GenomeNet

Database: Pfam
Entry: Reprolysin_3
LinkDB: Reprolysin_3
Original site: Reprolysin_3 
#=GF ID   Reprolysin_3
#=GF AC   PF13582.9
#=GF DE   Metallo-peptidase family M12B Reprolysin-like
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   manual
#=GF GA   22.40 22.40;
#=GF TC   22.40 22.40;
#=GF NC   22.30 22.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0126
#=GF DR   MEROPS; M12;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This zinc-binding metallo-peptidase has the characteristic
#=GF CC   binding motif HExxGHxxGxxH of Reprolysin-like peptidases of
#=GF CC   family M12B.
#=GF SQ   690
#=GS A0A4R6PP94_9GAMM/198-327    AC A0A4R6PP94.1
#=GS A0A498SDE8_ACAVI/34-175     AC A0A498SDE8.1
#=GS A0A2W1BC45_HELAM/1-117      AC A0A2W1BC45.1
#=GS G8TBP4_NIAKG/214-298        AC G8TBP4.1
#=GS A0A6P8WQS6_DROAB/345-493    AC A0A6P8WQS6.1
#=GS A0A1G9S874_9EURY/79-195     AC A0A1G9S874.1
#=GS A0A7M7QFS8_NASVI/292-439    AC A0A7M7QFS8.1
#=GS A0A5N5TE66_9CRUS/1-115      AC A0A5N5TE66.1
#=GS F4X7T0_ACREC/223-372        AC F4X7T0.1
#=GS A0A131ZUY0_SARSC/256-407    AC A0A131ZUY0.1
#=GS A0A2K6UNA7_SAIBB/237-362    AC A0A2K6UNA7.1
#=GS A0A2T5X859_9MICO/248-344    AC A0A2T5X859.1
#=GS A0A202E0Q0_9BACT/239-329    AC A0A202E0Q0.1
#=GS A0A6P8Z8R7_THRPL/126-274    AC A0A6P8Z8R7.1
#=GS A0A2A3EG91_APICC/229-377    AC A0A2A3EG91.1
#=GS A0A6I8TVZ5_AEDAE/369-516    AC A0A6I8TVZ5.1
#=GS A0A2R9C090_PANPA/231-356    AC A0A2R9C090.1
#=GS H9J4C6_BOMMO/5-128          AC H9J4C6.1
#=GS A0A164YE23_9CRUS/203-320    AC A0A164YE23.1
#=GS A0A672JP32_SALFA/37-158     AC A0A672JP32.1
#=GS A0A0D8CYF9_9GAMM/46-175     AC A0A0D8CYF9.1
#=GS A0A1A9F047_9GAMM/165-255    AC A0A1A9F047.1
#=GS A0A143G368_9GAMM/421-526    AC A0A143G368.1
#=GS B4J6M0_DROGR/156-304        AC B4J6M0.1
#=GS A0A139XFV3_9CYAN/92-175     AC A0A139XFV3.1
#=GS A0A553FW49_9BACT/295-409    AC A0A553FW49.1
#=GS A0A2H2IJA0_CAEJA/2-102      AC A0A2H2IJA0.1
#=GS A0A182GWD7_AEDAL/19-109     AC A0A182GWD7.1
#=GS A0A0A1DP59_NOCSI/203-277    AC A0A0A1DP59.2
#=GS A0A6B3I1P6_9ACTN/31-152     AC A0A6B3I1P6.1
#=GS A0A1V1PVY4_9PROT/336-434    AC A0A1V1PVY4.1
#=GS A0A232F2Q4_9HYME/217-359    AC A0A232F2Q4.1
#=GS A0A0Q8E8F2_9ACTN/160-292    AC A0A0Q8E8F2.1
