#=GF ID   RalF_SCD
#=GF AC   PF18248.6
#=GF DE   RalF C-terminal Sec-7 capping domain
#=GF AU   Smart A;0000-0002-6965-5633
#=GF SE   ECOD:EUF03413
#=GF GA   25.00 25.00;
#=GF TC   25.20 133.10;
#=GF NC   24.70 20.30;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 8 -Z 90746521 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   15520000
#=GF RT   The structure of RalF, an ADP-ribosylation factor guanine
#=GF RT   nucleotide exchange factor from Legionella pneumophila, reveals
#=GF RT   the presence of a cap over the active site.
#=GF RA   Amor JC, Swails J, Zhu X, Roy CR, Nagai H, Ingmundson A, Cheng
#=GF RA   X, Kahn RA;
#=GF RL   J Biol Chem. 2005;280:1392-1400.
#=GF DR   INTERPRO; IPR040917;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is the C-terminal domain of RalF protein present in
#=GF CC   Legionella pneumophilia. RalF is secreted into host cytosol via
#=GF CC   the Dot/Icm type IV transporter where it acts to recruit
#=GF CC   ADP-ribosylation factor (Arf) to pathogen-containing phagosomes
#=GF CC   in the establishment of a replicative organelle. This domain
#=GF CC   forms a cap over the active site in the Sec7 domain and so is
#=GF CC   referred to as the Sec7-capping domain [1].
#=GF SQ   7
#=GS Q9ZDF5_RICPR/200-351      AC Q9ZDF5.1
#=GS A0A0W0YWQ9_9GAMM/198-344  AC A0A0W0YWQ9.1
#=GS A0A0W0TW34_9GAMM/308-458  AC A0A0W0TW34.1
#=GS A0A222NZB0_9GAMM/327-476  AC A0A222NZB0.1
#=GS D3HS78_LEGLN/200-350      AC D3HS78.1
#=GS A0A3S0FR71_9RICK/203-354  AC A0A3S0FR71.1
#=GS Q5ZU58_LEGPH/198-343      AC Q5ZU58.1
Q9ZDF5_RICPR/200-351                 d-SSPGYQINNISSQNDKTFKQLNQFLEEK.R-NIQNIFPKLQ..NNnLTIEFKNPKTFLSKFTGYKGSVIIKDEKS-G.AAEIQVYKPSIFSRWFLGEKSKIIIQPLREEgrqpsEQSLKLAAQITASFETKVTSIKATYDYLKEDLKSQYDN----irnpk
A0A0W0YWQ9_9GAMM/198-344             .KVNPGYEINFGASDNDPAFEKLNSIMGSS.VIDPKNLIPGIS..DS.VKATVAKPKPWLAFLTGYEGTILLADEKTKG.EASIQIYKPGIFSKLFFGEQPKVIVQPAGTN.....KASIDLAAKVAAGFKTPVSSIKATYDYEHKDLESAYQHEKKL.....
A0A0W0TW34_9GAMM/308-458             .KASPGYEFNSPTLDHDSTFNKLDLLLQSP.A-KAQVIFPGIG..EH.VKATADQPKSWLSILTGYKGTITLTNENTQEiLATLQVYSPSVISKWIFGDTHRVIIQPISQNgl.vaQAKIDLAAKIAARFELPVTHVKATYDYLKDDLQAAYNKEKGL.....
A0A222NZB0_9GAMM/327-476             .KIEPGYVIASSALNHDSTLNRLNSLLHSS.IIEARHLFPGVG..NT.IKLTITQPKSWLTIFTGYEGTITLSNEH-ST.LASIQIYAPNFLSRWLFGKQPKVIIQPICKDgk.aaPEAIELAAKIAASFETPVTSIKATYDYMKSDLQSRYAEKKK-t....
D3HS78_LEGLN/200-350                 .KTTPGYLLTSSTLDDDLMFKKLDLLLQSS.ISTTEEIFPEIA..DN.ITVTFDKPKAWLKAFIGYEGTIKFTTESGRE.LANIQIYKPSLVSKWLFGAQPKVIIQPIDQDe..npKEAIELAAKIAVLFESPVNSFKATYDYELSELISAYDQQHK-el...
A0A3S0FR71_9RICK/203-354             .KISPGIQMNTSLLDYDQTFKSLKTFMNEAgNGQLKNVFPNISnaDS.LEAQVDKPRSLLANLMGYNGTLNLTDKETGA.KCSVQIYEPNIFSKILFNDKPKIIIQPLGDEn...qDHSLKLAAQVEASFRTPPETFKSTYGYEADSMEKEYRISK--sa...
Q5ZU58_LEGPH/198-343                 .KTSPGYELTSTTLNKDSTFKKLDSFLHST.DVNINTVFPGIG..DN.VKTTVDQPKSWLSFFTGYKGTITLTDNKTSA.QATIQVYTPNIFSKWLFGEQPRVIIQP-GQT.....KESIDLAAKAAADFSSPVKNFKATYDYEVGDLIKAYDNQKKL.....
#=GC seq_cons                        .KsoPGYplsossLspDpTFc+LsphLpSs.h.phpslFPsIu..-s.lcsThcpPKoWLuhhTGYcGTIpLosEcops.hAoIQlYpPslhSKWlFG-pPKVIIQPlspst....cpuI-LAAKlAAsFcoPVsohKATYDY.tsDLputYsppKt......
//