#=GF ID   SH3_2
#=GF AC   PF07653.21
#=GF DE   Variant SH3 domain
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Manual
#=GF GA   21.80 21.80;
#=GF TC   21.80 21.80;
#=GF NC   21.70 21.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF WK   SH3_domain
#=GF CL   CL0010
#=GF RN   [1]
#=GF RM   12169629
#=GF RT   Diverse recognition of non-PxxP peptide ligands by the SH3
#=GF RT   domains from p67(phox), Grb2 and Pex13p. 
#=GF RA   Kami K, Takeya R, Sumimoto H, Kohda D; 
#=GF RL   EMBO J 2002;21:4268-4276.
#=GF DR   INTERPRO; IPR001452;
#=GF DR   PROSITE; PDOC50002;
#=GF DR   PRINTS; PR00452;
#=GF DR   SCOP; 1shf; sf;
#=GF DR   HOMSTRAD; sh3;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   SH3 (Src homology 3) domains are often indicative of a protein
#=GF CC   involved in  signal transduction related to cytoskeletal
#=GF CC   organisation. First described in the Src cytoplasmic tyrosine
#=GF CC   kinase Swiss:P12931. The structure is a partly opened beta
#=GF CC   barrel.
#=GF SQ   63524
#=GS A0A8C7DRW3_ONCKI/230-294      AC A0A8C7DRW3.1
#=GS A0A7L2X808_9PASS/5-61         AC A0A7L2X808.1
#=GS A0A3Q0CVS1_MESAU/10-63        AC A0A3Q0CVS1.1
#=GS A0A668SCD0_OREAU/197-259      AC A0A668SCD0.1
#=GS A0A8C8Y064_PANLE/376-433      AC A0A8C8Y064.1
#=GS A0A7K8DGE6_9CORV/580-640      AC A0A7K8DGE6.1
#=GS A0A6J3K078_9HYME/1308-1373    AC A0A6J3K078.1
#=GS A0A8C3Z7G8_9TELE/508-563      AC A0A8C3Z7G8.1
#=GS A0A8C9QN01_SPEDA/170-223      AC A0A8C9QN01.1
#=GS A0A091VD08_NIPNI/2-65         AC A0A091VD08.1
#=GS A0A668TN60_OREAU/2-46         AC A0A668TN60.1
#=GS A0A6P5E0C7_BOSIN/204-260      AC A0A6P5E0C7.1
#=GS G1LLN3_AILME/528-581          AC G1LLN3.2
#=GS A0A2U4CPI9_TURTR/4-60         AC A0A2U4CPI9.1
#=GS A0A6P7JSH9_9TELE/1102-1160    AC A0A6P7JSH9.1
#=GS A0A7K6BGX8_UPUEP/473-533      AC A0A7K6BGX8.1
#=GS A0A8B7VJB9_CASCN/588-641      AC A0A8B7VJB9.1
#=GS A0A8V0Z2K3_CHICK/2465-2545    AC A0A8V0Z2K3.1
#=GS A0A4V4N1H8_9BASI/5-60         AC A0A4V4N1H8.1
#=GS A0A6J1YHX5_ACIJB/229-291      AC A0A6J1YHX5.1
#=GS A0A4D9DRA3_9SAUR/537-599      AC A0A4D9DRA3.1
#=GS A0A1S3LUN2_SALSA/685-748      AC A0A1S3LUN2.1
#=GS F6T6Y1_MACMU/658-722          AC F6T6Y1.1
#=GS A0A6P9BPF2_PANGU/531-584      AC A0A6P9BPF2.1
#=GS A0A3Q2WFI1_HAPBU/158-213      AC A0A3Q2WFI1.1
#=GS A0A8R1U2J0_ONCVO/2334-2396    AC A0A8R1U2J0.1
#=GS A0A8C4VCW5_FALTI/85-138       AC A0A8C4VCW5.1
#=GS A0A6J1TNR6_9SAUR/1066-1124    AC A0A6J1TNR6.1
#=GS A0A6P3X9G2_DINQU/1194-1256    AC A0A6P3X9G2.1