#=GS A0A151XGZ3_9HYME/236-385    AC A0A151XGZ3.1
#=GS E2AEB9_CAMFO/262-410        AC E2AEB9.1
#=GS A0A653DFQ7_CALMS/145-251    AC A0A653DFQ7.1
#=GS A0A226D084_FOLCA/91-183     AC A0A226D084.1
#=GS A0A368NSF7_9GAMM/693-792    AC A0A368NSF7.1
#=GS A0A166U934_9GAMM/196-335    AC A0A166U934.1
#=GS A0A6I8TJT0_AEDAE/369-517    AC A0A6I8TJT0.1
#=GS A0A1Z4UNT2_9CYAN/82-190     AC A0A1Z4UNT2.1
#=GS A0A1D2NFS3_ORCCI/237-385    AC A0A1D2NFS3.1
#=GS A0KI44_AERHH/224-350        AC A0KI44.1
#=GS A0A0D3LMB1_9BACT/191-295    AC A0A0D3LMB1.1
#=GS A0A1D1UF96_RAMVA/354-506    AC A0A1D1UF96.1
#=GS A0A6I9WT05_9HYME/262-410    AC A0A6I9WT05.1
#=GS B4MYD0_DROWI/335-483        AC B4MYD0.2
#=GS A0A143PP17_9BACT/60-163     AC A0A143PP17.1
#=GS A0A5C6D3I1_9BACT/4-78       AC A0A5C6D3I1.1
#=GS A0A6I8TVV8_AEDAE/369-517    AC A0A6I8TVV8.1
#=GS G2FBV7_9GAMM/26-147         AC G2FBV7.1
#=GS G4TUG9_SERID/87-215         AC G4TUG9.1
#=GS B8CEJ6_THAPS/285-386        AC B8CEJ6.1
#=GS A0A1Y2K2J6_9PROT/284-411    AC A0A1Y2K2J6.1
#=GS A0A0C4YIN1_9BURK/405-522    AC A0A0C4YIN1.1
#=GS A0A0C5XGC8_NOCSI/197-273    AC A0A0C5XGC8.1
#=GS A0A3N0GV73_9ACTN/201-286    AC A0A3N0GV73.1
#=GS A0A0Q9W4L4_DROVI/348-496    AC A0A0Q9W4L4.1
#=GS A0A0P8XLY8_DROAN/334-481    AC A0A0P8XLY8.1
#=GS A0A517SEI1_9PLAN/179-243    AC A0A517SEI1.1
#=GS A0A4S2KVC1_9HYME/327-475    AC A0A4S2KVC1.1
#=GS A0A653DFR5_CALMS/145-236    AC A0A653DFR5.1
#=GS A0A498MGF1_LABRO/41-173     AC A0A498MGF1.1
#=GS A0A3F2V293_9GAMM/50-159     AC A0A3F2V293.1
#=GS F2U7M4_SALR5/213-303        AC F2U7M4.1
#=GS A0A1U7IIF1_9CYAN/84-235     AC A0A1U7IIF1.1
#=GS I1RV30_GIBZE/31-159         AC I1RV30.1
#=GS A0A0D6SZD2_9PSED/47-176     AC A0A0D6SZD2.1
#=GS A0A1R4G1H6_9MICO/138-245    AC A0A1R4G1H6.1
#=GS A0A1J1HM13_9DIPT/1-59       AC A0A1J1HM13.1
#=GS A0A0L7L0R3_9NEOP/125-244    AC A0A0L7L0R3.1
#=GS A0A0G3C076_9BURK/199-310    AC A0A0G3C076.1
#=GS A0A2K5CU40_AOTNA/233-358    AC A0A2K5CU40.1
#=GS A0A2G3K2J5_9BURK/213-347    AC A0A2G3K2J5.1
#=GS A0A4E0QQA4_9GAMM/222-334    AC A0A4E0QQA4.1
#=GS K9PJ53_9CYAN/88-190         AC K9PJ53.1
#=GS A0A344U9C4_9ACTN/138-265    AC A0A344U9C4.1
#=GS A0A1I2GKP3_9MICO/201-312    AC A0A1I2GKP3.1
