..K...HF-...V....K...D....KGKK......VDREIDFYLLE.R.DNKYL.-CEVKLMGKGNPESADAIIARS..T..NIFVADTLSQ---qnk........................................
A0A3A9CDM4_UNCXX/28-160              ......................a-EGIRGIVKEVLLGGNIRD-FTEFITQKRLIESYA.ALLDLY..-MG..R..I..GN..H..VDS.VEE.YA.GC.VLND...Y.MEARGRDPKT...LD...LWLLGLTRKGFDNITR---------..-----.-----..--------..------...------..----.----------------------------------------------------..----..--..-...---...-....-...-....----......-----------.-.-----.----------------------..-..-------------dniqdykysftasvediseglekeygpvsgtievgarklslnw
#=GC seq_cons                        .........................hlKsllp+llpGpDYRh.llshIstcFLphshs.ahpcll..psK..h..c......s..hsh.hpp.hh.pp.hhsp......pt.spp.t.....l...th.uGLNcKTIpNhhs.osp+clll..phupc.ph-tL...pslpplh..-pppsh...h.lslp..lchp.tsuV-LslsESLlVlNslAsK+hslRGGhWSssGKplEK.LhhoLCpLhsls..pppa......p...ph.........p...p....pph........pRElDFhlhp.s.pppth.+sEVKLMG+GNPEsADshhARt..s..plFlADpLSp...ppp........................................
//