GenomeNet

Database: Pfam
Entry: SEFIR
LinkDB: SEFIR
Original site: SEFIR 
#=GF ID   SEFIR
#=GF AC   PF08357.14
#=GF DE   SEFIR domain
#=GF AU   Fenech M;0000-0001-7933-4617
#=GF SE   Pfam-B_33671 (release 17.0)
#=GF GA   23.00 23.00;
#=GF TC   23.00 23.10;
#=GF NC   22.90 22.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Interleukin-17_receptor
#=GF CL   CL0173
#=GF RN   [1]
#=GF RM   12765832
#=GF RT   The STIR-domain superfamily in signal transduction, development
#=GF RT   and immunity. 
#=GF RA   Novatchkova M, Leibbrandt A, Werzowa J, Neubuser A, Eisenhaber
#=GF RA   F; 
#=GF RL   Trends Biochem Sci 2003;28:226-229.
#=GF RN   [2]
#=GF RM   22037611
#=GF RT   Evolution of prokaryotic homologues of the eukaryotic SEFIR
#=GF RT   protein domain.
#=GF RA   Wu B, Gong J, Liu L, Li T, Wei T, Bai Z;
#=GF RL   Gene. 2011; [Epub ahead of print]
#=GF DR   INTERPRO; IPR013568;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family comprises IL17 receptors (IL17Rs, e.g. Swiss:Q60943)
#=GF CC   and SEF proteins (e.g. Swiss:Q8QHJ9). The latter are feedback
#=GF CC   inhibitors of FGF signalling and are also thought to be
#=GF CC   receptors. Due to its similarity to the TIR domain
#=GF CC   (Pfam:PF01582), the SEFIR region is thought to be involved in
#=GF CC   homotypic interactions with other SEFIR/TIR-domain-containing
#=GF CC   proteins. Thus, SEFs and IL17Rs may be involved in
#=GF CC   TOLL/IL1R-like signalling pathways [1].
#=GF SQ   2883
#=GS A0A672JNP5_SALFA/3-93       AC A0A672JNP5.1
#=GS A0A2K6G146_PROCO/498-651    AC A0A2K6G146.1
#=GS A0A2Y9D6L6_TRIMA/513-666    AC A0A2Y9D6L6.1
#=GS A0A1U7TU35_CARSF/387-528    AC A0A1U7TU35.1
#=GS A0A3Q3NDB5_9TELE/340-497    AC A0A3Q3NDB5.1
#=GS A0A285ZWA2_9SPHI/237-353    AC A0A285ZWA2.1
#=GS A0A3Q2D3P7_CYPVA/333-540    AC A0A3Q2D3P7.1
#=GS H3A1T7_LATCH/314-408        AC H3A1T7.1
#=GS A0A6P5J5L3_PHACI/356-511    AC A0A6P5J5L3.1
#=GS A0A2H2IJI5_CAEJA/238-389    AC A0A2H2IJI5.1
#=GS A0A0V1NNJ0_9BILA/486-647    AC A0A0V1NNJ0.1
#=GS A0A0V1N8K1_9BILA/462-628    AC A0A0V1N8K1.1
#=GS A0A402ERZ9_9SAUR/497-651    AC A0A402ERZ9.1
#=GS G1T6M7_RABIT/414-569        AC G1T6M7.2
#=GS A0A662YTV8_ACIRT/385-478    AC A0A662YTV8.1
#=GS A0A6P3QJX7_PTEVA/380-539    AC A0A6P3QJX7.1
#=GS A0A4W5MVL4_9TELE/287-410    AC A0A4W5MVL4.1