#=GS A0A2K6TEM2_SAIBB/239-294      AC A0A2K6TEM2.1
#=GS A0A8V5HIA2_MELUD/509-571      AC A0A8V5HIA2.1
#=GS A0A8C5PMV8_9ANUR/1258-1314    AC A0A8C5PMV8.1
#=GS A0A8D0FQS4_STROC/312-366      AC A0A8D0FQS4.1
#=GS A0A8U0USA9_MUSPF/719-772      AC A0A8U0USA9.1
#=GS A0A6P6LF84_CARAU/246-301      AC A0A6P6LF84.1
#=GS A0A7N4NX67_SARHA/236-299      AC A0A7N4NX67.1
#=GS A0A6J3RJF2_TURTR/604-664      AC A0A6J3RJF2.1
#=GS A0A672TP00_STRHB/43-99        AC A0A672TP00.1
#=GS A0A8J4L3S4_APTPA/561-623      AC A0A8J4L3S4.1
#=GS A0A4W6FKA2_LATCA/199-263      AC A0A4W6FKA2.1
#=GS G5AT21_HETGA/382-439          AC G5AT21.1
#=GS A0A7L2BUU7_9PASS/15-64        AC A0A7L2BUU7.1
#=GS A0A8M3AJW2_DANRE/169-222      AC A0A8M3AJW2.1
#=GS A0A8C0JLE4_CANLU/49-105       AC A0A8C0JLE4.1
#=GS A0A7L2MBA9_9SYLV/84-137       AC A0A7L2MBA9.1
#=GS A0A7J7R371_PIPKU/547-600      AC A0A7J7R371.1
#=GS A0A6J1TNJ5_9SAUR/299-351      AC A0A6J1TNJ5.1
#=GS A0A8C9M5N4_PANTA/299-378      AC A0A8C9M5N4.1
#=GS A0A803SQN6_ANOCA/1009-1061    AC A0A803SQN6.1
#=GS A0A7J8HWF2_ROUAE/348-402      AC A0A7J8HWF2.1
#=GS A0A7E6EWW2_OCTVU/15-71        AC A0A7E6EWW2.1
#=GS A0A8C2TJ92_COTJA/240-295      AC A0A8C2TJ92.1
#=GS A0A553NIY8_9TELE/297-357      AC A0A553NIY8.1
#=GS A0A672UL70_STRHB/549-602      AC A0A672UL70.1
#=GS A0A8B9PG85_APTOW/467-529      AC A0A8B9PG85.1
#=GS A0A8M9QEN7_DANRE/280-339      AC A0A8M9QEN7.1
#=GS A0A8I3MNX3_CANLF/615-674      AC A0A8I3MNX3.1
#=GS A0A8C0E3M8_BALMU/162-225      AC A0A8C0E3M8.1
#=GS A0A8C3ID75_CHRPI/886-938      AC A0A8C3ID75.1
#=GS A0A3Q3A0H9_KRYMA/515-568      AC A0A3Q3A0H9.1
#=GS A0A6P5LAE4_PHACI/867-920      AC A0A6P5LAE4.1
#=GS A0A8C4NMD9_DICLA/448-509      AC A0A8C4NMD9.2
#=GS A0A7M7QM19_NASVI/534-596      AC A0A7M7QM19.1
#=GS A0A384AJP0_BALAS/448-501      AC A0A384AJP0.1
#=GS A0A8B9NKH4_9AVES/972-1024     AC A0A8B9NKH4.1
#=GS A0A2K5CG32_AOTNA/508-570      AC A0A2K5CG32.1
#=GS A0A8B9RY09_9AVES/815-870      AC A0A8B9RY09.1
#=GS A0A671TZS1_SPAAU/257-312      AC A0A671TZS1.1
#=GS A0A8I3Q801_CANLF/1225-1287    AC A0A8I3Q801.1
#=GS A0A8B8FY56_9HEMI/2432-2484    AC A0A8B8FY56.1
#=GS A0A3Q2WNJ4_HAPBU/806-867      AC A0A3Q2WNJ4.1
#=GS A0A816UFP3_9BILA/922-976      AC A0A816UFP3.1
#=GS A0A8C3VWZ1_9CETA/2-43         AC A0A8C3VWZ1.1
#=GS A0A7L3FT26_9GRUI/24-80        AC A0A7L3FT26.1
#=GS A0A8I3MIK9_CANLF/674-733      AC A0A8I3MIK9.1
#=GS U3JJ13_FICAL/572-634          AC U3JJ13.2
#=GS A0A7K9B1B4_DRONO/1229-1290    AC A0A7K9B1B4.1
#=GS A0A337S3A7_FELCA/132-195      AC A0A337S3A7.2
#=GS A0A8V5HIA8_MELUD/516-578      AC A0A8V5HIA8.1