#=GS A0A1G9CMB4_9MICO/111-232    AC A0A1G9CMB4.1
#=GS A0A195E2A5_9HYME/235-384    AC A0A195E2A5.1
#=GS U5LBD7_9BACI/118-229        AC U5LBD7.1
#=GS A2DVS4_TRIVA/196-324        AC A2DVS4.1
#=GS A0A1M6A3N3_9FLAO/235-359    AC A0A1M6A3N3.1
#=GS A0A6N9YKT9_9ACTN/163-283    AC A0A6N9YKT9.1
#=GS A9AVC2_HERA2/241-365        AC A9AVC2.1
#=GS A0A2G1XK16_STRCJ/131-259    AC A0A2G1XK16.1
#=GS A0A4R6KTI1_9ACTN/196-290    AC A0A4R6KTI1.1
#=GS A0A1H4N1R6_9MICC/116-226    AC A0A1H4N1R6.1
#=GS A0A5C5VYM9_9BACT/96-194     AC A0A5C5VYM9.1
#=GS A0A6J2JSM3_BOMMA/377-525    AC A0A6J2JSM3.1
#=GS T1JTM2_TETUR/312-463        AC T1JTM2.1
#=GS A0A2K6UC52_SAIBB/113-233    AC A0A2K6UC52.1
#=GS B4LM86_DROVI/348-496        AC B4LM86.2
#=GS A0A317F5A0_9PROT/204-291    AC A0A317F5A0.1
#=GS D2Q3Z1_KRIFD/164-294        AC D2Q3Z1.1
#=GS A0A0P9BW09_DROAN/334-481    AC A0A0P9BW09.1
#=GS A0A6A4W2Y6_AMPAM/301-448    AC A0A6A4W2Y6.1
#=GS B8C8W5_THAPS/434-584        AC B8C8W5.1
#=GS D2R4B1_PIRSD/167-249        AC D2R4B1.1
#=GS A0A2Y9SXZ0_PHYMC/187-319    AC A0A2Y9SXZ0.2
#=GS A0A4T0URY5_9ACTN/213-311    AC A0A4T0URY5.1
#=GS A0A6B3LEB6_9BACT/173-290    AC A0A6B3LEB6.1
#=GS A0A1I3F0B1_9PLAN/127-238    AC A0A1I3F0B1.1
#=GS A0A653CQU9_CALMS/272-362    AC A0A653CQU9.1
#=GS A0A4S8MZY2_9ACTN/171-263    AC A0A4S8MZY2.1
#=GS A0A195E1M9_9HYME/263-411    AC A0A195E1M9.1
#=GS A0A2P8WFK1_9CYAN/112-169    AC A0A2P8WFK1.1
#=GS A0A4P7IE71_9ACTN/238-319    AC A0A4P7IE71.1
#=GS A0A5C6D7R1_9BACT/178-250    AC A0A5C6D7R1.1
#=GS A0A5C1QIR4_9SPIO/146-259    AC A0A5C1QIR4.1
#=GS A0A517T0E8_9BACT/192-276    AC A0A517T0E8.1
#=GS Q9KN69_VIBCH/44-193         AC Q9KN69.1
#=GS A4XZZ3_PSEMY/46-175         AC A4XZZ3.1
#=GS A0A1Y1RNM9_9MICC/139-227    AC A0A1Y1RNM9.1
#=GS A0A5J4IW57_9FLAO/98-217     AC A0A5J4IW57.1
#=GS A0A151IAL5_9HYME/237-385    AC A0A151IAL5.1
#=GS A0A4Q5XHV9_9DELT/594-697    AC A0A4Q5XHV9.1
#=GS A0A3L8SNC0_CHLGU/2-54       AC A0A3L8SNC0.1
#=GS C0BIR1_FLABM/48-169         AC C0BIR1.1
#=GS A0A226EGW8_FOLCA/210-361    AC A0A226EGW8.1
#=GS A0A233HP53_9VIBR/44-194     AC A0A233HP53.1
#=GS A0A6L7EWP7_9ACTN/146-262    AC A0A6L7EWP7.1
#=GS A0A6P8YFB9_DROAB/345-493    AC A0A6P8YFB9.1
#=GS B8BUR0_THAPS/296-424        AC B8BUR0.1