#=GS A0A016UGY5_9BILA/371-497    AC A0A016UGY5.1
#=GS G1L6L9_AILME/332-479        AC G1L6L9.2
#=GS G3NIB5_GASAC/314-485        AC G3NIB5.1
#=GS A0A2Y9D6J7_TRIMA/212-366    AC A0A2Y9D6J7.1
#=GS A0A5C6MQ41_9TELE/445-616    AC A0A5C6MQ41.1
#=GS A0A6P7G0L6_DIAVI/316-448    AC A0A6P7G0L6.1
#=GS A0A327NJ73_9BACT/7-146      AC A0A327NJ73.1
#=GS A0A6A5ER34_PERFL/445-609    AC A0A6A5ER34.1
#=GS A0A542DQB4_9PSEU/19-150     AC A0A542DQB4.1
#=GS A0A7I4NLS6_BRUMA/364-517    AC A0A7I4NLS6.1
#=GS A0A3M6UDK9_POCDA/25-168     AC A0A3M6UDK9.1
#=GS A0A3Q7V7I3_URSAR/500-653    AC A0A3Q7V7I3.1
#=GS A0A060XVL7_ONCMY/28-173     AC A0A060XVL7.1
#=GS A0A3Q7UHF6_VULVU/508-646    AC A0A3Q7UHF6.1
#=GS A0A662YWQ0_ACIRT/339-481    AC A0A662YWQ0.1
#=GS A0A1S3P1G8_SALSA/356-515    AC A0A1S3P1G8.1
#=GS A0A663ES47_AQUCH/521-689    AC A0A663ES47.1
#=GS A0A7E4W8A5_PANRE/439-583    AC A0A7E4W8A5.1
#=GS A0A6J1UNI0_9SAUR/332-479    AC A0A6J1UNI0.1
#=GS A0A6I9LD21_PERMB/329-476    AC A0A6I9LD21.1
#=GS T0NLM9_CAMFR/409-529        AC T0NLM9.1
#=GS F7HL00_MACMU/316-463        AC F7HL00.3
#=GS A0A672YBY8_9TELE/412-578    AC A0A672YBY8.1
#=GS A0A1U8CX19_ALLSI/310-458    AC A0A1U8CX19.1
#=GS K7DNF3_PANTR/498-651        AC K7DNF3.1
#=GS A0A672Q2U4_SINGR/470-657    AC A0A672Q2U4.1
#=GS A0A1S3MCS6_SALSA/511-628    AC A0A1S3MCS6.1
#=GS A0A5E4B0U6_MARMO/329-476    AC A0A5E4B0U6.1
#=GS A0A093IJ02_EURHL/251-393    AC A0A093IJ02.1
#=GS A0A183DRI4_9BILA/420-573    AC A0A183DRI4.1
#=GS A0A2U9BB20_SCOMX/394-551    AC A0A2U9BB20.1
#=GS A0A3S2PMI9_ORYJA/443-621    AC A0A3S2PMI9.1
#=GS A0A4U8V3T0_STECR/388-531    AC A0A4U8V3T0.1
#=GS A0A6J3CT79_AYTFU/335-492    AC A0A6J3CT79.1
#=GS G1N3D6_MELGA/315-469        AC G1N3D6.1
#=GS I17RA_MOUSE/380-539         AC Q60943.1
#=GS A0A673NNQ4_9TELE/342-506    AC A0A673NNQ4.1
#=GS A0A6J0CLB5_PERMB/471-621    AC A0A6J0CLB5.1
#=GS A0A5C6NX91_9TELE/245-377    AC A0A5C6NX91.1
#=GS A0A668TW19_OREAU/274-419    AC A0A668TW19.1
#=GS A0A452G5U7_CAPHI/356-511    AC A0A452G5U7.1
#=GS A0A4D9ENT5_9SAUR/358-512    AC A0A4D9ENT5.1
#=GS A0A2J7PVV3_9NEOP/338-475    AC A0A2J7PVV3.1
#=GS A3KN55_BOVIN/329-475        AC A3KN55.1
#=GS A0A673KND2_9TELE/276-420    AC A0A673KND2.1
#=GS A0A3B3I5V3_ORYLA/345-502    AC A0A3B3I5V3.1
#=GS L8IUT7_9CETA/408-550        AC L8IUT7.1
#=GS A0A656HE22_THINJ/2-141      AC A0A656HE22.1