#=GS A0A6J1QDX1_9HYME/236-300      AC A0A6J1QDX1.1
#=GS A0A7L1NE18_RHICY/659-723      AC A0A7L1NE18.1
#=GS B4HMZ4_DROSE/61-115           AC B4HMZ4.1
#=GS A0A3Q3L4E9_9LABR/219-278      AC A0A3Q3L4E9.1
#=GS A0A2K6RAW5_RHIRO/5-61         AC A0A2K6RAW5.1
#=GS A0A668RI41_OREAU/159-212      AC A0A668RI41.1
#=GS A0A8N5F2V8_GEOFO/559-612      AC A0A8N5F2V8.1
#=GS A0A667J6H4_LYNCA/723-777      AC A0A667J6H4.1
#=GS A0A8C9Q6C3_SPEDA/432-485      AC A0A8C9Q6C3.1
#=GS A0A851Y6G4_EOLRO/659-723      AC A0A851Y6G4.1
#=GS A0A7K8AB09_9CORV/164-219      AC A0A7K8AB09.1
#=GS A0A668W7R8_OREAU/790-842      AC A0A668W7R8.1
#=GS W6ULG1_ECHGR/610-663          AC W6ULG1.1
#=GS M0R5T5_RAT/157-210            AC M0R5T5.3
#=GS A0A154PKC6_DUFNO/754-806      AC A0A154PKC6.1
#=GS A0A8C3Y5E6_CATUS/1400-1462    AC A0A8C3Y5E6.1
#=GS A0A2K5F7I5_AOTNA/595-654      AC A0A2K5F7I5.1
#=GS A0A151MSU5_ALLMI/558-611      AC A0A151MSU5.1
#=GS A0A8I6SP49_CIMLE/998-1060     AC A0A8I6SP49.1
#=GS A0A851XZ55_EOLRO/84-137       AC A0A851XZ55.1
#=GS A0A671TY35_SPAAU/391-445      AC A0A671TY35.1
#=GS A0A1S3PQE5_SALSA/627-690      AC A0A1S3PQE5.1
#=GS A0A8C4WW99_EPTBU/155-208      AC A0A8C4WW99.1
#=GS F6QIE9_MACMU/1036-1089        AC F6QIE9.3
#=GS A0A6P8QH77_GEOSA/962-1015     AC A0A6P8QH77.1
#=GS A0A7N8XL46_9TELE/81-136       AC A0A7N8XL46.1
#=GS A0A7K8U732_OCEOC/282-335      AC A0A7K8U732.1
#=GS A0A6P6R999_CARAU/1097-1155    AC A0A6P6R999.1
#=GS A0A8B9RZ12_9AVES/318-372      AC A0A8B9RZ12.1
#=GS A0A1S3GXR2_DIPOR/359-416      AC A0A1S3GXR2.1
#=GS A0A8C9Y3U4_SANLU/167-220      AC A0A8C9Y3U4.1
#=GS A0A7L4DGY7_9AVES/12-61        AC A0A7L4DGY7.1
#=GS A0A4Z2GRI9_9TELE/50-104       AC A0A4Z2GRI9.1
#=GS A0A1V4J849_PATFA/273-328      AC A0A1V4J849.1
#=GS A0A8C5IPD0_JUNHY/580-640      AC A0A8C5IPD0.1
#=GS A0A8J5ZH93_GALPY/1451-1502    AC A0A8J5ZH93.1
#=GS A0A8B8D6E0_CRAVI/518-583      AC A0A8B8D6E0.1
#=GS A0A340X5V8_LIPVE/167-220      AC A0A340X5V8.1
#=GS A0A2U9CMP4_SCOMX/2474-2529    AC A0A2U9CMP4.1
#=GS A0A6P7JI89_9TELE/2081-2142    AC A0A6P7JI89.1
#=GS A0A8C9EF71_PHOSS/55-110       AC A0A8C9EF71.1
#=GS A0A8C6TNU9_9GOBI/108-168      AC A0A8C6TNU9.1
#=GS A0A6G0IBU6_LARCR/223-282      AC A0A6G0IBU6.1
#=GS A0A8C0C4G5_BALMU/650-703      AC A0A8C0C4G5.1
#=GS A0A815NZY3_9BILA/602-654      AC A0A815NZY3.1
#=GS A0A851YDR8_9AVES/812-867      AC A0A851YDR8.1
#=GS A0A3Q7P5S1_CALUR/1-54         AC A0A3Q7P5S1.1
#=GS W5NXK8_SHEEP/438-498          AC W5NXK8.1
#=GS A0A671KL92_9TELE/556-610      AC A0A671KL92.1
#=GS A0A0N4UDH9_DRAME/283-338      AC A0A0N4UDH9.1