#=GS K0S7W5_THAOC/1-39           AC K0S7W5.1
#=GS A0A433T1U9_ELYCH/16-167     AC A0A433T1U9.1
#=GS A0A087TA44_STEMI/34-185     AC A0A087TA44.1
#=GS K0RZE1_THAOC/304-449        AC K0RZE1.1
#=GS A0A6G0ZLY7_APHCR/312-460    AC A0A6G0ZLY7.1
#=GS A0A1J1LWJ5_9CYAN/125-234    AC A0A1J1LWJ5.1
#=GS A0A100Y3P8_9ACTN/156-278    AC A0A100Y3P8.1
#=GS A3UB25_CROAH/237-358        AC A3UB25.1
#=GS A0A6I8VDK8_DROPS/339-487    AC A0A6I8VDK8.1
#=GS E0VTL9_PEDHC/340-488        AC E0VTL9.1
#=GS A0A6P4E7A6_DRORH/338-485    AC A0A6P4E7A6.1
#=GS A0A0Q7ZEW9_9ACTN/162-276    AC A0A0Q7ZEW9.1
#=GS A0A4P7JPZ3_9GAMM/242-367    AC A0A4P7JPZ3.1
#=GS A0A1D8G898_9ACTN/238-360    AC A0A1D8G898.1
#=GS A0A2K5SIS5_CEBIM/238-363    AC A0A2K5SIS5.1
#=GS A0A519MAP2_9BURK/84-209     AC A0A519MAP2.1
#=GS A9UWU2_MONBE/410-553        AC A9UWU2.1
#=GS F2UNU0_SALR5/210-317        AC F2UNU0.1
#=GS B3PH79_CELJU/39-149         AC B3PH79.1
#=GS A0A518ELF6_9BACT/201-334    AC A0A518ELF6.1
#=GS A0A2K6KL03_RHIBE/235-360    AC A0A2K6KL03.1
#=GS A0A6J3L3D8_9HYME/261-409    AC A0A6J3L3D8.1
#=GS A0A4T0UL57_9ACTN/188-282    AC A0A4T0UL57.1
#=GS A0A7E5VIR6_TRINI/382-530    AC A0A7E5VIR6.1
#=GS A0A671NTK6_9TELE/300-422    AC A0A671NTK6.1
#=GS A0A166XRQ3_9GAMM/40-167     AC A0A166XRQ3.1
#=GS A0A226DRN7_FOLCA/192-327    AC A0A226DRN7.1
#=GS A0A653CQE1_CALMS/272-371    AC A0A653CQE1.1
#=GS A0A158N9V5_ATTCE/245-394    AC A0A158N9V5.1
#=GS C7M751_CAPOD/199-332        AC C7M751.1
#=GS A0A545UTB3_9HYPO/66-189     AC A0A545UTB3.1
#=GS A0A1Z4BZN7_9GAMM/193-292    AC A0A1Z4BZN7.1
#=GS A0A4R6XTA3_9GAMM/183-322    AC A0A4R6XTA3.1
#=GS A0A2I3M8I0_PAPAN/235-360    AC A0A2I3M8I0.1
#=GS A0A2T6E4L6_9GAMM/362-433    AC A0A2T6E4L6.1
#=GS A0A194QQB5_PAPMA/313-461    AC A0A194QQB5.1
#=GS A0A1P8WQR4_9PLAN/95-220     AC A0A1P8WQR4.1
#=GS A0A3N0CGZ6_9ACTN/181-300    AC A0A3N0CGZ6.1
#=GS A0A3G2G673_9FLAO/144-327    AC A0A3G2G673.1
#=GS A0A2Z5QXX5_9MICC/65-140     AC A0A2Z5QXX5.1
#=GS A0A2A4KA92_HELVI/350-497    AC A0A2A4KA92.1
#=GS A0A672SFL7_SINGR/72-217     AC A0A672SFL7.1
#=GS T1H5P9_MEGSC/137-213        AC T1H5P9.1
#=GS A0A5B1LM80_9ACTN/221-306    AC A0A5B1LM80.1
#=GS F2UHM2_SALR5/302-397        AC F2UHM2.1
#=GS A0A4R4ZVU2_9ACTN/180-288    AC A0A4R4ZVU2.1