#=GS A0A6G0J433_LARCR/431-596    AC A0A6G0J433.1
#=GS A0A455B9G8_PHYMC/615-752    AC A0A455B9G8.1
#=GS A0A2J8U1D3_PONAB/408-550    AC A0A2J8U1D3.1
#=GS A0A6J1Y1N6_ACIJB/408-546    AC A0A6J1Y1N6.1
#=GS A0A384AYX2_BALAS/462-615    AC A0A384AYX2.2
#=GS F7FLY9_CALJA/513-676        AC F7FLY9.3
#=GS A0A669E9Q7_ORENI/512-736    AC A0A669E9Q7.1
#=GS A0A5N5MV48_PANHP/273-418    AC A0A5N5MV48.1
#=GS A0A7N4PV35_SARHA/398-540    AC A0A7N4PV35.1
#=GS A0A498SDG6_ACAVI/364-516    AC A0A498SDG6.1
#=GS A0A4W2BRK5_BOBOX/505-586    AC A0A4W2BRK5.1
#=GS G3RZP6_GORGO/378-536        AC G3RZP6.2
#=GS A0A3P8T9Y3_AMPPE/445-609    AC A0A3P8T9Y3.1
#=GS A0A3Q3AS75_KRYMA/269-414    AC A0A3Q3AS75.1
#=GS A0A3Q3H2J1_9LABR/302-419    AC A0A3Q3H2J1.1
#=GS A0A091FUS5_9AVES/314-471    AC A0A091FUS5.1
#=GS A0A6P8TR73_GYMAC/459-632    AC A0A6P8TR73.1
#=GS A0A673HDM7_9TELE/2-58       AC A0A673HDM7.1
#=GS A0A6P6KYZ4_CARAU/209-354    AC A0A6P6KYZ4.1
#=GS L5K831_PTEAL/383-521        AC L5K831.1
#=GS A0A1S3P696_SALSA/338-526    AC A0A1S3P696.1
#=GS A0A6P8I3I8_ACTTE/415-560    AC A0A6P8I3I8.1
#=GS A0A2I3RN84_PANTR/488-565    AC A0A2I3RN84.1
#=GS A0A2R2MTR0_LINUN/319-468    AC A0A2R2MTR0.1
#=GS A0A485NXA5_LYNPA/394-492    AC A0A485NXA5.1
#=GS A0A1S3MCS6_SALSA/642-737    AC A0A1S3MCS6.1
#=GS A0A158PQM3_BRUPA/702-857    AC A0A158PQM3.1
#=GS A0A7N4NNT2_SARHA/344-503    AC A0A7N4NNT2.1
#=GS A0A665X7R4_ECHNA/387-548    AC A0A665X7R4.1
#=GS A0A3P8T8S5_AMPPE/1-83       AC A0A3P8T8S5.1
#=GS A0A0N8JV67_SCLFO/2-122      AC A0A0N8JV67.1
#=GS A0A5N4DWY2_CAMDR/436-608    AC A0A5N4DWY2.1
#=GS A0A6P6DM50_OCTDE/484-637    AC A0A6P6DM50.1
#=GS A0A672ZBL9_9TELE/455-584    AC A0A672ZBL9.1
#=GS A0A195CI74_9HYME/328-464    AC A0A195CI74.1
#=GS V4AFQ5_LOTGI/513-664        AC V4AFQ5.1
#=GS G3U7B7_LOXAF/388-529        AC G3U7B7.1
#=GS W5MX33_LEPOC/97-242         AC W5MX33.1
#=GS A0A553R733_9TELE/461-605    AC A0A553R733.1
#=GS A0A3P9N4I3_POERE/375-528    AC A0A3P9N4I3.1
#=GS E1B8L3_BOVIN/489-569        AC E1B8L3.1
#=GS A0A6P3IEN2_BISBI/322-477    AC A0A6P3IEN2.1
#=GS A0A673H0K1_9TELE/354-518    AC A0A673H0K1.1
#=GS A0A672SZ10_SINGR/357-521    AC A0A672SZ10.1
#=GS A0A3Q3AM90_CHICK/494-651    AC A0A3Q3AM90.1
#=GS A0A4Z2J4Y1_9TELE/283-369    AC A0A4Z2J4Y1.1
#=GS A0A3Q7RJR9_CALUR/468-621    AC A0A3Q7RJR9.1
#=GS A0A195B7X2_9HYME/329-465    AC A0A195B7X2.1