#=GS A0A8D2LNW5_VARKO/854-912      AC A0A8D2LNW5.1
#=GS A0A423VQQ5_9PEZI/287-353      AC A0A423VQQ5.1
#=GS H0X1K8_OTOGA/526-580          AC H0X1K8.1
#=GS A0A6J1ZQL8_ACIJB/1035-1088    AC A0A6J1ZQL8.1
#=GS A0A4W5NLP1_9TELE/506-568      AC A0A4W5NLP1.1
#=GS D8M002_BLAHO/592-645          AC D8M002.1
#=GS A0A2Y9E6M4_TRIMA/792-846      AC A0A2Y9E6M4.1
#=GS A0A7N4NTD5_SARHA/115-168      AC A0A7N4NTD5.1
#=GS A0A7J7VCZ0_PIPKU/608-661      AC A0A7J7VCZ0.1
#=GS A0A2G8JS10_STIJA/109-162      AC A0A2G8JS10.1
#=GS H3AB18_LATCH/42-98            AC H3AB18.1
#=GS H0XD66_OTOGA/1175-1237        AC H0XD66.1
#=GS A0A8C3VPU4_9CETA/4-60         AC A0A8C3VPU4.1
#=GS R7TFG5_CAPTE/40-95            AC R7TFG5.1
#=GS A0A1S3S8Y9_SALSA/279-334      AC A0A1S3S8Y9.1
#=GS A0A852AN28_9CORV/165-218      AC A0A852AN28.1
#=GS A0A7K8WJ91_9FURN/67-124       AC A0A7K8WJ91.1
#=GS A0A8J4UD82_CLAMG/28-81        AC A0A8J4UD82.1
#=GS A0A7L3XLG1_9AVES/575-634      AC A0A7L3XLG1.1
#=GS A0A6J3EX50_SAPAP/285-345      AC A0A6J3EX50.1
#=GS A0A7K9KFJ4_9PASE/359-414      AC A0A7K9KFJ4.1
#=GS A0A5N3X1K2_MUNRE/1776-1835    AC A0A5N3X1K2.1
#=GS A0A7K6QYN2_9PASS/15-68        AC A0A7K6QYN2.1
#=GS A0A6J2UXU0_CHACN/584-644      AC A0A6J2UXU0.1
#=GS A0A8D0H6C4_SPHPU/209-262      AC A0A8D0H6C4.1
#=GS A0A8N5F2V1_GEOFO/627-680      AC A0A8N5F2V1.1
#=GS H2PH18_PONAB/510-567          AC H2PH18.3
#=GS G1NYK2_MYOLU/596-658          AC G1NYK2.1
#=GS A0A8B7VR52_CASCN/874-936      AC A0A8B7VR52.1
#=GS A0A7K4YPY5_BUCAB/3-66         AC A0A7K4YPY5.1
#=GS A0A7K6JEW8_9CORV/505-560      AC A0A7K6JEW8.1
#=GS A0A6P7T732_OCTVU/1120-1178    AC A0A6P7T732.1
#=GS A0A091EXK7_CORBR/896-951      AC A0A091EXK7.1
#=GS A0A7K8B732_9CORV/258-336      AC A0A7K8B732.1
#=GS A0A8B7R5W2_HIPAR/590-650      AC A0A8B7R5W2.1
#=GS A0A8B9C390_9AVES/165-218      AC A0A8B9C390.1
#=GS A0A2K5KXP3_CERAT/875-927      AC A0A2K5KXP3.1
#=GS A0A6J3QKB4_TURTR/1578-1637    AC A0A6J3QKB4.1
#=GS A0A671Y935_SPAAU/429-482      AC A0A671Y935.1
#=GS A0A6J3HZE1_SAPAP/234-296      AC A0A6J3HZE1.1
#=GS A0A4W4GLF0_ELEEL/702-753      AC A0A4W4GLF0.1
#=GS A0A6I9NIH6_9TELE/129-182      AC A0A6I9NIH6.1
#=GS A0A2K6RIQ1_RHIRO/390-447      AC A0A2K6RIQ1.1
#=GS A0A7L3AT99_9AVES/70-124       AC A0A7L3AT99.1
#=GS A0A671PKL6_9TELE/421-483      AC A0A671PKL6.1
#=GS A0A8B9ZU54_9AVES/791-842      AC A0A8B9ZU54.1
#=GS A0A8C9A6B0_PROSS/510-565      AC A0A8C9A6B0.1
#=GS A0A8C3JMS7_9CHAR/1002-1054    AC A0A8C3JMS7.1
#=GS A0A7L0KBE3_CHATO/1669-1749    AC A0A7L0KBE3.1
#=GS R4GB75_ANOCA/623-686          AC R4GB75.2