#=GS A0A6C7ECA7_ILUCY/179-276    AC A0A6C7ECA7.1
#=GS A0A1L6L9U9_9DELT/224-348    AC A0A1L6L9U9.1
#=GS B4I8T0_DROSE/337-485        AC B4I8T0.1
#=GS A0A7M7H714_NASVI/289-437    AC A0A7M7H714.1
#=GS B7P5A5_IXOSC/1-54           AC B7P5A5.1
#=GS A0A0R3PXV7_ANGCS/1-69       AC A0A0R3PXV7.1
#=GS L8GUY9_ACACA/184-306        AC L8GUY9.1
#=GS W8EUQ8_9BACT/211-304        AC W8EUQ8.1
#=GS A0A2N5Y5R4_9GAMM/204-290    AC A0A2N5Y5R4.1
#=GS A0A0F0HJH1_9ACTN/139-266    AC A0A0F0HJH1.1
#=GS A9AZ68_HERA2/240-364        AC A9AZ68.1
#=GS A0A2G1XP38_STRCJ/128-256    AC A0A2G1XP38.1
#=GS A0A5E4M921_9HEMI/266-414    AC A0A5E4M921.1
#=GS T1IZN0_STRMM/273-409        AC T1IZN0.1
#=GS A0A316F001_9BURK/234-352    AC A0A316F001.1
#=GS A0A232FHS3_9HYME/248-428    AC A0A232FHS3.1
#=GS A0A7M7G4X2_NASVI/275-423    AC A0A7M7G4X2.1
#=GS A0A401Y8I5_9ACTN/163-255    AC A0A401Y8I5.1
#=GS A0A0L8HWG1_OCTBM/111-251    AC A0A0L8HWG1.1
#=GS A0A3R7SY12_PENVA/454-588    AC A0A3R7SY12.1
#=GS A0A252DER1_9NOSO/514-604    AC A0A252DER1.1
#=GS A0A4Q6B4J2_9PROT/312-391    AC A0A4Q6B4J2.1
#=GS A0A2I0TCK4_LIMLA/7-87       AC A0A2I0TCK4.1
#=GS A0A4Q5NNS8_9BACT/196-316    AC A0A4Q5NNS8.1
#=GS A0A6J2JTB1_BOMMA/377-524    AC A0A6J2JTB1.1
#=GS A0A6J2Y2B8_SITOR/296-444    AC A0A6J2Y2B8.1
#=GS A0A151JX04_9HYME/66-214     AC A0A151JX04.1
#=GS B7Q897_IXOSC/192-334        AC B7Q897.1
#=GS A0A154P2V4_DUFNO/329-428    AC A0A154P2V4.1
#=GS A0A5E4C0S8_MARMO/56-161     AC A0A5E4C0S8.1
#=GS A0A6J3C3C2_GALME/387-535    AC A0A6J3C3C2.1
#=GS A0A1R4H4X4_9GAMM/199-273    AC A0A1R4H4X4.1
#=GS A0A0S9R861_9ACTN/166-269    AC A0A0S9R861.1
#=GS Q3JD54_NITOC/242-366        AC Q3JD54.1
#=GS A0A1M6J0H5_9FLAO/262-393    AC A0A1M6J0H5.1
#=GS A0A3R7LWC4_PENVA/1-97       AC A0A3R7LWC4.1
#=GS A0A4P9VS47_9GAMM/51-179     AC A0A4P9VS47.1
#=GS J9JNX6_ACYPI/270-418        AC J9JNX6.2
#=GS A0A2W2CDZ9_9RHIZ/185-291    AC A0A2W2CDZ9.1
#=GS A0A6J1QA22_9HYME/237-385    AC A0A6J1QA22.1
#=GS A0A249SZE4_9BACT/204-298    AC A0A249SZE4.1
#=GS A0A1U9N6R3_9GAMM/51-161     AC A0A1U9N6R3.1
#=GS A0A4W2BW95_BOBOX/104-230    AC A0A4W2BW95.1
#=GS A0A2Z6UT13_GLASK/198-318    AC A0A2Z6UT13.1
#=GS A0A7M7QFG0_NASVI/292-439    AC A0A7M7QFG0.1
#=GS A0A2R2MS19_LINUN/277-421    AC A0A2R2MS19.1