#=GS A0A2P4T2K9_BAMTH/351-508    AC A0A2P4T2K9.1
#=GS A0A484GTZ2_SOUCH/376-531    AC A0A484GTZ2.1
#=GS A0A2I3LZV1_PAPAN/484-637    AC A0A2I3LZV1.1
#=GS A0A484D2I9_PERFV/367-524    AC A0A484D2I9.1
#=GS A0A4W2C2P0_BOBOX/355-515    AC A0A4W2C2P0.1
#=GS A0A2K6DF34_MACNE/316-463    AC A0A2K6DF34.1
#=GS A0A6P8GSE9_CLUHA/353-506    AC A0A6P8GSE9.1
#=GS A0A673WXK7_SALTR/496-670    AC A0A673WXK7.1
#=GS H2U1Y1_TAKRU/384-541        AC H2U1Y1.3
#=GS A0A671VCB6_SPAAU/299-456    AC A0A671VCB6.1
#=GS A0A3P8B123_9BILA/381-536    AC A0A3P8B123.1
#=GS A0A6I9YPW0_9SAUR/517-675    AC A0A6I9YPW0.1
#=GS G1SNN5_RABIT/596-644        AC G1SNN5.3
#=GS H0WEZ1_DANRE/1-113          AC H0WEZ1.1
#=GS A0A2I3NE93_PAPAN/500-653    AC A0A2I3NE93.1
#=GS A0A091FIH9_9AVES/315-469    AC A0A091FIH9.1
#=GS A0A673V3V4_SURSU/319-478    AC A0A673V3V4.1
#=GS A0A452S0L0_URSAM/200-355    AC A0A452S0L0.1
#=GS A0A2T7PZP3_POMCA/403-554    AC A0A2T7PZP3.1
#=GS A0A4V1L5S7_9BACT/4-143      AC A0A4V1L5S7.1
#=GS S4RL08_PETMA/315-473        AC S4RL08.1
#=GS A0A6J0WFK3_ODOVR/329-475    AC A0A6J0WFK3.1
#=GS A0A143XNJ1_9FIRM/18-155     AC A0A143XNJ1.1
#=GS A0A7E6E5X8_9CHIR/493-576    AC A0A7E6E5X8.1
#=GS A0A6F8ZQ10_9TELE/234-372    AC A0A6F8ZQ10.1
#=GS A0A6J3S2Y0_TURTR/669-822    AC A0A6J3S2Y0.1
#=GS A0A6P9B274_PANGU/1-128      AC A0A6P9B274.1
#=GS A0A6P9AMU0_PANGU/223-382    AC A0A6P9AMU0.1
#=GS I17RD_DANRE/355-520         AC Q8QHJ9.2
#=GS F1Q490_CANLF/382-541        AC F1Q490.3
#=GS A0A3P9ABK8_ESOLU/1-93       AC A0A3P9ABK8.2
#=GS A0A671L773_9TELE/190-347    AC A0A671L773.1
#=GS A0A3Q2ECJ6_CYPVA/438-602    AC A0A3Q2ECJ6.1
#=GS A0A096MFJ7_POEFO/256-413    AC A0A096MFJ7.1
#=GS L8IH72_9CETA/329-475        AC L8IH72.1
#=GS A0A665SV93_ECHNA/276-421    AC A0A665SV93.1
#=GS A0A2Y9KRT1_ENHLU/1-91       AC A0A2Y9KRT1.1
#=GS A0A6P6QAH7_CARAU/354-519    AC A0A6P6QAH7.1
#=GS A0A3Q3LF99_9LABR/350-548    AC A0A3Q3LF99.1
#=GS A0A6J8E9Q1_MYTCO/96-248     AC A0A6J8E9Q1.1
#=GS A0A3B3I4P4_ORYLA/441-619    AC A0A3B3I4P4.1
#=GS W5NK39_LEPOC/370-508        AC W5NK39.1
#=GS A0A2K5MEV0_CERAT/488-625    AC A0A2K5MEV0.1
#=GS A0A1A6HMA3_NEOLE/482-632    AC A0A1A6HMA3.1
#=GS A0A452CPJ1_BALAS/503-577    AC A0A452CPJ1.1
#=GS A0A1S3QI11_SALSA/1-111      AC A0A1S3QI11.1
#=GS A0A553PVY0_9TELE/392-546    AC A0A553PVY0.1
#=GS A0A1J4Q982_9ACTN/269-404    AC A0A1J4Q982.1