#=GS A0A7E6DBS1_9CHIR/555-608      AC A0A7E6DBS1.1
#=GS A0A7L0QMS2_SETKR/24-80        AC A0A7L0QMS2.1
#=GS A0A7L2Z3R8_JACJC/897-952      AC A0A7L2Z3R8.1
#=GS A0A8C4DAV2_DICLA/381-435      AC A0A8C4DAV2.1
#=GS A0A7N5KAK6_AILME/149-202      AC A0A7N5KAK6.1
#=GS A0A4W2DEP3_BOBOX/218-276      AC A0A4W2DEP3.1
#=GS A0A5J5CB47_9PERO/214-269      AC A0A5J5CB47.1
#=GS A0A096M5Y5_POEFO/266-325      AC A0A096M5Y5.1
#=GS A0A8C8DMI9_9TELE/627-691      AC A0A8C8DMI9.1
#=GS A0A4W5QH29_9TELE/459-509      AC A0A4W5QH29.1
#=GS A0A1U7S4U5_ALLSI/3-59         AC A0A1U7S4U5.2
#=GS A0A653C093_CALMS/6-65         AC A0A653C093.1
#=GS A0A8B9YZR3_9AVES/915-970      AC A0A8B9YZR3.1
#=GS A0A673BK67_9TELE/87-136       AC A0A673BK67.1
#=GS A0A8C4URB9_FALTI/572-634      AC A0A8C4URB9.1
#=GS A0A6J2W1A6_CHACN/179-234      AC A0A6J2W1A6.1
#=GS A0A8C4SP81_ERPCA/163-216      AC A0A8C4SP81.1
#=GS F7AM84_HORSE/135-215          AC F7AM84.3
#=GS A0A8C9LW77_9PRIM/852-907      AC A0A8C9LW77.1
#=GS A0A093FNT4_TYTAL/349-414      AC A0A093FNT4.1
#=GS H0YQH7_TAEGU/1068-1126        AC H0YQH7.2
#=GS A0A3Q2VJ79_HAPBU/177-232      AC A0A3Q2VJ79.1
#=GS A0A0M0JUA6_9EUKA/373-426      AC A0A0M0JUA6.1
#=GS A0A8J1J6D7_XENTR/957-1012     AC A0A8J1J6D7.1
#=GS A0A673I2S7_9TELE/161-214      AC A0A673I2S7.1
#=GS A0A7L0BCF5_9AVES/368-423      AC A0A7L0BCF5.1
#=GS A0A8I6SNM6_CIMLE/1024-1086    AC A0A8I6SNM6.1
#=GS A0A7L0JXW9_CHATO/387-445      AC A0A7L0JXW9.1
#=GS A0A8H5LTD6_9AGAR/22-76        AC A0A8H5LTD6.1
#=GS A0A8C4SQE3_ERPCA/46-106       AC A0A8C4SQE3.1
#=GS A0A7K4R9U3_9TYRA/659-723      AC A0A7K4R9U3.1
#=GS A0A672LI72_SINGR/565-625      AC A0A672LI72.1
#=GS A0A8C7IIR9_ONCKI/283-342      AC A0A8C7IIR9.1
#=GS A0A6P6NGA1_CARAU/61-122       AC A0A6P6NGA1.1
#=GS A0A8C6FGD0_MOSMO/129-182      AC A0A8C6FGD0.1
#=GS A0A3Q4HWV9_NEOBR/405-469      AC A0A3Q4HWV9.1
#=GS A0A7K5FLF6_PROAR/240-295      AC A0A7K5FLF6.1
#=GS A0A0P7V7U7_SCLFO/220-279      AC A0A0P7V7U7.1
#=GS A0A6P5L4A6_PHACI/1083-1136    AC A0A6P5L4A6.1
#=GS A0A6P4YDR4_BRABE/7-62         AC A0A6P4YDR4.1
#=GS A0A7L1UQW1_SITEU/734-787      AC A0A7L1UQW1.1
#=GS A0A4Z2BTW1_9TELE/991-1050     AC A0A4Z2BTW1.1
#=GS A0A5A9PL69_9TELE/167-220      AC A0A5A9PL69.1
#=GS A0A3Q3AYK9_KRYMA/585-645      AC A0A3Q3AYK9.1
#=GS A0A4W2EYK1_BOBOX/1073-1131    AC A0A4W2EYK1.1
#=GS A0A667XQ77_9TELE/527-589      AC A0A667XQ77.1
#=GS A0A8C9F762_PAVCR/489-542      AC A0A8C9F762.1
#=GS A0A7K5QZM6_9PASE/127-180      AC A0A7K5QZM6.1
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