#=GS A0A4Q5VBB3_9GAMM/58-168     AC A0A4Q5VBB3.1
#=GS A0A5N6MQC5_9MICC/183-303    AC A0A5N6MQC5.1
#=GS B0C9C3_ACAM1/239-338        AC B0C9C3.1
#=GS A0A5N4B159_PHOPY/314-461    AC A0A5N4B159.1
#=GS A0A1Y3B8A4_EURMA/284-435    AC A0A1Y3B8A4.1
#=GS A0A232FEV2_9HYME/263-423    AC A0A232FEV2.1
#=GS A0A2T6E271_9BACT/287-383    AC A0A2T6E271.1
#=GS E4WSD3_OIKDI/14-113         AC E4WSD3.1
#=GS T1FHV8_HELRO/112-243        AC T1FHV8.1
#=GS A0A0Q7Q759_9ACTN/212-295    AC A0A0Q7Q759.1
#=GS A0A6J0BBZ2_NEOLC/264-411    AC A0A6J0BBZ2.1
#=GS A0A542ZB31_RARFA/152-285    AC A0A542ZB31.1
#=GS A0A6B2U8N1_9ACTN/187-288    AC A0A6B2U8N1.1
#=GS A0A4Q2UBU0_9BACT/95-213     AC A0A4Q2UBU0.1
#=GS A0A6A4VJM8_AMPAM/297-445    AC A0A6A4VJM8.1
#=GS B7Q2B9_IXOSC/242-330        AC B7Q2B9.1
#=GS A0A4C1YAF4_EUMVA/11-127     AC A0A4C1YAF4.1
#=GS A0A023C0Z2_9FLAO/208-291    AC A0A023C0Z2.1
#=GS A0A7D5QBV2_9EURY/50-174     AC A0A7D5QBV2.1
#=GS A0A261GNE7_9GAMM/45-173     AC A0A261GNE7.1
#=GS A0A232F158_9HYME/323-470    AC A0A232F158.1
#=GS A0A232FA94_9HYME/650-784    AC A0A232FA94.1
#=GS A0A4P9VJC8_9GAMM/46-168     AC A0A4P9VJC8.1
#=GS A0A6J2Y219_SITOR/296-443    AC A0A6J2Y219.1
#=GS E2BPS3_HARSA/218-360        AC E2BPS3.1
#=GS A0A1R4GYK1_9GAMM/137-265    AC A0A1R4GYK1.1
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B4GBL4_DROPE/339-487                   ...............................................................................................................................k-RYFISFWNGVD.L..RYR...-LLKg............prIR...ISIA.......................GI..I.I.S.RGR...............D...aT....P...Y...L..E..R..NRv..............gRDAI.D..S.A.......AALTDMgk.........................ylfRER.R....L....P.V....Y....D..I.....A...V....A..I.T.K.LDMcrrts....................................aygecnRGTAG...F...A.Y.V...........................GGA.C..V..V.N.KRlek.......................................vnsV.AI..I..E..DT.....G..-..-..GF....SG.I...................................IVAAHEV...G...........HLLGAVHD.................................................
#=GR B4GBL4_DROPE/339-487        pAS   ...........................................................................................................