#=GS A0A1Z4KZD7_NOSLI/9-156      AC A0A1Z4KZD7.1
#=GS A0A484DGI0_PERFV/352-521    AC A0A484DGI0.1
#=GS A0A2Y9HG95_NEOSC/533-671    AC A0A2Y9HG95.1
#=GS A0A2U3WDI6_ODORO/356-511    AC A0A2U3WDI6.1
#=GS A0A3P9Q8F0_POERE/202-340    AC A0A3P9Q8F0.1
#=GS C3Z2Q8_BRAFL/272-423        AC C3Z2Q8.1
#=GS A0A2Y9HML3_NEOSC/540-678    AC A0A2Y9HML3.1
#=GS A0A0L8HV13_OCTBM/454-605    AC A0A0L8HV13.1
#=GS A0A6I9PKR5_9TELE/156-309    AC A0A6I9PKR5.1
#=GS A0A6J3AR98_VICPA/401-505    AC A0A6J3AR98.1
#=GS A0A673V116_SURSU/379-538    AC A0A673V116.1
#=GS A0A5E4AUH7_MARMO/378-537    AC A0A5E4AUH7.1
#=GS ILCR2_CAEEL/415-566         AC Q10128.1
#=GS A0A498MRC3_LABRO/299-466    AC A0A498MRC3.1
#=GS A0A2U9BY28_SCOMX/388-549    AC A0A2U9BY28.1
#=GS A0A3Q0H6Z1_ALLSI/229-383    AC A0A3Q0H6Z1.1
#=GS A0A6P6I0D1_PUMCO/396-538    AC A0A6P6I0D1.1
#=GS H3DJF1_TETNG/288-453        AC H3DJF1.1
#=GS E1BP15_BOVIN/354-509        AC E1BP15.3
#=GS A0A673FSA5_9TELE/464-621    AC A0A673FSA5.1
#=GS A0A6P9DC41_PANGU/396-551    AC A0A6P9DC41.1
#=GS F6X8Y9_CIOIN/318-464        AC F6X8Y9.2
#=GS A0A5A9NDB4_9TELE/371-534    AC A0A5A9NDB4.1
#=GS A0A210PS66_MIZYE/420-567    AC A0A210PS66.1
#=GS A0A3Q7UHG0_VULVU/500-657    AC A0A3Q7UHG0.1
#=GS A0A3Q3WN56_MOLML/338-495    AC A0A3Q3WN56.1
#=GS A0A674MBN7_TAKRU/16-103     AC A0A674MBN7.1
#=GS A0A3Q4B0A1_MOLML/346-503    AC A0A3Q4B0A1.1
#=GS A0A401SIB5_CHIPU/493-646    AC A0A401SIB5.1
#=GS A0A091SDY7_NESNO/328-482    AC A0A091SDY7.1
#=GS A0A3P8WVR4_CYNSE/352-521    AC A0A3P8WVR4.1
#=GS A0A3P9NYD5_POERE/218-388    AC A0A3P9NYD5.1
#=GS A0A3Q4M5E7_NEOBR/414-585    AC A0A3Q4M5E7.1
#=GS A0A3Q1I0Q9_9TELE/318-483    AC A0A3Q1I0Q9.1
#=GS A0A091TD57_PHALP/315-469    AC A0A091TD57.1
#=GS A0A6J0WZN8_ODOVR/589-642    AC A0A6J0WZN8.1
#=GS A0A6J3S343_TURTR/666-819    AC A0A6J3S343.1
#=GS F6SDH0_ORNAN/399-541        AC F6SDH0.3
#=GS A0A5F8H980_MONDO/33-192     AC A0A5F8H980.1
#=GS A0A3Q3GXR9_9LABR/338-509    AC A0A3Q3GXR9.1
#=GS S9Y0H6_CAMFR/332-482        AC S9Y0H6.1
#=GS G3R8Y6_GORGO/610-659        AC G3R8Y6.2
#=GS A0A674KAH5_TERCA/389-531    AC A0A674KAH5.1
#=GS A0A2I3MVQ4_PAPAN/315-473    AC A0A2I3MVQ4.1
#=GS A0A2Y9HG86_NEOSC/544-697    AC A0A2Y9HG86.1
#=GS A0A3Q7X3E0_URSAR/543-592    AC A0A3Q7X3E0.1
#=GS A0A667Y322_9TELE/354-522    AC A0A667Y322.1
#=GS A0A6P8TRB1_GYMAC/402-575    AC A0A6P8TRB1.1
#=GS F7CY29_HORSE/606-660        AC F7CY29.3
#=GS A0A6J0UN96_9SAUR/313-461    AC A0A6J0UN96.1
#=GS A0A3Q1GDV8_9TELE/90-239     AC A0A3Q1GDV8.1
#=GS A0A6J3H9K8_SAPAP/494-647    AC A0A6J3H9K8.1
#=GS A0A6Q2XGF9_ESOLU/311-473    AC A0A6Q2XGF9.1
#=GS A0A5F5Y710_FELCA/319-474    AC A0A5F5Y710.1
#=GS A0A2R9C657_PANPA/483-636    AC A0A2R9C657.1
#=GS H2MSL9_ORYLA/353-520        AC H2MSL9.2
#=GS I3K9J9_ORENI/350-507        AC I3K9J9.2
#=GS A0A3Q0JAM1_DIACI/249-388    AC A0A3Q0JAM1.1
#=GS A0A6J1MMT7_BICAN/348-487    AC A0A6J1MMT7.1
#=GS A0A3Q7RLJ9_CALUR/356-511    AC A0A3Q7RLJ9.1
#=GS A0A6P7IMB7_9TELE/479-665    AC A0A6P7IMB7.1
#=GS A0A6I9JH82_CHRAS/356-510    AC A0A6I9JH82.1
#=GS A0A3N0XP07_ANAGA/363-552    AC A0A3N0XP07.1
#=GS A0A1S3S818_SALSA/300-438    AC A0A1S3S818.1
#=GS A0A2Y9HI28_NEOSC/1-135      AC A0A2Y9HI28.1
#=GS A0A087XE61_POEFO/52-205     AC A0A087XE61.2
#=GS A0A4W3IIM2_CALMI/232-389    AC A0A4W3IIM2.1
#=GS A0A3Q1NNN8_BOVIN/383-543    AC A0A3Q1NNN8.1
#=GS A0A4W4EEG9_ELEEL/5-100      AC A0A4W4EEG9.1
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#=GS L8YCR1_TUPCH/345-500        AC L8YCR1.1
#=GS L8Y266_TUPCH/267-414        AC L8Y266.1
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#=GS A0A384D8E2_URSMA/340-499    AC A0A384D8E2.1
#=GS A0A6P6HP79_PUMCO/520-673    AC A0A6P6HP79.1
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#=GS A0A341D199_NEOAA/488-544    AC A0A341D199.1
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#=GS G3GX31_CRIGR/157-307        AC G3GX31.1
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#=GS I17RB_MOUSE/329-476         DR PDB; 3VBC A; 329-476;
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M3YZG2_MUSPF/329-476                   ................................i-KVLVVYPC...EI.CF...H.-..H...TV.C.HFTEFLQ.NH.C...RSEV..I....L........EEWQ....K.........K.........K..............I..............A..E..M..G.PV..QW..L..TTQ..................KKA....VD..K.VIF.LL.S.N....D....V....S...P..R..C.D...G.T...C..G....R.....S...D.G...S..P.H..E.NSQ..............................................................-DLF.P..L..AFNLF...................CSDL.RS..........QTPL.H.KY...M.V..VYF....R......E......A......D.......T............K......D.......E...Y...S..G...L..SI.......CPR..Y..HL..M..KD..APAFCTEL..................................................................
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A0A2K5J9W3_COLAP/327-473               ................................i-KVLVVYPS...DI.CF...H.-..H...TI.C.YFTEFLQ.NH.C...RSEV..I....L........EKWQ....K.........K.........K..............I..............A..E..M..G.PV..QW..L..ATQ..................KKA....AD..K.VVF.LL.S.N....D....V....N...S..V..C.D...G.T...C..A....K.....S...E.G...S..P.S..E.NSQ..............................................................-DLF.P..L..AFNLF...................CSDL.RS..........QTHL.H.KY...V.V..VYF....R......E......T......D.......T............K......D.......N...Y...N..A...L..SV.......CPK..Y..HL..M..KD..ATAF----sch...............................................................
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A0A6P6I063_PUMCO/396-537               .................................RKVFITYSM...DT.AT...E.-..-...-V.V.KFVNFLL.VN.-...GFQT..A....I........DIFE....D.........-.........R..............I..............R..G..I..D.II..KW..M..ERY..................LRD....TV..M.IIV.AI.-.-....S....P....K...Y..K..Q.D...V.E...G..A....E.....S...Q.L...D..E.D..E.HGL..............................................................HTKY.I..H..RMMQI...................--EF.IKq........gSMNF.-.RF...I.P..VLF....P......N......A......K.......K............E......H.......V...P...T..W...L..QN.......THI..Y..SW..P..KN..KKNILLRL..................................................................
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A0A6A5FIY3_PERFL/495-673               ...............................gh--VVLLYPS..dDN.QA...L.P..E...LM.N.YLGSSLQ.GL.-...GFSV..S....L........DLWS....Q.........A.........E..............L..............S..V..L..G.PV..PW..L..HSRln..............rlQKQ....GG..K.VVL.VL.T.Q....A....A....W...I..R..A.E...E.W...GarS....W.....E...R.N...T..P.K..E.RNRvmeeeeae.............................................rlytasspcVDVF.T..A..SLSCV...................LADY.LQ..........GRAG.E.RF...M.L..VQF....E......S......L......P.......P............EppggfrP.......L...P...E..L...F..RG.......LHV..Y..SL..P..SQ..SLGFLTEL..................................................................
A0A2Y9LKS0_DELLE/400-542               .................................RKVFITYSM...DT.AM...E.-..-...-V.V.KFVNFLL.VN.-...GFQT..A....I........DIFE....D.........-.........R..............I..............R..G..I..D.II..KW..M..ERY..................LRD....KT..V.MII.VA.I.-....S....P....K...Y..K..Q.D...V.E...G..A....E.....S...Q.L...D..E.D..E.HGL..............................................................HTKY.I..H..RMMQI...................--EF.IKq........gSMNF.-.RF...I.P..VLF....P......N......A......K.......K............E......H.......V...P...T..W...L..QN.......THI..Y..SW..P..KN..KKNILLRL..................................................................
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G3GX29_CRIGR/335-472                   .................................RPILLLHAA...DS.EA...Q.R..R...LV.G.ALAELLR.TA.Lg.gGRDV..I....V........DLWE....G.........T.........H..............V..............A..R..I..G.PL..PW..F..WASre..............rvVRE....QG..T.VLL.LW.N.-....-....-....-...-..-..C.A...G.P...S..P....A.....G...S.G...D..P.H..P.ASI..............................................................----.-..R..TLLCA...................----.--..........--AP.R.RL...L.L..AYF...sR......L......C......A.......K............G......D.......I...P...Q..P...L..RA.......LPR..Y..RL..L..RD..LPRLLRAL..................................................................
A0A6P7NAU4_BETSP/233-390               ................................p-TVLVIYSH...DH.YL...Y.R..D...IV.L.KLCAFLQ.AK.C...GTKV..L....V........DLLD....S.........T.........S..............V..............N..M..V..G.RV..GW..L..ERQrq..............qlKNP....SD..K.ILV.LC.S.Q....G....V....Q...A..K..W.R...A.I...C..G....H.....D...R.V...T..L.K..E.DLLs...........................................................ptDDML.T..P..FLNLF...................LPDM.HQ..........AGTL.G.KY...V.V..AYF...dD......I......S......T.......E............E......D.......V...P...S..V...F..DI.......AVK..Y..KL..M..KH..FEELYFR-i.................................................................
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M3W0K4_FELCA/356-511                   .................................PKVFLCYSS..kDG.QN...H.M..N...VV.R.CFAYFLQ.DF.C...GCEV..A....L........DLWE....D.........F.........S..............L..............C..R..E..G.QR..EW..V..IQK..................IHE....SQ..F.IIV.VC.S.K....G....M....K...Y..F..V.D...K.K...N..Y....K.....H...K.G...S..G.R..G.SGK..............................................................GELF.L..V..AVSAIa................ekLRQA.KQs........sSAQL.S.KF...I.T..VYF....D......Y......S......C.......E............G......D.......V...P...G..I...L..DL.......STK..Y..KL..M..DN..LPQLCSHL..................................................................
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A0A3S2P985_ORYJA/1-80                  ...............................ma---------...--.--...-.-..-...--.-.-------.--.-...-TQV..C....L........DLWD....S.........L.........G..............V..............A..E..E..G.YM..SW..Y..CRQ..................IQE....SD..F.ILV.IC.S.P....G....L....K...R..R..S.E...L.P...G..G....-.....-...-.-...-..-.-..-.---..............................................................----.-..-..-----...................----.--..........----.-.--...-.-..---....-......-......-......-.......-............-......-.......-...-...-..-...-..--.......---..-..--..-..--..--------ddedeealsfspnahmseavirliaeevg.....................................
Q73LP6_TREDE/1-145                     .................................MKVFISYAW...TN.NE...Y.T..S...KI.L.LLAERLM.SD.-...GVET..I....I........DKWD....L.........-.........-..............-..............-..S..A..G.QD..KY..A..FMEqm..............iqDSS....ID..H.VLI.ML.N.-....-....-....-...R..E..Y.K...Q.K...S..D....E.....R...K.G...G..V.G..T.EAQiissd...................................................lynkvdQTKF.I..P..IVIEK...................----.--..........DDSG.R.PY...L.P..IYL....N......N......-......-.......-............-......-.......-...-...-..-...-..--.......---..-..--..-..--..--------riyidlsenenceyryeellrliy..........................................
A0A6J3S9K7_TURTR/383-542               .................................RKVWIVYSA...DH.PL...Y.V..D...VV.L.KFAQFLL.TV.C...GTEV..A....L........DLLE....E.........Q.........A..............I..............S..E..A..G.VM..TW..V..GRRkq..............evVEG....NS..K.IIV.LC.S.R....G....T....R...A..K..W.Q...A.I...L..G....W.....E...D.A...A..V.Q..L.RCDrg.........................................................kpaGDLF.T..A..AMNMI...................LPDF.KR..........PACF.G.TY...I.V..CYF...sD......I......S......C.......E............A......D.......I...P...E..L...F..NI.......TSC..Y..AL..M..DK..FEEVYFR-i.................................................................
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A0A669D0C7_ORENI/1-99                  .................mdvnkwtdsflkdplt---------...--.--...-.-..-...--.-.-------.--.-...----..-....-........----....-.........-.........-..............-..............-..-..-..-.--..--..-..---..................---....--..-.LII.IA.I.-....-....-....-...-..S..P.K...Y.K...E..D....I.....E...G.P...A..V.D..S.HGL..............................................................HTKY.I..H..SKMQN...................--EF.IQ.........qGSLN.F.RF...I.P..VLF....L......C......A......S.......Q............K......H.......V...P...S..W...L..QN.......TRV..Y..RW..P..QD..TEDLLLRL..................................................................
A0A3P8RNW4_AMPPE/345-502               .................................PKVLVIYSQ...DH.HL...Y.R..D...IV.L.KLCSFLQ.AK.C...GTKV..L....V........DLLD....S.........T.........S..............V..............S..M..V..G.RH..RW..L..EWQrq..............qlKNP....SD..K.ILV.LC.S.Q....G....V....Q...A..K..W.R...A.M...C..G....Q.....R...P.V...M..L.R..E.DITs...........................................................ptDDML.T..P..FLNLF...................LTDM.HQ..........AGMR.S.KY...M.V..AYF...gD......I......G......S.......E............L......D.......V...P...S..V...F..DI.......AVK..Y..NL..M..KH..FEELYFR-i.................................................................
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